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Search of human proteins with 213385278
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|213385278 TNF receptor-associated factor 3 interacting
protein 1 isoform 2 [Homo sapiens]
(625 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|213385278 TNF receptor-associated factor 3 interacting protei... 1225 0.0
gi|20070262 TNF receptor-associated factor 3 interacting protein... 1124 0.0
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 114 2e-25
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 114 4e-25
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 114 4e-25
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 108 1e-23
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 105 2e-22
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 103 5e-22
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 101 2e-21
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 98 2e-20
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 94 4e-19
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 93 6e-19
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 93 8e-19
gi|52426743 cisplatin resistance-associated overexpressed protei... 89 1e-17
gi|19923485 cisplatin resistance-associated overexpressed protei... 89 1e-17
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 89 2e-17
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 85 2e-16
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 81 3e-15
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 81 3e-15
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 81 3e-15
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 81 3e-15
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 80 4e-15
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 80 6e-15
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 80 6e-15
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 79 1e-14
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 78 3e-14
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 77 4e-14
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 77 6e-14
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 77 6e-14
gi|34878777 ring finger protein 20 [Homo sapiens] 76 1e-13
>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
isoform 2 [Homo sapiens]
Length = 625
Score = 1225 bits (3170), Expect = 0.0
Identities = 625/625 (100%), Positives = 625/625 (100%)
Query: 1 MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKS 60
MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKS
Sbjct: 1 MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKS 60
Query: 61 DNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLS 120
DNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLS
Sbjct: 61 DNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLS 120
Query: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR 180
SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR
Sbjct: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR 180
Query: 181 DRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD 240
DRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD
Sbjct: 181 DRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD 240
Query: 241 RDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD 300
RDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD
Sbjct: 241 RDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD 300
Query: 301 KPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSD 360
KPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSD
Sbjct: 301 KPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSD 360
Query: 361 AEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSG 420
AEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSG
Sbjct: 361 AEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSG 420
Query: 421 SGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILE 480
SGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILE
Sbjct: 421 SGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILE 480
Query: 481 TKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPLGKIMDY 540
TKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPLGKIMDY
Sbjct: 481 TKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPLGKIMDY 540
Query: 541 IQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQQDKICA 600
IQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQQDKICA
Sbjct: 541 IQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQQDKICA 600
Query: 601 VKANILKNEEKIQKMVYSINLTSRR 625
VKANILKNEEKIQKMVYSINLTSRR
Sbjct: 601 VKANILKNEEKIQKMVYSINLTSRR 625
>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
isoform 1 [Homo sapiens]
Length = 691
Score = 1124 bits (2908), Expect = 0.0
Identities = 593/691 (85%), Positives = 605/691 (87%), Gaps = 66/691 (9%)
Query: 1 MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKS 60
MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKS
Sbjct: 1 MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKS 60
Query: 61 DNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLS 120
DNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLS
Sbjct: 61 DNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLS 120
Query: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR 180
SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR
Sbjct: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR 180
Query: 181 DRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD 240
DRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD
Sbjct: 181 DRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD 240
Query: 241 RDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD 300
RDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD
Sbjct: 241 RDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD 300
Query: 301 KPEKKSASSG--------------------EMSKKLSDG-TFKDSKAETETEISTRASKS 339
KPEKKSASSG E+S + S T K SK ++ + R +
Sbjct: 301 KPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDN 360
Query: 340 LTTKT----------------------SKRRSKNSV-----------------------E 354
++ K+ +K + NS +
Sbjct: 361 ISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQK 420
Query: 355 GDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEAL 414
GDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEAL
Sbjct: 421 GDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEAL 480
Query: 415 QMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGL 474
QMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGL
Sbjct: 481 QMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGL 540
Query: 475 VKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPL 534
VKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPL
Sbjct: 541 VKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPL 600
Query: 535 GKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQ 594
GKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQ
Sbjct: 601 GKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQ 660
Query: 595 QDKICAVKANILKNEEKIQKMVYSINLTSRR 625
QDKICAVKANILKNEEKIQKMVYSINLTSRR
Sbjct: 661 QDKICAVKANILKNEEKIQKMVYSINLTSRR 691
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 114 bits (286), Expect = 2e-25
Identities = 90/351 (25%), Positives = 167/351 (47%), Gaps = 36/351 (10%)
Query: 151 NKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGN 210
+K + EE+ + K +R + E + R R+R+++ E +E + RE+++++EK KE
Sbjct: 288 HKKLEEEKGKKEK---ERQEIEKERRERERERERERERREREREREREREREKEKERERE 344
Query: 211 RHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERD 270
R R+ +R+R K ER +DR +RERDRD +R++ ++R + + +E+ RDR+RER+
Sbjct: 345 RERDRDRDRTK-------ERDRDR-DRERDRDRDRERSSDRNKDRSRSREKSRDRERERE 396
Query: 271 RDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETET 330
R++ ++R+R R + E + +RE+ RE +K +K+ E + ++ K E +
Sbjct: 397 REREREREREREREREREREREREREREREKDKKRDREEDE------EDAYERRKLERKL 450
Query: 331 EISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIR 390
A + R K + E + +AE + + E E + + R
Sbjct: 451 REKEAAYQERLKNWEIRERKKTREYE--KEAEREEERRREMAKEAKRLKEFLEDYDDD-R 507
Query: 391 RIPRPGSARPAPPRVK-RQDSMEALQMDRSGSGKTVSNV----ITESHNSDNEEDDQFVV 445
P+ R++ R+ MEA + DR + + + + E H + E +
Sbjct: 508 DDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQ 567
Query: 446 EA----APQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSP 492
EA PQ+ + E E EEEE+ +K E ++ E+ +Q P
Sbjct: 568 EAERRRQPQIKQEPESE-------EEEEEKQEKEEKREEPMEEEEEPEQKP 611
Score = 75.9 bits (185), Expect = 1e-13
Identities = 77/294 (26%), Positives = 124/294 (42%), Gaps = 70/294 (23%)
Query: 145 RSQELDNKNVREEE-SRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEK 203
R++E D RE + R + + DR + R SRDR+++ E + +R+ RE+++++E+
Sbjct: 353 RTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERE-RERERERER 411
Query: 204 AKENGGNRHREGERERAKARARPDNE-------------RQKDRGNRER----------- 239
+E R RE ERE+ K R R ++E R+K+ +ER
Sbjct: 412 EREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKK 471
Query: 240 --DRDSERKKETERKSEGGKEKERLR--------DRD------------RERDRDK---G 274
+ + E ++E ER+ E KE +RL+ DRD R RDR+K
Sbjct: 472 TREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEA 531
Query: 275 KDRDRRRVKN----------GEHSWDLDREKNREHDKPEKKSA--------SSGEMSKKL 316
+RDR+R K E D D E R + E++ S E +K
Sbjct: 532 DERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQ 591
Query: 317 SDGTFKDSKAETETEISTRASKSLTTKT-SKRRSKNSVEGDSTSDAEGDAGPAG 369
++ E E E + T + S S +S G++T + GD P G
Sbjct: 592 EKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCG 645
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 114 bits (284), Expect = 4e-25
Identities = 89/321 (27%), Positives = 155/321 (48%), Gaps = 36/321 (11%)
Query: 130 AGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELK 189
+G+ E KG S S ++ + + R ++ R + + RS +DR++ K
Sbjct: 297 SGKSNERKGGRS-RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRS---K 352
Query: 190 EDRKPREKDKDKEKAKENGGNRH-REGERERAKARARPDNERQKDRGNRERDRDSERKKE 248
K R K +++ K++ +R R+ RE+ K + R ++KDR +ER+R+ ER+KE
Sbjct: 353 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERV---KEKDR-EKEREREKEREKE 408
Query: 249 TERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSAS 308
ER GK K+ RD++RE+DR+K K++DR R + EH D D+EK +E DK +++
Sbjct: 409 KER----GKNKD--RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK- 461
Query: 309 SGEMSKKLSDGTFKDSKAET--ETEISTRASKSLTTKTSKRRSKNSVEGDSTSDA---EG 363
+ SK++ + KD K+ T + ++R S+S + + +RRS++S TS +
Sbjct: 462 --DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS 519
Query: 364 DAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGK 423
P+ + +++ + E + S R +R SM DR G K
Sbjct: 520 SRSPSPRSRNKKDKKREKERDHISERR-------------ERERSTSMRKSSNDRDGKEK 566
Query: 424 TVSNVITESHNSDNEEDDQFV 444
N + N+E D V
Sbjct: 567 LEKNSTSLKEKEHNKEPDSSV 587
Score = 100 bits (248), Expect = 5e-21
Identities = 79/326 (24%), Positives = 155/326 (47%), Gaps = 22/326 (6%)
Query: 133 KGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDR------GDAEIKERSTSRDRKQKE 186
+ + ++ +S+S ++ + SR H + R + K+RS SR+R++
Sbjct: 309 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR 368
Query: 187 ELKEDRKPR----EKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRD 242
R R EK K+KE+ KE + RE E+ER K + R N KDR ++ER++D
Sbjct: 369 SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN---KDR-DKEREKD 424
Query: 243 SERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKP 302
E+ KE +R+ E KE E+ RD+++E+++DK K+R++ R K D R+K+++ P
Sbjct: 425 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK----EIDEKRKKDKKSRTP 480
Query: 303 EKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAE 362
+ +S + + S++ + + +++ K ++++ RS+N + D + E
Sbjct: 481 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRN--KKDKKREKE 538
Query: 363 GDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSG 422
D +++ + N+ ++ + ++ K DS + ++D +
Sbjct: 539 RDHISERRERERSTSMRKSSNDRDGK-EKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAP 597
Query: 423 KTVSNVITESHNSD-NEEDDQFVVEA 447
+T N I + N NEE+ EA
Sbjct: 598 RTEENKIQHNGNCQLNEENLSTKTEA 623
Score = 33.1 bits (74), Expect = 0.79
Identities = 49/224 (21%), Positives = 86/224 (38%), Gaps = 16/224 (7%)
Query: 300 DKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVE---GD 356
D+P K + S+ + K +K E R ++S + + S S E G
Sbjct: 248 DRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGR 307
Query: 357 STSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQM 416
S S + + + S + S N R + R P KR S E +
Sbjct: 308 SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER-RK 366
Query: 417 DRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMS-EIEMVTAVELEEEEKHGGLV 475
RS SH+ D +D + ++ ++ E E E E E+E++ G
Sbjct: 367 SRS-----------RSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 415
Query: 476 KKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEK 519
+ E +KD EK ++ + E+E+ + K+++ KE E+
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 459
Score = 33.1 bits (74), Expect = 0.79
Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 13/130 (10%)
Query: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRV----HKNTEDRGDAEIKER 176
S +A RR + + + R+ +SRS +K ++ + SR +N +D+ KER
Sbjct: 483 SYNASRRSRSSSRERRRRRSRSSSRSPR-TSKTIKRKSSRSPSPRSRNKKDK--KREKER 539
Query: 177 STSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGN 236
+R+++E RK KEK ++N + E+E K PD+ K+ +
Sbjct: 540 DHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLK---EKEHNK---EPDSSVSKEVDD 593
Query: 237 RERDRDSERK 246
++ R E K
Sbjct: 594 KDAPRTEENK 603
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 114 bits (284), Expect = 4e-25
Identities = 89/321 (27%), Positives = 155/321 (48%), Gaps = 36/321 (11%)
Query: 130 AGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELK 189
+G+ E KG S S ++ + + R ++ R + + RS +DR++ K
Sbjct: 181 SGKSNERKGGRS-RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRS---K 236
Query: 190 EDRKPREKDKDKEKAKENGGNRH-REGERERAKARARPDNERQKDRGNRERDRDSERKKE 248
K R K +++ K++ +R R+ RE+ K + R ++KDR +ER+R+ ER+KE
Sbjct: 237 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERV---KEKDR-EKEREREKEREKE 292
Query: 249 TERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSAS 308
ER GK K+ RD++RE+DR+K K++DR R + EH D D+EK +E DK +++
Sbjct: 293 KER----GKNKD--RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK- 345
Query: 309 SGEMSKKLSDGTFKDSKAET--ETEISTRASKSLTTKTSKRRSKNSVEGDSTSDA---EG 363
+ SK++ + KD K+ T + ++R S+S + + +RRS++S TS +
Sbjct: 346 --DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS 403
Query: 364 DAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGK 423
P+ + +++ + E + S R +R SM DR G K
Sbjct: 404 SRSPSPRSRNKKDKKREKERDHISERR-------------ERERSTSMRKSSNDRDGKEK 450
Query: 424 TVSNVITESHNSDNEEDDQFV 444
N + N+E D V
Sbjct: 451 LEKNSTSLKEKEHNKEPDSSV 471
Score = 100 bits (248), Expect = 5e-21
Identities = 79/326 (24%), Positives = 155/326 (47%), Gaps = 22/326 (6%)
Query: 133 KGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDR------GDAEIKERSTSRDRKQKE 186
+ + ++ +S+S ++ + SR H + R + K+RS SR+R++
Sbjct: 193 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR 252
Query: 187 ELKEDRKPR----EKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRD 242
R R EK K+KE+ KE + RE E+ER K + R N KDR ++ER++D
Sbjct: 253 SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN---KDR-DKEREKD 308
Query: 243 SERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKP 302
E+ KE +R+ E KE E+ RD+++E+++DK K+R++ R K D R+K+++ P
Sbjct: 309 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK----EIDEKRKKDKKSRTP 364
Query: 303 EKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAE 362
+ +S + + S++ + + +++ K ++++ RS+N + D + E
Sbjct: 365 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRN--KKDKKREKE 422
Query: 363 GDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSG 422
D +++ + N+ ++ + ++ K DS + ++D +
Sbjct: 423 RDHISERRERERSTSMRKSSNDRDGK-EKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAP 481
Query: 423 KTVSNVITESHNSD-NEEDDQFVVEA 447
+T N I + N NEE+ EA
Sbjct: 482 RTEENKIQHNGNCQLNEENLSTKTEA 507
Score = 33.1 bits (74), Expect = 0.79
Identities = 49/224 (21%), Positives = 86/224 (38%), Gaps = 16/224 (7%)
Query: 300 DKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVE---GD 356
D+P K + S+ + K +K E R ++S + + S S E G
Sbjct: 132 DRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGR 191
Query: 357 STSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQM 416
S S + + + S + S N R + R P KR S E +
Sbjct: 192 SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER-RK 250
Query: 417 DRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMS-EIEMVTAVELEEEEKHGGLV 475
RS SH+ D +D + ++ ++ E E E E E+E++ G
Sbjct: 251 SRS-----------RSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 299
Query: 476 KKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEK 519
+ E +KD EK ++ + E+E+ + K+++ KE E+
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 343
Score = 33.1 bits (74), Expect = 0.79
Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 13/130 (10%)
Query: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRV----HKNTEDRGDAEIKER 176
S +A RR + + + R+ +SRS +K ++ + SR +N +D+ KER
Sbjct: 367 SYNASRRSRSSSRERRRRRSRSSSRSPR-TSKTIKRKSSRSPSPRSRNKKDK--KREKER 423
Query: 177 STSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGN 236
+R+++E RK KEK ++N + E+E K PD+ K+ +
Sbjct: 424 DHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLK---EKEHNK---EPDSSVSKEVDD 477
Query: 237 RERDRDSERK 246
++ R E K
Sbjct: 478 KDAPRTEENK 487
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 108 bits (270), Expect = 1e-23
Identities = 59/234 (25%), Positives = 124/234 (52%), Gaps = 7/234 (2%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
E+ K R +R + + + RE+E++ +RG +ER T + ++K + +
Sbjct: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Query: 192 R-KPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKE-- 248
R + R+ ++++EK E RE ER++ + R R D +R +DR +ER+R ++RK++
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERER-DRDRDRDRRQKERERQTDRKRQRR 290
Query: 249 TERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSAS 308
TER E +++ER R+R+RER+R++ ++R+R R + E + +R++ +E ++ K+
Sbjct: 291 TERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQT- 349
Query: 309 SGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAE 362
EM ++ + T ++ + + E E + + + + + D + E
Sbjct: 350 --EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE 401
Score = 105 bits (261), Expect = 2e-22
Identities = 62/225 (27%), Positives = 120/225 (53%), Gaps = 12/225 (5%)
Query: 138 GRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREK 197
G+A + + + +E E R K +R +ER +DR +K + +R+ R++
Sbjct: 43 GQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQ-RDR 101
