Guide to the Human Genome
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Search of human proteins with 21264580

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21264580 tetraspan 2 [Homo sapiens]
         (221 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21264580 tetraspan 2 [Homo sapiens]                                451   e-127
gi|4502693 CD9 antigen [Homo sapiens]                                 209   1e-54
gi|4757944 CD81 antigen [Homo sapiens]                                180   1e-45
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]        115   2e-26
gi|87159824 CD151 antigen [Homo sapiens]                              107   1e-23
gi|87159822 CD151 antigen [Homo sapiens]                              107   1e-23
gi|21237751 CD151 antigen [Homo sapiens]                              107   1e-23
gi|21237748 CD151 antigen [Homo sapiens]                              107   1e-23
gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]                    96   2e-20
gi|68800005 tetraspanin 4 isoform a [Homo sapiens]                     96   3e-20
gi|4507543 tetraspanin 4 isoform a [Homo sapiens]                      96   3e-20
gi|68800018 tetraspanin 4 isoform a [Homo sapiens]                     96   3e-20
gi|68800024 tetraspanin 4 isoform a [Homo sapiens]                     96   3e-20
gi|68800011 tetraspanin 4 isoform a [Homo sapiens]                     96   3e-20
gi|68799997 tetraspanin 4 isoform a [Homo sapiens]                     96   3e-20
gi|4504813 CD82 antigen isoform 1 [Homo sapiens]                       94   9e-20
gi|10834972 CD53 antigen [Homo sapiens]                                94   9e-20
gi|91106727 CD53 antigen [Homo sapiens]                                94   9e-20
gi|122937466 tetraspanin 11 [Homo sapiens]                             92   3e-19
gi|21264578 tetraspan 1 [Homo sapiens]                                 92   5e-19
gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]                    89   2e-18
gi|5729941 tetraspanin 9 [Homo sapiens]                                86   3e-17
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]        82   4e-16
gi|50511934 transmembrane 4 superfamily member 17 isoform b [Hom...    79   3e-15
gi|54859560 transmembrane 4 superfamily member 17 isoform a [Hom...    78   7e-15
gi|54859505 transmembrane 4 superfamily member 17 isoform c [Hom...    77   1e-14
gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]                   75   3e-14
gi|30425534 tetraspanin 33 [Homo sapiens]                              73   2e-13
gi|21265104 tetraspanin 7 [Homo sapiens]                               72   4e-13
gi|4502679 CD63 antigen isoform A [Homo sapiens]                       72   4e-13

>gi|21264580 tetraspan 2 [Homo sapiens]
          Length = 221

 Score =  451 bits (1161), Expect = e-127
 Identities = 221/221 (100%), Positives = 221/221 (100%)

Query: 1   MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLY 60
           MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLY
Sbjct: 1   MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLY 60

Query: 61  VLVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHV 120
           VLVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHV
Sbjct: 61  VLVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHV 120

Query: 121 QTMYEEAYNDYLKDRGKGNGTLITFHSTFQCCGKESSEQVQPTCPKELLGHKNCIDEIET 180
           QTMYEEAYNDYLKDRGKGNGTLITFHSTFQCCGKESSEQVQPTCPKELLGHKNCIDEIET
Sbjct: 121 QTMYEEAYNDYLKDRGKGNGTLITFHSTFQCCGKESSEQVQPTCPKELLGHKNCIDEIET 180

Query: 181 IISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI 221
           IISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI
Sbjct: 181 IISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI 221


>gi|4502693 CD9 antigen [Homo sapiens]
          Length = 228

 Score =  209 bits (533), Expect = 1e-54
 Identities = 105/225 (46%), Positives = 138/225 (61%), Gaps = 8/225 (3%)

Query: 5   RGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSED--KSPEYFYVGLYVL 62
           +GG +CIKYLL GFN +FWLAG AV+A GLW RF    K +  ++   +   FY G+Y+L
Sbjct: 4   KGGTKCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTGVYIL 63

Query: 63  VGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQT 122
           +GAGALMM VGF GCCGA++ESQC+LG FF  LLVIFA E+   ++ +  K   I+ VQ 
Sbjct: 64  IGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQE 123

Query: 123 MYEEAYNDYLKDRGKGNGTLITFHSTFQCCGKESSEQ--VQPTCPK----ELLGHKNCID 176
            Y++ YN           TL   H    CCG     +  +   CPK    E    K+C D
Sbjct: 124 FYKDTYNKLKTKDEPQRETLKAIHYALNCCGLAGGVEQFISDICPKKDVLETFTVKSCPD 183

Query: 177 EIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI 221
            I+ +   K  +IG VGIGIA + IFGMIFSM+LCCAIR +R+++
Sbjct: 184 AIKEVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRNREMV 228


>gi|4757944 CD81 antigen [Homo sapiens]
          Length = 236

 Score =  180 bits (456), Expect = 1e-45
 Identities = 94/229 (41%), Positives = 130/229 (56%), Gaps = 17/229 (7%)

