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Search of human proteins with 21361403
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361403 thioredoxin 2 precursor [Homo sapiens]
(166 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361403 thioredoxin 2 precursor [Homo sapiens] 337 4e-93
gi|50592994 thioredoxin [Homo sapiens] 69 2e-12
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s... 61 5e-10
gi|4758304 protein disulfide isomerase A4 [Homo sapiens] 60 7e-10
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens] 60 7e-10
gi|5803121 protein disulfide isomerase A5 [Homo sapiens] 56 2e-08
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ... 54 5e-08
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap... 54 5e-08
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 54 6e-08
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 54 6e-08
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 54 6e-08
gi|94966757 protein disulfide isomerase A2 [Homo sapiens] 54 8e-08
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul... 54 8e-08
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s... 51 4e-07
gi|5031973 protein disulfide isomerase A6 [Homo sapiens] 49 3e-06
gi|38505222 thioredoxin domain containing 10 [Homo sapiens] 47 1e-05
gi|4759274 thioredoxin-like 1 [Homo sapiens] 43 1e-04
gi|51510891 thioredoxin domain containing 8 [Homo sapiens] 42 3e-04
gi|95113651 glutaredoxin 3 [Homo sapiens] 41 5e-04
gi|151101292 thioredoxin domain containing 1 [Homo sapiens] 41 5e-04
gi|28372543 protein disulfide isomerase-like, testis expressed [... 40 0.001
gi|18104959 thioredoxin domain containing 9 [Homo sapiens] 37 0.006
gi|148839372 thioredoxin domain containing 3 [Homo sapiens] 36 0.013
gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo sap... 34 0.066
gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo sap... 34 0.066
gi|30023828 thioredoxin domain containing 6 [Homo sapiens] 33 0.086
gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo sa... 33 0.11
gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo sapi... 33 0.11
gi|7705696 thioredoxin domain containing 12 [Homo sapiens] 32 0.33
gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens] 31 0.56
>gi|21361403 thioredoxin 2 precursor [Homo sapiens]
Length = 166
Score = 337 bits (863), Expect = 4e-93
Identities = 166/166 (100%), Positives = 166/166 (100%)
Query: 1 MAQRLLLRRFLASVISRKPSQGQWPPLTSRALQTPQCSPGGLTVTPNPARTIYTTRISLT 60
MAQRLLLRRFLASVISRKPSQGQWPPLTSRALQTPQCSPGGLTVTPNPARTIYTTRISLT
Sbjct: 1 MAQRLLLRRFLASVISRKPSQGQWPPLTSRALQTPQCSPGGLTVTPNPARTIYTTRISLT 60
Query: 61 TFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDD 120
TFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDD
Sbjct: 61 TFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDD 120
Query: 121 HTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKLIG 166
HTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKLIG
Sbjct: 121 HTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKLIG 166
>gi|50592994 thioredoxin [Homo sapiens]
Length = 105
Score = 68.6 bits (166), Expect = 2e-12
Identities = 34/85 (40%), Positives = 54/85 (63%), Gaps = 2/85 (2%)
Query: 81 VVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMK 140
VVVDF A WCGPCK++ P + ++++ V+ +VD+DD D+A E EV +PT K
Sbjct: 23 VVVDFSATWCGPCKMIKPFFHSL-SEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFK 81
Query: 141 NGDVVDKFVGIKDEDQLEAFLKKLI 165
G V +F G ++++LEA + +L+