Query: 198 DKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGK 257
+K++E+ + +R RE ER R K R R + ER+ +RG RDR ++ ++E ER+ + K
Sbjct: 102 EKERERQTDRERDRQREKERNRQKERER-ETEREGERG---RDRQTDGQRERERQRDAEK 157
Query: 258 EKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLS 317
E+ER DR+R+R ++ + ++R R KN + + +R++ +E+ ++ S E ++
Sbjct: 158 ERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERE-- 215
Query: 318 DGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAE 362
++++ ETE + T + KT + R K + E + S+ E
Sbjct: 216 ----RETETETERKRQTDRERDRQRKTEREREKQA-ERERASERE 255
Score = 104 bits (259), Expect = 3e-22
Identities = 75/285 (26%), Positives = 138/285 (48%), Gaps = 14/285 (4%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDR---KQKEELKEDRKPREKDKDK 201
R ++ D + RE + K E + D E ++R T R+R +++E+ +++R+ RE+ ++K
Sbjct: 139 RDRQTDGQRERERQRDAEKERERQTDRE-RQRQTERNRQKEREREKNRQERRERERQREK 197
Query: 202 EKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKER 261
E E+ RH E RER + R +K + +RERDR + ++E E+++E + ER
Sbjct: 198 ENKTED---RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASER 254
Query: 262 LRDRDRERDRDKGKDRDR-RRVKNGEHSWDLDREKNREHDK-PEKKSASSGEMSKKLSDG 319
+RD+ER+R++ +DRDR RR K E D R++ E D+ E+K E ++
Sbjct: 255 ETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERN 314
Query: 320 TFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETP 379
++ + E E E R ++ + +R K + + + G G+ ++E
Sbjct: 315 RKRERERERERE-RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERER 373
Query: 380 EIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKT 424
E + S R R R ++++ + DR G +T
Sbjct: 374 ERERDRQSAREREERERDR----DRDRQKERERQTEKDRDGQRET 414
Score = 102 bits (253), Expect = 1e-21
Identities = 59/218 (27%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Query: 139 RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKD 198
R T R ++ K RE E + + +R ER R+R++ + DR+ +E++
Sbjct: 224 RKRQTDRERDRQRKTEREREKQAER---ERASERETERDKERERERDRDRDRDRRQKERE 280
Query: 199 KDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKE 258
+ ++ ++ R RE ER+R + R R ER+++R NR+R+R+ ER++E ER+ E ++
Sbjct: 281 RQTDRKRQRRTERDRETERKRERQRER---ERERER-NRKRERERERERERERQRETERD 336
Query: 259 KERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD------KPEKKSASSGEM 312
+E+ R+R R+R + ++R+R+ + G + +RE+ RE D + E++ +
Sbjct: 337 REKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDR 396
Query: 313 SKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSK 350
K+ T KD + ETE K ++ + R +
Sbjct: 397 QKERERQTEKDRDGQRETEKQREREKDRESERGRERGR 434
Score = 101 bits (251), Expect = 2e-21
Identities = 59/195 (30%), Positives = 106/195 (54%), Gaps = 15/195 (7%)
Query: 123 DAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEE-------SRVHKNTEDRGDAEIKE 175
D RR E+ + R T R +E + K R+ E +R + +R ++
Sbjct: 271 DRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQ 330
Query: 176 RSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRG 235
R T RDR+++ E K + R+ + D+E+ ++ G R+ ERER + R R D + ++R
Sbjct: 331 RETERDREKERERK---RKRQTEMDRERNRQTGREGRRQAERERERERER-DRQSARERE 386
Query: 236 NRERDRD----SERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDL 291
RERDRD ER+++TE+ +G +E E+ R+R+++R+ ++G++R R R K D
Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDR 446
Query: 292 DREKNREHDKPEKKS 306
+R+ +R+ + K+S
Sbjct: 447 ERQTDRQAGRQRKRS 461
Score = 100 bits (248), Expect = 5e-21
Identities = 79/349 (22%), Positives = 155/349 (44%), Gaps = 13/349 (3%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
++ K R T R ++ + R + + TE G+ ++R T R ++E ++
Sbjct: 98 QRDREKERERQTDRERDRQREKERNRQKERERETEREGERG-RDRQTDGQR-ERERQRDA 155
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNR------ERDRDSER 245
K RE+ D+E+ ++ NR +E ERE+ + R + ERQ+++ N+ ER R+ ER
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERR-ERERQREKENKTEDRHSERGRERER 214
Query: 246 KKETERKSEGGKEKERLRDRDR--ERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPE 303
++ETE ++E ++ +R RDR R ER+R+K +R+R + E + +RE++R+ D+
Sbjct: 215 ERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR 274
Query: 304 KKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEG 363
++ + +K T +D + E + E R + + KR + E + E
Sbjct: 275 RQKERERQTDRKRQRRTERDRETERKRE-RQRERERERERNRKRERERERERERERQRET 333
Query: 364 DAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGK 423
+ + + + E+ E + R R + R R + +D A + + +
Sbjct: 334 ERDREKERERKRKRQTEMDRERNRQTGREGRRQAERER-ERERERDRQSAREREERERDR 392
Query: 424 TVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHG 472
++ + D Q E + + E E E E++ G
Sbjct: 393 DRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKG 441
Score = 97.4 bits (241), Expect = 3e-20
Identities = 90/382 (23%), Positives = 162/382 (42%), Gaps = 25/382 (6%)
Query: 135 EVKGRASLTSRSQELDNKNVREEESRVHKNTE-----DRGDAEIKERSTSRDRKQKEELK 189
E + R +E D K R E H+ + R + +ER T R+R ++ E K
Sbjct: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQRE-K 119
Query: 190 EDRKPREKDKDKEKAKENGGNRHREGERERAKAR-ARPDNERQKDRGNRERDRDSERKKE 248
E + +E++++ E+ E G +R +G+RER + R A + ERQ D RER R +ER ++
Sbjct: 120 ERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTD---RERQRQTERNRQ 176
Query: 249 TERKSEGGKEKERLRDRDRER-----DRDKGKDRDRRRVKNGEHSWDLDREKNREHD--- 300
ER+ E +++ R R+R RE+ DR + R+R R + E + R+ +RE D
Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQR 236
Query: 301 KPEKKSASSGEMSKKLSDGTFKDSKAETETEIS---TRASKSLTTKTSKRRSKNSVEGDS 357
K E++ E + T +D + E E + R K +T ++R + + E D
Sbjct: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT-ERDR 295
Query: 358 TSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMD 417
++ + + + + E E E R R KR+ E +
Sbjct: 296 ETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRER 355
Query: 418 RSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKK 477
+G+ + E D Q E + + E+++ G ++
Sbjct: 356 NRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDG---QR 412
Query: 478 ILETKKDYEKLQQSPKPGEKER 499
E +++ EK ++S + E+ R
Sbjct: 413 ETEKQREREKDRESERGRERGR 434
Score = 95.1 bits (235), Expect = 2e-19
Identities = 76/306 (24%), Positives = 141/306 (46%), Gaps = 35/306 (11%)
Query: 139 RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR---KPR 195
R R + + + R++E ++ + D KER DRK++ + DR + R
Sbjct: 242 REKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKR 301
Query: 196 EKDKDKEKAKENGGNRHREGERERAKARARP---DNERQKDRGNR-----ERDRDSERKK 247
E+ +++E+ +E R RE ERER + R R D E++++R + +R+R+ + +
Sbjct: 302 ERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR 361
Query: 248 ETERKSEGGKEKERLRDR-------DRERDRDKG--KDRDRRRVKNGEHSWDLDREKNRE 298
E R++E +E+ER RDR +RERDRD+ K+R+R+ K+ + + ++++ RE
Sbjct: 362 EGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRERE 421
Query: 299 HDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNS--VEGD 356
D+ ++ G +K G +D + +T+ + + +S R+ S V+ D
Sbjct: 422 KDRESERGRERGREREK-QKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSD 480
Query: 357 STSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQM 416
G +PE P S+ R P A+ + RV + E
Sbjct: 481 PNRPTRG---------IRWKSSPEDPKAAST---RFPWGRPAKASRGRVAGRRRWEPRLG 528
Query: 417 DRSGSG 422
++ G G
Sbjct: 529 EKRGQG 534
Score = 93.6 bits (231), Expect = 5e-19
Identities = 61/229 (26%), Positives = 117/229 (51%), Gaps = 14/229 (6%)
Query: 137 KGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPRE 196
+ R R +E + R + +DR + R RDR+++ E + D RE
Sbjct: 56 RNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTD---RE 112
Query: 197 KDKDKEKAKENGGNRHREGERERAKARAR-PDNERQKDRGNRERDRDSERKKETERKSEG 255
+D+ +EK + R RE ERE + R R D +R+++ R+RD + ER+++T+R+ +
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERE---RQRDAEKERERQTDRERQR 169
Query: 256 GKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKK 315
E+ R ++R+RE++R + ++R+R+R K + + D E+ RE E++ + E +K
Sbjct: 170 QTERNRQKEREREKNRQERRERERQREKENK-TEDRHSERGRER---ERERETETETERK 225
Query: 316 LSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGD 364
+D + +TE E +A + + S+R ++ E + D + D
Sbjct: 226 RQTDRERDRQRKTEREREKQAERE---RASERETERDKERERERDRDRD 271
Score = 82.8 bits (203), Expect = 9e-16
Identities = 81/350 (23%), Positives = 158/350 (45%), Gaps = 29/350 (8%)
Query: 170 DAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNE 229
D + +ER+ ++R+++ E ++ RE D+ +E+ +E +RHR+ +R R E
Sbjct: 50 DGDDRERNRQKERERRREKRQTE--RETDRKRERRREK--DRHRKRDRHR---------E 96
Query: 230 RQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDR--DKGKDRDRRRVKNGEH 287
RQ+DR +ER+R ++R+++ +R+ KE+ R ++R+RE +R ++G+DR + E
Sbjct: 97 RQRDR-EKERERQTDRERDRQRE----KERNRQKERERETEREGERGRDRQTDGQRERER 151
Query: 288 SWDLDREKNREHDK-----PEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTT 342
D ++E+ R+ D+ E+ E K + ++ + E E + R S+
Sbjct: 152 QRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRE 211
Query: 343 KTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAP 402
+ +R ++ E +D E D + + E E +E + R R
Sbjct: 212 RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE-RDKERERERDRDR 270
Query: 403 PRVKRQDSMEALQMDRSGSGKTVSNVITE-SHNSDNEEDDQFVVEAAPQLSEMSEIEMVT 461
R +RQ E Q DR +T + TE E + + + E E
Sbjct: 271 DRDRRQKERER-QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER 329
Query: 462 AVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKD 511
E E + + K+ +T+ D E+ +Q+ + G ++ E ++E+D
Sbjct: 330 QRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER-ERERERERD 378
Score = 78.2 bits (191), Expect = 2e-14
Identities = 64/329 (19%), Positives = 138/329 (41%), Gaps = 18/329 (5%)
Query: 174 KERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKD 233
+ R S++ ++ L + K + D D+E+ NR +E ER R K + + +R+++
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGD-DRER------NRQKERERRREKRQTERETDRKRE 80
Query: 234 RG---NRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWD 290
R +R R RD R+++ +R+ E ++ +R RDR RE++R++ K+R+R + GE D
Sbjct: 81 RRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD 140
Query: 291 LDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSK 350
+ RE ++ + K+ T ++ + +TE + + + R +
Sbjct: 141 RQTDGQRERERQR-------DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER 193
Query: 351 NSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDS 410
+ + T D + G + + E E + R + R +R
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Query: 411 MEALQMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEK 470
E + D+ + + + + E + + +E + E E E +
Sbjct: 254 RET-ERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERE 312
Query: 471 HGGLVKKILETKKDYEKLQQSPKPGEKER 499
++ E +++ E+ +++ + EKER
Sbjct: 313 RNRKRERERERERERERQRETERDREKER 341
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 105 bits (261), Expect = 2e-22
Identities = 87/369 (23%), Positives = 166/369 (44%), Gaps = 26/369 (7%)
Query: 140 ASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEEL--KEDRKPREK 197
+S R E D ++ RE + R +G + ER R+ ++ + + + D + RE+
Sbjct: 620 SSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARER 679
Query: 198 DKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGK 257
D+++E+ +E R RE +RER K R + ER ++R RER+++ +R+++ +R + +
Sbjct: 680 DRERERDRERERERERERDREREKEREL-ERERARER-EREREKERDRERDRDRDHDRER 737
Query: 258 EKERLRDRDRERDRDK-GKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKL 316
E+ER RDR++ER+R++ ++R+R R + E + +RE+ RE DK ++ + K
Sbjct: 738 ERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKG- 796
Query: 317 SDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVP 376
+D + E EI R ++ +R+SK EG P K
Sbjct: 797 -----RDDRREKREEI--REDRNPRDGHDERKSKKRYRN------EGSPSPRQSPKRRRE 843
Query: 377 ETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSD 436
+P+ S + + ++ P+ R S L DR G K +S
Sbjct: 844 HSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSR 903
Query: 437 NEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILET-------KKDYEKLQ 489
E+ + + + + + E++ + + ++ G + ET K K+Q
Sbjct: 904 RYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQ 963
Query: 490 QSPKPGEKE 498
+ P +KE
Sbjct: 964 KKPIKKKKE 972
Score = 87.0 bits (214), Expect = 5e-17
Identities = 98/392 (25%), Positives = 169/392 (43%), Gaps = 67/392 (17%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTE-DRGDAEIKERSTSRDRKQKEELKE 190
E+ + R R +E + + R+ E + E +R +ER RDR++ +
Sbjct: 674 ERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDH 733
Query: 191 DR---KPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKK 247
DR + RE+D++KE RE ERE ER+++R RER+R+ ER++
Sbjct: 734 DRERERERERDREKE----------RERERE----------ERERER-ERERERERERER 772
Query: 248 ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSA 307
E ER E KE+ER RD + DK K RD RR K E D + + K +K+
Sbjct: 773 ERERARERDKERERQRDWE-----DKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYR 827
Query: 308 SSGEMSKKLSDGTFK----DSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEG 363
+ G S + S + DS A + + L+ + S++ T D +G
Sbjct: 828 NEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQG 887
Query: 364 -----DAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDR 418
D P ++ S E E+ ++SS K+++ E L+ R
Sbjct: 888 RWKEEDRKPERKESSRRYEEQELKEKVSS----------------VDKQREQTEILESSR 931
Query: 419 SGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKI 478
++I + D E D+ A + + ++I+ + +E++ G+ +
Sbjct: 932 ----MRAQDIIGHHQSEDRETSDR----AHDENKKKAKIQKKPIKKKKEDDV--GIERGN 981
Query: 479 LETKKDYEKLQQSPKPGEKERSLFESAWKKEK 510
+ET + ++ SPK G+K++S+ E KK K
Sbjct: 982 IETTSEDGQV-FSPKKGQKKKSI-EKKRKKSK 1011
Score = 68.6 bits (166), Expect = 2e-11
Identities = 56/238 (23%), Positives = 114/238 (47%), Gaps = 24/238 (10%)
Query: 162 HKNTEDRGDAEIKERSTSRDRKQKE--ELKEDRKPREKDKDKEKAKENGGNRHREGERER 219
H++ +D+ + S SRDR++ + E+ +RK R D+ K + R+ R
Sbjct: 1215 HRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRI-DQLKRGEPSRSTSSDRQDSRSH 1273
Query: 220 AKARARPDNERQ----------------KDRGNRERDRDSERKKETERKSEGGKEKE--R 261
+ R+ P+++RQ +DR +R+R+ ER+ +R+ + +K+ R
Sbjct: 1274 SSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPR 1333
Query: 262 LRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTF 321
RDRDR R+R++ ++RD+RR + E + R+ D+ ++ S ++
Sbjct: 1334 NRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAK 1393
Query: 322 KDSKAETETEISTRASKSLTTKTSKRRSKNSVEG--DSTSDAEGDAGPAGQDKSEVPE 377
+ + E + E ++R S +L K + SV+G ++ ++ AG D+S++ +
Sbjct: 1394 LEGEHERDLESTSRDSLAL-DKERMDKDLGSVQGFEETNKSERTESLEAGDDESKLDD 1450
Score = 59.7 bits (143), Expect = 8e-09
Identities = 73/376 (19%), Positives = 141/376 (37%), Gaps = 21/376 (5%)
Query: 150 DNKNVREEESRVHKNTED-RGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENG 208
D++ + R H+ ED RG +R +D +++ E ++D+ +D + ++
Sbjct: 402 DHERTSQSHDRRHERREDTRG-----KRDREKDSREEREYEQDQSSSRDHRDDREPRDGR 456
Query: 209 GNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRE 268
R R+R + R D ++ + RD R R + + RD
Sbjct: 457 DRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTH 516
Query: 269 RDRDKGKDRDRRRVKN---GEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSK 325
R D + R +N E S R ++R + E ++ G ++ + K S+
Sbjct: 517 RKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSR 576
Query: 326 AETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNEL 385
++I + +S S + + RS S E D P ++ + ++
Sbjct: 577 GSRGSQIDSHSSNSNYHDSWETRS---------SYPERDRYPERDNRDQARDS-SFERRH 626
Query: 386 SSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNEEDDQFVV 445
RR R RP+ P ++ Q + L+ D + V V E D +
Sbjct: 627 GERDRRDNRERDQRPSSP-IRHQGRNDELERDERREERRVDRVDDRRDERARERDRERER 685
Query: 446 EAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKERSLFESA 505
+ + E + E E E + ++ E ++D E+ + E+ER E
Sbjct: 686 DRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERER-ERD 744
Query: 506 WKKEKDIVSKEIEKLR 521
+KE++ +E E+ R
Sbjct: 745 REKEREREREERERER 760
Score = 59.7 bits (143), Expect = 8e-09
Identities = 58/193 (30%), Positives = 90/193 (46%), Gaps = 20/193 (10%)
Query: 144 SRSQELDNKNVREEESRVHKNTEDR------GDAEIKERSTSRDR----KQKEELKEDRK 193
SRS D ++ R SR DR G + ++R RDR +++E + D +
Sbjct: 1260 SRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTR 1319
Query: 194 PRE--KDKDKEKAKENGGNRHREGERERAKARARP-DNERQK---DRGNRERDRDSERKK 247
RE +D DK+ + +R RE ERER + + R D ER++ D R+RDRD +R
Sbjct: 1320 QREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTF 1379
Query: 248 ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKN-REHDKPEK-K 305
E+ + E K E + + ERD + RD + DL + E +K E+ +
Sbjct: 1380 ESS-QIESVKRCEAKLEGEHERDLE-STSRDSLALDKERMDKDLGSVQGFEETNKSERTE 1437
Query: 306 SASSGEMSKKLSD 318
S +G+ KL D
Sbjct: 1438 SLEAGDDESKLDD 1450
Score = 58.5 bits (140), Expect = 2e-08
Identities = 75/371 (20%), Positives = 151/371 (40%), Gaps = 37/371 (9%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKA 204
R +E D++ RE E + + R D E ++ RDR+ + ++ R+ R+ ++
Sbjct: 424 RDREKDSREEREYEQDQSSSRDHRDDREPRD---GRDRRDARDTRDRRELRDSRDMRDSR 480
Query: 205 KENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRD 264
+ +R + R+ +R+ D +DR RD+ RK++T + + LR+
Sbjct: 481 EMRDYSRDTKESRDPRDSRSTRDAHDYRDR----EGRDTHRKEDTYPEESRSYGRNHLRE 536
Query: 265 R-DRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASS--GEMSKKLSDGTF 321
R R++ ++ R ++N + R + R + PEK S S ++ S+ +
Sbjct: 537 ESSRTEIRNESRNESRSEIRNDR----MGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNY 592
Query: 322 KDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEI 381
DS TR+S + +R +++ S G+ +D+ + E +
Sbjct: 593 HDS-------WETRSSYPERDRYPERDNRDQARDSSFERRHGE-----RDRRDNRERDQR 640
Query: 382 PNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTV-SNVITESHNSDNEED 440
P SS IR R ++R + E ++DR + + D E +
Sbjct: 641 P---SSPIRHQGR-------NDELERDERREERRVDRVDDRRDERARERDRERERDRERE 690
Query: 441 DQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKERS 500
+ E + + E+E A E E E + ++ + D E+ ++ + EKER
Sbjct: 691 RERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERE 750
Query: 501 LFESAWKKEKD 511
++E++
Sbjct: 751 REREERERERE 761
Score = 56.6 bits (135), Expect = 7e-08
Identities = 73/335 (21%), Positives = 123/335 (36%), Gaps = 75/335 (22%)
Query: 118 KLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERS 177
+L + A R EK + R +E + + R+ E + E+R +ER
Sbjct: 706 ELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERE 765
Query: 178 TSRD-------------------------------RKQKEELKEDRKPREKDKDKEKAKE 206
R+ R+++EE++EDR PR+ D+ K+K+
Sbjct: 766 RERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRD-GHDERKSKK 824
Query: 207 NGGNRHREGERERAKAR--------------------------ARPDNERQ-------KD 233
N R+ K R RP R +D
Sbjct: 825 RYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTED 884
Query: 234 RGNR--ERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKN--GEHSW 289
R R E DR ER KE+ R+ E + KE++ D++R++ + + R R ++ G H
Sbjct: 885 RQGRWKEEDRKPER-KESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQS 943
