Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 21361282
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361282 splicing factor, arginine/serine-rich 4 [Homo
sapiens]
(494 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 954 0.0
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 424 e-119
gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens] 297 1e-80
gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens] 297 1e-80
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 178 1e-44
gi|5902076 splicing factor, arginine/serine-rich 1 isoform 1 [Ho... 172 8e-43
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 150 3e-36
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 145 6e-35
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 145 6e-35
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 141 2e-33
gi|118582269 splicing factor, arginine/serine-rich 1 isoform 2 [... 136 4e-32
gi|4506903 splicing factor, arginine/serine-rich 9 [Homo sapiens] 136 5e-32
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 135 1e-31
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 135 1e-31
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 129 5e-30
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 129 8e-30
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 127 3e-29
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 120 4e-27
gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens] 113 3e-25
gi|16905517 FUS interacting protein (serine-arginine rich) 1 iso... 111 1e-24
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 110 2e-24
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 108 1e-23
gi|50962882 G patch domain containing 8 [Homo sapiens] 107 2e-23
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 106 6e-23
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 105 7e-23
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 105 7e-23
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 105 7e-23
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 103 4e-22
gi|52426743 cisplatin resistance-associated overexpressed protei... 101 1e-21
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 101 1e-21
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 954 bits (2465), Expect = 0.0
Identities = 494/494 (100%), Positives = 494/494 (100%)
Query: 1 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL 60
MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL
Sbjct: 1 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL 60
Query: 61 CGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDL 120
CGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDL
Sbjct: 61 CGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDL 120
Query: 121 KDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR 180
KDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR
Sbjct: 121 KDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR 180
Query: 181 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS 240
RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS
Sbjct: 181 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS 240
Query: 241 RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS 300
RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS
Sbjct: 241 RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS 300
Query: 301 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS 360
RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS
Sbjct: 301 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS 360
Query: 361 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS 420
REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS
Sbjct: 361 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS 420
Query: 421 ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS 480
ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS
Sbjct: 421 ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS 480
Query: 481 RSPSRSRSRSHSRS 494
RSPSRSRSRSHSRS
Sbjct: 481 RSPSRSRSRSHSRS 494
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 424 bits (1091), Expect = e-119
Identities = 239/361 (66%), Positives = 270/361 (74%), Gaps = 26/361 (7%)
Query: 1 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL 60
MPRVYIGRLSY RE+D++RFF GYG++LEVDLKNGYGFVEF+D RDADDAVYELNGK+L
Sbjct: 1 MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKEL 60
Query: 61 CGERVIVEHARGPRRDG---SYGSGRSGYGY---RRSGRDKYGPPTRTEYRLIVENLSSR 114
CGERVIVEHARGPRRD SYGS G GY R SGRDKYGPP RTEYRLIVENLSSR
Sbjct: 61 CGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSR 120
Query: 115 CSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVE 174
CSWQDLKD+MRQAGEVTYADAHK R NEGVIEF SYSDMKRAL+KLDGTE+NGR IRL+E
Sbjct: 121 CSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIE 180
Query: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
DKP + RRSYS SRS SRSR RSR SR RS S+SRSRS S SRSRS+SRS
Sbjct: 181 DKPRTSHRRSYSGSRSRSRSRRRSR-SRSRRS---------SRSRSRSISKSRSRSRSRS 230
Query: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
+ +SRSRSK KSRS SK K +S S SRS+SKD+ E+ + + +SRSP +
Sbjct: 231 KGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEK------SRSRSRSRSPKEN 284
Query: 295 KS---KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351
KSKSRSRSQ R S+ RS +++ SRSRS+ S+SRSRSRS S+
Sbjct: 285 GKGDIKSKSRSRSQSRS-NSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
Query: 352 D 352
D
Sbjct: 344 D 344
Score = 127 bits (319), Expect = 2e-29
Identities = 123/391 (31%), Positives = 177/391 (45%), Gaps = 52/391 (13%)
Query: 105 RLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTE 164
R+ + LS +D++ + G + D G G +EF D A+ +L+G E
Sbjct: 3 RVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGY---GFVEFEDSRDADDAVYELNGKE 59
Query: 165 VNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRS 224
+ G ++ +VE H+R R R SRSG S ++ R +
Sbjct: 60 LCGERV-IVE----------------HARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKY 102
Query: 225 GSRSRSKSRSRSQS-RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
G R++ R ++ SR + + ++ A K R+ N+ V
Sbjct: 103 GPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERT------------NEGV 150
Query: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEE-EKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342
+ +S S + + R + E + S RS S +SRSR RS+ SR
Sbjct: 151 IEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRR 210
Query: 343 RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
SRSRS+S K + R RSR + RSRSRS+ + R SK K K +DR
Sbjct: 211 SSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSR--------------SKSKSKPKSDRG 256
Query: 403 QSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRS 462
S S SRS SK+ E+ KS S R R EN + +++SRSRS S+S LP S++
Sbjct: 257 -SHSHSRSRSKD-EYEKSRSRSR-SRSPKENGKGDIKSKSRSRSQSRSNSPLPVPP-SKA 312
Query: 463 KSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
+S S R+ SRSRS SRS SRSRSRS SR
Sbjct: 313 RSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
Score = 54.3 bits (129), Expect = 2e-07
Identities = 53/164 (32%), Positives = 77/164 (46%), Gaps = 12/164 (7%)
Query: 334 SRSKGGSRSRSRSRSKSKDKRKGRKRSR---EESRSRSRSRSKSERSRKRGSKRDSKAGS 390
SRS GG S R+ + K R R E SR + + R+ G + A +
Sbjct: 84 SRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEV--TYADA 141
Query: 391 SKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKS 450
K++ E +S S + R K + ++ GR + + RS S S+S
Sbjct: 142 HKERTNEGVIEFRSYSDMK-----RALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRS 196
Query: 451 KPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
+ SRSRS+ +S++RSRS S+SRS SRS RS+ RS SRS
Sbjct: 197 RSRSRRRSRSRSRRSSRSRSRSISKSRSRSRS--RSKGRSRSRS 238
>gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 297 bits (761), Expect = 1e-80
Identities = 168/276 (60%), Positives = 202/276 (73%), Gaps = 18/276 (6%)
Query: 3 RVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCG 62
RV+IGRL+ ARE+DVERFFKGYG+I ++DLK G+GFVEF+D RDADDAVYEL+GK+LC
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
Query: 63 ERVIVEHARGPRRDGSYGSGRSGYGYRRSGRD-----KYGPPTRTEYRLIVENLSSRCSW 117
ERV +EHAR R G GR Y R S R + PP RTE RLIVENLSSR SW
Sbjct: 65 ERVTIEHARARSRGGR---GRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSW 121
Query: 118 QDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKP 177
QDLKD+MRQAGEVT+ADAH+ + NEGV+EF SY D+K A+EKL G E+NGRKI+L+E
Sbjct: 122 QDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE--- 178
Query: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGS-SKSSHSKSRSRSRSGSRSRSKSRSRS 236
GS+R SRS SRSRSR+R S +SRSRS S S+ S+S+SRSRSRS SRS+S+S SRS
Sbjct: 179 GSKR-----HSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRS 233
Query: 237 QSRSRSKKEKSRSPSKE-KSRSRSHSAGKSRSKSKD 271
+S+K S S SK S R S +SRS+S D
Sbjct: 234 PVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
Score = 74.3 bits (181), Expect = 2e-13
Identities = 75/280 (26%), Positives = 118/280 (42%), Gaps = 47/280 (16%)
Query: 105 RLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTE 164
R+ + L+ +D++ + + G + D +G G +EF D A+ +LDG E
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGF---GFVEFEDPRDADDAVYELDGKE 61
Query: 165 VNGRKIRLVEDKP---GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSG------SSKSSH 215
+ ++ + + G R R YS S R R+ R++ R+ + SS+ S
Sbjct: 62 LCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSW 121
Query: 216 SKSRSRSRSGSRSRSKSRSR-----------------------SQSRSRSKKEKSRSPSK 252
+ R R S +K K SK
Sbjct: 122 QDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSK 181
Query: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEE 312
SRSRS S ++RS S+ ++ + ++ + + +SRS SR +SKS+S SRS + +
Sbjct: 182 RHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPE-KSQ 240
Query: 313 KRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD 352
KRGS SR +S RQ RSRSRSRS+S D
Sbjct: 241 KRGSSSRSKSPASVDRQ-----------RSRSRSRSRSVD 269
Score = 60.8 bits (146), Expect = 3e-09
Identities = 75/246 (30%), Positives = 107/246 (43%), Gaps = 52/246 (21%)
Query: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS-KSRSRSQERRVEE 311
E +R+RS G+ R + D+ + ND P R+ +R ++ SR Q+ +
Sbjct: 70 EHARARSRG-GRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFM 128
Query: 312 EKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS-KSKDKRKGR--KRSREESRSRS 368
+ G V+ + L + S G ++ S K + RK + + S+ SRSRS
Sbjct: 129 RQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRS 188
Query: 369 RSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGR 428
RSRS++ RS SRS SRS S+ R KS S R
Sbjct: 189 RSRSRT--------------------------RSSSRSRSRSRSRSR---KSYSRSR--- 216
Query: 429 GESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRS 488
+ +RSRS+S S S+ +P +S+ R S SRSKS AS RSRS
Sbjct: 217 -------SRSRSRSRSKSRSVSRSPVPEKSQKRGSS-----SRSKS---PASVDRQRSRS 261
Query: 489 RSHSRS 494
RS SRS
Sbjct: 262 RSRSRS 267
Score = 60.1 bits (144), Expect = 5e-09
Identities = 66/211 (31%), Positives = 91/211 (43%), Gaps = 47/211 (22%)
Query: 322 SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRG 381
S+ ++ +R+RSR G R R R S+ R R R R+ +R E R
Sbjct: 64 SERVTIEHARARSRG-GRGRGRYSDRFSSRRPRNDR---RNAPPVRTENRLIVENLSSRV 119
Query: 382 SKRDSK-----------AGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE 430
S +D K A + + K E S ++ + K + GR
Sbjct: 120 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIE-----KLSGKEINGRKI 174
Query: 431 SENAGTNQETRSRSRSNSKSKPNLPSESRSRS---KSASKTRSRSKSRSRSASRSPSRS- 486
G+ + +RSRSRS S+++ + S SRSRS KS S++RSRS+SRSRS SRS SRS
Sbjct: 175 KLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSP 234
Query: 487 -----------------------RSRSHSRS 494
RSRS SRS
Sbjct: 235 VPEKSQKRGSSSRSKSPASVDRQRSRSRSRS 265
>gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 297 bits (761), Expect = 1e-80
Identities = 168/276 (60%), Positives = 202/276 (73%), Gaps = 18/276 (6%)
Query: 3 RVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCG 62
RV+IGRL+ ARE+DVERFFKGYG+I ++DLK G+GFVEF+D RDADDAVYEL+GK+LC
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
Query: 63 ERVIVEHARGPRRDGSYGSGRSGYGYRRSGRD-----KYGPPTRTEYRLIVENLSSRCSW 117
ERV +EHAR R G GR Y R S R + PP RTE RLIVENLSSR SW
Sbjct: 65 ERVTIEHARARSRGGR---GRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSW 121
Query: 118 QDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKP 177
QDLKD+MRQAGEVT+ADAH+ + NEGV+EF SY D+K A+EKL G E+NGRKI+L+E
Sbjct: 122 QDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE--- 178
Query: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGS-SKSSHSKSRSRSRSGSRSRSKSRSRS 236
GS+R SRS SRSRSR+R S +SRSRS S S+ S+S+SRSRSRS SRS+S+S SRS
Sbjct: 179 GSKR-----HSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRS 233
Query: 237 QSRSRSKKEKSRSPSKE-KSRSRSHSAGKSRSKSKD 271
+S+K S S SK S R S +SRS+S D
Sbjct: 234 PVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
Score = 74.3 bits (181), Expect = 2e-13
Identities = 75/280 (26%), Positives = 118/280 (42%), Gaps = 47/280 (16%)
Query: 105 RLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTE 164
R+ + L+ +D++ + + G + D +G G +EF D A+ +LDG E
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGF---GFVEFEDPRDADDAVYELDGKE 61
Query: 165 VNGRKIRLVEDKP---GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSG------SSKSSH 215
+ ++ + + G R R YS S R R+ R++ R+ + SS+ S
Sbjct: 62 LCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSW 121
Query: 216 SKSRSRSRSGSRSRSKSRSR-----------------------SQSRSRSKKEKSRSPSK 252
+ R R S +K K SK
Sbjct: 122 QDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSK 181
Query: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEE 312
SRSRS S ++RS S+ ++ + ++ + + +SRS SR +SKS+S SRS + +
Sbjct: 182 RHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPE-KSQ 240
Query: 313 KRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD 352
KRGS SR +S RQ RSRSRSRS+S D
Sbjct: 241 KRGSSSRSKSPASVDRQ-----------RSRSRSRSRSVD 269
Score = 60.8 bits (146), Expect = 3e-09
Identities = 75/246 (30%), Positives = 107/246 (43%), Gaps = 52/246 (21%)
Query: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS-KSRSRSQERRVEE 311
E +R+RS G+ R + D+ + ND P R+ +R ++ SR Q+ +
Sbjct: 70 EHARARSRG-GRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFM 128
Query: 312 EKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS-KSKDKRKGR--KRSREESRSRS 368
+ G V+ + L + S G ++ S K + RK + + S+ SRSRS
Sbjct: 129 RQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRS 188
Query: 369 RSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGR 428
RSRS++ RS SRS SRS S+ R KS S R
Sbjct: 189 RSRSRT--------------------------RSSSRSRSRSRSRSR---KSYSRSR--- 216
Query: 429 GESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRS 488
+ +RSRS+S S S+ +P +S+ R S SRSKS AS RSRS
Sbjct: 217 -------SRSRSRSRSKSRSVSRSPVPEKSQKRGSS-----SRSKS---PASVDRQRSRS 261
Query: 489 RSHSRS 494
RS SRS
Sbjct: 262 RSRSRS 267
Score = 60.1 bits (144), Expect = 5e-09
Identities = 66/211 (31%), Positives = 91/211 (43%), Gaps = 47/211 (22%)
Query: 322 SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRG 381
S+ ++ +R+RSR G R R R S+ R R R R+ +R E R
Sbjct: 64 SERVTIEHARARSRG-GRGRGRYSDRFSSRRPRNDR---RNAPPVRTENRLIVENLSSRV 119
Query: 382 SKRDSK-----------AGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE 430
S +D K A + + K E S ++ + K + GR
Sbjct: 120 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIE-----KLSGKEINGRKI 174
Query: 431 SENAGTNQETRSRSRSNSKSKPNLPSESRSRS---KSASKTRSRSKSRSRSASRSPSRS- 486
G+ + +RSRSRS S+++ + S SRSRS KS S++RSRS+SRSRS SRS SRS
Sbjct: 175 KLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSP 234
Query: 487 -----------------------RSRSHSRS 494
RSRS SRS
Sbjct: 235 VPEKSQKRGSSSRSKSPASVDRQRSRSRSRS 265
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 178 bits (451), Expect = 1e-44
Identities = 131/380 (34%), Positives = 198/380 (52%), Gaps = 53/380 (13%)
Query: 163 TEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRS 222
TE++ R ++ R +S+S+SRS RSRS S+ SR RS S K +HS++RSR+
Sbjct: 260 TEMSSR-VKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRT 318
Query: 223 RSG--------SRSRSKSRSRSQSRSRSKKEK-----SRSPSKEKSRSRSHSAGKSRSKS 269
R G S+SRS S+ +SQ++SR+ + SR+PSKE+S S S S+ K R
Sbjct: 319 RKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHR 378
Query: 270 KDQAEEKIQNNDNVGKP-------KSRSPSRHKSKSKSRS----RSQERRVEEEKRGSVS 318
+ K G P +SRSP++ + +S+SRS R + R K S
Sbjct: 379 GSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCS 438
Query: 319 RGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRS------------ 366
R RS K+ +SRSRS +K SRSRS +K++D+ + R S+E S
Sbjct: 439 RSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHR 498
Query: 367 RSRSRSKSER---SRKRGSKRDSKAGSSKKKKKE---------DTDRSQSRSPSRSVSKE 414
RSRS SK + SR +RD + S K+++ + DRSQSRSP S+E
Sbjct: 499 RSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSP----SEE 554
Query: 415 REHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKS 474
REH +S S +E + + + R +SRS+S+ + + S S ++ S+ R+ SK
Sbjct: 555 REHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKE 614
Query: 475 RSRSASRSPSRSRSRSHSRS 494
++ S SR+PS+ + S SR+
Sbjct: 615 KAHSRSRTPSKEGNHSQSRT 634
Score = 149 bits (377), Expect = 4e-36
Identities = 114/340 (33%), Positives = 175/340 (51%), Gaps = 37/340 (10%)
Query: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRS 236
P RS S S + R SRSR K+R RS S ++ RSRSRS +++R SRSRS
Sbjct: 383 PRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRS 442
Query: 237 QSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP-------KSR 289
++R + +SRSP+K + SRS S K+R +S+ ++ K +++ +G P +SR
Sbjct: 443 PYKARDRS-RSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSR 501
Query: 290 SPS------------------RHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSR 331
SPS R +S SK R R Q R +E+ S SR S+E+ RQSR
Sbjct: 502 SPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSR 561
Query: 332 SRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSK-SERSRKRGSKRDSKAGS 390
S S+ + R R RS SK +++R+ R S E SRSRS +K S SR R S ++
Sbjct: 562 SPSKER--DRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSR 619
Query: 391 SKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKS 450
S+ KE + S SR+ SKE + ++S + + + + T + S++R+ SK+
Sbjct: 620 SRTPSKEG-----NHSQSRTSSKESDPSQSTVPRSP---DWKRSPTRTSSLSQNRTPSKT 671
Query: 451 KPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRS 490
+ PS S ++ S+ S++ + + A+ RS S S
Sbjct: 672 SSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSS 711
Score = 139 bits (350), Expect = 6e-33
Identities = 113/368 (30%), Positives = 187/368 (50%), Gaps = 52/368 (14%)
Query: 179 SRRRRSYSRSRSHSRSRSR-------SRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSK 231
S R S SR RS +R+ SR S+ S+ S R + +HS+ R+ R GSRS +
Sbjct: 75 SNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKR 134
Query: 232 SRSRSQSRSRSKKE--------KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQN---- 279
S SR+ + R + + R+P+ ++ SR S G+ R+ ++++++ + +N
Sbjct: 135 SPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKK 194
Query: 280 ------NDNVGKP----------KSRSPSRHKSKSKSR--SRSQERRVEE---------E 312
+G+ K ++P+ SK KS S S R+V+ E
Sbjct: 195 SYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSRE 254
Query: 313 KRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS--RSRSKSKDKRKGRKRSREESRSRSRS 370
K S + S+ KS Q+ +RSR + S+SRS RSRS S+ + R RS R+ SR+
Sbjct: 255 KSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRA 314
Query: 371 RSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS----QSRSPSRSVSKEREHAKSESSQRE 426
RS++ + R S++ S K K ++ R+ +S + SR+ SKER H+ S SS +E
Sbjct: 315 RSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKE 374
Query: 427 GRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRS 486
++ + RS+S S +K + + S S ++++ S++RS K+R RS SRSP+++
Sbjct: 375 RDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKA 434
Query: 487 RSRSHSRS 494
R S SRS
Sbjct: 435 RDCSRSRS 442
Score = 103 bits (257), Expect = 4e-22
Identities = 105/385 (27%), Positives = 175/385 (45%), Gaps = 57/385 (14%)
Query: 151 SDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGS 210
S KR+ + +G + + KP + + + S + + S ++ SR S S
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
Query: 211 SKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSK 270
SKS+ S S R+ S +R SRSR +S K+R+PS+ + +R+ A SK+
Sbjct: 62 SKSTKSTSTKRAPS---NRPSSRSRVRS-------KARTPSRVSTDTRTSKA----SKAS 107
Query: 271 DQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQER-RVEEEKRGSVSRGRSQEKSLRQ 329
D + + + G+ R SR +S SR+ + R R + G SR R+ + +Q
Sbjct: 108 DVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRT--PTSQQ 165
Query: 330 SRSRSRSKGGSRSRSRSRSKSKDKRKGRK-----------RSREESRSRSRSRSKSERSR 378
SR +S G R+ +R RS S+ + +K RS E + + S ++ ++
Sbjct: 166 KGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGI 225
Query: 379 KRGSKRDSKAGSSKKKKK-----------------EDTDRSQSRSPSRSVSKEREHAKSE 421
K D+ + SS +K K E + R +S + + + S+ + H++S
Sbjct: 226 PSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSR 285
Query: 422 SSQREGRGESENAGT----------NQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSR 471
S +R G + + + RSR+R S+ S+SRS SK S+ +SR
Sbjct: 286 SPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSR 345
Query: 472 SKSRSRSA--SRSPSRSRSRSHSRS 494
+ R RS SR+PS+ RS SHSRS
Sbjct: 346 TPRRGRSHNWSRNPSKERSHSHSRS 370
Score = 90.9 bits (224), Expect = 2e-18
Identities = 72/231 (31%), Positives = 123/231 (53%), Gaps = 22/231 (9%)
Query: 164 EVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRS--- 220
E + R+ R + R+ RS S+ R H RSRS S+ ++ +SRS + + S+SRS
Sbjct: 494 ERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSE 553
Query: 221 -----RSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEE 275
+SRS S+ R + R RS S+ R +++ SRS S+E+ SRS S K S+ +A
Sbjct: 554 EREHRQSRSPSKERDRRRWRSPSKERERRQ-SRSSSEERDHSRSRSPNKQSGYSRPRASS 612
Query: 276 KIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSR 335
K + + +SR+PS+ + S+SR+ S+E + + +V R ++S +R+ S
Sbjct: 613 KEKAHS-----RSRTPSKEGNHSQSRTSSKE---SDPSQSTVPRSPDWKRS--PTRTSSL 662
Query: 336 SKGGSRSRSRSRSKSKDKRKGRKRSREESR---SRSRSRSKSERSRKRGSK 383
S+ + S++ S S S G+ S+++S+ + S++ ERS SK
Sbjct: 663 SQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSK 713
>gi|5902076 splicing factor, arginine/serine-rich 1 isoform 1 [Homo
sapiens]
Length = 248
Score = 172 bits (435), Expect = 8e-43
Identities = 112/241 (46%), Positives = 140/241 (58%), Gaps = 20/241 (8%)
Query: 3 RVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYG-----FVEFDDLRDADDAVYELNG 57
R+Y+G L R +D+E F YG I ++DLKN G FVEF+D RDA+DAVY +G
Sbjct: 17 RIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDG 76
Query: 58 KDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTR-TEYRLIVENLSSRCS 116
D G R+ VE R R G G G G G + R +YGPP+R +E R++V L S
Sbjct: 77 YDYDGYRLRVEFPRSGRGTGRGGGGGGGGG---APRGRYGPPSRRSENRVVVSGLPPSGS 133
Query: 117 WQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRK-----IR 171
WQDLKD+MR+AG+V YAD + R GV+EFV DM A+ KLD T+ + IR
Sbjct: 134 WQDLKDHMREAGDVCYADVY--RDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIR 191
Query: 172 LVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSK 231
+ D P R SY RSRS SRSRSRSR SRSRS S + S R R SRSRS+
Sbjct: 192 VKVDGP---RSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRH-SRSRSR 247
Query: 232 S 232
+
Sbjct: 248 T 248
Score = 48.9 bits (115), Expect = 1e-05
Identities = 73/283 (25%), Positives = 104/283 (36%), Gaps = 50/283 (17%)
Query: 97 GPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRA 156
GP + R+ V NL +D++D + G + D K R+ FV + D + A
Sbjct: 9 GPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDL-KNRRGGPPFAFVEFEDPRDA 67
Query: 157 LEKL---DGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKS 213
+ + DG + +G ++R+ + G + R G
Sbjct: 68 EDAVYGRDGYDYDGYRLRVEFPRSG------------------------RGTGRGGGGGG 103
Query: 214 SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQA 273
R R SR RS++R PS + H D
Sbjct: 104 GGGAPRGRYGPPSR-------RSENRV---VVSGLPPSGSWQDLKDHMREAGDVCYADVY 153
Query: 274 EEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQER---RVEEEKRGSVSRGRSQEKSLRQS 330
+ + V K R +K RS E RV+ + S S GRS
Sbjct: 154 RDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRS-------- 205
Query: 331 RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESR-SRSRSRS 372
RSRSRS+ SRSRS SRS+S R+ R R R SRSRSR+
Sbjct: 206 RSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT 248
Score = 48.5 bits (114), Expect = 1e-05
Identities = 48/155 (30%), Positives = 66/155 (42%), Gaps = 33/155 (21%)
Query: 373 KSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSR------SPSRSVSKEREHAKSESS--- 423
+S R RG G+ + + + RS++R PS S ++H +
Sbjct: 90 RSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCY 149
Query: 424 ---QREGRGESENAGTNQETRS-RSRSNSKSK---------------PNLPSESRSRSKS 464
R+G G E T + R N+K + P PS RSRS+S
Sbjct: 150 ADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRS 209
Query: 465 ASKTRSRSKSRSRSASRSPSRSR-----SRSHSRS 494
S++RSRS+S SRS S SP RSR S HSRS
Sbjct: 210 RSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRS 244
Score = 43.1 bits (100), Expect = 6e-04
Identities = 24/48 (50%), Positives = 27/48 (56%)
Query: 333 RSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKR 380
RS S G SRSRSRSRS+S+ + R RS RSR R SR R
Sbjct: 198 RSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSR 245
Score = 39.7 bits (91), Expect = 0.006
Identities = 30/61 (49%), Positives = 32/61 (52%), Gaps = 11/61 (18%)
Query: 335 RSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKK 394
RS RSRSRSRS RSR SRS SRSRS S R R RGS R S S +
Sbjct: 198 RSPSYGRSRSRSRS----------RSRSRSRSNSRSRSYSPR-RSRGSPRYSPRHSRSRS 246
Query: 395 K 395
+
Sbjct: 247 R 247
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 150 bits (379), Expect = 3e-36
Identities = 134/360 (37%), Positives = 187/360 (51%), Gaps = 45/360 (12%)
Query: 163 TEVNGRKIRLVEDKPGSRRRRSYSRSRSHS-----RSRSRSRHSR-KSRSRSGSSKSSHS 216
T GR K G R RS RS S RSRS R R +S R G S+S ++
Sbjct: 489 TAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNT 548
Query: 217 KSRSRSRSGSRSRSKSRS-----RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKD 271
+ R RSRS R RS SRS RS+SR+ +++ +SRS + + RSRS + + RS+S+
Sbjct: 549 QRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRT 608
Query: 272 QAEEKIQNNDNVGKPKSRSPSRHKSKS------KSRSRSQERRV-EEEKRGSVSRGRSQE 324
A G+ +SR+P+R +S++ +SRSRS RR R RGRS+
Sbjct: 609 PARR--------GRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRS 660
Query: 325 KS-LRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRS--KSERSRKRG 381
++ R+ RSRSR+ RSRSR+ + R+GR RSR R RSRSRS + RS R
Sbjct: 661 RTPARRGRSRSRTPARRSGRSRSRTPA---RRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
Query: 382 SKRDSKAG-SSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQET 440
+R ++G SS++K K T + +SRS S E KS S R R S +
Sbjct: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNS-----SPEMKKSRISSRRSRSLSSPRSKAKSR 772
Query: 441 RSRSRSNSKSKPNLPSESRS---RSKSAS---KTRSRS-KSRSRSASRSPSRSRSRSHSR 493
S RS S S P +S++ RS+S S K +SR+ RSRS+S P + +S++ SR
Sbjct: 773 LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR 832
Score = 145 bits (367), Expect = 6e-35
Identities = 130/362 (35%), Positives = 182/362 (50%), Gaps = 55/362 (15%)
Query: 177 PGSRRRRSYS---RSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGS---RSRS 230
PGS R S S ++RSH R++ HS R G S+S + R RSRS + R S
Sbjct: 447 PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHS 506
Query: 231 KSRSRSQSRSRSKKE--KSRSPSKEKSRSRS-HSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
+SRS RSRS + +SRSP + + RSRS G SRS++ + + G+
Sbjct: 507 RSRSPQWRRSRSAQRWGRSRSPQR-RGRSRSPQRPGWSRSRNTQRRGRS--RSARRGRSH 563
Query: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS---KGGSRSRS 344
SRSP+ ++ +SRSR+ RR R + +R RS+ ++ + RSRSR+ +G SRSR+
Sbjct: 564 SRSPA---TRGRSRSRTPARRGRSRSR-TPARRRSRSRTPTRRRSRSRTPARRGRSRSRT 619
Query: 345 --------------RSRSKSKDKRKGRKRSREES-RSRSRSRSKSERSRKRGSKRDSKAG 389
RSRS+S +R GR RSR + R RSRSR+ + R R R ++G
Sbjct: 620 PARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSG 679
Query: 390 SSKKKKKEDTDRSQSRSPSRSVSKERE-----HAKSESSQREGRGESENAGTNQETRSRS 444
S+ + RS+SR+P R S+ R + S + QR GR S + N+ S+
