Guide to the Human Genome
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Search of human proteins with 21265104

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21265104 tetraspanin 7 [Homo sapiens]
         (249 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21265104 tetraspanin 7 [Homo sapiens]                              511   e-145
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]        301   3e-82
gi|4502679 CD63 antigen isoform A [Homo sapiens]                      141   5e-34
gi|91199546 CD63 antigen isoform B [Homo sapiens]                     136   1e-32
gi|87159824 CD151 antigen [Homo sapiens]                              133   1e-31
gi|87159822 CD151 antigen [Homo sapiens]                              133   1e-31
gi|21237751 CD151 antigen [Homo sapiens]                              133   1e-31
gi|21237748 CD151 antigen [Homo sapiens]                              133   1e-31
gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo ...   130   8e-31
gi|4504813 CD82 antigen isoform 1 [Homo sapiens]                      117   9e-27
gi|122937466 tetraspanin 11 [Homo sapiens]                            112   2e-25
gi|50511934 transmembrane 4 superfamily member 17 isoform b [Hom...   112   2e-25
gi|54859560 transmembrane 4 superfamily member 17 isoform a [Hom...   112   2e-25
gi|54859505 transmembrane 4 superfamily member 17 isoform c [Hom...   112   2e-25
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]       110   1e-24
gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]                   108   3e-24
gi|5729941 tetraspanin 9 [Homo sapiens]                               108   3e-24
gi|30425534 tetraspanin 33 [Homo sapiens]                             108   3e-24
gi|21264578 tetraspan 1 [Homo sapiens]                                105   4e-23
gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]       103   2e-22
gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]                   99   3e-21
gi|38787991 transmembrane 4 superfamily member 8 isoform 2 [Homo...    99   3e-21
gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]                    99   4e-21
gi|67782354 CD82 antigen isoform 2 [Homo sapiens]                      94   1e-19
gi|4502693 CD9 antigen [Homo sapiens]                                  93   2e-19
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]         91   7e-19
gi|68800005 tetraspanin 4 isoform a [Homo sapiens]                     86   3e-17
gi|4507543 tetraspanin 4 isoform a [Homo sapiens]                      86   3e-17
gi|68800018 tetraspanin 4 isoform a [Homo sapiens]                     86   3e-17
gi|68800024 tetraspanin 4 isoform a [Homo sapiens]                     86   3e-17

>gi|21265104 tetraspanin 7 [Homo sapiens]
          Length = 249

 Score =  511 bits (1317), Expect = e-145
 Identities = 249/249 (100%), Positives = 249/249 (100%)

Query: 1   MASRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPY 60
           MASRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPY
Sbjct: 1   MASRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPY 60

Query: 61  VLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTF 120
           VLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTF
Sbjct: 61  VLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTF 120

Query: 121 LRTYTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETD 180
           LRTYTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETD
Sbjct: 121 LRTYTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETD 180

Query: 181 CNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRF 240
           CNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRF
Sbjct: 181 CNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRF 240

Query: 241 ITANQYEMV 249
           ITANQYEMV
Sbjct: 241 ITANQYEMV 249


>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
          Length = 245

 Score =  301 bits (772), Expect = 3e-82
 Identities = 146/248 (58%), Positives = 185/248 (74%), Gaps = 8/248 (3%)

Query: 3   SRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVL 62
           SRR++TKPVITC K++L+IY+F+FWITGVILLAVG+WGK++L  Y SL+ E +TN P+VL
Sbjct: 5   SRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVL 64

Query: 63  IGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLR 122
           I TGT I++ G FGCFATCR S WMLKLYAMFL+LVFL ELVA I GFVFRHEIK++F  
Sbjct: 65  IATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKN 124

Query: 123 TYTDAMQTYNG-NDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETDC 181
            Y  A++ YN   D RS AVD +Q +L CCGV +Y +W+ + Y+ E G P SCC  E DC
Sbjct: 125 NYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLE-DC 183

Query: 182 NPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFI 241
            PQ        A KVN +GC+  V + +E+ MG++AG++FG+A  QLIG+ LA CLSR I
Sbjct: 184 TPQR------DADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAI 237

Query: 242 TANQYEMV 249
           T NQYE+V
Sbjct: 238 TNNQYEIV 245


>gi|4502679 CD63 antigen isoform A [Homo sapiens]
          Length = 238

 Score =  141 bits (356), Expect = 5e-34
 Identities = 73/237 (30%), Positives = 125/237 (52%), Gaps = 8/237 (3%)

