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Search of human proteins with 21314682
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21314682 transient receptor potential cation channel,
subfamily V, member 6 [Homo sapiens]
(725 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21314682 transient receptor potential cation channel, subfami... 1466 0.0
gi|17505200 transient receptor potential cation channel, subfami... 1071 0.0
gi|22547184 transient receptor potential cation channel, subfami... 270 3e-72
gi|21735483 transient receptor potential cation channel, subfami... 249 8e-66
gi|74315354 transient receptor potential cation channel, subfami... 242 8e-64
gi|74315352 transient receptor potential cation channel, subfami... 242 8e-64
gi|74315350 transient receptor potential cation channel, subfami... 242 8e-64
gi|74315348 transient receptor potential cation channel, subfami... 242 8e-64
gi|20127551 transient receptor potential cation channel, subfami... 225 1e-58
gi|22547180 transient receptor potential cation channel, subfami... 208 2e-53
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] 74 5e-13
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 74 5e-13
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 74 5e-13
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 74 5e-13
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens] 74 5e-13
gi|116534990 ankyrin-like protein 1 [Homo sapiens] 65 3e-10
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 65 3e-10
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 65 3e-10
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 65 3e-10
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 64 5e-10
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 59 1e-08
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 59 1e-08
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 59 1e-08
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 59 1e-08
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 59 1e-08
gi|24233530 ankyrin repeat domain 44 [Homo sapiens] 59 2e-08
gi|68131557 ankyrin repeat domain 28 [Homo sapiens] 58 3e-08
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 58 3e-08
gi|164664508 B-cell CLL/lymphoma 3 [Homo sapiens] 56 1e-07
gi|89363047 death-associated protein kinase 1 [Homo sapiens] 56 1e-07
>gi|21314682 transient receptor potential cation channel, subfamily
V, member 6 [Homo sapiens]
Length = 725
Score = 1466 bits (3796), Expect = 0.0
Identities = 725/725 (100%), Positives = 725/725 (100%)
Query: 1 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 60
MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA
Sbjct: 1 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 60
Query: 61 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120
LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA
Sbjct: 61 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120
Query: 121 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 180
LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR
Sbjct: 121 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 180
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 240
LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG
Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 240
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 300
LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK
Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 300
Query: 301 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 360
KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT
Sbjct: 301 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 360
Query: 361 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 420
SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI
Sbjct: 361 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 420
Query: 421 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 480
LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI
Sbjct: 421 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 480
Query: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 540
MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI
Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 540
Query: 541 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 600
IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT
Sbjct: 541 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 600
Query: 601 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD 660
TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD
Sbjct: 601 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD 660
Query: 661 KDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLEDGES 720
KDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLEDGES
Sbjct: 661 KDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLEDGES 720
Query: 721 WEYQI 725
WEYQI
Sbjct: 721 WEYQI 725
>gi|17505200 transient receptor potential cation channel, subfamily
V, member 5 [Homo sapiens]
Length = 729
Score = 1072 bits (2771), Expect = 0.0
Identities = 547/729 (75%), Positives = 607/729 (83%), Gaps = 15/729 (2%)
Query: 1 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 60
MG LPK +G L + R + W Q D+ ++LQQKRI ESPLL A+K+ND+
Sbjct: 1 MGGFLPKAEGPGSQLQKLLPSFLVREQDWDQHLDKLHMLQQKRILESPLLRASKENDLSV 60
Query: 61 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120
L +LL C V QRGA+GETALHIAALYDNLEAA+VLMEAAPELVFEP T E + GQTA
Sbjct: 61 LRQLLLDCTCDVRQRGALGETALHIAALYDNLEAALVLMEAAPELVFEPTTCEAFAGQTA 120
Query: 121 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 180
LHIAVVNQN+NLVRALL RRASVSARATGTAFRRSP NLIYFGEHPLSFAACVNSEEIVR
Sbjct: 121 LHIAVVNQNVNLVRALLTRRASVSARATGTAFRRSPRNLIYFGEHPLSFAACVNSEEIVR 180
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 240
LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD HGDHLQPLDLVPNHQG
Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGHGDHLQPLDLVPNHQG 240
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 300
LTPFKLAGVEGNTVMFQHLMQKR+H QWTYGPLTS LYDLTEIDS G+E S LEL++++
Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRRHIQWTYGPLTSILYDLTEIDSWGEELSFLELVVSSD 300
Query: 301 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 360
KREARQIL+QTPVKELVS KW +YGRPYFC+L A+YLLY+ICFT CC+YRPLK R NRT
Sbjct: 301 KREARQILEQTPVKELVSFKWNKYGRPYFCILAALYLLYMICFTTCCVYRPLKFRGGNRT 360
Query: 361 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 420
RD T+LQQKLLQEAY T +D IRLVGELV+++GA+IILL+E+PDIFR+G +R+FG+TI
Sbjct: 361 HSRDITILQQKLLQEAYETREDIIRLVGELVSIVGAVIILLLEIPDIFRVGASRYFGKTI 420
Query: 421 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 480
LGGPFHV+IITYA +VLVTMVMRL + +GEVVPMSFALVLGWC+VMYF RGFQMLGPFTI
Sbjct: 421 LGGPFHVIIITYASLVLVTMVMRLTNTNGEVVPMSFALVLGWCSVMYFTRGFQMLGPFTI 480
Query: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 540
MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDP LG FYDYPMALF+TFELFLT+
Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPTSLGQFYDYPMALFTTFELFLTV 540
Query: 541 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 600
ID PANY+VDLPFM+SI AFAIIATLLMLNL IAMMGDTHWRVA ERDELWRAQ+VAT
Sbjct: 541 IDAPANYDVDLPFMFSIVNFAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT 600
Query: 601 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD 660
TVMLERKLPRCLWPRSGICG E+GLGDRWFLRVE+ D N R+ RY + F ED
Sbjct: 601 TVMLERKLPRCLWPRSGICGCEFGLGDRWFLRVENHNDQNPLRVLRYVEVFKNSDKEDDQ 660
Query: 661 KDSVEK----LELGCPFSPHLSLPMPSVSRSTSRSSAN--WERLRQGTLRRDLRGIINRG 714
+ EK E G L+LP S+SR+ S+SS++ WE LRQ TL G +N G
Sbjct: 661 EHPSEKQPSGAESGTLARASLALPTSSLSRTASQSSSHRGWEILRQNTL-----GHLNLG 715
Query: 715 LE----DGE 719
L DGE
Sbjct: 716 LNLSEGDGE 724
>gi|22547184 transient receptor potential cation channel, subfamily
V, member 4 isoform a [Homo sapiens]
Length = 871
Score = 270 bits (691), Expect = 3e-72
Identities = 183/546 (33%), Positives = 278/546 (50%), Gaps = 61/546 (11%)
Query: 104 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIYF 162
E + P Y GQTALHIA+ + + V L+A+ A V A+A G F+ + YF
Sbjct: 225 EFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYF 284
Query: 163 GEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQ 214
GE PLS AAC N IV L E+ AD+R QDS GNTVLH L+ + N F +
Sbjct: 285 GELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTK 344
Query: 215 MYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK-----------R 263
MY+LLL L+ V N+ GL+P +A G +FQH++++ R
Sbjct: 345 MYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDEDTRHLSR 404
Query: 264 KHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWK 322
K W YGP+ S+LYDL+ +D+ G+E S+LE+++ K E R ++L P+ EL+ KW+
Sbjct: 405 KFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILVYNSKIENRHEMLAVEPINELLRDKWR 464
Query: 323 RYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKD 382
++G F + YL ++ FT+ Y+PL+ T P Y T D
Sbjct: 465 KFGAVSFYINVVSYLCAMVIFTLTAYYQPLEG-----TPPYP------------YRTTVD 507
Query: 383 DIRLVGELVTVIGAIIILLVEVPDIFRM---GVTRFFGQTILGGPFHVLIITYAFMVLVT 439
+RL GE++T+ ++ + D+F GV F + G F +L Y+ +V+V+
Sbjct: 508 YLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLF----IDGSFQLLYFIYSVLVIVS 563
Query: 440 MVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAV 499
+ L + M FALVLGW N +YF RG ++ G ++IMIQK++F DL RF + +
Sbjct: 564 AALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLL 623
Query: 500 VILGFASAFYIIFQ-------TEDPEELGHFYDYPMA----LFSTF--ELF-LTIIDGPA 545
++G+ASA + + + YP FSTF +LF LTI G
Sbjct: 624 FMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDL 683
Query: 546 NY--NVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVM 603
+ P ++ I + I+ +L+LN+LIA+MG+T +V+ E +W+ Q T +
Sbjct: 684 EMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATTILD 743
Query: 604 LERKLP 609
+ER P
Sbjct: 744 IERSFP 749
>gi|21735483 transient receptor potential cation channel, subfamily
V, member 3 [Homo sapiens]
Length = 790
Score = 249 bits (635), Expect = 8e-66
Identities = 160/527 (30%), Positives = 270/527 (51%), Gaps = 43/527 (8%)
Query: 111 TSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIYFGEHPLSF 169
T E YEGQTAL+IA+ + ++ L+A A V+A A G F + YFGE PL+
Sbjct: 209 TEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLAL 268
Query: 170 AACVNSEEIVRLLIEHG-ADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYD 223
AAC N EIV+LL+EH DI ++DS GN +LH L+ + F +MY+++L
Sbjct: 269 AACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRS 328
Query: 224 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK-----------RKHTQWTYGP 272
+ + L+ N+ GLTP +LA G + ++++ + RK T W YGP
Sbjct: 329 GNWE----LETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGP 384
Query: 273 LTSTLYDLTEIDSSGDEQSLLELIITTKKREARQILDQTPVKELVSLKWKRYGRPYFCML 332
++S+LYDLT +D++ D L + T ++L P+ L+ +KWK++ + F +
Sbjct: 385 VSSSLYDLTNVDTTTDNSVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLS 444
Query: 333 GAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLVGELVT 392
Y Y I T+ YR PR+ + L A ++L+G +
Sbjct: 445 FCFYFFYNITLTLVSYYR-----------PREEEAIPHPL---ALTHKMGWLQLLGRMFV 490
Query: 393 VIGAIIILLVEVPDIFRMGVTRFFGQTILGGP-FHVLIITYAFMVLVTMVMRLISASGEV 451
+I A+ I + E IF + + Q+IL FH + A +V++++ + L + +
Sbjct: 491 LIWAMCISVKEGIAIFLLRPSDL--QSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYL 548
Query: 452 VPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYII 511
+ A+ LGW N++Y+ RGFQ +G +++MIQK+I D+++F ++ V +LGF A +
Sbjct: 549 ACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGFGVALASL 608
Query: 512 FQ--TEDPEELGHFYDYPMALFSTFELFLTIIDGPANYNVDLPFMYSITYAAFAIIATLL 569
+ +D ++ + + A+ F+L + + D N P ++ + I+ +L
Sbjct: 609 IEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVL 668
Query: 570 MLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLPRCLWPRS 616
+LN+LIA+MG+T V+ E + +WR Q T + E+ LP W RS
Sbjct: 669 LLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPE--WLRS 713
Score = 30.8 bits (68), Expect = 4.6
Identities = 36/186 (19%), Positives = 77/186 (41%), Gaps = 18/186 (9%)
Query: 46 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALH-IAALYDNLEAAMVLMEAAPE 104
E+PL LAA N + + L+++E + R + G LH + + ++ + ++ +
Sbjct: 263 ETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYD 322
Query: 105 LV------FEPMTSELYEGQTALHIAVVNQNMNLVRALLARR------ASVSARATGTAF 152
++ +E T+ +G T L +A +++ +L+R S+S + T A+
Sbjct: 323 MILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAY 382
Query: 153 RRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFA 212
+L + L+ ++ + + + + L LH L+ K FA
Sbjct: 383 GPVSSSL-----YDLTNVDTTTDNSVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFA 437
Query: 213 CQMYNL 218
M+ L
Sbjct: 438 KHMFFL 443
>gi|74315354 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 242 bits (618), Expect = 8e-64
Identities = 177/562 (31%), Positives = 274/562 (48%), Gaps = 78/562 (13%)
Query: 100 EAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNL 159
++ ELV T Y+GQTALHIA+ +NM LV L+ A V A A G F+++
Sbjct: 185 DSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRP 244
Query: 160 -IYFGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKT 210
YFGE PLS AAC N IV+ L+++ ADI A+DS+GNTVLH L+ N
Sbjct: 245 GFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTK 304
Query: 211 FACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK-------- 262
F MYN +L L+ + N +G+TP LA G + +++Q+
Sbjct: 305 FVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPECR 364
Query: 263 ---RKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELII--TTKKREARQILDQTPVKELV 317
RK T+W YGP+ S+LYDL+ ID+ ++ S+LE+I +++ +L P+ L+
Sbjct: 365 HLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETPNRHDMLLVEPLNRLL 423
Query: 318 SLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRP---LKPRTNNRTSPRDNTLLQQKLLQ 374
KW R+ + F +Y LY+I FTM YRP L P +T
Sbjct: 424 QDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTG------------- 470
Query: 375 EAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQT------ILGGPFHVL 428
D R+ GE+++V+G + F G+ F + + +L
Sbjct: 471 -------DYFRVTGEILSVLGGVYF--------FFRGIQYFLQRRPSMKTLFVDSYSEML 515
Query: 429 IITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFG 488
+ +L T+V+ V M F+L LGW N++Y+ RGFQ +G + +MI+KMI
Sbjct: 516 FFLQSLFMLATVVLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILR 575
Query: 489 DLMRFCWLMAVVILGFASAFYIIFQ-----TEDPEELGHFYDYPM---------ALFST- 533