Sbjct: 680 RSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQR 739
Query: 445 RSNSKSKPNLPSE--SRSRSKSASKTRSRSKSR---SRSASRS-----------PSRSRS 488
RS S S P + S RS+S S RS++KSR RS S S P RSRS
Sbjct: 740 RSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRS 799
Query: 489 RS 490
S
Sbjct: 800 GS 801
Score = 142 bits (359), Expect = 5e-34
Identities = 123/327 (37%), Positives = 174/327 (53%), Gaps = 44/327 (13%)
Query: 176 KPG-SRRRRSYSRSRSHSRSRSRSRHSR----KSRSRSGS-SKSSHSKSRSRSRSGSRSR 229
+PG SR R + R RS S R RS HSR + RSRS + ++ S+SR+ +R SRSR
Sbjct: 539 RPGWSRSRNTQRRGRSRSARRGRS-HSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSR 597
Query: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
+ +R RS+SR+ +++ +SRS + + RSR+ S + RS+S+ A G+ +SR
Sbjct: 598 TPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRS-------GRSRSR 650
Query: 290 SPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS---KGGSRSRSRS 346
+P+R + +SRSR+ RR R RS+ + R RSRSR+ +G SRSR+
Sbjct: 651 TPAR---RGRSRSRTPARR---------GRSRSRTPARRSGRSRSRTPARRGRSRSRTPR 698
Query: 347 RSKSKDK---RKGRKRSREESRSRSRSRSKSERSRK-RGSKRDSKAGSSKKKKKEDTDRS 402
R +S+ + R+GR SR R R RS S SER K R S+R S++ SS + KK R
Sbjct: 699 RGRSRSRSLVRRGRSHSRTPQR-RGRSGSSSERKNKSRTSQRRSRSNSSPEMKK---SRI 754
Query: 403 QSRSPSRSVSKEREHAKSESSQREG-RGESENAGTNQETRSRSRSNSKSKPNL-----PS 456
SR SRS+S R AKS S R G S +T R + S+P P
Sbjct: 755 SSRR-SRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR 813
Query: 457 ESRSRSKSASKTRSRSKSRSRSASRSP 483
SRS S K +S++ SR +S SP
Sbjct: 814 RSRSSSSPPPKQKSKTPSRQSHSSSSP 840
Score = 137 bits (344), Expect = 3e-32
Identities = 126/361 (34%), Positives = 180/361 (49%), Gaps = 51/361 (14%)
Query: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238
+RR RS SR+ + RSRSR+ R+SRSR+ ++ S+SR+ +R SR+RS R RS+S
Sbjct: 579 ARRGRSRSRTPARRRSRSRTPTRRRSRSRT-PARRGRSRSRTPARRRSRTRSPVRRRSRS 637
Query: 239 RS---RSKKEKSRSPSKEKSRSRSHS-AGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
RS RS + +SR+P++ + RSRS + A + RS+S+ A ++ + RS SR
Sbjct: 638 RSPARRSGRSRSRTPAR-RGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRT 696
Query: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR 354
+ +SRSRS RR R RGRS S R+++SR+ + RSRS S + K R
Sbjct: 697 PRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQR---RSRSNSSPEMKKSR 753
Query: 355 KGRKRSREESRSRSRSRSK-SERSRKRGSK-----------RDSKAGSSKKKKKEDTDRS 402
+RSR S RS+++S+ S R GS R S++GSS+ K K T
Sbjct: 754 ISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR 813
Query: 403 QSRS------------PSR-SVSKEREHAKSESSQREGRGESENAGTNQET---RSRSRS 446
+SRS PSR S S H K +S +G + N+++ + RS
Sbjct: 814 RSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCF 873
Query: 447 NSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRS-------------RSRSHSR 493
S P L S + SR + + R KS S +SPSRS R RSHS
Sbjct: 874 ESSPDPELKSRTPSRHSCSGSSPPRVKS-STPPRQSPSRSSSPQPKVKAIISPRQRSHSG 932
Query: 494 S 494
S
Sbjct: 933 S 933
Score = 136 bits (343), Expect = 4e-32
Identities = 113/348 (32%), Positives = 166/348 (47%), Gaps = 33/348 (9%)
Query: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227
RK RL SRR RS S S +RSR+ RH R+S S S + S+S R RS S
Sbjct: 1699 RKARL------SRRSRSASSS-PETRSRTPPRH-RRSPSVSSPEPAEKSRSSRRRRSASS 1750
Query: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
R+K+ SR R RS K R + +SRSR +R + + + + + +
Sbjct: 1751 PRTKTTSR---RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSR 1807
Query: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
SR R + S SRS R+ RGRS+ + RSRSR+ RSRSR
Sbjct: 1808 SRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSR 1867
Query: 348 SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
+ R+ R R+ SR RSRSR+ S SR+R R S + + R +SRS
Sbjct: 1868 ASPATHRRSRSRTPLISRRRSRSRT-SPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSR 1926
Query: 408 SRSVSKEREHAKSESSQREGRGESENAGTNQET---------RSRSRSN------SKSKP 452
+ V++ R +++ +++R R + + RSRSR++ S+S+
Sbjct: 1927 TPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRT 1986
Query: 453 NLPSESRSRSKSASKTRSRSKSRS------RSASRSPSRSRSRSHSRS 494
+ + RSRS+++ TR RS+SR+ RS SR+P R RS SR+
Sbjct: 1987 SPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRT 2034
Score = 135 bits (339), Expect = 1e-31
Identities = 117/330 (35%), Positives = 168/330 (50%), Gaps = 36/330 (10%)
Query: 176 KPGSRRRRSYS-RSRSHSRSRSRSRHSR----KSRSRSGSSKS-SHSKSRSRSRSGSRSR 229
K SRR RS S + R RSRSRSR + + R RSGSS+S S + RSRSRS R
Sbjct: 1754 KTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRR 1813
Query: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
+ S SRS +++E SR+ S+ + R RS + SR +S+ + P R
Sbjct: 1814 RRGGSGYHSRSPARQESSRTSSRRR-RGRSRTPPTSRKRSRSRTSPA---------PWKR 1863
Query: 290 SPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGG-SRSRSRSRS 348
S SR + RSRS + +SR RS+ ++ SR RSRS+ +R RSRSR+
Sbjct: 1864 SRSRASPATHRRSRS--------RTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA 1915
Query: 349 KSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPS 408
+R+ R R+ +R RSRSR+ + R R R S+ + + R +SRS +
Sbjct: 1916 SPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR-SRTPPVTRRRSRSRTPPVTRRRSRSRT 1974
Query: 409 RSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKT 468
+++ R +++ R + T+ TR RSR S++ P SRSR+ A +
Sbjct: 1975 SPITRRRSRSRTSPVTRR----RSRSRTSPVTRRRSR--SRTSPVTRRRSRSRTPPAIRR 2028
Query: 469 RSRSKS----RSRSASRSPSRSRSRSHSRS 494
RSRS++ R RS SRSP R RS SR+
Sbjct: 2029 RSRSRTPLLPRKRSRSRSPLAIRRRSRSRT 2058
Score = 129 bits (325), Expect = 5e-30
Identities = 115/368 (31%), Positives = 172/368 (46%), Gaps = 54/368 (14%)
Query: 174 EDKPGSRRRRSYSRS--------RSHSRSRS---------RSRHSRKSRSRSGSSKS--- 213
E P SR R SRS R+ R RS ++R SR+SRS S S ++
Sbjct: 1660 EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719
Query: 214 -------SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSR 266
S S S SRS + RS S R+++ + RSPS + +SR
Sbjct: 1720 TPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPS-----PKPRGLQRSR 1774
Query: 267 SKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSR------------SRSQERRVEEEKR 314
S+S+ + + D G +S S R +S+S+SR SRS R+
Sbjct: 1775 SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTS 1834
Query: 315 GSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKS 374
RGRS+ + RSRSR+ RSRSR+ R+ R R+ SR RSRSR+ S
Sbjct: 1835 SRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRT-S 1893
Query: 375 ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENA 434
SR+R R S + + R +SRS + V++ R +++ +++R R +
Sbjct: 1894 PVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPV 1953
Query: 435 GTNQETRSR----SRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSR--- 487
T + +RSR +R S+S+ + + RSRS+++ TR RS+SR+ +R SRSR
Sbjct: 1954 -TRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSP 2012
Query: 488 -SRSHSRS 494
+R SRS
Sbjct: 2013 VTRRRSRS 2020
Score = 128 bits (321), Expect = 1e-29
Identities = 108/350 (30%), Positives = 172/350 (49%), Gaps = 29/350 (8%)
Query: 155 RALEKLDGTEVNGRKIRLVEDKPGSRRR-RSYSRSRSHSRSRSRSRHSRKSRSRSGSSKS 213
R+ + + T R+ R + SRRR RS SRSR R R S + +S +R SS++
Sbjct: 1774 RSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRT 1833
Query: 214 SHSKSRSRSRSGSRSRSKSRSRS------QSRSRS-----KKEKSRSPSKEKSRSRSHSA 262
S + R RSR+ SR +SRSR+ +SRSR+ ++ +SR+P + RSRS ++
Sbjct: 1834 SSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTS 1893
Query: 263 GKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGS-----V 317
SR +S+ + + + + P SR SR ++ +R RS+ R +R V
Sbjct: 1894 PVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPV 1953
Query: 318 SRGRSQEKS--LRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSE 375
+R RS+ ++ + + RSRSR+ +R RSRSR+ +R+ R R+ +R RSRSR+
Sbjct: 1954 TRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPV 2013
Query: 376 RSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAG 435
R+ S+ + + R +SRS S + R ++ + R RG+
Sbjct: 2014 TRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSR---TPRTARGKRSLTR 2070
Query: 436 TNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSR 485
+ R RS S S S RSRS + TR+ S SR+ + + SR
Sbjct: 2071 SPPAIRRRSASGS-------SSDRSRSATPPATRNHSGSRTPPVALNSSR 2113
Score = 126 bits (316), Expect = 5e-29
Identities = 104/332 (31%), Positives = 163/332 (49%), Gaps = 19/332 (5%)
Query: 175 DKPGSRRRR-----SYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR 229
+K + RRR S S SR RSRSRSR +R+ R SG S ++ S S R R
Sbjct: 1780 EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRR 1839
Query: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
+SR+ SR RS+ S +P K +SRSR+ A RS+S+ + ++ P SR
Sbjct: 1840 GRSRTPPTSRKRSRSRTSPAPWK-RSRSRASPATHRRSRSRTPLISRRRSRSRTS-PVSR 1897
Query: 290 SPSRHKS-----KSKSRSRSQERRVEEEKRGSVSRGRSQEKS-LRQSRSRSRSKGGSRSR 343
SR ++ +S+SR+ RR + V+R RS+ ++ + RSRSR+ +R R
Sbjct: 1898 RRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRR 1957
Query: 344 SRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQ 403
SRSR+ +R+ R R+ +R RSRSR+ R+ S+ + + R +
Sbjct: 1958 SRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRR 2017
Query: 404 SRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSK 463
SRS + + R +++ R+ + +RSR+ ++ K +L +RS
Sbjct: 2018 SRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSL-----TRSP 2072
Query: 464 SASKTRSRSKSRS-RSASRSPSRSRSRSHSRS 494
A + RS S S S RS S +P +R+ S SR+
Sbjct: 2073 PAIRRRSASGSSSDRSRSATPPATRNHSGSRT 2104
Score = 125 bits (315), Expect = 7e-29
Identities = 118/369 (31%), Positives = 175/369 (47%), Gaps = 47/369 (12%)
Query: 149 SYSDMKRALEKLDGTEVNGRKIRLVEDKP-GSRRRRSYSRSRSHSRSRSRSRHS------ 201
S S +R T+ R+ R KP G +R RS SR +R R R
Sbjct: 1739 SRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTS 1798
Query: 202 -RKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR-SQSRSRSKKEKSRSP--SKEKSRS 257
R+ RSRS S R R SG SRS +R S++ SR ++ +SR+P S+++SRS
Sbjct: 1799 RRRQRSRS----RSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRS 1854
Query: 258 RSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSV 317
R+ A RS+S+ SP+ H+ +S+SR+ RR + V
Sbjct: 1855 RTSPAPWKRSRSR------------------ASPATHR-RSRSRTPLISRRRSRSRTSPV 1895
Query: 318 SRGRSQEK-SLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSER 376
SR RS+ + S+ + RSRSR+ SR RSRSR+ +R+ R R+ +R RSRSR+
Sbjct: 1896 SRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRT-PTTRRRSRSRTPPVT 1954
Query: 377 SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGT 436
R+ S+ + + R +SRS + V++ R +++ R + T
Sbjct: 1955 RRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVT 2014
Query: 437 NQETRSRS----RSNSKSKPNLPSESRSRSKSASKTRSRSKSRS-------RSASRSPSR 485
+ +RSR+ R S+S+ L RSRS+S R RS+SR+ RS +RSP
Sbjct: 2015 RRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPA 2074
Query: 486 SRSRSHSRS 494
R RS S S
Sbjct: 2075 IRRRSASGS 2083
Score = 120 bits (302), Expect = 2e-27
Identities = 115/350 (32%), Positives = 158/350 (45%), Gaps = 55/350 (15%)
Query: 186 SRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSR---SRSRSGSRSRSKSRSRSQSRSRS 242
S S S S++++R + RSRSGSS SKSR RSRSGS K + R+ R++S
Sbjct: 1557 SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS 1616
Query: 243 KKEKSRSPSKEKSR-----SRSHSAGKSRSKS---------------KDQAEEKIQNNDN 282
+ S P R SRS S+ K R S K + + +
Sbjct: 1617 GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSP 1676
Query: 283 VGKPKSRSPSRHKSKSKS-----------RSRSQERRVEEEKRGSVSRGRSQEKSLRQSR 331
K KSR+P R +S S RSRS E R RS S +
Sbjct: 1677 EPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPA 1736
Query: 332 SRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSS 391
+SRS RS S R+K+ +R GR S + R RSRS+S R + R ++R ++GSS
Sbjct: 1737 EKSRSSRRRRSASSPRTKTTSRR-GRSPS-PKPRGLQRSRSRSRREKTRTTRRRDRSGSS 1794
Query: 392 KKKKKEDTDRSQSRSPSRS-VSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKS 450
+ T R + RS SRS V++ R S+ R ES + R R S++
Sbjct: 1795 -----QSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSR-----RRRGRSRT 1844
Query: 451 KPNLPSESRSRSKSASKTRSRSKSRS------RSASRSPSRSRSRSHSRS 494
P S RSRS+++ RS+SR+ RS SR+P SR RS SR+
Sbjct: 1845 PPT--SRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRT 1892
Score = 119 bits (297), Expect = 8e-27
Identities = 112/351 (31%), Positives = 155/351 (44%), Gaps = 45/351 (12%)
Query: 187 RSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRS-----RSRSGSRSRSKSRSRSQSRSR 241
RS S S S+++ R RS S S S+S RSRSGS K + R+ R++
Sbjct: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQ 1615
Query: 242 SKKE-----KSRSPSKEKSRSRSHSAGKSRSKS---------------KDQAEEKIQNND 281
S + K+ +P RSRS S+ K R S K + + +
Sbjct: 1616 SGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSS 1675
Query: 282 NVGKPKSRSPSRHKSKSKS-----------RSRSQERRVEEEKRGSVSRGRSQEKSLRQS 330
K KSR+P R +S S RSRS E R RS S +
Sbjct: 1676 PEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEP 1735
Query: 331 RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGS 390
+SRS RS S R+K+ R+GR S + R RSRS+S R + R ++R ++GS
Sbjct: 1736 AEKSRSSRRRRSASSPRTKT-TSRRGRSPS-PKPRGLQRSRSRSRREKTRTTRRRDRSGS 1793
Query: 391 SKK-KKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQET--RSRSRSN 447
S+ ++ RS+SR R H++S + Q R S T SR RS
Sbjct: 1794 SQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSR 1853
Query: 448 SKSKPNLPSESRSRSKSASKTRSRSK----SRSRSASRSPSRSRSRSHSRS 494
S++ P SRSR+ A+ RSRS+ SR RS SR+ SR RS SR+
Sbjct: 1854 SRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRT 1904
Score = 117 bits (292), Expect = 3e-26
Identities = 109/361 (30%), Positives = 177/361 (49%), Gaps = 53/361 (14%)
Query: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKS--------RSRSRSGSRSRS 230
S+ R S RSRS S + + R++SGS S K+ RSRS S S+ R
Sbjct: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG 1646
Query: 231 KSRSRSQS---------RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKS-----KDQAEEK 276
S S S +SR+ + SRS + K++SR+ +S S K + +
Sbjct: 1647 PSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRR 1706
Query: 277 IQNNDNVGKPKSRSPSRHKSK---------SKSRSRSQERRVEEEKRGSVSR-GRS---Q 323
++ + + +SR+P RH+ KSRS + R + + SR GRS +
Sbjct: 1707 SRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766
Query: 324 EKSLRQSRSRSRSKGGSRSRSRSRS-KSKDKRKGRKRSREESRSRSRSRSKSERSRKRGS 382
+ L++SRSRSR + +R R RS S+ + R+RS RSRS+ R R+ GS
Sbjct: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRS--------RSRSRVTRRRRGGS 1818
Query: 383 KRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRS 442
S++ + ++ + + R + RS + S++R +++ + + + T++ +RS
Sbjct: 1819 GYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS 1878
Query: 443 R----SRSNSKSKPNLPSESRSRSK-SASKTRSRSK----SRSRSASRSPSRSRSRSHSR 493
R SR S+S+ + S RSRS+ S ++ RSRS+ SR RS SR+P +R RS SR
Sbjct: 1879 RTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938
Query: 494 S 494
+
Sbjct: 1939 T 1939
Score = 113 bits (282), Expect = 5e-25
Identities = 104/333 (31%), Positives = 151/333 (45%), Gaps = 32/333 (9%)
Query: 189 RSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRS--RSKSRSRSQSRSRSKKEK 246
RS S S S+ R S S S H +R GSRS K++SR+ R RS +
Sbjct: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS 1694
Query: 247 SRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP----KSRSPSRHKSKSKSRS 302
K + RS SA S +++ + + + + +V P KSRS R +S S R+
Sbjct: 1695 PELTRKARLSRRSRSASSS-PETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRT 1753
Query: 303 RSQERRVEE---EKRG-SVSRGRSQEKSLRQSRSRSRSKGGS-------RSRSRSRSKSK 351
++ RR + RG SR RS+ + R +R R RS RSRSRSR
Sbjct: 1754 KTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRV--- 1810
Query: 352 DKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV 411
R+ R S SRS +R S SR+R + + S K+ + + RS SR+
Sbjct: 1811 -TRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRAS 1869
Query: 412 SKEREHAKSESSQREGRGESENAGTNQETRSRSRSN-----SKSKPNLPSESRSRSKSAS 466
++S + R RSRSR++ S+S+ + S RSRS++
Sbjct: 1870 PATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPP 1929
Query: 467 KTRSRSKSRS-----RSASRSPSRSRSRSHSRS 494
TR RS+SR+ RS SR+P +R RS SR+
Sbjct: 1930 VTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT 1962
Score = 112 bits (280), Expect = 8e-25
Identities = 105/342 (30%), Positives = 165/342 (48%), Gaps = 48/342 (14%)
Query: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
D+ + +S S S + ++ SR S S +S S S S++
Sbjct: 402 DRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKN 461
Query: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
RS R++ K S +PS+ RSRS + K G+ +SR+P++
Sbjct: 462 RSHGRAKRDKSHSHTPSRRMGRSRSPATAKR------------------GRSRSRTPTK- 502
Query: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGG-SRSRS-RSRSKSKD 352
+ SRSRS + R R + GRS+ R+ RSRS + G SRSR+ + R +S+
Sbjct: 503 --RGHSRSRSPQWR---RSRSAQRWGRSRSPQ-RRGRSRSPQRPGWSRSRNTQRRGRSRS 556
Query: 353 KRKGRKRSREES---RSRSRSRSKSERSRKR-GSKRDSKAGSSKKKKKED-----TDRSQ 403
R+GR SR + RSRSR+ ++ RSR R ++R S++ + +++ RS+
Sbjct: 557 ARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSR 616
Query: 404 SRSPSRSVSKEREHAKSES-----SQREGRGESENAGTNQETRSRS---RSNSKSKPNLP 455
SR+P+R S+ R + S ++R GR S +RSR+ R S+S+
Sbjct: 617 SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPAR 676
Query: 456 SESRSRSKSASKTRSRSKSRSRSASRSPSRS---RSRSHSRS 494
RSRS++ ++ R RS+SR+ RS SRS R RSHSR+
Sbjct: 677 RSGRSRSRTPAR-RGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
Score = 112 bits (279), Expect = 1e-24
Identities = 139/497 (27%), Positives = 208/497 (41%), Gaps = 93/497 (18%)
Query: 78 SYGSGRSGYGYRRSGRDKYGPPTRTE-YRLIVENLSSRCSWQDLKDYMRQAGEVTYADAH 136
SY G S RR+ K P + Y L+ E+ SSR K ++ +++
Sbjct: 144 SYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESS 203
Query: 137 KGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRS 196
R+ K + +K +E +K + P S+R+ S + R SRS +
Sbjct: 204 SPRRER----------KKSSKKKKHRSESESKKRKHRSPTPKSKRK-SKDKKRKRSRSTT 252
Query: 197 RSRHSRKS-RSRSGSSKSSHSKSRSRSRSGS----------RSRSKSRSR---------- 235
+ SR++ RS S S SS SRSRSRS + RS S + R
Sbjct: 253 PAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSE 312
Query: 236 ----SQSRSRSKKEKSRSPS----------KEKSRSR-SHSAGKSRSKSKDQAEEKIQ-- 278
S R S + ++ PS KEKS +R S S +S + + A +
Sbjct: 313 PGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAE 372
Query: 279 --------------NNDNVGKPKSRSPSRHKSKSKS-----RSRSQERRVEEEKRGSVSR 319
+ + V P SP+R +S KS +S S E + VSR
Sbjct: 373 RHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSR 432
Query: 320 GRSQEK----------SLRQSRSRSRSKG---GSRSRSRSRSKSKDKRKGRKRS---REE 363
S S R+ S SK G R +S S + +R GR RS +
Sbjct: 433 HASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKR 492
Query: 364 SRSRSRSRSKSERSRKRGSK-RDSKAGSSKKKKKEDTDRSQSRSPSR---SVSKEREHAK 419
RSRSR+ +K SR R + R S++ + + R +SRSP R S S+ +
Sbjct: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRG 552
Query: 420 SESSQREGRGESENAGTNQETRSRSRS-NSKSKPNLPSESRSRSKSASKTRSRSKS---R 475
S R GR S + T +RSR+ + +S+ P+ RSRS++ ++ RSRS++ R
Sbjct: 553 RSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARR 612
Query: 476 SRSASRSPSRSRSRSHS 492
RS SR+P+R RSR+ S
Sbjct: 613 GRSRSRTPARRRSRTRS 629
Score = 109 bits (272), Expect = 7e-24
Identities = 122/406 (30%), Positives = 171/406 (42%), Gaps = 39/406 (9%)
Query: 112 SSRCSWQDLKDYM-RQAGEVTYADAHKG-RKNEGVIEFVSYSDMKRALEKLDGTEVNGRK 169
SS S ++KD + R + + + G R G S S ++ + T GR
Sbjct: 1419 SSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRS 1478
Query: 170 IRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR 229
+P + + RSRS S ++ R RSGS S K+ +R+ G RSR
Sbjct: 1479 ECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSR 1538
Query: 230 SKSRSRSQSR-SRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKS 288
S S + S S +E+S S S S++++ + + RS+S E V
Sbjct: 1539 SGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPE--------VDSKSR 1590
Query: 289 RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS 348
SP R +S S + + R + GS S + + R RSRS S+ R S
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650
Query: 349 -------------KSKDKRKGRKRSREESRSRSR-------SRSKSERSRKRGSKRDSKA 388
KS+ R+G RS E +++SR SRS E +RK R S++
Sbjct: 1651 GSSSTESSPEHPPKSRTARRG-SRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRS 1709
Query: 389 GSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNS 448
SS + + T RSP SVS KS SS+R S T T R RS S
Sbjct: 1710 ASSSPETRSRTPPRHRRSP--SVSSPEPAEKSRSSRRRRSASSPRTKT---TSRRGRSPS 1764
Query: 449 KSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
KP SRSRS+ +R + RS S S+S SR R RS SRS
Sbjct: 1765 -PKPRGLQRSRSRSRREKTRTTRRRDRSGS-SQSTSRRRQRSRSRS 1808
Score = 100 bits (250), Expect = 2e-21
Identities = 103/324 (31%), Positives = 143/324 (44%), Gaps = 17/324 (5%)
Query: 181 RRRSYSRSRSHSR-SRSRSRHSRKSRSRSGS---SKSSHSKS-RSRSRSGSRSRSKSRSR 235
RR SRSR+ +R RSRSR R+ RSRS S SHS++ + R RSGS S K++SR
Sbjct: 676 RRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSR 735
Query: 236 -SQSRSRSKKEKSRSPSKEKS-RSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
SQ RSRS S+ S RSRS S+ +S++KS+ + + K KS++P R
Sbjct: 736 TSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR 795
Query: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSL--RQSRSRSRSKGGSRSRSRSRSKSK 351
S+ +++ R R S S Q+ RQS S S +S + R S
Sbjct: 796 RSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSI 855
Query: 352 DKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV 411
+ ++S R S + R R S +GSS + K T Q SPSRS
Sbjct: 856 TSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQ--SPSRSS 913
Query: 412 SKE-REHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRS 470
S + + A QR G S + + +R+ R + P ESR + S
Sbjct: 914 SPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPR-----YS 968
Query: 471 RSKSRSRSASRSPSRSRSRSHSRS 494
S S S P +SHS S
Sbjct: 969 HSGSSSPDTKVKPETPPRQSHSGS 992
Score = 86.7 bits (213), Expect = 5e-17
Identities = 111/410 (27%), Positives = 163/410 (39%), Gaps = 89/410 (21%)
Query: 164 EVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRK-------------------- 203
++NG + +E P + +RS HS S K
Sbjct: 1354 DLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRT 1413
Query: 204 -SRSRSGSSKSSHSKS------RSRSRSGSR-------------------------SRSK 231
SR RS S+ S K RSRSGS R+
Sbjct: 1414 PSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTP 1473
Query: 232 SRSRSQSRS--------RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
SR RS+ S ++ + +SRSPS + ++ + + RS S+ ++K +
Sbjct: 1474 SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPL 1533
Query: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSR 343
G+ +SRS S + K + QER E S+ +++ ++SRS S + S+SR
Sbjct: 1534 GQ-RSRSGSSQELDVKPSASPQER--SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590
Query: 344 ---SRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTD 400
RSRS S + K + R+ ++S S S + + R R S++GSS K
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK------G 1644
Query: 401 RSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESR- 459
R S S S EH + R G S T T R RS S+S P L ++R
Sbjct: 1645 RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRS-SRSSPELTRKARL 1703
Query: 460 -SRSKSAS---KTRSRSKSRSRSA-----------SRSPSRSRSRSHSRS 494
RS+SAS +TRSR+ R R + SRS R RS S R+
Sbjct: 1704 SRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRT 1753
Score = 85.9 bits (211), Expect = 8e-17
Identities = 116/465 (24%), Positives = 181/465 (38%), Gaps = 115/465 (24%)
Query: 139 RKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRS 198
+KNE + SD +DG+ + ++ +P + YS R S SRS +
Sbjct: 130 KKNERLRAAFGISD-----SYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPT 184
Query: 199 RHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRS---------------K 243
+K + + + S S S R R S + K RS S+S+ R K
Sbjct: 185 PKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKK 244
Query: 244 KEKSRS-------------------PSKEKSRSRSHS----------AGKSRSKSKDQAE 274
+++SRS S + SRSRS S AG+S S + +
Sbjct: 245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304
Query: 275 EKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSR-GRSQEKSL------ 327
E G ++ PS ++ +K S E + +++K S +R S E+S
Sbjct: 305 EGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPP 364
Query: 328 RQSRSRSRSKGGS-------------------RSRSRSRSKSKDKRKGRKRSREES---- 364
+ + GGS S +R RS K K + S ES
Sbjct: 365 APTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPS 424
Query: 365 ---RSRSRSRSKSERSRK----RGSKRDSKAGSSKKKK---KEDTDRSQSRSPSRSVSKE 414
SR S S S K GS R+ + + K + + D+S S +PSR + +
Sbjct: 425 PQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRS 484
Query: 415 RE------------------HAKSESSQREGRGESENAGTNQETRSRSRSNSKSKP---- 452
R H++S S Q ++ G ++ + R RS S +P
Sbjct: 485 RSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSR 544
Query: 453 NLPSESRSRSKSASKTRSRSKS---RSRSASRSPSRSRSRSHSRS 494
+ ++ R RS+SA + RS S+S R RS SR+P+R R RS SR+
Sbjct: 545 SRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPAR-RGRSRSRT 588
Score = 81.3 bits (199), Expect = 2e-15
Identities = 132/494 (26%), Positives = 191/494 (38%), Gaps = 95/494 (19%)
Query: 80 GSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGR 139
G RS RRSGR + P R R + + R + +R+ + +GR
Sbjct: 667 GRSRSRTPARRSGRSRSRTPAR---RGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGR 723
Query: 140 KNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSR 199
S S+ K + + + + SRR RS S RS ++SR R
Sbjct: 724 SG-------SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLR 776
Query: 200 HSRKSRSRSGSSKSSHSKSRS---RSRSGSRSRSKSRSRS---QSRSRSK---KEKSRSP 250
RS SGSS KS++ RSRSGS S+ K++SR+ +SRS S K+KS++P
Sbjct: 777 -----RSLSGSSPCPKQKSQTPPRRSRSGS-SQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830
Query: 251 SKEKSRSRS-HSAGKSRSKSKDQAEEKIQNNDNVGKP--------------KSRSPSRHK 295
S++ S S H KS + + + Q N+ P KSR+PSRH
Sbjct: 831 SRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHS 890
Query: 296 SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSR--SRSKSKDK 353
S R + + S + + K++ R RS S S S SR SR+ +
Sbjct: 891 CSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRS 950
Query: 354 RKGRKRSREESR-----SRSRSRSKSERSRKRGSKRDSKAGSSKK--KKKEDTDRSQSRS 406
R S ESR S S S S + + R S +GS K K T S S
Sbjct: 951 RSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLS 1010
Query: 407 PSRSVSKEREHAKS----------------------------ESSQREGRGESENAGTNQ 438
S+S + + S S Q +G+ ++ +
Sbjct: 1011 GSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSD 1070
Query: 439 ETRSRSRSNSKSKPNLPSES-------RSRSKS-----ASKTRSRSKSRSRSAS------ 480
+ R + P+L S+S RSRS S AS++ R SAS
Sbjct: 1071 TSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSG 1130
Query: 481 RSPSRSRSRSHSRS 494
SP +SR +S S S
Sbjct: 1131 MSPEQSRFQSDSSS 1144
Score = 71.2 bits (173), Expect = 2e-12
Identities = 67/234 (28%), Positives = 100/234 (42%), Gaps = 11/234 (4%)
Query: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKS-SHSKSRSRSRSGSRSRSKSRSRSQ 237
++ RRS S S S S S S S S S S SGSS S S S + R S + +
Sbjct: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP 2586
Query: 238 SRS-RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS 296
+ R + +P+K K RS S S+ S S S + ++ + S S S S
Sbjct: 2587 KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
Query: 297 KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKG 356
S S ++ + + K S + E+ R R S SRS S S +
Sbjct: 2647 SSPSPAKPGPQAL--PKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVE------- 2697
Query: 357 RKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRS 410
R+R + R + S SER +RG + DS++ S K++++ + R SRS
Sbjct: 2698 RRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
Score = 68.6 bits (166), Expect = 1e-11
Identities = 84/334 (25%), Positives = 127/334 (38%), Gaps = 28/334 (8%)
Query: 181 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS 240
R R+ + S SR S S SR S+S ++ + RS S +SR
Sbjct: 2406 RSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQ 2465
Query: 241 RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS 300
+ S+S S + + SAG A + ++D VG+P + + ++ S +
Sbjct: 2466 TTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPG-VPHSD-VGEPPASTGAQQPSALAA 2523
Query: 301 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGS--------------RSRSRS 346
++ERR S S S S S S S S R S +
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
Query: 347 RSKSKDKRKGR-------KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDT 399
