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Search of human proteins with 209969800
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209969800 RPE-spondin [Homo sapiens]
(264 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209969800 RPE-spondin [Homo sapiens] 596 e-171
gi|169214870 PREDICTED: similar to hCG2041260 [Homo sapiens] 150 1e-36
gi|113429036 PREDICTED: hypothetical protein [Homo sapiens] 150 1e-36
gi|169214602 PREDICTED: similar to hCG2041260 [Homo sapiens] 150 1e-36
gi|110347423 spondin 1, extracellular matrix protein [Homo sapiens] 55 8e-08
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 52 7e-07
gi|150170672 thrombospondin, type I, domain containing 7A [Homo ... 51 9e-07
gi|134031945 SCO-spondin [Homo sapiens] 51 1e-06
gi|122937257 thrombospondin, type I, domain containing 7B [Homo ... 50 3e-06
gi|190341087 spondin 2, extracellular matrix protein [Homo sapiens] 49 6e-06
gi|6912682 spondin 2, extracellular matrix protein [Homo sapiens] 49 6e-06
gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 ... 47 1e-05
gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens] 47 2e-05
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 44 1e-04
gi|189242612 complement component 6 precursor [Homo sapiens] 43 3e-04
gi|169636415 complement component 6 precursor [Homo sapiens] 43 3e-04
gi|40317628 thrombospondin 2 precursor [Homo sapiens] 42 5e-04
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 41 0.001
gi|18490982 R-spondin 3 [Homo sapiens] 40 0.002
gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens] 39 0.006
gi|153792351 ADAM metallopeptidase with thrombospondin type 1 mo... 38 0.008
gi|110611170 ADAM metallopeptidase with thrombospondin type 1 mo... 38 0.010
gi|145699139 cartilage intermediate layer protein 2 [Homo sapiens] 38 0.010
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 37 0.023
gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens] 36 0.030
gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens] 36 0.030
gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens] 36 0.030
gi|4505737 complement factor properdin precursor [Homo sapiens] 36 0.039
gi|40317626 thrombospondin 1 precursor [Homo sapiens] 36 0.039
gi|147904700 semaphorin 5A [Homo sapiens] 36 0.039
>gi|209969800 RPE-spondin [Homo sapiens]
Length = 264
Score = 596 bits (1537), Expect = e-171
Identities = 264/264 (100%), Positives = 264/264 (100%)
Query: 1 MRTLWMALCALSRLWPGAQAGCAEAGRCCPGRDPACFARGWRLDRVYGTCFCDQACRFTG 60
MRTLWMALCALSRLWPGAQAGCAEAGRCCPGRDPACFARGWRLDRVYGTCFCDQACRFTG
Sbjct: 1 MRTLWMALCALSRLWPGAQAGCAEAGRCCPGRDPACFARGWRLDRVYGTCFCDQACRFTG 60
Query: 61 DCCFDYDRACPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAG 120
DCCFDYDRACPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAG
Sbjct: 61 DCCFDYDRACPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAG 120
Query: 121 CLEYSTPQGQDCGHTYVPAFITTSAFNKERTRQATSPHWSTHTEDAGYCMEFKTESLTPH 180
CLEYSTPQGQDCGHTYVPAFITTSAFNKERTRQATSPHWSTHTEDAGYCMEFKTESLTPH
Sbjct: 121 CLEYSTPQGQDCGHTYVPAFITTSAFNKERTRQATSPHWSTHTEDAGYCMEFKTESLTPH 180
Query: 181 CALENWPLTRWMQYLREGYTVCVDCQPPAMNSVSLRCSGDGLDSDGNQTLHWQAIGNPRC 240
CALENWPLTRWMQYLREGYTVCVDCQPPAMNSVSLRCSGDGLDSDGNQTLHWQAIGNPRC
Sbjct: 181 CALENWPLTRWMQYLREGYTVCVDCQPPAMNSVSLRCSGDGLDSDGNQTLHWQAIGNPRC 240
Query: 241 QGTWKKVRRVDQCSCPAVHSFIFI 264
QGTWKKVRRVDQCSCPAVHSFIFI
Sbjct: 241 QGTWKKVRRVDQCSCPAVHSFIFI 264
>gi|169214870 PREDICTED: similar to hCG2041260 [Homo sapiens]
Length = 412
Score = 150 bits (378), Expect = 1e-36
Identities = 79/204 (38%), Positives = 110/204 (53%), Gaps = 31/204 (15%)
Query: 75 CFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAGCLEYSTPQGQDCGH 134
C EW + C+ + V RR V QEP+NGG P P LEERAGC+EY + QG +C
Sbjct: 226 CGTVEWL--QSLCETCQVSYHVHRRRVLQEPRNGGVPFPLLEERAGCVEYWSHQGVECQQ 283
Query: 135 TY--------------VPAFITTSAFNKERTRQATSPHWSTHTEDAGYCMEFKTESLTPH 180
+ +PA ITT ++ KE W YC++F+ S+
Sbjct: 284 SLHEWGWAPGVALSGNIPALITTGSYGKE---------WEK------YCVQFQLGSIPGS 328
Query: 181 CALENWPLTRWMQYLREGYTVCVDCQPPAMNSVSLRCSGDGLDSDGNQTLHWQAIGNPRC 240
C P +W +YL +G+TVCV + PA ++ S RC GDG + GN+ WQA +PRC
Sbjct: 329 CGQARAPHAQWTRYLSQGHTVCVRSEWPAQDTRSRRCYGDGGGAKGNKMWLWQAASHPRC 388
Query: 241 QGTWKKVRRVDQCSCPAVHSFIFI 264
+GTW+K+ ++ CSCP VHS +FI
Sbjct: 389 RGTWEKLGQLRHCSCPVVHSLVFI 412
Score = 44.3 bits (103), Expect = 1e-04
Identities = 21/36 (58%), Positives = 21/36 (58%), Gaps = 6/36 (16%)
Query: 21 GCAEAGRCCPGRDPACFARGWRLDRVYGTCFCDQAC 56
G A GRCCPGRDP ARG CFCDQAC
Sbjct: 37 GSAALGRCCPGRDPMFVARG------PPRCFCDQAC 66
>gi|113429036 PREDICTED: hypothetical protein [Homo sapiens]
Length = 388
Score = 150 bits (378), Expect = 1e-36
Identities = 79/204 (38%), Positives = 110/204 (53%), Gaps = 31/204 (15%)
Query: 75 CFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAGCLEYSTPQGQDCGH 134
C EW + C+ + V RR V QEP+NGG P P LEERAGC+EY + QG +C
Sbjct: 202 CGTVEWL--QSLCETCQVSYHVHRRRVLQEPRNGGVPFPLLEERAGCVEYWSHQGVECQQ 259
Query: 135 TY--------------VPAFITTSAFNKERTRQATSPHWSTHTEDAGYCMEFKTESLTPH 180
+ +PA ITT ++ KE W YC++F+ S+
Sbjct: 260 SLHEWGWAPGVALSGNIPALITTGSYGKE---------WEK------YCVQFQLGSIPGS 304
Query: 181 CALENWPLTRWMQYLREGYTVCVDCQPPAMNSVSLRCSGDGLDSDGNQTLHWQAIGNPRC 240
C P +W +YL +G+TVCV + PA ++ S RC GDG + GN+ WQA +PRC
Sbjct: 305 CGQARAPHAQWTRYLSQGHTVCVRSEWPAQDTRSRRCYGDGGGAKGNKMWLWQAASHPRC 364
Query: 241 QGTWKKVRRVDQCSCPAVHSFIFI 264
+GTW+K+ ++ CSCP VHS +FI
Sbjct: 365 RGTWEKLGQLRHCSCPVVHSLVFI 388
Score = 44.3 bits (103), Expect = 1e-04
Identities = 21/36 (58%), Positives = 21/36 (58%), Gaps = 6/36 (16%)
Query: 21 GCAEAGRCCPGRDPACFARGWRLDRVYGTCFCDQAC 56
G A GRCCPGRDP ARG CFCDQAC
Sbjct: 37 GSAALGRCCPGRDPMFVARG------PPRCFCDQAC 66
>gi|169214602 PREDICTED: similar to hCG2041260 [Homo sapiens]
Length = 388
Score = 150 bits (378), Expect = 1e-36
Identities = 79/204 (38%), Positives = 110/204 (53%), Gaps = 31/204 (15%)
Query: 75 CFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAGCLEYSTPQGQDCGH 134
C EW + C+ + V RR V QEP+NGG P P LEERAGC+EY + QG +C
Sbjct: 202 CGTVEWL--QSLCETCQVSYHVHRRRVLQEPRNGGVPFPLLEERAGCVEYWSHQGVECQQ 259
Query: 135 TY--------------VPAFITTSAFNKERTRQATSPHWSTHTEDAGYCMEFKTESLTPH 180
+ +PA ITT ++ KE W YC++F+ S+
Sbjct: 260 SLHEWGWAPGVALSGNIPALITTGSYGKE---------WEK------YCVQFQLGSIPGS 304
Query: 181 CALENWPLTRWMQYLREGYTVCVDCQPPAMNSVSLRCSGDGLDSDGNQTLHWQAIGNPRC 240
C P +W +YL +G+TVCV + PA ++ S RC GDG + GN+ WQA +PRC
Sbjct: 305 CGQARAPHAQWTRYLSQGHTVCVRSEWPAQDTRSRRCYGDGGGAKGNKMWLWQAASHPRC 364
Query: 241 QGTWKKVRRVDQCSCPAVHSFIFI 264
+GTW+K+ ++ CSCP VHS +FI
Sbjct: 365 RGTWEKLGQLRHCSCPVVHSLVFI 388
Score = 44.3 bits (103), Expect = 1e-04
Identities = 21/36 (58%), Positives = 21/36 (58%), Gaps = 6/36 (16%)
Query: 21 GCAEAGRCCPGRDPACFARGWRLDRVYGTCFCDQAC 56
G A GRCCPGRDP ARG CFCDQAC
Sbjct: 37 GSAALGRCCPGRDPMFVARG------PPRCFCDQAC 66
>gi|110347423 spondin 1, extracellular matrix protein [Homo sapiens]
Length = 807
Score = 54.7 bits (130), Expect = 8e-08
Identities = 28/69 (40%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 60 GDCCFDYDRA-------CPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPC 112
GDC D ++ CP C + EWS WS C C +R R +Q EPQ GGAPC
Sbjct: 648 GDCNEDLEQVEKCMLPECPI-DCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPC 706
Query: 113 PPLEERAGC 121
P +R C
Sbjct: 707 PETVQRKKC 715
Score = 40.4 bits (93), Expect = 0.002
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 4/62 (6%)
Query: 60 GDCCFDYDRACPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERA 119
G C D D + C + EW WS C+ C R R R V+Q P++G P EE
Sbjct: 491 GPGCSDEDGST----CTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETE 546
Query: 120 GC 121
C
Sbjct: 547 KC 548
Score = 36.6 bits (83), Expect = 0.023
Identities = 30/131 (22%), Positives = 52/131 (39%), Gaps = 17/131 (12%)
Query: 75 CFVGEWSPWSGCADQ-CKPTTRVRRRSVQQEPQNGGAPCPPLEERAGCL--EYSTPQGQD 131
C WSPWS C+ C R+R+R ++ + + PCP ++ C+ S G
Sbjct: 443 CIYSNWSPWSACSSSTCDKGKRMRQRMLKAQ-LDLSVPCPDTQDFQPCMGPGCSDEDGST 501
Query: 132 CGH----TYVPAFITTSAFNKERTRQATSPHWSTHTEDAGYCM----EFKTESLTPHCAL 183
C T+ P I+ + R R + ED C E + ++ C+
Sbjct: 502 CTMSEWITWSPCSISCGMGMRSRER-----YVKQFPEDGSVCTLPTEETEKCTVNEECSP 556
Query: 184 ENWPLTRWMQY 194
+ +T W ++
Sbjct: 557 SSCLMTEWGEW 567
Score = 33.5 bits (75), Expect = 0.20
Identities = 13/39 (33%), Positives = 19/39 (48%)
Query: 70 CPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNG 108
C PC + WS WS C+ C R R+R ++ + G
Sbjct: 610 CHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELG 648
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 51.6 bits (122), Expect = 7e-07
Identities = 39/127 (30%), Positives = 55/127 (43%), Gaps = 12/127 (9%)
Query: 80 WSPWSGCADQCKPTTRVRRRS-VQQEPQNGGAPC-PPLEERAGCLEYSTP--QGQDCGHT 135
W PWS C+ C+ RVR+R+ EP+NGG PC E C + P C +
Sbjct: 859 WGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQACPVRGAWSCWTS 918
Query: 136 YVPAFITTSAFNKERTRQATSPHWSTHTEDAGYCMEFKTES---LTPHCALENW-PLTRW 191
+ P + + +RTR TSP S + C+ TE T C E W P + W
Sbjct: 919 WSPCSASCGGGHYQRTRSCTSPAPSPGED---ICLGLHTEEALCATQACP-EGWSPWSEW 974
Query: 192 MQYLREG 198
+ +G
Sbjct: 975 SKCTDDG 981
Score = 30.8 bits (68), Expect = 1.3
Identities = 48/235 (20%), Positives = 73/235 (31%), Gaps = 59/235 (25%)
Query: 70 CPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAGC-LEYSTPQ 128
CP P F W WS C+ C + RRR+ + G C GC +E+ T
Sbjct: 719 CPV-PIFWASWGSWSKCSSNCGGGMQSRRRACE-----NGNSC------LGCGVEFKTCN 766
Query: 129 GQDCGHT--------YVPAFITTSA----------------------FNKERTRQATSPH 158
+ C ++P +T F + RT T P
Sbjct: 767 PEGCPEVRRNTPWTPWLPVNVTQGGARQEQRFRFTCRAPLADPHGLQFGRRRTETRTCPA 826