Query: 14  CLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFG 73
           C+K LL +    F    V L+AVGV  +L L   I   A   +  P V+I  G  + +  
Sbjct: 9   CVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVA 68

Query: 74  LFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTYNG 133
             GC   C+ +  ++  +A+FLSL+ L E+ A I+G+VFR ++   F   +   M+ Y  
Sbjct: 69  FVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPK 128

Query: 134 NDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNET-DCNPQDLHNLTVA 192
           N+  +  +D +Q    CCG  NYT+W   P   ++ +P SCC+N T  C       +   
Sbjct: 129 NNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGC------GINFN 182

Query: 193 ATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITANQYEMV 249
              ++++GC + +  ++  N+ ++A  A GIAF +++G++ ACCL + I +  YE++
Sbjct: 183 EKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRSG-YEVM 238


>gi|91199546 CD63 antigen isoform B [Homo sapiens]
          Length = 236

 Score =  136 bits (343), Expect = 1e-32
 Identities = 73/237 (30%), Positives = 124/237 (52%), Gaps = 10/237 (4%)

Query: 14  CLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFG 73
           C+K LL +    F    V L+AVGV  +L L   I   A   +  P V+I  G  + +  
Sbjct: 9   CVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVA 68

Query: 74  LFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTYNG 133
             GC   C+ +  ++  +A+FLSL+ L E+ A I+G+VFR ++   F   +   M+ Y  
Sbjct: 69  FVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPK 128

Query: 134 NDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNET-DCNPQDLHNLTVA 192
           N+  +  +D +Q    CCG  NYT+W   P   ++ +P SCC+N T  C       +   
Sbjct: 129 NNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGC------GINFN 182

Query: 193 ATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITANQYEMV 249
              ++++GC + +  ++  N+ ++A  A GIAF  ++G++ ACCL + I +  YE++
Sbjct: 183 EKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCLVKSIRSG-YEVM 236


>gi|87159824 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  133 bits (335), Expect = 1e-31
 Identities = 75/242 (30%), Positives = 122/242 (50%), Gaps = 12/242 (4%)

Query: 14  CLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAP-YVLIGTGTTIVVF 72
           CLK LL  Y+  FW+ G+ ++AVG+W       YISL+A  +  A  Y+L+  GT ++V 
Sbjct: 15  CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVT 74

Query: 73  GLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAM-QTY 131
           G+ GC AT +    +L+LY + L ++FL E++AGI  + +  ++         D M + Y
Sbjct: 75  GVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRY 134

Query: 132 N--GNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHG-----IPPSCCMNETDCNPQ 184
           +  G++  + AVD +Q+   CCG  N  +W  S +          +P SCC        Q
Sbjct: 135 HQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQ 194

Query: 185 DLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITAN 244
             H   +      + GC   + +F++ ++ +I  V  GIA  Q+ GM+  CCL R +   
Sbjct: 195 RDHASNIYKV---EGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLE 251

Query: 245 QY 246
            Y
Sbjct: 252 HY 253


>gi|87159822 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  133 bits (335), Expect = 1e-31
 Identities = 75/242 (30%), Positives = 122/242 (50%), Gaps = 12/242 (4%)

Query: 14  CLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAP-YVLIGTGTTIVVF 72
           CLK LL  Y+  FW+ G+ ++AVG+W       YISL+A  +  A  Y+L+  GT ++V 
Sbjct: 15  CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVT 74

Query: 73  GLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAM-QTY 131
           G+ GC AT +    +L+LY + L ++FL E++AGI  + +  ++         D M + Y
Sbjct: 75  GVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRY 134

Query: 132 N--GNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHG-----IPPSCCMNETDCNPQ 184
           +  G++  + AVD +Q+   CCG  N  +W  S +          +P SCC        Q
Sbjct: 135 HQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQ 194

Query: 185 DLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITAN 244
             H   +      + GC   + +F++ ++ +I  V  GIA  Q+ GM+  CCL R +   
Sbjct: 195 RDHASNIYKV---EGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLE 251

Query: 245 QY 246
            Y
Sbjct: 252 HY 253


>gi|21237751 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  133 bits (335), Expect = 1e-31
 Identities = 75/242 (30%), Positives = 122/242 (50%), Gaps = 12/242 (4%)

Query: 14  CLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAP-YVLIGTGTTIVVF 72
           CLK LL  Y+  FW+ G+ ++AVG+W       YISL+A  +  A  Y+L+  GT ++V 
Sbjct: 15  CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVT 74

Query: 73  GLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAM-QTY 131
           G+ GC AT +    +L+LY + L ++FL E++AGI  + +  ++         D M + Y
Sbjct: 75  GVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRY 134