DL RF ++ V + GF++A + + + E H + P +L+ST
Sbjct: 576 DLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTC 635
Query: 534 FELF-LTIIDGPANY--NVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERD 590
ELF TI G + N D ++ I A+ I+ +L+LN+LIA+MG+T ++A E
Sbjct: 636 LELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESK 695
Query: 591 ELWRAQIVATTVMLERKLPRCL 612
+W+ Q T + E+ +C+
Sbjct: 696 NIWKLQRAITILDTEKSFLKCM 717
>gi|74315352 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 242 bits (618), Expect = 8e-64
Identities = 177/562 (31%), Positives = 274/562 (48%), Gaps = 78/562 (13%)
Query: 100 EAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNL 159
++ ELV T Y+GQTALHIA+ +NM LV L+ A V A A G F+++
Sbjct: 185 DSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRP 244
Query: 160 -IYFGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKT 210
YFGE PLS AAC N IV+ L+++ ADI A+DS+GNTVLH L+ N
Sbjct: 245 GFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTK 304
Query: 211 FACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK-------- 262
F MYN +L L+ + N +G+TP LA G + +++Q+
Sbjct: 305 FVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPECR 364
Query: 263 ---RKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELII--TTKKREARQILDQTPVKELV 317
RK T+W YGP+ S+LYDL+ ID+ ++ S+LE+I +++ +L P+ L+
Sbjct: 365 HLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETPNRHDMLLVEPLNRLL 423
Query: 318 SLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRP---LKPRTNNRTSPRDNTLLQQKLLQ 374
KW R+ + F +Y LY+I FTM YRP L P +T
Sbjct: 424 QDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTG------------- 470
Query: 375 EAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQT------ILGGPFHVL 428
D R+ GE+++V+G + F G+ F + + +L
Sbjct: 471 -------DYFRVTGEILSVLGGVYF--------FFRGIQYFLQRRPSMKTLFVDSYSEML 515
Query: 429 IITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFG 488
+ +L T+V+ V M F+L LGW N++Y+ RGFQ +G + +MI+KMI
Sbjct: 516 FFLQSLFMLATVVLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILR 575
Query: 489 DLMRFCWLMAVVILGFASAFYIIFQ-----TEDPEELGHFYDYPM---------ALFST- 533
DL RF ++ V + GF++A + + + E H + P +L+ST
Sbjct: 576 DLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTC 635
Query: 534 FELF-LTIIDGPANY--NVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERD 590
ELF TI G + N D ++ I A+ I+ +L+LN+LIA+MG+T ++A E
Sbjct: 636 LELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESK 695
Query: 591 ELWRAQIVATTVMLERKLPRCL 612
+W+ Q T + E+ +C+
Sbjct: 696 NIWKLQRAITILDTEKSFLKCM 717
>gi|74315350 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 242 bits (618), Expect = 8e-64
Identities = 177/562 (31%), Positives = 274/562 (48%), Gaps = 78/562 (13%)
Query: 100 EAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNL 159
++ ELV T Y+GQTALHIA+ +NM LV L+ A V A A G F+++
Sbjct: 185 DSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRP 244
Query: 160 -IYFGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKT 210
YFGE PLS AAC N IV+ L+++ ADI A+DS+GNTVLH L+ N
Sbjct: 245 GFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTK 304
Query: 211 FACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK-------- 262
F MYN +L L+ + N +G+TP LA G + +++Q+
Sbjct: 305 FVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPECR 364
Query: 263 ---RKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELII--TTKKREARQILDQTPVKELV 317
RK T+W YGP+ S+LYDL+ ID+ ++ S+LE+I +++ +L P+ L+
Sbjct: 365 HLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETPNRHDMLLVEPLNRLL 423
Query: 318 SLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRP---LKPRTNNRTSPRDNTLLQQKLLQ 374
KW R+ + F +Y LY+I FTM YRP L P +T
Sbjct: 424 QDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTG------------- 470
Query: 375 EAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQT------ILGGPFHVL 428
D R+ GE+++V+G + F G+ F + + +L
Sbjct: 471 -------DYFRVTGEILSVLGGVYF--------FFRGIQYFLQRRPSMKTLFVDSYSEML 515
Query: 429 IITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFG 488
+ +L T+V+ V M F+L LGW N++Y+ RGFQ +G + +MI+KMI
Sbjct: 516 FFLQSLFMLATVVLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILR 575
Query: 489 DLMRFCWLMAVVILGFASAFYIIFQ-----TEDPEELGHFYDYPM---------ALFST- 533
DL RF ++ V + GF++A + + + E H + P +L+ST
Sbjct: 576 DLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTC 635
Query: 534 FELF-LTIIDGPANY--NVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERD 590
ELF TI G + N D ++ I A+ I+ +L+LN+LIA+MG+T ++A E
Sbjct: 636 LELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESK 695
Query: 591 ELWRAQIVATTVMLERKLPRCL 612
+W+ Q T + E+ +C+
Sbjct: 696 NIWKLQRAITILDTEKSFLKCM 717
>gi|74315348 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 242 bits (618), Expect = 8e-64
Identities = 177/562 (31%), Positives = 274/562 (48%), Gaps = 78/562 (13%)
Query: 100 EAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNL 159
++ ELV T Y+GQTALHIA+ +NM LV L+ A V A A G F+++
Sbjct: 185 DSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRP 244
Query: 160 -IYFGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKT 210
YFGE PLS AAC N IV+ L+++ ADI A+DS+GNTVLH L+ N
Sbjct: 245 GFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTK 304
Query: 211 FACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK-------- 262
F MYN +L L+ + N +G+TP LA G + +++Q+
Sbjct: 305 FVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPECR 364
Query: 263 ---RKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELII--TTKKREARQILDQTPVKELV 317
RK T+W YGP+ S+LYDL+ ID+ ++ S+LE+I +++ +L P+ L+
Sbjct: 365 HLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETPNRHDMLLVEPLNRLL 423
Query: 318 SLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRP---LKPRTNNRTSPRDNTLLQQKLLQ 374
KW R+ + F +Y LY+I FTM YRP L P +T
Sbjct: 424 QDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTG------------- 470
Query: 375 EAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQT------ILGGPFHVL 428
D R+ GE+++V+G + F G+ F + + +L
Sbjct: 471 -------DYFRVTGEILSVLGGVYF--------FFRGIQYFLQRRPSMKTLFVDSYSEML 515
Query: 429 IITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFG 488
+ +L T+V+ V M F+L LGW N++Y+ RGFQ +G + +MI+KMI
Sbjct: 516 FFLQSLFMLATVVLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILR 575
Query: 489 DLMRFCWLMAVVILGFASAFYIIFQ-----TEDPEELGHFYDYPM---------ALFST- 533
DL RF ++ V + GF++A + + + E H + P +L+ST
Sbjct: 576 DLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTC 635
Query: 534 FELF-LTIIDGPANY--NVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERD 590
ELF TI G + N D ++ I A+ I+ +L+LN+LIA+MG+T ++A E
Sbjct: 636 LELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESK 695
Query: 591 ELWRAQIVATTVMLERKLPRCL 612
+W+ Q T + E+ +C+
Sbjct: 696 NIWKLQRAITILDTEKSFLKCM 717
>gi|20127551 transient receptor potential cation channel, subfamily
V, member 2 [Homo sapiens]
Length = 764
Score = 225 bits (574), Expect = 1e-58
Identities = 184/630 (29%), Positives = 300/630 (47%), Gaps = 74/630 (11%)
Query: 61 LNKLLKYEDCKVHQRGAMGETALHIAALY--DNLEAAMVLM------EAAPE-LVFEPMT 111
L+K KY + G+ G+T L A L D + A ++ + P+ LV T
Sbjct: 98 LSKTSKYLTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCT 157
Query: 112 SELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAA 171
+ Y G +ALHIA+ +++ V+ L+ A+V ARA G F++ YFGE PLS AA
Sbjct: 158 DDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAA 217
Query: 172 CVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYD 223
C ++V L+E+ A ++A DS GNTVLH L++ N MY+ LL
Sbjct: 218 CTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQAG 277
Query: 224 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK---------RKHTQWTYGPLT 274
L+ + N Q LTP KLA EG +F+H++Q+ RK T+W YGP+
Sbjct: 278 ARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQREFSGLSHLSRKFTEWCYGPVR 337
Query: 275 STLYDLTEIDSSGDEQSLLELI-ITTKKREARQILDQTPVKELVSLKWKRYGRPYFCMLG 333
+LYDL +DS +E S+LE+I K +++ P+ +L+ KW P F +
Sbjct: 338 VSLYDLASVDSC-EENSVLEIIAFHCKSPHRHRMVVLEPLNKLLQAKWDLL-IPKFFLNF 395
Query: 334 AIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTV 393
L+Y+ FT ++P + + +P + +L L G ++ +
Sbjct: 396 LCNLIYMFIFTAVAYHQPTLKK---QAAPHLKAEVGNSML------------LTGHILIL 440
Query: 394 IGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLISASGEVVP 453
+G I +L+ ++ +R V F + + F +L + A + +V+ V+ ++ +
Sbjct: 441 LGGIYLLVGQLWYFWRRHV--FIWISFIDSYFEILFLFQALLTVVSQVLCFLAIEWYLPL 498
Query: 454 MSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQ 513
+ ALVLGW N++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A + Q
Sbjct: 499 LVSALVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLIYLVFLFGFAVALVSLSQ 558
Query: 514 -------------------TEDPEELGHFYDYPMALFSTFELF-LTIIDGPANYNVDLPF 553
E E+ G+ Y L ++ ELF TI G + L F
Sbjct: 559 EAWRPEAPTGPNATESVQPMEGQEDEGNGAQYRGILEASLELFKFTIGMGELAFQEQLHF 618
Query: 554 --MYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLPRC 611
M + A+ ++ +L+LN+LIA+M +T VA + +W+ Q + + +E C
Sbjct: 619 RGMVLLLLLAYVLLTYILLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMENGYWWC 678
Query: 612 -LWPRSGI-----CGREYGLGDRWFLRVED 635
R+G+ + +RW RVE+
Sbjct: 679 RKKQRAGVMLTVGTKPDGSPDERWCFRVEE 708
>gi|22547180 transient receptor potential cation channel, subfamily
V, member 4 isoform b [Homo sapiens]
Length = 811
Score = 208 bits (529), Expect = 2e-53
Identities = 161/534 (30%), Positives = 241/534 (45%), Gaps = 97/534 (18%)
Query: 104 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIYF 162
E + P Y GQTALHIA+ + + V L+A+ A V A+A G F+ + YF
Sbjct: 225 EFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYF 284
Query: 163 GEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQ 214
GE PLS AAC N IV L E+ AD+R QDS GNTVLH L+ + N F +
Sbjct: 285 GELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTK 344
Query: 215 MYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLT 274
MY+LLL L+ V N+ GL+P +A G
Sbjct: 345 MYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTG----------------------- 381
Query: 275 STLYDLTEIDSSGDEQSLLELIITTKKREARQILDQTPVKELVSLKWKRYGRPYFCMLGA 334
K ++L P+ EL+ KW+++G F +
Sbjct: 382 -------------------------KIGNRHEMLAVEPINELLRDKWRKFGAVSFYINVV 416
Query: 335 IYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVI 394
YL ++ FT+ Y+PL+ T P Y T D +RL GE++T+
Sbjct: 417 SYLCAMVIFTLTAYYQPLEG-----TPPYP------------YRTTVDYLRLAGEVITLF 459
Query: 395 GAIIILLVEVPDIFRM---GVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLISASGEV 451
++ + D+F GV F + G F +L Y+ +V+V+ + L +
Sbjct: 460 TGVLFFFTNIKDLFMKKCPGVNSLF----IDGSFQLLYFIYSVLVIVSAALYLAGIEAYL 515
Query: 452 VPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYII 511
M FALVLGW N +YF RG ++ G ++IMIQK++F DL RF + + ++G+ASA +
Sbjct: 516 AVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSL 575
Query: 512 FQ-------TEDPEELGHFYDYPMA----LFSTF--ELF-LTIIDGPANY--NVDLPFMY 555
+ + YP FSTF +LF LTI G + P ++
Sbjct: 576 LNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDLEMLSSTKYPVVF 635
Query: 556 SITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLP 609
I + I+ +L+LN+LIA+MG+T +V+ E +W+ Q T + +ER P
Sbjct: 636 IILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATTILDIERSFP 689
>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
Length = 1897
Score = 73.9 bits (180), Expect = 5e-13
Identities = 68/233 (29%), Positives = 106/233 (45%), Gaps = 38/233 (16%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME--AAPE 104
+PL +AA++ V+ + LL+ E + G T LH+AA Y + A +L+E A P
Sbjct: 538 TPLHIAAREGHVETVLALLEKEASQACMT-KKGFTPLHVAAKYGKVRVAELLLERDAHPN 596
Query: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164
+ G T LH+AV + N+++V+ LL R SP + + G
Sbjct: 597 AAGK-------NGLTPLHVAVHHNNLDIVKLLLPRGG-------------SPHSPAWNGY 636
Query: 165 HPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDR 224
PL AA N E+ R L+++G A+ G T LH+ + + +M LLLS
Sbjct: 637 TPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGH----AEMVALLLSKQA 692
Query: 225 HGDHLQPLDLVPNHQGLTPFKLAGVEGNT----VMFQHLMQKRKHTQWTYGPL 273
+G+ + N GLTP L EG+ V+ +H + T+ Y PL
Sbjct: 693 NGN-------LGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPL 738
Score = 60.5 bits (145), Expect = 5e-09
Identities = 56/190 (29%), Positives = 80/190 (42%), Gaps = 23/190 (12%)
Query: 49 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 108
L +AA+++D + LL+ D G T LHIAA Y+NL A +L+ + F
Sbjct: 210 LHIAARNDDTRTAAVLLQ-NDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 268
Query: 109 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 168
P G T LHIA N+ +VR LL R A + + PL
Sbjct: 269 PQ-----NGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDEL-------------TPLH 310
Query: 169 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDH 228
AA I +L++HGA I+A+ G + +H+ + LLL YD D
Sbjct: 311 CAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDH----LDCVRLLLQYDAEIDD 366
Query: 229 LQPLDLVPNH 238
+ L P H
Sbjct: 367 ITLDHLTPLH 376
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/155 (30%), Positives = 70/155 (45%), Gaps = 23/155 (14%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A + + L+ Y +G + ALHIAA D+ A VL++ P
Sbjct: 179 TPLAVALQQGHENVVAHLINYGT-----KGKVRLPALHIAARNDDTRTAAVLLQNDPNPD 233
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
T G T LHIA +N+N+ + LL R ASV+ +P N G P
Sbjct: 234 VLSKT-----GFTPLHIAAHYENLNVAQLLLNRGASVNF---------TPQN----GITP 275
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
L A+ + +VRLL++ GA I + T LH
Sbjct: 276 LHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLH 310
Score = 48.1 bits (113), Expect = 3e-05
Identities = 42/156 (26%), Positives = 71/156 (45%), Gaps = 19/156 (12%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A K N V+ + LLK + G T LH+A+ +L L++
Sbjct: 406 TPLHIACKKNHVRVMELLLK-TGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS-- 462
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P S + + +T LH+A + + + LL +A V+A+A + P
Sbjct: 463 --PNVSNV-KVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD-------------QTP 506
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
L AA + +V+LL+E+ A+ + G+T LHI
Sbjct: 507 LHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHI 542
Score = 48.1 bits (113), Expect = 3e-05
Identities = 45/178 (25%), Positives = 77/178 (43%), Gaps = 32/178 (17%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A N++ + KLL H G T LHIAA + +E A L++