Query: 6   GGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELS----SEDKSPEYFYVGLYV 61
           G  +CIKYLL  FN +FWLAG  ++   LW R       L      +  +P  FYVG+Y+
Sbjct: 5   GCTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYI 64

Query: 62  LVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQ 121
           L+  GA+MM VGF GC GA++ESQC+LG+FFTCL+++FA EV  G++ F+ K    + V+
Sbjct: 65  LIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVK 124

Query: 122 TMYEEAYNDYLKDRGKGNGTLI--TFHSTFQCCGKESSEQVQPT------CPK-----EL 168
             Y++A    + D    N   +  TFH T  CCG  +   +  +      CP        
Sbjct: 125 QFYDQALQQAVVDDDANNAKAVVKTFHETLDCCGSSTLTALTTSVLKNNLCPSGSNIISN 184

Query: 169 LGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNS 217
           L  ++C  +I+ + S KL LIGI  I +A + IF MI SMVLCC IRNS
Sbjct: 185 LFKEDCHQKIDDLFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNS 233


>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
          Length = 237

 Score =  115 bits (289), Expect = 2e-26
 Identities = 71/232 (30%), Positives = 112/232 (48%), Gaps = 27/232 (11%)

Query: 10  CIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAGALM 69
           CIKY +  FN LFWL G  ++A  +W R     + +   +      YV + +L+  GA++
Sbjct: 7   CIKYSMFTFNFLFWLCGILILALAIWVRVSNDSQAIFGSEDVGSSSYVAVDILIAVGAII 66

Query: 70  MAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHV-QTMYEEAY 128
           M +GF GCCGA++ES+C+L  FF  LL+I   +V TG+   + K  + R V +T+YE   
Sbjct: 67  MILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETLYENT- 125

Query: 129 NDYLKDRGKGNG----TLITFHSTFQCCGKESSE-----------------QVQPTCPK- 166
              L   G+        +I F   F+CCG  +                     Q  C   
Sbjct: 126 -KLLSATGESEKQFQEAIIVFQEEFKCCGLVNGAADWGNNFQHYPELCACLDKQRPCQSY 184

Query: 167 --ELLGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRN 216
             + +  + CI  I+  ++  L ++  +  G+A + I G++FSMVL C I N
Sbjct: 185 NGKQVYKETCISFIKDFLAKNLIIVIGISFGLAVIEILGLVFSMVLYCQIGN 236


>gi|87159824 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  107 bits (266), Expect = 1e-23
 Identities = 76/246 (30%), Positives = 112/246 (45%), Gaps = 46/246 (18%)

Query: 7   GLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAG 66
           G  C+KYLL  +N  FWLAG AV+A G+W     A+K       +   +    Y+LV AG
Sbjct: 12  GTVCLKYLLFTYNCCFWLAGLAVMAVGIWTL---ALKSDYISLLASGTYLATAYILVVAG 68

Query: 67  ALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEE 126
            ++M  G  GCC   +E + +L  +F  LL+IF  E+  G+ A+       + + T  +E
Sbjct: 69  TVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAY----AYYQQLNTELKE 124

Query: 127 AYNDYLKDRGKGNG------TLITFHSTFQCCGKESSEQ----------------VQPTC 164
              D +  R    G       +      F CCG  +S+                 V  +C
Sbjct: 125 NLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSC 184

Query: 165 PK---ELLGHKN-----------CIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVL 210
            K    L G ++           CI ++ET I   L++IG VGIGIA + +FGMIF+   
Sbjct: 185 CKTVVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFT--- 241

Query: 211 CCAIRN 216
           CC  R+
Sbjct: 242 CCLYRS 247


>gi|87159822 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  107 bits (266), Expect = 1e-23
 Identities = 76/246 (30%), Positives = 112/246 (45%), Gaps = 46/246 (18%)

Query: 7   GLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAG 66
           G  C+KYLL  +N  FWLAG AV+A G+W     A+K       +   +    Y+LV AG
Sbjct: 12  GTVCLKYLLFTYNCCFWLAGLAVMAVGIWTL---ALKSDYISLLASGTYLATAYILVVAG 68

Query: 67  ALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEE 126
            ++M  G  GCC   +E + +L  +F  LL+IF  E+  G+ A+       + + T  +E
Sbjct: 69  TVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAY----AYYQQLNTELKE 124

Query: 127 AYNDYLKDRGKGNG------TLITFHSTFQCCGKESSEQ----------------VQPTC 164
              D +  R    G       +      F CCG  +S+                 V  +C
Sbjct: 125 NLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSC 184

Query: 165 PK---ELLGHKN-----------CIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVL 210
            K    L G ++           CI ++ET I   L++IG VGIGIA + +FGMIF+   
Sbjct: 185 CKTVVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFT--- 241