Query: 132 N--GNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHG-----IPPSCCMNETDCNPQ 184
           +  G++  + AVD +Q+   CCG  N  +W  S +          +P SCC        Q
Sbjct: 135 HQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQ 194

Query: 185 DLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITAN 244
             H   +      + GC   + +F++ ++ +I  V  GIA  Q+ GM+  CCL R +   
Sbjct: 195 RDHASNIYKV---EGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLE 251

Query: 245 QY 246
            Y
Sbjct: 252 HY 253


>gi|21237748 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  133 bits (335), Expect = 1e-31
 Identities = 75/242 (30%), Positives = 122/242 (50%), Gaps = 12/242 (4%)

Query: 14  CLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAP-YVLIGTGTTIVVF 72
           CLK LL  Y+  FW+ G+ ++AVG+W       YISL+A  +  A  Y+L+  GT ++V 
Sbjct: 15  CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVT 74

Query: 73  GLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAM-QTY 131
           G+ GC AT +    +L+LY + L ++FL E++AGI  + +  ++         D M + Y
Sbjct: 75  GVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRY 134

Query: 132 N--GNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHG-----IPPSCCMNETDCNPQ 184
           +  G++  + AVD +Q+   CCG  N  +W  S +          +P SCC        Q
Sbjct: 135 HQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQ 194

Query: 185 DLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITAN 244
             H   +      + GC   + +F++ ++ +I  V  GIA  Q+ GM+  CCL R +   
Sbjct: 195 RDHASNIYKV---EGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLE 251

Query: 245 QY 246
            Y
Sbjct: 252 HY 253


>gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo
           sapiens]
          Length = 253

 Score =  130 bits (328), Expect = 8e-31
 Identities = 80/231 (34%), Positives = 119/231 (51%), Gaps = 12/231 (5%)

Query: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAP-YVLIGTGTTIV 70
           IT  KT+L+  + +FW    IL  VG +  +T   Y     +  T  P  V+I  G  + 
Sbjct: 6   ITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLF 65

Query: 71  VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130
           + GL GC AT R S   L  + + L LVF+ E+V  + G+V+R ++++   R+     +T
Sbjct: 66  IIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKT 125

Query: 131 YNGN--DERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLE---HGIPPSCCM-NETDCNPQ 184
           YNG   D  SRA+D+VQR L CCG+ NY++W  + +F E     +P SCC    ++CN  
Sbjct: 126 YNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGS 185

Query: 185 DLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLAC 235
             H   + A     +GC  LV   ++  M  +   A   A  QL+GML AC
Sbjct: 186 LAHPSDLYA-----EGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 231


>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
          Length = 267

 Score =  117 bits (293), Expect = 9e-27
 Identities = 74/259 (28%), Positives = 127/259 (49%), Gaps = 21/259 (8%)

Query: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTN---APYVLIGTGTT 68
           I   K  L +++ +F+I G ++L  GVW      ++IS++  +S++     YV IG G  
Sbjct: 6   IKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAV 65

Query: 69  IVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAM 128
            ++ G  GC         +L LY  FL L+ +A++ AG   +    ++K       T+ +
Sbjct: 66  TMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELI 125

Query: 129 QTYNGNDERSR--AVDHVQRSLSCCGVQNYTNWSTSPYFL---EHGIPPSCCMNETDCNP 183
           + YN + E S   A D+VQ  + CCG  ++ NW+ +   +   E   P SC +   + N 
Sbjct: 126 RDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNS 185

Query: 184 QDLH--------NLTVAATK-----VNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIG 230
             +         N T +        V Q+GC + V ++++ N+GII GV  G+A  +L+G
Sbjct: 186 LSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLG 245

Query: 231 MLLACCLSRFITANQYEMV 249
           M+L+ CL R + +  Y  V
Sbjct: 246 MVLSICLCRHVHSEDYSKV 264


>gi|122937466 tetraspanin 11 [Homo sapiens]
          Length = 253

 Score =  112 bits (281), Expect = 2e-25
 Identities = 71/246 (28%), Positives = 117/246 (47%), Gaps = 14/246 (5%)

Query: 11  VITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNA-PYVLIGTGTTI 69
           +I  LK LL +++F FW+ G  +LAVG+W  +    Y+S++A ++  A  Y+LI  G  +
Sbjct: 12  LIIYLKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGVLV 71

Query: 70  VVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQ 129
           +V G  G  A        L  Y   L ++FL ELVAG+   V+   + D  L+ + +   
Sbjct: 72  MVTGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDE-LKQHLNRTL 130