Sbjct: 604 TPLHVAVHHNNLDIV-KLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA- 661
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIY----- 161
+E +G T LH+A + +V LL+++A+ + G +P +L+
Sbjct: 662 ----NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNL---GNKSGLTPLHLVAQEGHV 714
Query: 162 ------------------FGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
G PL A+ + ++V+ L++H AD+ A+ LG + LH
Sbjct: 715 PVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLH 772
Score = 47.4 bits (111), Expect = 5e-05
Identities = 66/292 (22%), Positives = 114/292 (39%), Gaps = 74/292 (25%)
Query: 24 QRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDV-QALNKLLKYEDCKV-HQRGAMGET 81
++ ES + R+ ++K + L AA+ ++ +AL+ L D +Q G G
Sbjct: 24 EKEESNRKRRNRSRDRKKKADAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNG-- 81
Query: 82 ALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRA 141
LH+A+ +++ + L+ E++ E T + G TALHIA + +VR L+ A
Sbjct: 82 -LHLASKEGHVKMVVELLHK--EIILETTTKK---GNTALHIAALAGQDEVVRELVNYGA 135
Query: 142 SVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
+V+A++ G PL AA N E+V+ L+E+GA+ G T L
Sbjct: 136 NVNAQSQK-------------GFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLA 182
Query: 202 ILILQPNKTFACQMYN-------------------------LLLSYDRHGDHLQPLDLVP 236
+ + Q ++ + N +LL D + D L P
Sbjct: 183 VALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTP 242
Query: 237 NH--------------------------QGLTPFKLAGVEGNTVMFQHLMQK 262
H G+TP +A GN +M + L+ +
Sbjct: 243 LHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDR 294
Score = 46.2 bits (108), Expect = 1e-04
Identities = 51/184 (27%), Positives = 73/184 (39%), Gaps = 42/184 (22%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE-- 104
+PL +AAK N V+ LL+Y + G T LH+AA + E +L+
Sbjct: 637 TPLHIAAKQNQVEVARSLLQYGG-SANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGN 695
Query: 105 -----------LVFE----PMTSELYE-----------GQTALHIAVVNQNMNLVRALLA 138
LV + P+ L + G T LH+A N+ LV+ LL
Sbjct: 696 LGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQ 755
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
+A V+A+ G PL AA +IV LL+++GA S G T
Sbjct: 756 HQADVNAKTK-------------LGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 802
Query: 199 VLHI 202
L I
Sbjct: 803 PLAI 806
Score = 41.6 bits (96), Expect = 0.003
Identities = 56/236 (23%), Positives = 93/236 (39%), Gaps = 37/236 (15%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
SP+ +AA+ + + + LL+Y D ++ T LH+AA + A VL++ +
Sbjct: 340 SPIHMAAQGDHLDCVRLLLQY-DAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAK-- 396
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARA--------TGTAFRRSPC- 157
S G T LHIA ++ ++ LL AS+ A + P
Sbjct: 397 ---PNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIV 453
Query: 158 -NLIYFG----------EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQ 206
NL+ G E PL AA E+ + L+++ A + A+ T LH
Sbjct: 454 KNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAA-- 511
Query: 207 PNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
+ M LLL + + + + G TP +A EG+ L++K
Sbjct: 512 --RIGHTNMVKLLLENNANPN-------LATTAGHTPLHIAAREGHVETVLALLEK 558
>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
Length = 1881
Score = 73.9 bits (180), Expect = 5e-13
Identities = 68/233 (29%), Positives = 106/233 (45%), Gaps = 38/233 (16%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME--AAPE 104
+PL +AA++ V+ + LL+ E + G T LH+AA Y + A +L+E A P
Sbjct: 505 TPLHIAAREGHVETVLALLEKEASQACMT-KKGFTPLHVAAKYGKVRVAELLLERDAHPN 563
Query: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164
+ G T LH+AV + N+++V+ LL R SP + + G
Sbjct: 564 AAGK-------NGLTPLHVAVHHNNLDIVKLLLPRGG-------------SPHSPAWNGY 603
Query: 165 HPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDR 224
PL AA N E+ R L+++G A+ G T LH+ + + +M LLLS
Sbjct: 604 TPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGH----AEMVALLLSKQA 659
Query: 225 HGDHLQPLDLVPNHQGLTPFKLAGVEGNT----VMFQHLMQKRKHTQWTYGPL 273
+G+ + N GLTP L EG+ V+ +H + T+ Y PL
Sbjct: 660 NGN-------LGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPL 705
Score = 60.5 bits (145), Expect = 5e-09
Identities = 56/190 (29%), Positives = 80/190 (42%), Gaps = 23/190 (12%)
Query: 49 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 108
L +AA+++D + LL+ D G T LHIAA Y+NL A +L+ + F
Sbjct: 177 LHIAARNDDTRTAAVLLQ-NDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 109 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 168
P G T LHIA N+ +VR LL R A + + PL
Sbjct: 236 PQ-----NGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDEL-------------TPLH 277
Query: 169 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDH 228
AA I +L++HGA I+A+ G + +H+ + LLL YD D
Sbjct: 278 CAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDH----LDCVRLLLQYDAEIDD 333
Query: 229 LQPLDLVPNH 238
+ L P H
Sbjct: 334 ITLDHLTPLH 343
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/155 (30%), Positives = 70/155 (45%), Gaps = 23/155 (14%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A + + L+ Y +G + ALHIAA D+ A VL++ P
Sbjct: 146 TPLAVALQQGHENVVAHLINYGT-----KGKVRLPALHIAARNDDTRTAAVLLQNDPNPD 200
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
T G T LHIA +N+N+ + LL R ASV+ +P N G P
Sbjct: 201 VLSKT-----GFTPLHIAAHYENLNVAQLLLNRGASVNF---------TPQN----GITP 242
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
L A+ + +VRLL++ GA I + T LH
Sbjct: 243 LHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLH 277
Score = 48.1 bits (113), Expect = 3e-05
Identities = 42/156 (26%), Positives = 71/156 (45%), Gaps = 19/156 (12%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A K N V+ + LLK + G T LH+A+ +L L++
Sbjct: 373 TPLHIACKKNHVRVMELLLK-TGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS-- 429
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P S + + +T LH+A + + + LL +A V+A+A + P
Sbjct: 430 --PNVSNV-KVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD-------------QTP 473
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
L AA + +V+LL+E+ A+ + G+T LHI
Sbjct: 474 LHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHI 509
Score = 48.1 bits (113), Expect = 3e-05
Identities = 45/178 (25%), Positives = 77/178 (43%), Gaps = 32/178 (17%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A N++ + KLL H G T LHIAA + +E A L++
Sbjct: 571 TPLHVAVHHNNLDIV-KLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA- 628
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIY----- 161
+E +G T LH+A + +V LL+++A+ + G +P +L+
Sbjct: 629 ----NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNL---GNKSGLTPLHLVAQEGHV 681
Query: 162 ------------------FGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
G PL A+ + ++V+ L++H AD+ A+ LG + LH
Sbjct: 682 PVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLH 739
Score = 46.2 bits (108), Expect = 1e-04
Identities = 51/184 (27%), Positives = 73/184 (39%), Gaps = 42/184 (22%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE-- 104
+PL +AAK N V+ LL+Y + G T LH+AA + E +L+
Sbjct: 604 TPLHIAAKQNQVEVARSLLQYGG-SANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGN 662
Query: 105 -----------LVFE----PMTSELYE-----------GQTALHIAVVNQNMNLVRALLA 138
LV + P+ L + G T LH+A N+ LV+ LL
Sbjct: 663 LGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQ 722
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
+A V+A+ G PL AA +IV LL+++GA S G T
Sbjct: 723 HQADVNAKTK-------------LGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Query: 199 VLHI 202
L I
Sbjct: 770 PLAI 773
Score = 45.1 bits (105), Expect = 2e-04
Identities = 53/235 (22%), Positives = 88/235 (37%), Gaps = 69/235 (29%)
Query: 79 GETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLA 138
G LH+A+ +++ + L+ E++ E T + G TALHIA + +VR L+
Sbjct: 45 GLNGLHLASKEGHVKMVVELLHK--EIILETTTKK---GNTALHIAALAGQDEVVRELVN 99
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
A+V+A++ G PL AA N E+V+ L+E+GA+ G T
Sbjct: 100 YGANVNAQSQK-------------GFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFT 146
Query: 199 VLHILILQPNKTFACQMYN-------------------------LLLSYDRHGDHLQPLD 233
L + + Q ++ + N +LL D + D L
Sbjct: 147 PLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTG 206
Query: 234 LVPNH--------------------------QGLTPFKLAGVEGNTVMFQHLMQK 262
P H G+TP +A GN +M + L+ +
Sbjct: 207 FTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDR 261
Score = 41.6 bits (96), Expect = 0.003
Identities = 56/236 (23%), Positives = 93/236 (39%), Gaps = 37/236 (15%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
SP+ +AA+ + + + LL+Y D ++ T LH+AA + A VL++ +
Sbjct: 307 SPIHMAAQGDHLDCVRLLLQY-DAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAK-- 363
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARA--------TGTAFRRSPC- 157
S G T LHIA ++ ++ LL AS+ A + P
Sbjct: 364 ---PNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIV 420
Query: 158 -NLIYFG----------EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQ 206
NL+ G E PL AA E+ + L+++ A + A+ T LH
Sbjct: 421 KNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAA-- 478
Query: 207 PNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
+ M LLL + + + + G TP +A EG+ L++K
Sbjct: 479 --RIGHTNMVKLLLENNANPN-------LATTAGHTPLHIAAREGHVETVLALLEK 525
>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
Length = 1880
Score = 73.9 bits (180), Expect = 5e-13
Identities = 68/233 (29%), Positives = 106/233 (45%), Gaps = 38/233 (16%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME--AAPE 104
+PL +AA++ V+ + LL+ E + G T LH+AA Y + A +L+E A P
Sbjct: 505 TPLHIAAREGHVETVLALLEKEASQACMT-KKGFTPLHVAAKYGKVRVAELLLERDAHPN 563
Query: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164
+ G T LH+AV + N+++V+ LL R SP + + G
Sbjct: 564 AAGK-------NGLTPLHVAVHHNNLDIVKLLLPRGG-------------SPHSPAWNGY 603
Query: 165 HPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDR 224
PL AA N E+ R L+++G A+ G T LH+ + + +M LLLS
Sbjct: 604 TPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGH----AEMVALLLSKQA 659
Query: 225 HGDHLQPLDLVPNHQGLTPFKLAGVEGNT----VMFQHLMQKRKHTQWTYGPL 273
+G+ + N GLTP L EG+ V+ +H + T+ Y PL
Sbjct: 660 NGN-------LGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPL 705
Score = 60.5 bits (145), Expect = 5e-09
Identities = 56/190 (29%), Positives = 80/190 (42%), Gaps = 23/190 (12%)
Query: 49 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 108
L +AA+++D + LL+ D G T LHIAA Y+NL A +L+ + F
Sbjct: 177 LHIAARNDDTRTAAVLLQ-NDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 109 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 168
P G T LHIA N+ +VR LL R A + + PL
Sbjct: 236 PQ-----NGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDEL-------------TPLH 277
Query: 169 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDH 228
AA I +L++HGA I+A+ G + +H+ + LLL YD D
Sbjct: 278 CAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDH----LDCVRLLLQYDAEIDD 333
Query: 229 LQPLDLVPNH 238
+ L P H
Sbjct: 334 ITLDHLTPLH 343
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/155 (30%), Positives = 70/155 (45%), Gaps = 23/155 (14%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A + + L+ Y +G + ALHIAA D+ A VL++ P
Sbjct: 146 TPLAVALQQGHENVVAHLINYGT-----KGKVRLPALHIAARNDDTRTAAVLLQNDPNPD 200
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
T G T LHIA +N+N+ + LL R ASV+ +P N G P
Sbjct: 201 VLSKT-----GFTPLHIAAHYENLNVAQLLLNRGASVNF---------TPQN----GITP 242
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
L A+ + +VRLL++ GA I + T LH
Sbjct: 243 LHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLH 277
Score = 48.1 bits (113), Expect = 3e-05
Identities = 42/156 (26%), Positives = 71/156 (45%), Gaps = 19/156 (12%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A K N V+ + LLK + G T LH+A+ +L L++
Sbjct: 373 TPLHIACKKNHVRVMELLLK-TGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS-- 429
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P S + + +T LH+A + + + LL +A V+A+A + P
Sbjct: 430 --PNVSNV-KVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD-------------QTP 473
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
L AA + +V+LL+E+ A+ + G+T LHI
Sbjct: 474 LHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHI 509
Score = 48.1 bits (113), Expect = 3e-05
Identities = 45/178 (25%), Positives = 77/178 (43%), Gaps = 32/178 (17%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A N++ + KLL H G T LHIAA + +E A L++
Sbjct: 571 TPLHVAVHHNNLDIV-KLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA- 628
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIY----- 161
+E +G T LH+A + +V LL+++A+ + G +P +L+
Sbjct: 629 ----NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNL---GNKSGLTPLHLVAQEGHV 681
Query: 162 ------------------FGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
G PL A+ + ++V+ L++H AD+ A+ LG + LH
Sbjct: 682 PVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLH 739
Score = 46.2 bits (108), Expect = 1e-04
Identities = 51/184 (27%), Positives = 73/184 (39%), Gaps = 42/184 (22%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE-- 104
+PL +AAK N V+ LL+Y + G T LH+AA + E +L+
Sbjct: 604 TPLHIAAKQNQVEVARSLLQYGG-SANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGN 662
Query: 105 -----------LVFE----PMTSELYE-----------GQTALHIAVVNQNMNLVRALLA 138
LV + P+ L + G T LH+A N+ LV+ LL
Sbjct: 663 LGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQ 722
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
+A V+A+ G PL AA +IV LL+++GA S G T
Sbjct: 723 HQADVNAKTK-------------LGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Query: 199 VLHI 202
L I
Sbjct: 770 PLAI 773
Score = 45.1 bits (105), Expect = 2e-04
Identities = 53/235 (22%), Positives = 88/235 (37%), Gaps = 69/235 (29%)
Query: 79 GETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLA 138
G LH+A+ +++ + L+ E++ E T + G TALHIA + +VR L+
Sbjct: 45 GLNGLHLASKEGHVKMVVELLHK--EIILETTTKK---GNTALHIAALAGQDEVVRELVN 99
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
A+V+A++ G PL AA N E+V+ L+E+GA+ G T
Sbjct: 100 YGANVNAQSQK-------------GFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFT 146
Query: 199 VLHILILQPNKTFACQMYN-------------------------LLLSYDRHGDHLQPLD 233
L + + Q ++ + N +LL D + D L
Sbjct: 147 PLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTG 206