Sbjct: 82 KGQKVGEFSG-ANKEKLEATINELV 105
>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
sapiens]
Length = 508
Score = 60.8 bits (146), Expect = 5e-10
Identities = 31/91 (34%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 81 VVVDFHAQWCGPCKILGPRLEKMVAK---QHGKVVMAKVDIDDHTDLAIEYEVSAVPTVL 137
++V+F+A WCG CK L P K K + ++ +AKVD + +DLA +Y V PT+
Sbjct: 44 LLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIK 103
Query: 138 AMKNGDVVD--KFVGIKDEDQLEAFLKKLIG 166
+NGD ++ ++ D + +LKK G
Sbjct: 104 FFRNGDTASPKEYTAGREADDIVNWLKKRTG 134
Score = 45.4 bits (106), Expect = 2e-05
Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 20/112 (17%)
Query: 67 GPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKM--VAKQHGKVVMAKVDIDDHTDL 124
G +F+D + + V V+F+A WCG CK L P +K+ K H +V+AK+D +
Sbjct: 374 GKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVE 433
Query: 125 AIE---------YEVSAVPTVLAMKNGDVVDKFV---------GIKDEDQLE 158
A++ + SA TV+ +D F G D+D LE
Sbjct: 434 AVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLE 485
>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
Length = 645
Score = 60.5 bits (145), Expect = 7e-10
Identities = 31/78 (39%), Positives = 44/78 (56%), Gaps = 3/78 (3%)
Query: 72 DRVVNSETPVVVDFHAQWCGPCKILGPRLEKM---VAKQHGKVVMAKVDIDDHTDLAIEY 128
D VVN ++V+F+A WCG CK L P EK ++K+ + +AKVD TDLA +
Sbjct: 188 DEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRF 247
Query: 129 EVSAVPTVLAMKNGDVVD 146
+VS PT+ + G D
Sbjct: 248 DVSGYPTLKIFRKGRPYD 265
Score = 55.5 bits (132), Expect = 2e-08
Identities = 28/96 (29%), Positives = 54/96 (56%), Gaps = 4/96 (4%)
Query: 72 DRVVNSETPVVVDFHAQWCGPCKILGPRLEK---MVAKQHGKVVMAKVDIDDHTDLAIEY 128
D V + V+++F+A WCG CK P EK ++ + + +AK+D + LA +
Sbjct: 73 DNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRF 132
Query: 129 EVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKL 164
+VS PT+ +K G VD + G + ++++ A ++++
Sbjct: 133 DVSGYPTIKILKKGQAVD-YEGSRTQEEIVAKVREV 167
Score = 50.1 bits (118), Expect = 9e-07
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 5/102 (4%)
Query: 67 GPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGK--VVMAKVDIDDHTDL 124
G F V++ + V+++F+A WCG CK L P + K G+ +V+AK+D +
Sbjct: 532 GKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVP 591
Query: 125 AIEYEVSAVPTVLAMKNGDVVD--KFV-GIKDEDQLEAFLKK 163
+ Y+V PT+ +GD + KF G +D + L F+++
Sbjct: 592 SDRYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEE 633
>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
Length = 505
Score = 60.5 bits (145), Expect = 7e-10
Identities = 37/128 (28%), Positives = 65/128 (50%), Gaps = 3/128 (2%)
Query: 42 LTVTPNPARTIYTTRISLTTFNIQDGPD-FQDRVVNSETP--VVVDFHAQWCGPCKILGP 98
L + P A + R++ + ++ D F+ R+ ++ + ++V+F A WCG CK L P
Sbjct: 6 LALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAP 65
Query: 99 RLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLE 158
E + G V +AKVD +T+ +Y VS PT+ ++G+ + G + D +
Sbjct: 66 EYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIV 125
Query: 159 AFLKKLIG 166
+ LKK G
Sbjct: 126 SHLKKQAG 133
Score = 46.6 bits (109), Expect = 1e-05
Identities = 25/68 (36%), Positives = 42/68 (61%), Gaps = 4/68 (5%)
Query: 72 DRVVNSETP-VVVDFHAQWCGPCKILGPRLEKMVAK--QHGKVVMAKVDIDDHTDLAIEY 128
D +VN+E V+++F+A WCG CK L P+ +++ K + +V+AK+D + D+ Y
Sbjct: 387 DEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAN-DVPSPY 445
Query: 129 EVSAVPTV 136
EV PT+
Sbjct: 446 EVRGFPTI 453
>gi|5803121 protein disulfide isomerase A5 [Homo sapiens]