Query: 211 CCAIRN 216
           CC  R+
Sbjct: 242 CCLYRS 247


>gi|21237751 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  107 bits (266), Expect = 1e-23
 Identities = 76/246 (30%), Positives = 112/246 (45%), Gaps = 46/246 (18%)

Query: 7   GLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAG 66
           G  C+KYLL  +N  FWLAG AV+A G+W     A+K       +   +    Y+LV AG
Sbjct: 12  GTVCLKYLLFTYNCCFWLAGLAVMAVGIWTL---ALKSDYISLLASGTYLATAYILVVAG 68

Query: 67  ALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEE 126
            ++M  G  GCC   +E + +L  +F  LL+IF  E+  G+ A+       + + T  +E
Sbjct: 69  TVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAY----AYYQQLNTELKE 124

Query: 127 AYNDYLKDRGKGNG------TLITFHSTFQCCGKESSEQ----------------VQPTC 164
              D +  R    G       +      F CCG  +S+                 V  +C
Sbjct: 125 NLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSC 184

Query: 165 PK---ELLGHKN-----------CIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVL 210
            K    L G ++           CI ++ET I   L++IG VGIGIA + +FGMIF+   
Sbjct: 185 CKTVVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFT--- 241

Query: 211 CCAIRN 216
           CC  R+
Sbjct: 242 CCLYRS 247


>gi|21237748 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  107 bits (266), Expect = 1e-23
 Identities = 76/246 (30%), Positives = 112/246 (45%), Gaps = 46/246 (18%)

Query: 7   GLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAG 66
           G  C+KYLL  +N  FWLAG AV+A G+W     A+K       +   +    Y+LV AG
Sbjct: 12  GTVCLKYLLFTYNCCFWLAGLAVMAVGIWTL---ALKSDYISLLASGTYLATAYILVVAG 68

Query: 67  ALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEE 126
            ++M  G  GCC   +E + +L  +F  LL+IF  E+  G+ A+       + + T  +E
Sbjct: 69  TVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAY----AYYQQLNTELKE 124

Query: 127 AYNDYLKDRGKGNG------TLITFHSTFQCCGKESSEQ----------------VQPTC 164
              D +  R    G       +      F CCG  +S+                 V  +C
Sbjct: 125 NLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSC 184

Query: 165 PK---ELLGHKN-----------CIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVL 210
            K    L G ++           CI ++ET I   L++IG VGIGIA + +FGMIF+   
Sbjct: 185 CKTVVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFT--- 241

Query: 211 CCAIRN 216
           CC  R+
Sbjct: 242 CCLYRS 247


>gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]
          Length = 248

 Score = 96.3 bits (238), Expect = 2e-20
 Identities = 66/248 (26%), Positives = 105/248 (42%), Gaps = 55/248 (22%)

Query: 8   LRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGA-IKELSSEDKSPEYFYVGLYVLVGAG 66
           L C+KYL+  FN   +L G+ ++A G+W        +E+ + +        G Y+L+  G
Sbjct: 6   LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANP---LLLTGAYILLAMG 62

Query: 67  ALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEE 126
            L+  +GF GCCGA+RE++C+L  FF  +L+IF AE++  + AFI +       + +  E
Sbjct: 63  GLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFR-------ENLTRE 115

Query: 127 AYNDYLKDRGKGNGTLITFHS-------TFQCCGKE----------------SSEQVQPT 163
            +   L    +GN     F +       TF CCG                   SE+V   
Sbjct: 116 FFTKELTKHYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEA 175

Query: 164 CPKE---------------------LLGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIF 202
           C +                       L  + C   I       + L G + IG+  + +F
Sbjct: 176 CCRREPQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELF 235

Query: 203 GMIFSMVL 210
            MIF+M L
Sbjct: 236 AMIFAMCL 243


>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 95.5 bits (236), Expect = 3e-20
 Identities = 65/232 (28%), Positives = 105/232 (45%), Gaps = 26/232 (11%)

Query: 5   RGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFG-GAIKELSSEDKSPEYFYVGLYVLV 63
           R  L+ +KYL+  FNLLFWL G  V+  G+W     G+   LSS   S         +L+
Sbjct: 3   RACLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLS----AANLLI 58

Query: 64  GAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTM 123
             GA +MA+GF GC GA++E++C+L +FF  LL++F  E T  +  F       R+ Q  
Sbjct: 59  ITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQD 118

Query: 124 YEEAYNDYLKDRGKG-NGTLITFHSTFQCCGKE---------SSEQVQPTCPKEL----- 168
            ++  + Y      G         + F+CCG           ++ +V  +C  E      
Sbjct: 119 LKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCG 178

Query: 169 ------LGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAI 214
                      C + ++  +   L  +GI G+  A + I G+ F+M + C +
Sbjct: 179 LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQV 230