Query: 290 DLDREKNREHDKPEKKSASSGEMSKKLSD---GTFKDSKAETETEISTRASKSLTTKTSK 346
+ +R HD+ +KK+ + KK + G + + T + + K K S
Sbjct: 944 EDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSI 1003
Query: 347 RRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEI 381
+ + +GD SD + K P TP I
Sbjct: 1004 EKKRKKSKGD--SDISDEEAAQQSKKKRGPRTPPI 1036
Score = 54.3 bits (129), Expect = 3e-07
Identities = 50/244 (20%), Positives = 93/244 (38%), Gaps = 27/244 (11%)
Query: 162 HKNTEDRGDAEIKERSTSRDRKQKEE----------LKEDRKPREKDKDKEKAKENGGNR 211
H ++ + + I+ S S RK+ L+ P ++ R
Sbjct: 331 HHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPR 390
Query: 212 HREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDR 271
HR RE+ + ++ R R D +R +E + + E E+++ RD DR
Sbjct: 391 HRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDR 450
Query: 272 DKGKDRDRRRVKNGEHSWDL-------DREKNREHDKPEKKSASSGEMSKKLSDGTFKD- 323
+ RDRR ++ +L D + R++ + K+S + ++D
Sbjct: 451 EPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDR 510
Query: 324 ------SKAETETEISTRASKS-LTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVP 376
K +T E S ++ L ++S+ +N +S S+ D G+ + VP
Sbjct: 511 EGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDR--MGRSRGRVP 568
Query: 377 ETPE 380
E PE
Sbjct: 569 ELPE 572
Score = 45.4 bits (106), Expect = 2e-04
Identities = 69/326 (21%), Positives = 126/326 (38%), Gaps = 45/326 (13%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKE-ELKEDRKPREKD---KD 200
R +E D K R+E SR ++ + E+KE+ +S D+++++ E+ E + R +D
Sbjct: 888 RWKEEDRKPERKESSRRYE------EQELKEKVSSVDKQREQTEILESSRMRAQDIIGHH 941
Query: 201 KEKAKENGGNRHREGERERAKARARPDNERQKD-----RGNRERDRDS---------ERK 246
+ + +E H E ++ +AK + +P ++++D RGN E + ++K
Sbjct: 942 QSEDRETSDRAHDENKK-KAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKK 1000
Query: 247 KETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKS 306
K E+K + K + D + + K + + E ++ KN + +KK
Sbjct: 1001 KSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKE 1060
Query: 307 ASSGEMSKKLSDGTFKDSKAETETEISTRAS---------KSLTTKTSKRRSKNSVEGDS 357
++ SD D TE E + A+ SL + + +
Sbjct: 1061 DTA---FSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPA 1117
Query: 358 TSDAEGDAGPAGQDKSEVP-ETPEIPNELSSNI-------RRIPRPGSARPAPPRVKRQD 409
T A A S + T P ++N R+ R + P V +D
Sbjct: 1118 TLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIED 1177
Query: 410 SMEALQMDRSGSGKTVSNVITESHNS 435
+ MD+ S SN SH S
Sbjct: 1178 AQHRKPMDQKRSSSLGSNRSNRSHTS 1203
Score = 42.4 bits (98), Expect = 0.001
Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 29/216 (13%)
Query: 203 KAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262
+ K N R ER R R N+RQ D D+E +K +S KE
Sbjct: 66 RGKGYSSNYRRSPERPTGDLRERMKNKRQ--------DVDTEPQKRNTEESSSPVRKESS 117
Query: 263 RDRDRERD-----RDKGKDRDRRRVK---------NGEHSWDLDREKNREHDKPEKKSAS 308
R R RE++ +++ + + V+ NG+ ++D E + E K+
Sbjct: 118 RGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLE----MKRQKI 173
Query: 309 SGEMSKKLSDGTFKDSKAETETEISTRASKS-LTTKTSKRRSKNSVEGDSTSDAEGDAGP 367
E+ K + K + + E+S +S L+ S R+S S + S + +
Sbjct: 174 QRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPK--RKSSPKSSSAS 231
Query: 368 AGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPP 403
K+ +P + + +S + + G P+PP
Sbjct: 232 KKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPP 267
Score = 39.3 bits (90), Expect = 0.011
Identities = 48/252 (19%), Positives = 93/252 (36%), Gaps = 59/252 (23%)
Query: 159 SRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERE 218
+RV K E + D+K+ L +R R + ++ N + HR G+ +
Sbjct: 1163 TRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSND-SAHRSGDDQ 1221
Query: 219 RAKARARPDNERQKDRGNRERDR--------------DSERKKETERKSEGGKEKER--- 261
+ R G+R+R++ D ++ E R + ++ R
Sbjct: 1222 SGRKRVLHS-------GSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHS 1274
Query: 262 --------------------LRDRDRERDR-DKGKDRDRRRVKNGEHSWDLDREK----N 296
RDR +ERDR + ++R+R R + WD D +K N
Sbjct: 1275 SRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRN 1334
Query: 297 REHDK---------PEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKR 347
R+ D+ +K+ E + +SD +D + + + +S+ +K
Sbjct: 1335 RDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKL 1394
Query: 348 RSKNSVEGDSTS 359
++ + +STS
Sbjct: 1395 EGEHERDLESTS 1406
Score = 36.2 bits (82), Expect = 0.093
Identities = 57/306 (18%), Positives = 115/306 (37%), Gaps = 27/306 (8%)
Query: 127 RVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRK--- 183
R + G KG +S RS E ++RE ++ + E S+S RK
Sbjct: 58 RFVHGPSPRGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESS 117
Query: 184 -----QKEELK--EDRKPREKDKDKE----KAKENGGNRHREGERERAKARARPDNERQ- 231
+KE++K ++R P ++++ E + + G+ + + E + R +R+
Sbjct: 118 RGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQREL 177
Query: 232 --KDRGNRERDRDSERKKET------ERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVK 283
++ N E+ + KKE + S ++ + R+ + R
Sbjct: 178 MKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKT 237
Query: 284 NGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTK 343
+ S LD+++N + ++ +KK + + + K + + ++ R + T+
Sbjct: 238 SAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEK--TR 295
Query: 344 TSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNI--RRIPRPGSARPA 401
K R ++ D PAGQ S + + S + R P P R
Sbjct: 296 DGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTP 355
Query: 402 PPRVKR 407
P +R
Sbjct: 356 SPSYQR 361
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 103 bits (257), Expect = 5e-22
Identities = 57/188 (30%), Positives = 105/188 (55%), Gaps = 7/188 (3%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-KPREKDKDKEK 203
R ++ + +E E + E E + R RDR ++ + + DR K RE+ K++++
Sbjct: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64
Query: 204 AKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSE----GGKEK 259
++ RE ER+R + R R + +RQ DR R++DRD ERK+ET+R E GG+E+
Sbjct: 65 QRQRERETERETERQRERQRQR-ERKRQTDR-ERDKDRDRERKRETDRNRERNRKGGRER 122
Query: 260 ERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDG 319
++ +R+R+R+R++ + R+R R + E + DRE+ R ++ E+K E K+ +
Sbjct: 123 DKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEK 182
Query: 320 TFKDSKAE 327
++ + E
Sbjct: 183 KKEEKRRE 190
Score = 94.0 bits (232), Expect = 4e-19
Identities = 57/187 (30%), Positives = 98/187 (52%), Gaps = 14/187 (7%)
Query: 157 EESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGE 216
E R K DRG +ER R+R+ + E + + R++ +++++ + R R+ E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 217 RERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLR--DRDRERDRDKG 274
R+R + R R + ER+ +R RER R ERK++T+R+ + +++ER R DR+RER+R G
Sbjct: 62 RDRQRQRER-ETERETER-QRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 275 ----------KDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDS 324
+DR+R R + E RE+ RE D+ ++ A E K+ K+
Sbjct: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
Query: 325 KAETETE 331
K + + E
Sbjct: 180 KEKKKEE 186
Score = 85.1 bits (209), Expect = 2e-16
Identities = 54/177 (30%), Positives = 91/177 (51%), Gaps = 15/177 (8%)
Query: 187 ELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERK 246
E + +RK RE D+ KE +E R RE + ER + D R++DR +R+++ ER+
Sbjct: 2 ERQRERK-RETDRGKETERERDRQRERENQTERENRHRQRDRHRERDR-QTDREKERERQ 59
Query: 247 K----------ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKN 296
K ETER++E +E++R R+R R+ DR++ KDRDR R + + + + +R+
Sbjct: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 297 REHDKP---EKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSK 350
RE DK E+ + ++ ++ K ET+ E A + K K+ K
Sbjct: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERK 176
Score = 83.6 bits (205), Expect = 5e-16
Identities = 51/188 (27%), Positives = 102/188 (54%), Gaps = 15/188 (7%)
Query: 137 KGRASLTSRSQELDNKNVREEESRV-----HKNTEDRGDAEI-KERSTSRDRKQKEELKE 190
+G+ + R ++ + +N E E+R H+ + + D E +ER RDR+++ E +
Sbjct: 13 RGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERET 72
Query: 191 DRKP-REKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD------RDS 243
+R+ R++++ +++ ++ +R R+ +R+R + R N + +G RERD RD
Sbjct: 73 ERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDR 132
Query: 244 ERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPE 303
ER+++ +R+ E +++ER R+ DRER R +R+ R+ + + +EK +E + E
Sbjct: 133 ERERQRQRERERQRQRERKRETDRERQR--WAEREERKKERKKERKKERKEKKKEEKRRE 190
Query: 304 KKSASSGE 311
K GE
Sbjct: 191 DKKRKWGE 198
Score = 79.7 bits (195), Expect = 7e-15
Identities = 52/176 (29%), Positives = 93/176 (52%), Gaps = 18/176 (10%)
Query: 135 EVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIK-ERSTSRDR---KQKEELKE 190
E + R R +E D + RE+E K + + E + ER T R R +Q+E ++
Sbjct: 32 ERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQ 91
Query: 191 DRKPREKDKDKEKAKENGGNR--HREGERERAKARARPDNERQKDRGNRERDRDSERKKE 248
+ R+KD+D+E+ +E NR +R+G RER K + RERDR+ ER+++
Sbjct: 92 TDRERDKDRDRERKRETDRNRERNRKGGRERDK------------QTERERDRERERQRQ 139
Query: 249 TERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEK 304
ER+ + +E++R DR+R+R ++ + + R+ + + + +E+ R DK K
Sbjct: 140 RERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRK 195
Score = 68.9 bits (167), Expect = 1e-11
Identities = 47/147 (31%), Positives = 77/147 (52%), Gaps = 16/147 (10%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
E+ K R R +E + + R+ E + + + + D +ER RDR++K E +
Sbjct: 55 ERERQKERDRQRQRERETERETERQRERQRQRERKRQTD---RERDKDRDRERKRETDRN 111
Query: 192 RKP-----REKDKDKEKAKENGGNRHREGERERAKARAR---PDNERQK--DRGNRERDR 241
R+ RE+DK E+ ++ R R+ ERER + R R D ERQ+ +R R+++R
Sbjct: 112 RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKER 171
Query: 242 DSERKKETERKSEGGKEKERLRDRDRE 268
ERKKE + K KE++R D+ R+
Sbjct: 172 KKERKKERKEKK---KEEKRREDKKRK 195
Score = 52.4 bits (124), Expect = 1e-06
Identities = 28/126 (22%), Positives = 63/126 (50%), Gaps = 8/126 (6%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
E+ + R T R ++ D R+ E+ ++ +G E +++ T R+R ++ E
Sbjct: 81 ERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE-RDKQTERERDRERE---- 135
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
R++ +++E+ ++ R + ER+R R ER+K+R +++ E K+ ++
Sbjct: 136 ---RQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDK 192
Query: 252 KSEGGK 257
K + G+
Sbjct: 193 KRKWGE 198
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/104 (23%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
+K + R T R++E + K RE + + + DR ++R R R+++ + + D
Sbjct: 97 DKDRDRERKRETDRNRERNRKGGRERDKQTERE-RDRERERQRQRERERQRQRERKRETD 155
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRG 235
R+ + + +E+ KE R +E + ++ + + R D +R+ G
Sbjct: 156 RERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 199
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 101 bits (251), Expect = 2e-21
Identities = 63/201 (31%), Positives = 107/201 (53%), Gaps = 25/201 (12%)
Query: 143 TSRSQELDNKNVRE---EESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-KPREKD 198
T + ++ D K RE +E ++N + EI ER R++++ E + DR + RE+D
Sbjct: 88 TEKERDRDRKRDRERRRKEKETNRNRDREKQTEI-ERDREREKQKGRERERDRGRERERD 146
Query: 199 KDKEKAKENGGNRHREGERERAKARARP-DNERQKDRGNR-----------------ERD 240
+D+EK +E + R+G+RE R R + E+QK+R +R+
Sbjct: 147 RDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRE 206
Query: 241 RDSERKKETERKSEGGKEKERLRD--RDRERDRDKGKDRDRRRVKNGEHSWDLDREKNRE 298
RD +RK +TER+ E +E ER D R+R+RDRD+GK+RDR R + E + +E+ +E
Sbjct: 207 RDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKE 266
Query: 299 HDKPEKKSASSGEMSKKLSDG 319
+ +K+ + +K +G
Sbjct: 267 RKEKKKEEKRREDKKRKWGEG 287
Score = 100 bits (248), Expect = 5e-21
Identities = 61/227 (26%), Positives = 114/227 (50%), Gaps = 4/227 (1%)
Query: 134 GEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDA-EIKERSTSRDRKQKEELKEDR 192
G+ A R +E D + E+ R DR + KE + +RDR+++ E++ DR
Sbjct: 66 GQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDR 125
Query: 193 KPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERK 252
+ REK K +E+ ++ G R R+ +RE+ + R + + ER+RD ER+K+ ER+
Sbjct: 126 E-REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERE 184
Query: 253 SEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEM 312
+E ++++R RD ++ER+R ++RDR+R E + DRE RE D+ ++
Sbjct: 185 TE--RDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRG 242
Query: 313 SKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTS 359
++ + K+ + + + + K + +R K G+ S
Sbjct: 243 KERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGIS 289
Score = 92.0 bits (227), Expect = 1e-18
Identities = 59/193 (30%), Positives = 103/193 (53%), Gaps = 9/193 (4%)
Query: 123 DAVRRVLAGEKGEVKGRASLTS--RSQELDNKNVREEE-SRVHKNTEDRGDAEIKERSTS 179
D RR E + R T R +E + + RE E R + DR + +ER T
Sbjct: 99 DRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTE 158
Query: 180 RDRKQKEELKEDR-KPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRE 238
+DR + E + +R + RE++K KE+ E +R R+ E+ER + R + ++K + R+
Sbjct: 159 KDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQ 218
Query: 239 RDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNRE 298
R+ D E ++ET+R+ +E++R RDR +ERDR++ + +R++ + E + +EK +E
Sbjct: 219 RETDREGERETDRR----RERQRDRDRGKERDRERDRKEERKKERKKERKKE-RKEKKKE 273
Query: 299 HDKPEKKSASSGE 311
+ E K GE
Sbjct: 274 EKRREDKKRKWGE 286
Score = 82.8 bits (203), Expect = 9e-16
Identities = 49/179 (27%), Positives = 90/179 (50%), Gaps = 8/179 (4%)
Query: 188 LKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKK 247
L PR + +G +R RE +R R K D +R++DR R +++++ R +
Sbjct: 54 LGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNR 113
Query: 248 ETERKSEGGKEKERLRDRDRERDRDKG--KDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
+ E+++E +++ER + + RER+RD+G ++RDR R K E + DR+ RE + ++
Sbjct: 114 DREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERER 173
Query: 306 SASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGD 364
E K+ T +D + +TE + + T + R+ K E +D EG+
Sbjct: 174 DR---EREKQKERETERDRDRQRDTE---KERERQTDRERDRQRKTQTERQRETDREGE 226
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 98.2 bits (243), Expect = 2e-20
Identities = 61/187 (32%), Positives = 102/187 (54%), Gaps = 23/187 (12%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-----KPREKDK 199
R +E D + R +ES+ +R +ER+ RDR ++ E + DR + RE+D+
Sbjct: 23 RRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDR 82
Query: 200 DK------EKAKENGGNRHREGERERAKARARP-----DNERQKDR-----GNRERDRDS 243
D+ E+ KE +RH E +RER K + R D ER+K + +R+ D
Sbjct: 83 DRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDR 142
Query: 244 ERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRR-VKNGEHSWDLDREKNREHDKP 302
ER+++ ER+ E G+E+ + DR RER+R++ ++R+R+R K E D++RE+ RE D+
Sbjct: 143 ERERQAERERETGRER-KTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRK 201
Query: 303 EKKSASS 309
+ S
Sbjct: 202 RDRQRES 208
Score = 88.6 bits (218), Expect = 2e-17
Identities = 61/216 (28%), Positives = 102/216 (47%), Gaps = 22/216 (10%)
Query: 155 REEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHRE 214
+ E H TE + R T R+R + +E K + + E+D+ +++ + NR R+
Sbjct: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRER----NRERD 59
Query: 215 GERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKG 274
+RER K R + ERQ RER+RD +R++ETER+ + +E +R + DRER + K
Sbjct: 60 RDREREKQTDR-EGERQ-----RERERDRDRQRETERERDKERETDRHTETDRERQKQKE 113
Query: 275 ------KDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAET 328
+DR+R + K DRE +RE ++ ++ +G K +D E
Sbjct: 114 REMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKT------EDRHRER 167
Query: 329 ETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGD 364
E E + TK +R + E +D + D
Sbjct: 168 ERERKRERERKRETKERERHTDMERERQRETDRKRD 203
Score = 84.7 bits (208), Expect = 2e-16
Identities = 58/159 (36%), Positives = 85/159 (53%), Gaps = 8/159 (5%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIK-ERSTSRDR---KQKEE 187
E+ + R T R E + R+ + + + TE D E + +R T DR KQKE
Sbjct: 57 ERDRDREREKQTDREGERQRERERDRDRQ--RETERERDKERETDRHTETDRERQKQKER 114
Query: 188 LKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKK 247
E + RE++K KE +E +R + ERER R R + R++ +R R+R+ ERK+
Sbjct: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERER-ETGRERKTEDRHRERERERKR 173
Query: 248 ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGE 286
E ERK E KE+ER D +RER R+ + RDR+R E
Sbjct: 174 ERERKRET-KERERHTDMERERQRETDRKRDRQRESERE 211
Score = 82.8 bits (203), Expect = 9e-16
Identities = 57/165 (34%), Positives = 88/165 (53%), Gaps = 9/165 (5%)
Query: 117 NKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTE-DRGDAEIKE 175
N+ D R +GE + R R ++ + + R++E ++TE DR + KE
Sbjct: 55 NRERDRDREREKQTDREGE-RQRERERDRDRQRETERERDKERETDRHTETDRERQKQKE 113
Query: 176 RSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRG 235
R R R ++ E K+ RE+ D+E +E R R+ ERER R R +R ++R
Sbjct: 114 REMERVRDRERE-KQKEMGRERQTDRETDRE----RERQAERERETGRERKTEDRHRER- 167
Query: 236 NRERDRDSERKKET-ERKSEGGKEKERLRDRDRERDRDKGKDRDR 279
RER R+ ERK+ET ER+ E+ER R+ DR+RDR + +R+R
Sbjct: 168 ERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERER 212
Score = 81.3 bits (199), Expect = 3e-15
Identities = 60/205 (29%), Positives = 106/205 (51%), Gaps = 27/205 (13%)
Query: 170 DAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGG-NRHREGERERAKARARPDN 228
+++ + R T + + + +E R RE D+++++AKE+ +RH E +R+R D
Sbjct: 2 ESKTEGRHTHTETETMDRQRERR--RETDRERDRAKESKTEDRHSERDRQR-------DR 52
Query: 229 ERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDR--------DRERDRDKGKDRDRR 280
ER NRERDRD ER+K+T+R+ E +E+ER RDR D+ER+ D+ + DR
Sbjct: 53 ER-----NRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRE 107
Query: 281 RVKNGEHSWDLDREKNREHDKP---EKKSASSGEMSKKLSDGTFKDSKAETETEISTRAS 337
R K E + R++ RE K E+++ + ++ +++ E +TE R
Sbjct: 108 RQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHR-E 166
Query: 338 KSLTTKTSKRRSKNSVEGDSTSDAE 362
+ K + R + + E + +D E
Sbjct: 167 RERERKRERERKRETKERERHTDME 191
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 94.0 bits (232), Expect = 4e-19
Identities = 56/176 (31%), Positives = 97/176 (55%), Gaps = 16/176 (9%)
Query: 145 RSQELDNKNVRE---EESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDK 201
R +E K +E E+ R + DR +ER RDR +K E DR RE + ++
Sbjct: 64 RERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRD-RETETER 122
Query: 202 EKAKENGGNRHREGERERAKAR-----------ARPDNERQKDRGNRERDRDSERKKETE 250
++ +E +R RE +RER + R D +R+++ G ER RD ER+++ +
Sbjct: 123 QEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQ 182
Query: 251 RKSEGGKEKERLRDR-DRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
R++ +++ER R++ DRERDRD+ K+R++ R + E D D+E++RE + + +
Sbjct: 183 RETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDR 238
Score = 90.1 bits (222), Expect = 5e-18