+ + R+GR KR R S S S S S S S S S + SS +
Sbjct: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Query: 400 DRSQSRSPSR----SVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLP 455
S S SP++ ++ K K +R R + + +++RS S S + + P
Sbjct: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703
Query: 456 SESRSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
S +S+S R S+ R SRSPS R R
Sbjct: 2704 QPSPRDQQSSSSERG-SRRGQRGDSRSPSHKRRR 2736
Score = 59.3 bits (142), Expect = 8e-09
Identities = 71/248 (28%), Positives = 91/248 (36%), Gaps = 30/248 (12%)
Query: 219 RSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQ 278
RS S S S S S S S S S S S S S S+ S R S A ++
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
Query: 279 NNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKG 338
G+P +P++ K +S S S S S S S S S S S S
Sbjct: 2591 RE---GRPPEPTPAKRKRRSSSSSSS-----------SSSSSSSSSSSSSSSSSSSSSSS 2636
Query: 339 GSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKED 398
S S S S S S K ++ + S + RSR DS S
Sbjct: 2637 SSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDS-------- 2688
Query: 399 TDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNS-KSKPNLPSE 457
RS S SP ER + S R+ + S G+ + R SRS S K + PS
Sbjct: 2689 --RSLSYSP-----VERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSP 2741
Query: 458 SRSRSKSA 465
R +S+
Sbjct: 2742 RPMRHRSS 2749
Score = 35.4 bits (80), Expect = 0.12
Identities = 55/238 (23%), Positives = 81/238 (34%), Gaps = 41/238 (17%)
Query: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
SR+P S + RS GS + SL +R G + + R
Sbjct: 2327 SRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVP 2386
Query: 348 SKSKDKRKGRK--------RSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDT 399
+ ++ GR RSR + S+SR SER+ S+ S +D
Sbjct: 2387 LSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD- 2445
Query: 400 DRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSN----SKSKPNLP 455
Q RSP S ++ + +S ++G T S + + S P +P
Sbjct: 2446 ---QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
Query: 456 -------------------------SESRSRSKSASKTRSRSKSRSRSASRSPSRSRS 488
E RS S S+S + S S S S S+S S S S S
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSS 2560
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 145 bits (367), Expect = 6e-35
Identities = 100/317 (31%), Positives = 160/317 (50%), Gaps = 24/317 (7%)
Query: 173 VEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKS 232
+E + G R RSRSH+RS+SRS S KS SR K S SK RSRS + SRSR K
Sbjct: 293 IEPESGKSNERKGGRSRSHTRSKSRS--SSKSHSRR---KRSQSKHRSRSHNRSRSRQKD 347
Query: 233 RSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSR-SKSKDQAEEKIQNNDNVGKPKSRSP 291
R RS+S K++S+S + KSRSRSHS K + ++ K + +E+++ D + K R
Sbjct: 348 RRRSKS---PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKD---REKERER 401
Query: 292 SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351
+ + K K R ++++R E EK +EK + R R R K + R + + K +
Sbjct: 402 EKEREKEKERGKNKDRDKEREK--------DREKDKEKDREREREKEHEKDRDKEKEKEQ 453
Query: 352 DKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV 411
DK K R++ R + R + K R+ R ++ SS ++++ RS SRSP S
Sbjct: 454 DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK 513
Query: 412 SKEREHAKSESSQREGRGESENAGTN---QETRSRSRSNSKSKPNLPSESRSRSKSASKT 468
+ +R+ ++S S + + + + E R R RS S K + + + + + S T
Sbjct: 514 TIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNS-T 572
Query: 469 RSRSKSRSRSASRSPSR 485
+ K ++ S S+
Sbjct: 573 SLKEKEHNKEPDSSVSK 589
Score = 125 bits (314), Expect = 9e-29
Identities = 88/298 (29%), Positives = 150/298 (50%), Gaps = 14/298 (4%)
Query: 176 KPGSRRRRSYSRSRSHSR--SRSRSRHSRKSRSRSGSSKSSHSKSRSR-SRSGSRSRSKS 232
K + RS S +RS SR R RS+ K RS+S + S S+S SR R +R + K
Sbjct: 327 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 386
Query: 233 RSRSQSRSRSK-KEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGK-PKSRS 290
+ R + + R K +E+ + KEK R ++ K R K +++ +EK + + + K R
Sbjct: 387 KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRD 446
Query: 291 PSRHKSKSKSRSRSQERRVE-EEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSK 349
+ K + K + R ++R E +EKR + R+ +S SR RSRS R R RSRS
Sbjct: 447 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR-RSRSSSRERRRRRSRSS 505
Query: 350 SKDKRKGRKRSREESRSRS-RSRSKSERSRKR-----GSKRDSKAGSSKKKKKEDTDRSQ 403
S+ R + R+ SRS S RSR+K ++ R++ +R+ + +S +K D D +
Sbjct: 506 SRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKE 565
Query: 404 SRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSK-SKPNLPSESRS 460
+ + KE+EH K S + ++A +E + + N + ++ NL +++ +
Sbjct: 566 KLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEA 623
Score = 121 bits (303), Expect = 2e-27
Identities = 78/253 (30%), Positives = 122/253 (48%), Gaps = 27/253 (10%)
Query: 245 EKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRS 304
E +S ++ RSRSH+ KSRS SK + K RS S+H+S+S +RSRS
Sbjct: 296 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRK------------RSQSKHRSRSHNRSRS 343
Query: 305 QERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR---KGRKRSR 361
+++ R + KS + RS+SR + SRSRS SR K KD R K ++R +
Sbjct: 344 RQK------------DRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 391
Query: 362 EESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSE 421
E+ R + R R K K K + +K +++D ++ + R + K+R+ K +
Sbjct: 392 EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEK 451
Query: 422 SSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASR 481
+E E + + E R + + + + + RSRS S + R RS+S SRS
Sbjct: 452 EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRT 511
Query: 482 SPSRSRSRSHSRS 494
S + R S S S
Sbjct: 512 SKTIKRKSSRSPS 524
Score = 90.9 bits (224), Expect = 2e-18
Identities = 67/254 (26%), Positives = 114/254 (44%), Gaps = 39/254 (15%)
Query: 279 NNDNVGKPKSRSP---SRHKSKSKSRSRSQERRVEE--EKRGSVSRGRSQEKSLRQSRSR 333
+N+ + KP +P ++ + R R + + E S R +S +RS+
Sbjct: 256 SNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSK 315
Query: 334 SR-------------SKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKR 380
SR SK SRS +RSRS+ KD+R+ + ++ S+SR R +S+S RS R
Sbjct: 316 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS-RSHSR 374
Query: 381 GSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQET 440
++D++ +K++ ++ DR + R + KE+E K++ +E + E
Sbjct: 375 DKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE 434
Query: 441 RSRSRSNSKSKPNLPSESRSRSKSASKTRSR--------------------SKSRSRSAS 480
R R + + K + + + + K K RS+ + RSRS+S
Sbjct: 435 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 494
Query: 481 RSPSRSRSRSHSRS 494
R R RSRS SRS
Sbjct: 495 RERRRRRSRSSSRS 508
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 145 bits (367), Expect = 6e-35
Identities = 100/317 (31%), Positives = 160/317 (50%), Gaps = 24/317 (7%)
Query: 173 VEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKS 232
+E + G R RSRSH+RS+SRS S KS SR K S SK RSRS + SRSR K
Sbjct: 177 IEPESGKSNERKGGRSRSHTRSKSRS--SSKSHSRR---KRSQSKHRSRSHNRSRSRQKD 231
Query: 233 RSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSR-SKSKDQAEEKIQNNDNVGKPKSRSP 291
R RS+S K++S+S + KSRSRSHS K + ++ K + +E+++ D + K R
Sbjct: 232 RRRSKS---PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKD---REKERER 285
Query: 292 SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351
+ + K K R ++++R E EK +EK + R R R K + R + + K +
Sbjct: 286 EKEREKEKERGKNKDRDKEREK--------DREKDKEKDREREREKEHEKDRDKEKEKEQ 337
Query: 352 DKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV 411
DK K R++ R + R + K R+ R ++ SS ++++ RS SRSP S
Sbjct: 338 DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK 397
Query: 412 SKEREHAKSESSQREGRGESENAGTN---QETRSRSRSNSKSKPNLPSESRSRSKSASKT 468
+ +R+ ++S S + + + + E R R RS S K + + + + + S T
Sbjct: 398 TIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNS-T 456
Query: 469 RSRSKSRSRSASRSPSR 485
+ K ++ S S+
Sbjct: 457 SLKEKEHNKEPDSSVSK 473
Score = 125 bits (314), Expect = 9e-29
Identities = 88/298 (29%), Positives = 150/298 (50%), Gaps = 14/298 (4%)
Query: 176 KPGSRRRRSYSRSRSHSR--SRSRSRHSRKSRSRSGSSKSSHSKSRSR-SRSGSRSRSKS 232
K + RS S +RS SR R RS+ K RS+S + S S+S SR R +R + K
Sbjct: 211 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 270
Query: 233 RSRSQSRSRSK-KEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGK-PKSRS 290
+ R + + R K +E+ + KEK R ++ K R K +++ +EK + + + K R
Sbjct: 271 KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRD 330
Query: 291 PSRHKSKSKSRSRSQERRVE-EEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSK 349
+ K + K + R ++R E +EKR + R+ +S SR RSRS R R RSRS
Sbjct: 331 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR-RSRSSSRERRRRRSRSS 389
Query: 350 SKDKRKGRKRSREESRSRS-RSRSKSERSRKR-----GSKRDSKAGSSKKKKKEDTDRSQ 403
S+ R + R+ SRS S RSR+K ++ R++ +R+ + +S +K D D +
Sbjct: 390 SRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKE 449
Query: 404 SRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSK-SKPNLPSESRS 460
+ + KE+EH K S + ++A +E + + N + ++ NL +++ +
Sbjct: 450 KLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEA 507
Score = 121 bits (303), Expect = 2e-27
Identities = 78/253 (30%), Positives = 122/253 (48%), Gaps = 27/253 (10%)
Query: 245 EKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRS 304
E +S ++ RSRSH+ KSRS SK + K RS S+H+S+S +RSRS
Sbjct: 180 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRK------------RSQSKHRSRSHNRSRS 227
Query: 305 QERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR---KGRKRSR 361
+++ R + KS + RS+SR + SRSRS SR K KD R K ++R +
Sbjct: 228 RQK------------DRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 275
Query: 362 EESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSE 421
E+ R + R R K K K + +K +++D ++ + R + K+R+ K +
Sbjct: 276 EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEK 335
Query: 422 SSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASR 481
+E E + + E R + + + + + RSRS S + R RS+S SRS
Sbjct: 336 EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRT 395
Query: 482 SPSRSRSRSHSRS 494
S + R S S S
Sbjct: 396 SKTIKRKSSRSPS 408
Score = 90.9 bits (224), Expect = 2e-18
Identities = 67/254 (26%), Positives = 114/254 (44%), Gaps = 39/254 (15%)
Query: 279 NNDNVGKPKSRSP---SRHKSKSKSRSRSQERRVEE--EKRGSVSRGRSQEKSLRQSRSR 333
+N+ + KP +P ++ + R R + + E S R +S +RS+
Sbjct: 140 SNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSK 199
Query: 334 SR-------------SKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKR 380
SR SK SRS +RSRS+ KD+R+ + ++ S+SR R +S+S RS R
Sbjct: 200 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS-RSHSR 258
Query: 381 GSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQET 440
++D++ +K++ ++ DR + R + KE+E K++ +E + E
Sbjct: 259 DKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE 318
Query: 441 RSRSRSNSKSKPNLPSESRSRSKSASKTRSR--------------------SKSRSRSAS 480
R R + + K + + + + K K RS+ + RSRS+S
Sbjct: 319 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 378
Query: 481 RSPSRSRSRSHSRS 494
R R RSRS SRS
Sbjct: 379 RERRRRRSRSSSRS 392
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 141 bits (355), Expect = 2e-33
Identities = 95/270 (35%), Positives = 144/270 (53%), Gaps = 21/270 (7%)
Query: 227 RSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP 286
R + RSRS RS S + RSP +SRSRSH S S D+ E+ + + +
Sbjct: 253 RHVERRRSRSPRRSLSPR---RSP--RRSRSRSHHREGHGSSSFDRELEREKERQRLER- 306
Query: 287 KSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346
++ + K + RSRS +R +E R RS+ + +SRSRSR + G R R R
Sbjct: 307 ----EAKEREKERRRSRSIDRGLE--------RRRSRSRERHRSRSRSRDRKGDR-RDRD 353
Query: 347 RSKSKDKRKGRKRSREESRSRSRSRSKS-ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSR 405
R + K+ +GR+R R+ + R R K ERSR+R ++ S+ +KK KED D + R
Sbjct: 354 REREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHR 413
Query: 406 SPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSR-SNSKSKPNLPSESRSRSKS 464
R KE++H++S S +R+ R S + + +RSRS+ +SK K +S RS+S
Sbjct: 414 DDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRS 473
Query: 465 ASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
S+ R+ S +S+ SPS+ +SR SRS
Sbjct: 474 GSQGRTDSVEKSKKREHSPSKEKSRKRSRS 503
Score = 140 bits (352), Expect = 3e-33
Identities = 105/322 (32%), Positives = 144/322 (44%), Gaps = 23/322 (7%)
Query: 159 KLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKS 218
K DG E R VE + RRS S RS RSRSRS H S S + K
Sbjct: 241 KKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKE 300
Query: 219 RSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQ 278
R R ++ R K R RS+S R E+ RS S+E+ RSRS S + + E + +
Sbjct: 301 RQRLEREAKEREKERRRSRSIDRGL-ERRRSRSRERHRSRSRSRDRKGDRRDRDREREKE 359
Query: 279 NNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKG 338
N + + R + K R RS+ER E+ RG V + +E K
Sbjct: 360 NERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKE-----------DKD 408
Query: 339 GSRSRSRSRSKSKDKRKGRKRSREES-RSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKE 397
R R R K+K+ R RSRE RSRSRSR+ +RSR R ++ SK + K+K
Sbjct: 409 DRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSN 468
Query: 398 DTDR--SQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLP 455
R SQ R+ S SK+REH+ S+ R+ E RS R +S SK
Sbjct: 469 KRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKE--------RSHKRDHSDSKDQSD 520
Query: 456 SESRSRSKSASKTRSRSKSRSR 477
R RS+S + + +++
Sbjct: 521 KHDRRRSQSIEQESQEKQHKNK 542
Score = 122 bits (306), Expect = 7e-28
Identities = 73/229 (31%), Positives = 119/229 (51%), Gaps = 9/229 (3%)
Query: 178 GSRRRRSYSRSRSHSRSRSRSRHS-RKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRS 236
G RRRS SR R SRSRSR R R+ R R ++ + R R R + + R
Sbjct: 324 GLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERE 383
Query: 237 QSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR-HK 295
+SR RSK+++SR +EK + R +D +EK + +SRS R H+
Sbjct: 384 RSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHS-------RSRSRERKHR 436
Query: 296 SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRK 355
S+S+SR+ + R +++ S + S+EKS ++SRS S+ + S +S+ R S K K
Sbjct: 437 SRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEK 496
Query: 356 GRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQS 404
RKRSR + RS R S S+ + +R S++ + ++K+ ++ ++
Sbjct: 497 SRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDET 545
Score = 95.5 bits (236), Expect = 1e-19
Identities = 59/195 (30%), Positives = 105/195 (53%), Gaps = 12/195 (6%)
Query: 174 EDKPGSRRRRSYSRSRSHSRSRSRSR---HSRKSRSRSGSSKSSHSKSRSRSRSGSRSRS 230
E++ G RR R Y + R + R + R R S++ RSR + H + + R R
Sbjct: 359 ENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRD 418
Query: 231 KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGK-SRSKSKDQAEEKIQNNDNVGKPKSR 289
+ + SRSRS++ K RS RSRS +AGK SRS+SK+++ + + +SR
Sbjct: 419 SKKEKKHSRSRSRERKHRS------RSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSR 472
Query: 290 SPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSK 349
S S+ ++ S +S+ +E +EK S R RS+E+S ++ S S+ + R RS+S
Sbjct: 473 SGSQGRTDSVEKSKKREHSPSKEK--SRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSI 530
Query: 350 SKDKRKGRKRSREES 364
++ ++ + ++++E+
Sbjct: 531 EQESQEKQHKNKDET 545
Score = 86.3 bits (212), Expect = 6e-17
Identities = 80/255 (31%), Positives = 125/255 (49%), Gaps = 27/255 (10%)
Query: 63 ERVIVEHARGPRRDGSYGSG--------RSGYGYRRSGRDKYGPPTRTEYRLIVENLSSR 114
ER E + RR S G R + R RD+ G + EN R
Sbjct: 305 EREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGR 364
Query: 115 CSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVE 174
+ +DY ++ G + + R+ E S +++ K D + R +
Sbjct: 365 ---RRDRDYDKERGNEREKERERSRERSK--EQRSRGEVEEKKHKEDKDDRRHR-----D 414
Query: 175 DKPGSRRRRSYSRSRSHSR---SRSRSRHS-RKSRSRSGSSKSSHSKSRSRSRSGSRSRS 230
DK S++ + +SRSRS R SRSRSR++ ++SRSRS KSS K+ S+ +S RSRS
Sbjct: 415 DKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRS-KEKSSKHKNESKEKSNKRSRS 473
Query: 231 KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS 290
S+ R+ S +SKK + SPSKEKSR RS S K RS +D ++ K Q +D + +S+S
Sbjct: 474 GSQGRTDSVEKSKK-REHSPSKEKSRKRSRS--KERSHKRDHSDSKDQ-SDKHDRRRSQS 529
Query: 291 PSRHKSKSKSRSRSQ 305
+ + + +++ +
Sbjct: 530 IEQESQEKQHKNKDE 544
Score = 70.1 bits (170), Expect = 4e-12
Identities = 66/226 (29%), Positives = 95/226 (42%), Gaps = 36/226 (15%)
Query: 282 NVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSR 341
N+ + P + K K + +R VE + S R S +S R+SRSRS + G
Sbjct: 228 NIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHG 287
Query: 342 SRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDR 401
S S R ++K R+R E++ R + R +S RS RG +R R
Sbjct: 288 SSSFDRELEREKE--RQRLEREAKEREKERRRS-RSIDRGLERR---------------R 329
Query: 402 SQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSR 461
S+SR RS S+ R+ K + R+ E E N+ R R R K + N + R R
Sbjct: 330 SRSRERHRSRSRSRDR-KGDRRDRDREREKE----NERGRRRDRDYDKERGNEREKERER 384
Query: 462 SKSASK-TRSRSK------------SRSRSASRSPSRSRSRSHSRS 494
S+ SK RSR + R R R + + S SRS
Sbjct: 385 SRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRS 430
>gi|118582269 splicing factor, arginine/serine-rich 1 isoform 2
[Homo sapiens]
Length = 201
Score = 136 bits (343), Expect = 4e-32
Identities = 79/174 (45%), Positives = 104/174 (59%), Gaps = 11/174 (6%)
Query: 3 RVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYG-----FVEFDDLRDADDAVYELNG 57
R+Y+G L R +D+E F YG I ++DLKN G FVEF+D RDA+DAVY +G
Sbjct: 17 RIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDG 76
Query: 58 KDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTR-TEYRLIVENLSSRCS 116
D G R+ VE R R G G G G G + R +YGPP+R +E R++V L S
Sbjct: 77 YDYDGYRLRVEFPRSGRGTGRGGGGGGGGG---APRGRYGPPSRRSENRVVVSGLPPSGS 133
Query: 117 WQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKI 170
WQDLKD+MR+AG+V YAD + R GV+EFV DM A+ KLD T+ ++
Sbjct: 134 WQDLKDHMREAGDVCYADVY--RDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEV 185
>gi|4506903 splicing factor, arginine/serine-rich 9 [Homo sapiens]
Length = 221
Score = 136 bits (342), Expect = 5e-32
Identities = 89/210 (42%), Positives = 120/210 (57%), Gaps = 21/210 (10%)
Query: 3 RVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYG-----FVEFDDLRDADDAVYELNG 57
R+Y+G L RE+D+E F YG+I E++LKN +G FV F+D RDA+DA+Y NG
Sbjct: 15 RIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNG 74
Query: 58 KDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTR-TEYRLIVENLSSRCS 116
D R+ VE R +YG GR G+ R GR+ GPPTR +++R++V L S
Sbjct: 75 YDYGQCRLRVEFPR------TYG-GRGGWP--RGGRN--GPPTRRSDFRVLVSGLPPSGS 123
Query: 117 WQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGR--KIRLVE 174
WQDLKD+MR+AG+V YAD K G++E++ DM+ AL KLD T+ + +
Sbjct: 124 WQDLKDHMREAGDVCYADVQK--DGVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYIR 181
Query: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKS 204
P YSRSRS SR R SR S
Sbjct: 182 VYPERSTSYGYSRSRSGSRGRDSPYQSRGS 211
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 135 bits (339), Expect = 1e-31
Identities = 111/357 (31%), Positives = 180/357 (50%), Gaps = 50/357 (14%)
Query: 161 DGTEVNGRK------IRLVEDKPGSRRRRSYSRSRSHSRSR-SRSRHSRKSRSRSGSSKS 213
DG VN +K ++E K + + RSRS S S S S +SR S + S S S
Sbjct: 475 DGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSS 534
Query: 214 SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHS------AGKSRS 267
S+S S SR+ SRS S R + SRSRS K+R +SRSRS+S + ++R
Sbjct: 535 SYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKAR-----RSRSRSYSRRIKIESNRARV 589
Query: 268 KSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSR-----------SQERRVEEEKRGS 316
K +D+ +N+ + ++RSPSR + +S+SRSR S++RR +++RG+
Sbjct: 590 KIRDRRRSN-RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGN 648
Query: 317 VSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSER 376
+S + K +K R + RSRS KD++K K E R + + E+
Sbjct: 649 LSGNSHKHKG--------EAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEK 700
Query: 377 SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGT 436
K S+ D + K+K +++R+ SRS S SV R ++ +S + + +++G+
Sbjct: 701 DFKFSSQDD------RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGS 754
Query: 437 NQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
+ RS S S SK E +++ S++RS KS+ RS ++ + +S+S SR
Sbjct: 755 DSSGRSSSESPGSSK-----EKKAKKPKHSRSRSVEKSQ-RSGKKASRKHKSKSRSR 805
Score = 105 bits (261), Expect = 1e-22
Identities = 101/331 (30%), Positives = 150/331 (45%), Gaps = 60/331 (18%)
Query: 212 KSSHSKSRSRSRSGSRSRSKSRSRSQSRS--RSKKEKSRSPSKEKSRSRSHSAGKSRSKS 269
++S S +R G K R+ +++ S KKE + +SRS S S+G S S S
Sbjct: 463 QNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNS 522
Query: 270 KDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQ 329
+ + ++ S S S S++ SRS S +R+ SR RS R+
Sbjct: 523 RTSSTSSTVSSS------SYSSSSGSSRTSSRSSSPKRKKRH------SRSRSPTIKARR 570
Query: 330 SRSRS------------RSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSR-------- 369
SRSRS R K R RS S +++R+ R SRE RSRSR
Sbjct: 571 SRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNR 630
Query: 370 -SRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV-------SKEREHAKSE 421
SRS+S RK +R + +G+S K K E ++ + + SRS+ KERE + +
Sbjct: 631 ASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDK 690
Query: 422 SSQREGRGESENAGTNQETRSR---------SRSNSKSKPNLPSESRSRSKSA----SKT 468
+++ R E + ++Q+ R + SRS S S + +SR SK + SK
Sbjct: 691 RKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKK 750
Query: 469 RSRSKSRSRSASRSPSRSRSR-----SHSRS 494
S S S RS+S SP S+ + HSRS
Sbjct: 751 HSGSDSSGRSSSESPGSSKEKKAKKPKHSRS 781
Score = 90.1 bits (222), Expect = 4e-18
Identities = 78/288 (27%), Positives = 122/288 (42%), Gaps = 19/288 (6%)
Query: 208 SGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRS 267
SG S+ S S S + R R + + +KEK + +K + +
Sbjct: 393 SGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVT 452
Query: 268 KSKDQAEEKIQNN----------DNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSV 317
K ++ K QN+ +V K R+P+ S + + +E+ + R
Sbjct: 453 KEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGS 512
Query: 318 SRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERS 377
S S + R S + S S S S S++ + KR + SRSRS + K+ RS
Sbjct: 513 SSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPT-IKARRS 571
Query: 378 RKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSES-SQREGRGESENAGT 436
R R R K S++ + K R + RS S+ +ER +S S +R R S + T
Sbjct: 572 RSRSYSRRIKIESNRARVK---IRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRT 628
Query: 437 NQETRSRSRSNSK---SKPNLPSESRSRSKSASKTRSRSKSRSRSASR 481
N+ +RSRSR K + NL S + K +K + R K RSRS +
Sbjct: 629 NRASRSRSRDRRKIDDQRGNLSGNSH-KHKGEAKEQERKKERSRSIDK 675
Score = 68.6 bits (166), Expect = 1e-11
Identities = 71/342 (20%), Positives = 129/342 (37%), Gaps = 71/342 (20%)
Query: 223 RSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAG---KSRSKSKDQAEEKIQN 279
R G + + + + R ++++S+ KEK + G + +SK ++E+ ++
Sbjct: 237 REGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEED 296
Query: 280 NDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSV---------------------- 317
+NV S +R S S EEEK +
Sbjct: 297 TENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYY 356
Query: 318 -------SRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGR---KRSREESRSR 367
++ K L QS + + G S+D+R R ++ R
Sbjct: 357 VAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELR 416
Query: 368 SRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDR-------------------------- 401
R R K E ++ ++ +++K+ T+R
Sbjct: 417 HRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADG 476
Query: 402 ----SQSRSPSRSVS---KEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNL 454
+ R+P+ + S ++EH + E R G S + ++ +R+ S S++ S +
Sbjct: 477 DVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSY 536
Query: 455 PS---ESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
S SR+ S+S+S R + SRSRS + RSRSRS+SR
Sbjct: 537 SSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR 578
Score = 62.8 bits (151), Expect = 7e-10
Identities = 61/268 (22%), Positives = 113/268 (42%), Gaps = 28/268 (10%)
Query: 244 KEKSRSPSKEKSRSRS------------HSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
++ +++P+K+ ++S + + +G S + D+ E +D + + R
Sbjct: 363 RKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQK 422
Query: 292 SR-HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS 350
K K + ++++EEEK+ + E+ ++ + S S +R
Sbjct: 423 QEAFWRKEKEQQLLHDKQMEEEKQQT-------ERVTKEMNEFIHKEQNSLSLLEAREAD 475
Query: 351 KDKRKGRKRSREESRS----RSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRS 406
D +KR+ E+ S + + K ++ R R S + SS + + S S
Sbjct: 476 GDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSS 535
Query: 407 PSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSAS 466
S S R ++S S +R+ R + T + RSRSRS S+ + ES +R++
Sbjct: 536 YSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR---RIKIES-NRARVKI 591
Query: 467 KTRSRSKSRSRSASRSPSRSRSRSHSRS 494
+ R RS S R +RS SR RS
Sbjct: 592 RDRRRSNRNSIERERRRNRSPSRERRRS 619
Score = 38.9 bits (89), Expect = 0.011
Identities = 31/113 (27%), Positives = 46/113 (40%), Gaps = 2/113 (1%)
Query: 137 KGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRS 196
K ++ E +F S D + + + T I + + SR+ S ++ +
Sbjct: 694 KQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSG 753
Query: 197 RSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRS 249
R S GSSK +K SR SRS KS+ + SR K KSRS
Sbjct: 754 SDSSGRSSSESPGSSKEKKAKKPKHSR--SRSVEKSQRSGKKASRKHKSKSRS 804
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 135 bits (339), Expect = 1e-31
Identities = 111/357 (31%), Positives = 180/357 (50%), Gaps = 50/357 (14%)
Query: 161 DGTEVNGRK------IRLVEDKPGSRRRRSYSRSRSHSRSR-SRSRHSRKSRSRSGSSKS 213
DG VN +K ++E K + + RSRS S S S S +SR S + S S S
Sbjct: 475 DGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSS 534
Query: 214 SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHS------AGKSRS 267
S+S S SR+ SRS S R + SRSRS K+R +SRSRS+S + ++R
Sbjct: 535 SYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKAR-----RSRSRSYSRRIKIESNRARV 589
Query: 268 KSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSR-----------SQERRVEEEKRGS 316
K +D+ +N+ + ++RSPSR + +S+SRSR S++RR +++RG+
Sbjct: 590 KIRDRRRSN-RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGN 648
Query: 317 VSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSER 376
+S + K +K R + RSRS KD++K K E R + + E+
Sbjct: 649 LSGNSHKHKG--------EAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEK 700
Query: 377 SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGT 436
K S+ D + K+K +++R+ SRS S SV R ++ +S + + +++G+
Sbjct: 701 DFKFSSQDD------RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGS 754
Query: 437 NQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
+ RS S S SK E +++ S++RS KS+ RS ++ + +S+S SR
Sbjct: 755 DSSGRSSSESPGSSK-----EKKAKKPKHSRSRSVEKSQ-RSGKKASRKHKSKSRSR 805
Score = 105 bits (261), Expect = 1e-22
Identities = 101/331 (30%), Positives = 150/331 (45%), Gaps = 60/331 (18%)
Query: 212 KSSHSKSRSRSRSGSRSRSKSRSRSQSRS--RSKKEKSRSPSKEKSRSRSHSAGKSRSKS 269
++S S +R G K R+ +++ S KKE + +SRS S S+G S S S
Sbjct: 463 QNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNS 522
Query: 270 KDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQ 329
+ + ++ S S S S++ SRS S +R+ SR RS R+
Sbjct: 523 RTSSTSSTVSSS------SYSSSSGSSRTSSRSSSPKRKKRH------SRSRSPTIKARR 570
Query: 330 SRSRS------------RSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSR-------- 369
SRSRS R K R RS S +++R+ R SRE RSRSR
Sbjct: 571 SRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNR 630
Query: 370 -SRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV-------SKEREHAKSE 421
SRS+S RK +R + +G+S K K E ++ + + SRS+ KERE + +
Sbjct: 631 ASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDK 690
Query: 422 SSQREGRGESENAGTNQETRSR---------SRSNSKSKPNLPSESRSRSKSA----SKT 468
+++ R E + ++Q+ R + SRS S S + +SR SK + SK
Sbjct: 691 RKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKK 750
Query: 469 RSRSKSRSRSASRSPSRSRSR-----SHSRS 494
S S S RS+S SP S+ + HSRS
Sbjct: 751 HSGSDSSGRSSSESPGSSKEKKAKKPKHSRS 781
Score = 90.1 bits (222), Expect = 4e-18
Identities = 78/288 (27%), Positives = 122/288 (42%), Gaps = 19/288 (6%)