>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 95.5 bits (236), Expect = 3e-20
 Identities = 65/232 (28%), Positives = 105/232 (45%), Gaps = 26/232 (11%)

Query: 5   RGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFG-GAIKELSSEDKSPEYFYVGLYVLV 63
           R  L+ +KYL+  FNLLFWL G  V+  G+W     G+   LSS   S         +L+
Sbjct: 3   RACLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLS----AANLLI 58

Query: 64  GAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTM 123
             GA +MA+GF GC GA++E++C+L +FF  LL++F  E T  +  F       R+ Q  
Sbjct: 59  ITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQD 118

Query: 124 YEEAYNDYLKDRGKG-NGTLITFHSTFQCCGKE---------SSEQVQPTCPKEL----- 168
            ++  + Y      G         + F+CCG           ++ +V  +C  E      
Sbjct: 119 LKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCG 178

Query: 169 ------LGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAI 214
                      C + ++  +   L  +GI G+  A + I G+ F+M + C +
Sbjct: 179 LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQV 230


>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 95.5 bits (236), Expect = 3e-20
 Identities = 65/232 (28%), Positives = 105/232 (45%), Gaps = 26/232 (11%)

Query: 5   RGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFG-GAIKELSSEDKSPEYFYVGLYVLV 63
           R  L+ +KYL+  FNLLFWL G  V+  G+W     G+   LSS   S         +L+
Sbjct: 3   RACLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLS----AANLLI 58

Query: 64  GAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTM 123
             GA +MA+GF GC GA++E++C+L +FF  LL++F  E T  +  F       R+ Q  
Sbjct: 59  ITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQD 118

Query: 124 YEEAYNDYLKDRGKG-NGTLITFHSTFQCCGKE---------SSEQVQPTCPKEL----- 168
            ++  + Y      G         + F+CCG           ++ +V  +C  E      
Sbjct: 119 LKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCG 178

Query: 169 ------LGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAI 214
                      C + ++  +   L  +GI G+  A + I G+ F+M + C +
Sbjct: 179 LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQV 230


>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 95.5 bits (236), Expect = 3e-20
 Identities = 65/232 (28%), Positives = 105/232 (45%), Gaps = 26/232 (11%)

Query: 5   RGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFG-GAIKELSSEDKSPEYFYVGLYVLV 63
           R  L+ +KYL+  FNLLFWL G  V+  G+W     G+   LSS   S         +L+
Sbjct: 3   RACLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLS----AANLLI 58

Query: 64  GAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTM 123
             GA +MA+GF GC GA++E++C+L +FF  LL++F  E T  +  F       R+ Q  
Sbjct: 59  ITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQD 118

Query: 124 YEEAYNDYLKDRGKG-NGTLITFHSTFQCCGKE---------SSEQVQPTCPKEL----- 168
            ++  + Y      G         + F+CCG           ++ +V  +C  E      
Sbjct: 119 LKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCG 178

Query: 169 ------LGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAI 214
                      C + ++  +   L  +GI G+  A + I G+ F+M + C +
Sbjct: 179 LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQV 230


>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 95.5 bits (236), Expect = 3e-20
 Identities = 65/232 (28%), Positives = 105/232 (45%), Gaps = 26/232 (11%)

Query: 5   RGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFG-GAIKELSSEDKSPEYFYVGLYVLV 63
           R  L+ +KYL+  FNLLFWL G  V+  G+W     G+   LSS   S         +L+
Sbjct: 3   RACLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLS----AANLLI 58

Query: 64  GAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTM 123
             GA +MA+GF GC GA++E++C+L +FF  LL++F  E T  +  F       R+ Q  
Sbjct: 59  ITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQD 118

Query: 124 YEEAYNDYLKDRGKG-NGTLITFHSTFQCCGKE---------SSEQVQPTCPKEL----- 168
            ++  + Y      G         + F+CCG           ++ +V  +C  E      
Sbjct: 119 LKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCG 178

Query: 169 ------LGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAI 214
                      C + ++  +   L  +GI G+  A + I G+ F+M + C +
Sbjct: 179 LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQV 230


>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 95.5 bits (236), Expect = 3e-20
 Identities = 65/232 (28%), Positives = 105/232 (45%), Gaps = 26/232 (11%)

Query: 5   RGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFG-GAIKELSSEDKSPEYFYVGLYVLV 63
           R  L+ +KYL+  FNLLFWL G  V+  G+W     G+   LSS   S         +L+
Sbjct: 3   RACLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLS----AANLLI 58

Query: 64  GAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTM 123
             GA +MA+GF GC GA++E++C+L +FF  LL++F  E T  +  F       R+ Q  
Sbjct: 59  ITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQD 118

Query: 124 YEEAYNDYLKDRGKG-NGTLITFHSTFQCCGKE---------SSEQVQPTCPKEL----- 168
            ++  + Y      G         + F+CCG           ++ +V  +C  E      
Sbjct: 119 LKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCG 178