Identities = 60/182 (32%), Positives = 101/182 (55%), Gaps = 8/182 (4%)
Query: 126 RRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQK 185
+R A E+ K R R ++ R+ + E GD ++R T +R+++
Sbjct: 69 QRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD---RDRETETERQEE 125
Query: 186 EELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSER 245
E + DRK REKD+++++ +E G ++ RE E E+ + R R E ++ R +RER+R +R
Sbjct: 126 RERQRDRK-REKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR-DRERERQKQR 183
Query: 246 KKETERKSEGGKEKE-RLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEK 304
+ +R E +EKE R RDRDR+++R+ KDR R R + + DRE+ RE D+ +
Sbjct: 184 ETRRDRDRERQREKEDRERDRDRQKERE--KDRYRERETGRDRDKERDRERQREKDRDRQ 241
Query: 305 KS 306
K+
Sbjct: 242 KA 243
Score = 87.8 bits (216), Expect = 3e-17
Identities = 61/183 (33%), Positives = 99/183 (54%), Gaps = 18/183 (9%)
Query: 133 KGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR 192
+ +++ R L R + +RE E + +R KER +DR+ +++ R
Sbjct: 36 RSQIEDRDVLILRGSRVAPAIIRERE---RQRERERQRKRAKERHREKDREIEKDRDRQR 92
Query: 193 K---PREKDKDKEKAKENGGNRHREGERERAKARARP-DNERQKDRGNR-------ERDR 241
K R++ +D+++ +E G+R RE E ER + R R D +R+KDR + ++DR
Sbjct: 93 KRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDR 152
Query: 242 DSERKKETERKSEGGKEKERLRDRDRER--DRDKGKDRDRRRVKNGE-HSWDLDREKNRE 298
+ E +K+ +R+ E G E ER RDR+RER R+ +DRDR R + E D DR+K RE
Sbjct: 153 EIETEKDRDREREMG-ETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKERE 211
Query: 299 HDK 301
D+
Sbjct: 212 KDR 214
Score = 79.7 bits (195), Expect = 7e-15
Identities = 55/166 (33%), Positives = 93/166 (56%), Gaps = 30/166 (18%)
Query: 171 AEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNER 230
A I+ER R+R+++ + ++R REKD++ EK ++ R R+ +RER + R D +R
Sbjct: 55 AIIRERERQRERERQRKRAKERH-REKDREIEKDRD----RQRKRDRERQRWR---DRDR 106
Query: 231 QKDR-GNRERDRDSERKKETERKSEGGKEKERLRDR----------------DRERDRDK 273
+++R G+R+R+ ++ER++E ER+ + +EK+R R R DR+R+R+
Sbjct: 107 KRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREM 166
Query: 274 G-----KDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSK 314
G +DR+R R K E D DRE+ RE + E+ E K
Sbjct: 167 GETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREK 212
Score = 76.6 bits (187), Expect = 6e-14
Identities = 50/180 (27%), Positives = 92/180 (51%), Gaps = 10/180 (5%)
Query: 188 LKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGN---RERDRDSE 244
++E + RE+++ +++AKE RHRE +RE K R D +R++DR R+RDR E
Sbjct: 57 IRERERQRERERQRKRAKE----RHREKDREIEKDR---DRQRKRDRERQRWRDRDRKRE 109
Query: 245 RKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEK 304
R + +R++E +++ER R RDR+R++D+ + R R + + + +++++RE + E
Sbjct: 110 RWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGET 169
Query: 305 KSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGD 364
+ E ++ T +D E + E R K ++ E D E D
Sbjct: 170 ERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERD 229
Score = 60.5 bits (145), Expect = 5e-09
Identities = 40/150 (26%), Positives = 76/150 (50%), Gaps = 12/150 (8%)
Query: 227 DNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRE--RDRDKGKDR--DRRRV 282
+ ERQ++R R+R R ER +E +R+ E ++++R RDR+R+ RDRD+ ++R DR R
Sbjct: 59 ERERQRER-ERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
Query: 283 KNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTT 342
E + +R+++R+ +K E ++ G KD + ETE + T
Sbjct: 118 TETERQEERERQRDRKREKDR-------ERQRQREIGIDKDREIETEKDRDREREMGETE 170
Query: 343 KTSKRRSKNSVEGDSTSDAEGDAGPAGQDK 372
+ R + + ++ D + + +D+
Sbjct: 171 RYRDRERERQKQRETRRDRDRERQREKEDR 200
Score = 34.3 bits (77), Expect = 0.35
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 123 DAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDR 182
D R + E+ + R R D R+ E + DR K+R R+
Sbjct: 161 DREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERET 220
Query: 183 KQKEELKEDR-KPREKDKDKEKA 204
+ + + DR + REKD+D++KA
Sbjct: 221 GRDRDKERDRERQREKDRDRQKA 243
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 93.2 bits (230), Expect = 6e-19
Identities = 59/188 (31%), Positives = 104/188 (55%), Gaps = 12/188 (6%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKA 204
R + K RE+E + + +++ + +ER R+RK+KE K+ ++ REK++ K K
Sbjct: 40 RREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKK 99
Query: 205 KENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRD 264
++ R + G RER K + R + ER+ ++ RER R RKK +R+ E +EKER +
Sbjct: 100 EKKKRERKQRGRRERKKKKERKERERE-NKQRRERKRKKRRKK--KRRKERKREKERGK- 155
Query: 265 RDRERDRDKGKDRDRRRVKN-GEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKD 323
R+R+R + K ++R+++R +N E + +R++ RE K KK + K KD
Sbjct: 156 RERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK-------KD 208
Query: 324 SKAETETE 331
K + +T+
Sbjct: 209 RKTDRQTD 216
Score = 90.5 bits (223), Expect = 4e-18
Identities = 59/204 (28%), Positives = 102/204 (50%), Gaps = 8/204 (3%)
Query: 111 IGKCCLNKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGD 170
I K C + S RR K E + +E + RE + ++R
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Query: 171 AEIKERSTSRDRKQKEELKEDRKPR------EKDKDKEKAKENGGNRHREGERERAKARA 224
+ R R +++KE+ K +RK R +K + KE+ +EN R R+ ++ R K R
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR- 143
Query: 225 RPDNERQKDRGNRERDRDSERKKETERKSE-GGKEKERLRDRDRERDRDKGKDRDRRRVK 283
R + +R+K+RG RER R +K+E E+K E KE+++ R+R R+R K + ++RR+ K
Sbjct: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
Query: 284 NGEHSWDLDREKNREHDKPEKKSA 307
+ DR+ + + +P ++SA
Sbjct: 204 ERKKDRKTDRQTDSQVFRPLRESA 227
Score = 85.5 bits (210), Expect = 1e-16
Identities = 52/194 (26%), Positives = 106/194 (54%), Gaps = 10/194 (5%)
Query: 143 TSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKE 202
T R E + E+ + + E + + KE+ + R++ +E + RK REK + +
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 203 KAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262
+ KE R R+ E+++ + + R ER+K + +ER+R++++++E +RK K +++
Sbjct: 90 REKE---RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK----KRRKKK 142
Query: 263 RDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSK--KLSDGT 320
R ++R+R++++GK R+R+R K + + RE+NR+ K E++ E K K
Sbjct: 143 RRKERKREKERGK-RERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
Query: 321 FKDSKAETETEIST 334
K+ K + +T+ T
Sbjct: 202 KKERKKDRKTDRQT 215
Score = 84.3 bits (207), Expect = 3e-16
Identities = 59/201 (29%), Positives = 107/201 (53%), Gaps = 12/201 (5%)
Query: 171 AEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGN-RHREGERERAKARARPDNE 229
+ I + T R+ ++K+E +E R+ R+++++KE+ +E G + + +RER K R R E
Sbjct: 23 SHISKPCTQRESERKKERRE-REKRKREREKERKRERGKKEKKKRKKRERGKERERKRKE 81
Query: 230 RQKDRGNRE----RDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNG 285
R+K R R R R E+KK ERK G +E+++ ++R +ER+R+ + R+R+R K
Sbjct: 82 REKQRKERREKERRKRKKEKKKR-ERKQRGRRERKKKKER-KERERENKQRRERKRKKRR 139
Query: 286 EHSWDLDREKNREHDKPE-KKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKT 344
+ +R++ +E K E K+ E +K + K+ K E E + K +
Sbjct: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE---RK 196
Query: 345 SKRRSKNSVEGDSTSDAEGDA 365
+RR K + D +D + D+
Sbjct: 197 KERRKKKERKKDRKTDRQTDS 217
Score = 42.4 bits (98), Expect = 0.001
Identities = 22/96 (22%), Positives = 47/96 (48%)
Query: 139 RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKD 198
R + + + K +E R K + + + K+R +R ++KE +++R+ R+K+
Sbjct: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
Query: 199 KDKEKAKENGGNRHREGERERAKARARPDNERQKDR 234
+ KE+ K+ + R+ +R+ RP E +R
Sbjct: 195 RKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 92.8 bits (229), Expect = 8e-19
Identities = 65/240 (27%), Positives = 120/240 (50%), Gaps = 15/240 (6%)
Query: 136 VKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPR 195
V+ R S + R ++ R SR H + E G + +R R+ K+++ L+ + K R
Sbjct: 255 VERRRSRSPRRSLSPRRSPRRSRSRSH-HREGHGSSSF-DRELERE-KERQRLEREAKER 311
Query: 196 EKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEG 255
EK++ + ++ + G R R RER ++R+R +DR RDRD ER+KE ER
Sbjct: 312 EKERRRSRSIDRGLERRRSRSRERHRSRSR-----SRDRKGDRRDRDREREKENER---- 362
Query: 256 GKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNRE--HDKPEKKSASSGEMS 313
G+ ++R D++R +R+K ++R R R K +++ +K++E D+ + +
Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKE 422
Query: 314 KKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKS 373
KK S ++ K + + S A K +++ ++ SK+ E S+ +G G+ S
Sbjct: 423 KKHSRSRSRERKHRSRSR-SRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDS 481
Score = 82.4 bits (202), Expect = 1e-15
Identities = 67/233 (28%), Positives = 103/233 (44%), Gaps = 31/233 (13%)
Query: 147 QELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKE 206
Q L+ + E+ R + DRG + RS SR+R + DRK +D+D+E+ KE
Sbjct: 302 QRLEREAKEREKERRRSRSIDRGLE--RRRSRSRERHRSRSRSRDRKGDRRDRDREREKE 359
Query: 207 NGGNRHREGERERAKARARPDNERQKDRG-NRERDRDSERKKETERKS------------ 253
N R R+ + ++ + NER+K+R +RER ++ + E E K
Sbjct: 360 NERGRRRDRDYDKERG-----NEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRD 414
Query: 254 ---EGGKEKERLRDRDRERDRDKGKDRDRRRVKN-GEHSWDLDREKNREHDKPEKKSASS 309
+ KEK+ R R RER K R R R +N G+ S +EK+ +H K+ S
Sbjct: 415 DKRDSKKEKKHSRSRSRER-----KHRSRSRSRNAGKRSRSRSKEKSSKHKNESKE--KS 467
Query: 310 GEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAE 362
+ S+ S G + + E S KS SK RS DS ++
Sbjct: 468 NKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSD 520
Score = 78.6 bits (192), Expect = 2e-14
Identities = 53/226 (23%), Positives = 106/226 (46%), Gaps = 10/226 (4%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
E+ + R SRS+ D K R + R + +RG ++R ++R + E KE
Sbjct: 326 ERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERG--RRRDRDYDKERGNERE-KER 382
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
+ RE+ K++ E +H+E + +R R R D K R R ERK +
Sbjct: 383 ERSRERSKEQRSRGEVEEKKHKEDKDDR---RHRDDKRDSKKEKKHSRSRSRERKHRSRS 439
Query: 252 KSEGGKEKERLRDRDR-ERDRDKGKDRDRRRVKNGE--HSWDLDREKNREHDKPEKKSAS 308
+S ++ R R +++ + +++ K++ +R ++G + +++ K REH ++KS
Sbjct: 440 RSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRK 499
Query: 309 SGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVE 354
++ DSK +++ R S+S+ ++ +++ KN E
Sbjct: 500 RSRSKERSHKRDHSDSKDQSDKH-DRRRSQSIEQESQEKQHKNKDE 544
Score = 73.6 bits (179), Expect = 5e-13
Identities = 72/311 (23%), Positives = 129/311 (41%), Gaps = 35/311 (11%)
Query: 170 DAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNE 229
D ++ R + R+ + R+ R + +E + +R E E+ER +
Sbjct: 252 DRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKER 311
Query: 230 RQKDRGNRERDRDSERKKETERKSEGGKEKERLRD---RDRERDRDKGKDRDRRRVKNGE 286
++ R +R DR ER++ R+ + + R R RDR+R+R+K +R RRR ++ +
Sbjct: 312 EKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYD 371
Query: 287 HSWDLDREKNREHDKP-EKKSASSGEMSKK-----LSDGTFKDSKAETETEISTRASKSL 340
+REK RE + K+ S GE+ +K D +D K +++ E S+S
Sbjct: 372 KERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSR 431
Query: 341 TTK-TSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSAR 399
K S+ RS+N AG + +S+ ++ + NE + R GS
Sbjct: 432 ERKHRSRSRSRN-------------AGKRSRSRSK-EKSSKHKNESKEKSNKRSRSGSQ- 476
Query: 400 PAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEM 459
R DS+E + K S + S ++ D + S+ +
Sbjct: 477 ------GRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDH----SDSKDQSDKHDRRR 526
Query: 460 VTAVELEEEEK 470
++E E +EK
Sbjct: 527 SQSIEQESQEK 537
Score = 65.5 bits (158), Expect = 1e-10
Identities = 59/251 (23%), Positives = 104/251 (41%), Gaps = 6/251 (2%)
Query: 173 IKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQK 232
I ++ +R RK K++ KE + E D+ E+ + R R ++R+R + ++
Sbjct: 229 IDQQIKTRPRKIKKDGKEGAE--EIDRHVERRRSRSPRRSLSPRRSPRRSRSR--SHHRE 284
Query: 233 DRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLD 292
G+ DR+ ER+KE +R KE+E+ R R R DR + R R R ++ S D
Sbjct: 285 GHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRD 344
Query: 293 RE-KNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKN 351
R+ R+ D+ +K G + D + ++ E E E S SK ++ K+
Sbjct: 345 RKGDRRDRDREREKENERGRRRDRDYDKE-RGNEREKERERSRERSKEQRSRGEVEEKKH 403
Query: 352 SVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSM 411
+ D + + K + E + S R + +R K ++
Sbjct: 404 KEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNES 463
Query: 412 EALQMDRSGSG 422
+ RS SG
Sbjct: 464 KEKSNKRSRSG 474
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 89.0 bits (219), Expect = 1e-17
Identities = 62/220 (28%), Positives = 102/220 (46%), Gaps = 27/220 (12%)
Query: 154 VREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHR 213
V E + ++ K TE+ RD + K+E K++R+ REK++++E+ + R
Sbjct: 227 VEELKEKLRKRTEE----------PDRDERLKKE-KQEREEREKEREREREERERKRRRE 275
Query: 214 EGERERAKARARPDNERQKDRGNRE---------RDRDSERKKETERKSEGGKEKERLRD 264
E ERE+ +AR R +R + R R RD +R + ER+ +++ R R
Sbjct: 276 EEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRS 335
Query: 265 RDRERDRDKGKDRDRRRVKNGEHSWDLDREKNR--EHDKPEKKSASSGEMSKKLSDGTFK 322
DR + + + RDRRR K+ + R K+R E D+ K+ G KK S K
Sbjct: 336 HDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSS---VK 392
Query: 323 DSKAETETEISTRASKSLTTKTSKRRSKNSV--EGDSTSD 360
E ++E + SK TK + + EGD+ S+
Sbjct: 393 SGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432
Score = 84.7 bits (208), Expect = 2e-16
Identities = 55/187 (29%), Positives = 97/187 (51%), Gaps = 13/187 (6%)
Query: 147 QELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKE 206
+E + + RE E R K + + E KER+ R+R+++ + R D+ ++++
Sbjct: 255 EEREKEREREREERERKRRREEEERE-KERARDRERRKRSRSRSRHSSRTSDRRCSRSRD 313
Query: 207 NGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRD 266
+ +R RE R R++ R R + + +R +R R RD R K +RKS + K R R++D
Sbjct: 314 HKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQD 373
Query: 267 RE-RDRDK-GKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDS 324
R+ ++++K G D + VK+G REK E E K + +K +GT +D
Sbjct: 374 RKSKEKEKRGSDDKKSSVKSG------SREKQSEDTNTESKESD----TKNEVNGTSEDI 423
Query: 325 KAETETE 331
K+E +T+
Sbjct: 424 KSEGDTQ 430
Score = 78.6 bits (192), Expect = 2e-14
Identities = 66/238 (27%), Positives = 111/238 (46%), Gaps = 37/238 (15%)
Query: 154 VREEESRVHKNT---EDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGN 210
V + +SRV + + G A+IK +T + K+K + + R++ KEK +
Sbjct: 201 VGDAQSRVDDHLMGKQHMGYAKIK--ATVEELKEKLRKRTEEPDRDERLKKEKQEREERE 258
Query: 211 RHREGER-ERAKARARPDNERQKDRG-NRE---------------------RDRDSERKK 247
+ RE ER ER + R R + ER+K+R +RE R RD +R +
Sbjct: 259 KEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSR 318
Query: 248 ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSA 307
ER+ +++ R R DR + + + RDRRR K+ + R K+R+ ++ K
Sbjct: 319 SRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK--- 375
Query: 308 SSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTS-DAEGD 364
S E K+ SD D K+ ++ + S+ T++ + +KN V G S +EGD
Sbjct: 376 -SKEKEKRGSD----DKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGD 428
Score = 77.4 bits (189), Expect = 4e-14
Identities = 49/195 (25%), Positives = 94/195 (48%), Gaps = 8/195 (4%)
Query: 139 RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKD 198
+ L R++E D R+E + K + + E + R+RK++ E +E K R +D
Sbjct: 231 KEKLRKRTEEPD----RDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARD 286
Query: 199 KDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKE 258
+++ K + +RH +R +R+R D++R + R R R R +R++ K
Sbjct: 287 RERRK-RSRSRSRHSSRTSDRRCSRSR-DHKRSRSR-ERRRSRSRDRRRSRSHDRSERKH 343
Query: 259 KERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSD 318
+ R RDR R + RD+ + R + ++ E +EK + +K S SG K+ D
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQD-RKSKEKEKRGSDDKKSSVKSGSREKQSED 402
Query: 319 GTFKDSKAETETEIS 333
+ +++T+ E++
Sbjct: 403 TNTESKESDTKNEVN 417
Score = 66.2 bits (160), Expect = 8e-11
Identities = 53/225 (23%), Positives = 94/225 (41%), Gaps = 33/225 (14%)
Query: 186 EELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSER 245
EELKE + R ++ D++ ER K + ER+K+R +R+ +R
Sbjct: 228 EELKEKLRKRTEEPDRD---------------ERLKKEKQEREEREKEREREREERERKR 272
Query: 246 KK-ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEH----------SWDLDRE 294
++ E ER+ E +++ER R R R R R + DRR ++ +H S DR
Sbjct: 273 RREEEEREKERARDRER-RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR 331
Query: 295 KNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVE 354
++R HD+ E+K S ++ K K +++ + K SK + K +
Sbjct: 332 RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK------SKEKEKRGSD 385
Query: 355 GDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSAR 399
+S G +D + + + NE++ I G +
Sbjct: 386 DKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQ 430
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 89.0 bits (219), Expect = 1e-17
Identities = 62/220 (28%), Positives = 102/220 (46%), Gaps = 27/220 (12%)
Query: 154 VREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHR 213
V E + ++ K TE+ RD + K+E K++R+ REK++++E+ + R
Sbjct: 227 VEELKEKLRKRTEE----------PDRDERLKKE-KQEREEREKEREREREERERKRRRE 275
Query: 214 EGERERAKARARPDNERQKDRGNRE---------RDRDSERKKETERKSEGGKEKERLRD 264
E ERE+ +AR R +R + R R RD +R + ER+ +++ R R
Sbjct: 276 EEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRS 335
Query: 265 RDRERDRDKGKDRDRRRVKNGEHSWDLDREKNR--EHDKPEKKSASSGEMSKKLSDGTFK 322
DR + + + RDRRR K+ + R K+R E D+ K+ G KK S K
Sbjct: 336 HDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSS---VK 392
Query: 323 DSKAETETEISTRASKSLTTKTSKRRSKNSV--EGDSTSD 360
E ++E + SK TK + + EGD+ S+
Sbjct: 393 SGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432
Score = 84.7 bits (208), Expect = 2e-16
Identities = 55/187 (29%), Positives = 97/187 (51%), Gaps = 13/187 (6%)
Query: 147 QELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKE 206
+E + + RE E R K + + E KER+ R+R+++ + R D+ ++++
Sbjct: 255 EEREKEREREREERERKRRREEEERE-KERARDRERRKRSRSRSRHSSRTSDRRCSRSRD 313
Query: 207 NGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRD 266
+ +R RE R R++ R R + + +R +R R RD R K +RKS + K R R++D
Sbjct: 314 HKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQD 373
Query: 267 RE-RDRDK-GKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDS 324
R+ ++++K G D + VK+G REK E E K + +K +GT +D
Sbjct: 374 RKSKEKEKRGSDDKKSSVKSG------SREKQSEDTNTESKESD----TKNEVNGTSEDI 423
Query: 325 KAETETE 331
K+E +T+
Sbjct: 424 KSEGDTQ 430
Score = 78.6 bits (192), Expect = 2e-14
Identities = 66/238 (27%), Positives = 111/238 (46%), Gaps = 37/238 (15%)
Query: 154 VREEESRVHKNT---EDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGN 210
V + +SRV + + G A+IK +T + K+K + + R++ KEK +
Sbjct: 201 VGDAQSRVDDHLMGKQHMGYAKIK--ATVEELKEKLRKRTEEPDRDERLKKEKQEREERE 258
Query: 211 RHREGER-ERAKARARPDNERQKDRG-NRE---------------------RDRDSERKK 247
+ RE ER ER + R R + ER+K+R +RE R RD +R +