Query: 130 TYN----GNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFL-----EHGIPPSCCMNETD 180
             N    G  + + +VD +Q+   CCG  +  +W  S Y L        +P SCC     
Sbjct: 131 AENYGQPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTVVV 190

Query: 181 CNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRF 240
              Q  H   +      + GC   +  F+  ++ ++  V  G+A  Q+ GM+L CCL + 
Sbjct: 191 RCGQRAHPSNIYKV---EGGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHQR 247

Query: 241 ITANQY 246
           +  + Y
Sbjct: 248 LQRHFY 253


>gi|50511934 transmembrane 4 superfamily member 17 isoform b [Homo
           sapiens]
          Length = 329

 Score =  112 bits (281), Expect = 2e-25
 Identities = 67/241 (27%), Positives = 112/241 (46%), Gaps = 20/241 (8%)

Query: 14  CLKTLLIIYSFVFWITGVILLAVGVWG---KLTLGTYISLIAENSTNAPYVLIGTGTTIV 70
           C K  L  ++ VFW+ G + LA+G+W    K  L    +L      +  ++ +  G  + 
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMS 75

Query: 71  VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130
           V G  GC    R + ++LK +++FL L+F  EL  GI  FVF+  I+D       + ++ 
Sbjct: 76  VLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKA 135

Query: 131 YNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYF---------LEHGIPPSCCMNE--- 178
           Y  + +    +D  Q   SCCG +   +W+ + YF            G+P SCC+ +   
Sbjct: 136 YRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195

Query: 179 ----TDCNPQDLHNLTVAATK-VNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLL 233
               T C       L +     ++ KGC      +++ N+ ++AGV  GIA  Q+ G+ L
Sbjct: 196 DVLNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGICL 255

Query: 234 A 234
           A
Sbjct: 256 A 256


>gi|54859560 transmembrane 4 superfamily member 17 isoform a [Homo
           sapiens]
          Length = 332

 Score =  112 bits (281), Expect = 2e-25
 Identities = 67/244 (27%), Positives = 115/244 (47%), Gaps = 23/244 (9%)

Query: 14  CLKTLLIIYSFVFWITGVILLAVGVWG---KLTLGTYISLIAENSTNAPYVLIGTGTTIV 70
           C K  L  ++ VFW+ G + LA+G+W    K  L    +L      +  ++ +  G  + 
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMS 75

Query: 71  VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130
           V G  GC    R + ++LK +++FL L+F  EL  GI  FVF+  I+D       + ++ 
Sbjct: 76  VLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKA 135

Query: 131 YNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYF---------LEHGIPPSCCMN---E 178
           Y  + +    +D  Q   SCCG +   +W+ + YF            G+P SCC+    E
Sbjct: 136 YRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195

Query: 179 TDCNPQDLHNLTVAATK--------VNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIG 230
              N Q  +++ +   +        ++ KGC      +++ N+ ++AGV  GIA  Q+ G
Sbjct: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255

Query: 231 MLLA 234
           + LA
Sbjct: 256 ICLA 259


>gi|54859505 transmembrane 4 superfamily member 17 isoform c [Homo
           sapiens]
          Length = 266

 Score =  112 bits (281), Expect = 2e-25
 Identities = 67/244 (27%), Positives = 115/244 (47%), Gaps = 23/244 (9%)

Query: 14  CLKTLLIIYSFVFWITGVILLAVGVWG---KLTLGTYISLIAENSTNAPYVLIGTGTTIV 70
           C K  L  ++ VFW+ G + LA+G+W    K  L    +L      +  ++ +  G  + 
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMS 75

Query: 71  VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130
           V G  GC    R + ++LK +++FL L+F  EL  GI  FVF+  I+D       + ++ 
Sbjct: 76  VLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKA 135

Query: 131 YNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYF---------LEHGIPPSCCMN---E 178
           Y  + +    +D  Q   SCCG +   +W+ + YF            G+P SCC+    E
Sbjct: 136 YRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195

Query: 179 TDCNPQDLHNLTVAATK--------VNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIG 230
              N Q  +++ +   +        ++ KGC      +++ N+ ++AGV  GIA  Q+ G
Sbjct: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255

Query: 231 MLLA 234
           + LA
Sbjct: 256 ICLA 259


>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
          Length = 268

 Score =  110 bits (274), Expect = 1e-24
 Identities = 64/254 (25%), Positives = 112/254 (44%), Gaps = 20/254 (7%)