Query: 234 LVPNH--------------------------QGLTPFKLAGVEGNTVMFQHLMQK 262
P H G+TP +A GN +M + L+ +
Sbjct: 207 FTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDR 261
Score = 41.6 bits (96), Expect = 0.003
Identities = 56/236 (23%), Positives = 93/236 (39%), Gaps = 37/236 (15%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
SP+ +AA+ + + + LL+Y D ++ T LH+AA + A VL++ +
Sbjct: 307 SPIHMAAQGDHLDCVRLLLQY-DAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAK-- 363
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARA--------TGTAFRRSPC- 157
S G T LHIA ++ ++ LL AS+ A + P
Sbjct: 364 ---PNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIV 420
Query: 158 -NLIYFG----------EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQ 206
NL+ G E PL AA E+ + L+++ A + A+ T LH
Sbjct: 421 KNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAA-- 478
Query: 207 PNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
+ M LLL + + + + G TP +A EG+ L++K
Sbjct: 479 --RIGHTNMVKLLLENNANPN-------LATTAGHTPLHIAAREGHVETVLALLEK 525
>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
Length = 1719
Score = 73.9 bits (180), Expect = 5e-13
Identities = 68/233 (29%), Positives = 106/233 (45%), Gaps = 38/233 (16%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME--AAPE 104
+PL +AA++ V+ + LL+ E + G T LH+AA Y + A +L+E A P
Sbjct: 505 TPLHIAAREGHVETVLALLEKEASQACMT-KKGFTPLHVAAKYGKVRVAELLLERDAHPN 563
Query: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164
+ G T LH+AV + N+++V+ LL R SP + + G
Sbjct: 564 AAGK-------NGLTPLHVAVHHNNLDIVKLLLPRGG-------------SPHSPAWNGY 603
Query: 165 HPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDR 224
PL AA N E+ R L+++G A+ G T LH+ + + +M LLLS
Sbjct: 604 TPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGH----AEMVALLLSKQA 659
Query: 225 HGDHLQPLDLVPNHQGLTPFKLAGVEGNT----VMFQHLMQKRKHTQWTYGPL 273
+G+ + N GLTP L EG+ V+ +H + T+ Y PL
Sbjct: 660 NGN-------LGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPL 705
Score = 60.5 bits (145), Expect = 5e-09
Identities = 56/190 (29%), Positives = 80/190 (42%), Gaps = 23/190 (12%)
Query: 49 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 108
L +AA+++D + LL+ D G T LHIAA Y+NL A +L+ + F
Sbjct: 177 LHIAARNDDTRTAAVLLQ-NDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 109 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 168
P G T LHIA N+ +VR LL R A + + PL
Sbjct: 236 PQ-----NGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDEL-------------TPLH 277
Query: 169 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDH 228
AA I +L++HGA I+A+ G + +H+ + LLL YD D
Sbjct: 278 CAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDH----LDCVRLLLQYDAEIDD 333
Query: 229 LQPLDLVPNH 238
+ L P H
Sbjct: 334 ITLDHLTPLH 343
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/155 (30%), Positives = 70/155 (45%), Gaps = 23/155 (14%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A + + L+ Y +G + ALHIAA D+ A VL++ P
Sbjct: 146 TPLAVALQQGHENVVAHLINYGT-----KGKVRLPALHIAARNDDTRTAAVLLQNDPNPD 200
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
T G T LHIA +N+N+ + LL R ASV+ +P N G P
Sbjct: 201 VLSKT-----GFTPLHIAAHYENLNVAQLLLNRGASVNF---------TPQN----GITP 242
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
L A+ + +VRLL++ GA I + T LH
Sbjct: 243 LHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLH 277
Score = 48.1 bits (113), Expect = 3e-05
Identities = 42/156 (26%), Positives = 71/156 (45%), Gaps = 19/156 (12%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A K N V+ + LLK + G T LH+A+ +L L++
Sbjct: 373 TPLHIACKKNHVRVMELLLK-TGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS-- 429
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P S + + +T LH+A + + + LL +A V+A+A + P
Sbjct: 430 --PNVSNV-KVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD-------------QTP 473
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
L AA + +V+LL+E+ A+ + G+T LHI
Sbjct: 474 LHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHI 509
Score = 48.1 bits (113), Expect = 3e-05
Identities = 45/178 (25%), Positives = 77/178 (43%), Gaps = 32/178 (17%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A N++ + KLL H G T LHIAA + +E A L++
Sbjct: 571 TPLHVAVHHNNLDIV-KLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA- 628
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIY----- 161
+E +G T LH+A + +V LL+++A+ + G +P +L+
Sbjct: 629 ----NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNL---GNKSGLTPLHLVAQEGHV 681
Query: 162 ------------------FGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
G PL A+ + ++V+ L++H AD+ A+ LG + LH
Sbjct: 682 PVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLH 739
Score = 46.2 bits (108), Expect = 1e-04
Identities = 51/184 (27%), Positives = 73/184 (39%), Gaps = 42/184 (22%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE-- 104
+PL +AAK N V+ LL+Y + G T LH+AA + E +L+
Sbjct: 604 TPLHIAAKQNQVEVARSLLQYGG-SANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGN 662
Query: 105 -----------LVFE----PMTSELYE-----------GQTALHIAVVNQNMNLVRALLA 138
LV + P+ L + G T LH+A N+ LV+ LL
Sbjct: 663 LGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQ 722
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
+A V+A+ G PL AA +IV LL+++GA S G T
Sbjct: 723 HQADVNAKTK-------------LGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Query: 199 VLHI 202
L I
Sbjct: 770 PLAI 773
Score = 45.1 bits (105), Expect = 2e-04
Identities = 53/235 (22%), Positives = 88/235 (37%), Gaps = 69/235 (29%)
Query: 79 GETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLA 138
G LH+A+ +++ + L+ E++ E T + G TALHIA + +VR L+
Sbjct: 45 GLNGLHLASKEGHVKMVVELLHK--EIILETTTKK---GNTALHIAALAGQDEVVRELVN 99
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
A+V+A++ G PL AA N E+V+ L+E+GA+ G T
Sbjct: 100 YGANVNAQSQK-------------GFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFT 146
Query: 199 VLHILILQPNKTFACQMYN-------------------------LLLSYDRHGDHLQPLD 233
L + + Q ++ + N +LL D + D L
Sbjct: 147 PLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTG 206
Query: 234 LVPNH--------------------------QGLTPFKLAGVEGNTVMFQHLMQK 262
P H G+TP +A GN +M + L+ +
Sbjct: 207 FTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDR 261
Score = 41.6 bits (96), Expect = 0.003
Identities = 56/236 (23%), Positives = 93/236 (39%), Gaps = 37/236 (15%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
SP+ +AA+ + + + LL+Y D ++ T LH+AA + A VL++ +
Sbjct: 307 SPIHMAAQGDHLDCVRLLLQY-DAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAK-- 363
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARA--------TGTAFRRSPC- 157
S G T LHIA ++ ++ LL AS+ A + P
Sbjct: 364 ---PNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIV 420
Query: 158 -NLIYFG----------EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQ 206
NL+ G E PL AA E+ + L+++ A + A+ T LH
Sbjct: 421 KNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAA-- 478
Query: 207 PNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
+ M LLL + + + + G TP +A EG+ L++K
Sbjct: 479 --RIGHTNMVKLLLENNANPN-------LATTAGHTPLHIAAREGHVETVLALLEK 525
>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
Length = 1856
Score = 73.9 bits (180), Expect = 5e-13
Identities = 68/233 (29%), Positives = 106/233 (45%), Gaps = 38/233 (16%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME--AAPE 104
+PL +AA++ V+ + LL+ E + G T LH+AA Y + A +L+E A P
Sbjct: 505 TPLHIAAREGHVETVLALLEKEASQACMT-KKGFTPLHVAAKYGKVRVAELLLERDAHPN 563
Query: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164
+ G T LH+AV + N+++V+ LL R SP + + G
Sbjct: 564 AAGK-------NGLTPLHVAVHHNNLDIVKLLLPRGG-------------SPHSPAWNGY 603
Query: 165 HPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDR 224
PL AA N E+ R L+++G A+ G T LH+ + + +M LLLS
Sbjct: 604 TPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGH----AEMVALLLSKQA 659
Query: 225 HGDHLQPLDLVPNHQGLTPFKLAGVEGNT----VMFQHLMQKRKHTQWTYGPL 273
+G+ + N GLTP L EG+ V+ +H + T+ Y PL
Sbjct: 660 NGN-------LGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPL 705
Score = 60.5 bits (145), Expect = 5e-09
Identities = 56/190 (29%), Positives = 80/190 (42%), Gaps = 23/190 (12%)
Query: 49 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 108
L +AA+++D + LL+ D G T LHIAA Y+NL A +L+ + F
Sbjct: 177 LHIAARNDDTRTAAVLLQ-NDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 109 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 168
P G T LHIA N+ +VR LL R A + + PL
Sbjct: 236 PQ-----NGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDEL-------------TPLH 277
Query: 169 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDH 228
AA I +L++HGA I+A+ G + +H+ + LLL YD D
Sbjct: 278 CAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDH----LDCVRLLLQYDAEIDD 333
Query: 229 LQPLDLVPNH 238
+ L P H
Sbjct: 334 ITLDHLTPLH 343
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/155 (30%), Positives = 70/155 (45%), Gaps = 23/155 (14%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A + + L+ Y +G + ALHIAA D+ A VL++ P
Sbjct: 146 TPLAVALQQGHENVVAHLINYGT-----KGKVRLPALHIAARNDDTRTAAVLLQNDPNPD 200
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
T G T LHIA +N+N+ + LL R ASV+ +P N G P
Sbjct: 201 VLSKT-----GFTPLHIAAHYENLNVAQLLLNRGASVNF---------TPQN----GITP 242
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
L A+ + +VRLL++ GA I + T LH
Sbjct: 243 LHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLH 277
Score = 48.1 bits (113), Expect = 3e-05
Identities = 42/156 (26%), Positives = 71/156 (45%), Gaps = 19/156 (12%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A K N V+ + LLK + G T LH+A+ +L L++
Sbjct: 373 TPLHIACKKNHVRVMELLLK-TGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS-- 429
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P S + + +T LH+A + + + LL +A V+A+A + P
Sbjct: 430 --PNVSNV-KVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD-------------QTP 473
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
L AA + +V+LL+E+ A+ + G+T LHI
Sbjct: 474 LHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHI 509
Score = 48.1 bits (113), Expect = 3e-05
Identities = 45/178 (25%), Positives = 77/178 (43%), Gaps = 32/178 (17%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A N++ + KLL H G T LHIAA + +E A L++
Sbjct: 571 TPLHVAVHHNNLDIV-KLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA- 628
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIY----- 161
+E +G T LH+A + +V LL+++A+ + G +P +L+
Sbjct: 629 ----NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNL---GNKSGLTPLHLVAQEGHV 681
Query: 162 ------------------FGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
G PL A+ + ++V+ L++H AD+ A+ LG + LH
Sbjct: 682 PVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLH 739
Score = 46.2 bits (108), Expect = 1e-04
Identities = 51/184 (27%), Positives = 73/184 (39%), Gaps = 42/184 (22%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE-- 104
+PL +AAK N V+ LL+Y + G T LH+AA + E +L+
Sbjct: 604 TPLHIAAKQNQVEVARSLLQYGG-SANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGN 662
Query: 105 -----------LVFE----PMTSELYE-----------GQTALHIAVVNQNMNLVRALLA 138
LV + P+ L + G T LH+A N+ LV+ LL
Sbjct: 663 LGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQ 722
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
+A V+A+ G PL AA +IV LL+++GA S G T
Sbjct: 723 HQADVNAKTK-------------LGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Query: 199 VLHI 202
L I
Sbjct: 770 PLAI 773
Score = 45.1 bits (105), Expect = 2e-04
Identities = 53/235 (22%), Positives = 88/235 (37%), Gaps = 69/235 (29%)
Query: 79 GETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLA 138
G LH+A+ +++ + L+ E++ E T + G TALHIA + +VR L+
Sbjct: 45 GLNGLHLASKEGHVKMVVELLHK--EIILETTTKK---GNTALHIAALAGQDEVVRELVN 99
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
A+V+A++ G PL AA N E+V+ L+E+GA+ G T
Sbjct: 100 YGANVNAQSQK-------------GFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFT 146
Query: 199 VLHILILQPNKTFACQMYN-------------------------LLLSYDRHGDHLQPLD 233
L + + Q ++ + N +LL D + D L
Sbjct: 147 PLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTG 206
Query: 234 LVPNH--------------------------QGLTPFKLAGVEGNTVMFQHLMQK 262
P H G+TP +A GN +M + L+ +
Sbjct: 207 FTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDR 261
Score = 41.6 bits (96), Expect = 0.003
Identities = 56/236 (23%), Positives = 93/236 (39%), Gaps = 37/236 (15%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
SP+ +AA+ + + + LL+Y D ++ T LH+AA + A VL++ +
Sbjct: 307 SPIHMAAQGDHLDCVRLLLQY-DAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAK-- 363
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARA--------TGTAFRRSPC- 157
S G T LHIA ++ ++ LL AS+ A + P
Sbjct: 364 ---PNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIV 420
Query: 158 -NLIYFG----------EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQ 206
NL+ G E PL AA E+ + L+++ A + A+ T LH
Sbjct: 421 KNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAA-- 478
Query: 207 PNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
+ M LLL + + + + G TP +A EG+ L++K
Sbjct: 479 --RIGHTNMVKLLLENNANPN-------LATTAGHTPLHIAAREGHVETVLALLEK 525
>gi|116534990 ankyrin-like protein 1 [Homo sapiens]
Length = 1119
Score = 64.7 bits (156), Expect = 3e-10
Identities = 135/617 (21%), Positives = 240/617 (38%), Gaps = 88/617 (14%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL A + ++N LL + + +H + ++ LH AA Y + L++ +
Sbjct: 415 TPLHYACRQGGPGSVNNLLGF-NVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTR 473
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATG-TAFRRSPCN------- 158
+ G T LH+A N + +V+ LL + A + G TA +
Sbjct: 474 L--LNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALFLSDHNGWTALHHASMGGYTQTMK 531
Query: 159 ------------LIYFGEHPLSFAACVNSEEIVRLLIEHGADI---RAQDSLGNTVLH-- 201
L G L FAA + V LL+ H ADI + Q S + LH
Sbjct: 532 VILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK 591
Query: 202 -----ILILQPNKTFACQMYNLLLSYDRHGDH---LQPLDLVPN-HQGLTPF-KLAGVEG 251
+ I++ + C + S++ G+ + ++ +P + L F L E
Sbjct: 592 RKEVVLTIIRSKRWDECLK---IFSHNSPGNKCPITEMIEYLPECMKVLLDFCMLHSTED 648
Query: 252 NTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREARQILDQT 311
+ ++ K+ Q PL T T+ D + + L ++ + E +L+