Length = 519
Score = 55.8 bits (133), Expect = 2e-08
Identities = 29/76 (38%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
Query: 72 DRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKV----VMAKVDIDDHTDLAIE 127
D+ V + V+V FHA WCG CK + P EK HG+ V+A VD + LA
Sbjct: 287 DQFVKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVNKALAER 346
Query: 128 YEVSAVPTVLAMKNGD 143
+ +S PT+ KNG+
Sbjct: 347 FHISEFPTLKYFKNGE 362
Score = 46.6 bits (109), Expect = 1e-05
Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 2/76 (2%)
Query: 69 DFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDI--DDHTDLAI 126
DF+ + E P+++ F+A WC CK + P +K + G V+A +++ + ++
Sbjct: 161 DFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRGHAVLAGMNVYSSEFENIKE 220
Query: 127 EYEVSAVPTVLAMKNG 142
EY V PT+ + G
Sbjct: 221 EYSVRGFPTICYFEKG 236
Score = 31.2 bits (69), Expect = 0.43
Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 9/96 (9%)
Query: 67 GPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKM--VAKQHGKVVMAKVDI--DDHT 122
G +F++ + + +V+ F+A WC CK + P K K+ A VD D +
Sbjct: 404 GDNFRETLKKKKHTLVM-FYAPWCPHCKKVIPHFTATADAFKDDRKIACAAVDCVKDKNQ 462
Query: 123 DLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLE 158
DL + V PT G +K+ D D+ E
Sbjct: 463 DLCQQEAVKGYPTFHYYHYGKFAEKY----DSDRTE 494
>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
[Homo sapiens]
Length = 432
Score = 54.3 bits (129), Expect = 5e-08
Identities = 39/129 (30%), Positives = 59/129 (45%), Gaps = 18/129 (13%)
Query: 43 TVTPNPARTIYT-------TRISLTTFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKI 95
TVTP+ A + T ++LT N F D + T + F+A WCG CK
Sbjct: 304 TVTPSEAPVLAAEPEADKGTVLALTENN------FDDTIAEGIT--FIKFYAPWCGHCKT 355
Query: 96 LGPRLEKMVAKQH---GKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIK 152
L P E++ K+ V +A+VD ++ +Y V PT+L + G V + G +
Sbjct: 356 LAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGR 415
Query: 153 DEDQLEAFL 161
D D L F+
Sbjct: 416 DLDSLHRFV 424
Score = 53.5 bits (127), Expect = 8e-08
Identities = 27/82 (32%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Query: 83 VDFHAQWCGPCKILGPRLEKM-VAKQHGKVV-MAKVDIDDHTDLAIEYEVSAVPTVLAMK 140
+ F A WCG CK L P E++ + +H + V + KVD H +L +V PT+L +
Sbjct: 210 IKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFR 269
Query: 141 NGDVVDKFVGIKDEDQLEAFLK 162
+G VD++ G +D + L +++
Sbjct: 270 DGKKVDQYKGKRDLESLREYVE 291
Score = 46.2 bits (108), Expect = 1e-05
Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Query: 83 VDFHAQWCGPCKILGPRL----EKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLA 138
V F A WCG C+ L P +K + + KV +AKVD H+D+ V PT+
Sbjct: 82 VMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKL 141
Query: 139 MKNGDVVDKFVGIKDEDQLEAFL 161
K G K+ G +D LE ++
Sbjct: 142 FKPGQEAVKYQGPRDFQTLENWM 164
>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
sapiens]
Length = 324
Score = 54.3 bits (129), Expect = 5e-08
Identities = 39/129 (30%), Positives = 59/129 (45%), Gaps = 18/129 (13%)
Query: 43 TVTPNPARTIYT-------TRISLTTFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKI 95
TVTP+ A + T ++LT N F D + T + F+A WCG CK
Sbjct: 196 TVTPSEAPVLAAEPEADKGTVLALTENN------FDDTIAEGIT--FIKFYAPWCGHCKT 247
Query: 96 LGPRLEKMVAKQH---GKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIK 152
L P E++ K+ V +A+VD ++ +Y V PT+L + G V + G +
Sbjct: 248 LAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGR 307
Query: 153 DEDQLEAFL 161
D D L F+