Sbjct: 259 KEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSR 318
Query: 248 ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSA 307
ER+ +++ R R DR + + + RDRRR K+ + R K+R+ ++ K
Sbjct: 319 SRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK--- 375
Query: 308 SSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTS-DAEGD 364
S E K+ SD D K+ ++ + S+ T++ + +KN V G S +EGD
Sbjct: 376 -SKEKEKRGSD----DKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGD 428
Score = 77.4 bits (189), Expect = 4e-14
Identities = 49/195 (25%), Positives = 94/195 (48%), Gaps = 8/195 (4%)
Query: 139 RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKD 198
+ L R++E D R+E + K + + E + R+RK++ E +E K R +D
Sbjct: 231 KEKLRKRTEEPD----RDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARD 286
Query: 199 KDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKE 258
+++ K + +RH +R +R+R D++R + R R R R +R++ K
Sbjct: 287 RERRK-RSRSRSRHSSRTSDRRCSRSR-DHKRSRSR-ERRRSRSRDRRRSRSHDRSERKH 343
Query: 259 KERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSD 318
+ R RDR R + RD+ + R + ++ E +EK + +K S SG K+ D
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQD-RKSKEKEKRGSDDKKSSVKSGSREKQSED 402
Query: 319 GTFKDSKAETETEIS 333
+ +++T+ E++
Sbjct: 403 TNTESKESDTKNEVN 417
Score = 66.2 bits (160), Expect = 8e-11
Identities = 53/225 (23%), Positives = 94/225 (41%), Gaps = 33/225 (14%)
Query: 186 EELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSER 245
EELKE + R ++ D++ ER K + ER+K+R +R+ +R
Sbjct: 228 EELKEKLRKRTEEPDRD---------------ERLKKEKQEREEREKEREREREERERKR 272
Query: 246 KK-ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEH----------SWDLDRE 294
++ E ER+ E +++ER R R R R R + DRR ++ +H S DR
Sbjct: 273 RREEEEREKERARDRER-RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR 331
Query: 295 KNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVE 354
++R HD+ E+K S ++ K K +++ + K SK + K +
Sbjct: 332 RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK------SKEKEKRGSD 385
Query: 355 GDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSAR 399
+S G +D + + + NE++ I G +
Sbjct: 386 DKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQ 430
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 88.6 bits (218), Expect = 2e-17
Identities = 61/224 (27%), Positives = 111/224 (49%), Gaps = 16/224 (7%)
Query: 94 RIVAGHEPERTNELLQIIGKCCLNKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKN 153
+ ++ + N LQ++ ++K + + + + E++ R + K
Sbjct: 3 KAISSRAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKE 62
Query: 154 VREEESRVHKNTEDR----GDAEIK--ERSTSRDRKQKEELKEDRKPREKDKDKEKAKEN 207
RE E R + ++R G E K + R+RK++ KE+++ EK+K K+K K+
Sbjct: 63 RREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKE 122
Query: 208 GGNRHREG-ERERAKARARPDN-ERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDR 265
G +EG ERER + R R + ER++ + RE++R+ + +K+ ERK G KE+ER
Sbjct: 123 RGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKE 182
Query: 266 DRER--------DRDKGKDRDRRRVKNGEHSWDLDREKNREHDK 301
+ER +R K ++R RR + E +R+K R+ D+
Sbjct: 183 RKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR 226
Score = 88.6 bits (218), Expect = 2e-17
Identities = 49/160 (30%), Positives = 88/160 (55%), Gaps = 8/160 (5%)
Query: 132 EKGE-VKGRASLTSRSQELDNKNVREEESRVHKNTEDRG--DAEIKERSTSRDRKQKEEL 188
+KGE K R +E +NK E+E R K ++RG E KER +RK++E
Sbjct: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
Query: 189 KEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKE 248
+ +RK E++K++E+ + R + GE+E + ++++R +ER ++ ERK+
Sbjct: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER 205
Query: 249 TERKSEGGKEKERLRDRDRE-----RDRDKGKDRDRRRVK 283
ERK E K++ER ++R ++ R++++GK + R K
Sbjct: 206 RERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 86.3 bits (212), Expect = 8e-17
Identities = 58/174 (33%), Positives = 95/174 (54%), Gaps = 12/174 (6%)
Query: 133 KGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR 192
K E KG R ++ K RE+E++ + E R E KER + ++ E KE+R
Sbjct: 83 KKEKKGERKKEERERK---KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEER 139
Query: 193 KPREKDKDKEKAKENGGNRHREGERERAKARARPD-NERQKDRGNRERDRDSERKKETER 251
K RE+ K++E+ KE R +E ER+ K R R E++++R +ER ERKK
Sbjct: 140 K-REERKERERKKEE---REKERERKERKKRERKQVGEKEEERKEKER---KERKKRERN 192
Query: 252 KSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
+ E KE+ER R+R+++R K ++R + R K+ + +W ++E+ + K KK
Sbjct: 193 RKERKKERERKERRERKKERKKKEERKKERQKDRQTNW-REKERGKRERKERKK 245
Score = 84.3 bits (207), Expect = 3e-16
Identities = 62/215 (28%), Positives = 108/215 (50%), Gaps = 25/215 (11%)
Query: 154 VREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHR 213
+RE E + E + KER + R ++++E K R+ REK++ +E+ K+ +
Sbjct: 38 IREREREIETRKEGK-----KERESERKKERREREKRKRE-REKERKRERGKKEKKGERK 91
Query: 214 EGERERAKARARPDN------ERQKDRGNRERDRDS----ERKKETERKSEGGKEKERLR 263
+ ERER K R +N E++K + +ER R S ER+++ ERK E KE+ER +
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
Query: 264 -DRDRERDRDKGKDRDRRRV-------KNGEHSWDLDREKNREHDKPEKKSASSGEMSKK 315
+R++ER+R + K R+R++V K E RE+NR+ K E++ E K+
Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKE 211
Query: 316 LSDGTFKDSKAETETEISTRASKSLTTKTSKRRSK 350
+ + + + + + R K + K R K
Sbjct: 212 RKKKEERKKERQKDRQTNWR-EKERGKRERKERKK 245
Score = 77.4 bits (189), Expect = 4e-14
Identities = 50/163 (30%), Positives = 88/163 (53%), Gaps = 13/163 (7%)
Query: 122 DDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRD 181
++ R+ EK +G + +E + +E + + E+R E KER ++
Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Query: 182 RKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDR 241
++KE +++RK RE+ + EK +E +E ER+ K R R ER+K+R +ER
Sbjct: 153 EREKERERKERKKRERKQVGEKEEE-----RKEKERKERKKRERNRKERKKERERKER-- 205
Query: 242 DSERKKETERKSEGGKEKERLRDRD---RERDRDKGKDRDRRR 281
ERKKE ++K E ++KER +DR RE++R K + ++R++
Sbjct: 206 -RERKKERKKKEE--RKKERQKDRQTNWREKERGKRERKERKK 245
Score = 74.7 bits (182), Expect = 2e-13
Identities = 50/196 (25%), Positives = 96/196 (48%), Gaps = 26/196 (13%)
Query: 165 TEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARA 224
T+ +EI+ER ++ E KE +K RE ++ KE+ + R RE ER+R + +
Sbjct: 30 TQPGWQSEIRERE-----REIETRKEGKKERESERKKERREREKRKREREKERKRERGKK 84
Query: 225 RPDNERQKD-----RGNRERD----RDSERKKETERKSEGGKEKE-RLRDRDRERDRDKG 274
ER+K+ + RE++ + E++K+ E+K G KE + R+R ER R++
Sbjct: 85 EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER 144
Query: 275 KDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEIST 334
K+R+R++ E+ +E ++ E+K ++ +K + K+ K + E +
Sbjct: 145 KERERKK-----------EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR 193
Query: 335 RASKSLTTKTSKRRSK 350
+ K + +R K
Sbjct: 194 KERKKERERKERRERK 209
Score = 53.9 bits (128), Expect = 4e-07
Identities = 34/140 (24%), Positives = 69/140 (49%), Gaps = 2/140 (1%)
Query: 215 GERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKG 274
G + + R R R++ + RE +R ER++ +RK E KE++R R + ++ K
Sbjct: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
Query: 275 KDRDR-RRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEIS 333
++R+R +R + E+ ++EK ++ +K E+ S ++ + ++ + E E +
Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Query: 334 TRASKSLTTKTSKRRSKNSV 353
R K K K+R + V
Sbjct: 153 ER-EKERERKERKKRERKQV 171
Score = 48.9 bits (115), Expect = 1e-05
Identities = 37/188 (19%), Positives = 77/188 (40%), Gaps = 6/188 (3%)
Query: 237 RERDRDSERKKETERKSEGGKEKERL----RDRDRERDRDKGKDRDRRRVKNGEHSWDLD 292
RER+R+ E +KE +++ E ++KER R R+RE++R + + + ++ + + +
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
Query: 293 REKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNS 352
+ + + +K ++ + KK T K+ K E R + + + R K
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
Query: 353 VEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSAR--PAPPRVKRQDS 410
+ G +++ E E + R+ R R R K+++
Sbjct: 159 ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218
Query: 411 MEALQMDR 418
+ Q DR
Sbjct: 219 KKERQKDR 226
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 84.7 bits (208), Expect = 2e-16
Identities = 61/239 (25%), Positives = 105/239 (43%), Gaps = 20/239 (8%)
Query: 144 SRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEK 203
SRS+ + K + E R H++ R ++ R S+D+ K+ E+ +E DK +
Sbjct: 43 SRSRSRERKRKSDNEGRKHRS---RSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGR 99
Query: 204 AK----ENGGNRHREGERE--------RAKARARPDNERQKDRGNRERDRDSERKKETER 251
+ ENG +RH+ ER+ R+++R R R ++R + R R ERKK R
Sbjct: 100 ERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRER-KKSRSRSRERKKSRSR 158
Query: 252 KSEGGKEKERLRDRDRE-RDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSG 310
E K + R R+R R R R + + R R R ++ + R++ + +KP + S S
Sbjct: 159 SRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRS-- 216
Query: 311 EMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAG 369
+S+ S F+ + + + K ++R K VE + A G
Sbjct: 217 -LSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGG 274
Score = 65.5 bits (158), Expect = 1e-10
Identities = 64/253 (25%), Positives = 101/253 (39%), Gaps = 35/253 (13%)
Query: 178 TSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARP-DNE----RQK 232
T RD E+ DR ++K++ + H R R++ R R DNE R +
Sbjct: 6 TERDGLAPEKTSPDRD-KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
Query: 233 DRGNRERDRDSERKKETERKSEGGKEKERLRDRDRER------DRDKGKDRDRRRVKNGE 286
R R +S+ K + KSE +KE D+ RER D+ K ++R+ +
Sbjct: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
Query: 287 HSWDLDRE-KNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTS 345
HS RE ++R + KKS S KK + + K+ + + R +S + S
Sbjct: 125 HSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 184
Query: 346 KRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPP-- 403
+ R + + S +D+ + E P RR R S P+PP
Sbjct: 185 RHRHRTRSRSRTRS--------RSRDRKKRIEKP----------RRFSRSLSRTPSPPPF 226
Query: 404 --RVKRQDSMEAL 414
R D+ EAL
Sbjct: 227 RGRNTAMDAQEAL 239
Score = 57.8 bits (138), Expect = 3e-08
Identities = 41/174 (23%), Positives = 75/174 (43%), Gaps = 2/174 (1%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
E KGR L S D +E +S ++ E + RS SR+RK+ +
Sbjct: 92 EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE 151
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
RK + + + +E+ K +R R+ R R+++R+R + + +R R R +RKK E+
Sbjct: 152 RK-KSRSRSRERKKSRSRSRERK-RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEK 209
Query: 252 KSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
+ R R R+ D + E + L ++ +E + +K+
Sbjct: 210 PRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 263
Score = 52.8 bits (125), Expect = 1e-06
Identities = 48/224 (21%), Positives = 94/224 (41%), Gaps = 23/224 (10%)
Query: 120 SSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTS 179
SS++ R E+ +GR+ SRS+E +++ SR K + R K RS S
Sbjct: 104 SSENGEDRHKRKERKSSRGRSHSRSRSRERRHRS----RSRERKKSRSRSRERKKSRSRS 159
Query: 180 RDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRER 239
R+RK+ +RK R + + + ++ RHR R R++ R+R +R+R
Sbjct: 160 RERKKSRSRSRERKRRIRSRSRSRS------RHRHRTRSRSRTRSR----------SRDR 203
Query: 240 DRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREH 299
+ E+ + R R R+ D + R R K + + + + ++
Sbjct: 204 KKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 263
Query: 300 DKPEKKSASSG---EMSKKLSDGTFKDSKAETETEISTRASKSL 340
+ +A+ G ++ L+ GT + +++ +K+L
Sbjct: 264 QEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQAKAL 307
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 81.3 bits (199), Expect = 3e-15
Identities = 48/143 (33%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 167 DRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARP 226
+R D KE+ Q EDR+ RE+++ + ++E +R RE +R R K +R
Sbjct: 2089 ERFDVGPKEKPLEEPDAQGRA-SEDRR-RERERGRNWSRERDWDRPREWDRHRDKDSSRD 2146
Query: 227 DNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGE 286
+ ++ NR+R+R+++R KE +R E + +ER RDR R+RDR + ++RDR + ++ E
Sbjct: 2147 WDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRE 2206
Query: 287 HSWD-LDREKNREHDKPEKKSAS 308
D DR K++E + K AS
Sbjct: 2207 RGRDRKDRSKSKESARDPKPEAS 2229
Score = 66.2 bits (160), Expect = 8e-11
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 7/154 (4%)
Query: 176 RSTSRDRKQKEELKEDRKPREKDKDKEKAKENGG-NRHREGERERAKARARP-DNERQKD 233
R+ + + +Q+E D P+EK ++ A+ +R RE ER R +R R D R+ D
Sbjct: 2079 RNQTFEGRQRERF--DVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWD 2136
Query: 234 RGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDR 293
R RD+DS R + R+ +++ER DR +E DR + + R+R R ++ D R
Sbjct: 2137 R---HRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSR 2193
Query: 294 EKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAE 327
+ R+ DK + + S + +D K E
Sbjct: 2194 SRERDRDKARDRERGRDRKDRSKSKESARDPKPE 2227
Score = 65.9 bits (159), Expect = 1e-10
Identities = 49/154 (31%), Positives = 80/154 (51%), Gaps = 16/154 (10%)
Query: 201 KEKAKENGGNRHREGERERAKARARPDNERQKDRG---NRERDRDSERKKETERKSEGGK 257
+++ + + G + + E A+ RA D R+++RG +RERD D R+ + R + +
Sbjct: 2086 RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSR 2145
Query: 258 E----KERLRDRDRERDRDKGK--DRDRRRVKNGEHS----WDLDREKNREHDKPEKKSA 307
+ +ER +RDRER+ D+GK DR R R +N E D DR ++RE D+ + +
Sbjct: 2146 DWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDR 2205
Query: 308 SSGEMSKKLSDGTFKDSKAETETEISTRASKSLT 341
G K S K+S + + E S RAS + T
Sbjct: 2206 ERGRDRKDRSKS--KESARDPKPEAS-RASDAGT 2236
Score = 43.9 bits (102), Expect = 4e-04
Identities = 43/169 (25%), Positives = 70/169 (41%), Gaps = 11/169 (6%)
Query: 213 REGERERAKARARPDNERQK-DRGNRER-----DRDSERKKETERKSEGGKEKERLRDRD 266
REG+ + + +R++ D G +E+ D ++ R+ E G+ R RD D
Sbjct: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWD 2130
Query: 267 RER--DRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDS 324
R R DR + KD R +N E S + DRE+ + K +S ++ D
Sbjct: 2131 RPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRD 2190
Query: 325 KAETETEISTRASKSLTTKTSKRRSKNSVEG-DSTSDAE--GDAGPAGQ 370
++ + +A + K RSK+ D +A DAG A Q
Sbjct: 2191 RSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDAGTASQ 2239
Score = 43.5 bits (101), Expect = 6e-04
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 26/143 (18%)
Query: 132 EKGEVKGRASLTSR---------SQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDR 182
E+ + +GRAS R S+E D RE + K++ D +ERS +RDR
Sbjct: 2101 EEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRN-RERSANRDR 2159
Query: 183 -------KQKEELKEDRKPREKDKDKEKAKENGGNRHREGE--RERAKARARPDNERQKD 233
K+ + +E + RE+++D+ + ++ +R R+ + R+R + R R D + K+
Sbjct: 2160 EREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKE 2219
Query: 234 RGNRERDRDSERKKETERKSEGG 256
+ K E R S+ G
Sbjct: 2220 SAR-------DPKPEASRASDAG 2235
Score = 30.4 bits (67), Expect = 5.1
Identities = 46/200 (23%), Positives = 75/200 (37%), Gaps = 22/200 (11%)
Query: 277 RDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDG-TFKDSKAETETEISTR 335
R +R + E + R + R P S S +D T + E+ +E +
Sbjct: 66 RQPKRTERVEQFLTIARRRGRR-SMPVSLEDSGEPTSCPATDAETASEGSVESASETRSG 124
Query: 336 ASKSLTTKTSKRRSKNSVEG----DSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRR 391
+ T + S V+G D TSD++ D E+ N L +
Sbjct: 125 PQSASTAVKERPASSEKVKGGDDHDDTSDSDSDG----------LTLKELQNRLRRKREQ 174
Query: 392 IP--RPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAP 449
P RP + R KR++ A + S TV V+ +N DQ VV A
Sbjct: 175 EPTERPLKGIQSRLRKKRREEGPAETVGSEASD-TVEGVLPSKQEPEN---DQGVVSQAG 230
Query: 450 QLSEMSEIEMVTAVELEEEE 469
+ S++E A ++++EE
Sbjct: 231 KDDRESKLEGKAAQDIKDEE 250
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 81.3 bits (199), Expect = 3e-15
Identities = 96/382 (25%), Positives = 165/382 (43%), Gaps = 56/382 (14%)
Query: 121 SDDAVRRVLAGEKGEVKG-RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTS 179
SDD + + E+GE++ R +T R N R E+S + ED D+ +
Sbjct: 4 SDDRDSKRDSLEEGELRDHRMEITIR-----NSPYRREDSMEDRGEED--DSLAIKPPQQ 56
Query: 180 RDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKD----RG 235
RK+K ++D K +EK + K KE R + E+ KAR + +++++
Sbjct: 57 MSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHS 116
Query: 236 NRERDR--DSERKKETERK-SEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLD 292
RERDR ERK+E ERK E KE+ ++R+R R ++ K+R+ RR + H
Sbjct: 117 RRERDRLEQLERKRERERKMREQQKEQREQKERER-RAEERRKEREARREVSAHH----- 170
Query: 293 REKNREHDKPEKKSASSGEMSK--------KLSDG--TFKDSKAETE------TEISTRA 336
+ D +K AS S +L DG K+ K E +IS
Sbjct: 171 --RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSE 228
Query: 337 SKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPG 396
K+ + ++S S + E + + E + + ++SE E E E +
Sbjct: 229 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG-------S 281
Query: 397 SARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESH----NSDNEEDDQFVVEAAPQLS 452
++ A + + S E + D + V+ ES + ++EE ++ V E PQ S
Sbjct: 282 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 341
Query: 453 EMSEIEMV------TAVELEEE 468
++E + V + +EL++E
Sbjct: 342 ALTEGDYVPDSPALSPIELKQE 363
Score = 57.4 bits (137), Expect = 4e-08
Identities = 79/359 (22%), Positives = 141/359 (39%), Gaps = 58/359 (16%)
Query: 144 SRSQELDNK--NVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDK 201
S+S + D+K ++ E E R H+ ++ + + DR ++++ + P++ + K
Sbjct: 2 SQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSR-K 60
Query: 202 EKAKENGGNRHREGERERAKARAR-PDNERQKDRGNRERDRDSERKKETERKSEGGKEKE 260
EK HR+ E+ + K AR + ER+ +R R R+ + ++E ER+ +E
Sbjct: 61 EKV------HHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMARE 114
Query: 261 RLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDRE-KNREHDKPEKKSASSGEMSKKLSDG 319
R RERDR + +R R R + RE K RE E++
Sbjct: 115 HSR---RERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR 171
Query: 320 TFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETP 379
T ++ + S + S +++ R + E G + V E
Sbjct: 172 TMRE-------DYSDKVKASHWSRSPPRPPRERFE-------------LGDGRKPVKEEK 211
Query: 380 EIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNEE 439
+L S+++ I +R+ S SGSG S+ EE
Sbjct: 212 MEERDLLSDLQDISDS----------ERKTSSAESSSAESGSG------------SEEEE 249
Query: 440 DDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKE 498
+++ E SE SE E E EEEE+ G ++ E + ++ + E+E
Sbjct: 250 EEEEEEEEEGSTSEESEEE--EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 306
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 80.9 bits (198), Expect = 3e-15
Identities = 72/308 (23%), Positives = 136/308 (44%), Gaps = 16/308 (5%)
Query: 133 KGEVKGRASLTSRSQELDNKNVREEESRVHKNTE-DRGDAEIKERSTSRDRKQKEELKED 191
K + K A +S ++ D+K+ +++ +V KN + D ++K+ + S D + + K++
Sbjct: 285 KKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDS-KDE 343
Query: 192 RKPREKDKDKEKA--KENGGNRHREG-ERERAKARARPDNERQKDRGNRERDRDSERKKE 248