Query: 208 SGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRS 267
SG S+ S S S + R R + + +KEK + +K + +
Sbjct: 393 SGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVT 452
Query: 268 KSKDQAEEKIQNN----------DNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSV 317
K ++ K QN+ +V K R+P+ S + + +E+ + R
Sbjct: 453 KEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGS 512
Query: 318 SRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERS 377
S S + R S + S S S S S++ + KR + SRSRS + K+ RS
Sbjct: 513 SSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPT-IKARRS 571
Query: 378 RKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSES-SQREGRGESENAGT 436
R R R K S++ + K R + RS S+ +ER +S S +R R S + T
Sbjct: 572 RSRSYSRRIKIESNRARVK---IRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRT 628
Query: 437 NQETRSRSRSNSK---SKPNLPSESRSRSKSASKTRSRSKSRSRSASR 481
N+ +RSRSR K + NL S + K +K + R K RSRS +
Sbjct: 629 NRASRSRSRDRRKIDDQRGNLSGNSH-KHKGEAKEQERKKERSRSIDK 675
Score = 68.6 bits (166), Expect = 1e-11
Identities = 71/342 (20%), Positives = 129/342 (37%), Gaps = 71/342 (20%)
Query: 223 RSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAG---KSRSKSKDQAEEKIQN 279
R G + + + + R ++++S+ KEK + G + +SK ++E+ ++
Sbjct: 237 REGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEED 296
Query: 280 NDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSV---------------------- 317
+NV S +R S S EEEK +
Sbjct: 297 TENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYY 356
Query: 318 -------SRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGR---KRSREESRSR 367
++ K L QS + + G S+D+R R ++ R
Sbjct: 357 VAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELR 416
Query: 368 SRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDR-------------------------- 401
R R K E ++ ++ +++K+ T+R
Sbjct: 417 HRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADG 476
Query: 402 ----SQSRSPSRSVS---KEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNL 454
+ R+P+ + S ++EH + E R G S + ++ +R+ S S++ S +
Sbjct: 477 DVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSY 536
Query: 455 PS---ESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
S SR+ S+S+S R + SRSRS + RSRSRS+SR
Sbjct: 537 SSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR 578
Score = 62.8 bits (151), Expect = 7e-10
Identities = 61/268 (22%), Positives = 113/268 (42%), Gaps = 28/268 (10%)
Query: 244 KEKSRSPSKEKSRSRS------------HSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
++ +++P+K+ ++S + + +G S + D+ E +D + + R
Sbjct: 363 RKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQK 422
Query: 292 SR-HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS 350
K K + ++++EEEK+ + E+ ++ + S S +R
Sbjct: 423 QEAFWRKEKEQQLLHDKQMEEEKQQT-------ERVTKEMNEFIHKEQNSLSLLEAREAD 475
Query: 351 KDKRKGRKRSREESRS----RSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRS 406
D +KR+ E+ S + + K ++ R R S + SS + + S S
Sbjct: 476 GDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSS 535
Query: 407 PSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSAS 466
S S R ++S S +R+ R + T + RSRSRS S+ + ES +R++
Sbjct: 536 YSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR---RIKIES-NRARVKI 591
Query: 467 KTRSRSKSRSRSASRSPSRSRSRSHSRS 494
+ R RS S R +RS SR RS
Sbjct: 592 RDRRRSNRNSIERERRRNRSPSRERRRS 619
Score = 38.9 bits (89), Expect = 0.011
Identities = 31/113 (27%), Positives = 46/113 (40%), Gaps = 2/113 (1%)
Query: 137 KGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRS 196
K ++ E +F S D + + + T I + + SR+ S ++ +
Sbjct: 694 KQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSG 753
Query: 197 RSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRS 249
R S GSSK +K SR SRS KS+ + SR K KSRS
Sbjct: 754 SDSSGRSSSESPGSSKEKKAKKPKHSR--SRSVEKSQRSGKKASRKHKSKSRS 804
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 129 bits (325), Expect = 5e-30
Identities = 102/353 (28%), Positives = 165/353 (46%), Gaps = 42/353 (11%)
Query: 159 KLDGTEVNGRK------IRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSK 212
K D +E+N K +R+ E K R S S +R + + + H S+ R +
Sbjct: 382 KGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERD-IRR 440
Query: 213 SSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQ 272
+S + +++ R++SKSRS+S+ +S+SK+ S+ E+ R RS S G+ K
Sbjct: 441 NSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVK-- 498
Query: 273 AEEKIQNNDNVGKPKSRSPSRHKSKS---------KSRSRSQERRVEEEKRG-SVSRGRS 322
EK + +D+ GK + RS S+ KSK S+S+ ++RR + R +++G+
Sbjct: 499 --EKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKH 556
Query: 323 QEKSLRQSRSRSRSKGG---SRSRSRSRSKSKD---------KRKGRKRSREESRSRSRS 370
S + RSRSR + SR+ R RS+SK+ +R+GR RSRE RS
Sbjct: 557 SYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRS 616
Query: 371 RSKSERSRKRGSKRDSKAGSSKKKK--------KEDTDRSQSRSPSRSVSKEREHAKSES 422
RSK R R+R S+ + S + K K + S S R SK R+H S +
Sbjct: 617 RSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNN 676
Query: 423 SQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSR 475
S RE + + + + ++ +S + KS E S K +SK +
Sbjct: 677 S-REKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQ 728
Score = 121 bits (303), Expect = 2e-27
Identities = 106/358 (29%), Positives = 164/358 (45%), Gaps = 38/358 (10%)
Query: 151 SDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSR--HSRKSRSRS 208
S +R L G ++ GR G RR R+ SRSRS R R H R+ R+
Sbjct: 319 SYQRRLLVTRSGRKIKGR---------GPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRA 369
Query: 209 GSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKK-----EKSRSPSKEKSRSRSHSAG 263
+ S + + + K RS R + +K S SP+++ + +
Sbjct: 370 QRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDH 429
Query: 264 KSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS--RSRSQER-----RVEEEKRGS 316
KS SK +D +++ K K R+ S KS+SKS +S+S+ER R EE++ S
Sbjct: 430 KSNSKERDIRRNSEKDDKYKNKVKKRAKS--KSRSKSKEKSKSKERDSKHNRNEEKRMRS 487
Query: 317 VSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSER 376
S+GR E ++++ +S SKG + RSRS+ KSK + S+ S+S+ K R
Sbjct: 488 RSKGRDHE-NVKEKEKQSDSKGKDQERSRSKEKSK-----QLESKSNEHDHSKSKEKDRR 541
Query: 377 SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGT 436
++ R + D G + +RS+SR SR V + R H + S +E E
Sbjct: 542 AQSRSRECDITKGKHSYNSR-TRERSRSRDRSRRV-RSRTHDRDRSRSKEYHRYRE---- 595
Query: 437 NQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
QE R R RS S+ + P SRS+ + + SRS R S SR+ + R++ S
Sbjct: 596 -QEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSS 652
Score = 120 bits (300), Expect = 4e-27
Identities = 97/332 (29%), Positives = 159/332 (47%), Gaps = 41/332 (12%)
Query: 195 RSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR--SRSKSRSRSQSRSRSKKEKSRSPSK 252
++R R + + S +S+ + +RSG + R R R+ SRSRS+ RS +
Sbjct: 300 KNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETP 359
Query: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS----KSRSRSQERR 308
R A + R S ++ + ++ N K RSP R K + ++ S S R+
Sbjct: 360 PHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRK 419
Query: 309 VEEEKRGSVSRGRSQEKSLRQSRSRS---RSKGGSRSRSRSRSKSKDKRKGRKRS----- 360
E+EK+ + S+E+ +R++ + ++K R++S+SRSKSK+K K ++R
Sbjct: 420 NEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNR 479
Query: 361 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV-SKEREHAK 419
EE R RSRS+ + + K K+ G +D +RS+S+ S+ + SK EH
Sbjct: 480 NEEKRMRSRSKGRDHENVKEKEKQSDSKG-------KDQERSRSKEKSKQLESKSNEHDH 532
Query: 420 SESSQREGRGESENA---------GTNQETRSRSRSNSKSKPNLPSESRSRSKSASKT-- 468
S+S +++ R +S + N TR RSRS +S+ + S + R +S SK
Sbjct: 533 SKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSR-RVRSRTHDRDRSRSKEYH 591
Query: 469 -------RSRSKSRSRSASRSPSRSRSRSHSR 493
R R +SRSR P RSRS+ R
Sbjct: 592 RYREQEYRRRGRSRSRERRTPPGRSRSKDRRR 623
Score = 117 bits (294), Expect = 2e-26
Identities = 107/427 (25%), Positives = 182/427 (42%), Gaps = 28/427 (6%)
Query: 71 RGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVE-NLSSRCSW-----QDLKDYM 124
RGPRR + RS +RRS + P R E + +SS W +L +
Sbjct: 336 RGPRRYRTPSRSRSRDRFRRS---ETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIK 392
Query: 125 RQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRS 184
K + V E + + K K + R IR +K + +
Sbjct: 393 ENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKV 452
Query: 185 YSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKK 244
R++S SRS+S+ + K R S + + + R RSRS R + + + K
Sbjct: 453 KKRAKSKSRSKSKEKSKSKERD---SKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGK 509
Query: 245 EKSRSPSKEKSR---SRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSR 301
++ RS SKEKS+ S+S+ S+SK KD+ + ++ K K SR + +S+SR
Sbjct: 510 DQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSR 569
Query: 302 SRSQERRVEEEKRGSVSRGRSQE-------KSLRQSRSRSRSKGGSRSRSRSRSKSKDKR 354
RS+ R R R RS+E + R+ RSRSR + RSRS+ + + +R
Sbjct: 570 DRSRRVRSRTHDR---DRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRR 626
Query: 355 KGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKE 414
R REES+SR++ + +++ S+ K +S++ K D + S + ++ +
Sbjct: 627 DSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQ 686
Query: 415 REHAKSESSQREGRGESENAGTNQETRSRS---RSNSKSKPNLPSESRSRSKSASKTRSR 471
+K + S ++ +S ++ + RS + N KSK ++K S
Sbjct: 687 SPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSP 746
Query: 472 SKSRSRS 478
+S
Sbjct: 747 GTDEDKS 753
Score = 100 bits (248), Expect = 4e-21
Identities = 89/325 (27%), Positives = 151/325 (46%), Gaps = 32/325 (9%)
Query: 189 RSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSR 248
+S + + RH S S S SS S S S S S S + +S+ R + ++ SR
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239
Query: 249 SPSKEKS-RSRSHSAGKSRSKSKD---QAEEKIQNNDNVGKPKSRSPSRH---KSKSKSR 301
KEK R +S + S S++++ Q + ++ + P++R R K+ K R
Sbjct: 240 KHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKER 299
Query: 302 SRSQERRVEEEKRGSVSRGRSQEKSLRQSRS--RSRSKGGSRSRSRSRSKSKDK------ 353
+++ER E E S+ S ++ L +RS + + +G R R+ SRS+S+D+
Sbjct: 300 -KNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSET 358
Query: 354 ----RKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSR 409
R+ +R++ S K ++S K + ++ K++K R+ S SP+R
Sbjct: 359 PPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNR 418
Query: 410 SVSKERE--HAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASK 467
KE++ KS S +R+ R SE + +K K S+SRS+SK SK
Sbjct: 419 KNEKEKKVKDHKSNSKERDIRRNSEKD---------DKYKNKVKKRAKSKSRSKSKEKSK 469
Query: 468 TRSRSKSRSRSAS-RSPSRSRSRSH 491
++ R +R+ R SRS+ R H
Sbjct: 470 SKERDSKHNRNEEKRMRSRSKGRDH 494
Score = 65.5 bits (158), Expect = 1e-10
Identities = 77/338 (22%), Positives = 132/338 (39%), Gaps = 87/338 (25%)
Query: 243 KKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRS 302
+ +K+ + SK + R S G+ KSK + EEK ++ + S S S S S+S S
Sbjct: 155 ENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSS 214
Query: 303 RSQERR---VEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS--------------- 344
S + E+ K+ ++ K ++ + R +SK + S S
Sbjct: 215 DSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRP 274
Query: 345 --------------RSRSKSKDK-RKGRKRSREE-------------------------- 363
+S K+ +K RK R+R RE
Sbjct: 275 EEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIK 334
Query: 364 ----------SRSRSRSR--------------SKSERSRKRGSKRDSKAGSSKKKKKEDT 399
SRSRSR R +++R R +R K S+ + ++
Sbjct: 335 GRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKEN 394
Query: 400 DRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTN---QETRSRSRSNSKSKPNLPS 456
RS R R ++ R ++S + + E + ++ +N ++ R S + K K +
Sbjct: 395 QRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKK 454
Query: 457 ESRSRSKSASKTRSRSKSRSRSASRS-PSRSRSRSHSR 493
++S+S+S SK +S+SK R +R+ R RSRS R
Sbjct: 455 RAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGR 492
Score = 57.4 bits (137), Expect = 3e-08
Identities = 43/144 (29%), Positives = 67/144 (46%), Gaps = 7/144 (4%)
Query: 177 PGSRRRRSYSRSRSHSRS--RSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
PG R + R R SRS R S+ K + R+ SKSSH K S S S+S+ +
Sbjct: 613 PGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHN 672
Query: 235 RSQSRSRSKKEKSRSP-SKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
S + K ++ +SP SK K S+ + S K+K+ +EKI+++ KS+
Sbjct: 673 SSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKE--DEKIRSSVEKENQKSKGQEN 730
Query: 294 HKSKSKSRSRSQERR--VEEEKRG 315
K++ E +E+K G
Sbjct: 731 DHVHEKNKKFDHESSPGTDEDKSG 754
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 129 bits (323), Expect = 8e-30
Identities = 82/328 (25%), Positives = 142/328 (43%), Gaps = 37/328 (11%)
Query: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRS----GSSKSSHS-KSRSRSRSGSRS 228
E + R+R R+R R R ++R R+ R R ++ HS + R R R
Sbjct: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETE 219
Query: 229 RSKSRSRSQSRSRSKKEKS-RSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
R R R R ++ K+ R K+ R R+ R K +++ ++ ++ D K +
Sbjct: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER 279
Query: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
R R + + R R ER+ E ++ R R +E++ ++ R R R + R R R
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRE----RERERERNRKRERERERERERERQRETER 335
Query: 348 SKSKDKRKGRKRSREESRSRSRS-----RSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
+ K++ + RKR E R R+R R ++ER R+R +RD ++ +++++ D DR
Sbjct: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
Query: 403 QSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRS 462
+ + R K+R+ + QRE R + R + + R R
Sbjct: 396 RQKERERQTEKDRDGQRETEKQRE--------------REKDRESERG--------RERG 433
Query: 463 KSASKTRSRSKSRSRSASRSPSRSRSRS 490
+ K + R + R R R R R RS
Sbjct: 434 REREKQKGRERDRERQTDRQAGRQRKRS 461
Score = 128 bits (321), Expect = 1e-29
Identities = 77/310 (24%), Positives = 125/310 (40%), Gaps = 6/310 (1%)
Query: 183 RSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRS 242
R R R R R R RH + R R + + R R R R+R K R R R
Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETER-EG 135
Query: 243 KKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRS 302
++ + R ++ R R A K R + D+ E + Q N K + R +R + + + R
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTDR-ERQRQTERNRQKEREREKNRQERRERERQ 194
Query: 303 RSQERRVEE---EKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKR 359
R +E + E+ E+ R R E + R R + R R R K ++ + +R
Sbjct: 195 REKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASER 254
Query: 360 SREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK 419
E + R R R + +R R R K + K++++ + DR R R +ERE +
Sbjct: 255 ETERDKERERERDR-DRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERER 313
Query: 420 SESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSA 479
+ +RE E E + R R + + + R R++ + R R R
Sbjct: 314 NRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERER 373
Query: 480 SRSPSRSRSR 489
R R +R
Sbjct: 374 ERERDRQSAR 383
Score = 127 bits (319), Expect = 2e-29
Identities = 85/350 (24%), Positives = 151/350 (43%), Gaps = 22/350 (6%)
Query: 152 DMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSS 211
+ +R EK RK +K R+R + R R R + R R + + R R
Sbjct: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRH-RERQRDREKERERQTDRERDRQREK 119
Query: 212 KSSHSKSRSRS--RSGSRSRSKSRSRSQSRSRSK---KEKSRSPSKEKSRSRSHSAGKSR 266
+ + K R R R G R R + + R R + KE+ R +E+ R + K R
Sbjct: 120 ERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKER 179
Query: 267 SKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKS 326
+ K++ E + + + ++++ RH + + R R +E E E++ R R +++
Sbjct: 180 EREKNRQERRERERQR--EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRK 237
Query: 327 LRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSK--SERSRKRGSKR 384
R R K R R+ R +DK + R+R R+ R R + + ++R R+R ++R
Sbjct: 238 TE----REREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
Query: 385 DSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRS 444
D + +++K++ +R + R +R +ERE + QRE + E + R R
Sbjct: 294 DRE---TERKRERQRERERERERNRKRERERERERERERQRETERDRE----KERERKRK 346
Query: 445 RSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRS-PSRSRSRSHSR 493
R + R + A + R R + R R ++R R R R R
Sbjct: 347 RQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDR 396
Score = 127 bits (318), Expect = 3e-29
Identities = 84/363 (23%), Positives = 147/363 (40%), Gaps = 23/363 (6%)
Query: 150 YSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSG 209
+ + +R EK + + + R E + ++ R R R R R ++ R R
Sbjct: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153
Query: 210 SSKSSHSKS--RSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRS 267
++ + R R R R+R K R R ++R ++ + + + K+ R G+ R
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213
Query: 268 KSKD-QAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKS 326
+ ++ + E + + + + + R R + K R R+ ER E +K R R +++
Sbjct: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273
Query: 327 LRQS-----------RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKS- 374
RQ R R + R R R R + +++ + RKR RE R R R R +
Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333
Query: 375 ----ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE 430
E+ R+R KR ++ +++ T R R R +ERE + + +RE R E
Sbjct: 334 ERDREKERERKRKRQTE---MDRERNRQTGREGRRQAERERERERERDRQSAREREER-E 389
Query: 431 SENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRS 490
+ Q+ R R + + R R K R R + R R + R R R
Sbjct: 390 RDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQ 449
Query: 491 HSR 493
R
Sbjct: 450 TDR 452
Score = 120 bits (300), Expect = 4e-27
Identities = 82/340 (24%), Positives = 135/340 (39%), Gaps = 29/340 (8%)
Query: 174 EDKPGSRRRRSYSRSRSHSRSR-------SRSRHSRKSRSRSGSSKSSHSKSRSRSRSGS 226
+D G R R+ + R R + R R R+ + R + R R R
Sbjct: 47 KDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR--------HRKRDRHRERQ 98
Query: 227 RSRSKSRSRSQSRSRSK-KEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGK 285
R R K R R R R + +EK R+ KE+ R + R + D E+ + D K
Sbjct: 99 RDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRD-AEK 157
Query: 286 PKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLR---------QSRSRSRS 336
+ R R + + R+R +ER E+ ++ R R +EK + + R R R
Sbjct: 158 ERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERE 217
Query: 337 KGGSRSRSRSRSKSKDKRKGRKRSREESRSRSR-SRSKSERSRKRGSKRDSKAGSSKKKK 395
R R + +D+++ +R RE+ R R S ++ER ++R +RD +++K
Sbjct: 218 TETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQK 277
Query: 396 KED--TDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPN 453
+ + TDR + R R ER+ + +RE + + R R R +
Sbjct: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDR 337
Query: 454 LPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
R R + R R++ R R R R R R
Sbjct: 338 EKERERKRKRQTEMDRERNRQTGREGRRQAERERERERER 377
Score = 119 bits (297), Expect = 8e-27
Identities = 74/316 (23%), Positives = 138/316 (43%), Gaps = 29/316 (9%)
Query: 192 SRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPS 251
SR R S+ S + R + K + R R+R R R + + +++ + K+E+ R
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86
Query: 252 KEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEE 311
+ + R R + R K +++ ++ R + + K R+R +ER E
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDR---------------ERDRQREKERNRQKERERET 131
Query: 312 EKRGSVSRGR----SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSR 367
E+ G R R +E+ ++ + R + R R R +++ K + R+++R+E R R
Sbjct: 132 EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRER 191
Query: 368 SRSRSK--------SERSRKRGSKRDSKAGSSKKKKKE-DTDRSQSRSPSRSVSKEREHA 418
R R K SER R+R +R+++ + +K++ + + DR + R ERE A
Sbjct: 192 ERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERA 251
Query: 419 KSESSQREGRGESE-NAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSR 477
++R+ E E + +++ R + R + R R + R R + R R
Sbjct: 252 SERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311
Query: 478 SASRSPSRSRSRSHSR 493
+R R R R R
Sbjct: 312 ERNRKRERERERERER 327
Score = 113 bits (282), Expect = 5e-25
Identities = 79/339 (23%), Positives = 137/339 (40%), Gaps = 8/339 (2%)
Query: 158 EKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSH-SRSRSRSRHSRKSRSRSGSSKSSHS 216
E+ TE N +K R E RR R R + + + R R + R R +++
Sbjct: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK 225
Query: 217 KSRSRSRSGSRSRSKSRSRSQSRSR-SKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEE 275
+ R R R + R + R R S++E R +E+ R R + + + + Q +
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDR 285
Query: 276 KIQNNDN----VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSR 331
K Q + + R R + + ++R R +ER E E+ R +EK + R
Sbjct: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR 345
Query: 332 SRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSS 391
R R+R R + + R+R RE R +R R + ER R R +++ + +
Sbjct: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTE 405
Query: 392 KKKK-KEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKS 450
K + + +T++ + R R + RE + Q+ + E Q R R RS
Sbjct: 406 KDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYV 465
Query: 451 KPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
P P +RS + R R +S+ P + +R
Sbjct: 466 NPP-PRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTR 503
Score = 110 bits (276), Expect = 2e-24
Identities = 94/418 (22%), Positives = 162/418 (38%), Gaps = 29/418 (6%)
Query: 68 EHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQA 127
E R R+G G R G R R + R R + K+ R+
Sbjct: 126 ERERETEREGERGRDRQTDGQRERERQRDAEKERE--RQTDRERQRQTERNRQKEREREK 183
Query: 128 GEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSR 187
+ + R+ E E +S+ R E+ TE + R+R R
Sbjct: 184 NRQERRERERQREKENKTED-RHSERGRERERERETETE------------TERKRQTDR 230
Query: 188 SRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRS---KSRSRSQSRSRSKK 244
R R R R + R R+ ++ K R R R R R K R R R R ++
Sbjct: 231 ERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
Query: 245 -EKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSR 303
E+ R +++ R R + R++ +++ E+ + + + R R + K + R R
Sbjct: 291 TERDRETERKRERQRERERERERNRKRERERERERERE-----RQRETERDREKERERKR 345
Query: 304 SQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS-RSRSKSKDKRKGRKRSRE 362
++ ++ E+ R ++ + R R R + +R R R R + +D++K R+R E
Sbjct: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTE 405
Query: 363 ESRSRSRSRSKS-ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK-- 419
+ R R K ER + R S+R + G ++K+K +R + R R ++R+ +
Sbjct: 406 KDRDGQRETEKQREREKDRESERGRERGREREKQK-GRERDRERQTDRQAGRQRKRSTLY 464
Query: 420 SESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSR 477
R R + N+ TR +S P S + A +R R R R
Sbjct: 465 VNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRR 522
Score = 50.8 bits (120), Expect = 3e-06
Identities = 29/153 (18%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Query: 342 SRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDR 401
SR R S+ +R+G ++ +++ R ER+R++ +R + ++++ +R
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGDDR-----ERNRQKERERRREKRQTERETDRKRER 81
Query: 402 SQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSR 461
+ + R + RE + +RE + + E ++ R+R + + R R
Sbjct: 82 RREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDR 141
Query: 462 SKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
+ R R + + R R R R R+
Sbjct: 142 QTDGQRERERQRDAEKERERQTDRERQRQTERN 174
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 127 bits (318), Expect = 3e-29
Identities = 113/348 (32%), Positives = 175/348 (50%), Gaps = 55/348 (15%)
Query: 191 HSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRS------KK 244
H ++R+ +R S +S S G + +K ++ RS SRS+ ++R RS + K+
Sbjct: 151 HEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKE 210
Query: 245 EKSRSPSKEKSRSRSHSAGKSRSKSKDQAEE------KIQNNDNVGKPKSRSPSRHKSKS 298
+ +RS SKE+ +S+S S RSKS+DQA + + ++ + +G K+RSP+ K K
Sbjct: 211 KTTRSKSKERKKSKSPS---KRSKSQDQARKSKSPTLRRRSQEKIG--KARSPTDDKVKI 265
Query: 299 KSRSRSQERR----VEEEK---RGSVS------RGRSQEKSLRQSRSRSRSKGGSRSRSR 345
+ +S+S++R+ + E + RG S RG+S+++ R +S+ + +
Sbjct: 266 EDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKP 325
Query: 346 SRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSR 405
+S SKD G+ E+RS SR +S + R K K+ S+ D QS+
Sbjct: 326 IKSPSKDASSGK-----ENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSK 380
Query: 406 SPSRSVSKEREHAKSESSQREGRGESENAGTNQETR-------SRSRSNSKSKPNLPSES 458
SPSR++S R AKS S +R+ R ++ TR R RS S N S +
Sbjct: 381 SPSRTLSPGR-RAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPT 439
Query: 459 RSRSKSASKTRSRS---KSRS-RSASRSP--------SRSRSRSHSRS 494
R RS+S + RSRS +SRS R SRSP SRSR R SRS
Sbjct: 440 RRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRS 487
Score = 116 bits (291), Expect = 4e-26
Identities = 115/344 (33%), Positives = 167/344 (48%), Gaps = 38/344 (11%)
Query: 169 KIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRH-SRKSRSRSG----SSKSSHSKSRSRSR 223
K+ LV++K +++R S SRS+ R+RH S K +S+ G K++ SKS+ R +
Sbjct: 170 KLELVDNKITTKKR-------SKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKK 222
Query: 224 SGSRS-RSKSRSRSQS--------RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAE 274
S S S RSKS+ +++ RS+ K K+RSP+ +K + S K R KS E
Sbjct: 223 SKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINE 282
Query: 275 EKIQNNDNVGKPKSRSPSRHKSKSKS-RSRSQER---RVEEEKRGSVSRGRSQEKSL-RQ 329
+ ++ GK KSRSP + KSK RSRS+ER R E +K + S++ S ++
Sbjct: 283 SRSRDR---GK-KSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKE 338
Query: 330 SRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAG 389
+RS SR G S R K +DK +RSR + RS+ SR R +K+
Sbjct: 339 NRSPSRRPGRSPKRRSLSPKPRDK---SRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSR 395
Query: 390 SSKKKKKEDTDR---SQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRS 446
S ++K++E R S P + RE +K S R + R RSRS
Sbjct: 396 SLERKRREPERRRLSSPRTRPRDDILSRRERSKDASP--INRWSPTRRRSRSPIRRRSRS 453
Query: 447 NSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRS 490
+ + SRS + RSRS+ R RS SR R RSRS
Sbjct: 454 PLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRS 497
Score = 103 bits (256), Expect = 5e-22
Identities = 103/328 (31%), Positives = 154/328 (46%), Gaps = 32/328 (9%)
Query: 173 VEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSR-SRSGSRSRSK 231
+EDK S+ R+ S + SRSR R + SR G SK S+S+ R S+ + K
Sbjct: 265 IEDKSKSKDRKK-SPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEK 323
Query: 232 SRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
+S S+ S +++RSPS+ RS + + + K + ND K +S+SP
Sbjct: 324 KPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSK-QSKSP 382
Query: 292 SRHKS---KSKSRSRSQERRVEEEKRGSVSRGRSQEKSL-------------RQSRSRSR 335
SR S ++KSRS ++RR E +R S R R ++ L R S +R R
Sbjct: 383 SRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRR 442
Query: 336 SKGGSRSRSRS---RSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSK 392
S+ R RSRS RS+S +R R R+ R RSRSR + RSR RG +R S+
Sbjct: 443 SRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGR-RSRSRLR-RRSRSRGGRR----RRSR 496
Query: 393 KKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKP 452
K KED + S S + E+E + S+ + + E E+ E R R K
Sbjct: 497 SKVKEDKFKG---SLSEGMKVEQE-SSSDDNLEDFDVEEEDEEALIEQRRIQRQAIVQKY 552
Query: 453 NLPSESRSRSKSASKTRSRSKSRSRSAS 480
+E + S + + +S +R+RS S
Sbjct: 553 KYLAEDSNMSVPSEPSSPQSSTRTRSPS 580
Score = 99.0 bits (245), Expect = 9e-21
Identities = 91/311 (29%), Positives = 153/311 (49%), Gaps = 32/311 (10%)
Query: 170 IRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRS------- 222
I +V++K + + +S+S S+ +RKS+S + +S ++RS
Sbjct: 205 IEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVK 264
Query: 223 ---RSGSRSRSKSRSRSQSRSRSKKEKSRSP------SKEKSRSRSHSAGKSRSKS-KDQ 272
+S S+ R KS ++SRSR + +KSRSP SK++ RSRS RS++ K++
Sbjct: 265 IEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDR-RSRSKERKSKRSETDKEK 323
Query: 273 AEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRS 332
K + D ++RSPSR +S R RS + ++ R S S + +S +QS+S
Sbjct: 324 KPIKSPSKDASSGKENRSPSRRPGRSPKR-RSLSPKPRDKSRRSRSPLLNDRRS-KQSKS 381
Query: 333 RSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSK 392
SR+ R R++SRS + +R+ +R R+R R S R R + + ++ ++