Sbjct: 308 DLDSLHRFV 316
Score = 53.5 bits (127), Expect = 8e-08
Identities = 27/82 (32%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Query: 83 VDFHAQWCGPCKILGPRLEKM-VAKQHGKVV-MAKVDIDDHTDLAIEYEVSAVPTVLAMK 140
+ F A WCG CK L P E++ + +H + V + KVD H +L +V PT+L +
Sbjct: 102 IKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFR 161
Query: 141 NGDVVDKFVGIKDEDQLEAFLK 162
+G VD++ G +D + L +++
Sbjct: 162 DGKKVDQYKGKRDLESLREYVE 183
Score = 33.1 bits (74), Expect = 0.11
Identities = 18/55 (32%), Positives = 27/55 (49%)
Query: 107 QHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFL 161
+ KV +AKVD H+D+ V PT+ K G K+ G +D LE ++
Sbjct: 2 EDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWM 56
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 53.9 bits (128), Expect = 6e-08
Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
Query: 78 ETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVL 137
E V VDF A WCGPC+ + P + K H VV +VD D+ ++ E + VPT
Sbjct: 401 ERLVAVDFSATWCGPCRTIRPFFHALSVK-HEDVVFLEVDADNCEEVVRECAIMCVPTFQ 459
Query: 138 AMKNGDVVDKFVGIKDEDQLEAFLKKL 164
K + VD+ G E +LEA + +L
Sbjct: 460 FYKKEEKVDELCGALKE-KLEAVIAEL 485
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 53.9 bits (128), Expect = 6e-08
Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
Query: 78 ETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVL 137
E V VDF A WCGPC+ + P + K H VV +VD D+ ++ E + VPT
Sbjct: 468 ERLVAVDFSATWCGPCRTIRPFFHALSVK-HEDVVFLEVDADNCEEVVRECAIMCVPTFQ 526
Query: 138 AMKNGDVVDKFVGIKDEDQLEAFLKKL 164
K + VD+ G E +LEA + +L
Sbjct: 527 FYKKEEKVDELCGALKE-KLEAVIAEL 552
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 53.9 bits (128), Expect = 6e-08
Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
Query: 78 ETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVL 137
E V VDF A WCGPC+ + P + K H VV +VD D+ ++ E + VPT
Sbjct: 401 ERLVAVDFSATWCGPCRTIRPFFHALSVK-HEDVVFLEVDADNCEEVVRECAIMCVPTFQ 459
Query: 138 AMKNGDVVDKFVGIKDEDQLEAFLKKL 164
K + VD+ G E +LEA + +L
Sbjct: 460 FYKKEEKVDELCGALKE-KLEAVIAEL 485
>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
Length = 525
Score = 53.5 bits (127), Expect = 8e-08
Identities = 28/91 (30%), Positives = 53/91 (58%), Gaps = 5/91 (5%)
Query: 81 VVVDFHAQWCGPCKILGPRLEK---MVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVL 137
++V+F+A WCG C+ L P K ++A + V +AKVD +LA E+ V+ PT+
Sbjct: 62 LLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLK 121
Query: 138 AMKNGDVV--DKFVGIKDEDQLEAFLKKLIG 166
+NG+ +++ G +D + + +L++ +G
Sbjct: 122 FFRNGNRTHPEEYTGPRDAEGIAEWLRRRVG 152
Score = 35.4 bits (80), Expect = 0.023
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)
Query: 67 GPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAK--QHGKVVMAKVDIDDHTDL 124
G +F+ + V V F+A WC CK + P E + K H +++A++D +
Sbjct: 395 GKNFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATANELD 454
Query: 125 AIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKL 164
A + V PT+ G K + K LE F K L
Sbjct: 455 A--FAVHGFPTLKYFPAGP-GRKVIEYKSTRDLETFSKFL 491
>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
[Homo sapiens]
Length = 406
Score = 53.5 bits (127), Expect = 8e-08
Identities = 36/99 (36%), Positives = 53/99 (53%), Gaps = 14/99 (14%)
Query: 51 TIYTTRI-SLTTFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKM--VAKQ 107
T TT I SL T NI D ++N+ +V+F+A WC ++L P E+ V K+
Sbjct: 25 TPVTTEITSLDTENI-------DEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKE 77