RK +KDK K K K+ ++ E + E A+ ++ R + ++ D+ + KK
Sbjct: 344 RKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKI 403
Query: 249 TERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSAS 308
T + + + +D ++D+ K +++ VKN E S D D E + K +K
Sbjct: 404 TFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKK 463
Query: 309 SGEMSKKLSDGTFKDSK---AETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEG-D 364
+ SKK D KD+K TE E K K+ SK ++ D+ D E D
Sbjct: 464 GKKDSKK--DDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTD 521
Query: 365 AGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSAR-----PAPPRVKRQDSMEALQMDRS 419
A K+ + +I + + + +PG+ + + + +E+ + R
Sbjct: 522 AEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRM 581
Query: 420 GSGKTVSN 427
S KT N
Sbjct: 582 SSKKTTFN 589
Score = 55.1 bits (131), Expect = 2e-07
Identities = 74/379 (19%), Positives = 153/379 (40%), Gaps = 27/379 (7%)
Query: 15 KVIRRPPLTEKLLSKPPFRYLHDIITEVIRMT-GFMKGLYTDAEMKSDNVKDKDAKISFL 73
K+++ PP+ + PFR+L+ T + + K +K D+ K K +
Sbjct: 83 KILQWPPIYTAAREQTPFRHLYTSKTHLKKAEYKKSKDEKGGTPLKKDS-KKKGGSYATN 141
Query: 74 QKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLSSDDAVRRVLAGEK 133
++ +V + A + + HE E++ + N S + +K
Sbjct: 142 PESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSK---SSSETNPESQNSKTVSKNCSQK 198
Query: 134 GEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRD------RKQKEE 187
+ + S + ++ L KN +++ + K + D E S + D + E
Sbjct: 199 DKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDES 258
Query: 188 LKEDRKPREKDKDKEK----------AKENGGNRHREGERERAKARARPDNERQKDRGNR 237
+ D R ++ K K+ N + + E ++ + ++ + +
Sbjct: 259 INFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVK 318
Query: 238 ERDRDSERKKETE-RKSEGGKEKERLRD--RDRERDRDKGKDRDRRRVKNGEHSWDLDRE 294
+ D+ + KK+TE +E G K+ +D +D+++ + K +D ++ + D +
Sbjct: 319 KDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAK 378
Query: 295 KNREHDKPEKKSASSGEMSKKLSDGTFK-DSKAETETEISTRASKSLTTKTSKRRSKNSV 353
R + KK++ + + K TF DS++E E++ S + K K SK +K SV
Sbjct: 379 DARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKK-DKKDSKTDNKKSV 437
Query: 354 EGDSTSDAEGDAGPAGQDK 372
+ D S + D+ P G K
Sbjct: 438 KNDEES-TDADSEPKGDSK 455
Score = 53.1 bits (126), Expect = 7e-07
Identities = 83/433 (19%), Positives = 165/433 (38%), Gaps = 76/433 (17%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
EK + + A T +N+ ++ +S N E + + + + +D+K + K+
Sbjct: 150 EKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKT 209
Query: 192 ----------------RKPREKDKDKEKAKENGGNRH-----REGERERAKARARPDNER 230
R D E EN N + + E A N
Sbjct: 210 NTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYS 269
Query: 231 QKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDK-----GKDRDRRRVKNG 285
Q + N KK+T++ ++ + E +D ++D K KD ++ VK
Sbjct: 270 QNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKD 329
Query: 286 EHSWDL------DREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKS 339
S D D K+ + DK + K + +KK + T +S + +R K
Sbjct: 330 TESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKK 389
Query: 340 LTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSAR 399
+ K++ + + S++E ++ + +D+ + + + N+ S +
Sbjct: 390 ASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSE 449
Query: 400 PAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEM 459
P + DS + + ++ G D+++DD+ + A + +E +E+E
Sbjct: 450 P------KGDSKKGKKDEKKG-------------KKDSKKDDK--KKDAKKNAESTEME- 487
Query: 460 VTAVELEEEEKHG----GLVKKI-LETKKDYE----KLQQSPKPG------------EKE 498
+ +EL++++KH G K I + +KD E + +S K G E E
Sbjct: 488 -SDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESE 546
Query: 499 RSLFESAWKKEKD 511
SL++ KK+ D
Sbjct: 547 ESLYKPGAKKKID 559
Score = 50.1 bits (118), Expect = 6e-06
Identities = 63/290 (21%), Positives = 120/290 (41%), Gaps = 41/290 (14%)
Query: 132 EKGEVKGRASLTSRSQELDNKN--VREEESRVHKNTEDRGDAEIKE--RSTSRDRK---- 183
E G+ K A SR+ + +KN +++ ++ +T+ + E KE + +D+K
Sbjct: 373 ESGDAKD-ARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKT 431
Query: 184 -QKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRD 242
K+ +K D + + D + + + G ++G+++ K + D ++ + E D +
Sbjct: 432 DNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLE 491
Query: 243 SERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKP 302
++ K+ ++ +G K +D ++D K + + K + D
Sbjct: 492 LKKDKKHSKEKKGSK-------KDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTE 544
Query: 303 EKKSASSGEMSKKL--SDGTFKDSKAE-TETEISTRASKSLTTKTSKRRSKNSVEGDSTS 359
++S KK+ SDGT +SK E E++ R S TT K G+ S
Sbjct: 545 SEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEK--------GEKAS 596
Query: 360 DAEGDAGPAGQDKSEVPE-TPEIPNELSSNIRRI------PRPGSARPAP 402
P ++K +P P +P S +RR+ P P R AP
Sbjct: 597 TGR---VPPSREKPPLPACEPSLP---SPKVRRLCWCKMPPPPPKPRYAP 640
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 80.9 bits (198), Expect = 3e-15
Identities = 72/291 (24%), Positives = 118/291 (40%), Gaps = 44/291 (15%)
Query: 117 NKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKER 176
N D +V K + + ++ S+S+E D+K+ R EE R+ ++ R +KE+
Sbjct: 441 NSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEK 500
Query: 177 STSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGN 236
D K K++ R + K+K K E+ N H D+ + K++
Sbjct: 501 EKQSDSKGKDQ------ERSRSKEKSKQLESKSNEH--------------DHSKSKEKDR 540
Query: 237 RERDRDSERKKETERKSEGGKEKERLRDRDRER-------DRDKGKDRDRRRVKNGEHSW 289
R + R E + S + +ER R RDR R DRD+ + ++ R + E+
Sbjct: 541 RAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYR- 599
Query: 290 DLDREKNREHDKPEKKSAS---------SGEMSKKLSDGTFKDSKAETETEISTRASKSL 340
R ++RE P +S S S ++ S KD E++ S R S
Sbjct: 600 RRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSE 659
Query: 341 TTKT--SKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNI 389
+ K SK R NS A+ D P + K + NEL S++
Sbjct: 660 SEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQD-----NELKSSM 705
Score = 79.7 bits (195), Expect = 7e-15
Identities = 89/405 (21%), Positives = 175/405 (43%), Gaps = 64/405 (15%)
Query: 127 RVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKE 186
RV +GE+ +KG S + +E VR +E ++ T+ R +E R +++K K
Sbjct: 373 RVSSGERW-IKGDKSELNEIKENQRSPVRVKERKI---TDHRNVSESPNRKNEKEKKVK- 427
Query: 187 ELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERK 246
D K K++D + E ++++ ++RAK+++R ++ + ++ERD R
Sbjct: 428 ----DHKSNSKERDIRRNSEKD-DKYKNKVKKRAKSKSRSKSKEKSK--SKERDSKHNRN 480
Query: 247 KETERKSEG-GKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKN-REHDKPEK 304
+E +S G++ E +++++++ D KGKD++R R K E S L+ + N +H K ++
Sbjct: 481 EEKRMRSRSKGRDHENVKEKEKQSD-SKGKDQERSRSK--EKSKQLESKSNEHDHSKSKE 537
Query: 305 KSASSGEMSKK--LSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAE 362
K + S++ ++ G + E S S+ + ++T R S E + E
Sbjct: 538 KDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQE 597
Query: 363 GDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQD--SMEALQMDRSG 420
G+ +S TP PG +R R +R+D S E +
Sbjct: 598 --YRRRGRSRSRERRTP---------------PGRSRSKDRRRRRRDSRSSEREESQSRN 640
Query: 421 SGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILE 480
K + SH +N E + + + + + + KK
Sbjct: 641 KDKYRNQESKSSHRKENSESE----------------KRMYSKSRDHNSSNNSREKKADR 684
Query: 481 TKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQ 525
+ + K++QS + E + S+ + +KE EK+R+S++
Sbjct: 685 DQSPFSKIKQSSQDNELKSSMLK----------NKEDEKIRSSVE 719
Score = 77.4 bits (189), Expect = 4e-14
Identities = 73/370 (19%), Positives = 160/370 (43%), Gaps = 60/370 (16%)
Query: 146 SQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAK 205
S+ + KN +E++ + HK+ KER R+ ++ ++ K K R K K + K+K
Sbjct: 413 SESPNRKNEKEKKVKDHKSNS-------KERDIRRNSEKDDKYKNKVKKRAKSKSRSKSK 465
Query: 206 ENGGNRHREGERERAKARARPDNERQKDRGN-RERDRDSERKKETERKSEGGKEKERLRD 264
E ++ R+ + R + + + +D N +E+++ S+ K + + +S ++ ++L
Sbjct: 466 EKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLES 525
Query: 265 RDRERDRDKGKDRDRRR--------VKNGEHSWD-LDREKNREHDKPEKKSASSGEMSKK 315
+ E D K K++DRR + G+HS++ RE++R D+ + + + + +
Sbjct: 526 KSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRS 585
Query: 316 LSDGTFKDSKAETETEISTRA-SKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSE 374
S K+ E E R S+S +T RS++ D+ Q +++
Sbjct: 586 RS----KEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNK 641
Query: 375 VPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHN 434
+ + Q+S + + + S S K + + + ++
Sbjct: 642 ----------------------------DKYRNQESKSSHRKENSESEKRMYSKSRDHNS 673
Query: 435 SDNEED-----DQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQ 489
S+N + DQ Q S+ +E++ + ++ +E+EK ++ +E + K Q
Sbjct: 674 SNNSREKKADRDQSPFSKIKQSSQDNELKS-SMLKNKEDEK----IRSSVEKENQKSKGQ 728
Query: 490 QSPKPGEKER 499
++ EK +
Sbjct: 729 ENDHVHEKNK 738
Score = 69.3 bits (168), Expect = 1e-11
Identities = 53/237 (22%), Positives = 109/237 (45%), Gaps = 11/237 (4%)
Query: 142 LTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDK 201
L S+S E D+ +E++ R + + + K SR R++ R+ R + D+
Sbjct: 523 LESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDR 582
Query: 202 EKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKER 261
++++ +R+RE E R + R+R R +R +DR R++ R SE +E+ +
Sbjct: 583 DRSRSKEYHRYREQEYRR-RGRSRSRERRTPPGRSRSKDR--RRRRRDSRSSE--REESQ 637
Query: 262 LRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKS----ASSGEMSKKLS 317
R++D+ R+++ + ++ + + R+ N ++ EKK+ + ++ +
Sbjct: 638 SRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQ 697
Query: 318 DGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSV-EGDSTSDAEGDAGPAGQDKS 373
D K S + + + R+S + SK + + V E + D E G +DKS
Sbjct: 698 DNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPG-TDEDKS 753
Score = 49.7 bits (117), Expect = 8e-06
Identities = 77/394 (19%), Positives = 145/394 (36%), Gaps = 103/394 (26%)
Query: 142 LTSRSQELDNKNVREEESRVHK--------------NTEDRGDAEIKERSTSRDRKQKEE 187
+ S + + V++EE + HK +++ + ++ + ++ + K K+
Sbjct: 171 ILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKR 230
Query: 188 LKEDRK-PREKDKDKEKAKENGGNRHREGERERAKA---------------------RAR 225
K+ RK R+ K+K+K K++ + E E E +A R
Sbjct: 231 KKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKS 290
Query: 226 PDNERQKDRGNRERDRDSERK---------------KETERKSEG-GKEKERLRDRDRER 269
P +K+R NRER+R+ E + RK +G G + R R R R
Sbjct: 291 PPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSR 350
Query: 270 DRDKGKD-----------RDRRRVKNGEHSW----------------------------- 289
DR + + R RV +GE W
Sbjct: 351 DRFRRSETPPHWRQEMQRAQRMRVSSGER-WIKGDKSELNEIKENQRSPVRVKERKITDH 409
Query: 290 -DLDREKNREHDKPEK-KSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKR 347
++ NR+++K +K K S + + + KD K + + + + +KS + SK
Sbjct: 410 RNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVK---KRAKSKSRSKSKE 466
Query: 348 RSKNSVEGDSTSDAEGD----AGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPP 403
+SK S E DS + + + G+D V E + + + R ++
Sbjct: 467 KSK-SKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLES 525
Query: 404 RVKRQDSMEALQMDRSGSGKTVSNVITESHNSDN 437
+ D ++ + DR ++ IT+ +S N
Sbjct: 526 KSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYN 559
Score = 33.9 bits (76), Expect = 0.46
Identities = 69/378 (18%), Positives = 133/378 (35%), Gaps = 77/378 (20%)
Query: 185 KEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARP-DNERQKDRGNRERDRDS 243
K ++K++ K R K + + + + + + + E+ K R + R
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239
Query: 244 ERKKETERKSEGGK------EKERLR---------------DRDRERDRDKGKDRDRRRV 282
+ KKE +++ + K E E L +R R D +
Sbjct: 240 KHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKER 299
Query: 283 KNGEHSWDLDREKNREHDKPEKKSAS---------SGEMSKKLSDGTFKDSKAETETEIS 333
KN E RE+ RE + P + AS SG K ++ +
Sbjct: 300 KNRE------RERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRF 353
Query: 334 TRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIP 393
R+ + +R++ +G DKSE+ NE+ N R
Sbjct: 354 RRSETPPHWRQEMQRAQRMRVSSGERWIKG-------DKSEL-------NEIKENQR--- 396
Query: 394 RPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNS---------DNEEDDQFV 444
+P RVK + + + S + K + H S ++E+DD++
Sbjct: 397 -------SPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYK 449
Query: 445 VEAAPQLSEMSEIE-MVTAVELEEEEKHGGLVKKILETK---KDYEKLQQSPKPGEKERS 500
+ + S + + E + KH +K + ++ +D+E +++ K + +
Sbjct: 450 NKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGK 509
Query: 501 LFESAWKKEKDIVSKEIE 518
E + KEK SK++E
Sbjct: 510 DQERSRSKEK---SKQLE 524
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 80.5 bits (197), Expect = 4e-15
Identities = 102/394 (25%), Positives = 171/394 (43%), Gaps = 67/394 (17%)
Query: 120 SSDDAVRRVLAGEKGEVKG-RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERST 178
+SDD + + E+GE++ R +T R N R E+S + ED D+ +
Sbjct: 37 NSDDRDSKRDSLEEGELRDHRMEITIR-----NSPYRREDSMEDRGEED--DSLAIKPPQ 89
Query: 179 SRDRKQKEELKEDRKPREKDKDKEKAKENGGN---RHREGERERAKA------RARPDNE 229
RK+K ++D K +EK + + + E G + + +E E ER K +AR + E
Sbjct: 90 QMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWE 149
Query: 230 RQKDR------GNRERDR--DSERKKETERK-SEGGKEKERLRDRDRERDRDKGKDRDRR 280
RQK R RERDR ERK+E ERK E KE+ ++R+R R ++ K+R+ R
Sbjct: 150 RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERER-RAEERRKEREAR 208
Query: 281 RVKNGEHSWDLDREKNREHDKPEKKSASSGEMSK--------KLSDG--TFKDSKAETE- 329
R + H + D +K AS S +L DG K+ K E
Sbjct: 209 REVSAHH-------RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERD 261
Query: 330 -----TEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNE 384
+IS K+ + ++S S + E + + E + + ++SE E E E
Sbjct: 262 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 321
Query: 385 LSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESH----NSDNEED 440
+ ++ A + + S E + D + V+ ES + ++EE
Sbjct: 322 EETG-------SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEA 374
Query: 441 DQFVVEAAPQLSEMSEIEMV------TAVELEEE 468
++ V E PQ S ++E + V + +EL++E
Sbjct: 375 EEEVGEGTPQSSALTEGDYVPDSPALSPIELKQE 408
Score = 62.8 bits (151), Expect = 9e-10
Identities = 71/352 (20%), Positives = 140/352 (39%), Gaps = 37/352 (10%)
Query: 170 DAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHR---------------- 213
D ++E+ +++++K E+K + ++D ++ +E HR
Sbjct: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSM 73
Query: 214 --EGERERAKARARPDNERQKDRGNRERD-RDSERKKETERKSEGGKEKERLRDRDRERD 270
GE + + A P +K++ + +D + E+++ +EGGK R+++++RE +
Sbjct: 74 EDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKH-ARVKEKEREHE 132
Query: 271 RDKGKDRDRRRVKNGEHSWDLD--REKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAET 328
R K R R W+ RE REH + E+ E ++ + K +
Sbjct: 133 RRK---RHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 189
Query: 329 ETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSN 388
E + R ++ + RR ++ D D A P P EL
Sbjct: 190 EQKERERRAEERRKEREARREVSAHHRTMRED-YSDKVKASHWSRSPPRPPRERFELGDG 248
Query: 389 IRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITES--HNSDNEEDDQFVVE 446
+ + +++ +D + LQ D S S + S+ + S S +EE+++ E
Sbjct: 249 RKPVKE--------EKMEERDLLSDLQ-DISDSERKTSSAESSSAESGSGSEEEEEEEEE 299
Query: 447 AAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKE 498
+ S E E E EEEE+ G ++ E + ++ + E+E
Sbjct: 300 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 351
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 80.1 bits (196), Expect = 6e-15
Identities = 95/383 (24%), Positives = 165/383 (43%), Gaps = 56/383 (14%)
Query: 120 SSDDAVRRVLAGEKGEVKGRA-SLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERST 178
+SDD + + E+GE++ +T R N R E+S + ED D+ +
Sbjct: 37 NSDDRDSKRDSLEEGELRDHCMEITIR-----NSPYRREDSMEDRGEED--DSLAIKPPQ 89
Query: 179 SRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKD----R 234
RK+K ++D K +EK + K KE R + E+ KAR + +++++
Sbjct: 90 QMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREH 149
Query: 235 GNRERDR--DSERKKETERK-SEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDL 291
RERDR ERK+E ERK E KE+ ++R+R R ++ K+R+ RR + H
Sbjct: 150 SRRERDRLEQLERKRERERKMREQQKEQREQKERER-RAEERRKEREARREVSAHH---- 204
Query: 292 DREKNREHDKPEKKSASSGEMSK--------KLSDG--TFKDSKAETE------TEISTR 335
+ D +K AS S +L DG K+ K E +IS
Sbjct: 205 ---RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDS 261
Query: 336 ASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRP 395
K+ + ++S S + E + + E + + ++SE E E E +
Sbjct: 262 ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG------- 314
Query: 396 GSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESH----NSDNEEDDQFVVEAAPQL 451
++ A + + S E + D + V+ ES + ++EE ++ V E PQ
Sbjct: 315 SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQS 374
Query: 452 SEMSEIEMV------TAVELEEE 468
S ++E + V + +EL++E
Sbjct: 375 SALTEGDYVPDSPALSPIELKQE 397
Score = 37.7 bits (86), Expect = 0.032
Identities = 68/342 (19%), Positives = 130/342 (38%), Gaps = 44/342 (12%)
Query: 196 EKDKDKEKAKEN---GGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERK 252
EKD K K + R +E E + R + ++R R + E + E +
Sbjct: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
Query: 253 SEGGKEKERLRDRDRERDR--------------------DKGKDRDRRRVKNGEHSWDLD 292
+ + ++ + DR E D +K K++ RVK E +
Sbjct: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERR 123
Query: 293 REKNREHDKP------EKKSASSGEMSKKLSDGTFK-DSKAETETEISTRASKSLTTKTS 345
+ E DK +K+ + E S++ D + + K E E ++ + + K
Sbjct: 124 KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKER 183
Query: 346 KRRS-KNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPR------PGSA 398
+RR+ + E ++ + +D S+ + + S + R PR G
Sbjct: 184 ERRAEERRKEREARREVSAHHRTMREDYSDKVKA----SHWSRSPPRPPRERFELGDGRK 239
Query: 399 RPAPPRVKRQDSMEALQMDRSGSGKTVSNVITES--HNSDNEEDDQFVVEAAPQLSEMSE 456
+++ +D + LQ D S S + S+ + S S +EE+++ E + S E
Sbjct: 240 PVKEEKMEERDLLSDLQ-DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 298
Query: 457 IEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKE 498
E E EEEE+ G ++ E + ++ + E+E
Sbjct: 299 SEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 340
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 80.1 bits (196), Expect = 6e-15
Identities = 102/393 (25%), Positives = 170/393 (43%), Gaps = 67/393 (17%)
Query: 121 SDDAVRRVLAGEKGEVKG-RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTS 179
SDD + + E+GE++ R +T R N R E+S + ED D+ +
Sbjct: 4 SDDRDSKRDSLEEGELRDHRMEITIR-----NSPYRREDSMEDRGEED--DSLAIKPPQQ 56
Query: 180 RDRKQKEELKEDRKPREKDKDKEKAKENGGN---RHREGERERAKA------RARPDNER 230
RK+K ++D K +EK + + + E G + + +E E ER K +AR + ER
Sbjct: 57 MSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWER 116
Query: 231 QKDR------GNRERDR--DSERKKETERK-SEGGKEKERLRDRDRERDRDKGKDRDRRR 281
QK R RERDR ERK+E ERK E KE+ ++R+R R ++ K+R+ RR
Sbjct: 117 QKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERER-RAEERRKEREARR 175