Query: 159 WSTHTEDAGYCME--FKTESLTPHCALENW----PLTRWMQYLREGYTVCV-DCQPPAMN 211
+ + D +E ++ S +PH W P + + G+ V C P
Sbjct: 827 DGSGSCDTDALVEVLLRSGSTSPHTVSGGWAAWGPWSSCSRDCELGFRVRKRTCTNPEPR 886
Query: 212 SVSLRCSGDGLDSDGNQTLHWQAIGNPRCQGTWK---------KVRRVDQCSCPA 257
+ L C GD + G C +W +R C+ PA
Sbjct: 887 NGGLPCVGDAAEYQDCNPQACPVRGAWSCWTSWSPCSASCGGGHYQRTRSCTSPA 941
Score = 30.0 bits (66), Expect = 2.2
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 78 GEWSPWSG---CADQCKPTTRVRRRSVQQ-EPQNGGAPC 112
G W+PWS C+ C +VR+RS P++GG C
Sbjct: 665 GAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRIC 703
>gi|150170672 thrombospondin, type I, domain containing 7A [Homo
sapiens]
Length = 1657
Score = 51.2 bits (121), Expect = 9e-07
Identities = 24/64 (37%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
Query: 70 CPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAGCLEYS-TPQ 128
CP+ C + EWS WS C+ C +VR + ++++P NGG PCP L+ Y P
Sbjct: 1032 CPS-DCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPC 1090
Query: 129 GQDC 132
DC
Sbjct: 1091 HSDC 1094
Score = 48.1 bits (113), Expect = 8e-06
Identities = 22/51 (43%), Positives = 31/51 (60%), Gaps = 2/51 (3%)
Query: 70 CPARPCFVGEWSPWSGCADQCKPTTR-VRRRSVQQEPQNGGAPCPPLEERA 119
CP C + +WSPWS C+ C T + +RRR+V Q Q G PCP L +++
Sbjct: 1283 CPVN-CQLSDWSPWSECSQTCGLTGKMIRRRTVTQPFQGDGRPCPSLMDQS 1332
Score = 47.4 bits (111), Expect = 1e-05
Identities = 48/178 (26%), Positives = 65/178 (36%), Gaps = 51/178 (28%)
Query: 17 GAQAGCAEAGRCCPGRDPACFARGWRLDRVYGTCFCD----------------------- 53
G C P +PAC+ W+ R+ G C D
Sbjct: 554 GVTGNCPHLLEAIPCEEPACY--DWKAVRL-GNCEPDNGKECGPGTQVQEVVCINSDGEE 610
Query: 54 ---QACRFTGDCCFDYDRACPA---RPCFVGEWSPWSGCADQCKPTT----RVRRRSV-Q 102
Q CR D F AC A + C + WS WS C+ C T ++R RS+
Sbjct: 611 VDRQLCR---DAIFPIPVACDAPCPKDCVLSTWSTWSSCSHTCSGKTTEGKQIRARSILA 667
Query: 103 QEPQNGGAPCP---PLEERAGCLEY--------STPQGQDCGHTYVPAFITTSAFNKE 149
+ GG CP L+E C E+ + P GQ T V +F TT+ +N E
Sbjct: 668 YAGEEGGIRCPNSSALQEVRSCNEHPCTVYHWQTGPWGQCIEDTSVSSFNTTTTWNGE 725
Score = 46.2 bits (108), Expect = 3e-05
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
Query: 73 RPCFVGEWSPWSGCADQCKPT-----TRVRRRSVQQEPQNGGAPCPPLEERAGCL 122
+ C V EWS WS C+ C TRVR R+++Q P CP EE+ CL
Sbjct: 359 KECQVSEWSEWSPCSKTCHDMVSPAGTRVRTRTIRQFPIGSEKECPEFEEKEPCL 413
Score = 42.7 bits (99), Expect = 3e-04
Identities = 27/81 (33%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Query: 75 CFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAGCLEYSTPQGQDCGH 134
C V E+S WS C+ C + R R V PQ GG+ CP L E C + S + ++ +
Sbjct: 195 CIVSEFSAWSECSKTCGSGLQHRTRHVVAPPQFGGSGCPNLTEFQVC-QSSPCEAEELRY 253
Query: 135 T-YVPAFITTSAFNKERTRQA 154
+ +V + T S + + RQA
Sbjct: 254 SLHVGPWSTCSMPHSRQVRQA 274
Score = 37.7 bits (86), Expect = 0.010
Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 2/53 (3%)
Query: 70 CPARPCFVGEWSPWSGCADQCKPTT-RVRRRSVQQEPQNGGAPCPPLEERAGC 121
CP C + EW PW+ C C ++ R R ++P + G CP E+ C
Sbjct: 1162 CP-EDCVISEWGPWTQCVLPCNQSSFRQRSADPIRQPADEGRSCPNAVEKEPC 1213
Score = 35.4 bits (80), Expect = 0.051
Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 6/55 (10%)
Query: 73 RPCFVGEWSPWSGCADQCKP-----TTRVRRRSVQQEPQNGGAPC-PPLEERAGC 121
+ C V +S W+ C CK + R R + Q P NGG C PL E C
Sbjct: 770 KDCIVTPYSDWTSCPSSCKEGDSSIRKQSRHRVIIQLPANGGRDCTDPLYEEKAC 824
Score = 32.3 bits (72), Expect = 0.44
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Query: 65 DYDRACPARPCF---VGEWSPWSGCADQCKPTTRVRRRS 100
D + CP +PC+ G+WSP QC TR R S
Sbjct: 1330 DQSKPCPVKPCYRWQYGQWSPCQVQEAQCGEGTRTRNIS 1368
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 50.8 bits (120), Expect = 1e-06
Identities = 37/96 (38%), Positives = 45/96 (46%), Gaps = 10/96 (10%)
Query: 48 GTCFCDQACRFTGDCCFDYDRACPARPCFVGEWSPWSGCADQCKPTTRVRRRS-VQQEPQ 106
G+C D RF CF +ACP + W W C+ C + R+RS V P+
Sbjct: 2535 GSCPRD---RFRSQSCFV--QACPVAGAWA-MWEAWGPCSVSCGGGHQSRQRSCVDPPPK 2588
Query: 107 NGGAPCP-PLEERAGCLEYSTPQGQDC--GHTYVPA 139
NGGAPCP +ERA C G DC G YV A
Sbjct: 2589 NGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSA 2624
Score = 42.7 bits (99), Expect = 3e-04
Identities = 26/65 (40%), Positives = 29/65 (44%), Gaps = 12/65 (18%)
Query: 68 RACPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEP-QNGGAPCP----------PLE 116
RACP P WSPWS C C +R RS P +NGGAPC P+
Sbjct: 3999 RACPV-PGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMP 4057
Query: 117 ERAGC 121
AGC
Sbjct: 4058 CEAGC 4062
Score = 42.0 bits (97), Expect = 5e-04
Identities = 27/76 (35%), Positives = 34/76 (44%), Gaps = 12/76 (15%)
Query: 63 CFDYDRACPARPCFV-GEWSPWSG---CADQCKPTTRVRRRSVQ-QEPQNGGAPCP---- 113
C + C PC V G W PWS C+ C+ TR R R+ PQ+GGAPC
Sbjct: 3393 CLEGRLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAG 3452
Query: 114 ---PLEERAGCLEYST 126
+R C Y+T
Sbjct: 3453 EAGAQHQREACPSYAT 3468