Query: 108 H----GKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNG 142
+VV A+VD D H+D+A Y +S PT+ +NG
Sbjct: 78 EFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNG 116
>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
sapiens]
Length = 793
Score = 51.2 bits (121), Expect = 4e-07
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 71 QDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEV 130
Q+ N + P +VDF A WC PC+ L P L + +G++ +D H L Y +
Sbjct: 461 QNFPANDKEPWLVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTVHEGLCNMYNI 520
Query: 131 SAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKLI 165
A PT + N + ++ G +Q+ F++ L+
Sbjct: 521 QAYPTTVVF-NQSNIHEYEGHHSAEQILEFIEDLM 554
Score = 51.2 bits (121), Expect = 4e-07
Identities = 23/67 (34%), Positives = 34/67 (50%)
Query: 70 FQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYE 129
F ++V+ + V+DF+A WCGPC+ P E + GKV KVD + +
Sbjct: 680 FSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDCQAYAQTCQKAG 739
Query: 130 VSAVPTV 136
+ A PTV
Sbjct: 740 IRAYPTV 746
Score = 38.5 bits (88), Expect = 0.003
Identities = 14/55 (25%), Positives = 27/55 (49%)
Query: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTV 136
+VDF++ WC PC++L P ++M G + + +D + + V P +
Sbjct: 580 MVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQQYHSFCAQENVQRYPEI 634
Score = 32.7 bits (73), Expect = 0.15
Identities = 21/89 (23%), Positives = 39/89 (43%)
Query: 72 DRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVS 131
D VNS V+F++ C C L P + G + + V+ D L V+
Sbjct: 140 DAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCGDDRMLCRMKGVN 199
Query: 132 AVPTVLAMKNGDVVDKFVGIKDEDQLEAF 160
+ P++ ++G K+ G + ++ L +F
Sbjct: 200 SYPSLFIFRSGMAPVKYHGDRSKESLVSF 228
>gi|5031973 protein disulfide isomerase A6 [Homo sapiens]
Length = 440
Score = 48.5 bits (114), Expect = 3e-06
Identities = 23/68 (33%), Positives = 35/68 (51%)
Query: 69 DFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEY 128
+F V+ S++ +V+F+A WCG C+ L P +K V + VD D H L +Y
Sbjct: 34 NFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQY 93
Query: 129 EVSAVPTV 136
V PT+
Sbjct: 94 GVQGFPTI 101
Score = 47.4 bits (111), Expect = 6e-06
Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 70 FQDRVVNSETPVVVDFHAQWCGPCKILGPR----LEKMVAKQHGKVVMAKVDIDDHTDLA 125
F V++SE +V+F+A WCG CK L P ++ + GKV +A VD + LA
Sbjct: 170 FDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLA 229
Query: 126 IEYEVSAVPTVLAMKNGD 143
Y + PT+ + G+
Sbjct: 230 SRYGIRGFPTIKIFQKGE 247
>gi|38505222 thioredoxin domain containing 10 [Homo sapiens]
Length = 454
Score = 46.6 bits (109), Expect = 1e-05
Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 4/88 (4%)
Query: 82 VVDFHAQWCGPCKILGPRLEKMVAKQH---GKVVMAKVDIDDHTDLAIEYEVSAVPTVLA 138
+VDF+A WCG CK L P ++ + V + K+D ++ +A E+ V PT+
Sbjct: 45 LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
Query: 139 MKNGDVVDKFVGIKDEDQLEAFLKKLIG 166
+K GD+ + G + +D + F ++ G
Sbjct: 105 LK-GDLAYNYRGPRTKDDIIEFAHRVSG 131
>gi|4759274 thioredoxin-like 1 [Homo sapiens]
Length = 289
Score = 42.7 bits (99), Expect = 1e-04
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Query: 68 PDFQDRVVNSETPV-VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAI 126
PDFQ + + + + VV F + CGPC + P M + ++ + V +VD+ A
Sbjct: 11 PDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSM-SNKYPQAVFLEVDVHQCQGTAA 69
Query: 127 EYEVSAVPTVLAMKNGDVVDKFVG 150
+SA PT L +N +D++ G
Sbjct: 70 TNNISATPTFLFFRNKVRIDQYQG 93