Query: 282 VKNGEHSWDLDREKNREHDKPEKKSASSGEMSK--------KLSDG--TFKDSKAETE-- 329
+ H + D +K AS S +L DG K+ K E
Sbjct: 176 EVSAHH-------RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDL 228
Query: 330 ----TEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNEL 385
+IS K+ + ++S S + E + + E + + ++SE E E E
Sbjct: 229 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 288
Query: 386 SSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESH----NSDNEEDD 441
+ ++ A + + S E + D + V+ ES + ++EE +
Sbjct: 289 ETG-------SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAE 341
Query: 442 QFVVEAAPQLSEMSEIEMV------TAVELEEE 468
+ V E PQ S ++E + V + +EL++E
Sbjct: 342 EEVGEGTPQSSALTEGDYVPDSPALSPIELKQE 374
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 79.0 bits (193), Expect = 1e-14
Identities = 95/424 (22%), Positives = 175/424 (41%), Gaps = 55/424 (12%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRG-DAEIKERSTSRDRKQKEELKEDRKPREKDKDKEK 203
R + +N V+ E+ + N +R + E + R R+R+++ + + +R+ RE+++++E
Sbjct: 381 RGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQREREREREH 440
Query: 204 AKENGGNRHREG-ERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGK----- 257
++ R +E ERERAK R + +RQ +RE++R+ E+ K R +
Sbjct: 441 ERDKERQRRKEEWERERAK---RDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEP 497
Query: 258 -EKERLRDRDRERDRDKGKD---RDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMS 313
+KE + + D+ KD R + K S R + R SAS+ S
Sbjct: 498 PKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRS 557
Query: 314 KKLSD------GTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSD------- 360
S + S++ + + S+R+S+ + S+ RS++ S S
Sbjct: 558 SSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRP 617
Query: 361 ---AEGDAGP----AGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEA 413
+G+ P AG+ + P P P + + +P P +P PR R+ A
Sbjct: 618 SIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEP--TKPGDPREARRKERPA 675
Query: 414 LQMDR----SGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEE 469
R SGSG + S++ + V + +S + +A ++ E+
Sbjct: 676 RTPPRRRTLSGSGSGSGS----SYSGSSSRSRSLSVSSVSSVSSATS-SSSSAHSVDSED 730
Query: 470 KHGGLVKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCK 529
+ L + +SP P + + E K++D V +E K +S Q K
Sbjct: 731 MYADLASPVSSAS------SRSPAPAQTRK---EKGKSKKEDGVKEEKRKRDSSTQP-PK 780
Query: 530 SALP 533
SA P
Sbjct: 781 SAKP 784
Score = 50.1 bits (118), Expect = 6e-06
Identities = 56/256 (21%), Positives = 106/256 (41%), Gaps = 13/256 (5%)
Query: 180 RDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRER 239
R+ ++ E+ D R ++ E + + + E ER + +N R +
Sbjct: 339 REFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPY 398
Query: 240 DRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREH 299
ER++E ER++ +E+ER R+RDRER+R R R R + EH + D+E+ R
Sbjct: 399 HNYRERERERERENR-QRERERERERDRERER-----RQREREREREH--ERDKERQRRK 450
Query: 300 DKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTS 359
++ E++ A E D +D E E E K + + R+++ + +T+
Sbjct: 451 EEWERERAKRDE-----KDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATT 505
Query: 360 DAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRS 419
+ +D ++P+ +S + R R + + S
Sbjct: 506 GPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYS 565
Query: 420 GSGKTVSNVITESHNS 435
GSG + S + S++S
Sbjct: 566 GSGSSRSRSRSSSYSS 581
Score = 41.2 bits (95), Expect = 0.003
Identities = 48/210 (22%), Positives = 81/210 (38%), Gaps = 29/210 (13%)
Query: 147 QELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR--KPREKDKDKEKA 204
Q+LD VR D D E R S++ + +EDR +P+ +D+D E
Sbjct: 36 QDLDGAGVR---------ASDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVN 86
Query: 205 KENGG-------NRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGK 257
+ + G EGE +R + ++ E D D E +E
Sbjct: 87 ELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHELDYDEEVPEE----PAPAV 142
Query: 258 EKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLS 317
+++ E D +KG+ R K G S + +++ E K +KK GE +
Sbjct: 143 QEDEAEKAGAEDDEEKGEGTPREEGKAGVQS--VGEKESLEAAKEKKKEDDDGE----ID 196
Query: 318 DGTFKDSKAETETEISTRASKSLTTKTSKR 347
DG D E E E+ + + + + + R
Sbjct: 197 DGEIDDDDLE-EGEVKDPSDRKVRPRPTCR 225
Score = 37.7 bits (86), Expect = 0.032
Identities = 39/251 (15%), Positives = 95/251 (37%), Gaps = 21/251 (8%)
Query: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR 180
S R + V S +S + +D++++ + + + R A + R
Sbjct: 698 SSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKG 757
Query: 181 DRKQKEELKEDRKPREKDKDKEKAKEN--GGNRHREGERERAKARARPDN---------- 228
K+++ +KE+++ R+ K+ + GG ++ + +P
Sbjct: 758 KSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIK 817
Query: 229 ----ERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKN 284
+ D+G+R+R S++ +++ ++ RDR+ G + R+
Sbjct: 818 LTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQ 877
Query: 285 GEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRAS-----KS 339
+ ++ R+ K S+ + K SD +K+ + +S R K+
Sbjct: 878 NSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKA 937
Query: 340 LTTKTSKRRSK 350
+ +++R+K
Sbjct: 938 VEDAIARKRAK 948
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 77.8 bits (190), Expect = 3e-14
Identities = 99/390 (25%), Positives = 164/390 (42%), Gaps = 61/390 (15%)
Query: 120 SSDDAVRRVLAGEKGEVKGRA-SLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERST 178
+SDD + + E+GE++ +T R N R E+S + ED A +
Sbjct: 37 NSDDRDSKRDSLEEGELRDHCMEITIR-----NSPYRREDSMEDRGEEDDSLAIKPPQQM 91
Query: 179 SRDRKQKEELKEDRKPREKDKDKEKAKEN-GGNRHRE------GERERAKARARPDNERQ 231
SR K E RK ++ + KEK +E+ RHRE E ER K R +
Sbjct: 92 SRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSR 151
Query: 232 KDRGN------RERDRDSERKKETERK-SEGGKEKERLRDRDRERDRDKGKDRDRRRVKN 284
++RGN R+R ERK+E ERK E KE+ ++R+R R ++ K+R+ RR +
Sbjct: 152 RERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERER-RAEERRKEREARREVS 210
Query: 285 GEHSWDLDREKNREHDKPEKKSASSGEMSK--------KLSDG--TFKDSKAETE----- 329
H + D +K AS S +L DG K+ K E
Sbjct: 211 AHH-------RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSD 263
Query: 330 -TEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSN 388
+IS K+ + ++S S + E + + E + + ++SE E E E +
Sbjct: 264 LQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 323
Query: 389 IRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESH----NSDNEEDDQFV 444
++ A + + S E + D + V+ ES + ++EE ++ V
Sbjct: 324 -------SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEV 376
Query: 445 VEAAPQLSEMSEIEMV------TAVELEEE 468
E PQ S ++E + V + +EL++E
Sbjct: 377 GEGTPQSSALTEGDYVPDSPALSPIELKQE 406
Score = 35.4 bits (80), Expect = 0.16
Identities = 71/351 (20%), Positives = 133/351 (37%), Gaps = 53/351 (15%)
Query: 196 EKDKDKEKAKEN---GGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERK 252
EKD K K + R +E E + R + ++R R + E + E +
Sbjct: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
Query: 253 SEGGKEKERLRDRDRERDR--------------------DKGKDRDRRRVKNGEHSWDLD 292
+ + ++ + DR E D +K K++ RVK E +
Sbjct: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERR 123
Query: 293 REKNREHDKP------EKKSASSGEMSKKL--SDGT--FKD------SKAETETEISTRA 336
+ E DK +K+ + E S++ +DG F+D K E E ++ +
Sbjct: 124 KRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQ 183
Query: 337 SKSLTTKTSKRRS-KNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPR- 394
+ K +RR+ + E ++ + +D S+ + + S + R PR
Sbjct: 184 KEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKA----SHWSRSPPRPPRE 239
Query: 395 -----PGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITES--HNSDNEEDDQFVVEA 447
G +++ +D + LQ D S S + S+ + S S +EE+++ E
Sbjct: 240 RFELGDGRKPVKEEKMEERDLLSDLQ-DISDSERKTSSAESSSAESGSGSEEEEEEEEEE 298
Query: 448 APQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKE 498
+ S E E E EEEE+ G ++ E + ++ + E+E
Sbjct: 299 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 77.4 bits (189), Expect = 4e-14
Identities = 89/500 (17%), Positives = 218/500 (43%), Gaps = 46/500 (9%)
Query: 142 LTSRSQEL-DNKNVREEESRVHKNTEDRGDAEIKERSTSRDR-KQKEELKEDRKPREKDK 199
L + +EL + K +RE+E ++ + E + E K R +Q+E L E K + +
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 389
Query: 200 DKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEK 259
K + +E + ER R K + E+ ++ E+ R+ ++ +E E+K+ +EK
Sbjct: 390 QKMRDQEE--RMWEQDERLREKEERMREQEKMWEQV--EKMREEKKMQEQEKKTRDQEEK 445
Query: 260 ----ERLRDRDRE--RDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSAS-SGEM 312
ER+R+R+++ + + ++++ + K E+ W+ + ++ ++ PE+K E
Sbjct: 446 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 505
Query: 313 SKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDK 372
++ + ++ + + E K + + R ++ + + + Q++
Sbjct: 506 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 565
Query: 373 SEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITES 432
+T E + ++ R +++ ++ M Q ++ +
Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK-----------MQE 614
Query: 433 HNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKK---DYEKLQ 489
+E ++ + E ++ E E ++ E+E+ +++ E K+ ++EK+Q
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 674
Query: 490 QSPKPGEKERSLFE-------------SAWKKEKDIVSKEIEKLRTSIQTLCKSALPLGK 536
+ K E+E ++E W +EK +E E +R + + + + +
Sbjct: 675 EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEK---MREEESMREREKKMREEEEMMRE 731
Query: 537 IMDYIQEDVDAMQ-NELQMWHSENR--QHAEALQQEQRITDCAVEPLKAELAELEQLIKD 593
+ +QE + MQ E +MW E + + E + ++QR+ + + + E + ++ I +
Sbjct: 732 QEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWE 791
Query: 594 QQDKICAVKANILKNEEKIQ 613
Q++K+ + + EEK++
Sbjct: 792 QEEKMRDQEEKMRGQEEKMR 811
Score = 68.2 bits (165), Expect = 2e-11
Identities = 74/465 (15%), Positives = 202/465 (43%), Gaps = 60/465 (12%)
Query: 152 KNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNR 211
+ +RE+E + + R + +++E+ + R Q+E+++E+ + RE++K + +E +
Sbjct: 411 ERMREQEKMWEQVEKMREEKKMQEQE-KKTRDQEEKMQEEERIREREKKMREEEETMREQ 469
Query: 212 HREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDR 271
+ +++ + + E Q+ R ++++ E++K E++ + +++E++RD++ +
Sbjct: 470 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 529
Query: 272 DKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETE 331
+K R + + + W+ ++ + D+ +K M KK T + K + E
Sbjct: 530 EKKMWRQEKMREQEDQMWE---QEEKMRDQEQKMWDQEERMEKK----TQEQEKKTWDQE 582
Query: 332 ISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRR 391
R + + + K R + + + ++K + E
Sbjct: 583 EKMREEERMREREKKMREEEEMMREQ------------EEKMQEQEE------------- 617
Query: 392 IPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQL 451
K Q+ E + + + + +E+ + + P+
Sbjct: 618 --------------KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ 663
Query: 452 SEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKD 511
E ++ +++E+EK +KI E +K +K Q E+E+ ++ +E++
Sbjct: 664 KE----KLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQ------EQEKKTWDQEKMREEE 713
Query: 512 IVSKEIEKLRTSIQTLCKSALPLGKIMDYIQEDVDAM-QNELQMWHSENR--QHAEALQQ 568
+ + +K+R + + + + + + +QE + M + E +MW E + + +Q
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 569 EQRITDCAVEPLKAELAELEQLIKDQQDKICAVKANILKNEEKIQ 613
++++ + + ++ E E+ ++DQ++K+ + + EEK++
Sbjct: 774 KEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMR 818
Score = 64.3 bits (155), Expect = 3e-10
Identities = 92/503 (18%), Positives = 205/503 (40%), Gaps = 77/503 (15%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
EK + + R + + + +RE+E ++ K E+ + E KE R +QKE+L E
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Query: 192 RKPREKD----------KDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDR 241
K +E++ +D+E+ R+ + + + E+ +D+ + D+
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563
Query: 242 DSERKKET-ERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD 300
+ +K+T E++ + ++E++R+ +R R+R+K + ++ E EK +E
Sbjct: 564 EERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQ- 622
Query: 301 KPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSD 360
E+K E ++ + ++ + E E + L + K +
Sbjct: 623 --EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM------- 673
Query: 361 AEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSG 420
Q++ ++ E E ++ Q+ ME ++
Sbjct: 674 ---------QEQEKMQEQEE-----------------------KIWEQEKMEKKTQEQEK 701
Query: 421 SGKTVSNVITESHNSDNE----EDDQFVVEAAPQLSEMSEIEMVTAVEL-EEEEKHGGLV 475
+ E + E E+++ + E ++ E E E+ E+EEK
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE 761
Query: 476 KKILETKK---DYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSAL 532
+K+ E ++ EKL + K E+E+ W++E+ + +E EK+R + +
Sbjct: 762 EKMWEQQRLPEQKEKLWEHEKMQEQEK-----IWEQEEKMRDQE-EKMRGQEEKM----- 810
Query: 533 PLGKIMDYIQEDVDAMQNELQMWHSENR---QHAEALQQEQRITDCAVEPLKAELAELEQ 589
G+ ++ E +MW E + Q + QE+++ + ++ + ++ E E+
Sbjct: 811 -RGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEE-KMQGQEEKMREQEE 868
Query: 590 LIKDQQDKICAVKANILKNEEKI 612
++ Q++K+ + + EEKI
Sbjct: 869 KMRGQEEKMREQEEKMRGQEEKI 891
Score = 51.6 bits (122), Expect = 2e-06
Identities = 93/508 (18%), Positives = 205/508 (40%), Gaps = 63/508 (12%)
Query: 128 VLAGEKGEVKGR-------ASLTSRSQELDNKNVREEESRVHKNTEDRG--DAEIKERST 178
++ GE ++ GR A R+ + ++ + + + T++R E+ +
Sbjct: 159 LIPGESKDLAGRLHHSWHFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTI 218
Query: 179 SRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRE 238
+ + +K+ + K + +K + + N R+ ER + N Q++ +E
Sbjct: 219 TNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 278
Query: 239 RDRDSERKKETERKSEGGKEKERLRDRD-RERDRDKGKDRDRRRVKNGEHSWDLDREKNR 297
+ + KK +++ + +++ERLR+++ + R++++ R +R++ E ++ R
Sbjct: 279 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 338
Query: 298 EHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDS 357
E + ++ E +K+ + ++ K + E R + L + + R + D
Sbjct: 339 EQKELREQEEQMQEQEEKMWE---QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 395
Query: 358 TSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMD 417
+ + ++K E E E +R + K +D E +Q +
Sbjct: 396 -EERMWEQDERLREKEERMREQEKMWEQVEKMRE-----EKKMQEQEKKTRDQEEKMQEE 449
Query: 418 RSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKK 477
I E EE+ E + E + + E EE+E + +
Sbjct: 450 ER---------IREREKKMREEE-----ETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 495
Query: 478 ILETKKDYEKLQ-QSPKPGEKERSL--FESAWKKEKDIVSKEIEKLRTSIQTLCKSALPL 534
E + EK+Q Q K E+E + E W +EK + + EK+R
Sbjct: 496 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ--EKMREQ----------- 542
Query: 535 GKIMDYIQEDVDAMQN-ELQMWHSENRQHAEALQQEQRITDCAVEPLKAE---------L 584
D + E + M++ E +MW E R + +QE++ D E ++ E +
Sbjct: 543 ---EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD-QEEKMREEERMREREKKM 598
Query: 585 AELEQLIKDQQDKICAVKANILKNEEKI 612
E E+++++Q++K+ + + + EEK+
Sbjct: 599 REEEEMMREQEEKMQEQEEKMQEQEEKM 626
Score = 43.5 bits (101), Expect = 6e-04
Identities = 61/314 (19%), Positives = 129/314 (41%), Gaps = 24/314 (7%)
Query: 309 SGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPA 368
+GE+ + LS + + KA+ E T+ +L+ + + N ++ + A
Sbjct: 178 AGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLA 237
Query: 369 GQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNV 428
+KSE+ + EL + R A+ P+V+ E + + +
Sbjct: 238 ESEKSEIQLNVK---ELKRKLER------AKFLLPQVQTNTLQEEMWRQEEELREQEKKI 288
Query: 429 ITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDY--- 485
+ +E+ + E ++ E E L E+EK +K L +K+
Sbjct: 289 RKQEEKMWRQEER--LREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQ 346
Query: 486 -EKLQQSPKP----GEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPLGKIMDY 540
E++Q+ + EK R E W++E+ + +E +++R Q + + + +
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE-KQMREQEQKMRDQEERMWEQDER 405
Query: 541 IQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQQDKICA 600
++E + M+ + +MW + E QEQ E E + E+ I++++ K+
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQE----EKMQEEERIREREKKMRE 461
Query: 601 VKANILKNEEKIQK 614
+ + + EEK+QK
Sbjct: 462 EEETMREQEEKMQK 475
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 76.6 bits (187), Expect = 6e-14
Identities = 57/179 (31%), Positives = 85/179 (47%), Gaps = 29/179 (16%)
Query: 155 REEESRVHKNTEDRGDAEI-----KERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGG 209
RE E R +E D + + RS SRDR++KE K K EK KEKA+E
Sbjct: 1151 REMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEK---KEKAQEEPP 1207
Query: 210 NRHREGERERAKA--------------------RARPDNERQKDRGNRERDRDSERKKET 249
+ + + KA RA ER+K R +E + ER+KE
Sbjct: 1208 AKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEA 1267
Query: 250 ERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSAS 308
ER+ E+E+ R+ RERDR++ ++R+R R + + + DRE+ RE D+ + K S
Sbjct: 1268 ERERNRQLEREKRREHSRERDRERERERERDR-GDRDRDRERDRERGRERDRRDTKRHS 1325
Score = 70.9 bits (172), Expect = 3e-12
Identities = 41/109 (37%), Positives = 67/109 (61%), Gaps = 6/109 (5%)
Query: 170 DAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNE 229
+AE ER+ R++++KE+ +E++K REK+ ++E+ ++ + RE RER + R R E
Sbjct: 1238 EAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERER---E 1294
Query: 230 RQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERD-RDKGKDR 277
R++DRG+R+RDR ER +E R+ + K R R R RD+G R
Sbjct: 1295 RERDRGDRDRDR--ERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 68.2 bits (165), Expect = 2e-11
Identities = 53/197 (26%), Positives = 90/197 (45%), Gaps = 46/197 (23%)
Query: 155 REEESRVHKNTEDRG-DAEIKERSTSRDRKQKEELKE---------DRKPREKDKDKEKA 204
RE+E V + +R + E +ER+ S +++++E DR+ +E+ K KEK
Sbjct: 1136 REQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKK 1195
Query: 205 KENGGNR---------------------------------HREGER-ERAKAR-ARPDNE 229
E +E ER ERAK R R +
Sbjct: 1196 SEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQ 1255
Query: 230 RQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSW 289
++++ RE++ + ER ++ ER+ +ER R+R+RER+RD+G DRDR R ++ E
Sbjct: 1256 EEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRG-DRDRDRERDRERGR 1314
Query: 290 DLDREKNREHDKPEKKS 306
+ DR + H + +S
Sbjct: 1315 ERDRRDTKRHSRSRSRS 1331
Score = 53.5 bits (127), Expect = 6e-07
Identities = 38/143 (26%), Positives = 69/143 (48%), Gaps = 18/143 (12%)
Query: 231 QKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWD 290
Q+++ R++ +ER++E ER+ E+E RD+ RE R + + RDRRR
Sbjct: 1135 QREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRR--------- 1185
Query: 291 LDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAE--------TETEISTRASKSLTT 342
+R K++E K EKK + E KL D F+ +KA T+++I + ++
Sbjct: 1186 KERAKSKE-KKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAER 1244
Query: 343 KTSKRRSKNSVEGDSTSDAEGDA 365
+ + + E + + E +A
Sbjct: 1245 AKEREKRRKEQEEEEQKEREKEA 1267
Score = 51.6 bits (122), Expect = 2e-06
Identities = 41/205 (20%), Positives = 95/205 (46%), Gaps = 36/205 (17%)