Score = 39.7 bits (91), Expect = 0.003
Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 16/118 (13%)
Query: 15 WPGAQAGCAEAGRCCPGRDPACFARGWR-LDRVYGTCFCDQACRFTGDCCFDYDRACPAR 73
W C G+ GR C G L G QAC FT C D + +
Sbjct: 1703 WGPCSRTCGPWGQ---GRSRRCSPLGLLVLQNCPGPEHQSQAC-FTAACPVDGEWST--- 1755
Query: 74 PCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAGCLEYSTPQGQD 131
WSPWS C++ C+ T +R+ PQNGG C L + P QD
Sbjct: 1756 ------WSPWSVCSEPCRGTMTRQRQC--HSPQNGGRTCAALPGGLHSTRQTKPCPQD 1805
Score = 39.7 bits (91), Expect = 0.003
Identities = 32/103 (31%), Positives = 38/103 (36%), Gaps = 14/103 (13%)
Query: 26 GRCCPGRDPACFA----RGWRLDRVYGTCFCDQACRFTGDCCFDYDRACPARPCFV-GEW 80
GRC P C W L Q C C + CP + C V G W
Sbjct: 4715 GRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCT-----CVNESLVCPHQECPVLGPW 4769
Query: 81 SPWSGCADQCKPTTRVRRRSVQQEPQNGGAPC--PPLEERAGC 121
S WS C+ C T R R+ + P G APC E+R C
Sbjct: 4770 SAWSSCSAPCGGGTMERHRTCEGGP--GVAPCQAQDTEQRQEC 4810
Score = 38.1 bits (87), Expect = 0.008
Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 3/73 (4%)
Query: 61 DCCFDYDRACPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAG 120
+ C Y CP + G W PWS C D C + R + GG PCP ++
Sbjct: 3461 EACPSY-ATCPVDGAW-GPWGPWSPC-DMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSR 3517
Query: 121 CLEYSTPQGQDCG 133
+ ++ Q DCG
Sbjct: 3518 PCQENSTQCTDCG 3530
Score = 37.4 bits (85), Expect = 0.014
Identities = 22/54 (40%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 70 CPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQN-GGAPCP-PLEERAGC 121
CP PC WS W+ C C R R RS P GGAPC +E GC
Sbjct: 2712 CPL-PCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGC 2764
Score = 36.2 bits (82), Expect = 0.030
Identities = 48/217 (22%), Positives = 62/217 (28%), Gaps = 47/217 (21%)
Query: 15 WPGAQAGC--------AEAGRCCPGRDPACF---ARGWRLDRVYGTC---FCDQA----C 56
WP GC G C R C AR W R+ C C C
Sbjct: 1841 WPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRC 1900
Query: 57 RFTGDCCFDYDRACPARPCFVGEWSPWSGCADQC--KPTTRVRRRSVQQEPQNGGAPCPP 114
R DC D C WSPW+ C C + R S P G C
Sbjct: 1901 RLNPDCAVD---------CGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRG 1951
Query: 115 LEERAGCLEYSTPQGQDCGHTYVPAFITTSAFNKERTRQATSPHWSTHTEDAGYCMEFKT 174
+ +A + +G C H + W C+ T
Sbjct: 1952 IHRKARRCQTEPCEG--CEH--------------QGQVHRVGERWHGGPCRVCQCLHNLT 1995
Query: 175 ESLTPHCALENWPLTRWMQYLREGYTVCVDCQPPAMN 211
+P+C L + P W+ G + C C P N
Sbjct: 1996 AHCSPYCPLGSCP-QGWVLVEGTGES-CCHCALPGEN 2030
Score = 36.2 bits (82), Expect = 0.030
Identities = 47/175 (26%), Positives = 63/175 (36%), Gaps = 27/175 (15%)
Query: 22 CAEAGRCCPG---RDPACFARGWRLDRVYGTCFCDQACRFTGDC----CFDYDRACPARP 74
CA C PG + +C R +++G + A C C AC +
Sbjct: 2922 CAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSER 2981
Query: 75 CFVG-EWSPW---SGCADQCKPTTRVRRRSVQQEPQN-GGAPC--PPLEERAGCLEYSTP 127
C V WSPW S C+ C R R R+ P GGA C P +E L
Sbjct: 2982 CPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCPG 3041
Query: 128 QGQDCGHTYVPAFITTSAFNKERTRQATSPHWSTHTEDAGYCMEFKTESLTPHCA 182
G + G + P + + RTR ++ MEF T L P CA
Sbjct: 3042 PGGEWG-PWSPCSVPCGGGYRNRTRGSSRS-----------LMEFSTCGLQP-CA 3083
Score = 35.4 bits (80), Expect = 0.051
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 21/81 (25%)
Query: 70 CPARPCFV--GEWSPWSGCADQC----KPTTRVRRRSVQQEPQNGGAPCP-------PLE 116
C RPC GEW PWS C+ C + TR RS+ + G PC P +
Sbjct: 3034 CSLRPCPGPGGEWGPWSPCSVPCGGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPRD 3093
Query: 117 ER--------AGCLEYSTPQG 129
++ A C E S P+G
Sbjct: 3094 KQWLDCAQGPASCAELSAPRG 3114
Score = 34.7 bits (78), Expect = 0.088
Identities = 33/125 (26%), Positives = 45/125 (36%), Gaps = 26/125 (20%)
Query: 2 RTLWMALCALSRLWPGAQAGCAEAGRCCPGRDPACFARGWRLDRVYGTCFCDQACRFTGD 61
R L M L +L LW + PG PA A C Q +G+
Sbjct: 2427 RNLLMWLPSLPALWAASTVPFMMPTMALPGL-PASRA----------LCSPSQLSCGSGE 2475
Query: 62 CCFDYDRACPARP-------------CFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNG 108
C +R C RP C + WS WS C+ C +R+ + + P G
Sbjct: 2476 C-LSAERRCDLRPDCQDGSDEDGCVDCVLAPWSVWSSCSRSCGLGLTFQRQELLRPPLPG 2534
Query: 109 GAPCP 113
G+ CP
Sbjct: 2535 GS-CP 2538
Score = 33.9 bits (76), Expect = 0.15
Identities = 31/112 (27%), Positives = 39/112 (34%), Gaps = 23/112 (20%)
Query: 3 TLWMALCALSRLWPGAQAGCAEAGRCCPGR-DPACFARGWRLDRVYGTCFCDQACRFTGD 61
T W + C+ S L PG G R CP D +C G ++ C
Sbjct: 2779 TSWSS-CSQSCLAPGGGPGWRSRSRLCPSPGDSSC----------PGDATQEEPCS---- 2823
Query: 62 CCFDYDRACPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCP 113
CP P G W+PWS C+ C + R RS G CP
Sbjct: 2824 -----PPVCPV-PSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAP-GDTTCP 2868
Score = 33.9 bits (76), Expect = 0.15
Identities = 17/51 (33%), Positives = 22/51 (43%), Gaps = 5/51 (9%)