>gi|51510891 thioredoxin domain containing 8 [Homo sapiens]
Length = 115
Score = 41.6 bits (96), Expect = 3e-04
Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 82 VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKN 141
VV F ++ CGPCK + P M K + V A VD+++ +LA + +PT K
Sbjct: 24 VVQFSSKRCGPCKRMFPVFHAMSVK-YQNVFFANVDVNNSPELAETCHIKTIPTFQMFKK 82
Query: 142 GDVVDKFVGIK 152
V F IK
Sbjct: 83 SQKVTLFSRIK 93
>gi|95113651 glutaredoxin 3 [Homo sapiens]
Length = 335
Score = 40.8 bits (94), Expect = 5e-04
Identities = 21/76 (27%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 75 VNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVP 134
+ +++ +VV F A W C + + ++ AK+ +V K++ + +++ +YE+S+VP
Sbjct: 28 LKAKSLLVVHFWAPWAPQCAQMNEVMAEL-AKELPQVSFVKLEAEGVPEVSEKYEISSVP 86
Query: 135 TVLAMKNGDVVDKFVG 150
T L KN +D+ G
Sbjct: 87 TFLFFKNSQKIDRLDG 102
>gi|151101292 thioredoxin domain containing 1 [Homo sapiens]
Length = 280
Score = 40.8 bits (94), Expect = 5e-04
Identities = 19/63 (30%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
Query: 82 VVDFHAQWCGPCKILGPRLEKMVA-KQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMK 140
+++F+A WC C+ L P E + +V +AKVD+ + L+ + ++A+PT+ K
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCK 107
Query: 141 NGD 143
+G+
Sbjct: 108 DGE 110
>gi|28372543 protein disulfide isomerase-like, testis expressed
[Homo sapiens]
Length = 584
Score = 39.7 bits (91), Expect = 0.001
Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 67 GPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAK--QHGKVVMAKVDI 118
G +F V + E V V F+A W CK+L P LE++ K H +++AK+D+
Sbjct: 394 GKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDV 447
>gi|18104959 thioredoxin domain containing 9 [Homo sapiens]
Length = 226
Score = 37.4 bits (85), Expect = 0.006
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 69 DFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEY 128
DF V SE VV F+ CKIL L +++K+H + K++++ L
Sbjct: 81 DFFQEVKESEN-VVCHFYRDSTFRCKILDRHLA-ILSKKHLETKFLKLNVEKAPFLCERL 138
Query: 129 EVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAF 160
+ +PT+ +K+G D VG D + F
Sbjct: 139 HIKVIPTLALLKDGKTQDYVVGFTDLGNTDDF 170
>gi|148839372 thioredoxin domain containing 3 [Homo sapiens]
Length = 588
Score = 36.2 bits (82), Expect = 0.013
Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Query: 72 DRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVM--AKVDIDDHTDLAIEYE 129
D ++ ++ V+D + WCGPC+ + P K+ + + ++ A + D+ L +
Sbjct: 21 DEMLQNKGLTVIDVYQAWCGPCRAMQPLFRKLKNELNEDEILHFAVAEADNIVTLQ-PFR 79
Query: 130 VSAVPTVLAMKNGDVVDKFVG 150
P L NG +++K G
Sbjct: 80 DKCEPVFLFSVNGKIIEKIQG 100
>gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo
sapiens]
Length = 604
Score = 33.9 bits (76), Expect = 0.066
Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 10/129 (7%)
Query: 17 RKPSQGQWPPLTSRALQTPQCSPGGLTVTPNPARTIYTTRISLTTFNIQDGPDFQDRVVN 76
R+ + G PP + L + G P A +Y+ LT + + V+
Sbjct: 2 RRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSA--LYSPSDPLT---LLQADTVRGAVLG 56
Query: 77 SETPVVVDFHAQWCGPCKILGP---RLEKMVAKQHGKVVMAKVDIDDHTDLAI--EYEVS 131
S + V+F A WCG C P L + V + +A +D + T+ A+ ++ +
Sbjct: 57 SRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIP 116
Query: 132 AVPTVLAMK 140
PTV K
Sbjct: 117 GFPTVRFFK 125
>gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo
sapiens]
Length = 747
Score = 33.9 bits (76), Expect = 0.066
Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 10/129 (7%)