Sbjct: 382 PSRTLSPGR-RAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTR 440
Query: 393 KKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKP 452
++ + R +SRSP R R +S S +R RG + +RSR R S+S+
Sbjct: 441 RRSRSPI-RRRSRSPLRRSRSPRR--RSRSPRRRDRG--------RRSRSRLRRRSRSRG 489
Query: 453 NLPSESRSRSK 463
SRS+ K
Sbjct: 490 GRRRRSRSKVK 500
Score = 90.1 bits (222), Expect = 4e-18
Identities = 84/330 (25%), Positives = 149/330 (45%), Gaps = 41/330 (12%)
Query: 192 SRSRSRSRHSR----KSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKS 247
S +S+++HSR K + RS K HS + + + + + + ++
Sbjct: 32 SEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKKHKRKEIIDASDKEG 91
Query: 248 RSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKS------------------- 288
SP+K +++ + + K + + ++ N GK +S
Sbjct: 92 MSPAK-RTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGLILQGYESGSEEEGEI 150
Query: 289 RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRS---RSKGGSR--SR 343
+R+ ++S +RS S + ++E ++ RS+ +S ++R RS +SKGG
Sbjct: 151 HEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKE 210
Query: 344 SRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQ 403
+RSKSK+++K + S+ +SKS R+R ++ KA S K + D+S+
Sbjct: 211 KTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSK 270
Query: 404 S----RSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESR 459
S +SP + S+ R+ K S + RG+S ++ RSRS+ KSK + + +
Sbjct: 271 SKDRKKSPIINESRSRDRGKKSRSPVDLRGKS------KDRRSRSKER-KSKRSETDKEK 323
Query: 460 SRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
KS SK S K +RS SR P RS R
Sbjct: 324 KPIKSPSKDASSGK-ENRSPSRRPGRSPKR 352
Score = 81.3 bits (199), Expect = 2e-15
Identities = 80/315 (25%), Positives = 140/315 (44%), Gaps = 28/315 (8%)
Query: 194 SRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPS-- 251
+ ++S + + S KS + ++ S S+++ + + + RSK +K + S
Sbjct: 4 AETQSLREQPEMEDANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEE 63
Query: 252 -KEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVE 310
K+K H K + K A +K + + K + + K R+ +
Sbjct: 64 DKDKKHKHKHKHKKHKRKEIIDASDK-EGMSPAKRTKLDDLALLEDLEKQRALIKAELDN 122
Query: 311 EEKRGSVSRGRS------QEKSLRQSRSRSRSKGGSRSRSRSRS-KSK-----DKRKGRK 358
E G V G + S + +++ G+RS +RS S K K +K +K
Sbjct: 123 ELMEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKK 182
Query: 359 RSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHA 418
RS+ RS+ R+R +S++ + +G K +++ K KE R +S+SPS+ SK ++ A
Sbjct: 183 RSKS--RSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKE---RKKSKSPSKR-SKSQDQA 236
Query: 419 KSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRS 478
+ S R E G ++RS ++ K K S+S+ R KS SRS+ R +
Sbjct: 237 RKSKSPTLRRRSQEKIG-----KARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKK 291
Query: 479 ASRSPSRSRSRSHSR 493
SRSP R +S R
Sbjct: 292 -SRSPVDLRGKSKDR 305
Score = 70.5 bits (171), Expect = 3e-12
Identities = 81/290 (27%), Positives = 125/290 (43%), Gaps = 53/290 (18%)
Query: 166 NGRKIRLVEDKPG-SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRS 224
+G++ R +PG S +RRS S + R +SR SR SK S S SR+ S
Sbjct: 335 SGKENRSPSRRPGRSPKRRSLS-----PKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPG 389
Query: 225 GSRSRSKSRSRSQSRSRSKKEKSRSPS--------KEKSRSRSHSAGKSRSKSKDQAEEK 276
R+KSRS + R ++ + SP + RS+ S S ++ ++
Sbjct: 390 ---RRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSP 446
Query: 277 IQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS 336
I+ +SRSP R RSRS RR RGR LR+ RSRS
Sbjct: 447 IRRRSRSPLRRSRSPRR-------RSRSPRRR---------DRGRRSRSRLRR---RSRS 487
Query: 337 KGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKK 396
+GG R RSRS+ K +DK KG S S+ + + S D+ +++
Sbjct: 488 RGGRRRRSRSKVK-EDKFKG-------------SLSEGMKVEQESSSDDNLEDFDVEEED 533
Query: 397 EDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRS 446
E+ Q R +++ ++ ++ +S+ SE + TR+RS S
Sbjct: 534 EEALIEQRRIQRQAIVQKYKYLAEDSNMSV---PSEPSSPQSSTRTRSPS 580
Score = 60.1 bits (144), Expect = 5e-09
Identities = 67/241 (27%), Positives = 109/241 (45%), Gaps = 21/241 (8%)
Query: 171 RLVEDKPGSRRRRSYSRSRSHSRSRSRSRH---SRKSRSRSGSSKSSHSKSRSRSRSGSR 227
R + + R+RR R R S R+R R SR+ RS+ S + S +R RSRS R
Sbjct: 390 RRAKSRSLERKRREPERRRLSS-PRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIR 448
Query: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEKS--RSRSHSAGKSRSKSKDQAEEKIQNNDNVGK 285
RS+S R RSRS + +SRSP + RSRS +SRS+ + + + ++ K
Sbjct: 449 RRSRSPLR---RSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFK 505
Query: 286 PKSRSPSRHKSKSKSRSRSQERRVEEE-KRGSVSRGRSQEKSLRQ---------SRSRSR 335
+ + +S S ++ VEEE + + + R Q +++ Q + S
Sbjct: 506 GSLSEGMKVEQESSSDDNLEDFDVEEEDEEALIEQRRIQRQAIVQKYKYLAEDSNMSVPS 565
Query: 336 SKGGSRSRSRSRSKSKDKRKGRKRS--REESRSRSRSRSKSERSRKRGSKRDSKAGSSKK 393
+S +R+RS S D R + +E R + S +++ + GSS+K
Sbjct: 566 EPSSPQSSTRTRSPSPDDILERVAADVKEYERENVDTFEASVKAKHNLMTVEQNNGSSQK 625
Query: 394 K 394
K
Sbjct: 626 K 626
Score = 57.4 bits (137), Expect = 3e-08
Identities = 58/208 (27%), Positives = 90/208 (43%), Gaps = 28/208 (13%)
Query: 164 EVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRS--RHSRKSRSRSGSSKSSHSKSRSR 221
++ R+ R + P +R + RSRS R RSRS R SR R RS S + RSR
Sbjct: 419 DILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSR 478
Query: 222 SRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEE------ 275
SR RSRS+ R +SRS+ K++K + E + S+ + D EE
Sbjct: 479 SRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALI 538
Query: 276 ---KIQNNDNVGKPK----------SRSPSRHKSKSKSRSRSQE-------RRVEEEKRG 315
+IQ V K K PS +S +++RS S + V+E +R
Sbjct: 539 EQRRIQRQAIVQKYKYLAEDSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERE 598
Query: 316 SVSRGRSQEKSLRQSRSRSRSKGGSRSR 343
+V + K+ + ++ G S+ +
Sbjct: 599 NVDTFEASVKAKHNLMTVEQNNGSSQKK 626
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 120 bits (300), Expect = 4e-27
Identities = 82/256 (32%), Positives = 122/256 (47%), Gaps = 13/256 (5%)
Query: 172 LVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSK 231
L +K R + +S R+ H +SRSRS K R G + RS+
Sbjct: 11 LAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERK------RKSDNEGRKHRSR 64
Query: 232 SRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
SRS+ R SK + S+ E+ + HS+ K R + +N ++ K K R
Sbjct: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSS-----ENGEDRHKRKERKS 119
Query: 292 SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS-KS 350
SR +S S+SRSR + R +R SR RS+E+ +SRSR R K SRSR R R +S
Sbjct: 120 SRGRSHSRSRSRERRHRSRSRERKK-SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRS 178
Query: 351 KDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRS 410
+ + + R R R SRSR+RSRS+ + R +R S++ S R+ + +
Sbjct: 179 RSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEA 238
Query: 411 VSKEREHAKSESSQRE 426
+++ E AK QRE
Sbjct: 239 LARRLERAKKLQEQRE 254
Score = 114 bits (286), Expect = 2e-25
Identities = 84/245 (34%), Positives = 122/245 (49%), Gaps = 36/245 (14%)
Query: 244 KEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSR 303
K+K +S R+ H +SRS+S+ E+ + +DN G+ K +SRSR
Sbjct: 22 KKKEQSEVSVSPRASKHHYSRSRSRSR----ERKRKSDNEGR-----------KHRSRSR 66
Query: 304 SQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREE 363
S+E R E K S + +S+E + + S KG R S + + KRK RK SR
Sbjct: 67 SKEGRRHESKDKSSKKHKSEEHN---DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 123
Query: 364 SRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESS 423
S SRSRSR + RSR R ++K+ RS+ R SRS S+ER+ ++S S
Sbjct: 124 SHSRSRSRERRHRSRSR-------------ERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
Query: 424 QREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSP 483
+R+ R S + +RSR R ++S+ S SR R K K R S+S SR+ S P
Sbjct: 171 ERKRRIRSRS-----RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPP 225
Query: 484 SRSRS 488
R R+
Sbjct: 226 FRGRN 230
Score = 103 bits (257), Expect = 4e-22
Identities = 73/235 (31%), Positives = 118/235 (50%), Gaps = 32/235 (13%)
Query: 180 RRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKS---------SHSKSRSRSRSGS---- 226
R+R+S + R H RSRSRS+ R+ S+ SSK HS + R R S
Sbjct: 50 RKRKSDNEGRKH-RSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENG 108
Query: 227 --------RSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQ 278
R S+ RS S+SRSR ++ +SRS ++KSRSRS KSRS+S+++ + + +
Sbjct: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 168
Query: 279 NNDNVGK--PKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS 336
+ + + +SRS SRH+ +++SRSR++ R + +KR EK R SRS SR+
Sbjct: 169 SRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR--------IEKPRRFSRSLSRT 220
Query: 337 KGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSS 391
R R+ + + R+ R + R + E+ +++ + G S
Sbjct: 221 PSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGS 275
Score = 94.7 bits (234), Expect = 2e-19
Identities = 69/189 (36%), Positives = 100/189 (52%), Gaps = 9/189 (4%)
Query: 313 KRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS-KSKDKRKGRK-RSREESRSRSRS 370
++ S R + +E+S R+ SRSRSRSR K K +GRK RSR S+ R
Sbjct: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRH 73
Query: 371 RSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQS-----RSPSRSVSKEREHAKSESSQR 425
SK + S+K S+ + S K +E + S++ + R S+ R H++S S +R
Sbjct: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 133
Query: 426 EGRGES-ENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPS 484
R S E + +R R +S S+S+ S SRSR + + RSRS+SRSR R+ S
Sbjct: 134 RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERK-RRIRSRSRSRSRHRHRTRS 192
Query: 485 RSRSRSHSR 493
RSR+RS SR
Sbjct: 193 RSRTRSRSR 201
Score = 93.2 bits (230), Expect = 5e-19
Identities = 69/178 (38%), Positives = 89/178 (50%), Gaps = 19/178 (10%)
Query: 323 QEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGS 382
++K QS + SRSRS+S++++ RK E + RSRSRSK G
Sbjct: 20 RDKKKEQSEVSVSPRASKHHYSRSRSRSRERK--RKSDNEGRKHRSRSRSKE------GR 71
Query: 383 KRDSKAGSSKKKKKED-TDRSQSRSPSR-----SVSKEREHAKSESSQREGRGESENAGT 436
+ +SK SSKK K E+ D+ S R S + E H + E GR S +
Sbjct: 72 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 131
Query: 437 NQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
+ RSRSR KS+ S SR R KS S++R R KSRSRS R R RSRS SRS
Sbjct: 132 ERRHRSRSRERKKSR----SRSRERKKSRSRSRERKKSRSRSRERK-RRIRSRSRSRS 184
Score = 46.6 bits (109), Expect = 5e-05
Identities = 41/134 (30%), Positives = 59/134 (44%), Gaps = 26/134 (19%)
Query: 379 KRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQ 438
+R K + KKKE ++ S S S+ +++S S RE + +S+N G +
Sbjct: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASK-----HHYSRSRSRSRERKRKSDNEG--R 59
Query: 439 ETRSRSRS------NSKSKPNLPSES-------------RSRSKSASKTRSRSKSRSRSA 479
+ RSRSRS SK K + +S R R S+ R K + R +
Sbjct: 60 KHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS 119
Query: 480 SRSPSRSRSRSHSR 493
SR S SRSRS R
Sbjct: 120 SRGRSHSRSRSRER 133
Score = 35.8 bits (81), Expect = 0.092
Identities = 19/64 (29%), Positives = 30/64 (46%)
Query: 430 ESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
++E G E S R K + + R+ S++RSRS+ R R + + RSR
Sbjct: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
Query: 490 SHSR 493
S S+
Sbjct: 65 SRSK 68
Score = 33.5 bits (75), Expect = 0.46
Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Query: 398 DTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSE 457
DT+R +P ++ S +R+ K +S S++ + +RSR R
Sbjct: 5 DTERD-GLAPEKT-SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR 62
Query: 458 SRSRSKSASKTRSRSKSRSRSAS 480
SRSRSK + S+ KS + S
Sbjct: 63 SRSRSKEGRRHESKDKSSKKHKS 85
Score = 30.8 bits (68), Expect = 3.0
Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 8/83 (9%)
Query: 420 SESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRS--------R 471
+ ++R+G + + + + +S + + + SRSRS+S + R R
Sbjct: 3 ASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR 62
Query: 472 SKSRSRSASRSPSRSRSRSHSRS 494
S+SRS+ R S+ +S +S
Sbjct: 63 SRSRSKEGRRHESKDKSSKKHKS 85
>gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]
Length = 238
Score = 113 bits (283), Expect = 3e-25
Identities = 103/281 (36%), Positives = 132/281 (46%), Gaps = 69/281 (24%)
Query: 3 RVYIGRLSYQARERDVERFFKGYGKILEVDLKN---GYGFVEFDDLRDADDAVYELNGKD 59
+VY+G L A + ++ER F YG + V + G+ FVEF+D RDA+DAV L+GK
Sbjct: 12 KVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKV 71
Query: 60 LCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQD 119
+CG RV VE + G RRS D+ PP R + D
Sbjct: 72 ICGSRVRVELSTGMP--------------RRSRFDR--PPARRPF--------------D 101
Query: 120 LKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGS 179
D + GE K + YS +R+ + + S
Sbjct: 102 PNDRCYECGE----------KGHYAYDCHRYSRRRRSRSR---------------SRSHS 136
Query: 180 RRR-RSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSG---------SRSR 229
R R R YSRSRS SR R RSR + RSRS S + S S S RSRSG S SR
Sbjct: 137 RSRGRRYSRSRSRSRGR-RSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSR 195
Query: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSK 270
S+SRSRS SR RS + KSRSPS ++SRS S S +S S +
Sbjct: 196 SRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRSASPER 236
Score = 77.4 bits (189), Expect = 3e-14
Identities = 71/233 (30%), Positives = 101/233 (43%), Gaps = 6/233 (2%)
Query: 103 EYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDG 162
E ++ V NL + +L+ G + + +EF D + A+ LDG
Sbjct: 10 ETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDG 69
Query: 163 TEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRS 222
+ G ++R VE G RR + R + R + R RS
Sbjct: 70 KVICGSRVR-VELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRS 128
Query: 223 RSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDN 282
RS SRS S+SR R SRSRS+ RS S RSRS S +SRS S + ++
Sbjct: 129 RSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASL----RRSRSGSI 184
Query: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSR 335
G +SPSR +S+S+S SR + R + + S R RS S R+S S R
Sbjct: 185 KGSRYFQSPSRSRSRSRSISRPRSSR-SKSRSPSPKRSRSPSGSPRRSASPER 236
Score = 67.8 bits (164), Expect = 2e-11
Identities = 57/148 (38%), Positives = 73/148 (49%), Gaps = 35/148 (23%)
Query: 328 RQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSK 387
R+ RSRSRS+ SRSR R S+S+ + +GR R S S RSRS S R + S R S+
Sbjct: 124 RRRRSRSRSRSHSRSRGRRYSRSRSRSRGR---RSRSASPRRSRSISLRRSRSASLRRSR 180
Query: 388 AGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSN 447
+GS K + + S+SRS SRS+S+ R +RS+SRS
Sbjct: 181 SGSIKGSRYFQSP-SRSRSRSRSISRPR-----------------------SSRSKSRS- 215
Query: 448 SKSKPNLPSESRSRSKSASKTRSRSKSR 475
PS RSRS S S RS S R
Sbjct: 216 -------PSPKRSRSPSGSPRRSASPER 236
Score = 67.8 bits (164), Expect = 2e-11
Identities = 55/134 (41%), Positives = 68/134 (50%), Gaps = 23/134 (17%)
Query: 353 KRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVS 412
+R+ R RSR SRSR R S+S RSR RG RS+S SP RS S
Sbjct: 125 RRRSRSRSRSHSRSRGRRYSRS-RSRSRGR------------------RSRSASPRRSRS 165
Query: 413 KEREHAKSESSQREGRGESENAGTNQE-TRSRSRSNSKSKPNLPSESRSRSKSASKTRSR 471
++S S +R G + + Q +RSRSRS S S+P SRS+S+S S RSR
Sbjct: 166 ISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSRSRSISRPR---SSRSKSRSPSPKRSR 222
Query: 472 SKSRSRSASRSPSR 485
S S S S SP R
Sbjct: 223 SPSGSPRRSASPER 236
Score = 66.6 bits (161), Expect = 5e-11
Identities = 56/128 (43%), Positives = 70/128 (54%), Gaps = 13/128 (10%)
Query: 289 RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGR-SQEKSLRQSRSRSRSKGGSRSRSRSR 347
R R +S+S+SRS S+ R + S SRGR S+ S R+SRS S + S S RSR
Sbjct: 121 RYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRSR 180
Query: 348 SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
S S KG + + SRSRSRSRS S R R S+ S++ S K+ RS S SP
Sbjct: 181 SGSI---KGSRYFQSPSRSRSRSRSIS---RPRSSRSKSRSPSPKRS------RSPSGSP 228
Query: 408 SRSVSKER 415
RS S ER
Sbjct: 229 RRSASPER 236
Score = 52.8 bits (125), Expect = 7e-07
Identities = 53/151 (35%), Positives = 70/151 (46%), Gaps = 24/151 (15%)
Query: 358 KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREH 417
+RSR + R ++R + G K + ++ RS+SRS S S S+ R +
Sbjct: 87 RRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRR---RSRSRSRSHSRSRGRRY 143
Query: 418 AKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSA-------SKTRS 470
++S S R R S + RSRS S + S RSRS S S +RS
Sbjct: 144 SRSRSRSRGRRSRSASP-------RRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRS 196
Query: 471 RSKSR-------SRSASRSPSRSRSRSHSRS 494
RS+SR SRS SRSPS RSRS S S
Sbjct: 197 RSRSRSISRPRSSRSKSRSPSPKRSRSPSGS 227
>gi|16905517 FUS interacting protein (serine-arginine rich) 1
isoform 2 [Homo sapiens]
Length = 262
Score = 111 bits (278), Expect = 1e-24
Identities = 81/273 (29%), Positives = 137/273 (50%), Gaps = 40/273 (14%)
Query: 4 VYIGRLSYQARERDVERFFKGYGKILEVDLK--------NGYGFVEFDDLRDADDAVYEL 55
+++ ++ R D+ R F YG I++V + G+ +V+F+D+RDA+DA++ L
Sbjct: 12 LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
Query: 56 NGKDLCGERVIVEHARGPRRDGSYGSGRSGYG-YRRSGRDKYGPPTRTEYRLIVENLSSR 114
+ K +CG ++ ++ A+G R+ + + G Y S D Y R+ R S
Sbjct: 72 DRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRS 131
Query: 115 CSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVE 174
S+ +Y R + R++ S+SD R
Sbjct: 132 RSFD--YNYRRSYSPRNSRPTGRPRRSR------SHSDNDRF------------------ 165
Query: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
R RS+SRS+S+SRSRS+S+ ++ +++S S +SH+K+R S++ S++ KS S
Sbjct: 166 ----KHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGS 221
Query: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRS 267
R + SR KKE RS S+ +S+SRS S +SRS
Sbjct: 222 RYEKESR-KKEPPRSKSQSRSQSRSRSKSRSRS 253
Score = 98.2 bits (243), Expect = 2e-20
Identities = 90/290 (31%), Positives = 137/290 (47%), Gaps = 39/290 (13%)
Query: 95 KYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYA----DAHKGR-KNEGVIEFVS 149
+Y P T L V N++ +DL+ + G + D + R + ++F
Sbjct: 3 RYLRPPNTS--LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60
Query: 150 YSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSG 209
D + AL LD + GR+I ++ G R+ + +++ S SR+ R R
Sbjct: 61 VRDAEDALHNLDRKWICGRQIE-IQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYR-- 117
Query: 210 SSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKS 269
RSRSRS R RS+SRS + RS ++ P+ RSRSHS
Sbjct: 118 ---------RSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHS-------- 160
Query: 270 KDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQ 329
+ND K ++RS SR KS S+SRS+SQ ++ E K S SR S K+
Sbjct: 161 ---------DNDRF-KHRNRSFSRSKSNSRSRSKSQPKK--EMKAKSRSRSASHTKTRGT 208
Query: 330 SRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRK 379
S++ S++ S SR S+ K+ + + +SR +SRSRS+SRS+S S K
Sbjct: 209 SKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPK 258
Score = 79.7 bits (195), Expect = 6e-15
Identities = 55/171 (32%), Positives = 90/171 (52%), Gaps = 5/171 (2%)
Query: 328 RQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSK 387
R++ ++ ++K G S SR D+ + R RSR R RSRSRS R+ S R+S+
Sbjct: 90 RKTPNQMKAKEGRNVYSSSRYDDYDRYR-RSRSRSYERRRSRSRSFDYNYRRSYSPRNSR 148
Query: 388 AGSSKKKKKEDTD----RSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSR 443
++ + +D + ++RS SRS S R +KS+ + + ++ +TR
Sbjct: 149 PTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGT 208
Query: 444 SRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
S+++SK+ S S+ RS+S+SRS+S SRS SRSRS + +S
Sbjct: 209 SKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKS 259
Score = 76.3 bits (186), Expect = 6e-14
Identities = 49/136 (36%), Positives = 71/136 (52%), Gaps = 4/136 (2%)
Query: 287 KSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346
+SRS S + +S+SRS R R S GR + R + + S SRS+S
Sbjct: 118 RSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKS 177
Query: 347 RSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGS----SKKKKKEDTDRS 402
S+S+ K + +K + +SRSRS S +K+ + K SK K+GS +KK+ +S
Sbjct: 178 NSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKS 237
Query: 403 QSRSPSRSVSKEREHA 418
QSRS SRS SK R +
Sbjct: 238 QSRSQSRSRSKSRSRS 253
Score = 67.0 bits (162), Expect = 4e-11
Identities = 55/154 (35%), Positives = 83/154 (53%), Gaps = 20/154 (12%)
Query: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358
+SRSRS ERR SR RS + + R+S S S+ R R RSRS S D + +
Sbjct: 118 RSRSRSYERRR--------SRSRSFDYNYRRSYSPRNSRPTGRPR-RSRSHS-DNDRFKH 167
Query: 359 RSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSK-EREH 417
R+R SRS+S SRS+S+ K+ K S++ S+ K T ++ S++ +S S+ E+E
Sbjct: 168 RNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKES 227
Query: 418 AKSESSQREGRGESENAGTNQETRSRSRSNSKSK 451
K E + + + S+ SRSRS S+S+
Sbjct: 228 RKKEPPRSKSQSRSQ---------SRSRSKSRSR 252
Score = 66.6 bits (161), Expect = 5e-11
Identities = 60/197 (30%), Positives = 91/197 (46%), Gaps = 33/197 (16%)
Query: 289 RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRS------RSRSKGGSRS 342
++P++ K+K + R+ R ++ R SR RS E+ +SRS RS S SR
Sbjct: 91 KTPNQMKAK-EGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRP 149
Query: 343 RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
R R R + R S SRS+S S+S S + KKE +S
Sbjct: 150 TGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSR--------------SKSQPKKEMKAKS 195
Query: 403 QSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRS 462
+SRS S H K+ + + +G+ E SR + +SK S+SRS+S
Sbjct: 196 RSRSAS--------HTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSK----SQSRSQS 243
Query: 463 KSASKTRSRSKSRSRSA 479
+S SK+RSRS + +S+
Sbjct: 244 RSRSKSRSRSWTSPKSS 260
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 110 bits (276), Expect = 2e-24
Identities = 122/441 (27%), Positives = 181/441 (41%), Gaps = 35/441 (7%)
Query: 63 ERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKD 122
E ++HA+ + + SGR RR R+K R R I +R
Sbjct: 245 EAEAIKHAKALEEEKAMYSGRRSRRQRREFREK-----RLRGRKISPPSYARRDSPTYDP 299
Query: 123 YMRQAGEVTYADAHKGRK----NEGVIEFV-----SYSDMKRALEKLDGTEVNGRKIRLV 173
Y R E + + R E I F+ S + A + V K
Sbjct: 300 YKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAP 359
Query: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSK-SRSRSRSGSRSRSKS 232
G R+ S R S S S S SR S SRS S SS S+ RSG +RS+S
Sbjct: 360 PQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRS 419
Query: 233 RSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPS 292
RS S+SRSRS++ S+ +SR R HS G SR + + + + +SRS S
Sbjct: 420 RSWSRSRSRSRRY-----SRSRSRGRRHSGGGSRDGHR-YSRSPARRGGYGPRRRSRSRS 473
Query: 293 RHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD 352
+ + R R S S S+ +SL +SRS S S SRSRSRSRS+S
Sbjct: 474 HSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPS 533
Query: 353 KRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKK--KKEDTDRSQSRSPSRS 410
+RE+ + S + E+ +K + G++K K +E ++ +R
Sbjct: 534 PSP----AREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQ 589
Query: 411 VSKEREHAKSESSQREGRGESENAGTN--------QETRSRSRSNSKSKPNLPSESRSRS 462
+++ A+ + Q+E + +E R + + + +SRS S
Sbjct: 590 FKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPS 649
Query: 463 KSASKTRSRSKSRSRSASRSP 483
S+ S S+ RSRS SRSP
Sbjct: 650 PRYSREYSSSRRRSRSRSRSP 670
Score = 108 bits (270), Expect = 1e-23
Identities = 110/308 (35%), Positives = 138/308 (44%), Gaps = 44/308 (14%)
Query: 190 SHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRS 249
S RSR + R R+ R R R RS S S S+SRSRS+ S +
Sbjct: 263 SGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSR---SPT 319
Query: 250 PSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRV 309
P +E+ + S G S ++ A + GKP + P + + R+ S RR
Sbjct: 320 PGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPA--PPQPGGPAPGRNASARRRS 377
Query: 310 EEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSR 369
S S + R S SRS S+ SRSR R + R R RSR SRSRSR
Sbjct: 378 --------SSSSSSSSASRTSSSRSSSRSSSRSR-RGGGYYRSGRHARSRSRSWSRSRSR 428
Query: 370 SRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVS---KEREHAKSESSQRE 426
SR S RSR RG +R S GS + SRSP+R + R ++S S R
Sbjct: 429 SRRYS-RSRSRG-RRHSGGGSRDGHR-------YSRSPARRGGYGPRRRSRSRSHSGDRY 479
Query: 427 GRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRS 486
RG G + SRSRS S S S +RSRS +RSRS S SPS+S
Sbjct: 480 RRG---GRGLRHHSSSRSRS---------------SWSLSPSRSRSLTRSRSHSPSPSQS 521
Query: 487 RSRSHSRS 494
RSRS SRS
Sbjct: 522 RSRSRSRS 529
Score = 100 bits (249), Expect = 3e-21
Identities = 119/391 (30%), Positives = 166/391 (42%), Gaps = 65/391 (16%)
Query: 135 AHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRS 194
A K + E E S SD + +D EV+ ++ + +++ +Y +
Sbjct: 179 AEKPEEEESAAEEESNSDEDEVIPDID-VEVDVDELNQEQVADLNKQATTYGMADGDF-- 235
Query: 195 RSRSRHSRKSRSRSGSSKSSHSKSRSRSR-SGSRSRSKSRSRSQSRSRSKKEK------- 246
R RK + + + K + + ++ SG RSR + R + R R +K
Sbjct: 236 ---VRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARR 292
Query: 247 --------SRSPSKEKSRSRSHSA----------------GKSRSKSKDQAEEKIQNNDN 282
RSPS+ S SRS S G S ++ A +
Sbjct: 293 DSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVT 352
Query: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342
GKP +P + + R+ S RR S S + R S SRS S+ SRS
Sbjct: 353 TGKPP--APPQPGGPAPGRNASARRR--------SSSSSSSSSASRTSSSRSSSRSSSRS 402
Query: 343 RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
R R + R R RSR SRSRSRSR S RSR RG +R S GS +
Sbjct: 403 R-RGGGYYRSGRHARSRSRSWSRSRSRSRRYS-RSRSRG-RRHSGGGSRDGHR------- 452
Query: 403 QSRSPSRSVS---KEREHAKSESSQREGRGESENAGTNQETRSRSRSN-SKSKPNLPSES 458
SRSP+R + R ++S S R RG G + SRSRS+ S S S +
Sbjct: 453 YSRSPARRGGYGPRRRSRSRSHSGDRYRRG---GRGLRHHSSSRSRSSWSLSPSRSRSLT 509
Query: 459 RSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
RSRS S S ++SRS+SRSRS S SPS +R +
Sbjct: 510 RSRSHSPSPSQSRSRSRSRSQSPSPSPAREK 540
Score = 83.6 bits (205), Expect = 4e-16
Identities = 83/261 (31%), Positives = 120/261 (45%), Gaps = 62/261 (23%)
Query: 182 RRSYSRSRSHSRSRSRSRHSRKSRSRS-----GSSKSSHSKSRSRSRSGS-----RSRSK 231
R + SRSRS SRSRSRSR +SRSR G S+ H SRS +R G RSRS+
Sbjct: 413 RHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSR 472
Query: 232 SRS-----------RSQSRSRSKKEKSRSPSKEKS--RSRSHSAG----KSRSKSKDQAE 274
S S R S SRS+ S SPS+ +S RSRSHS +SRS+S+ Q+
Sbjct: 473 SHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSP 532
Query: 275 EKIQNNDNVGKP----------KSRSPSRHKSK--SKSRSRSQER---RVEE--EKRGSV 317
+ + +P K P+ K +K + QE+ R+++ ++
Sbjct: 533 SPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKA 592
Query: 318 SRGRSQEKSLRQSRSRSRSKGGSRSRSRS-RSKSKDKRKGRKR----------------- 359
+ +QEK ++Q R + R+ +R R K +++R+ +
Sbjct: 593 DKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRY 652
Query: 360 SREESRSRSRSRSKSERSRKR 380
SRE S SR RSRS+S R
Sbjct: 653 SREYSSSRRRSRSRSRSPHYR 673
Score = 77.0 bits (188), Expect = 4e-14
Identities = 72/215 (33%), Positives = 107/215 (49%), Gaps = 21/215 (9%)
Query: 178 GSRRRRSYSRSRSHSRSRSRS-----RHSRKSRSRSGSSKS-SHSKSRSRSRSGS----- 226
G RRR SRSRSHS R R RH SRSRS S S S S+S +RSRS S
Sbjct: 464 GPRRR---SRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQ 520
Query: 227 -RSRSKSRSRSQSRSRSKKEKSR---SPS-KEKSRSRSHSAGKSRSKSKDQAEEKIQNND 281
RSRS+SRS+S S S ++++ +R SP+ EK + +AGK +K + + +
Sbjct: 521 SRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKL 580
Query: 282 NVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSR 341
+ K +R K ++ + QE E ++R R +++ +++ R + +
Sbjct: 581 RMQKALNRQFKADKKAAQEKMIQQEH--ERQEREDELRAMARKIRMKERERREKEREEWE 638
Query: 342 SRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSER 376
+ +S+S R R+ S RSRSRSRS R
Sbjct: 639 RQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYR 673
Score = 46.2 bits (108), Expect = 7e-05
Identities = 72/293 (24%), Positives = 114/293 (38%), Gaps = 77/293 (26%)
Query: 62 GERVIVEHARGPRRDGSYGSGR-------SGYGYRRSGRD-KYGPPTRTEYRLIVENLSS 113
G R ++R P R G YG R SG YRR GR ++ +R S
Sbjct: 446 GSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSR-----------S 494
Query: 114 RCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLV 173
R SW R +T + +H
Sbjct: 495 RSSWSLSPSRSR---SLTRSRSH------------------------------------- 514
Query: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR 233
P R RS SRS+S S S +R + +R + S + K ++ + +G+ ++ K
Sbjct: 515 SPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGA-AKPKLT 573
Query: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