Query: 70 CPARPCFVGE-----WSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPL 115
C + PC GE W+PWS C+ C P R R + P + PL
Sbjct: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPL 3224
Score = 33.5 bits (75), Expect = 0.20
Identities = 29/105 (27%), Positives = 35/105 (33%), Gaps = 18/105 (17%)
Query: 29 CPGRDPACFARGWR---------LDRVYGTCFC-----DQACRFTG---DCCFDYDRACP 71
CPG AC W L G+C C D C T D Y CP
Sbjct: 4304 CPGLLEACSWGPWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSGPCP 4363
Query: 72 ARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLE 116
C WS W+ C+ + R R + GAPC L+
Sbjct: 4364 EE-CVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLD 4407
Score = 33.1 bits (74), Expect = 0.26
Identities = 13/31 (41%), Positives = 15/31 (48%)
Query: 78 GEWSPWSGCADQCKPTTRVRRRSVQQEPQNG 108
G W PWS C+ C R R R+ Q P G
Sbjct: 3256 GPWGPWSHCSRSCGGGLRSRTRACDQPPPQG 3286
Score = 33.1 bits (74), Expect = 0.26
Identities = 27/103 (26%), Positives = 33/103 (32%), Gaps = 15/103 (14%)
Query: 21 GCAEAGRC-CPGRDPACFARGWRLDRVYGTCFCDQACRFTGDCCFDYDRACPARPCFVGE 79
GC G C C +A G + C C G P C
Sbjct: 4110 GCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQ-----AGQLSCTAQPCPPPTHCAWSH 4164
Query: 80 WSPWSGCADQCKPTTRVRR-RSVQ--------QEPQNGGAPCP 113
WS WS C+ C P + R RS +E Q+ PCP
Sbjct: 4165 WSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCP 4207
Score = 32.7 bits (73), Expect = 0.33
Identities = 22/60 (36%), Positives = 24/60 (40%), Gaps = 14/60 (23%)
Query: 69 ACPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQ------------QEPQNGGAPCPPLE 116
ACP C W PWS C C R+R R + QE NGG PCP E
Sbjct: 4611 ACPDS-CQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGG-PCPECE 4668
Score = 31.6 bits (70), Expect = 0.74
Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 5/56 (8%)
Query: 70 CPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPL----EERAGC 121
C A C W+PW C+ C + RR + P GG CP + +ER C
Sbjct: 3942 CGAGNCSWTSWAPWEPCSRSC-GVGQQRRLRAYRPPGPGGHWCPNILTAYQERRFC 3996
Score = 29.6 bits (65), Expect = 2.8
Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 8/61 (13%)
Query: 60 GDC-CFDYDRACPARPCF-----VGEWSPWSGCADQCKPT-TRVR-RRSVQQEPQNGGAP 111
G+C C +C CF G WSPW C+ C TR R R+ V P G
Sbjct: 3791 GNCSCAHGKLSCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQG 3850
Query: 112 C 112
C
Sbjct: 3851 C 3851
Score = 29.6 bits (65), Expect = 2.8
Identities = 19/60 (31%), Positives = 22/60 (36%), Gaps = 4/60 (6%)
Query: 78 GEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEER----AGCLEYSTPQGQDCG 133
G WS WS C+ C R RS + PL+ER C E G CG
Sbjct: 3884 GPWSSWSPCSRSCTDPARPAWRSRTRLCLANCTMGDPLQERPCNLPSCTELPVCPGPGCG 3943
Score = 28.5 bits (62), Expect = 6.3
Identities = 19/62 (30%), Positives = 24/62 (38%), Gaps = 9/62 (14%)
Query: 60 GDC----CFDYDRACPARPCFVGE----WSPWSGCADQCKPTTRVRRRSVQ-QEPQNGGA 110
G+C C C C V E WS WS C C +VR R+ + P +
Sbjct: 4231 GECQRCSCTPEGVICEDTECAVPEAWTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHRSP 4290
Query: 111 PC 112
PC
Sbjct: 4291 PC 4292
Score = 28.1 bits (61), Expect = 8.2
Identities = 17/61 (27%), Positives = 22/61 (36%), Gaps = 1/61 (1%)
Query: 70 CPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAGCLEYSTPQG 129
CP P W PW C+ C ++R R + P G A C E P G
Sbjct: 3642 CPD-PGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAG 3700
Query: 130 Q 130
+
Sbjct: 3701 R 3701
>gi|122937257 thrombospondin, type I, domain containing 7B [Homo
sapiens]
Length = 1577
Score = 49.7 bits (117), Expect = 3e-06
Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 8/98 (8%)
Query: 19 QAGCAEAGRCCPGRDPACFARGWRLDRVYGTCFCDQACRFTGDCCFDYDRACPARPCFVG 78
QA E G R AC + R FC + C CP C +
Sbjct: 922 QADSKECGEGLRFRAVACSDKN---GRPVDPSFCSSSGYIQEKCVIP----CPF-DCKLS 973
Query: 79 EWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLE 116
+WS W C+ C R+R + ++++P NGG PCP L+
Sbjct: 974 DWSSWGSCSSSCGIGVRIRSKWLKEKPYNGGRPCPKLD 1011
Score = 46.2 bits (108), Expect = 3e-05
Identities = 25/63 (39%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Query: 70 CPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAGC-LEYSTPQ 128
CP R C V E+ PWS C+ C + R R+V P GG CP L E C S P
Sbjct: 145 CP-RDCVVSEFLPWSNCSKGCGKKLQHRTRAVIAPPLFGGLQCPNLTESRACDAPISCPL 203
Query: 129 GQD 131
G++
Sbjct: 204 GEE 206
Score = 45.4 bits (106), Expect = 5e-05
Identities = 46/176 (26%), Positives = 59/176 (33%), Gaps = 46/176 (26%)
Query: 17 GAQAGCAEAGRCCPGRDPACFARGWRLDRVYGTCF-----CDQACRFTGDCCFDYDRA-- 69
G C P DP C+ W G CF C R C + DR
Sbjct: 492 GPAGHCPHLVESVPCEDPMCYR--WLASE--GICFPDHGKCGLGHRILKAVCQN-DRGED 546
Query: 70 -----CPARP--------------CFVGEWSPWSGCADQCKPTT----RVRRRSVQQEPQ 106
CP P C + EW+ WS C+ C + R R++
Sbjct: 547 VSGSLCPVPPPPERKSCEIPCRMDCVLSEWTEWSSCSQSCSNKNSDGKQTRSRTILALAG 606
Query: 107 NGGAPCPP---LEERAGCLEYS--------TPQGQDCGHTYVPAFITTSAFNKERT 151