Query: 1   MASRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWG---KLTLGTYISLIAENSTN 57
           M+ +  +   V  C+K  +  ++ +FW  G+  L +G+W    K  L    S+      +
Sbjct: 1   MSGKHYKGPEVSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFD 60

Query: 58  APYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIK 117
             ++ +  G  + + G  GC    R + ++LK +++FL ++F  EL AG+  FVF+  IK
Sbjct: 61  PVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIK 120

Query: 118 DTFLRTYTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYF---------LEH 168
           D       + ++ Y  + +    +D  Q    CCG     +W+ + YF            
Sbjct: 121 DQLYFFINNNIRAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERC 180

Query: 169 GIPPSCCMNE-------TDCNPQDLHNLTV-AATKVNQKGCYDLVTSFMETNMGIIAGVA 220
           G+P SCC  +       T C         V     +  KGC      +++ N+ I+AG+ 
Sbjct: 181 GVPFSCCTKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIF 240

Query: 221 FGIAFSQLIGMLLA 234
            GIA  Q+ G+ LA
Sbjct: 241 IGIALLQIFGICLA 254


>gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]
          Length = 248

 Score =  108 bits (271), Expect = 3e-24
 Identities = 64/246 (26%), Positives = 118/246 (47%), Gaps = 20/246 (8%)

Query: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENST--NAPYVLIGTGTTI 69
           ++C+K L+ +++F  ++ G  LLA+G+W  +    +  ++A N       Y+L+  G  +
Sbjct: 6   LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLL 65

Query: 70  VVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEI-KDTFLRTYTDAM 128
            + G  GC    R +  +L  + +F+ ++FLAEL A I  F+FR  + ++ F +  T   
Sbjct: 66  FLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHY 125

Query: 129 QTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFL-----EHGIPPSCCMNETDCNP 183
           Q  N  D  S   + V  +  CCGV    ++  +  F         +P +CC  E    P
Sbjct: 126 QGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRRE----P 181

Query: 184 QDLHNLTVAATK--------VNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLAC 235
           Q    + ++  +        +N++GCY ++ +  ET + +   +A G+   +L  M+ A 
Sbjct: 182 QSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAM 241

Query: 236 CLSRFI 241
           CL R I
Sbjct: 242 CLFRGI 247


>gi|5729941 tetraspanin 9 [Homo sapiens]
          Length = 239

 Score =  108 bits (271), Expect = 3e-24
 Identities = 65/242 (26%), Positives = 119/242 (49%), Gaps = 15/242 (6%)

Query: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAE-NSTNAPYVLIGTGTTIV 70
           + CLK ++ +++ +FW+ G  LL VG+W  ++ G + +      S +A  ++I  GT ++
Sbjct: 6   LCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVM 65

Query: 71  VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130
           V G  GC    + +  +L  + + L ++ LAEL+  I  FV+  ++ +   +   + +  
Sbjct: 66  VTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLLL 125

Query: 131 YN--GNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCM-NETDCNPQDLH 187
           Y+   N     A + +Q  + CCGV +YT+W   P   E+ +P  CCM N   C      
Sbjct: 126 YHTENNVGLKNAWNIIQAEMRCCGVTDYTDW--YPVLGENTVPDRCCMENSQGCGRN--- 180

Query: 188 NLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFI--TANQ 245
               A T + + GCY+ V  + + N  ++  V   I   Q++GM  +  L + I  T  +
Sbjct: 181 ----ATTPLWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFSMTLFQHIHRTGKK 236

Query: 246 YE 247
           Y+
Sbjct: 237 YD 238


>gi|30425534 tetraspanin 33 [Homo sapiens]
          Length = 283

 Score =  108 bits (271), Expect = 3e-24
 Identities = 65/237 (27%), Positives = 119/237 (50%), Gaps = 18/237 (7%)

Query: 15  LKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFGL 74
           +K LL  ++ +FW+  ++++AVGV+ +L      +L A  + +   +LI  G  + +   
Sbjct: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAAL-ACLAVDPAILLIVVGVLMFLLTF 80

Query: 75  FGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTYNGN 134
            GC  + R +  +L+ +++ L+ VFL +L AGI GFVF  + +        +A+  Y  +
Sbjct: 81  CGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDD 140

Query: 135 DERSRAVDHVQRSLSCCGVQNYTNWSTSPYF---------LEHGIPPSCCMNETD----- 180
            +    +D  Q+  SCCG  +Y +WS + YF             +P SCC+   D     
Sbjct: 141 LDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVIN 200

Query: 181 --CNP-QDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLA 234
             C       +   A+  +   GC D + +++ +N+ ++ GVA G+A  QL+G+LL+
Sbjct: 201 TMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLS 257