+ + + R +K +R +K ++ K Q E+ + D + R+ +R
Sbjct: 574 PQEKLKLRMQKALNRQFKADKK--------AAQEKMIQQEHERQEREDEL-----RAMAR 620
Query: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346
K + K R R ++ R E E++ S +S+ S R SR S S+ SRSRSRS
Sbjct: 621 -KIRMKERERREKEREEWERQYS---RQSRSPSPRYSREYSSSRRRSRSRSRS 669
Score = 30.4 bits (67), Expect = 3.9
Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 7/65 (10%)
Query: 158 EKLDGTEVNGRKIRLVEDKPGSRRRRSY-------SRSRSHSRSRSRSRHSRKSRSRSGS 210
E+ D RKIR+ E + + R + SRS S SR S R+SRSRS S
Sbjct: 610 EREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669
Query: 211 SKSSH 215
H
Sbjct: 670 PHYRH 674
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 108 bits (270), Expect = 1e-23
Identities = 95/252 (37%), Positives = 126/252 (50%), Gaps = 42/252 (16%)
Query: 189 RSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSR 248
R HSRSRSRSR R S S H +SRSRSR RS SKSRSR +S+S ++ R
Sbjct: 246 RRHSRSRSRSRRRRTP------SSSRHRRSRSRSRR--RSHSKSRSRRRSKSPRRR---R 294
Query: 249 SPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERR 308
S S+E+ R RS S K+R K K+ E+K PKS S +R +SRS S+ERR
Sbjct: 295 SHSRERGR-RSRSTSKTRDKKKEDKEKKRSKT----PPKSYSTAR-----RSRSASRERR 344
Query: 309 VEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRS 368
+R S S RS +K R SRS R K K K K ++RSR+E R
Sbjct: 345 ----RRRSRSGTRSPKKPRSPKRKLSRSPS-----PRRHKKEKKKDKDKERSRDE---RE 392
Query: 369 RSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK--------- 419
RS SK ++S+ + R+ K+ S K K+ D + S +++E K
Sbjct: 393 RSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKT 452
Query: 420 SESSQREGRGES 431
E S +G G+S
Sbjct: 453 KECSVEKGTGDS 464
Score = 103 bits (258), Expect = 3e-22
Identities = 83/232 (35%), Positives = 118/232 (50%), Gaps = 28/232 (12%)
Query: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKS-- 232
DK +RR +SRSRS SR R SR RSRS S + SHSKSRSR RS S R +S
Sbjct: 240 DKKEEKRR--HSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHS 297
Query: 233 -----RSRSQSRSRSKK----EKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
RSRS S++R KK EK RS + KS S +A +SRS S+++ + ++
Sbjct: 298 RERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYS---TARRSRSASRERRRRRSRSGTRS 354
Query: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSR 343
K K RSP R S+S S RR ++EK+ + RS+++ R + + +SK + R
Sbjct: 355 PK-KPRSPKRKLSRSPS-----PRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDR 408
Query: 344 SRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKK 395
R KD ++ + EE + + K E K+ + GS K K+
Sbjct: 409 ERKSESDKDVKQVTRDYDEEEQGYDSEKEKKE------EKKPIETGSPKTKE 454
Score = 97.4 bits (241), Expect = 3e-20
Identities = 72/252 (28%), Positives = 122/252 (48%), Gaps = 17/252 (6%)
Query: 202 RKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHS 261
R+++S ++ K R S SRSRS+ R R+ S SR ++ +SRS R RSHS
Sbjct: 227 REAQSLISAAIEPDKKEEKRRHSRSRSRSRRR-RTPSSSRHRRSRSRS------RRRSHS 279
Query: 262 AGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHK---SKSKSRSRSQERRVEEEKRGSVS 318
+SR +SK + + + + +S S +R K K K RS++ + +R S
Sbjct: 280 KSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARR---S 336
Query: 319 RGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSR 378
R S+E+ R+SRS +RS RS R S+S R+ +K E+ + + + RS+ ER R
Sbjct: 337 RSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKK---EKKKDKDKERSRDERER 393
Query: 379 KRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQ 438
K+ SK +++K ++D+ + +R +E + SE ++E + E
Sbjct: 394 STSKKKKSKDKEKDRERKSESDK-DVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKT 452
Query: 439 ETRSRSRSNSKS 450
+ S + S
Sbjct: 453 KECSVEKGTGDS 464
Score = 92.8 bits (229), Expect = 6e-19
Identities = 67/216 (31%), Positives = 100/216 (46%), Gaps = 24/216 (11%)
Query: 290 SPSRHKSKSKSRSRSQERRVEEEKR---GSVSRGRSQEKSLRQSRSRSRSK--------G 338
SPS S +RV E + ++ + +EK R SRSRSRS+
Sbjct: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKR-RHSRSRSRSRRRRTPSSSR 265
Query: 339 GSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKED 398
RSRSRSR +S K + R+RS+ R RS SR + RSR RD KKKED
Sbjct: 266 HRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRD--------KKKED 317
Query: 399 TDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSK-PNLPSE 457
++ +S++P +S S R +S S+ RE R +GT + RS S+ P+
Sbjct: 318 KEKKRSKTPPKSYSTAR---RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRH 374
Query: 458 SRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
+ + K K RSR + ++ + S+ + + R
Sbjct: 375 KKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRER 410
Score = 89.4 bits (220), Expect = 7e-18
Identities = 78/286 (27%), Positives = 121/286 (42%), Gaps = 24/286 (8%)
Query: 211 SKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSK 270
S S + S+ + R R S + KKE+ R S+ +SRSR ++ S S+
Sbjct: 209 SLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRR---RTPSSSR 265
Query: 271 DQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQS 330
+ +SRS SR +S SKSRSR + + + S RGR + +
Sbjct: 266 HR--------------RSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTR 311
Query: 331 RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKS---ERSRKRGSKRDSK 387
+ K RS++ +S S R+ R SRE R RSRS ++S RS KR R
Sbjct: 312 DKKKEDKEKKRSKTPPKSYST-ARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPS 370
Query: 388 AGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETR--SRSR 445
KK+KK+D D+ +SR + +++ +K + RE + ES+ Q TR
Sbjct: 371 PRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDK-DVKQVTRDYDEEE 429
Query: 446 SNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSH 491
S+ E + + KT+ S + S S+ H
Sbjct: 430 QGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDH 475
Score = 76.6 bits (187), Expect = 5e-14
Identities = 64/195 (32%), Positives = 99/195 (50%), Gaps = 25/195 (12%)
Query: 180 RRRRSYSR-----SRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
RRRRS+SR SRS S++R + + K + RS + S+S +R RSRS SR R + RS
Sbjct: 291 RRRRSHSRERGRRSRSTSKTRDKKKED-KEKKRSKTPPKSYSTAR-RSRSASRERRRRRS 348
Query: 235 RSQSRSRSKKEKSRSPSKEKSRS---RSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
RS +RS +K RSP ++ SRS R H K + K K+++ ++ + RS
Sbjct: 349 RSGTRS---PKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDE----------RERST 395
Query: 292 SRHKSKSKSRSRSQERRVEEEKR-GSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS 350
S+ K KSK + + +ER+ E +K V+R +E+ S + + ++K
Sbjct: 396 SK-KKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKE 454
Query: 351 KDKRKGRKRSREESR 365
KG S ES+
Sbjct: 455 CSVEKGTGDSLRESK 469
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 2/146 (1%)
Query: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKS-RSRSRSGSRSRSKSRS 234
K S RRS S SR R RSRS + RS K S S S R + + + K RS
Sbjct: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERS 387
Query: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
R + R RS +K +S KEK R R + K + +E+ Q D+ + K
Sbjct: 388 RDE-RERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIE 446
Query: 295 KSKSKSRSRSQERRVEEEKRGSVSRG 320
K++ S E+ + R S G
Sbjct: 447 TGSPKTKECSVEKGTGDSLRESKVNG 472
Score = 50.8 bits (120), Expect = 3e-06
Identities = 41/111 (36%), Positives = 53/111 (47%), Gaps = 29/111 (26%)
Query: 413 KEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSES----RS-------R 461
++R H++S S R R S + +RSR RS+SKS+ S+S RS R
Sbjct: 244 EKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRR 303
Query: 462 SKSASKTRSRSKS------------------RSRSASRSPSRSRSRSHSRS 494
S+S SKTR + K RSRSASR R RSRS +RS
Sbjct: 304 SRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRS 354
Score = 38.1 bits (87), Expect = 0.018
Identities = 21/53 (39%), Positives = 31/53 (58%)
Query: 442 SRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
++S ++ +P+ E R S+S S++R R S RS SRSR RSHS+S
Sbjct: 229 AQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKS 281
Score = 35.8 bits (81), Expect = 0.092
Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 419 KSESSQREGRGESENAGTNQETRSRS-RSNSKSKPNLPSESRSRSKSASKTRSRSKSRSR 477
KS++S +E + Q S + + K + S SRSRS+ S RSR
Sbjct: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
Query: 478 SASRSPSRSRSRSHSRS 494
S SR S S+SRS RS
Sbjct: 271 SRSRRRSHSKSRSRRRS 287
Score = 30.0 bits (66), Expect = 5.0
Identities = 31/125 (24%), Positives = 53/125 (42%), Gaps = 10/125 (8%)
Query: 171 RLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRS 230
R + P RR + + + + + RSR R+ RS S K S K + R R +S S
Sbjct: 363 RKLSRSPSPRR---HKKEKKKDKDKERSRDERE-RSTS-KKKKSKDKEKDRER---KSES 414
Query: 231 KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS 290
+ +R ++E+ KEK + S K+K+ + EK D++ + K
Sbjct: 415 DKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGS-PKTKECSVEK-GTGDSLRESKVNG 472
Query: 291 PSRHK 295
H+
Sbjct: 473 DDHHE 477
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 107 bits (267), Expect = 2e-23
Identities = 96/341 (28%), Positives = 156/341 (45%), Gaps = 28/341 (8%)
Query: 163 TEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRS 222
TE GR + +++ G R + + + H +S S+H RK ++ + KSS ++S +S
Sbjct: 655 TEDTGRSLPSKKERSGKSHR--HKKKKKHKKS---SKHKRKHKADT-EEKSSKAESGEKS 708
Query: 223 RSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKI----- 277
+ + K R R +++S + + R P E S S + + R +++D ++ +
Sbjct: 709 K-----KRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEE 763
Query: 278 ----QNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR 333
+ ++ G S+ K K + S +RR KR S S RSQ S +
Sbjct: 764 GSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGT-KRSSRSSHRSQPSSGDED--- 819
Query: 334 SRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKK 393
S S R +S S+ + + SRSRSRS S R S+R + S
Sbjct: 820 --SDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDAS 877
Query: 394 KKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPN 453
+ R +S S S S + ++ S + +S+ A + ++ S+S +
Sbjct: 878 SDQSCYSRQRSYSDD-SYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYS 936
Query: 454 LPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
L S S+SRS+S S TR RS+SR RS S S SRSRS+ SRS
Sbjct: 937 L-SCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRS 976
Score = 96.3 bits (238), Expect = 6e-20
Identities = 86/290 (29%), Positives = 124/290 (42%), Gaps = 18/290 (6%)
Query: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSR---SGSRSRSKSR 233
P RRRR+ S+ S +K GSS H + + S + R+ ++
Sbjct: 743 PPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTK 802
Query: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
S+S RS+ S + S R H KS S+ ++ EE+ +++ + +SRS R
Sbjct: 803 RSSRSSHRSQPSSGDEDSDDASSHRLHQ--KSPSQYSEEEEEEDSGSEH-SRSRSRSGRR 859
Query: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRS---QEKSLRQSRSRSRSKGGSRSRSRSRSKS 350
H S SR + SR RS S RSR SK S + S
Sbjct: 860 HSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASS 919
Query: 351 KDKRKGRKRSREE-------SRSRSRSRSKS-ERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
K + K K S + S+SRSRSRS + ERSR RG R S S+ K++ + +
Sbjct: 920 KHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTA 979
Query: 403 QSRSPSRSVSKEREHAKSESSQREG-RGESENAGTNQETRSRSRSNSKSK 451
S SRS S++R + SQR G R S + +E S R +SK
Sbjct: 980 HSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSK 1029
Score = 91.3 bits (225), Expect = 2e-18
Identities = 117/387 (30%), Positives = 165/387 (42%), Gaps = 74/387 (19%)
Query: 126 QAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSY 185
+ G + + H GRK++G E S +RA GT+ + R + G
Sbjct: 771 EGGGGSSSQDHGGRKHKG--ELPPSSCQRRA-----GTKRSSRSSHRSQPSSGDEDSDDA 823
Query: 186 SRSRSHSRSRSR-----------SRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
S R H +S S+ S HSR SRSRSG SSH SR RS S S S +S
Sbjct: 824 SSHRLHQKSPSQYSEEEEEEDSGSEHSR-SRSRSGRRHSSHRSSR-RSYSSSSDASSDQS 881
Query: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
SR RS + S S + RSR HS S D A S+H
Sbjct: 882 -CYSRQRSYSDDSYSDYSD--RSRRHSKRSHDSDDSDYAS-----------------SKH 921
Query: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR 354
+SK S S +++ S S+ RS RSRS ++ SRSR RSRS S +
Sbjct: 922 RSKRHKYSSS-----DDDYSLSCSQSRS--------RSRSHTRERSRSRGRSRSSSCSRS 968
Query: 355 KGRKRSR-------EESRSRSRSRSKSER--SRKRGSKRDSKAGSSKKKK---KEDTDRS 402
+ ++RSR + SRS SR RS+S R S++ GS++ S S +++ + D RS
Sbjct: 969 RSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRS 1028
Query: 403 ---QSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESR 459
+S+SP S E + +GRG+ A S + S+ + E +
Sbjct: 1029 KIYRSQSPHYFRSGRGE---GPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDK 1085
Query: 460 SRSKSASKTRSRSKSRSRSASRSPSRS 486
+ S + K +SR R PS S
Sbjct: 1086 N---SVTAKLLLEKIQSRKVERKPSVS 1109
Score = 70.9 bits (172), Expect = 3e-12
Identities = 74/303 (24%), Positives = 109/303 (35%), Gaps = 47/303 (15%)
Query: 197 RSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSR 256
RS R SGS+ S +K GS + RS SKKE+S + K +
Sbjct: 624 RSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLP-----SKKERSGKSHRHKKK 678
Query: 257 SRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGS 316
+ + K + K K EEK ++ K K R + K S ER + E GS
Sbjct: 679 KKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGS 738
Query: 317 VSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSER 376
GS + R R +++D + R EE S
Sbjct: 739 ----------------------GSPAPPRRRRRAQDDSQRRSLPAEEGSS---------- 766
Query: 377 SRKRGSKRDSKAGSS------KKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE 430
G K + GSS +K K E S R S H SS E +
Sbjct: 767 ----GKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDD 822
Query: 431 SENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRS 490
+ + +Q++ S+ + + + SRSRS+S + S SR +S S + S
Sbjct: 823 ASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSC 882
Query: 491 HSR 493
+SR
Sbjct: 883 YSR 885
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 106 bits (264), Expect = 6e-23
Identities = 105/433 (24%), Positives = 181/433 (41%), Gaps = 36/433 (8%)
Query: 90 RSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEV-------TYADAHKGRKNE 142
R GRD+ + R + ++ R S ++++DY R E + DAH R E
Sbjct: 453 RDGRDRRDARDTRDRRELRDSRDMRDS-REMRDYSRDTKESRDPRDSRSTRDAHDYRDRE 511
Query: 143 GVIEFV---SYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRR-----RRSYSRSRSHSRS 194
G +Y + R+ + E + R E + SR R SR R
Sbjct: 512 GRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELP 571
Query: 195 RSRSRHSRKSRSRSGSSKSS-HSKSRSRSRSGSRSR-----SKSRSRSQSRSRSKKEKSR 248
SR SR S+ S SS S+ H +RS R R ++ ++R S R E+ R
Sbjct: 572 EKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDR 631
Query: 249 SPSKEKSRSRS---HSAGKSRSKSKDQAEEKIQ------NNDNVGKPKSRSPSRHKSKSK 299
++E+ + S G++ +D+ E+ + D + + R R + + +
Sbjct: 632 RDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERER 691
Query: 300 SRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKR 359
R R ++R E+E+ R R +E+ + R R R + R R R + +D+ K R+R
Sbjct: 692 ERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERER 751
Query: 360 SREE-SRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHA 418
REE R R R R + ER R+R +R + ++++++ D+ + R R ++RE
Sbjct: 752 EREERERERERERER-ERERERERERARERDKERERQRDWEDKDKGRDDRR---EKREEI 807
Query: 419 KSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRS 478
+ + + R+G E ++ + S S S + S S + + S+
Sbjct: 808 REDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQV 867
Query: 479 ASRSPSRSRSRSH 491
SRS S SH
Sbjct: 868 VRPQESRSLSPSH 880
Score = 102 bits (253), Expect = 1e-21
Identities = 102/454 (22%), Positives = 174/454 (38%), Gaps = 29/454 (6%)
Query: 44 DLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRS---GYGYR-RSGRDK---- 95
D RD D + +D+ R + +++R + RS + YR R GRD
Sbjct: 460 DARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKE 519
Query: 96 --YGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDM 153
Y +R+ R + SSR ++++ R + GR V E
Sbjct: 520 DTYPEESRSYGRNHLREESSRT---EIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSR 576
Query: 154 KRALEKLDGTEVNG--------RKIRLVEDKPGSRRRRSYSRSRSHSRSRS-RSRHSRKS 204
++D N R D+ R R +R S R R R +
Sbjct: 577 GSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRE 636
Query: 205 RSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGK 264
R + SS H R + R R R ++ + R +E+ R R +
Sbjct: 637 RDQRPSSPIRHQGRNDELERDERREERRVDRVDDR-RDERARERDRERERDRERERERER 695
Query: 265 SRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQE 324
R + +++ E +++ + + R R + + + R +ER E E+ R R +E
Sbjct: 696 ERDREREK-ERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE 754
Query: 325 KSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREE-SRSRSRSRSKSERSRKRGSK 383
+ R+ R R R + R R R R++ +DK + R+R E+ + R R K E R+ +
Sbjct: 755 ERERE-RERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNP 813
Query: 384 RDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSR 443
RD G ++K K+ S SP +S + REH+ + G ++E +
Sbjct: 814 RD---GHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRP 870
Query: 444 SRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSR 477
S S S +L + + R K + R +S R
Sbjct: 871 QESRSLSPSHLTEDRQGRWKEEDRKPERKESSRR 904
Score = 92.0 bits (227), Expect = 1e-18
Identities = 92/333 (27%), Positives = 132/333 (39%), Gaps = 29/333 (8%)
Query: 173 VEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKS 232
V+D+ + R R R R R + R +S S +G HS SR S S S+S
Sbjct: 286 VKDRIEEKTRDGKDRGRDFERQREK-RDKPRSTSPAGQH---HSPISSRHHSSS---SQS 338
Query: 233 RSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPS 292
S Q S S + K R+PS R+ + +S S + Q + P+ RSP
Sbjct: 339 GSSIQRHSPSPRRK-RTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQS--PPRHRSPM 395
Query: 293 RHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSR--SRSRSKS 350
R K + SQ E+R R +EK R+ R + + SR R
Sbjct: 396 REKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDG 455
Query: 351 KDKRKGR----KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSS-------KKKKKEDT 399
+D+R R +R +SR SR + SR RD + S + ++ DT
Sbjct: 456 RDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDT 515
Query: 400 DRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESR 459
R + P S S R H + ESS+ E R ES N ++ R + P LP E
Sbjct: 516 HRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELP-EKG 574
Query: 460 SRSKSASKTRSRSKSRS-----RSASRSPSRSR 487
SR S+ S S + + + S P R R
Sbjct: 575 SRGSRGSQIDSHSSNSNYHDSWETRSSYPERDR 607
Score = 87.0 bits (214), Expect = 3e-17
Identities = 90/327 (27%), Positives = 136/327 (41%), Gaps = 36/327 (11%)
Query: 199 RHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSR 258
R S KS R S KSS + + R S S + R+ ++SKK+ R+PS
Sbjct: 213 RKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPE 272
Query: 259 SHSAG---KSRSKSKDQAEEKIQNNDNVG-----------KPKSRSP---------SRHK 295
+ G K + K KD+ EEK ++ + G KP+S SP SRH
Sbjct: 273 DIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHH 332
Query: 296 SKSKSRSRSQERRVEEEKR---GSVSRGRSQEKSLRQSRSRSRSKGGS---RSRSRSRSK 349
S S S +R +R S S R+ LR+S S S S R +S R +
Sbjct: 333 SSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHR 392
Query: 350 SKDKRKGRKRSREESRSRSRSRSKSERSR-KRGSKRDSKAGSSKKKKKEDTDRSQSRSPS 408
S + KGR S+S R + E +R KR ++DS+ +++ ++D S+
Sbjct: 393 SPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSR---EEREYEQDQSSSRDHRDD 449
Query: 409 RSV--SKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSAS 466
R ++R A+ +RE R +S + ++E R SR +S+ S S +
Sbjct: 450 REPRDGRDRRDARDTRDRRELR-DSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYR 508
Query: 467 KTRSRSKSRSRSASRSPSRSRSRSHSR 493
R R SRS R+H R
Sbjct: 509 DREGRDTHRKEDTYPEESRSYGRNHLR 535
Score = 82.8 bits (203), Expect = 7e-16
Identities = 75/328 (22%), Positives = 128/328 (39%), Gaps = 18/328 (5%)
Query: 174 EDKPGSRRRRSYSRS-RSHSRSRSRSRHSRKSRS-RSGSSKSSHSKSRSRSRSGSRSRSK 231
ED G R R SR R + + +S SR R R R G + +R R +
Sbjct: 418 EDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMR 477
Query: 232 SRSRSQSRSRSKKEKSRSPSKEKSRSRSHS----AGKSRSKSKDQAEEKIQN--NDNVGK 285
+ SR KE SR P +S +H G+ + +D E+ ++ +++ +
Sbjct: 478 DSREMRDYSRDTKE-SRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLRE 536
Query: 286 PKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSR 345
SR+ R++S+++SRS + R+ SRGR E + SR S+ S S +
Sbjct: 537 ESSRTEIRNESRNESRSEIRNDRMGR------SRGRVPELPEKGSRGSRGSQIDSHSSNS 590
Query: 346 SRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSR 405
+ S + R +R +++ +R +RD + + ++ R Q R
Sbjct: 591 NYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGR 650
Query: 406 SPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSA 465
+ + RE + + R E A R R R + + R + +
Sbjct: 651 NDELERDERREERRVD---RVDDRRDERARERDRERERDRERERERERERDREREKEREL 707
Query: 466 SKTRSRSKSRSRSASRSPSRSRSRSHSR 493
+ R+R + R R R R R R H R
Sbjct: 708 ERERAREREREREKERDRERDRDRDHDR 735
Score = 79.7 bits (195), Expect = 6e-15
Identities = 76/279 (27%), Positives = 122/279 (43%), Gaps = 30/279 (10%)
Query: 179 SRRRRSYSRSRSHSRSRSRSRHSRKS-RSRSGSSKSSHSKSRSRS------RSGSRSRSK 231
++ R+ + RS S +RS S S R RS S+ S+H +S SGSR R K
Sbjct: 1178 AQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREK 1237
Query: 232 SRSRSQSRSRSKK-------EKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVG 284
++S + R + E SRS S ++ SRSHS+ +S +S Q + + D+
Sbjct: 1238 TKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRD 1297
Query: 285 KPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS 344
+ + R H R R +ERR ++ R +K ++R R R + R R
Sbjct: 1298 RLQERDRYEH-----DRERERERRDTRQREWD----RDADKDWPRNRDRDRLR--ERERE 1346
Query: 345 RSRSKSKDKRKGRKRSREESRSRSRSRSKS---ERSRKRGSKR-DSKAGSSKKKKKEDTD 400
R R K +D + R+R +S R R R + E S+ KR ++K ++ E T
Sbjct: 1347 RERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTS 1406
Query: 401 RSQSRSPSRSVSKEREHAKS-ESSQREGRGESENAGTNQ 438
R + K+ + E + + R ES AG ++
Sbjct: 1407 RDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDE 1445
Score = 79.3 bits (194), Expect = 7e-15
Identities = 69/246 (28%), Positives = 112/246 (45%), Gaps = 18/246 (7%)
Query: 238 SRSRSKKEKSRSPSKEKSRS-RSHSAGKSRSKSKDQAEEKIQNNDNVGKPK---SRSPSR 293
++ R ++ RS S +RS RSH++G+ RS S D A +D G+ + S S R
Sbjct: 1178 AQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRS--GDDQSGRKRVLHSGSRDR 1235
Query: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK 353
K+KS + ++ R+++ KRG SR S ++ +S S RS S + SRS S D
Sbjct: 1236 EKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDS 1295
Query: 354 RKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSK 413
R R + R R + +R R+R +RD++ + +D R++ R R +
Sbjct: 1296 R---------DRLQERDRYEHDRERER-ERRDTRQREWDRDADKDWPRNRDRDRLRERER 1345
Query: 414 EREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSK 473
ERE K RE E + + + R R R + + S R +K + +
Sbjct: 1346 ERERDKRRDLDRE--RERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLE 1403
Query: 474 SRSRSA 479
S SR +
Sbjct: 1404 STSRDS 1409
Score = 77.0 bits (188), Expect = 4e-14
Identities = 78/356 (21%), Positives = 136/356 (38%), Gaps = 53/356 (14%)
Query: 180 RRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSR 239
+R++S R RS R + R H R S+S R G R R K SR
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHD------RRHERREDTRGKRDREKD-----SR 431
Query: 240 SRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAE--EKIQNNDNVGKPKSRSPSRHKSK 297
+ E+ +S S++ R G+ R ++D + E + D + R SR +
Sbjct: 432 EEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKE 491
Query: 298 SKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSR---SRSRSRSKSKDKR 354
S+ S+ R + R R +++ SRS + R SR+ R++S+++
Sbjct: 492 SRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNES 551
Query: 355 KGRKRSREESRSRSRSRSKSERSRK--RGSKRDSKAGSS--------------KKKKKED 398
+ R+ RSR R E+ + RGS+ DS + +S + + E
Sbjct: 552 RSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPER 611
Query: 399 TDRSQSRSPS---------RSVSKEREHAKSESSQREGRGES------------ENAGTN 437
+R Q+R S R ++ER+ S + +GR + +
Sbjct: 612 DNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDR 671
Query: 438 QETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
++ R+R R + + R R + + + R R R+ R R + R R
Sbjct: 672 RDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRER 727
Score = 73.6 bits (179), Expect = 4e-13
Identities = 79/345 (22%), Positives = 133/345 (38%), Gaps = 47/345 (13%)
Query: 152 DMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSS 211
+ +R E+ E+ + R E + R R R R H R R R R + + R
Sbjct: 694 ERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERER 753
Query: 212 KS---SHSKSRSRSRSGSRSRSKSRSRSQSRSRSK----KEKSRSPSKEKSRSRSHSAGK 264
+ + R R R R R ++R R + R R + K+K R +EK R
Sbjct: 754 EERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREK-REEIREDRN 812
Query: 265 SRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS--------------KSRSRSQERRVE 310
R ++ +K N+ P+ +SP R + S K R SQ R +
Sbjct: 813 PRDGHDERKSKKRYRNEGSPSPR-QSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQ 871
Query: 311 EEKRGSVS------RGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREES 364
E + S S +GR +E+ + R S S+ + + S DK++ + E S
Sbjct: 872 ESRSLSPSHLTEDRQGRWKEEDRKPERKES-SRRYEEQELKEKVSSVDKQREQTEILESS 930
Query: 365 RSR---------SRSRSKSERSRKRGSKRDSKAGSSKKKKKED---TDRSQSRSPSR--- 409
R R S R S+R+ K+ KKKKED +R + S
Sbjct: 931 RMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQ 990
Query: 410 --SVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKP 452
S K ++ E +++ +G+S+ + +S+ + ++ P
Sbjct: 991 VFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPP 1035
Score = 67.8 bits (164), Expect = 2e-11
Identities = 81/328 (24%), Positives = 114/328 (34%), Gaps = 85/328 (25%)
Query: 181 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS---RSQ 237
R R R R R R+R R + R R K R R R R +
Sbjct: 762 RERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERK 821
Query: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP---KSRSPSR- 293
S+ R + E S SP + R R HS S D EK + V +P +S SPS
Sbjct: 822 SKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHL 881
Query: 294 ------------HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGG-- 339
K + K SR E + +EK SV + R Q + L SR R++ G
Sbjct: 882 TEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHH 941
Query: 340 --------SRSRSRSRSKSKDKRKGRKRSREESRSRSRS------------------RSK 373
R+ ++ K+K ++K K+ +E+ R + K
Sbjct: 942 QSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKK 1001
Query: 374 SERSRKRGSKRDSK------AGSSKKK-----------------------------KKED 398
S +++ SK DS A SKKK KKED
Sbjct: 1002 SIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKED 1061
Query: 399 T---DRSQSRSPSRSVSKEREHAKSESS 423
T D S P R+ E EH + ++
Sbjct: 1062 TAFSDWSDEDVPDRTEVTEAEHTATATT 1089
Score = 59.7 bits (143), Expect = 6e-09
Identities = 61/236 (25%), Positives = 101/236 (42%), Gaps = 29/236 (12%)
Query: 135 AHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNG-RKIRLVEDKPGSRRRRSYSR---SRS 190
AH+ ++ + V +S R EK E+ G RK R+ + K G R + S SRS
Sbjct: 1214 AHRSGDDQSGRKRVLHSG-SRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRS 1272
Query: 191 HSRSRSRSRHSRKSRSRSGSSKS----------SHSKSRSRSRSGSRSRS---------- 230
HS RS R+ SRSGS S H + R R R +R R
Sbjct: 1273 HSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWP 1332
Query: 231 KSRSRSQSRSRSK---KEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
++R R + R R + ++K R +E+ R S S + R + +D+ E Q ++V + +
Sbjct: 1333 RNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQ-IESVKRCE 1391
Query: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSR 343
++ H+ +S SR +E + + E++ + R+ S G S+
Sbjct: 1392 AKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDESK 1447
Score = 54.3 bits (129), Expect = 2e-07
Identities = 55/210 (26%), Positives = 86/210 (40%), Gaps = 28/210 (13%)
Query: 304 SQERRVEEEKRGSVSRGRSQEKSLRQSRS-RSRSKGGSRSRSR-SRSKSKDKRKGRKR-- 359
+Q R+ ++KR S SL +RS RS + G RS S S +S D + GRKR
Sbjct: 1178 AQHRKPMDQKRSS---------SLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVL 1228
Query: 360 ---SREESRSRSRSRSKSERSR----KRGS--------KRDSKAGSSKKKKKEDTDRSQS 404
SR+ +++S + +SR KRG ++DS++ SS++ E + S
Sbjct: 1229 HSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHS 1288
Query: 405 RSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKS 464
RS S + RE E + + R + +++ R R +
Sbjct: 1289 RSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERE 1348
Query: 465 ASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