Sbjct: 649 KSCRDYYIEYNFKYLQC---PLEFTKKTPTQ-DVIYEPLTALNAMVQNNRIE---LLNHP 701
Query: 312 PVKELVSLKWKRYG-RPYFCMLGAIYLLYIICFTMCCIYRPLKP-RTNNRTSPRDNTLLQ 369
KE + +KW YG R + LG+ Y L +I T+ + +KP N T + T
Sbjct: 702 VCKEYLLMKWLAYGFRAHMMNLGS-YCLGLIPMTILVV--NIKPGMAFNSTGIINETSDH 758
Query: 370 QKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFG-QTILGGPFHVL 428
++L T + ++ + +I E IF+ F +L +
Sbjct: 759 SEILD----TTNSYLIKTCMILVFLSSIFGYCKEAGQIFQQKRNYFMDISNVLEWIIYTT 814
Query: 429 IITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFG 488
I + + V + L G + A+ W N + + + F+ G F +M++ +I
Sbjct: 815 GIIFVLPLFVEIPAHLQWQCGAI-----AVYFYWMNFLLYLQRFENCGIFIVMLE-VILK 868
Query: 489 DLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGPANYN 548
L+R + ++L F +FYI+ +DP F +++ TF + L G NY
Sbjct: 869 TLLRSTVVFIFLLLAFGLSFYILLNLQDP-----FSSPLLSIIQTFSMML----GDINYR 919
Query: 549 VDL-----------PFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQ 596
P + +F I ++++NLLI + +GD H + Q
Sbjct: 920 ESFLEPYLRNELAHPVLSFAQLVSFTIFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQ 979
Query: 597 IVATTVMLERKLPRCLW 613
+ T LE+KLP LW
Sbjct: 980 VELHT-SLEKKLP--LW 993
Score = 34.7 bits (78), Expect = 0.32
Identities = 44/195 (22%), Positives = 74/195 (37%), Gaps = 53/195 (27%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME--AAP- 103
+PL +A + + + + LL++ V+ G G TA+ IA +N EA +L++ A P
Sbjct: 133 APLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQILLKKGAKPC 192
Query: 104 ----------------------ELVFEPMTSELYEGQ-----------TALHIAVVNQNM 130
E++ Y Q T LH+AV N ++
Sbjct: 193 KSNKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDL 252
Query: 131 NLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGAD-- 188
+++ L A + G C I+ FAA + EIV+L+I +
Sbjct: 253 EMIKMCLDNGAQIDPVEKGR------CTAIH-------FAATQGATEIVKLMISSYSGSV 299
Query: 189 --IRAQDSLGNTVLH 201
+ D T+LH
Sbjct: 300 DIVNTTDGCHETMLH 314
Score = 32.3 bits (72), Expect = 1.6
Identities = 40/159 (25%), Positives = 62/159 (38%), Gaps = 23/159 (14%)
Query: 58 VQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEG 117
+Q NK K + C M LH AA +E + + V M G
Sbjct: 47 LQNFNKQKKLKRCD-----DMDTFFLHYAAAEGQIELMEKITRDSSLEVLHEMDDY---G 98
Query: 118 QTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEE 177
T LH AV + V+ LL+R A+ + R PL A + E
Sbjct: 99 NTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMM-------------APLHIAVQGMNNE 145
Query: 178 IVRLLIEHGA-DIRAQDSLGNTVLHILILQPNKTFACQM 215
++++L+EH D+ + GNT + I+ N + A Q+
Sbjct: 146 VMKVLLEHRTIDVNLEGENGNTAV-IIACTTNNSEALQI 183
Score = 31.6 bits (70), Expect = 2.7
Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 5/67 (7%)
Query: 80 ETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLAR 139
ET LH A+L+D+ E A L+ ++ + SE G++ L +A + + N+V LL++
Sbjct: 310 ETMLHRASLFDHHELADYLISVGADI--NKIDSE---GRSPLILATASASWNIVNLLLSK 364
Query: 140 RASVSAR 146
A V +
Sbjct: 365 GAQVDIK 371
>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
Length = 1863
Score = 64.7 bits (156), Expect = 3e-10
Identities = 73/273 (26%), Positives = 117/273 (42%), Gaps = 43/273 (15%)
Query: 46 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAM--GETALHIAALYDNLEAAMVLMEAAP 103
++PL +A++ + + LL++ H A G T LHI+A ++ A VL+EA
Sbjct: 477 QTPLHIASRLGKTEIVQLLLQH---MAHPDAATTNGYTPLHISAREGQVDVASVLLEAGA 533
Query: 104 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFG 163
+ +G T LH+A ++++ + LL RRA+ + G
Sbjct: 534 A-----HSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKN-------------G 575
Query: 164 EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 223
PL AA +++++ LL+E GA A G T LHI K Q+ + LL+Y
Sbjct: 576 LTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAA----KKNQMQIASTLLNYG 631
Query: 224 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEI 283
+ + QG+TP LA EG+T M L+ K + ST LT +
Sbjct: 632 AETN-------IVTKQGVTPLHLASQEGHTDMVTLLLDKGANIH------MSTKSGLTSL 678
Query: 284 DSSGDEQSLLELIITTK---KREARQILDQTPV 313
+ E + I TK ++A L TP+
Sbjct: 679 HLAAQEDKVNVADILTKHGADQDAHTKLGYTPL 711
Score = 62.0 bits (149), Expect = 2e-09
Identities = 57/219 (26%), Positives = 97/219 (44%), Gaps = 34/219 (15%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME--AAPE 104
+PL +A K N ++ + L+KY + G T +H+AA +L ++L++ A+P+
Sbjct: 379 TPLHIACKKNRIKVMELLVKY-GASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPD 437
Query: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164
+ G+TALH+A + +VR LL A V ARA +
Sbjct: 438 VTN-------IRGETALHMAARAGQVEVVRCLLRNGALVDARAREE-------------Q 477
Query: 165 HPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDR 224
PL A+ + EIV+LL++H A A + G T LHI + A + ++
Sbjct: 478 TPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHS- 536
Query: 225 HGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 263
+ +G TP +A G+ + + L+Q+R
Sbjct: 537 ----------LATKKGFTPLHVAAKYGSLDVAKLLLQRR 565
Score = 56.2 bits (134), Expect = 1e-07
Identities = 45/157 (28%), Positives = 70/157 (44%), Gaps = 24/157 (15%)
Query: 46 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 105
+S LL D++ +K++ V++ G T LHIAA Y N+ A +L+ +
Sbjct: 185 KSAALLLQNDHNADVQSKMM------VNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAV 238
Query: 106 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH 165
F G T LH+A N N+V+ LL R + A+ G
Sbjct: 239 DFTARN-----GITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD-------------GLT 280
Query: 166 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
PL AA +++V LL+E GA + A+ G + LH+
Sbjct: 281 PLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHM 317
Score = 54.3 bits (129), Expect = 4e-07
Identities = 58/218 (26%), Positives = 84/218 (38%), Gaps = 34/218 (15%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME--AAPE 104
+PL +AAK + KLL G G T LH+AA YDN + A++L+E A+P
Sbjct: 544 TPLHVAAKYGSLDVA-KLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPH 602
Query: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164
+ G T LHIA M + LL A + + G
Sbjct: 603 ATAK-------NGYTPLHIAAKKNQMQIASTLLNYGAETNI-------------VTKQGV 642
Query: 165 HPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDR 224
PL A+ ++V LL++ GA+I G T LH+ + A + D
Sbjct: 643 TPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDA 702
Query: 225 HGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
H G TP +A GN M L+++
Sbjct: 703 H-----------TKLGYTPLIVACHYGNVKMVNFLLKQ 729
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/220 (27%), Positives = 98/220 (44%), Gaps = 32/220 (14%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLM--EAAPE 104
+PL +A + QA+ LL+ + +G + ALHIAA D+ ++A +L+ + +
Sbjct: 144 TPLAVALQQGHNQAVAILLENDT-----KGKVRLPALHIAARKDDTKSAALLLQNDHNAD 198
Query: 105 LVFEPMTSELYE-GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFG 163
+ + M + E G T LHIA N+N+ LL R A+V A G
Sbjct: 199 VQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN-------------G 245
Query: 164 EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 223
PL A+ + +V+LL++ G I A+ G T LH + Q+ LLL
Sbjct: 246 ITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHD----QVVELLL--- 298
Query: 224 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 263
+ PL L GL+P +A + +HL+Q +
Sbjct: 299 ---ERGAPL-LARTKNGLSPLHMAAQGDHVECVKHLLQHK 334
Score = 50.8 bits (120), Expect = 4e-06
Identities = 45/168 (26%), Positives = 76/168 (45%), Gaps = 21/168 (12%)
Query: 35 EQNLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEA 94
E N++ ++ + +PL LA+++ + LL + +H G T+LH+AA D +
Sbjct: 633 ETNIVTKQGV--TPLHLASQEGHTDMVTLLLD-KGANIHMSTKSGLTSLHLAAQEDKVNV 689
Query: 95 AMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRR 154
A +L + + + G T L +A N+ +V LL + A+V+A+
Sbjct: 690 ADILTKHGAD-----QDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKN----- 739
Query: 155 SPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
G PL AA I+ +L++HGA A + GNT L I
Sbjct: 740 --------GYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAI 779
Score = 49.3 bits (116), Expect = 1e-05
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 19/156 (12%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL AA+ Q + LL+ + R G + LH+AA D++E L++
Sbjct: 280 TPLHCAARSGHDQVVELLLE-RGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKA--- 335
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P+ + TALH+A + + + LL +RA+ +ARA G P
Sbjct: 336 --PVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALN-------------GFTP 380
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
L A N +++ LL+++GA I+A G T +H+
Sbjct: 381 LHIACKKNRIKVMELLVKYGASIQAITESGLTPIHV 416
Score = 40.4 bits (93), Expect = 0.006
Identities = 46/186 (24%), Positives = 79/186 (42%), Gaps = 23/186 (12%)
Query: 41 QKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME 100
QK + L AA+ ++ + + LK ++ G ALH+AA ++ L+
Sbjct: 6 QKSDSNASFLRAARAGNLDKVVEYLK-GGIDINTCNQNGLNALHLAAKEGHVGLVQELLG 64
Query: 101 AAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLI 160
+ S +G TALHIA + +V+ L+ A+++A++
Sbjct: 65 RGSSV-----DSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQN----------- 108
Query: 161 YFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 220
G PL AA N ++V+ L+E+GA+ G T L + + Q + Q +LL
Sbjct: 109 --GFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHN----QAVAILL 162
Query: 221 SYDRHG 226
D G
Sbjct: 163 ENDTKG 168
>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
Length = 1872
Score = 64.7 bits (156), Expect = 3e-10
Identities = 73/273 (26%), Positives = 117/273 (42%), Gaps = 43/273 (15%)
Query: 46 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAM--GETALHIAALYDNLEAAMVLMEAAP 103
++PL +A++ + + LL++ H A G T LHI+A ++ A VL+EA
Sbjct: 498 QTPLHIASRLGKTEIVQLLLQH---MAHPDAATTNGYTPLHISAREGQVDVASVLLEAGA 554
Query: 104 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFG 163
+ +G T LH+A ++++ + LL RRA+ + G
Sbjct: 555 A-----HSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKN-------------G 596
Query: 164 EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 223
PL AA +++++ LL+E GA A G T LHI K Q+ + LL+Y
Sbjct: 597 LTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAA----KKNQMQIASTLLNYG 652
Query: 224 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEI 283
+ + QG+TP LA EG+T M L+ K + ST LT +
Sbjct: 653 AETN-------IVTKQGVTPLHLASQEGHTDMVTLLLDKGANIH------MSTKSGLTSL 699
Query: 284 DSSGDEQSLLELIITTK---KREARQILDQTPV 313
+ E + I TK ++A L TP+
Sbjct: 700 HLAAQEDKVNVADILTKHGADQDAHTKLGYTPL 732
Score = 62.0 bits (149), Expect = 2e-09
Identities = 57/219 (26%), Positives = 97/219 (44%), Gaps = 34/219 (15%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME--AAPE 104
+PL +A K N ++ + L+KY + G T +H+AA +L ++L++ A+P+
Sbjct: 400 TPLHIACKKNRIKVMELLVKY-GASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPD 458
Query: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164
+ G+TALH+A + +VR LL A V ARA +
Sbjct: 459 VTN-------IRGETALHMAARAGQVEVVRCLLRNGALVDARAREE-------------Q 498
Query: 165 HPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDR 224
PL A+ + EIV+LL++H A A + G T LHI + A + ++
Sbjct: 499 TPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHS- 557
Query: 225 HGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 263
+ +G TP +A G+ + + L+Q+R
Sbjct: 558 ----------LATKKGFTPLHVAAKYGSLDVAKLLLQRR 586
Score = 56.2 bits (134), Expect = 1e-07
Identities = 45/157 (28%), Positives = 70/157 (44%), Gaps = 24/157 (15%)
Query: 46 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 105
+S LL D++ +K++ V++ G T LHIAA Y N+ A +L+ +
Sbjct: 206 KSAALLLQNDHNADVQSKMM------VNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAV 259
Query: 106 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH 165
F G T LH+A N N+V+ LL R + A+ G
Sbjct: 260 DFTARN-----GITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD-------------GLT 301
Query: 166 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
PL AA +++V LL+E GA + A+ G + LH+
Sbjct: 302 PLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHM 338
Score = 54.3 bits (129), Expect = 4e-07
Identities = 58/218 (26%), Positives = 84/218 (38%), Gaps = 34/218 (15%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME--AAPE 104
+PL +AAK + KLL G G T LH+AA YDN + A++L+E A+P
Sbjct: 565 TPLHVAAKYGSLDVA-KLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPH 623
Query: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164
+ G T LHIA M + LL A + + G
Sbjct: 624 ATAK-------NGYTPLHIAAKKNQMQIASTLLNYGAETNI-------------VTKQGV 663
Query: 165 HPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDR 224
PL A+ ++V LL++ GA+I G T LH+ + A + D
Sbjct: 664 TPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDA 723
Query: 225 HGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
H G TP +A GN M L+++
Sbjct: 724 H-----------TKLGYTPLIVACHYGNVKMVNFLLKQ 750
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/220 (27%), Positives = 98/220 (44%), Gaps = 32/220 (14%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLM--EAAPE 104
+PL +A + QA+ LL+ + +G + ALHIAA D+ ++A +L+ + +
Sbjct: 165 TPLAVALQQGHNQAVAILLENDT-----KGKVRLPALHIAARKDDTKSAALLLQNDHNAD 219
Query: 105 LVFEPMTSELYE-GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFG 163
+ + M + E G T LHIA N+N+ LL R A+V A G
Sbjct: 220 VQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN-------------G 266
Query: 164 EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 223
PL A+ + +V+LL++ G I A+ G T LH + Q+ LLL
Sbjct: 267 ITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHD----QVVELLL--- 319
Query: 224 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 263
+ PL L GL+P +A + +HL+Q +
Sbjct: 320 ---ERGAPL-LARTKNGLSPLHMAAQGDHVECVKHLLQHK 355
Score = 50.8 bits (120), Expect = 4e-06
Identities = 45/168 (26%), Positives = 76/168 (45%), Gaps = 21/168 (12%)
Query: 35 EQNLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEA 94
E N++ ++ + +PL LA+++ + LL + +H G T+LH+AA D +
Sbjct: 654 ETNIVTKQGV--TPLHLASQEGHTDMVTLLLD-KGANIHMSTKSGLTSLHLAAQEDKVNV 710
Query: 95 AMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRR 154
A +L + + + G T L +A N+ +V LL + A+V+A+
Sbjct: 711 ADILTKHGAD-----QDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKN----- 760
Query: 155 SPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
G PL AA I+ +L++HGA A + GNT L I
Sbjct: 761 --------GYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAI 800
Score = 49.3 bits (116), Expect = 1e-05