>gi|21264578 tetraspan 1 [Homo sapiens]
          Length = 241

 Score =  105 bits (262), Expect = 4e-23
 Identities = 65/238 (27%), Positives = 112/238 (47%), Gaps = 23/238 (9%)

Query: 15  LKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENST------NAPYVLIGTGTT 68
           +KT++I+++ + ++ G  LLAVG+W  +   +++ +    S+      N  Y LI  G  
Sbjct: 7   IKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVV 66

Query: 69  IVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAM 128
           +   G  GC+     S   L  +   L L+F+AE+ A +   V+    +         A+
Sbjct: 67  VFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAI 126

Query: 129 QT-YNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEH-GIPPSCC-------MNET 179
           +  Y   ++ ++  +   + L CCG  NYT++  SPYF E+   PP CC        NET
Sbjct: 127 KKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVTNTANET 186

Query: 180 DCNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCL 237
            C  Q  H+  V       +GC++ +   + TN   + GVA GI   +L  M+++  L
Sbjct: 187 -CTKQKAHDQKV-------EGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYL 236


>gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]
          Length = 294

 Score =  103 bits (256), Expect = 2e-22
 Identities = 65/234 (27%), Positives = 114/234 (48%), Gaps = 17/234 (7%)

Query: 15  LKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAP-YVLIGTGTTIVVFG 73
           LK  LIIYS VFW+ G ++L+VG++ ++    Y +L  E++  AP  +LI  G  + +  
Sbjct: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTL--ESAFLAPAIILILLGVVMFMVS 77

Query: 74  LFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTYNG 133
             G  A+ R + ++L+ +   L +  + EL+ G+    FR++  D         ++ Y  
Sbjct: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYD 137

Query: 134 NDERSRAVDHVQRSLSCCGVQNYTNWSTSPYF-------LEHGIPPSCCMNETD------ 180
           + +    +D VQ+   CCG ++Y +WS + Y        L  G+P +CC+  T       
Sbjct: 138 DLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTM 197

Query: 181 CNPQDLHNLTVAATKV-NQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLL 233
           C  + +     +   V   +GC + V  +   N  I+AG+  GI   Q +G+LL
Sbjct: 198 CGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLL 251


>gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]
          Length = 270

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 64/248 (25%), Positives = 111/248 (44%), Gaps = 20/248 (8%)

Query: 16  KTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNA--PYVLI-GTGTTIVVF 72
           K LL  Y+ +FW+ GV+ L VG+W     G    L      +   P VL+   G  +   
Sbjct: 16  KYLLFSYNIIFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVLVLMVGVVMFTL 75

Query: 73  GLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTYN 132
           G  GC    R +  +L  +   + L+F  EL   +  F+F+  ++D F   +   +++Y 
Sbjct: 76  GFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIKSYR 135

Query: 133 GNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYF---------LEHGIPPSCCMNETD--- 180
            + +    +D +Q++  CCG     +W  + YF          + G+P SCC+ +     
Sbjct: 136 DDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKV 195

Query: 181 CNPQDLHNLTVAA-----TKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLAC 235
            N Q  +++ +         +  KGC   + S++  N+ I+AGV   I+  Q+ G+ LA 
Sbjct: 196 VNTQCGYDVRIQLKSKWDESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFGIFLAR 255

Query: 236 CLSRFITA 243
            L   I A
Sbjct: 256 TLISDIEA 263


>gi|38787991 transmembrane 4 superfamily member 8 isoform 2 [Homo
           sapiens]
          Length = 228

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 72/231 (31%), Positives = 103/231 (44%), Gaps = 37/231 (16%)

Query: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAP-YVLIGTGTTIV 70
           IT  KT+L+  + +FW    IL  VG +  +T   Y     +  T  P  V+I  G  + 
Sbjct: 6   ITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLF 65

Query: 71  VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130
           + GL GC AT R S   L                         +E+  +  + Y    +T
Sbjct: 66  IIGLIGCCATIRESRCGLA---------------------TVENEVDRSIQKVY----KT 100

Query: 131 YNGN--DERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLE---HGIPPSCCM-NETDCNPQ 184
           YNG   D  SRA+D+VQR L CCG+ NY++W  + +F E     +P SCC    ++CN  
Sbjct: 101 YNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGS 160

Query: 185 DLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLAC 235
             H   + A     +GC  LV   ++  M  +   A   A  QL+GML AC
Sbjct: 161 LAHPSDLYA-----EGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 206


>gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]
          Length = 267

 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 57/228 (25%), Positives = 109/228 (47%), Gaps = 20/228 (8%)