Query: 169 ------LGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAI 214
                      C + ++  +   L  +GI G+  A + I G+ F+M + C +
Sbjct: 179 LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQV 230


>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
          Length = 267

 Score = 94.0 bits (232), Expect = 9e-20
 Identities = 63/249 (25%), Positives = 107/249 (42%), Gaps = 46/249 (18%)

Query: 8   LRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAGA 67
           ++  KY L  FNL+F++ G+ ++ FG+W         +S    S     +G YV +G GA
Sbjct: 6   IKVTKYFLFLFNLIFFILGAVILGFGVWI-LADKSSFISVLQTSSSSLRMGAYVFIGVGA 64

Query: 68  LMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEA 127
           + M +GF GC GA+ E +C+LG +F  LL+I  A+VT G   +   G   + +  +  E 
Sbjct: 65  VTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTEL 124

Query: 128 YNDYLKDRGKGNGTLITF-HSTFQCCGKES------------SEQVQPTCPKELLGHKN- 173
             DY   R         +  +  +CCG  S              +V   C  E+ G ++ 
Sbjct: 125 IRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDN 184

Query: 174 -------------------------------CIDEIETIISVKLQLIGIVGIGIAGLTIF 202
                                          C+++++  +   L +I  VG+G+A + + 
Sbjct: 185 SLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELL 244

Query: 203 GMIFSMVLC 211
           GM+ S+ LC
Sbjct: 245 GMVLSICLC 253


>gi|10834972 CD53 antigen [Homo sapiens]
          Length = 219

 Score = 94.0 bits (232), Expect = 9e-20
 Identities = 62/222 (27%), Positives = 104/222 (46%), Gaps = 18/222 (8%)

Query: 8   LRCIKYLLLGFNLLFWLAGSAVIAFGLWF----RFGGAIKELSSEDKSPEYFYVGLYVLV 63
           L+ +KY+L  FNLLFW+ G  ++ FG++      FG     L      P      ++V+V
Sbjct: 6   LKLLKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNL------PSLTLGNVFVIV 59

Query: 64  GAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTM 123
           G+  ++M V F GC G+++E++C+L SFF  LL+I  AEVT  +  F+ +     +V   
Sbjct: 60  GS--IIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKG 117

Query: 124 YEEAYNDYLKDRGKGNGTLITFHSTFQCCG----KESSEQVQPTCPKELLGHKNCIDEIE 179
             ++ + Y  D         +  S  QCCG     + +     +CP +    + C  +  
Sbjct: 118 LTDSIHRYHSDNST-KAAWDSIQSFLQCCGINGTSDWTSGPPASCPSD-RKVEGCYAKAR 175

Query: 180 TIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI 221
                    IGI+ I +  + + GM F++ L C I  +   I
Sbjct: 176 LWFHSNFLYIGIITICVCVIEVLGMSFALTLNCQIDKTSQTI 217


>gi|91106727 CD53 antigen [Homo sapiens]
          Length = 219

 Score = 94.0 bits (232), Expect = 9e-20
 Identities = 62/222 (27%), Positives = 104/222 (46%), Gaps = 18/222 (8%)

Query: 8   LRCIKYLLLGFNLLFWLAGSAVIAFGLWF----RFGGAIKELSSEDKSPEYFYVGLYVLV 63
           L+ +KY+L  FNLLFW+ G  ++ FG++      FG     L      P      ++V+V
Sbjct: 6   LKLLKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNL------PSLTLGNVFVIV 59

Query: 64  GAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTM 123
           G+  ++M V F GC G+++E++C+L SFF  LL+I  AEVT  +  F+ +     +V   
Sbjct: 60  GS--IIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKG 117

Query: 124 YEEAYNDYLKDRGKGNGTLITFHSTFQCCG----KESSEQVQPTCPKELLGHKNCIDEIE 179
             ++ + Y  D         +  S  QCCG     + +     +CP +    + C  +  
Sbjct: 118 LTDSIHRYHSDNST-KAAWDSIQSFLQCCGINGTSDWTSGPPASCPSD-RKVEGCYAKAR 175

Query: 180 TIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI 221
                    IGI+ I +  + + GM F++ L C I  +   I
Sbjct: 176 LWFHSNFLYIGIITICVCVIEVLGMSFALTLNCQIDKTSQTI 217


>gi|122937466 tetraspanin 11 [Homo sapiens]
          Length = 253

 Score = 92.0 bits (227), Expect = 3e-19
 Identities = 74/248 (29%), Positives = 107/248 (43%), Gaps = 66/248 (26%)

Query: 11  IKYLLLGFNLLFWLAGSAVIAFGLW--FRFGGAIKELSSEDKSPEYFYVGLYVLVGAGAL 68
           +KYLL  FN  FW+ G+AV+A G+W      G +  L+S       F    Y+L+ AG L
Sbjct: 16  LKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASST-----FAASAYILIFAGVL 70