K R + R R S S R R R R+
Sbjct: 1349 RDKRRDLDRERERLISDSVERDRDRDRDRT 1378
Score = 50.4 bits (119), Expect = 4e-06
Identities = 59/283 (20%), Positives = 112/283 (39%), Gaps = 20/283 (7%)
Query: 219 RSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQ 278
R + S + RS R R R K ++ ++ + R+ S+ R K+ + + +
Sbjct: 66 RGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVR---KESSRGRHR 122
Query: 279 NNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKG 338
+++ K R+P +S+ + E ++ G ++ E SL R + +
Sbjct: 123 EKEDIKITKERTP-----ESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQ--- 174
Query: 339 GSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKED 398
R + ++ +KR+ +E S RS+ S ++ SK + S K
Sbjct: 175 --RELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASK 232
Query: 399 TDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETR--SRSRSNSKSKPNLPS 456
DR S S + ++R ++S ++ R S ++ + + K K +
Sbjct: 233 KDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEE 292
Query: 457 ESR---SRSKSASKTR-SRSKSRSRS-ASRSPSRSRSRSHSRS 494
++R R + + R R K RS S A + S SR HS S
Sbjct: 293 KTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSS 335
Score = 40.4 bits (93), Expect = 0.004
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 9/146 (6%)
Query: 350 SKDKRKGRKRSREESRSRSRSRSKSERSRK-RGSKRDSKAGSSKKKKKEDTDRSQSRSPS 408
++D + R+R E + + RK KR S GS++ + + R RSPS
Sbjct: 1153 NEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGR--LRSPS 1210
Query: 409 RSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKT 468
+ A + GR ++G+ +++S + + + + + S S +
Sbjct: 1211 ------NDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTS 1264
Query: 469 RSRSKSRSRSASRSPSRSRSRSHSRS 494
R SRS S+ RS S + HSRS
Sbjct: 1265 SDRQDSRSHSSRRSSPESDRQVHSRS 1290
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 105 bits (263), Expect = 7e-23
Identities = 122/363 (33%), Positives = 168/363 (46%), Gaps = 58/363 (15%)
Query: 145 IEFVSYSDMKRAL-----EKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSR 199
IE ++ +D+ R L E+L L D R S S R+ S
Sbjct: 1725 IEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSS 1784
Query: 200 HSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRS 259
+ K +H KS+ + K R S RSRSK+ KS S+ KSR R+
Sbjct: 1785 EEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRD-SSLRSRSKRSKS---SEHKSRKRT 1840
Query: 260 HSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSR 319
+SRS+++ ++ KS+S H+S+++SRSRS+ RR R S SR
Sbjct: 1841 ---SESRSRARKRSS------------KSKS---HRSQTRSRSRSRRRRRSSRSR-SKSR 1881
Query: 320 GR---SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKG-RKRSREES-RSRSRSRSKS 374
GR S+EK R + RS+ SR R R RS S+D RK R RSR S RSRS + S+
Sbjct: 1882 GRRSVSKEKRKRSPKHRSK----SRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRR 1937
Query: 375 ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENA 434
RSR G +R S++ + T +SR+PSR +S + R R S +
Sbjct: 1938 RRSRSVGRRRSFSISPSRRSR---TPSRRSRTPSR---------RSRTPSRRSRTPSRRS 1985
Query: 435 GTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRS---RSASRSP-SRSRSRS 490
T RSR+ S+ + + S R RS S S R R +SR+ R SRSP R RSRS
Sbjct: 1986 RTPSR---RSRTPSRRRRS-RSVVRRRSFSISPVRLR-RSRTPLRRRFSRSPIRRKRSRS 2040
Query: 491 HSR 493
R
Sbjct: 2041 SER 2043
Score = 103 bits (258), Expect = 3e-22
Identities = 88/279 (31%), Positives = 128/279 (45%), Gaps = 28/279 (10%)
Query: 187 RSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSR-SRSKKE 245
++++ + + RSRS SKSS KSR R+ S+SRSR++ R S+SK
Sbjct: 1805 KNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRT-------SESRSRARKRSSKSKSH 1857
Query: 246 KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQ 305
+S++ S+ +SR R S SRS+SK + + PK RS SR + + +S SR
Sbjct: 1858 RSQTRSRSRSRRRRRS---SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDN 1914
Query: 306 ERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESR 365
+ V R R RS S R+ RSRS G R RS S S S+ R +RSR SR
Sbjct: 1915 RKTVRARSRTPSRRSRSHTPSRRR---RSRSVG--RRRSFSISPSRRSRTPSRRSRTPSR 1969
Query: 366 SRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQR 425
RSR+ S+ R+ R S+ S+ + +++ SRSV + R + S R
Sbjct: 1970 -RSRTPSRRSRTPSRRSRTPSRRSRTPSRRRR----------SRSVVRRRSFSISPVRLR 2018
Query: 426 EGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKS 464
R + R R RS S + P K+
Sbjct: 2019 RSRTPLRRRFSRSPIR-RKRSRSSERGRSPKRLTDLDKA 2056
Score = 97.4 bits (241), Expect = 3e-20
Identities = 96/288 (33%), Positives = 136/288 (47%), Gaps = 38/288 (13%)
Query: 130 VTYADAH-KGRKNE----GVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRS 184
V D H K +KN+ G E S ++ ++ +E RK R E + +R+R S
Sbjct: 1794 VKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRK-RTSESRSRARKRSS 1852
Query: 185 YSRS-RSHSRSRSRSRHSR---KSRSRSGSSKSSHSKSRSRS---RSGSRSRSKSRSRSQ 237
S+S RS +RSRSRSR R +SRS+S +S + R RS RS SR R + RS S+
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSR 1912
Query: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK--SRSPSRHK 295
++ + +SR+PS+ RSRSH+ + R + +VG+ + S SPSR
Sbjct: 1913 DNRKTVRARSRTPSR---RSRSHTPSRRR------------RSRSVGRRRSFSISPSRRS 1957
Query: 296 SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRK 355
RSR+ RR R S + R R+SR+ SR + RSRS R +S
Sbjct: 1958 RTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRR---RSRSVVRRRSFSISP 2014
Query: 356 GRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQ 403
R R R SRS R R R S+R K+ D D++Q
Sbjct: 2015 VRLRRSRTPLRRRFSRSPIRRKRSRSSER-----GRSPKRLTDLDKAQ 2057
Score = 76.3 bits (186), Expect = 6e-14
Identities = 55/147 (37%), Positives = 79/147 (53%), Gaps = 17/147 (11%)
Query: 349 KSKDKRKGRKRSREESRSRSRS-RSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
K+K++ KG K + +S RSRS RSKS + R +S++ + K+ K + RSQ+RS
Sbjct: 1805 KNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSR 1864
Query: 408 SRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASK 467
SRS R +S S+ + RG RS S+ K P S+SR R + S
Sbjct: 1865 SRS----RRRRRSSRSRSKSRGR----------RSVSKEKRKRSPKHRSKSRERKRKRSS 1910
Query: 468 TRSRSKSRSRSASRSPSRSRSRSHSRS 494
+R K+ R+ SR+PSR RSRSH+ S
Sbjct: 1911 SRDNRKT-VRARSRTPSR-RSRSHTPS 1935
Score = 37.7 bits (86), Expect = 0.024
Identities = 35/120 (29%), Positives = 57/120 (47%), Gaps = 13/120 (10%)
Query: 387 KAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE-----SENAGTNQETR 441
+AG D R +S + S VS E A SS+ + E + +++ +
Sbjct: 1749 RAGIEGPLLASDVGRDRSAA-SPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNK 1807
Query: 442 SRSRSNSKSKPNLPSESRSRSKSASKTRSR---SKSRSRSASRSPS----RSRSRSHSRS 494
+R + + K + SRS+ +S+ +SR S+SRSR+ RS RS++RS SRS
Sbjct: 1808 NRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRS 1867
Score = 35.8 bits (81), Expect = 0.092
Identities = 18/60 (30%), Positives = 29/60 (48%)
Query: 358 KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREH 417
K +SR S ++ + SK+ K + KKKKK++ ++ R P S SK + H
Sbjct: 84 KEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSH 143
Score = 31.2 bits (69), Expect = 2.3
Identities = 32/141 (22%), Positives = 52/141 (36%), Gaps = 13/141 (9%)
Query: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
SK R Q S + E + + + + S EE +Q + V
Sbjct: 15 SKFREIQQELSSGRNEGQLNGETNTPIEGNQAGDAAASARSLPNEEIVQKIEEVLSGVLD 74
Query: 290 SPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSK 349
+ R+K K SR SR S + +SK + +++ + K
Sbjct: 75 TELRYKPDLKEGSRK-------------SRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKK 121
Query: 350 SKDKRKGRKRSREESRSRSRS 370
K+K K KR EES S+++S
Sbjct: 122 KKEKEKKYKRQPEESESKTKS 142
Score = 30.4 bits (67), Expect = 3.9
Identities = 11/44 (25%), Positives = 25/44 (56%)
Query: 281 DNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQE 324
D + KS+ +HK+K K + + +E++ + + S S+ +S +
Sbjct: 101 DEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHD 144
Score = 30.0 bits (66), Expect = 5.0
Identities = 15/63 (23%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 201 SRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSH 260
SRKSR S + + +S+ + ++K + + + + + K R P + +S+++SH
Sbjct: 87 SRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYK---RQPEESESKTKSH 143
Query: 261 SAG 263
G
Sbjct: 144 DDG 146
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 105 bits (263), Expect = 7e-23
Identities = 122/363 (33%), Positives = 168/363 (46%), Gaps = 58/363 (15%)
Query: 145 IEFVSYSDMKRAL-----EKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSR 199
IE ++ +D+ R L E+L L D R S S R+ S
Sbjct: 1725 IEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSS 1784
Query: 200 HSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRS 259
+ K +H KS+ + K R S RSRSK+ KS S+ KSR R+
Sbjct: 1785 EEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRD-SSLRSRSKRSKS---SEHKSRKRT 1840
Query: 260 HSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSR 319
+SRS+++ ++ KS+S H+S+++SRSRS+ RR R S SR
Sbjct: 1841 ---SESRSRARKRSS------------KSKS---HRSQTRSRSRSRRRRRSSRSR-SKSR 1881
Query: 320 GR---SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKG-RKRSREES-RSRSRSRSKS 374
GR S+EK R + RS+ SR R R RS S+D RK R RSR S RSRS + S+
Sbjct: 1882 GRRSVSKEKRKRSPKHRSK----SRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRR 1937
Query: 375 ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENA 434
RSR G +R S++ + T +SR+PSR +S + R R S +
Sbjct: 1938 RRSRSVGRRRSFSISPSRRSR---TPSRRSRTPSR---------RSRTPSRRSRTPSRRS 1985
Query: 435 GTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRS---RSASRSP-SRSRSRS 490
T RSR+ S+ + + S R RS S S R R +SR+ R SRSP R RSRS
Sbjct: 1986 RTPSR---RSRTPSRRRRS-RSVVRRRSFSISPVRLR-RSRTPLRRRFSRSPIRRKRSRS 2040
Query: 491 HSR 493
R
Sbjct: 2041 SER 2043
Score = 103 bits (258), Expect = 3e-22
Identities = 88/279 (31%), Positives = 128/279 (45%), Gaps = 28/279 (10%)
Query: 187 RSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSR-SRSKKE 245
++++ + + RSRS SKSS KSR R+ S+SRSR++ R S+SK
Sbjct: 1805 KNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRT-------SESRSRARKRSSKSKSH 1857
Query: 246 KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQ 305
+S++ S+ +SR R S SRS+SK + + PK RS SR + + +S SR
Sbjct: 1858 RSQTRSRSRSRRRRRS---SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDN 1914
Query: 306 ERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESR 365
+ V R R RS S R+ RSRS G R RS S S S+ R +RSR SR
Sbjct: 1915 RKTVRARSRTPSRRSRSHTPSRRR---RSRSVG--RRRSFSISPSRRSRTPSRRSRTPSR 1969
Query: 366 SRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQR 425
RSR+ S+ R+ R S+ S+ + +++ SRSV + R + S R
Sbjct: 1970 -RSRTPSRRSRTPSRRSRTPSRRSRTPSRRRR----------SRSVVRRRSFSISPVRLR 2018
Query: 426 EGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKS 464
R + R R RS S + P K+
Sbjct: 2019 RSRTPLRRRFSRSPIR-RKRSRSSERGRSPKRLTDLDKA 2056
Score = 97.4 bits (241), Expect = 3e-20
Identities = 96/288 (33%), Positives = 136/288 (47%), Gaps = 38/288 (13%)
Query: 130 VTYADAH-KGRKNE----GVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRS 184
V D H K +KN+ G E S ++ ++ +E RK R E + +R+R S
Sbjct: 1794 VKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRK-RTSESRSRARKRSS 1852
Query: 185 YSRS-RSHSRSRSRSRHSR---KSRSRSGSSKSSHSKSRSRS---RSGSRSRSKSRSRSQ 237
S+S RS +RSRSRSR R +SRS+S +S + R RS RS SR R + RS S+
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSR 1912
Query: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK--SRSPSRHK 295
++ + +SR+PS+ RSRSH+ + R + +VG+ + S SPSR
Sbjct: 1913 DNRKTVRARSRTPSR---RSRSHTPSRRR------------RSRSVGRRRSFSISPSRRS 1957
Query: 296 SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRK 355
RSR+ RR R S + R R+SR+ SR + RSRS R +S
Sbjct: 1958 RTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRR---RSRSVVRRRSFSISP 2014
Query: 356 GRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQ 403
R R R SRS R R R S+R K+ D D++Q
Sbjct: 2015 VRLRRSRTPLRRRFSRSPIRRKRSRSSER-----GRSPKRLTDLDKAQ 2057
Score = 76.3 bits (186), Expect = 6e-14
Identities = 55/147 (37%), Positives = 79/147 (53%), Gaps = 17/147 (11%)
Query: 349 KSKDKRKGRKRSREESRSRSRS-RSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
K+K++ KG K + +S RSRS RSKS + R +S++ + K+ K + RSQ+RS
Sbjct: 1805 KNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSR 1864
Query: 408 SRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASK 467
SRS R +S S+ + RG RS S+ K P S+SR R + S
Sbjct: 1865 SRS----RRRRRSSRSRSKSRGR----------RSVSKEKRKRSPKHRSKSRERKRKRSS 1910
Query: 468 TRSRSKSRSRSASRSPSRSRSRSHSRS 494
+R K+ R+ SR+PSR RSRSH+ S
Sbjct: 1911 SRDNRKT-VRARSRTPSR-RSRSHTPS 1935
Score = 37.7 bits (86), Expect = 0.024
Identities = 35/120 (29%), Positives = 57/120 (47%), Gaps = 13/120 (10%)
Query: 387 KAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE-----SENAGTNQETR 441
+AG D R +S + S VS E A SS+ + E + +++ +
Sbjct: 1749 RAGIEGPLLASDVGRDRSAA-SPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNK 1807
Query: 442 SRSRSNSKSKPNLPSESRSRSKSASKTRSR---SKSRSRSASRSPS----RSRSRSHSRS 494
+R + + K + SRS+ +S+ +SR S+SRSR+ RS RS++RS SRS
Sbjct: 1808 NRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRS 1867
Score = 35.8 bits (81), Expect = 0.092
Identities = 18/60 (30%), Positives = 29/60 (48%)
Query: 358 KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREH 417
K +SR S ++ + SK+ K + KKKKK++ ++ R P S SK + H
Sbjct: 84 KEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSH 143
Score = 31.2 bits (69), Expect = 2.3
Identities = 32/141 (22%), Positives = 52/141 (36%), Gaps = 13/141 (9%)
Query: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
SK R Q S + E + + + + S EE +Q + V
Sbjct: 15 SKFREIQQELSSGRNEGQLNGETNTPIEGNQAGDAAASARSLPNEEIVQKIEEVLSGVLD 74
Query: 290 SPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSK 349
+ R+K K SR SR S + +SK + +++ + K
Sbjct: 75 TELRYKPDLKEGSRK-------------SRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKK 121
Query: 350 SKDKRKGRKRSREESRSRSRS 370
K+K K KR EES S+++S
Sbjct: 122 KKEKEKKYKRQPEESESKTKS 142
Score = 30.4 bits (67), Expect = 3.9
Identities = 11/44 (25%), Positives = 25/44 (56%)
Query: 281 DNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQE 324
D + KS+ +HK+K K + + +E++ + + S S+ +S +
Sbjct: 101 DEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHD 144
Score = 30.0 bits (66), Expect = 5.0
Identities = 15/63 (23%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 201 SRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSH 260
SRKSR S + + +S+ + ++K + + + + + K R P + +S+++SH
Sbjct: 87 SRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYK---RQPEESESKTKSH 143
Query: 261 SAG 263
G
Sbjct: 144 DDG 146
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 105 bits (263), Expect = 7e-23
Identities = 109/311 (35%), Positives = 138/311 (44%), Gaps = 54/311 (17%)
Query: 106 LIVENLSSRCSWQDLKDYMRQAGEV--TYADAHKGRKNEGVIEFVSYSDMKRALEK---L 160
L V+NL+ R S L+ + G V Y K FV + D + A + +
Sbjct: 16 LKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRDAQDAEAAM 75
Query: 161 DGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRS 220
DG E++GR++R+ + G RR RSR + + RSR G
Sbjct: 76 DGAELDGRELRVQVARYG---RRDLPRSR---------QGEPRGRSRGGGY--------- 114
Query: 221 RSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNN 280
G RSRS R RS+S R + +SR PS +SRSRS G S+S
Sbjct: 115 ----GRRSRSYGR-RSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRS----------- 158
Query: 281 DNVGKPKSRSP---SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSK 337
P SRSP SR+ SRSR +E R S G S + R SRS SK
Sbjct: 159 -----PYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSS--SGYSNSRYSRYHSSRSHSK 211
Query: 338 GGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKS-ERSRKRGSKRDSKAGS-SKKKK 395
GS + SRS S SK R +S SRSRSRSRS S RS R SKR SK+ S SK+
Sbjct: 212 SGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRPP 271
Query: 396 KEDTDRSQSRS 406
K + Q S
Sbjct: 272 KSPEEEGQMSS 282
Score = 94.7 bits (234), Expect = 2e-19
Identities = 88/283 (31%), Positives = 124/283 (43%), Gaps = 40/283 (14%)
Query: 6 IGRLSYQARERDVERFFKGYGKILEVDLKN--------GYGFVEFDDLRDADDAVYELNG 57
+ L+Y+ + R F+ YG++ +V + G+ FV F D RDA DA ++G
Sbjct: 18 VDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRDAQDAEAAMDG 77
Query: 58 KDLCGERVIVEHARGPRRD------GSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENL 111
+L G + V+ AR RRD G G GY R R YG +R+ R
Sbjct: 78 AELDGRELRVQVARYGRRDLPRSRQGEPRGRSRGGGYGRRSR-SYGRRSRSPRR------ 130
Query: 112 SSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIR 171
+ R G + R YS + + + + + R
Sbjct: 131 ---------RHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYR 181
Query: 172 LVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSK 231
SR S+ S +S SR HS +S S+SGSS SS S S S+S S RS+S
Sbjct: 182 ------ESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSS 235
Query: 232 SRSRSQSRSRSKKEKSRSP---SKEKSRSRSHSAGKSRSKSKD 271
S SRS+SRSRS +RSP SK KS+SRS S +S ++
Sbjct: 236 SVSRSRSRSRS-SSMTRSPPRVSKRKSKSRSRSKRPPKSPEEE 277
Score = 87.4 bits (215), Expect = 3e-17
Identities = 72/190 (37%), Positives = 90/190 (47%), Gaps = 13/190 (6%)
Query: 312 EKRGSVSR-GRSQEKSLRQSRSRSRSKGGS---RSRSRSRSKSKDKRKGRKRSREESRSR 367
E R V+R GR RQ R RS+GG RSRS R +R+ R RSR S SR
Sbjct: 84 ELRVQVARYGRRDLPRSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCSR 143
Query: 368 SRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREG 427
SRSRS+ SR S S + + RS+ R S S S
Sbjct: 144 SRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRY 203
Query: 428 RGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSP---S 484
++ + T SRS S SK S S RSKS+S +RSRS+SRS S +RSP S
Sbjct: 204 HSSRSHSKSGSSTSSRSASTSK------SSSARRSKSSSVSRSRSRSRSSSMTRSPPRVS 257
Query: 485 RSRSRSHSRS 494
+ +S+S SRS
Sbjct: 258 KRKSKSRSRS 267
Score = 84.3 bits (207), Expect = 2e-16
Identities = 77/251 (30%), Positives = 112/251 (44%), Gaps = 24/251 (9%)
Query: 248 RSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQER 307
R P + R + R ++D AE + + G+ +R+ + RSR E
Sbjct: 47 REPHTKAPRGFAFVRFHDRRDAQD-AEAAMDGAELDGRELRVQVARYGRRDLPRSRQGEP 105
Query: 308 RVEEEKRGSVSRGRSQEKSLR--QSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESR 365
R G R RS + R + R RSRS+G S SRSRSRS+ + R R
Sbjct: 106 RGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPY 165
Query: 366 SRSR------SRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK 419
SRSR SRS+ SR GS S S+ + + + RS S+S S + S+ +K
Sbjct: 166 SRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSK 225
Query: 420 SESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSA 479
S S++R + ++ +RSRSRS S S P SK +S+S+SRS+
Sbjct: 226 SSSARR--------SKSSSVSRSRSRSRSSSMTRSPPR-------VSKRKSKSRSRSKRP 270
Query: 480 SRSPSRSRSRS 490
+SP S
Sbjct: 271 PKSPEEEGQMS 281
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 103 bits (257), Expect = 4e-22
Identities = 115/471 (24%), Positives = 183/471 (38%), Gaps = 66/471 (14%)
Query: 87 GYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIE 146
G + S DK P + + +LS R Y ++ HK R+ E ++
Sbjct: 380 GEKWSKGDKLSDPCSSRWD--ERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVK 437
Query: 147 FVSYSDMKRALEK--------------LDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHS 192
++ + ++ ++ + R+++ D+ S R S S S
Sbjct: 438 HKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSK 497
Query: 193 RSRSRS--------RHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKK 244
R S+S HS + RS S S+S+ SRSR+ S+S S SRSRS+SRS SK
Sbjct: 498 RDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKS 557
Query: 245 EKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP------------KSRSPS 292
+ SK ++ S + K++ QN + V +P S PS
Sbjct: 558 GHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPS 617
Query: 293 RHKSKSKSRSRSQERRVEEEKR-------------------GSVSRGRSQEKSLRQSRSR 333
R K K S ER E + + GS S +EK+ +S
Sbjct: 618 RWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQST 677
Query: 334 ------SRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRD-- 385
S+ RSRSRS S+S+ + RSR + S SRSRS S RS R D
Sbjct: 678 YSKYSDRSSESSPRSRSRS-SRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHS 736
Query: 386 --SKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSR 443
S++ S +D R++ R S H K SS + G ++ + R
Sbjct: 737 QCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVR 796
Query: 444 SRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
S S+S + S+S S A+++ + + + + ++R +S
Sbjct: 797 KYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKS 847
Score = 100 bits (248), Expect = 4e-21
Identities = 98/342 (28%), Positives = 148/342 (43%), Gaps = 36/342 (10%)
Query: 171 RLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKS------------SHSKS 218
R E P SR R S SRS S S +RSRS S SRSRS SS+S S S S
Sbjct: 684 RSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSS 743
Query: 219 RSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQ 278
+ S R+K R RS + S K S S EK+ + G+ RS + E
Sbjct: 744 YTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSE--- 800
Query: 279 NNDNVGKPKSRSPSRHKSKSKSRS-RSQERRVEEEKRGSVSRGRS-QEKSLRQSRSRS-R 335
SRS + S S+ S ++ + E+EK+G + R + QEK+ + +S+S R
Sbjct: 801 ---------SRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSER 851
Query: 336 SKGGSRSRSRSRSKSKDKRKGRKRSREE-SRSRSRSRSKSERSRKRGSKRDSKAGSSKKK 394
S+ R+ + S R G K R+ + S+ S S SER + SK DS S K++
Sbjct: 852 ECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEE 911
Query: 395 KKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRG--ESENAGTNQETRSRSRSNSKSKP 452
+ +D S K + + +S + G +S T+ S SNS++
Sbjct: 912 GEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNR 971
Query: 453 NLPSESRSRSKS------ASKTRSRSKSRSRSASRSPSRSRS 488
P + + SK K + + K + ++P R ++
Sbjct: 972 GKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQA 1013
Score = 99.4 bits (246), Expect = 7e-21
Identities = 90/326 (27%), Positives = 156/326 (47%), Gaps = 29/326 (8%)
Query: 184 SYSRSRSHSRS--RSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSR 241
SY + +S S + S++S +S S S+S S+SRS SRS +RSRS + S S+SRS
Sbjct: 663 SYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSP 722
Query: 242 SKKEKSRSPSKEKSR-SRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS-- 298
S + SR+ + S+ SRS S S +A+ +++++ GK S S +H S S
Sbjct: 723 SSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSS---GKKNSVSHKKHSSSSEK 779
Query: 299 -------KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351
K R RS R E R S+ E+S Q+ ++ K R+ +K +
Sbjct: 780 TLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNK-Q 838
Query: 352 DKRKGRKRSREE-----SRSRSRSRSKSERSRKRGS-KRDSKAGSSKKKKKEDTDRSQSR 405
+K +G ++S+ E S+ R+ + S+ R KR + AGS K D++ + R
Sbjct: 839 EKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGS-----KWDSESNSER 893
Query: 406 SPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSA 465
+++ SK H S+ + E +SE+ + + + + S + +LP ++ + S
Sbjct: 894 DVTKN-SKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSK 952
Query: 466 SKTRSRSKSRSRSASRSPSRSRSRSH 491
+T S S S ++ +R + + H
Sbjct: 953 QRT-STSDSEGSCSNSENNRGKPQKH 977
Score = 89.4 bits (220), Expect = 7e-18
Identities = 99/364 (27%), Positives = 143/364 (39%), Gaps = 44/364 (12%)
Query: 171 RLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRS 230
RL +P S + S S S S RSRS S +S + SG +
Sbjct: 371 RLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKR 430
Query: 231 KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS 290
+ + + + + KK+K K+ + R S SK + D +S S
Sbjct: 431 RKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIES-SKSSTRRMKSSCDRERSSRSSS 489
Query: 291 PSRHKSKSKSRSRS----QERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346
S H S + S+S Q + S+ SQ S SRSR+ SK S SRSRS
Sbjct: 490 LSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRS 549
Query: 347 RSKSKDKRKGRKRSREESRSRSRSRS-----KSERSRKRGSKRD---------------- 385
+S+S K RKR+ + R + S K+E R ++ +
Sbjct: 550 KSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIP 609
Query: 386 -------SKAGSSKKKKKEDTDRSQSRSPSRS------VSKEREHAKSESSQREGRGESE 432
S+ +K K +R Q + + + K S +
Sbjct: 610 LSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREK 669
Query: 433 NAGTNQETRSR--SRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRS 490
N+ ++Q T S+ RS+ S + SRSRS S S TRSRS + S S SRSPS SRS
Sbjct: 670 NSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPS---SRS 726
Query: 491 HSRS 494
HSR+
Sbjct: 727 HSRN 730
Score = 85.5 bits (210), Expect = 1e-16
Identities = 102/384 (26%), Positives = 151/384 (39%), Gaps = 81/384 (21%)
Query: 182 RRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSR 241
R SY RS+SHS+S SR SRSR+ S SSHS+SRS+SRS S+S + R+ R
Sbjct: 516 RDSY-RSKSHSQSYSRG----SSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKT 570
Query: 242 SKKEKSRSPSKEK---------------------------SRSRSHSAGKSRSKSKDQAE 274
+ + P K + S S S K K +
Sbjct: 571 ASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSY 630
Query: 275 EKIQNND----------------NVGKPKSRSPSRHKSKSKSRS------RSQERRVEEE 312
E+IQ N+ K S S HK + S S + +R E
Sbjct: 631 ERIQEMKAKTTHLLPIQSTYSLANI-KETGSSSSYHKREKNSESDQSTYSKYSDRSSESS 689
Query: 313 KRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS-RSRSKSKDKRKGRKRSREESRSRSRSR 371
R RS+ S +RSRS + SRSRS SRS S++K + S S S
Sbjct: 690 PRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISS 749
Query: 372 SKSERSRKRGSKRDSKAGSSKKKKKEDTDR-------------------SQSRSPSRSVS 412
R+++R K S KK +++ S+SRS S S
Sbjct: 750 DDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRS-SLDYS 808
Query: 413 KEREHAKSESSQ----REGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKT 468
+ E + +++Q +E +G+ E QE ++R SKS+ P + K
Sbjct: 809 SDSEQSSVQATQSAQEKEKQGQMERTHNKQE-KNRGEEKSKSERECPHSKKRTLKENLSD 867
Query: 469 RSRSKSRSRSASRSPSRSRSRSHS 492
R+ S+ + + + S+ S S+S
Sbjct: 868 HLRNGSKPKRKNYAGSKWDSESNS 891
Score = 83.6 bits (205), Expect = 4e-16
Identities = 72/183 (39%), Positives = 91/183 (49%), Gaps = 23/183 (12%)
Query: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGS-RSRSKS 232
+++ SR S SRS S SRS+S + KSR R+ S SHS+SRSRS + S RSRS S
Sbjct: 1299 DEQTPSRDDDSQSRSPSRSRSKSET----KSRHRTRSVSYSHSRSRSRSSTSSYRSRSYS 1354
Query: 233 RSRSQSRSRSKKEKSRSPSKEKSRS-RSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
RSRS+ + +SRS S +S R+ S +SRS S D P SRS
Sbjct: 1355 RSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYD--------------PHSRSR 1400
Query: 292 SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351
S SRSRS+ R ++ S RGRS + R RS RS S RS S+
Sbjct: 1401 SYTYDSYYSRSRSRSR---SQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSE 1457
Query: 352 DKR 354
R
Sbjct: 1458 SSR 1460
Score = 83.2 bits (204), Expect = 5e-16
Identities = 72/208 (34%), Positives = 98/208 (47%), Gaps = 25/208 (12%)
Query: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR 235
+PGS +R + R R++ S + S S SRSRS+S ++SR ++RS
Sbjct: 1273 RPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSV 1332
Query: 236 SQSRSRSKKEKSRSPSKEKSRSRSHSAG-KSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
S S SRS+ S S + +S SRS S G SR +++ ++ RS H
Sbjct: 1333 SYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSS------------SYRSYKSH 1380
Query: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR 354
++ S+SRSRS SR RS SRSRSRS+ RS S R +S ++R
Sbjct: 1381 RTSSRSRSRSSSYDPH-------SRSRSYTYDSYYSRSRSRSR-SQRSDSYHRGRSYNRR 1432
Query: 355 KGRKRS----REESRSRSRSRSKSERSR 378
RS E RS S RS SE SR
Sbjct: 1433 SRSCRSYGSDSESDRSYSHHRSPSESSR 1460
Score = 82.0 bits (201), Expect = 1e-15
Identities = 99/381 (25%), Positives = 145/381 (38%), Gaps = 68/381 (17%)
Query: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKS------------------------ 213
GS R R+ S+S SHSRSRS+SR S KS R +SKS
Sbjct: 531 GSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMA 590
Query: 214 --------------------SHSKSRSRSRSGSRSRSKSRSRSQSRSRS-------KKEK 246
S S SR + G + S R Q +
Sbjct: 591 QNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTY 650
Query: 247 SRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQE 306
S + KE S S+ + S+S K + + P+SRS S +S+S SRS ++
Sbjct: 651 SLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSS-RSRSYSRSYTRS 709
Query: 307 RRV---EEEKRGSVSRGRSQEKSLRQSR-SRSRSKGGSRSRSRSRSKSKDKRKGRKRSRE 362
R + R SR S+ K S+ SRS S S R+K + + G+K S
Sbjct: 710 RSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVS 769
Query: 363 ESRSRSRSRSKSERSRKRGSKRDS---KAGSSKKKKKEDTDRSQSRSPSRSVSKEREH-- 417