Query: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENST--NAPYVLIGTGTTI 69
           ++C+K L+ +++F  ++ G  LLA+G+W  +    +  ++A N       Y+L+  G  +
Sbjct: 6   LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLL 65

Query: 70  VVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEI-KDTFLRTYTDAM 128
            + G  GC    R +  +L  + +F+ ++FLAEL A I  F+FR  + ++ F +  T   
Sbjct: 66  FLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHY 125

Query: 129 QTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFL-----EHGIPPSCCMNETDCNP 183
           Q  N  D  S   + V  +  CCGV    ++  +  F         +P +CC  E    P
Sbjct: 126 QGNNDTDVFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRRE----P 181

Query: 184 QDLHNLTVAATK--------VNQKGCYDLVTSFMETNMGIIAGVAFGI 223
           Q    + ++  +        +N++GCY ++ +  ET + +   +A G+
Sbjct: 182 QSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGV 229


>gi|67782354 CD82 antigen isoform 2 [Homo sapiens]
          Length = 242

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 69/259 (26%), Positives = 117/259 (45%), Gaps = 46/259 (17%)

Query: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTN---APYVLIGTGTT 68
           I   K  L +++ +F+I G ++L  GVW      ++IS++  +S++     YV IG G  
Sbjct: 6   IKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAV 65

Query: 69  IVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAM 128
            ++ G  GC         +L L         L + + GI                 T+ +
Sbjct: 66  TMLMGFLGCIGAVNEVRCLLGL---------LKQEMGGI----------------VTELI 100

Query: 129 QTYNGNDERSR--AVDHVQRSLSCCGVQNYTNWSTSPYFL---EHGIPPSCCMNETDCNP 183
           + YN + E S   A D+VQ  + CCG  ++ NW+ +   +   E   P SC +   + N 
Sbjct: 101 RDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNS 160

Query: 184 QDLH--------NLTVAATK-----VNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIG 230
             +         N T +        V Q+GC + V ++++ N+GII GV  G+A  +L+G
Sbjct: 161 LSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLG 220

Query: 231 MLLACCLSRFITANQYEMV 249
           M+L+ CL R + +  Y  V
Sbjct: 221 MVLSICLCRHVHSEDYSKV 239


>gi|4502693 CD9 antigen [Homo sapiens]
          Length = 228

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 71/253 (28%), Positives = 106/253 (41%), Gaps = 34/253 (13%)

Query: 6   METKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTN-------- 57
           M  K    C+K LL  ++F+FW+ G+ +LA+G+W  L   +    I E  TN        
Sbjct: 1   MPVKGGTKCIKYLLFGFNFIFWLAGIAVLAIGLW--LRFDSQTKSIFEQETNNNNSSFYT 58

Query: 58  APYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIK 117
             Y+LIG G  +++ G  GC    + S  ML L+  FL ++F  E+ A I G+  + E+ 
Sbjct: 59  GVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVI 118

Query: 118 DTFLRTYTDAMQTYNGNDERSR-AVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCM 176
                 Y D        DE  R  +  +  +L+CCG+            +E  I   C  
Sbjct: 119 KEVQEFYKDTYNKLKTKDEPQRETLKAIHYALNCCGLAG---------GVEQFISDICPK 169

Query: 177 NETDCNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACC 236
            +       L   TV       K C D +    +    II  V  GIA   + GM+ +  
Sbjct: 170 KDV------LETFTV-------KSCPDAIKEVFDNKFHIIGAVGIGIAVVMIFGMIFSMI 216

Query: 237 LSRFITANQYEMV 249
           L   I  N+ EMV
Sbjct: 217 LCCAIRRNR-EMV 228


>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
          Length = 237

 Score = 91.3 bits (225), Expect = 7e-19
 Identities = 56/236 (23%), Positives = 113/236 (47%), Gaps = 18/236 (7%)

Query: 11  VITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYV----LIGTG 66
           V  C+K  +  ++F+FW+ G+++LA+ +W +++  +     +E+  ++ YV    LI  G
Sbjct: 4   VSACIKYSMFTFNFLFWLCGILILALAIWVRVSNDSQAIFGSEDVGSSSYVAVDILIAVG 63

Query: 67  TTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHE----IKDTFLR 122
             I++ G  GC    + S  ML L+ + L L+ L ++  GI G VF+ +    + +T   
Sbjct: 64  AIIMILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETLYE 123