Query: 69  MMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAY 128
           +M  GF G    + E +  L ++F  LLVIF  E+  GV A +            Y +  
Sbjct: 71  VMVTGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHV------------YYQRL 118

Query: 129 NDYLKDR---------GKGNGTLIT-----FHSTFQCCGKESS----------------E 158
           +D LK           G+   T IT         F+CCG  SS                 
Sbjct: 119 SDELKQHLNRTLAENYGQPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGR 178

Query: 159 QVQPTCPKELL------GHKN--------CIDEIETIISVKLQLIGIVGIGIAGLTIFGM 204
           QV  +C K ++       H +        C+ ++E  ++  L L+G VGIG+A L I GM
Sbjct: 179 QVPDSCCKTVVVRCGQRAHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQICGM 238

Query: 205 IFSMVLCC 212
           + +   CC
Sbjct: 239 VLT---CC 243


>gi|21264578 tetraspan 1 [Homo sapiens]
          Length = 241

 Score = 91.7 bits (226), Expect = 5e-19
 Identities = 72/238 (30%), Positives = 106/238 (44%), Gaps = 36/238 (15%)

Query: 11  IKYLLLGFNLLFWLAGSAVIAFGLWFRFGGA--IKELSSEDKSPEYFYVGLYVLVGAGAL 68
           IK +++ FNLL +L G+A++A G+W    GA  +K       S   F    Y L+ AG +
Sbjct: 7   IKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVV 66

Query: 69  MMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAY 128
           + A+GF GC GA  ES+C L +FF  LL+IF AEV   V A +   +A   +  +   A 
Sbjct: 67  VFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAI 126

Query: 129 NDYLKDRGKGNGTLITFHST---FQCCG-------------KESS------------EQV 160
               KD G        +++T    +CCG             KE+S               
Sbjct: 127 K---KDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVTNTA 183

Query: 161 QPTCPKELLGH---KNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIR 215
             TC K+       + C +++   I      +G V  GI GL +  MI SM L C ++
Sbjct: 184 NETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNLQ 241


>gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]
          Length = 267

 Score = 89.4 bits (220), Expect = 2e-18
 Identities = 50/159 (31%), Positives = 80/159 (50%), Gaps = 18/159 (11%)

Query: 8   LRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGA-IKELSSEDKSPEYFYVGLYVLVGAG 66
           L C+KYL+  FN   +L G+ ++A G+W        +E+ + +        G Y+L+  G
Sbjct: 6   LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANP---LLLTGAYILLAMG 62

Query: 67  ALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEE 126
            L+  +GF GCCGA+RE++C+L  FF  +L+IF AE++  + AFI +       + +  E
Sbjct: 63  GLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFR-------ENLTRE 115

Query: 127 AYNDYLKDRGKGNGTLITFHS-------TFQCCGKESSE 158
            +   L    +GN     F +       TF CCG    E
Sbjct: 116 FFTKELTKHYQGNNDTDVFSATWNSVMITFGCCGVNGPE 154


>gi|5729941 tetraspanin 9 [Homo sapiens]
          Length = 239

 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 63/228 (27%), Positives = 100/228 (43%), Gaps = 26/228 (11%)

Query: 5   RGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVG 64
           RG L C+KY++  FNL+FWL G  ++  G+W     ++ + +    SP +  +    LV 
Sbjct: 3   RGCLCCLKYMMFLFNLIFWLCGCGLLGVGIWL----SVSQGNFATFSPSFPSLSAANLVI 58

Query: 65  A-GALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTM 123
           A G ++M  GF GC GA++E++C+L SFF  LLVI  AE+   +  F+       + +  
Sbjct: 59  AIGTIVMVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKD 118

Query: 124 YEEAYNDYLKDRGKG-NGTLITFHSTFQCCGKESSEQVQP-----TCPKEL--------- 168
            +E    Y  +   G         +  +CCG        P     T P            
Sbjct: 119 LKEGLLLYHTENNVGLKNAWNIIQAEMRCCGVTDYTDWYPVLGENTVPDRCCMENSQGCG 178

Query: 169 ------LGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVL 210
                 L    C ++++        ++G VG+ I  + I GM FSM L
Sbjct: 179 RNATTPLWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFSMTL 226


>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
          Length = 268

 Score = 82.0 bits (201), Expect = 4e-16
 Identities = 69/254 (27%), Positives = 106/254 (41%), Gaps = 47/254 (18%)

Query: 10  CIKYLLLGFNLLFWLAGSAVIAFGLW-FRFGGAIKELSSEDKSPEYFYVGLYVLVGAGAL 68
           CIKY + GFN++FW  G   +  GLW +   G +  +SS      +  V L+++VG   +
Sbjct: 14  CIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGG--V 71