+ S S +G R S K S+ +D QS + ++E+E
Sbjct: 770 HKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQG 829
Query: 418 --AKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSK-- 473
++ + Q + RGE ++ + S+ R+ K NL R+ SK K + SK
Sbjct: 830 QMERTHNKQEKNRGEEKSKSERECPHSKKRT---LKENLSDHLRNGSKPKRKNYAGSKWD 886
Query: 474 SRSRSASRSPSRSRSRSHSRS 494
S S S S++ SH S
Sbjct: 887 SESNSERDVTKNSKNDSHPSS 907
Score = 79.0 bits (193), Expect = 9e-15
Identities = 89/375 (23%), Positives = 146/375 (38%), Gaps = 52/375 (13%)
Query: 161 DGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRS 220
+G++ + E S SR R H R R + + S+K R + SS+ +K +
Sbjct: 196 EGSDSSSNSSSSSESSSESELEHERSRRRKHKR-RPKVKRSKKRRKEASSSEEPRNK-HA 253
Query: 221 RSRSGSRSRSKSRSRSQSRSRSKKEK---------------------------------- 246
+ G RS + + S +K+EK
Sbjct: 254 MNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIP 313
Query: 247 -------SRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSK 299
+ PS KS + G R + ++ +++D+ S +P K + +
Sbjct: 314 DVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDD---DSSETPPHWKEEMQ 370
Query: 300 S----RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRK 355
R S E+ + +K R E+SL Q RSRS S G S + S +K
Sbjct: 371 RLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQ-RSRSWSYNGYYSDLSTARHSGHHKK 429
Query: 356 GRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKER 415
RK + + + + + + K R K+ KR S + K T R +S S+
Sbjct: 430 RRKEKKVKHKKKGK-KQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSS 488
Query: 416 EHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSR 475
+ SS+R+ ++ ++ SR SKS S SRS++ASK+ S S+SR
Sbjct: 489 SLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSR 548
Query: 476 SRSASRSPSRSRSRS 490
S+S S S S R R+
Sbjct: 549 SKSRSSSKSGHRKRA 563
Score = 78.6 bits (192), Expect = 1e-14
Identities = 100/371 (26%), Positives = 143/371 (38%), Gaps = 73/371 (19%)
Query: 193 RSRSRSRHSRKSRSRSGSSKSSHSKS-------RSRSRSGSRSRSKSRSRSQSRSRSKKE 245
+ R + HS S S S SS SS S S RSR R R RS+ + + S E
Sbjct: 187 KKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSE 246
Query: 246 KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQ 305
+ R +K + HS +S + K + + V +P+ P R
Sbjct: 247 EPR--NKHAMNPKGHSE-RSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPV 303
Query: 306 ERRVEEEKRGSVS-----RGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK------- 353
E K V+ + S KS R+ + R + + RSRS S+S D
Sbjct: 304 VTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPP 363
Query: 354 --------------------RKGRKRSREESRSRSRSRSKSERSRK-------------- 379
KG K S + SR RS S+RSR
Sbjct: 364 HWKEEMQRLRAYRPPSGEKWSKGDKLS-DPCSSRWDERSLSQRSRSWSYNGYYSDLSTAR 422
Query: 380 -----RGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV--------SKEREHAKSESSQRE 426
+ +++ K KK KK+ R ++ R + SK S RE
Sbjct: 423 HSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRE 482
Query: 427 GRGESENAGTNQET-RSRSRSNSKSKPNLPSESRS--RSKSASKTRSRSKSRSRSASRSP 483
S + ++ + R S+S+ + +L SR RSKS S++ SR SRSR+AS+S
Sbjct: 483 RSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSS 542
Query: 484 SRSRSRSHSRS 494
S SRSRS SRS
Sbjct: 543 SHSRSRSKSRS 553
Score = 77.8 bits (190), Expect = 2e-14
Identities = 76/219 (34%), Positives = 104/219 (47%), Gaps = 40/219 (18%)
Query: 203 KSRSRSGS-----SKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRS 257
K++ R GS K++ R R++ S S+SRS +SRS S+ KSR
Sbjct: 1269 KNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPS-RSRSKSETKSRH 1327
Query: 258 RSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSV 317
R+ S S S+S+ ++ S S ++S+S SRSRS RG
Sbjct: 1328 RTRSVSYSHSRSRSRS----------------STSSYRSRSYSRSRS---------RGWY 1362
Query: 318 SRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR-KGRKRSREESRSRSRSRSKSER 376
SRGR++ +S S RS + SRSRSRS S D + R + + SRSRSRS+S+R
Sbjct: 1363 SRGRTRSRS---SSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQR 1419
Query: 377 S----RKRGSKRDSKAGSSKKKKKE-DTDRSQSRSPSRS 410
S R R R S++ S E D S RSPS S
Sbjct: 1420 SDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSES 1458
Score = 76.3 bits (186), Expect = 6e-14
Identities = 89/292 (30%), Positives = 121/292 (41%), Gaps = 29/292 (9%)
Query: 212 KSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE---KSRSPSKEKSRSRSHSAGK---S 265
+SS S+S+ G + S + S S KKE KS+ +K G
Sbjct: 1179 ESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAP 1238
Query: 266 RSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRG-RSQE 324
+ + E K+ KP+ R + KSK++ R E K ++R R+QE
Sbjct: 1239 NAATSSAVEVKVLTTVPEMKPQGL---RIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQE 1295
Query: 325 KSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKR 384
S + SRS SRSRSKS+ K + R RS S SRSRSRS + R R R
Sbjct: 1296 SSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSR 1355
Query: 385 DSKAG---------SSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAG 435
G S + + R+ SRS SRS S + H++S S +
Sbjct: 1356 SRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYD-PHSRSRSYTYD--------S 1406
Query: 436 TNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKS-RSRSASRSPSRS 486
+RSRSRS + RS+S S S+S RS S RSPS S
Sbjct: 1407 YYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSES 1458
Score = 71.6 bits (174), Expect = 2e-12
Identities = 60/185 (32%), Positives = 90/185 (48%), Gaps = 12/185 (6%)
Query: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
+R P +S S ++ S++ ++ + S SR RS+ ++ + R+RS S SRSRSRS
Sbjct: 1288 NRRPRNQESSSDEQTPSRD---DDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSS 1344
Query: 348 SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSK-RDSKAGSSKKKKKEDTDRSQSRS 406
+ S RSR SRSRSR R+R R S R K+ + + + + S
Sbjct: 1345 TSS-------YRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHS 1397
Query: 407 PSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRS-RSNSKSKPNLPSESRSRSKSA 465
SRS + + +++S S R R +S + G + RSRS RS + S S RS S
Sbjct: 1398 RSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSE 1457
Query: 466 SKTRS 470
S S
Sbjct: 1458 SSRYS 1462
Score = 67.4 bits (163), Expect = 3e-11
Identities = 55/142 (38%), Positives = 70/142 (49%), Gaps = 22/142 (15%)
Query: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSR-KSRSRSG---SSKSSHSKSRSRSR 223
R + + SR S RSRS+SRSRSR +SR ++RSRS S KS + SRSRSR
Sbjct: 1330 RSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSR 1389
Query: 224 SG-----SRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQ 278
S SRSRS + SRSRS+ RS S + RS + + RS D +
Sbjct: 1390 SSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESD--- 1446
Query: 279 NNDNVGKPKSRSPSRHKSKSKS 300
RS S H+S S+S
Sbjct: 1447 ----------RSYSHHRSPSES 1458
Score = 65.9 bits (159), Expect = 8e-11
Identities = 78/348 (22%), Positives = 140/348 (40%), Gaps = 43/348 (12%)
Query: 150 YSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSR--KSRSR 207
YSD + T ++ R + + S +++ + HS S ++ HS+ K R R
Sbjct: 732 YSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDR 791
Query: 208 SGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS-----------RSRSKKEKSRSPSKEKSR 256
S S +S+SRS S S S +QS R+ +K+EK+R +EKS+
Sbjct: 792 S-SCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNR--GEEKSK 848
Query: 257 SRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGS 316
S + K+ + ++N KPK ++ + K S+S S ER V + +
Sbjct: 849 SERECPHSKKRTLKENLSDHLRNG---SKPKRKNYAGSKWDSESNS---ERDVTKNSKND 902
Query: 317 VSRGRSQEKSLRQSRSRS-----RSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSR 371
+E+ S S S K ++S + + D K S++ + +
Sbjct: 903 SHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEG 962
Query: 372 SKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQ------- 424
S S RG + K GS + K+E T + + + + K+++H + Q
Sbjct: 963 SCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGK---KDKKHKAPKRKQAFHWQPP 1019
Query: 425 ----REGRGESENAGTNQETRSR--SRSNSKSKPNLPSESRSRSKSAS 466
E E ++ QE++ + S +N K N+ +S + S
Sbjct: 1020 LEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLS 1067
Score = 65.1 bits (157), Expect = 1e-10
Identities = 55/139 (39%), Positives = 75/139 (53%), Gaps = 5/139 (3%)
Query: 181 RRRSYSRSRSHSRSRSRSRHSR-KSRSRSGS-SKSSHSKSRSRSRSGSRSRSKSRSRSQS 238
R R+ S S SHSRSRSRS S +SRS S S S+ +S+ R+RSRS S RS R+ S
Sbjct: 1326 RHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSS-YRSYKSHRTSS 1384
Query: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298
RSRS+ S+ +S + +SRS+S+ Q + + + +SRS + S S
Sbjct: 1385 RSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNR-RSRSCRSYGSDS 1443
Query: 299 KS-RSRSQERRVEEEKRGS 316
+S RS S R E R S
Sbjct: 1444 ESDRSYSHHRSPSESSRYS 1462
Score = 47.4 bits (111), Expect = 3e-05
Identities = 47/202 (23%), Positives = 80/202 (39%), Gaps = 17/202 (8%)
Query: 308 RVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSR 367
++E K + SR + + + ++S + R + + S S S
Sbjct: 152 QIENLKTDAASRPYADVRVIDCGVLATKSIKDVFEKKRKKPTHSEGSDSSSNSSSSSESS 211
Query: 368 SRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRS---------PSRSVSKEREHA 418
S S + ERSR+R KR K SKK++KE + + R+ RS + E+
Sbjct: 212 SESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSV 271
Query: 419 KSESSQREGRGESENAGTNQETRSRSRSN-----SKSKPNLPSES---RSRSKSASKTRS 470
S + + + E E R R + ++ +P +P + + S SK+
Sbjct: 272 DSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGR 331
Query: 471 RSKSRSRSASRSPSRSRSRSHS 492
+ K R +P RSRS S S
Sbjct: 332 KIKGRGTIRYHTPPRSRSCSES 353
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 101 bits (252), Expect = 1e-21
Identities = 65/199 (32%), Positives = 103/199 (51%), Gaps = 9/199 (4%)
Query: 229 RSKSRSRSQSRSRS---KKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGK 285
+ K R R++ R KKEK +EK R R + + + +++ EK + D +
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
Query: 286 PKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSR 345
+SRS SRH S++ R S+ R + + R RS+++ +S RS K SRSR R
Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350
Query: 346 SRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGS--KRDSKAGSSKKKKKEDTDRSQ 403
RSKS+D++ + RS+ R + R KS+ KRGS K+ S S++K+ EDT+
Sbjct: 351 RRSKSRDRKSYKHRSKSRDREQDR---KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTES 407
Query: 404 SRSPSRS-VSKEREHAKSE 421
S +++ V+ E KSE
Sbjct: 408 KESDTKNEVNGTSEDIKSE 426
Score = 92.0 bits (227), Expect = 1e-18
Identities = 65/206 (31%), Positives = 103/206 (50%), Gaps = 14/206 (6%)
Query: 252 KEKSRSRSHSAGKSR--SKSKDQAEEKIQNNDNVGKPKSRSPSRHKS-KSKSRSRSQERR 308
KEK R R+ + K K + EE+ + + + + R R + + K R+R +ERR
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
Query: 309 VEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREE----S 364
+ S SR R ++ + SRSR SRSR R RS+S+D+R+ R R E S
Sbjct: 291 -----KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRS 345
Query: 365 RSRSRSRSKS--ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSES 422
RSR R RSKS +S K SK + K K+KE +S +S S+E++ + +
Sbjct: 346 RSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405
Query: 423 SQREGRGESENAGTNQETRSRSRSNS 448
+E ++E GT+++ +S + S
Sbjct: 406 ESKESDTKNEVNGTSEDIKSEGDTQS 431
Score = 89.4 bits (220), Expect = 7e-18
Identities = 67/212 (31%), Positives = 107/212 (50%), Gaps = 18/212 (8%)
Query: 266 RSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEK 325
+ K + + EE ++ + K K R K + + R + +R EE+ R R +E
Sbjct: 231 KEKLRKRTEEP-DRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE- 288
Query: 326 SLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRS----KSERSRKRG 381
R+ RSRSRS+ SR+ R S+S+D ++ R R R SRSR R RS +SER +
Sbjct: 289 --RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSR 346
Query: 382 SKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSE---SSQREGRGESENAGTNQ 438
S+ ++ S +K + +S+ R R SKE+E S+ SS + G E ++ TN
Sbjct: 347 SRDRRRSKSRDRKSYKHRSKSRDREQDRK-SKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405
Query: 439 ETRSRSRSNSKSKPNLPSESRSRSKSASKTRS 470
E++ S++K++ N SE KS T+S
Sbjct: 406 ESK---ESDTKNEVNGTSED---IKSEGDTQS 431
Score = 88.6 bits (218), Expect = 1e-17
Identities = 62/209 (29%), Positives = 97/209 (46%), Gaps = 8/209 (3%)
Query: 254 KSRSRSHSAGKSR---SKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVE 310
+SR H GK +K K EE + + R K K + R +ER E
Sbjct: 205 QSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERE 264
Query: 311 EEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRS 370
E+R R +E+ ++R R R K SRSRSR S++ D+R R R + SRSR R
Sbjct: 265 REERERKRRREEEEREKERARDRERRKR-SRSRSRHSSRTSDRRCSRSRDHKRSRSRERR 323
Query: 371 RSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE 430
RS+S R R+R D S +K + DR +S+S R K R ++ R+ + +
Sbjct: 324 RSRS-RDRRRSRSHDR---SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK 379
Query: 431 SENAGTNQETRSRSRSNSKSKPNLPSESR 459
+ ++++ +S S K + +ES+
Sbjct: 380 EKRGSDDKKSSVKSGSREKQSEDTNTESK 408
Score = 83.6 bits (205), Expect = 4e-16
Identities = 57/154 (37%), Positives = 82/154 (53%), Gaps = 10/154 (6%)
Query: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227
++ R E++ R R R RS SRSR SR S + SRS H +SRSR R SR
Sbjct: 271 KRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRS----RDHKRSRSRERRRSR 326
Query: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKD-----QAEEKIQNNDN 282
SR + RSRS RS +K +SRS + +S+SR + K RSKS+D +++EK + +
Sbjct: 327 SRDRRRSRSHDRS-ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
Query: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGS 316
K +S SR K + + S+E + E G+
Sbjct: 386 DKKSSVKSGSREKQSEDTNTESKESDTKNEVNGT 419
Score = 80.5 bits (197), Expect = 3e-15
Identities = 66/265 (24%), Positives = 114/265 (43%), Gaps = 49/265 (18%)
Query: 146 EFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSR 205
+ + Y+ +K +E+L K+R ++P R + R + R R +
Sbjct: 216 QHMGYAKIKATVEELK------EKLRKRTEEPDRDERLKKEKQEREEREKEREREREERE 269
Query: 206 SRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKS 265
+ + K R+R R R RS+SRSR SR+ S + SRS ++SRSR +
Sbjct: 270 RKRRREEEEREKERARDRE-RRKRSRSRSRHSSRT-SDRRCSRSRDHKRSRSRE----RR 323
Query: 266 RSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEK 325
RS+S+D + RS S +S+ K RSRS++RR
Sbjct: 324 RSRSRD---------------RRRSRSHDRSERKHRSRSRDRR----------------- 351
Query: 326 SLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRD 385
RS+SR + + RS+SR + +D++ K R +S +S S + + +
Sbjct: 352 -----RSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTE 406
Query: 386 SKAGSSKKKKKEDTDRSQSRSPSRS 410
SK +K + ++ +S ++S
Sbjct: 407 SKESDTKNEVNGTSEDIKSEGDTQS 431
Score = 78.2 bits (191), Expect = 2e-14
Identities = 58/208 (27%), Positives = 91/208 (43%), Gaps = 13/208 (6%)
Query: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342
VG +SR K + VEE K R ++ R + + + +
Sbjct: 201 VGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKE 260
Query: 343 RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
R R R + + KR+ + RE+ R+R R R K RSR R S R S S+ + D RS
Sbjct: 261 REREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSR---DHKRS 317
Query: 403 QSRSPSRSVSKEREHAKS-ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSR 461
+SR RS S++R ++S + S+R+ R S R R RS S+ + + S+SR
Sbjct: 318 RSRERRRSRSRDRRRSRSHDRSERKHRSRS---------RDRRRSKSRDRKSYKHRSKSR 368
Query: 462 SKSASKTRSRSKSRSRSASRSPSRSRSR 489
+ + + R +S +S SR
Sbjct: 369 DREQDRKSKEKEKRGSDDKKSSVKSGSR 396
Score = 72.4 bits (176), Expect = 9e-13
Identities = 46/230 (20%), Positives = 103/230 (44%), Gaps = 6/230 (2%)
Query: 269 SKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQE----RRVEEEKRGSVSRGRSQE 324
++ + ++ + ++G K ++ + + K K R R++E R+++EK+ R + +E
Sbjct: 204 AQSRVDDHLMGKQHMGYAKIKA-TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERE 262
Query: 325 KSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKR 384
+ + + R + R + R+R + + KR R RSR SR+ R S+S ++ S+
Sbjct: 263 REREERERKRRREEEEREKERARDRERRKRS-RSRSRHSSRTSDRRCSRSRDHKRSRSRE 321
Query: 385 DSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRS 444
++ S +++ DRS+ + SRS + R ++ S + + +
Sbjct: 322 RRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEK 381
Query: 445 RSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
R + K ++ S SR + + T S+ + + +S ++S
Sbjct: 382 RGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
Score = 54.7 bits (130), Expect = 2e-07
Identities = 44/124 (35%), Positives = 58/124 (46%), Gaps = 25/124 (20%)
Query: 181 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR------SKSRS 234
R R + RSRS R RSRSR R+SRS S + S+SR R RS SR R SKSR
Sbjct: 310 RSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRD 369
Query: 235 RSQSRSRSKKEKSRSP-----------------SKEKSRSRSHSAGKSRSKSKD-QAEEK 276
R Q R +KEK S + +S+ S + + S+D ++E
Sbjct: 370 REQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESK-ESDTKNEVNGTSEDIKSEGD 428
Query: 277 IQNN 280
Q+N
Sbjct: 429 TQSN 432
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 101 bits (252), Expect = 1e-21
Identities = 115/426 (26%), Positives = 173/426 (40%), Gaps = 101/426 (23%)
Query: 158 EKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSK 217
E++ ++ K+ ++ + + +R S R RSR R+ +SRS S + S
Sbjct: 129 EEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSP 188
Query: 218 -SRSRSRSGSRS-RSKSRSRSQSRSRSKKEKS---------------------------- 247
R R RS SRS R +++SRS S + KKEK+
Sbjct: 189 VRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVP 248
Query: 248 --------RSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPS----RHK 295
+ PS EK+ + K+R +S+ +++ + + +SRSPS R +
Sbjct: 249 KPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSR-------SRTRSRSPSHTRPRRR 301
Query: 296 SKSKSRSRSQERRVEEEKRGSVSR-------------GRSQEKSLRQSRSRSRSKGGSRS 342
+S+SRS S RR +R S R RS+ R+ RS + G S S
Sbjct: 302 HRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSS 361
Query: 343 RSRSRSKSKDK----------RKGRKRSREESRSRSRSR-----------------SKSE 375
S SRS+S K RK R+ S S R R R +S
Sbjct: 362 SSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSN 421
Query: 376 RSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAG 435
R+RK S K K + T++ +S SP+ K R+ SES + +G G+ A
Sbjct: 422 RTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPA---PKPRKVELSESEEDKG-GKMAAAD 477
Query: 436 TNQETRSRSRSNSKSKPNLPSES--------RSRSKSASKTRSRSKSRSRSASRSPSRSR 487
+ Q+ R R N +S + S S RS K+ R R S SRSAS SP + +
Sbjct: 478 SVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQ 537
Query: 488 SRSHSR 493
+ R
Sbjct: 538 KETSPR 543
Score = 91.7 bits (226), Expect = 1e-18
Identities = 90/328 (27%), Positives = 134/328 (40%), Gaps = 26/328 (7%)
Query: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGS-RSRSKS 232
E P ++ + ++ RSRSRS+ ++RSRS S + RSRSRS S R R
Sbjct: 258 EPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSP 317
Query: 233 RSRSQSRSRS---------KKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
R R R R+ + +SRSP + + RS + +G S S S ++ +
Sbjct: 318 RRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKK---- 373
Query: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSR 343
PK S K++ S S S RR + +++ Q +R+R S S
Sbjct: 374 -PPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSP 432
Query: 344 SRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQ 403
R+ K + KR + R SE +G K + A S +++++ Q
Sbjct: 433 GRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM-AAADSVQQRRQYRRQNQQ 491
Query: 404 SRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNS---KSKPNLPSESRS 460
S S S S S + S + G E + + SRS S S + K P R
Sbjct: 492 SSSDSGSSSSSEDERPKRSHVKNG----EVGRRRRHSPSRSASPSPRKRQKETSPRGRRR 547
Query: 461 RSKSASKTRSRSKSRSRSASRSPSRSRS 488
RS S TR R RS S + P R R+
Sbjct: 548 RSPSPPPTRRR---RSPSPAPPPRRRRT 572
Score = 82.4 bits (202), Expect = 9e-16
Identities = 82/306 (26%), Positives = 130/306 (42%), Gaps = 18/306 (5%)
Query: 181 RRRSYSRSRSHSRSRSRSRHSRKS-RSRSGSSKSSHSKSRSRSRSGSRSRSK-SRSRSQS 238
RRR SRSRS+S R S R S R R+ + RSRS R R + S S S S
Sbjct: 299 RRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGS 358
Query: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP--SRHKS 296
S S +SRSP K+ + S K+R S + + ++ + P + P +RH
Sbjct: 359 SSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPS---PPATPPPKTRHSP 415
Query: 297 KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSR--SRSKSKDKR 354
+ +R+++ RV SVS GR+ K + + R + R S+S++ +
Sbjct: 416 TPQQSNRTRKSRV------SVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDK 469
Query: 355 KGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKK---KKEDTDRSQSRSPSRSV 411
G+ + + + R + R ++++S S K+ K + R + SPSRS
Sbjct: 470 GGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSA 529
Query: 412 SKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSR 471
S + E+S R R S + + RS S + + P+ R + R R
Sbjct: 530 SPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRR 589
Query: 472 SKSRSR 477
S S R
Sbjct: 590 SPSPRR 595
Score = 69.3 bits (168), Expect = 7e-12
Identities = 105/410 (25%), Positives = 159/410 (38%), Gaps = 53/410 (12%)
Query: 125 RQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRL---VEDKPGSRR 181
R +G+VT HKG + E S + R +E + E G K+ V+ + RR
Sbjct: 434 RTSGKVT---KHKGTEKR---ESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRR 487
Query: 182 RRSYSRSRSHSRSRSRSRHSRKSRSRSGS--SKSSHSKSRSRSRSGSRSRSKS-----RS 234
+ S S S S S S ++S ++G + HS SRS S S + + ++ R
Sbjct: 488 QNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRR 547
Query: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAG----------KSRSKSKDQAEEKIQNNDNVG 284
RS S +++ +S SP+ R R+ + + RS S + IQ +
Sbjct: 548 RSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPS 607
Query: 285 KPKSR---SPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSR 341
P R SP + S S +RRV R K S S KG S
Sbjct: 608 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPK-QRSSPVTKRRSPSLSSKHRKGSSP 666
Query: 342 SRS--RSRSKSKDKRKG---RKRSREESRS---------RSRSRSKSERSRKRGSKRDSK 387
SRS +RS +KR R R+ + S S S R +S R +R S+
Sbjct: 667 SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR 726
Query: 388 AGSSKKKKKEDTDRSQSR---SPSRSVSKEREHAKSESSQREGRGESENAGTNQE----- 439
KK KK + QS S SRSVS E A + +S++ TN
Sbjct: 727 TPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPV 786
Query: 440 TRSRSRSNSKSKP-NLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRS 488
+++S + S S P N E + K K + K + + + ++
Sbjct: 787 KKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKA 836
Score = 67.4 bits (163), Expect = 3e-11
Identities = 75/267 (28%), Positives = 118/267 (44%), Gaps = 45/267 (16%)
Query: 243 KKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS-R 301
KKE+ + E+ + S K + + KD+ +++ + + + +SRSP R KS+S S R
Sbjct: 127 KKEEIKQRQIEQEKLASM---KKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPR 183
Query: 302 SRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGS-RSRSRSRSKSKDKRKGRKRS 360
RS R E R RS +S R R++SRS + + ++ + K ++ S
Sbjct: 184 RRSSPVRRE--------RKRSHSRSPRH-RTKSRSPSPAPEKKEKTPELPEPSVKVKEPS 234
Query: 361 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS 420
+E+ S S + K S +SKK+K+++ R +SRS S+S S+ R + S
Sbjct: 235 VQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPS 294
Query: 421 ESSQREGRGESENAGTNQETRSRSRSNS-------------------KSKPNLPSESRSR 461
+ R + RSRSRS S + P P RSR
Sbjct: 295 HTRPR------------RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSR 342
Query: 462 SKSASKTRSRSKSRSRSASRSPSRSRS 488
S + RS + S+S S SRSRS
Sbjct: 343 SPVRRRRRSSASLSGSSSSSSSSRSRS 369
Score = 63.2 bits (152), Expect = 5e-10
Identities = 85/338 (25%), Positives = 132/338 (39%), Gaps = 37/338 (10%)
Query: 186 SRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE 245
+R+R S S R S K G+ K + R S S+ + + +
Sbjct: 421 NRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQ 480
Query: 246 KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQ 305
+ R ++ +S S S S S+ + ++N + VG+ + SPSR S S +
Sbjct: 481 QRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGE-VGRRRRHSPSRSASPSP-----R 534
Query: 306 ERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS-----RSRSKSKDKRKGRKRS 360
+R+ E RG R S + R+ RS S + R R+ R R+ S R+
Sbjct: 535 KRQKETSPRGRRRRSPSPPPT-RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
Query: 361 REESRSRSRSRSKSERSRKRGS-------KRDSKAGSSKKK-------KKEDTDRSQSRS 406
R S R S S ++R + +R S + K++ K+ + ++ RS
Sbjct: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRS 653
Query: 407 PSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNL-----PSESRSR 461
PS S SK R+ + S RE R N + R R+ S S P + S R +
Sbjct: 654 PSLS-SKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQ 712
Query: 462 SKSASKTRSRSKSRSRSASR-----SPSRSRSRSHSRS 494
S S S R SR+ + SPS R S S
Sbjct: 713 SPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSS 750
Score = 61.6 bits (148), Expect = 2e-09
Identities = 87/338 (25%), Positives = 123/338 (36%), Gaps = 36/338 (10%)
Query: 186 SRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR---SKSRSRSQSRSRS 242
+R S S S R RH R S + K+ HS + +S +SR S R+ +
Sbjct: 385 TRRLSPSASPPRRRH-RPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHK 443
Query: 243 KKEKSRSPSK-------EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHK 295
EK SPS E S S GK + Q + + + S S S +
Sbjct: 444 GTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE 503
Query: 296 SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRK 355
+ RS + V +R S SR S RQ + R G R RS S ++ +R
Sbjct: 504 DERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPR---GRRRRSPSPPPTRRRRS 560
Query: 356 G------RKRSREESRSRSRSRSKSERSRKRGSKRDS-------------KAGSSKKKKK 396
R+R R R+ S R R +R S K ++
Sbjct: 561 PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP 620
Query: 397 EDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPS 456
S S P R VS K SS R + +++ S SRS +++ P+
Sbjct: 621 PKRRASPSPPPKRRVS-HSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPN 679
Query: 457 ESRSRS--KSASKTRSRSKSRSRSASRSPSRSRSRSHS 492
+ S S A +T S R AS SP R +S S S
Sbjct: 680 KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPS 717
Score = 55.5 bits (132), Expect = 1e-07
Identities = 83/347 (23%), Positives = 126/347 (36%), Gaps = 31/347 (8%)
Query: 168 RKIRLVEDKPGSRRRRSYS---RSRSHS-----RSRSRSRHSRKSRSRSGSSKSSHSKSR 219
R+ R P RRRR+ + R R+ S RS S R+S + R S ++
Sbjct: 556 RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA 615
Query: 220 SRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRS----HSAGKSRSKSKDQAEE 275
S R S S + S S K RS K RS S H G S S+S +A
Sbjct: 616 SPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARS 675
Query: 276 KIQNNDNVGKPKSRSPSRHKSKSKSR----SRSQERRVEEEKRGSVSRGRSQEKSLRQSR 331
N + P+ R+P S R S Q R+ + R + + +
Sbjct: 676 PQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKK 735
Query: 332 SRSRSKGGSRSRSRSRSKSKDKRKGRKR-----SREESRSRSRSRSKSERSRKRGS---- 382
+ S S R S SRS S K+ S +S+S S + S + +K S
Sbjct: 736 AASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPS 795
Query: 383 -----KRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTN 437
D + G KKKKK+D + + + ++E A + ++ + A T
Sbjct: 796 PSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATT 855
Query: 438 QETRSRSRSNSKSKPNLPSESRSRSKSASK-TRSRSKSRSRSASRSP 483
+ + + K SE+ K R ++ R A SP
Sbjct: 856 TLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRKAQVSP 902
Score = 34.3 bits (77), Expect = 0.27
Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 9/74 (12%)
Query: 430 ESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPS----- 484
+ E Q + + S K + + +S+ + R RS+S R SRSPS
Sbjct: 127 KKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRS 186
Query: 485 ----RSRSRSHSRS 494
R R RSHSRS
Sbjct: 187 SPVRRERKRSHSRS 200
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.119 0.310
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,682,407
Number of Sequences: 37866
Number of extensions: 853796
Number of successful extensions: 48141
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 955
Number of HSP's successfully gapped in prelim test: 1252
Number of HSP's that attempted gapping in prelim test: 7452
Number of HSP's gapped (non-prelim): 12419
length of query: 494
length of database: 18,247,518
effective HSP length: 106
effective length of query: 388
effective length of database: 14,233,722
effective search space: 5522684136
effective search space used: 5522684136
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.