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 19/156 (12%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL AA+ Q + LL+ + R G + LH+AA D++E L++
Sbjct: 301 TPLHCAARSGHDQVVELLLE-RGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKA--- 356
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P+ + TALH+A + + + LL +RA+ +ARA G P
Sbjct: 357 --PVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALN-------------GFTP 401
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
L A N +++ LL+++GA I+A G T +H+
Sbjct: 402 LHIACKKNRIKVMELLVKYGASIQAITESGLTPIHV 437
Score = 40.0 bits (92), Expect = 0.008
Identities = 39/148 (26%), Positives = 64/148 (43%), Gaps = 22/148 (14%)
Query: 79 GETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLA 138
G ALH+AA ++ L+ + S +G TALHIA + +V+ L+
Sbjct: 64 GLNALHLAAKEGHVGLVQELLGRGSSV-----DSATKKGNTALHIASLAGQAEVVKVLVK 118
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
A+++A++ G PL AA N ++V+ L+E+GA+ G T
Sbjct: 119 EGANINAQSQN-------------GFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFT 165
Query: 199 VLHILILQPNKTFACQMYNLLLSYDRHG 226
L + + Q + Q +LL D G
Sbjct: 166 PLAVALQQGHN----QAVAILLENDTKG 189
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 64.7 bits (156), Expect = 3e-10
Identities = 73/273 (26%), Positives = 117/273 (42%), Gaps = 43/273 (15%)
Query: 46 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAM--GETALHIAALYDNLEAAMVLMEAAP 103
++PL +A++ + + LL++ H A G T LHI+A ++ A VL+EA
Sbjct: 498 QTPLHIASRLGKTEIVQLLLQH---MAHPDAATTNGYTPLHISAREGQVDVASVLLEAGA 554
Query: 104 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFG 163
+ +G T LH+A ++++ + LL RRA+ + G
Sbjct: 555 A-----HSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKN-------------G 596
Query: 164 EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 223
PL AA +++++ LL+E GA A G T LHI K Q+ + LL+Y
Sbjct: 597 LTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAA----KKNQMQIASTLLNYG 652
Query: 224 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEI 283
+ + QG+TP LA EG+T M L+ K + ST LT +
Sbjct: 653 AETN-------IVTKQGVTPLHLASQEGHTDMVTLLLDKGANIH------MSTKSGLTSL 699
Query: 284 DSSGDEQSLLELIITTK---KREARQILDQTPV 313
+ E + I TK ++A L TP+
Sbjct: 700 HLAAQEDKVNVADILTKHGADQDAHTKLGYTPL 732
Score = 62.0 bits (149), Expect = 2e-09
Identities = 57/219 (26%), Positives = 97/219 (44%), Gaps = 34/219 (15%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME--AAPE 104
+PL +A K N ++ + L+KY + G T +H+AA +L ++L++ A+P+
Sbjct: 400 TPLHIACKKNRIKVMELLVKY-GASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPD 458
Query: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164
+ G+TALH+A + +VR LL A V ARA +
Sbjct: 459 VTN-------IRGETALHMAARAGQVEVVRCLLRNGALVDARAREE-------------Q 498
Query: 165 HPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDR 224
PL A+ + EIV+LL++H A A + G T LHI + A + ++
Sbjct: 499 TPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHS- 557
Query: 225 HGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 263
+ +G TP +A G+ + + L+Q+R
Sbjct: 558 ----------LATKKGFTPLHVAAKYGSLDVAKLLLQRR 586
Score = 56.2 bits (134), Expect = 1e-07
Identities = 45/157 (28%), Positives = 70/157 (44%), Gaps = 24/157 (15%)
Query: 46 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 105
+S LL D++ +K++ V++ G T LHIAA Y N+ A +L+ +
Sbjct: 206 KSAALLLQNDHNADVQSKMM------VNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAV 259
Query: 106 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH 165
F G T LH+A N N+V+ LL R + A+ G
Sbjct: 260 DFTARN-----GITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD-------------GLT 301
Query: 166 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
PL AA +++V LL+E GA + A+ G + LH+
Sbjct: 302 PLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHM 338
Score = 54.3 bits (129), Expect = 4e-07
Identities = 58/218 (26%), Positives = 84/218 (38%), Gaps = 34/218 (15%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME--AAPE 104
+PL +AAK + KLL G G T LH+AA YDN + A++L+E A+P
Sbjct: 565 TPLHVAAKYGSLDVA-KLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPH 623
Query: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164
+ G T LHIA M + LL A + + G
Sbjct: 624 ATAK-------NGYTPLHIAAKKNQMQIASTLLNYGAETNI-------------VTKQGV 663
Query: 165 HPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDR 224
PL A+ ++V LL++ GA+I G T LH+ + A + D
Sbjct: 664 TPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDA 723
Query: 225 HGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
H G TP +A GN M L+++
Sbjct: 724 H-----------TKLGYTPLIVACHYGNVKMVNFLLKQ 750
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/220 (27%), Positives = 98/220 (44%), Gaps = 32/220 (14%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLM--EAAPE 104
+PL +A + QA+ LL+ + +G + ALHIAA D+ ++A +L+ + +
Sbjct: 165 TPLAVALQQGHNQAVAILLENDT-----KGKVRLPALHIAARKDDTKSAALLLQNDHNAD 219
Query: 105 LVFEPMTSELYE-GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFG 163
+ + M + E G T LHIA N+N+ LL R A+V A G
Sbjct: 220 VQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN-------------G 266
Query: 164 EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 223
PL A+ + +V+LL++ G I A+ G T LH + Q+ LLL
Sbjct: 267 ITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHD----QVVELLL--- 319
Query: 224 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 263
+ PL L GL+P +A + +HL+Q +
Sbjct: 320 ---ERGAPL-LARTKNGLSPLHMAAQGDHVECVKHLLQHK 355
Score = 50.8 bits (120), Expect = 4e-06
Identities = 45/168 (26%), Positives = 76/168 (45%), Gaps = 21/168 (12%)
Query: 35 EQNLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEA 94
E N++ ++ + +PL LA+++ + LL + +H G T+LH+AA D +
Sbjct: 654 ETNIVTKQGV--TPLHLASQEGHTDMVTLLLD-KGANIHMSTKSGLTSLHLAAQEDKVNV 710
Query: 95 AMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRR 154
A +L + + + G T L +A N+ +V LL + A+V+A+
Sbjct: 711 ADILTKHGAD-----QDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKN----- 760
Query: 155 SPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
G PL AA I+ +L++HGA A + GNT L I
Sbjct: 761 --------GYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAI 800
Score = 49.3 bits (116), Expect = 1e-05
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 19/156 (12%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL AA+ Q + LL+ + R G + LH+AA D++E L++
Sbjct: 301 TPLHCAARSGHDQVVELLLE-RGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKA--- 356
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P+ + TALH+A + + + LL +RA+ +ARA G P
Sbjct: 357 --PVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALN-------------GFTP 401
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
L A N +++ LL+++GA I+A G T +H+
Sbjct: 402 LHIACKKNRIKVMELLVKYGASIQAITESGLTPIHV 437
Score = 40.0 bits (92), Expect = 0.008
Identities = 39/148 (26%), Positives = 64/148 (43%), Gaps = 22/148 (14%)
Query: 79 GETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLA 138
G ALH+AA ++ L+ + S +G TALHIA + +V+ L+
Sbjct: 64 GLNALHLAAKEGHVGLVQELLGRGSSV-----DSATKKGNTALHIASLAGQAEVVKVLVK 118
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
A+++A++ G PL AA N ++V+ L+E+GA+ G T
Sbjct: 119 EGANINAQSQN-------------GFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFT 165
Query: 199 VLHILILQPNKTFACQMYNLLLSYDRHG 226
L + + Q + Q +LL D G
Sbjct: 166 PLAVALQQGHN----QAVAILLENDTKG 189
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 63.9 bits (154), Expect = 5e-10
Identities = 77/284 (27%), Positives = 116/284 (40%), Gaps = 38/284 (13%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
S L LAAK++ + + KLL+ + C + G+TALH AA L+A +L E
Sbjct: 88 SALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHK---- 142
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P+ + +G L +AV N + + LL A V++R G
Sbjct: 143 -SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKS-------------GRTA 188
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLS-YDRH 225
L A + S V LI+ GAD+ DSLG LH L N + +LLLS +
Sbjct: 189 LMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSEN----AGIQSLLLSKISQD 244
Query: 226 GDHLQP-----LDLVPNHQGLTPFKLAGVEG---NTVMFQHLMQKRKHTQWTYGPLTSTL 277
D P L V + + +T L+G E F+ + + + T+
Sbjct: 245 ADLKTPTKPKQLSDVSSPRSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSDSTTGA 304
Query: 278 YDLTEIDSSGDEQSLLELI------ITTKKREARQILDQTPVKE 315
L +I S D+Q LL L+ +T +E + L KE
Sbjct: 305 DSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKE 348
Score = 54.7 bits (130), Expect = 3e-07
Identities = 45/172 (26%), Positives = 73/172 (42%), Gaps = 25/172 (14%)
Query: 49 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 108
LL A ++ D + + LL + + + G+TA H+AA ++E V++ ++ +
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQ 82
Query: 109 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVS------------ARATG------- 149
T G +ALH+A N + +R LL + A A G
Sbjct: 83 DTT-----GHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQI 137
Query: 150 TAFRRSPCNLIYF-GEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVL 200
+SP NL G PL A EI L++HGAD+ +++ G T L
Sbjct: 138 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTAL 189
Score = 37.0 bits (84), Expect = 0.065
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 12/92 (13%)
Query: 111 TSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFA 170
T+E + L AV N + V +LL ++ + + + G+ A
Sbjct: 13 TNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSE------------GKTAFHLA 60
Query: 171 ACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
A E +R++I HG D+ AQD+ G++ LH+
Sbjct: 61 AAKGHVECLRVMITHGVDVTAQDTTGHSALHL 92
Score = 36.6 bits (83), Expect = 0.084
Identities = 41/179 (22%), Positives = 69/179 (38%), Gaps = 24/179 (13%)
Query: 116 EGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 175
EG+TA H+A ++ +R ++ V+A+ T G L AA +
Sbjct: 52 EGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT-------------GHSALHLAAKNSH 98
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLV 235
E +R L++ + DS G T LH Q Q +L +H P++L
Sbjct: 99 HECIRKLLQSKCPAESVDSSGKTALHYAAAQG----CLQAVQILC------EHKSPINL- 147
Query: 236 PNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLE 294
+ G P LA G++ + L+ + L EI SS ++L++
Sbjct: 148 KDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIK 206
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 59.3 bits (142), Expect = 1e-08
Identities = 50/162 (30%), Positives = 71/162 (43%), Gaps = 19/162 (11%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
S L LAAK++ + + KLL+ + C + G+TALH AA L+A +L E
Sbjct: 91 SALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHK---- 145
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P+ + +G L +AV N + + LL A V++R G
Sbjct: 146 -SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKS-------------GRTA 191
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPN 208
L A + S V LI+ GAD+ DSLG LH L N
Sbjct: 192 LMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSEN 233
Score = 55.1 bits (131), Expect = 2e-07
Identities = 47/192 (24%), Positives = 81/192 (42%), Gaps = 27/192 (14%)
Query: 29 WAQSRDEQNLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAAL 88
W +++++ K + LL A ++ D + + LL + + + G+TA H+AA
Sbjct: 8 WLSAKEKKTNEWNKN--DDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAA 65
Query: 89 YDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVS---- 144
++E V++ ++ + T G +ALH+A N + +R LL +
Sbjct: 66 KGHVECLRVMITHGVDVTAQDTT-----GHSALHLAAKNSHHECIRKLLQSKCPAESVDS 120
Query: 145 --------ARATG-------TAFRRSPCNLIYF-GEHPLSFAACVNSEEIVRLLIEHGAD 188
A A G +SP NL G PL A EI L++HGAD
Sbjct: 121 SGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGAD 180
Query: 189 IRAQDSLGNTVL 200
+ +++ G T L
Sbjct: 181 VNSRNKSGRTAL 192
Score = 38.1 bits (87), Expect = 0.029
Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 12/95 (12%)
Query: 108 EPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPL 167
E T+E + L AV N + V +LL ++ + + + G+
Sbjct: 13 EKKTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSE------------GKTAF 60
Query: 168 SFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
AA E +R++I HG D+ AQD+ G++ LH+
Sbjct: 61 HLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHL 95
Score = 36.6 bits (83), Expect = 0.084
Identities = 41/179 (22%), Positives = 69/179 (38%), Gaps = 24/179 (13%)
Query: 116 EGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 175
EG+TA H+A ++ +R ++ V+A+ T G L AA +
Sbjct: 55 EGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT-------------GHSALHLAAKNSH 101
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLV 235
E +R L++ + DS G T LH Q Q +L +H P++L
Sbjct: 102 HECIRKLLQSKCPAESVDSSGKTALHYAAAQG----CLQAVQILC------EHKSPINL- 150
Query: 236 PNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLE 294
+ G P LA G++ + L+ + L EI SS ++L++
Sbjct: 151 KDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIK 209
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 59.3 bits (142), Expect = 1e-08
Identities = 50/162 (30%), Positives = 71/162 (43%), Gaps = 19/162 (11%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
S L LAAK++ + + KLL+ + C + G+TALH AA L+A +L E
Sbjct: 80 SALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHK---- 134
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P+ + +G L +AV N + + LL A V++R G
Sbjct: 135 -SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKS-------------GRTA 180
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPN 208
L A + S V LI+ GAD+ DSLG LH L N
Sbjct: 181 LMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSEN 222
Score = 54.7 bits (130), Expect = 3e-07
Identities = 45/172 (26%), Positives = 73/172 (42%), Gaps = 25/172 (14%)
Query: 49 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 108
LL A ++ D + + LL + + + G+TA H+AA ++E V++ ++ +
Sbjct: 15 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQ 74
Query: 109 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVS------------ARATG------- 149
T G +ALH+A N + +R LL + A A G
Sbjct: 75 DTT-----GHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQI 129
Query: 150 TAFRRSPCNLIYF-GEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVL 200
+SP NL G PL A EI L++HGAD+ +++ G T L
Sbjct: 130 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTAL 181
Score = 38.1 bits (87), Expect = 0.029
Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 12/95 (12%)
Query: 108 EPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPL 167
E T+E + L AV N + V +LL ++ + + + G+
Sbjct: 2 EAKTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSE------------GKTAF 49
Query: 168 SFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
AA E +R++I HG D+ AQD+ G++ LH+
Sbjct: 50 HLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHL 84
Score = 36.6 bits (83), Expect = 0.084
Identities = 41/179 (22%), Positives = 69/179 (38%), Gaps = 24/179 (13%)
Query: 116 EGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 175
EG+TA H+A ++ +R ++ V+A+ T G L AA +
Sbjct: 44 EGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT-------------GHSALHLAAKNSH 90
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLV 235
E +R L++ + DS G T LH Q Q +L +H P++L
Sbjct: 91 HECIRKLLQSKCPAESVDSSGKTALHYAAAQG----CLQAVQILC------EHKSPINL- 139
Query: 236 PNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLE 294
+ G P LA G++ + L+ + L EI SS ++L++
Sbjct: 140 KDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIK 198
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 59.3 bits (142), Expect = 1e-08
Identities = 50/162 (30%), Positives = 71/162 (43%), Gaps = 19/162 (11%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
S L LAAK++ + + KLL+ + C + G+TALH AA L+A +L E
Sbjct: 88 SALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHK---- 142
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P+ + +G L +AV N + + LL A V++R G
Sbjct: 143 -SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKS-------------GRTA 188
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPN 208
L A + S V LI+ GAD+ DSLG LH L N
Sbjct: 189 LMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSEN 230
Score = 54.7 bits (130), Expect = 3e-07
Identities = 45/172 (26%), Positives = 73/172 (42%), Gaps = 25/172 (14%)
Query: 49 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 108
LL A ++ D + + LL + + + G+TA H+AA ++E V++ ++ +
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQ 82
Query: 109 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVS------------ARATG------- 149
T G +ALH+A N + +R LL + A A G
Sbjct: 83 DTT-----GHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQI 137
Query: 150 TAFRRSPCNLIYF-GEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVL 200
+SP NL G PL A EI L++HGAD+ +++ G T L
Sbjct: 138 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTAL 189
Score = 37.0 bits (84), Expect = 0.065
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 12/92 (13%)
Query: 111 TSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFA 170
T+E + L AV N + V +LL ++ + + + G+ A
Sbjct: 13 TNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSE------------GKTAFHLA 60
Query: 171 ACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
A E +R++I HG D+ AQD+ G++ LH+
Sbjct: 61 AAKGHVECLRVMITHGVDVTAQDTTGHSALHL 92
Score = 36.6 bits (83), Expect = 0.084
Identities = 41/179 (22%), Positives = 69/179 (38%), Gaps = 24/179 (13%)
Query: 116 EGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 175
EG+TA H+A ++ +R ++ V+A+ T G L AA +
Sbjct: 52 EGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT-------------GHSALHLAAKNSH 98
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLV 235
E +R L++ + DS G T LH Q Q +L +H P++L
Sbjct: 99 HECIRKLLQSKCPAESVDSSGKTALHYAAAQG----CLQAVQILC------EHKSPINL- 147
Query: 236 PNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLE 294
+ G P LA G++ + L+ + L EI SS ++L++
Sbjct: 148 KDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIK 206
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 59.3 bits (142), Expect = 1e-08
Identities = 50/162 (30%), Positives = 71/162 (43%), Gaps = 19/162 (11%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
S L LAAK++ + + KLL+ + C + G+TALH AA L+A +L E
Sbjct: 88 SALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHK---- 142
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P+ + +G L +AV N + + LL A V++R G
Sbjct: 143 -SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKS-------------GRTA 188
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPN 208
L A + S V LI+ GAD+ DSLG LH L N
Sbjct: 189 LMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSEN 230
Score = 54.7 bits (130), Expect = 3e-07
Identities = 45/172 (26%), Positives = 73/172 (42%), Gaps = 25/172 (14%)
Query: 49 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 108
LL A ++ D + + LL + + + G+TA H+AA ++E V++ ++ +
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQ 82
Query: 109 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVS------------ARATG------- 149
T G +ALH+A N + +R LL + A A G
Sbjct: 83 DTT-----GHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQI 137
Query: 150 TAFRRSPCNLIYF-GEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVL 200
+SP NL G PL A EI L++HGAD+ +++ G T L
Sbjct: 138 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTAL 189
Score = 37.0 bits (84), Expect = 0.065
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 12/92 (13%)
Query: 111 TSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFA 170
T+E + L AV N + V +LL ++ + + + G+ A
Sbjct: 13 TNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSE------------GKTAFHLA 60
Query: 171 ACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
A E +R++I HG D+ AQD+ G++ LH+
Sbjct: 61 AAKGHVECLRVMITHGVDVTAQDTTGHSALHL 92
Score = 36.6 bits (83), Expect = 0.084
Identities = 41/179 (22%), Positives = 69/179 (38%), Gaps = 24/179 (13%)
Query: 116 EGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 175
EG+TA H+A ++ +R ++ V+A+ T G L AA +
Sbjct: 52 EGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT-------------GHSALHLAAKNSH 98
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLV 235
E +R L++ + DS G T LH Q Q +L +H P++L
Sbjct: 99 HECIRKLLQSKCPAESVDSSGKTALHYAAAQG----CLQAVQILC------EHKSPINL- 147
Query: 236 PNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLE 294
+ G P LA G++ + L+ + L EI SS ++L++
Sbjct: 148 KDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIK 206
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 59.3 bits (142), Expect = 1e-08
Identities = 50/162 (30%), Positives = 71/162 (43%), Gaps = 19/162 (11%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
S L LAAK++ + + KLL+ + C + G+TALH AA L+A +L E
Sbjct: 88 SALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHK---- 142
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P+ + +G L +AV N + + LL A V++R G
Sbjct: 143 -SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKS-------------GRTA 188
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPN 208
L A + S V LI+ GAD+ DSLG LH L N
Sbjct: 189 LMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSEN 230
Score = 54.7 bits (130), Expect = 3e-07
Identities = 45/172 (26%), Positives = 73/172 (42%), Gaps = 25/172 (14%)
Query: 49 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 108
LL A ++ D + + LL + + + G+TA H+AA ++E V++ ++ +
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQ 82
Query: 109 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVS------------ARATG------- 149
T G +ALH+A N + +R LL + A A G
Sbjct: 83 DTT-----GHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQI 137
Query: 150 TAFRRSPCNLIYF-GEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVL 200
+SP NL G PL A EI L++HGAD+ +++ G T L
Sbjct: 138 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTAL 189
Score = 37.0 bits (84), Expect = 0.065
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 12/92 (13%)
Query: 111 TSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFA 170
T+E + L AV N + V +LL ++ + + + G+ A
Sbjct: 13 TNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSE------------GKTAFHLA 60
Query: 171 ACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
A E +R++I HG D+ AQD+ G++ LH+
Sbjct: 61 AAKGHVECLRVMITHGVDVTAQDTTGHSALHL 92
Score = 36.6 bits (83), Expect = 0.084
Identities = 41/179 (22%), Positives = 69/179 (38%), Gaps = 24/179 (13%)
Query: 116 EGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 175
EG+TA H+A ++ +R ++ V+A+ T G L AA +
Sbjct: 52 EGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT-------------GHSALHLAAKNSH 98
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLV 235
E +R L++ + DS G T LH Q Q +L +H P++L
Sbjct: 99 HECIRKLLQSKCPAESVDSSGKTALHYAAAQG----CLQAVQILC------EHKSPINL- 147
Query: 236 PNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLE 294
+ G P LA G++ + L+ + L EI SS ++L++
Sbjct: 148 KDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIK 206
>gi|24233530 ankyrin repeat domain 44 [Homo sapiens]
Length = 919
Score = 58.9 bits (141), Expect = 2e-08
Identities = 45/158 (28%), Positives = 77/158 (48%), Gaps = 19/158 (12%)
Query: 44 IWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAP 103
+W +PL A +A+ L+K+ V+ R +T LH+AA ++ A V++
Sbjct: 48 MWLTPLHRAVASRSEEAVQVLIKHS-ADVNARDKNWQTPLHVAAANKAVKCAEVIIP--- 103
Query: 104 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFG 163
+ + G+TALH A +N ++ +V LLA+ A+++A F +
Sbjct: 104 --LLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINA------FDKKD------- 148
Query: 164 EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
L +AA + ++V LLI HGA++ +D G T LH
Sbjct: 149 RRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLH 186
Score = 50.4 bits (119), Expect = 6e-06
Identities = 68/292 (23%), Positives = 113/292 (38%), Gaps = 38/292 (13%)
Query: 46 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 105
+SPL LAA + QAL LL+ + R G TAL +AA + E L+ +
Sbjct: 543 KSPLHLAAYNGHHQALEVLLQ-SLVDLDIRDEKGRTALDLAAFKGHTECVEALINPGASI 601
Query: 106 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH 165
+ ++ +T LH +V+N + +R LL + A A ++P L H
Sbjct: 602 FVKDNVTK----RTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGH 657
Query: 166 -----------------------PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
L EE V++L+E I +DS G T LH
Sbjct: 658 IDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHY 717
Query: 203 LILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
+ + T+ ++ + LS + ++QG TP A GN + L+++
Sbjct: 718 AAARGHATWLSELLQMALSEED--------CCFKDNQGYTPLHWACYNGNENCIEVLLEQ 769
Query: 263 RKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREARQILDQTPVK 314
+ ++ P T I+ G+ SLL I + R +TP++
Sbjct: 770 KCFRKFIGNPFTP--LHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLR 819
Score = 40.8 bits (94), Expect = 0.004
Identities = 49/172 (28%), Positives = 68/172 (39%), Gaps = 27/172 (15%)
Query: 35 EQNLLQQKRIWESPLLLAAKDNDVQALNKLLKY----EDCKVHQRGAMGETALHIAALYD 90
E ++L + +PL AA L++LL+ EDC G T LH A
Sbjct: 701 EVSILCKDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDN--QGYTPLHWACYNG 758
Query: 91 NLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS--VSARAT 148
N VL+E + F + T LH A++N + N LL S VS R
Sbjct: 759 NENCIEVLLE---QKCFRKFIGNPF---TPLHCAIINDHGNCASLLLGAIDSSIVSCRDD 812
Query: 149 GTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVL 200
G PL AA + E ++LL+ H A + A D+ G T L
Sbjct: 813 K-------------GRTPLRAAAFADHVECLQLLLRHSAPVNAVDNSGKTAL 851
Score = 40.0 bits (92), Expect = 0.008
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 15/98 (15%)
Query: 116 EGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 175
E +T LH+A + ++ L+ A V+A+ PL A S
Sbjct: 15 EKRTPLHVAAFLGDAEIIELLILSGARVNAKDN-------------MWLTPLHRAVASRS 61
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFAC 213
EE V++LI+H AD+ A+D T LH + NK C
Sbjct: 62 EEAVQVLIKHSADVNARDKNWQTPLH--VAAANKAVKC 97
Score = 38.9 bits (89), Expect = 0.017
Identities = 39/156 (25%), Positives = 66/156 (42%), Gaps = 21/156 (13%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +AA+ +N L + + G LH+AAL + + L+ +
Sbjct: 316 TPLHVAARYGHELLINTL-RTSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSG---- 370
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAF-RRSPCNLIYFGEH 165
FE T + + G+T LH A N+ ++ L +++G F ++ C G
Sbjct: 371 FEIDTPDKF-GRTCLHAAAAGGNVECIKLL---------QSSGADFHKKDKC-----GRT 415
Query: 166 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
PL +AA + L+ GA++ D G T LH
Sbjct: 416 PLHYAAANCHFHCIETLVTTGANVNETDDWGRTALH 451
Score = 36.6 bits (83), Expect = 0.084
Identities = 41/157 (26%), Positives = 65/157 (41%), Gaps = 20/157 (12%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL AA + + + LL ++ + G TALHIA Y+ +A + + V
Sbjct: 183 TPLHAAASNGQINVVKHLLNL-GVEIDEINVYGNTALHIAC-YNGQDAVVNELIDYGANV 240
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARR-ASVSARATGTAFRRSPCNLIYFGEH 165
+P + G T LH A + + L LL A V+ ++ G+
Sbjct: 241 NQPNNN----GFTPLHFAAASTHGALCLELLVNNGADVNIQSKD-------------GKS 283
Query: 166 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
PL A + LI++G +I D GNT LH+
Sbjct: 284 PLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHV 320
Score = 34.7 bits (78), Expect = 0.32
Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 18/123 (14%)
Query: 79 GETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLA 138
G T LH+AA Y + L + + + S LH+A +N + + R LL+
Sbjct: 314 GNTPLHVAARYGHELLINTLRTSGADTAKCGIHSMF-----PLHLAALNAHSDCCRKLLS 368
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
+ FG L AA + E ++LL GAD +D G T
Sbjct: 369 SGFEIDTPDK-------------FGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRT 415
Query: 199 VLH 201
LH
Sbjct: 416 PLH 418
Score = 34.3 bits (77), Expect = 0.42
Identities = 51/210 (24%), Positives = 80/210 (38%), Gaps = 25/210 (11%)
Query: 54 KDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSE 113
K+ + + L D R G ++H AA Y + + +L+E E S+
Sbjct: 482 KEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGFEE---SD 538
Query: 114 LYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACV 173
++ LH+A N + + LL + R G L AA
Sbjct: 539 SGATKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEK-------------GRTALDLAAFK 585
Query: 174 NSEEIVRLLIEHGADIRAQDSL-GNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPL 232
E V LI GA I +D++ T LH ++ N C LLL D+ + +
Sbjct: 586 GHTECVEALINPGASIFVKDNVTKRTPLHASVI--NGHTLC--LRLLLEI---ADNPEAV 638
Query: 233 DLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
D V + +G TP LA G+ L++K
Sbjct: 639 D-VKDAKGQTPLMLAVAYGHIDAVSLLLEK 667
>gi|68131557 ankyrin repeat domain 28 [Homo sapiens]
Length = 1053
Score = 58.2 bits (139), Expect = 3e-08