Query: 123 TYTDAMQTYNGNDERSRAVDHVQRSLSCCGVQN-YTNWSTSPYFLEHGIPPSCCMNETDC 181
                  T     +   A+   Q    CCG+ N   +W  +    +H      C+++   
Sbjct: 124 NTKLLSATGESEKQFQEAIIVFQEEFKCCGLVNGAADWGNN---FQHYPELCACLDKQ-- 178

Query: 182 NPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCL 237
            P   +N      +V ++ C   +  F+  N+ I+ G++FG+A  +++G++ +  L
Sbjct: 179 RPCQSYN----GKQVYKETCISFIKDFLAKNLIIVIGISFGLAVIEILGLVFSMVL 230


>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 60/227 (26%), Positives = 104/227 (45%), Gaps = 13/227 (5%)

Query: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAE-NSTNAPYVLIGTGTTIV 70
           +  +K L+  ++ +FW+ G  +L VG+W   T G++ +L +   S +A  +LI TG  ++
Sbjct: 6   LQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVM 65

Query: 71  VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130
             G  GC    + +  +L  + + L LVFL E    I  F +  +I     +     +  
Sbjct: 66  AIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHL 125

Query: 131 Y--NGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETD-CNPQDLH 187
           Y   GN   + A   +Q    CCGV NYT+W     +    +P SCC+  ++ C    LH
Sbjct: 126 YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDW--FEVYNATRVPDSCCLEFSESCG---LH 180

Query: 188 NLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLA 234
               A     +  CY+ V  +++ N+  +       A  Q++G+  A
Sbjct: 181 ----APGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFA 223


>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 60/227 (26%), Positives = 104/227 (45%), Gaps = 13/227 (5%)

Query: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAE-NSTNAPYVLIGTGTTIV 70
           +  +K L+  ++ +FW+ G  +L VG+W   T G++ +L +   S +A  +LI TG  ++
Sbjct: 6   LQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVM 65

Query: 71  VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130
             G  GC    + +  +L  + + L LVFL E    I  F +  +I     +     +  
Sbjct: 66  AIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHL 125

Query: 131 Y--NGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETD-CNPQDLH 187
           Y   GN   + A   +Q    CCGV NYT+W     +    +P SCC+  ++ C    LH
Sbjct: 126 YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDW--FEVYNATRVPDSCCLEFSESCG---LH 180

Query: 188 NLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLA 234
               A     +  CY+ V  +++ N+  +       A  Q++G+  A
Sbjct: 181 ----APGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFA 223


>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 60/227 (26%), Positives = 104/227 (45%), Gaps = 13/227 (5%)

Query: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAE-NSTNAPYVLIGTGTTIV 70
           +  +K L+  ++ +FW+ G  +L VG+W   T G++ +L +   S +A  +LI TG  ++
Sbjct: 6   LQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVM 65

Query: 71  VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130
             G  GC    + +  +L  + + L LVFL E    I  F +  +I     +     +  
Sbjct: 66  AIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHL 125

Query: 131 Y--NGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETD-CNPQDLH 187
           Y   GN   + A   +Q    CCGV NYT+W     +    +P SCC+  ++ C    LH
Sbjct: 126 YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDW--FEVYNATRVPDSCCLEFSESCG---LH 180

Query: 188 NLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLA 234
               A     +  CY+ V  +++ N+  +       A  Q++G+  A
Sbjct: 181 ----APGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFA 223


>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 60/227 (26%), Positives = 104/227 (45%), Gaps = 13/227 (5%)

Query: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAE-NSTNAPYVLIGTGTTIV 70
           +  +K L+  ++ +FW+ G  +L VG+W   T G++ +L +   S +A  +LI TG  ++
Sbjct: 6   LQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVM 65

Query: 71  VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130
             G  GC    + +  +L  + + L LVFL E    I  F +  +I     +     +  
Sbjct: 66  AIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHL 125

Query: 131 Y--NGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETD-CNPQDLH 187
           Y   GN   + A   +Q    CCGV NYT+W     +    +P SCC+  ++ C    LH
Sbjct: 126 YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDW--FEVYNATRVPDSCCLEFSESCG---LH 180

Query: 188 NLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLA 234
               A     +  CY+ V  +++ N+  +       A  Q++G+  A
Sbjct: 181 ----APGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFA 223


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.139    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,266,528
Number of Sequences: 37866
Number of extensions: 318794
Number of successful extensions: 1025
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 890
Number of HSP's gapped (non-prelim): 53
length of query: 249
length of database: 18,247,518
effective HSP length: 100
effective length of query: 149
effective length of database: 14,460,918
effective search space: 2154676782
effective search space used: 2154676782
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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