Query: 69  MMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAY 128
           M  +GF GC GA+RE+  +L  F   L +IF  E+T GV AF+ K      +        
Sbjct: 72  MFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFINNNI 131

Query: 129 NDYLKDRGKGN--------------------GTLITFHST------------FQCCGKES 156
             Y  D    N                       I F+ T            F CC K+ 
Sbjct: 132 RAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCCTKDP 191

Query: 157 SEQV-----------QPTCPKELLGH-KNCIDEIETIISVKLQLIGIVGIGIAGLTIFGM 204
           +E V           +P   ++++ + K C+ + E  +   L ++  + IGIA L IFG+
Sbjct: 192 AEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFGI 251

Query: 205 IFSMVLCCAIRNSR 218
             +  L   I   R
Sbjct: 252 CLAQNLVSDIEAVR 265


>gi|50511934 transmembrane 4 superfamily member 17 isoform b [Homo
           sapiens]
          Length = 329

 Score = 79.0 bits (193), Expect = 3e-15
 Identities = 70/251 (27%), Positives = 108/251 (43%), Gaps = 47/251 (18%)

Query: 10  CIKYLLLGFNLLFWLAGSAVIAFGLW-FRFGGAIKELSSEDKSPEYFYVGLYVLVGAGAL 68
           C KY L GFN++FW+ G+  +A GLW +   G +  +S+         V L+V+VG   +
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGG--V 73

Query: 69  MMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAY 128
           M  +GF GC GA+RE+  +L  F   L +IF  E+ TG+ AF+ K      +        
Sbjct: 74  MSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNV 133

Query: 129 NDYLKD-------------------RGKGNGTL-ITFHST------------FQCCGKES 156
             Y  D                   RG  +  L I F+ T            F CC ++ 
Sbjct: 134 KAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDP 193

Query: 157 SEQVQPT-CPKEL-----------LGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGM 204
           +E V  T C  ++           +  K C+ + E  +   L ++  V +GIA L IFG+
Sbjct: 194 AEDVLNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGI 253

Query: 205 IFSMVLCCAIR 215
             +  L   I+
Sbjct: 254 CLAQNLVSDIK 264


>gi|54859560 transmembrane 4 superfamily member 17 isoform a [Homo
           sapiens]
          Length = 332

 Score = 77.8 bits (190), Expect = 7e-15
 Identities = 70/254 (27%), Positives = 108/254 (42%), Gaps = 50/254 (19%)

Query: 10  CIKYLLLGFNLLFWLAGSAVIAFGLW-FRFGGAIKELSSEDKSPEYFYVGLYVLVGAGAL 68
           C KY L GFN++FW+ G+  +A GLW +   G +  +S+         V L+V+VG   +
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGG--V 73

Query: 69  MMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAY 128
           M  +GF GC GA+RE+  +L  F   L +IF  E+ TG+ AF+ K      +        
Sbjct: 74  MSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNV 133

Query: 129 NDYLKD-------------------RGKGNGTL-ITFHST------------FQCCGKES 156
             Y  D                   RG  +  L I F+ T            F CC ++ 
Sbjct: 134 KAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDP 193

Query: 157 SEQVQPT-CPKEL--------------LGHKNCIDEIETIISVKLQLIGIVGIGIAGLTI 201
           +E V  T C  ++              +  K C+ + E  +   L ++  V +GIA L I
Sbjct: 194 AEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQI 253

Query: 202 FGMIFSMVLCCAIR 215
           FG+  +  L   I+
Sbjct: 254 FGICLAQNLVSDIK 267


>gi|54859505 transmembrane 4 superfamily member 17 isoform c [Homo
           sapiens]
          Length = 266

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 69/249 (27%), Positives = 106/249 (42%), Gaps = 50/249 (20%)

Query: 10  CIKYLLLGFNLLFWLAGSAVIAFGLW-FRFGGAIKELSSEDKSPEYFYVGLYVLVGAGAL 68
           C KY L GFN++FW+ G+  +A GLW +   G +  +S+         V L+V+VG   +
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGG--V 73

Query: 69  MMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAY 128
           M  +GF GC GA+RE+  +L  F   L +IF  E+ TG+ AF+ K      +        
Sbjct: 74  MSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNV 133

Query: 129 NDYLKD-------------------RGKGNGTL-ITFHST------------FQCCGKES 156
             Y  D                   RG  +  L I F+ T            F CC ++ 
Sbjct: 134 KAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDP 193

Query: 157 SEQVQPT-CPKEL--------------LGHKNCIDEIETIISVKLQLIGIVGIGIAGLTI 201
           +E V  T C  ++              +  K C+ + E  +   L ++  V +GIA L I
Sbjct: 194 AEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQI 253

Query: 202 FGMIFSMVL 210
           FG+  +  L
Sbjct: 254 FGICLAQNL 262


>gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]
          Length = 270

 Score = 75.5 bits (184), Expect = 3e-14
 Identities = 46/148 (31%), Positives = 72/148 (48%), Gaps = 4/148 (2%)