Identities = 61/216 (28%), Positives = 96/216 (44%), Gaps = 30/216 (13%)
Query: 45 WESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 104
W +PL A +A+ LLK+ V+ R +T LHIAA ++ A EA
Sbjct: 74 WLTPLHRAVASCSEEAVQVLLKHS-ADVNARDKNWQTPLHIAAANKAVKCA----EALVP 128
Query: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164
L+ S+ G+TALH A + + +V+ LL+R A+++A F + I++
Sbjct: 129 LLSNVNVSDR-AGRTALHHAAFSGHGEMVKLLLSRGANINA------FDKKDRRAIHW-- 179
Query: 165 HPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDR 224
AA + E+V+LL+ HGA++ +D T LH + + Y L L D
Sbjct: 180 -----AAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLH--AAASSGMISVVKYLLDLGVDM 232
Query: 225 HGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLM 260
+ PN G TP +A G V+ L+
Sbjct: 233 N---------EPNAYGNTPLHVACYNGQDVVVNELI 259
Score = 49.7 bits (117), Expect = 1e-05
Identities = 58/251 (23%), Positives = 105/251 (41%), Gaps = 25/251 (9%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLM-EAAPEL 105
+PL LAA V+ ++ L+ + + + T +H AA + E +L+ A P+
Sbjct: 585 TPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQN 644
Query: 106 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH 165
+ GQT L ++V+N + + V +LL + A+V A+ +G
Sbjct: 645 AVDIQDGN---GQTPLMLSVLNGHTDCVYSLLNKGANVDAKDK-------------WGRT 688
Query: 166 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRH 225
L A EE V L++HGA +DS G T +H+ + AC +L + +
Sbjct: 689 ALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHL-------SAACGHIGVLGALLQS 741
Query: 226 GDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDS 285
+ ++ G T A G+ + L+++ Q T G S L+ D+
Sbjct: 742 AASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVF-QKTEGNAFSPLHCAVINDN 800
Query: 286 SGDEQSLLELI 296
G + L++ +
Sbjct: 801 EGAAEMLIDTL 811
Score = 47.4 bits (111), Expect = 5e-05
Identities = 40/149 (26%), Positives = 63/149 (42%), Gaps = 26/149 (17%)
Query: 75 RGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVR 134
R + G T +H++A ++ L+++A + P T++ + G TALH A N + V
Sbjct: 715 RDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNH-GYTALHWACYNGHETCVE 773
Query: 135 ALLARRASVSARATGTAFRRSPCNLIYF-----------------------GEHPLSFAA 171
LL + V + G AF C +I G PL AA
Sbjct: 774 LLLEQE--VFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAA 831
Query: 172 CVNSEEIVRLLIEHGADIRAQDSLGNTVL 200
+ E ++LL+ H A + + DS G T L
Sbjct: 832 FTDHVECLQLLLSHNAQVNSVDSTGKTPL 860
Score = 45.8 bits (107), Expect = 1e-04
Identities = 44/175 (25%), Positives = 65/175 (37%), Gaps = 22/175 (12%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL AA +LL V+ + G+T LH+ AL+ + ++++ +
Sbjct: 274 TPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVID 333
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
E G T LHIA + L+ L+ A + R G P
Sbjct: 334 CEDKN-----GNTPLHIAARYGHELLINTLITSGADTAKRGI-------------HGMFP 375
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLS 221
L AA + R L+ G DI D G T LH N + NLLL+
Sbjct: 376 LHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGN----LECLNLLLN 426
Score = 43.9 bits (102), Expect = 5e-04
Identities = 47/181 (25%), Positives = 79/181 (43%), Gaps = 25/181 (13%)
Query: 83 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 142
LH A + DN AA +L++ + S+ G+T LH A ++ ++ LL+ A
Sbjct: 792 LHCAVINDNEGAAEMLIDTLGASIVNATDSK---GRTPLHAAAFTDHVECLQLLLSHNAQ 848
Query: 143 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHG-ADIRAQDSLGNTVLH 201
V++ + G+ PL AA V +L+ A++ QD+ NT LH
Sbjct: 849 VNSVDST-------------GKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALH 895
Query: 202 ILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQ 261
+ + ++T A LL ++ D + L N TP +A G T++ Q L+
Sbjct: 896 LACSKGHETSA------LLILEKITD--RNLINATNAALQTPLHVAARNGLTMVVQELLG 947
Query: 262 K 262
K
Sbjct: 948 K 948
Score = 37.7 bits (86), Expect = 0.038
Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 2/100 (2%)
Query: 46 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 105
++PL++AA++ + L+ ++ + TALH+A + +A++++E +
Sbjct: 857 KTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDR 916
Query: 106 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSA 145
T+ QT LH+A N +V+ LL + ASV A
Sbjct: 917 NLINATNAAL--QTPLHVAARNGLTMVVQELLGKGASVLA 954
Score = 37.4 bits (85), Expect = 0.049
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 15/98 (15%)
Query: 116 EGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 175
E +T LH A + ++ L+ A V+A+ + PL A S
Sbjct: 40 EKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLT-------------PLHRAVASCS 86
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFAC 213
EE V++L++H AD+ A+D T LH I NK C
Sbjct: 87 EEAVQVLLKHSADVNARDKNWQTPLH--IAAANKAVKC 122
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 58.2 bits (139), Expect = 3e-08
Identities = 60/237 (25%), Positives = 97/237 (40%), Gaps = 41/237 (17%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME--AAPE 104
+PL +AAK ++ N LL+ + G G T LH+AA YDN + A++L++ A+P
Sbjct: 567 TPLHVAAKYGKLEVANLLLQ-KSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPH 625
Query: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSA------RATGTAFRRSPCN 158
+ G T LHIA M++ LL A +A + A + +
Sbjct: 626 AAAK-------NGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVD 678
Query: 159 LIYF--------------GEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILI 204
++ G PL AA + + +L+ GA + AQ +G T LH+
Sbjct: 679 MVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGC 738
Query: 205 LQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQ 261
N ++ N LL + + G TP A +G+T + L+Q
Sbjct: 739 HYGN----IKIVNFLLQHSAKVN-------AKTKNGYTPLHQAAQQGHTHIINVLLQ 784
Score = 54.3 bits (129), Expect = 4e-07
Identities = 45/154 (29%), Positives = 68/154 (44%), Gaps = 19/154 (12%)
Query: 49 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 108
L +AA+ +D +A LL+ D G T LHIAA Y N+ A +L+ A + F
Sbjct: 206 LHIAARKDDTKAAALLLQ-NDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFT 264
Query: 109 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 168
T LH+A N N+V+ LL R A + A+ G PL
Sbjct: 265 ARND-----ITPLHVASKRGNANMVKLLLDRGAKIDAKTRD-------------GLTPLH 306
Query: 169 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
A E++V +L++ A I ++ G + LH+
Sbjct: 307 CGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHM 340
Score = 52.8 bits (125), Expect = 1e-06
Identities = 49/192 (25%), Positives = 81/192 (42%), Gaps = 23/192 (11%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+P+ +AA V +++L+ + + GETALH+AA E L++ ++
Sbjct: 435 TPIHVAAFMGHVNIVSQLM-HHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV- 492
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
++ + QT LHI+ ++V+ LL + AS +A T G P
Sbjct: 493 ----EAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTS-------------GYTP 535
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 226
L +A E++ L++HGA + G T LH+ K ++ NLLL
Sbjct: 536 LHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAA----KYGKLEVANLLLQKSASP 591
Query: 227 DHLQPLDLVPNH 238
D L P H
Sbjct: 592 DAAGKSGLTPLH 603
Score = 48.1 bits (113), Expect = 3e-05
Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 23/155 (14%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL +A + Q ++ LL+ + +G + ALHIAA D+ +AA +L++
Sbjct: 175 TPLAVALQQGHDQVVSLLLENDT-----KGKVRLPALHIAARKDDTKAAALLLQNDNNAD 229
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
E + G T LHIA N+N+ LL R A+V A P
Sbjct: 230 VESKS-----GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDI-------------TP 271
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 201
L A+ + +V+LL++ GA I A+ G T LH
Sbjct: 272 LHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLH 306
Score = 48.1 bits (113), Expect = 3e-05
Identities = 49/215 (22%), Positives = 88/215 (40%), Gaps = 30/215 (13%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
+PL A+ Q + LL + + G + LH+A D+L +L++
Sbjct: 303 TPLHCGARSGHEQVVEMLLD-RAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNV--- 358
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
P+ + TALH+A + + + LL ++A+ +A+A G P
Sbjct: 359 --PVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALN-------------GFTP 403
Query: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 226
L A N +++ LL++HGA I+A G T +H+ + Q+ + HG
Sbjct: 404 LHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMH-------HG 456
Query: 227 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQ 261
N +G T +A G + ++L+Q
Sbjct: 457 ASPN----TTNVRGETALHMAARSGQAEVVRYLVQ 487
Score = 44.3 bits (103), Expect = 4e-04
Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 22/148 (14%)
Query: 79 GETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLA 138
G ALH+A+ ++E L++ + + +G TALHIA + +V+ L+
Sbjct: 74 GLNALHLASKEGHVEVVSELLQREANV-----DAATKKGNTALHIASLAGQAEVVKVLVT 128
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
A+V+A++ G PL AA N E+V+ L+++GA G T
Sbjct: 129 NGANVNAQSQN-------------GFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFT 175
Query: 199 VLHILILQPNKTFACQMYNLLLSYDRHG 226
L + + Q + Q+ +LLL D G
Sbjct: 176 PLAVALQQGHD----QVVSLLLENDTKG 199
Score = 42.7 bits (99), Expect = 0.001
Identities = 47/176 (26%), Positives = 71/176 (40%), Gaps = 26/176 (14%)
Query: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
SPL +A + + + + LL++ + V TALH+AA + + A VL++
Sbjct: 336 SPLHMATQGDHLNCVQLLLQH-NVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKAN-- 392
Query: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATG-------TAFR------ 153
++ G T LHIA + ++ LL AS+ A AF
Sbjct: 393 ---PNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIV 449
Query: 154 -------RSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
SP GE L AA E+VR L++ GA + A+ T LHI
Sbjct: 450 SQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHI 505
>gi|164664508 B-cell CLL/lymphoma 3 [Homo sapiens]
Length = 454
Score = 56.2 bits (134), Expect = 1e-07
Identities = 39/123 (31%), Positives = 62/123 (50%), Gaps = 13/123 (10%)
Query: 79 GETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLA 138
G+TA H+A + + L+++A + + + Y+G TALH+AV + V+ LL
Sbjct: 205 GQTAAHLACEHRSPTCLRALLDSAAPGTLD-LEARNYDGLTALHVAVNTECQETVQLLLE 263
Query: 139 RRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 198
R A + A I G PL A NS +V+LL++HGA++ AQ G++
Sbjct: 264 RGADIDAVD------------IKSGRSPLIHAVENNSLSMVQLLLQHGANVNAQMYSGSS 311
Query: 199 VLH 201
LH
Sbjct: 312 ALH 314
Score = 39.3 bits (90), Expect = 0.013
Identities = 56/179 (31%), Positives = 74/179 (41%), Gaps = 45/179 (25%)
Query: 79 GETALHIAALYDNLEAAMVLMEAAPELVFEPMTSEL--YEG--QTALHIAVVNQNMNLVR 134
G+T LHIA + NL A L+ +F+ EL Y QT LH+AV+ ++VR
Sbjct: 135 GDTPLHIAVVQGNLPAVHRLVN-----LFQQGGRELDIYNNLRQTPLHLAVITTLPSVVR 189
Query: 135 ALLARRASVSA--RATGTAF-----RRSPCNL-----------------IYFGEHPLSFA 170
L+ AS A R TA RSP L Y G L A
Sbjct: 190 LLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVA 249
Query: 171 ACVNSEEIVRLLIEHGADIRAQD--SLGNTVLHI----------LILQPNKTFACQMYN 217
+E V+LL+E GADI A D S + ++H L+LQ QMY+
Sbjct: 250 VNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQLLLQHGANVNAQMYS 308
Score = 35.0 bits (79), Expect = 0.25
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 15/90 (16%)
Query: 116 EGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFG---EHPLSFAAC 172
+G T LHIAVV N+ V L+ F++ L + + PL A
Sbjct: 134 DGDTPLHIAVVQGNLPAVHRLV------------NLFQQGGRELDIYNNLRQTPLHLAVI 181
Query: 173 VNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
+VRLL+ GA A D G T H+
Sbjct: 182 TTLPSVVRLLVTAGASPMALDRHGQTAAHL 211
>gi|89363047 death-associated protein kinase 1 [Homo sapiens]
Length = 1430
Score = 56.2 bits (134), Expect = 1e-07
Identities = 56/203 (27%), Positives = 83/203 (40%), Gaps = 34/203 (16%)
Query: 52 AAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMT 111
AA+ V L K L C + + GE ALH+AA Y + + A +L +
Sbjct: 419 AARHGHVDTL-KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDK- 476
Query: 112 SELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAA 171
E +T LH A + ++ +AL +V+ + GE PL A+
Sbjct: 477 ----EEETPLHCAAWHGYYSVAKALCEAGCNVNIKNRE-------------GETPLLTAS 519
Query: 172 CVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM--YNLLLSYDRHGDHL 229
+IV L EHGAD+ A D G+ LH+ + + CQM LLS D+
Sbjct: 520 ARGYHDIVECLAEHGADLNACDKDGHIALHLAVRR------CQMEVIKTLLSQGCFVDY- 572
Query: 230 QPLDLVPNHQGLTPFKLAGVEGN 252
+ G TP +A +GN
Sbjct: 573 ------QDRHGNTPLHVACKDGN 589
Score = 38.5 bits (88), Expect = 0.022
Identities = 33/100 (33%), Positives = 47/100 (47%), Gaps = 6/100 (6%)
Query: 49 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 108
L LA + ++ + LL + C V + G T LH+A N+ + L EA L
Sbjct: 548 LHLAVRRCQMEVIKTLLS-QGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDI- 605
Query: 109 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARAT 148
S Y G+T LH+A N +++VR L ASV A T
Sbjct: 606 ---SNKY-GRTPLHLAANNGILDVVRYLCLMGASVEALTT 641
Score = 35.0 bits (79), Expect = 0.25
Identities = 53/219 (24%), Positives = 83/219 (37%), Gaps = 26/219 (11%)
Query: 37 NLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAM 96
N+ + R E+PLL A+ + + L ++ G ALH+A +E
Sbjct: 503 NVNIKNREGETPLLTASA-RGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIK 561
Query: 97 VLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSP 156
L+ + ++ G T LH+A + NM +V AL +
Sbjct: 562 TLLSQGCFVDYQDR-----HGNTPLHVACKDGNMPIVVALC----------------EAN 600
Query: 157 CNLIY---FGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFAC 213
CNL +G PL AA ++VR L GA + A + G T + + ++ A
Sbjct: 601 CNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAG 660
Query: 214 QMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGN 252
+ L R G +Q L N Q KL G G+
Sbjct: 661 LLARLRKDTHR-GLFIQQLRPTQNLQPRIKLKLFGHSGS 698
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.139 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,262,047
Number of Sequences: 37866
Number of extensions: 1122321
Number of successful extensions: 5426
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 154
Number of HSP's that attempted gapping in prelim test: 3544
Number of HSP's gapped (non-prelim): 1142
length of query: 725
length of database: 18,247,518
effective HSP length: 110
effective length of query: 615
effective length of database: 14,082,258
effective search space: 8660588670
effective search space used: 8660588670
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.