Query: 17 RKPSQGQWPPLTSRALQTPQCSPGGLTVTPNPARTIYTTRISLTTFNIQDGPDFQDRVVN 76
R+ + G PP + L + G P A +Y+ LT + + V+
Sbjct: 2 RRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSA--LYSPSDPLT---LLQADTVRGAVLG 56
Query: 77 SETPVVVDFHAQWCGPCKILGP---RLEKMVAKQHGKVVMAKVDIDDHTDLAI--EYEVS 131
S + V+F A WCG C P L + V + +A +D + T+ A+ ++ +
Sbjct: 57 SRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIP 116
Query: 132 AVPTVLAMK 140
PTV K
Sbjct: 117 GFPTVRFFK 125
>gi|30023828 thioredoxin domain containing 6 [Homo sapiens]
Length = 263
Score = 33.5 bits (75), Expect = 0.086
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 10/81 (12%)
Query: 74 VVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAV 133
+++S+ VVD + WCGPCK + +KM + ++ + D D+ +Y
Sbjct: 1 MLSSKGLTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRLDVLEKYRGKCE 60
Query: 134 PTVLAMKNGDVVDKFVGIKDE 154
PT L F IKDE
Sbjct: 61 PTFL----------FYAIKDE 71
>gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo
sapiens]
Length = 258
Score = 33.1 bits (74), Expect = 0.11
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 7/72 (9%)
Query: 70 FQDRVVNSE------TPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVV-MAKVDIDDHT 122
F D+ ++ E +V+F A W C+ P + K + + KVD+ +T
Sbjct: 103 FNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYT 162
Query: 123 DLAIEYEVSAVP 134
D++ Y+VS P
Sbjct: 163 DVSTRYKVSTSP 174
>gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo
sapiens]
Length = 296
Score = 33.1 bits (74), Expect = 0.11
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 7/72 (9%)
Query: 70 FQDRVVNSE------TPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVV-MAKVDIDDHT 122
F D+ ++ E +V+F A W C+ P + K + + KVD+ +T
Sbjct: 141 FNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYT 200
Query: 123 DLAIEYEVSAVP 134
D++ Y+VS P
Sbjct: 201 DVSTRYKVSTSP 212
>gi|7705696 thioredoxin domain containing 12 [Homo sapiens]
Length = 172
Score = 31.6 bits (70), Expect = 0.33
Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 3/72 (4%)
Query: 69 DFQDRVVNSETPVVVDFHAQWCGPCKILGPRL---EKMVAKQHGKVVMAKVDIDDHTDLA 125
D + S P++V H WCG CK L P+ ++ H V++ D ++ D
Sbjct: 45 DGKKEAAASGLPLMVIIHKSWCGACKALKPKFAESTEISELSHNFVMVNLEDEEEPKDED 104
Query: 126 IEYEVSAVPTVL 137
+ +P +L
Sbjct: 105 FSPDGGYIPRIL 116
>gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens]
Length = 698
Score = 30.8 bits (68), Expect = 0.56
Identities = 27/136 (19%), Positives = 48/136 (35%), Gaps = 13/136 (9%)
Query: 13 SVISRKPSQGQWPPLTSRALQTPQCSP--------GGLTVTPNPARTIYTTRISLTTFNI 64
+ ++R P G P L +R P+ + V P R +
Sbjct: 6 AAVARSPGIGAGPALRARRSPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWV 65
Query: 65 QDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKM---VAKQHGKVVMAKVDIDDH 121
D + NS +V F++ WCG C P + V + +A +D +
Sbjct: 66 LDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEE 125
Query: 122 TDLAI--EYEVSAVPT 135
+ A+ +Y++ PT
Sbjct: 126 KNQAVCHDYDIHFYPT 141
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,420,251
Number of Sequences: 37866
Number of extensions: 283441
Number of successful extensions: 1017
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 943
Number of HSP's gapped (non-prelim): 68
length of query: 166
length of database: 18,247,518
effective HSP length: 95
effective length of query: 71
effective length of database: 14,650,248
effective search space: 1040167608
effective search space used: 1040167608
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.