Query: 179 SRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRE 238
+ R+Q+ ++E RE++ ++ + + R+ RE ++R+R + R+K+R +
Sbjct: 1133 AEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERA-KS 1191
Query: 239 RDRDSERKKETE------------RKSEG------------------GKEKERLRDRD-R 267
+++ SE+K++ + RK++ + ER ++R+ R
Sbjct: 1192 KEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKR 1251
Query: 268 ERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAE 327
+++++ + ++R + E + L+REK REH + E+ E + D +D E
Sbjct: 1252 RKEQEEEEQKEREKEAERERNRQLEREKRREHSR-ERDRERERERERDRGD---RDRDRE 1307
Query: 328 TETEISTRASKSLTTKTSKRRSKNS 352
+ E + T + S+ RS+++
Sbjct: 1308 RDRERGRERDRRDTKRHSRSRSRST 1332
Score = 48.9 bits (115), Expect = 1e-05
Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 5/106 (4%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
E+ E + QE + + RE+E+ +N + + K R SR+R ++ E + +
Sbjct: 1240 ERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLERE---KRREHSRERDRERERERE 1296
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNR 237
R ++D+D+E+ +E G R R + +++R+R R DRG R
Sbjct: 1297 RDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVR--DRGGR 1340
Score = 47.0 bits (110), Expect = 5e-05
Identities = 29/104 (27%), Positives = 58/104 (55%), Gaps = 12/104 (11%)
Query: 150 DNKNVREEESRVH------KNTEDRGDAEIKERSTSRDRKQKEELKEDRK---PREKDKD 200
D++ V++E R K +++ + E KER +R++ +L+ +++ RE+D++
Sbjct: 1231 DSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRE 1290
Query: 201 KEKAKENG-GNRHREGERERAKARARPDNERQKDRGNRERDRDS 243
+E+ +E G+R R+ ER+R + R R + R R +R R R +
Sbjct: 1291 RERERERDRGDRDRDRERDRERGRER--DRRDTKRHSRSRSRST 1332
Score = 45.4 bits (106), Expect = 2e-04
Identities = 30/113 (26%), Positives = 58/113 (51%), Gaps = 9/113 (7%)
Query: 136 VKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPR 195
V+ A R++E + + +E+E K E + E + R R+++++ + DR+ R
Sbjct: 1235 VQKEAERAERAKEREKRR-KEQEEEEQKEREKEAERE-RNRQLEREKRREHSRERDRE-R 1291
Query: 196 EKDKDKEKAKENGGNRHREGERERAKARARPD---NERQKDRGNRERDRDSER 245
E+++++++ +R RE +RER + R R D + R + R RDR R
Sbjct: 1292 ERERERDRGDR---DRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 43.9 bits (102), Expect = 4e-04
Identities = 83/434 (19%), Positives = 169/434 (38%), Gaps = 55/434 (12%)
Query: 118 KLSSDDAVRRVLAGEKGEVKGRASLTSR-SQELDNKNVREEESRVH------------KN 164
++S + +++ L ++ ++ R +R + EL+ + E+ +H ++
Sbjct: 130 EMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASLLPPDFQS 189
Query: 165 TEDRGDAEIKERSTSRDRKQKEEL--KEDRKPREKDKDKEKAKENGGNRHREGERERAKA 222
+ +R + E+ S + EE +D KPR+ ++ + ++ + EG +
Sbjct: 190 SLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPA--- 246
Query: 223 RARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRV 282
+ E ++ +R ++R +TE + E +E+E D + E D + K R+ +
Sbjct: 247 ----EEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEE-DDEEEEGDDEGQKSREAPIL 301
Query: 283 KNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTT 342
K + + E E+ S E G F S+ E R +
Sbjct: 302 KEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEM 361
Query: 343 KTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPE------------IPNELSSNIR 390
KT+ + E S+ ++KS+ P P +P + +S
Sbjct: 362 KTTSPLEEEEREIKSSQGL--------KEKSKSPSPPRLTEDRKKASLVALPEQTASEEE 413
Query: 391 RIP----RPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSD---NEEDDQF 443
P + S+ P P++ ++ +E ++ +S T++ + ++ Q
Sbjct: 414 TPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELLVSQHTVQL 473
Query: 444 VVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKERSLFE 503
V +P LS S+ + + E EE LV+K T DY Q+ +P E +RS
Sbjct: 474 VGGLSP-LSSPSDTKAESPAEKVPEESVLPLVQK--STLADY-SAQKDLEP-ESDRSAQP 528
Query: 504 SAWKKEKDIVSKEI 517
K E+ ++K I
Sbjct: 529 LPLKIEELALAKGI 542
Score = 43.5 bits (101), Expect = 6e-04
Identities = 82/404 (20%), Positives = 142/404 (35%), Gaps = 39/404 (9%)
Query: 216 ERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRD--RERDRDK 273
E RA P + R K + R S + R + R R + RD
Sbjct: 556 EGRRASHTLLPSH-RLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDV 614
Query: 274 GKDR----DRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAE-T 328
+ R R R K G S R ++R + ++S K LS G +DS T
Sbjct: 615 AQARTHANPRGRPKMGSRSTSESRSRSRSRSR-----SASSNSRKSLSPGVSRDSSTSYT 669
Query: 329 ETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKS-EVPETPEIPNELSS 387
ET+ + + T + + E STS + A Q +S E T + E S
Sbjct: 670 ETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVTQRLQPERGS 729
Query: 388 NIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESH-----NSDNEEDDQ 442
P+ A A P Q Q + + + + E S+N ++
Sbjct: 730 -----PKKCEAEEAEPPAATQPQTSETQTSHLPESERIHHTVEEKEEVTMDTSENRPEND 784
Query: 443 FVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSP---------K 493
P ++S + +EE+K L K + P +
Sbjct: 785 VPEPPMPIADQVSNDDRPEGSVEDEEKKESSLPKSFKRKISVVSATKGVPAGNSDTEGGQ 844
Query: 494 PGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPLGKIMDYIQEDVDAMQNELQ 553
PG K R +A ++K +S E L++ I + K ++D +D ++E +
Sbjct: 845 PGRKRRWGASTATTQKKPSISITTESLKSLIPDI-KPLAGQEAVVDLHADDSRISEDETE 903
Query: 554 MWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQQDK 597
+ ++ H + L +I + + AE E Q +++++K
Sbjct: 904 R-NGDDGTHDKGL----KICRTVTQVVPAEGQENGQREEEEEEK 942
Score = 31.2 bits (69), Expect = 3.0
Identities = 48/254 (18%), Positives = 86/254 (33%), Gaps = 33/254 (12%)
Query: 164 NTEDRGDAEIKERSTSRDRKQKEELKEDRKP-REKDKDKEKAKENG--------GNRHRE 214
++ R + S SR R P R K +D +A+ + G+R
Sbjct: 576 SSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTS 635
Query: 215 GERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKE------KERLRDRDRE 268
R R+++R+R + + + RDS + G+E + +E
Sbjct: 636 ESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEPKE 695
Query: 269 RDRDKGKDRDRRRVKNGEHSWDLDREKN-REHDKPEKKSASSGEMSKKLSDGTFKDSKAE 327
R RR+ E + EK+ + +PE+ S E + + +E
Sbjct: 696 RTSTSSSSVQARRLSQPESA-----EKHVTQRLQPERGSPKKCEAEEAEPPAATQPQTSE 750
Query: 328 TET---------EISTRASKSLTTKTSKRRSKNSVEGDSTSDAE---GDAGPAGQDKSEV 375
T+T + + +T TS+ R +N V A+ D P G + E
Sbjct: 751 TQTSHLPESERIHHTVEEKEEVTMDTSENRPENDVPEPPMPIADQVSNDDRPEGSVEDEE 810
Query: 376 PETPEIPNELSSNI 389
+ +P I
Sbjct: 811 KKESSLPKSFKRKI 824
Score = 30.4 bits (67), Expect = 5.1
Identities = 27/112 (24%), Positives = 43/112 (38%), Gaps = 6/112 (5%)
Query: 109 QIIGKCCLNKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDR 168
QI+ K + + +R E+ E K R R + N+ + E+ R H DR
Sbjct: 1233 QIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERER---NRQLEREKRREHSRERDR 1289
Query: 169 GDAEIKERSTS---RDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGER 217
+ER RDR++ E +R R+ + + R R G R
Sbjct: 1290 ERERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 76.6 bits (187), Expect = 6e-14
Identities = 55/224 (24%), Positives = 108/224 (48%), Gaps = 24/224 (10%)
Query: 144 SRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEK 203
S + E K EEE R+ + + ++K +K+ E+ + RE++K++E+
Sbjct: 456 SAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKERER 515
Query: 204 AKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLR 263
KE +E E+ER K ER+KDR ER ++ E++ E E++ + EKER +
Sbjct: 516 EKE----LEKEQEQEREK-------EREKDR---ERQQEKEKELEKEQEKQREMEKERKQ 561
Query: 264 DRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKD 323
++++E +R K K+++ +++K E +L++E+ + +K E + + M +
Sbjct: 562 EKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVE--------- 612
Query: 324 SKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGP 367
K E+E + T + S R K + ++ E + P
Sbjct: 613 -KQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQP 655
Score = 62.4 bits (150), Expect = 1e-09
Identities = 58/232 (25%), Positives = 101/232 (43%), Gaps = 18/232 (7%)
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
R+ E E+A++ R E +R A A + G E+ E +E ER
Sbjct: 450 RQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERER 509
Query: 252 KSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDK-----PEKKS 306
+ E +EKE +++++ER++++ KDR+R++ K E + ++EK RE +K EK+
Sbjct: 510 EKEREREKELEKEQEQEREKEREKDRERQQEK--EKELEKEQEKQREMEKERKQEKEKEL 567
Query: 307 ASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAG 366
E K+L ++ + E E E K + + E +++ + E +
Sbjct: 568 ERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPV 627
Query: 367 PAGQD--KSEVPETPEIPNELSSNIRRIPRPG--------SARPAPPRVKRQ 408
QD +SE TP + +E PRP + PPR +RQ
Sbjct: 628 FTRQDSNRSEKEATP-VVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQ 678
Score = 53.1 bits (126), Expect = 7e-07
Identities = 35/140 (25%), Positives = 65/140 (46%), Gaps = 3/140 (2%)
Query: 211 RHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERD 270
R ++ E A RAR E ++ R +R K + + G EK+ + RER+
Sbjct: 449 RRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERE 508
Query: 271 RDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETET 330
R+K ++R++ K E + +REK+RE + ++K + ++ + K+ K E E
Sbjct: 509 REKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREME---KERKQEKEK 565
Query: 331 EISTRASKSLTTKTSKRRSK 350
E+ + K + K + K
Sbjct: 566 ELERQKEKEKELQKMKEQEK 585
Score = 48.1 bits (113), Expect = 2e-05
Identities = 41/160 (25%), Positives = 71/160 (44%), Gaps = 15/160 (9%)
Query: 115 CLNKLSSDDAVRRVL----AGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGD 170
C KL D +L + E+ + R R +EL+ + +E E K+ E + +
Sbjct: 481 CAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQE 540
Query: 171 AEI-------KERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKAR 223
E K+R ++RKQ++E KE + +EK+K+ +K KE E ERE+ + +
Sbjct: 541 KEKELEKEQEKQREMEKERKQEKE-KELERQKEKEKELQKMKEQEKECELEKEREKLEEK 599
Query: 224 ARPDNERQKDRGNRERDRDSERKKET---ERKSEGGKEKE 260
P + ++ +S K+E R+ EKE
Sbjct: 600 IEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKE 639
Score = 43.9 bits (102), Expect = 4e-04
Identities = 71/374 (18%), Positives = 143/374 (38%), Gaps = 41/374 (10%)
Query: 226 PDNERQKDRGNRERDRDSERKKETERKS--EGGKEKERLRDRDRERDRDKGKDRDRRRVK 283
P + + ++G R R E ER S + KE + + + + D+G + V
Sbjct: 268 PPSLSETNKGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEV- 326
Query: 284 NGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTK 343
+++ L+ + E K +S + K S+ ++K ET+ +T++S + +
Sbjct: 327 --DYTEQLNFSDDDEQGSNSPKENNSEDQGSKASENN--ENKKETDEVSNTKSSSQIPAQ 382
Query: 344 TSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPP 403
S + +G S + G + S +P P++ + R PG P P
Sbjct: 383 PSVAKVPYG-KGPSFNQERGTS-------SHLPPPPKLLAQQHPPPDRQAVPGRPGPFPS 434
Query: 404 RVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNEEDDQF-------------------- 443
+ + D E + R + +S + + EE+ +
Sbjct: 435 KQQVADEDEIWKQRRRQQSE-ISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLG 493
Query: 444 VVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKERSLFE 503
++E P E+ E E E E+E + ++ E +KD E+ Q+ K EKE+
Sbjct: 494 ILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQR 553
Query: 504 SAWKKEKDIVSKEIEKLRTSIQTLCK-----SALPLGKIMDYIQEDVDAMQNELQMWHSE 558
K+ K KE+E+ + + L K L K + ++E ++ + L+ +
Sbjct: 554 EMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEK 613
Query: 559 NRQHAEALQQEQRI 572
++E+ +
Sbjct: 614 QESENSCNKEEEPV 627
Score = 38.1 bits (87), Expect = 0.024
Identities = 26/127 (20%), Positives = 51/127 (40%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
EK K R + +EL+ + ++ E + E + E ++ +K KE+ KE
Sbjct: 528 EKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKEC 587
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
+E++K +EK + N E++ ++ + E R + R E
Sbjct: 588 ELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHET 647
Query: 252 KSEGGKE 258
+ E G +
Sbjct: 648 EPESGSQ 654
Score = 31.6 bits (70), Expect = 2.3
Identities = 35/163 (21%), Positives = 67/163 (41%), Gaps = 26/163 (15%)
Query: 146 SQELDNKNVREEESRVHKNTEDRGDAEIK-ERSTSRDRKQKEELKEDRKPREKDKDKEKA 204
SQ ++V + K E R + + TSR KE ++ +P EK K +
Sbjct: 917 SQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIE---RPEEKPKKEGFI 973
Query: 205 KENGGNRHREGERERAKAR--ARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262
+ + G + + + +++ R RP + R+++ +R R KK R
Sbjct: 974 RSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLR----------- 1022
Query: 263 RDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
D ++R++R+ K GE + + + + +K EKK
Sbjct: 1023 ---------DMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKK 1056
Score = 31.6 bits (70), Expect = 2.3
Identities = 60/273 (21%), Positives = 100/273 (36%), Gaps = 51/273 (18%)
Query: 134 GEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQK------EE 187
G ++ R +RS+ D + V + R + +E D+EI E ++ +D K EE
Sbjct: 1234 GPLRQREESETRSESSDFEVVPKR--RRQRGSETDTDSEIHESASDKDSLSKGKLPKREE 1291
Query: 188 LKEDRKP-------------------------REKDKDK-------EKAKENGGNRHREG 215
E++KP R+ DK K E + G R G
Sbjct: 1292 RPENKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRG 1351
Query: 216 ERERAKARARPDN-ERQKDRGNRERDRDSERKKETERKSEGGKEK-----ERLRDRDRER 269
R+ +RP R R N+ R SE K + + E+ R ER
Sbjct: 1352 GRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFER 1411
Query: 270 DRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAE-- 327
D ++R RR+ D R ++ + ++ S E+ ++GT + E
Sbjct: 1412 KFDPARERPRRQRPTRPPRQDKPPRFRRLRER--EAASKSNEVVAVPTNGTVNNVAQEPV 1469
Query: 328 -TETEISTRASKSLTTKTSKRRSKNSVEGDSTS 359
T +IS + L+ + S ++ E S S
Sbjct: 1470 NTLGDISGNKTPDLSNQNSSDQANEEWETASES 1502
Score = 29.6 bits (65), Expect = 8.7
Identities = 34/163 (20%), Positives = 55/163 (33%), Gaps = 17/163 (10%)
Query: 228 NERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEH 287
N+ D+ N E + SE ER+ K+ L + + + R K
Sbjct: 1485 NQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFS 1544
Query: 288 SW-DLDREKNREHDKPEKKSAS---------SGEMSKKLSDGTFKDSKAETETEISTRAS 337
S +DR+ R ++ P K + SG SK G F D A T
Sbjct: 1545 SQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGT-------TG 1597
Query: 338 KSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPE 380
L +S + G +++ G +D P+ P+
Sbjct: 1598 VDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPK 1640
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 75.9 bits (185), Expect = 1e-13
Identities = 63/212 (29%), Positives = 101/212 (47%), Gaps = 21/212 (9%)
Query: 152 KNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKE-ELKEDRKPREKDKDKEKAKENGGN 210
+ +RE +S ++K G A ++ +S++ D K + ELK D + KA + N
Sbjct: 499 RKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQEDAN 558
Query: 211 RHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERD 270
+ R + ER+++R +ER+R+ ER+KE ER+ E K KE ++RD +D
Sbjct: 559 EIKS---------KRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKD 609
Query: 271 RDKGKDRDRRRVKNGE--HSWDLDREKNREHDKPEK------KSASSGEMSKKLSDGTFK 322
++KGK D R+ K E ++ +K +E K K +SA + K K
Sbjct: 610 KEKGKHDDGRK-KEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEK 668
Query: 323 DSKAETETEISTRASKSLTTKTSKRRSKNSVE 354
SKAE E ++ R K L K K K + E
Sbjct: 669 KSKAELE-DLRQRL-KDLEDKEKKENKKMADE 698
Score = 60.1 bits (144), Expect = 6e-09
Identities = 46/159 (28%), Positives = 80/159 (50%), Gaps = 15/159 (9%)
Query: 129 LAGEKGEVKGRASLTSRSQELDN--KNVREEESRVHKNTEDRGDAEIKERSTSRDR-KQK 185
L + ++ ++S + SQE N K+ R+EE R + E + E +ER ++R ++K
Sbjct: 536 LKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERE-REREKEKEREREK 594
Query: 186 EELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKD--------RGNR 237
++LKE K R+ KDKEK K + G + ++ K + E QK+ R
Sbjct: 595 QKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAP 654
Query: 238 ERDRDSERKKETERKSEGGKE--KERLRD-RDRERDRDK 273
+ RD + E+KS+ E ++RL+D D+E+ +K
Sbjct: 655 KEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENK 693
Score = 58.5 bits (140), Expect = 2e-08
Identities = 80/387 (20%), Positives = 161/387 (41%), Gaps = 29/387 (7%)
Query: 186 EELKEDRKPREKDKDKEKAKENGGNR--HREGERERAK---ARARPDNERQKDRGNRERD 240
E L+ RK RE D K + G+ + E K A +PD+E + + +
Sbjct: 493 EVLRYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKA 552
Query: 241 RDSERKKETERKSEGGKEKERL-RDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREH 299
+ + ++ E +E+ER ++R+RER+R+K K+R+R + K E + D K++E
Sbjct: 553 SQEDANEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEK 612
Query: 300 DKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTS 359
K + E+ K+L K +++ E ++ +S + + + E S +
Sbjct: 613 GKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKA 672
Query: 360 DAEG--DAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMD 417
+ E +DK + + IR + + +Q+ EAL +
Sbjct: 673 ELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAKQEE-EALLSE 731
Query: 418 RSGSGKTVSNV----ITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGG 473
+G+ ++ I ++D F + +SE + + + EE+E+
Sbjct: 732 MDVTGQAFEDMQEQNIRLMQQLREKDDANFKL-----MSERIKSNQIHKLLKEEKEE--- 783
Query: 474 LVKKILETKKDYE-KLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRT-SIQTLCKSA 531
L ++L K + +LQ K EKE L + EK++ LRT +++ + A
Sbjct: 784 LADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGEKEL------GLRTQALEMNKRKA 837
Query: 532 LPLGKIMDYIQEDVDAMQNELQMWHSE 558
+ ++ D ++ ++ Q +L + E
Sbjct: 838 MEAAQLADDLKAQLELAQKKLHDFQDE 864
Score = 38.9 bits (89), Expect = 0.014
Identities = 63/255 (24%), Positives = 107/255 (41%), Gaps = 34/255 (13%)
Query: 353 VEGDSTSDAEGDAGPAGQDKSEVPETPEIPN-ELSSNIRRIPRPGSARPAPPRVKRQDSM 411
+E + T A AGP ++ + + + N +L + R R R A Q +
Sbjct: 457 IEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYKR--KLREA------QSDL 508
Query: 412 EALQMDRSGSGKTVSNVITESHNSDNEE-----DDQFVVEAAPQLSEMSEIEMVTAVELE 466
++ RSGS S TE + E +D +A + S+ E+ + + E
Sbjct: 509 NKTRL-RSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEE 567
Query: 467 EEEKHGGLVKKILETKKDYEKLQ----QSPKPGEKERSLFESAWKKEKDIVSKEIEKLRT 522
E E+ ++ E +++ EK + Q K EKER +SA KEK K + +
Sbjct: 568 ERERERREKEREREREREKEKEREREKQKLKESEKER---DSAKDKEK---GKHDDGRKK 621
Query: 523 SIQTLCKSALPLGKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKA 582
+ + + + L K QE M+ L M+ S ++ + +Q A + KA
Sbjct: 622 EAEIIKQLKIELKKA----QESQKEMKLLLDMYRSAPKEQRDKVQLM-----AAEKKSKA 672
Query: 583 ELAELEQLIKDQQDK 597
EL +L Q +KD +DK
Sbjct: 673 ELEDLRQRLKDLEDK 687
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.126 0.337
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,196,284
Number of Sequences: 37866
Number of extensions: 1222732
Number of successful extensions: 30251
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 636
Number of HSP's successfully gapped in prelim test: 1084
Number of HSP's that attempted gapping in prelim test: 8310
Number of HSP's gapped (non-prelim): 8642
length of query: 625
length of database: 18,247,518
effective HSP length: 108
effective length of query: 517
effective length of database: 14,157,990
effective search space: 7319680830
effective search space used: 7319680830
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.