Query: 12  KYLLLGFNLLFWLAGSAVIAFGLW-FRFGGAIKELSSEDKSPEYFYVGLYVLVGAGALMM 70
           KYLL  +N++FWLAG   +  GLW +   G + +L+   +      V L ++VG   +M 
Sbjct: 16  KYLLFSYNIIFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVLVLMVGV--VMF 73

Query: 71  AVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYND 130
            +GF GC GA+RE+ C+L  F   +++IF  E+   V AF+ +       +  +E     
Sbjct: 74  TLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIKS 133

Query: 131 YLKDRGKGNGTLITFHSTFQCCGKESSE 158
           Y  D    N  + +     QCCG    E
Sbjct: 134 YRDDIDLQN-LIDSLQKANQCCGAYGPE 160


>gi|30425534 tetraspanin 33 [Homo sapiens]
          Length = 283

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 63/253 (24%), Positives = 103/253 (40%), Gaps = 55/253 (21%)

Query: 11  IKYLLLGFNLLFWLAGSAVIAFGLWFRF-GGAIKELSSEDKSPEYFYVGLYVLVGAGALM 69
           +KYLL  FN+LFW+    ++A G++ R    A   L+     P        +L+  G LM
Sbjct: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLAVDPAI------LLIVVGVLM 75

Query: 70  MAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYN 129
             + F GC G++RE+ C+L +F  CL  +F  ++  G+  F+    A   V  +   A  
Sbjct: 76  FLLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIV 135

Query: 130 DYLKDRGKGNGTLITF-HSTFQCCG----KESSEQVQPTCPKE----------------- 167
            Y  D    N  LI F    F CCG    K+ S+ +   C ++                 
Sbjct: 136 HYRDDLDLQN--LIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPT 193

Query: 168 ------------------------LLGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFG 203
                                   ++    CID++   I   L L+G V +G+A   + G
Sbjct: 194 PDQAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVG 253

Query: 204 MIFSMVLCCAIRN 216
           ++ S +L   I++
Sbjct: 254 ILLSQILVNQIKD 266


>gi|21265104 tetraspanin 7 [Homo sapiens]
          Length = 249

 Score = 72.0 bits (175), Expect = 4e-13
 Identities = 57/241 (23%), Positives = 103/241 (42%), Gaps = 46/241 (19%)

Query: 8   LRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFG-GAIKELSSEDKSPEYFYVGLYVLVGAG 66
           + C+K LL+ ++ +FW+ G  ++A G+W +   G    L +E+ +        YVL+G G
Sbjct: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTN-----APYVLIGTG 66

Query: 67  ALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRH-VQTMYE 125
             ++  G FGC    R S  +L  +   L ++F AE+  G+  F+      RH ++  + 
Sbjct: 67  TTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFV-----FRHEIKDTFL 121

Query: 126 EAYNDYLKD-RGKGNGTLITFH--STFQCCGKES-----------SEQVQPTC------- 164
             Y D ++   G    +    H   +  CCG ++              + P+C       
Sbjct: 122 RTYTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETDC 181

Query: 165 -PKEL---------LGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAI 214
            P++L         +  K C D + + +   + +I  V  GIA   + GM+ +   CC  
Sbjct: 182 NPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLA---CCLS 238

Query: 215 R 215
           R
Sbjct: 239 R 239


>gi|4502679 CD63 antigen isoform A [Homo sapiens]
          Length = 238

 Score = 72.0 bits (175), Expect = 4e-13
 Identities = 49/239 (20%), Positives = 104/239 (43%), Gaps = 28/239 (11%)

Query: 6   GGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGA 65
           GG++C+K+LL    L F      +IA G+  +    + +   +  +P        V++  
Sbjct: 5   GGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQL--VLSQTIIQGATPGSLLP--VVIIAV 60

Query: 66  GALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYE 125
           G  +  V F GCCGA +E+ C++ +F   L +I   EV   +  ++ +   +      + 
Sbjct: 61  GVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFR 120

Query: 126 EAYNDYLKDRGKGNGTLITFHSTFQCCG-----------KESSEQVQPTC---------- 164
           +   +Y K+    +  L    + F+CCG             S  +V  +C          
Sbjct: 121 QQMENYPKNNHTAS-ILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGI 179

Query: 165 --PKELLGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI 221
              ++ +  + C+++I   +   + ++    +GIA + + G++F+  L  +IR+  +V+
Sbjct: 180 NFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRSGYEVM 238


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.146    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,871,140
Number of Sequences: 37866
Number of extensions: 327255
Number of successful extensions: 904
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 783
Number of HSP's gapped (non-prelim): 64
length of query: 221
length of database: 18,247,518
effective HSP length: 98
effective length of query: 123
effective length of database: 14,536,650
effective search space: 1788007950
effective search space used: 1788007950
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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