GG PCPP L+E C ++S +P G T V A T +N E T
Sbjct: 607 EGGKPCPPSQALQEHRLCNDHSCMQLHWETSPWGPCSEDTLVTALNATIGWNGEAT 662
Score = 42.0 bits (97), Expect = 5e-04
Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 5/55 (9%)
Query: 73 RPCFVGEWSPWSGCADQCK-----PTTRVRRRSVQQEPQNGGAPCPPLEERAGCL 122
+ C +WS WS C+ C+ P R R R+V+ GG CP L E+ C+
Sbjct: 304 KDCETSQWSSWSPCSKTCRSGSLLPGFRSRSRNVKHMAIGGGKECPELLEKEACI 358
Score = 33.9 bits (76), Expect = 0.15
Identities = 25/76 (32%), Positives = 31/76 (40%), Gaps = 13/76 (17%)
Query: 63 CFDYDRACPARPCF--------VGEWSPWSGCADQCKP----TTRVRRRSVQQEPQNGGA 110
C D R RPCF V +S W+ C C+ + R R + QE NGG
Sbjct: 687 CPDSTRPETVRPCFLPCKKDCIVTAFSEWTPCPRMCQAGNATVKQSRYRIIIQEAANGGQ 746
Query: 111 PCP-PLEERAGCLEYS 125
CP L E C + S
Sbjct: 747 ECPDTLYEERECEDVS 762
Score = 33.9 bits (76), Expect = 0.15
Identities = 17/53 (32%), Positives = 19/53 (35%), Gaps = 1/53 (1%)
Query: 70 CPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAGCL 122
CP C + EW WS C C P T RR P C + CL
Sbjct: 1095 CP-NECVMSEWGLWSKCPQSCDPHTMQRRTRHLLRPSLNSRTCAEDSQVQPCL 1146
Score = 32.7 bits (73), Expect = 0.33
Identities = 21/77 (27%), Positives = 30/77 (38%), Gaps = 12/77 (15%)
Query: 49 TCFCDQACRFTGDCCFDYDRACPAR---PCFV--------GEWSPWSGCADQCKPTTRV- 96
+C C + D C ++ P R PC V W+ W+ C+ C R+
Sbjct: 1182 SCVCSDGKPVSMDQCEQHNLEKPQRMSIPCLVECVVNCQLSGWTAWTECSQTCGHGGRMS 1241
Query: 97 RRRSVQQEPQNGGAPCP 113
R R + Q G PCP
Sbjct: 1242 RTRFIIMPTQGEGRPCP 1258
Score = 31.2 bits (69), Expect = 0.97
Identities = 18/53 (33%), Positives = 19/53 (35%), Gaps = 6/53 (11%)
Query: 75 CFVGEWSPWSGCAD------QCKPTTRVRRRSVQQEPQNGGAPCPPLEERAGC 121
C V WS W C Q K R R+R V E CP L E C
Sbjct: 454 CIVSSWSAWGLCIHENCHDPQGKKGFRTRQRHVLMESTGPAGHCPHLVESVPC 506
>gi|190341087 spondin 2, extracellular matrix protein [Homo sapiens]
Length = 331
Score = 48.5 bits (114), Expect = 6e-06
Identities = 22/49 (44%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 75 CFVGEWSPWSGCADQC-KPTTRVRRRSVQQEPQNGGAPCPPLEERAGCL 122
C V WS W C C + T+ R R V+ +P N G+PCP LEE A C+
Sbjct: 278 CEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAECV 326
>gi|6912682 spondin 2, extracellular matrix protein [Homo sapiens]
Length = 331
Score = 48.5 bits (114), Expect = 6e-06
Identities = 22/49 (44%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 75 CFVGEWSPWSGCADQC-KPTTRVRRRSVQQEPQNGGAPCPPLEERAGCL 122
C V WS W C C + T+ R R V+ +P N G+PCP LEE A C+
Sbjct: 278 CEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAECV 326
>gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1
[Homo sapiens]
Length = 925
Score = 47.4 bits (111), Expect = 1e-05
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 12/71 (16%)
Query: 3 TLWMALCALSRLWP---GAQAGCAEAGRCCPGRDPACFARGWRLDRVYGTCFCDQACRFT 59
+L +++C L+ + G + CA+ + C GR CF +R +G C CD AC
Sbjct: 79 SLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGR---CF------ERTFGNCRCDAACVEL 129
Query: 60 GDCCFDYDRAC 70
G+CC DY C
Sbjct: 130 GNCCLDYQETC 140
Score = 38.1 bits (87), Expect = 0.008
Identities = 19/70 (27%), Positives = 24/70 (34%), Gaps = 10/70 (14%)
Query: 20 AGCAEAGRCCPGRDPACFARG--WRLDR--------VYGTCFCDQACRFTGDCCFDYDRA 69
A C E G CC C W ++ C C C+ GDCC +Y
Sbjct: 124 AACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINYSSV 183
Query: 70 CPARPCFVGE 79
C +V E
Sbjct: 184 CQGEKSWVEE 193
>gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]
Length = 1522
Score = 47.0 bits (110), Expect = 2e-05
Identities = 52/184 (28%), Positives = 75/184 (40%), Gaps = 29/184 (15%)
Query: 79 EWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPC--PPLEERAGCLEYSTPQGQ-DCGHT 135
EWSPWS C+ C R R RS PQ GG PC P + + GQ +
Sbjct: 350 EWSPWSLCSFTCGRGQRTRTRSC-TPPQYGGRPCEGPETHHKPCNIALCPVDGQWQEWSS 408
Query: 136 YVPAFITTSAFNKERTRQATSPHWSTH--TEDAGYCMEFKTESLTPHCALENWPLTRWMQ 193
+ +T S ++R+RQ T+ + H +E G E + E P C +W Q
Sbjct: 409 WSQCSVTCSNGTQQRSRQCTA---AAHGGSECRGPWAESR-ECYNPECTANG----QWNQ 460
Query: 194 YLREGYTVCVDCQPPAMNSVSLRCSGDGLDSDGNQTLHWQAIGNPRCQGTWKKVRRVDQC 253
+ G+ + S C DG +T I +C+GT ++VRR +
Sbjct: 461 W---GH----------WSGCSKSC--DGGWERRIRTCQGAVITGQQCEGTGEEVRRCSEQ 505
Query: 254 SCPA 257
CPA
Sbjct: 506 RCPA 509
>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor
[Homo sapiens]
Length = 1584
Score = 43.9 bits (102), Expect = 1e-04
Identities = 49/197 (24%), Positives = 75/197 (38%), Gaps = 31/197 (15%)
Query: 70 CPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEER------AGCLE 123
CP + EWSPWS C+ C R R R+ + PQ GG PC E++ A C
Sbjct: 406 CPVHGAW-DEWSPWSLCSSTCGRGFRDRTRTC-RPPQFGGNPCEGPEKQTKFCNIALCPG 463
Query: 124 YSTPQGQDCGHTYVPAFITTSAFNKERTRQATSPHWSTHTEDAGYCMEFKTESLTPHCAL 183
+ + ++ + S ++RTR+ P + E G+ +E T C L
Sbjct: 464 RAVDGNWNEWSSWSACSASCSQGRQQRTRECNGPSYG-GAECQGHWVE------TRDCFL 516
Query: 184 ENWPLT-RWMQYLREGYTVCVDCQPPAMNSVSLRCSGDGLDSDGNQTLHWQAIGNPRCQG 242
+ P+ +W + G + V C + + CSG G CQG
Sbjct: 517 QQCPVDGKWQAWASWG-SCSVTCGAGSQRRERV-CSG-------------PFFGGAACQG 561
Query: 243 TWKKVRRVDQCSCPAVH 259
+ R+ CP H
Sbjct: 562 PQDEYRQCGTQRCPEPH 578
Score = 32.7 bits (73), Expect = 0.33
Identities = 42/186 (22%), Positives = 63/186 (33%), Gaps = 32/186 (17%)
Query: 79 EWSPWSGCADQCKPTTRVRRR---SVQQEPQNGGAPCPPLEERAGCLEYSTPQGQDCGHT 135
EWSPWS C+ C + R R S Q G PL E+ C +
Sbjct: 359 EWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSG----PLREQRLCNNSAVCPVHGAWDE 414
Query: 136 YVPAFITTSAFN---KERTRQATSPHWSTH-TEDAGYCMEFKTESLTPHCALE-NWPLTR 190
+ P + +S ++RTR P + + E +F +L P A++ NW
Sbjct: 415 WSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFCNIALCPGRAVDGNW--NE 472
Query: 191 WMQYLREGYTVCVDCQPPAMNSVSLRCSGDGLDSDGNQTLHWQAIGNPRCQGTWKKVRRV 250
W ++ C + C+G + G CQG W + R
Sbjct: 473 W-----SSWSACSASCSQGRQQRTRECNG-------------PSYGGAECQGHWVETRDC 514
Query: 251 DQCSCP 256
CP
Sbjct: 515 FLQQCP 520
>gi|189242612 complement component 6 precursor [Homo sapiens]
Length = 934
Score = 42.7 bits (99), Expect = 3e-04
Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 8/72 (11%)
Query: 43 LDRVYGTCFCDQAC--RFTGDCCFDYDRACPARPCFVGEWSPWSGCADQCKPTTRVRRRS 100
+D+ Y FC+Q C + T +C + + CP C +G++ PWS C + ++V RS
Sbjct: 52 VDKYYQENFCEQICSKQETRECNW---QRCPIN-CLLGDFGPWSDCDPCIEKQSKV--RS 105
Query: 101 VQQEPQNGGAPC 112
V + Q GG PC
Sbjct: 106 VLRPSQFGGQPC 117
>gi|169636415 complement component 6 precursor [Homo sapiens]
Length = 934
Score = 42.7 bits (99), Expect = 3e-04
Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 8/72 (11%)
Query: 43 LDRVYGTCFCDQAC--RFTGDCCFDYDRACPARPCFVGEWSPWSGCADQCKPTTRVRRRS 100
+D+ Y FC+Q C + T +C + + CP C +G++ PWS C + ++V RS
Sbjct: 52 VDKYYQENFCEQICSKQETRECNW---QRCPIN-CLLGDFGPWSDCDPCIEKQSKV--RS 105
Query: 101 VQQEPQNGGAPC 112
V + Q GG PC
Sbjct: 106 VLRPSQFGGQPC 117
>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
Length = 1172
Score = 42.0 bits (97), Expect = 5e-04
Identities = 25/66 (37%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
Query: 68 RACPARPCFV----GEWSPWSGCADQCKPTTRVRRRSVQQ-EPQNGGAPC-PPLEERAGC 121
+AC PC + WSPWS C C R R R EPQ GG C ++ER C
Sbjct: 484 KACQGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMC 543
Query: 122 LEYSTP 127
+ S P
Sbjct: 544 NKRSCP 549
Score = 33.5 bits (75), Expect = 0.20
Identities = 34/130 (26%), Positives = 43/130 (33%), Gaps = 25/130 (19%)
Query: 48 GTCFCDQACRFTGDCCFD---YDRACPARPCFV--------GEWSPWSGCADQCKPTTRV 96
GT ++C T + C RAC C WSPWS C+ C
Sbjct: 400 GTQQRGRSCDVTSNTCLGPSIQTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNIT 459
Query: 97 RRRSVQQE-PQNGGAPCPPLEERAGCLEYSTPQGQDC--------GHTYVPAFITTSAFN 147
R R PQ GG C + E QG C + +T +
Sbjct: 460 RIRLCNSPVPQMGGKNC-----KGSGRETKACQGAPCPIDGRWSPWSPWSACTVTCAGGI 514
Query: 148 KERTRQATSP 157
+ERTR SP
Sbjct: 515 RERTRVCNSP 524
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 41.2 bits (95), Expect = 0.001
Identities = 54/221 (24%), Positives = 86/221 (38%), Gaps = 38/221 (17%)
Query: 47 YGTCFCDQACRFTGDCCFDYDRACPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQ 106
YGT C R T C + CP + EW WS C+ C +R R R+ PQ
Sbjct: 341 YGT-LCSGPLRETRPC--NNSATCPVHGVWE-EWGSWSLCSRSCGRGSRSRMRTCVP-PQ 395
Query: 107 NGGAPC--PPLEERAGCLEYSTPQGQ--DCGHTYVPAFITTSAFNKERTRQAT--SPHWS 160
+GG C P L+ + + +GQ + G + P + + ++R+R+ + P W+
Sbjct: 396 HGGKACEGPELQTKLCSMAACPVEGQWLEWG-PWGPCSTSCANGTQQRSRKCSVAGPAWA 454
Query: 161 THTEDAGYCMEFKTESLTPHCALENWPLT--RWMQYLREGYTVCVDCQPPAMNSVSLRCS 218
T C T+ T C+ P T +W + +++C C
Sbjct: 455 T-------CTGALTD--TRECSNLECPATDSKWGPW--NAWSLCSKTCDTGWQRRFRMCQ 503
Query: 219 GDGLDSDGNQTLHWQAIGNPRCQGTWKKVRRVDQCSCPAVH 259
G G P C+GT ++V+ + CPA H
Sbjct: 504 ATGTQ------------GYP-CEGTGEEVKPCSEKRCPAFH 531
Score = 33.9 bits (76), Expect = 0.15
Identities = 20/49 (40%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Query: 79 EWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCP-PLEERAGCLEYST 126
EWSPWS C+ C +VR RS P G C PL E C +T
Sbjct: 314 EWSPWSVCSLTCGQGLQVRTRSCVSSPY--GTLCSGPLRETRPCNNSAT 360
Score = 31.6 bits (70), Expect = 0.74
Identities = 28/88 (31%), Positives = 34/88 (38%), Gaps = 6/88 (6%)
Query: 52 CDQACRFTGDCCFDYDRACPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAP 111
C A T +C + CPA G W+ WS C+ C T RR + Q G P
Sbjct: 456 CTGALTDTRECS---NLECPATDSKWGPWNAWSLCSKTC-DTGWQRRFRMCQATGTQGYP 511
Query: 112 CPPL-EERAGCLEYSTPQGQD-CGHTYV 137
C EE C E P + C YV
Sbjct: 512 CEGTGEEVKPCSEKRCPAFHEMCRDEYV 539
>gi|18490982 R-spondin 3 [Homo sapiens]
Length = 272
Score = 40.4 bits (93), Expect = 0.002
Identities = 20/52 (38%), Positives = 23/52 (44%), Gaps = 5/52 (9%)
Query: 75 CFVGEWSPWSGCADQCKPT-----TRVRRRSVQQEPQNGGAPCPPLEERAGC 121
C V EW+PWS C + K T R R + Q P G CPP E C
Sbjct: 148 CEVSEWNPWSPCTKKGKTCGFKRGTETRVREIIQHPSAKGNLCPPTNETRKC 199
>gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]
Length = 476
Score = 38.5 bits (88), Expect = 0.006
Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 6/62 (9%)
Query: 28 CCPGRDPACFARGWRLDRVYGTCFCDQAC-RFTGDCCFDYDRACPARPCFVGEWSPW--S 84
CC RD C + + + C+CD+ C R DCC DY C + PW
Sbjct: 62 CCEDRDDGCVTEFYAANAL---CYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWYPE 118
Query: 85 GC 86
GC
Sbjct: 119 GC 120
>gi|153792351 ADAM metallopeptidase with thrombospondin type 1
motif, 8 preproprotein [Homo sapiens]
Length = 889
Score = 38.1 bits (87), Expect = 0.008
Identities = 34/119 (28%), Positives = 46/119 (38%), Gaps = 10/119 (8%)
Query: 18 AQAGCAEAGRCCPGRDPACFARGWRLDRVYGT-CFCDQACRFTGDCC--FDYDRACPARP 74
AQ CA+ G +P C + L GT C C G C + +R P
Sbjct: 468 AQDVCAQLWCHTDGAEPLCHTKNGSLPWADGTPCGPGHLCS-EGSCLPEEEVERPKPVAD 526
Query: 75 CFVGEWSPWSGCADQCKPTTRVRRRSVQQ-EPQNGGAPCPPLEERAGCLEYSTPQGQDC 132
W PW C+ C + R + EPQNGG C L RA +Y + ++C
Sbjct: 527 GGWAPWGPWGECSRTCGGGVQFSHRECKDPEPQNGGRYC--LGRRA---KYQSCHTEEC 580
>gi|110611170 ADAM metallopeptidase with thrombospondin type 1
motif, 17 preproprotein [Homo sapiens]
Length = 1095
Score = 37.7 bits (86), Expect = 0.010
Identities = 28/85 (32%), Positives = 34/85 (40%), Gaps = 10/85 (11%)
Query: 50 CFCDQACRFTGDCCFDYDRACPARPCFVGEWSPW---SGCADQCKPTTRVRRRSVQQEPQ 106
C D+ CR G+C P G+WSPW S C+ C R R+R P
Sbjct: 521 CGADKWCR-AGECV----SKTPIPEHVDGDWSPWGAWSMCSRTCGTGARFRQRKCDNPPP 575
Query: 107 N-GGAPCPPLE-ERAGCLEYSTPQG 129
GG CP E A C P+G
Sbjct: 576 GPGGTHCPGASVEHAVCENLPCPKG 600
>gi|145699139 cartilage intermediate layer protein 2 [Homo sapiens]
Length = 1156
Score = 37.7 bits (86), Expect = 0.010
Identities = 20/49 (40%), Positives = 23/49 (46%), Gaps = 6/49 (12%)
Query: 70 CPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCP--PLE 116
CP + G W PW C+ C P R+RRR P G CP PLE
Sbjct: 143 CPLEASW-GAWGPWGPCSGSCGPGRRLRRRHC---PSPAGDACPGRPLE 187
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 36.6 bits (83), Expect = 0.023
Identities = 36/107 (33%), Positives = 40/107 (37%), Gaps = 24/107 (22%)
Query: 22 CAEAGRCCPGRDPACFARGWRLDRVYGTCFCDQACRFTGDCCFDYDRACPARPCFVGEWS 81
CAE C P D CF G C C+ FTGD C D R CP
Sbjct: 315 CAETCDCAP--DARCFPAN-------GACLCEHG--FTGDRCTD--RLCP---------D 352
Query: 82 PWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAGCLEYSTPQ 128
+ G + Q P T R S+ P NG C P C E S PQ
Sbjct: 353 GFYGLSCQA-PCTCDREHSLSCHPMNGECSCLPGWAGLHCNE-SCPQ 397
>gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]
Length = 888
Score = 36.2 bits (82), Expect = 0.030
Identities = 19/68 (27%), Positives = 24/68 (35%), Gaps = 10/68 (14%)
Query: 22 CAEAGRCCPGRDPACF--ARGWRLDR--------VYGTCFCDQACRFTGDCCFDYDRACP 71
C CC D C ARGW + C C + C GDCC +Y C
Sbjct: 80 CKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCK 139
Query: 72 ARPCFVGE 79
+V +
Sbjct: 140 GESHWVDD 147
Score = 29.6 bits (65), Expect = 2.8
Identities = 9/21 (42%), Positives = 11/21 (52%)
Query: 50 CFCDQACRFTGDCCFDYDRAC 70
C CD C+ CC D+D C
Sbjct: 74 CRCDNLCKSYTSCCHDFDELC 94
>gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens]
Length = 863
Score = 36.2 bits (82), Expect = 0.030
Identities = 19/68 (27%), Positives = 24/68 (35%), Gaps = 10/68 (14%)
Query: 22 CAEAGRCCPGRDPACF--ARGWRLDR--------VYGTCFCDQACRFTGDCCFDYDRACP 71
C CC D C ARGW + C C + C GDCC +Y C
Sbjct: 80 CKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCK 139
Query: 72 ARPCFVGE 79
+V +
Sbjct: 140 GESHWVDD 147
Score = 29.6 bits (65), Expect = 2.8
Identities = 9/21 (42%), Positives = 11/21 (52%)
Query: 50 CFCDQACRFTGDCCFDYDRAC 70
C CD C+ CC D+D C
Sbjct: 74 CRCDNLCKSYTSCCHDFDELC 94
>gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens]
Length = 915
Score = 36.2 bits (82), Expect = 0.030
Identities = 19/68 (27%), Positives = 24/68 (35%), Gaps = 10/68 (14%)
Query: 22 CAEAGRCCPGRDPACF--ARGWRLDR--------VYGTCFCDQACRFTGDCCFDYDRACP 71
C CC D C ARGW + C C + C GDCC +Y C
Sbjct: 80 CKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCK 139
Query: 72 ARPCFVGE 79
+V +
Sbjct: 140 GESHWVDD 147
Score = 29.6 bits (65), Expect = 2.8
Identities = 9/21 (42%), Positives = 11/21 (52%)
Query: 50 CFCDQACRFTGDCCFDYDRAC 70
C CD C+ CC D+D C
Sbjct: 74 CRCDNLCKSYTSCCHDFDELC 94
>gi|4505737 complement factor properdin precursor [Homo sapiens]
Length = 469
Score = 35.8 bits (81), Expect = 0.039
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 1/46 (2%)
Query: 68 RACPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCP 113
+ CP + G W PW C+ C TR RRR+ G CP
Sbjct: 131 QCCPEMGGWSG-WGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCP 175
>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
Length = 1170
Score = 35.8 bits (81), Expect = 0.039
Identities = 31/110 (28%), Positives = 40/110 (36%), Gaps = 24/110 (21%)
Query: 26 GRCCPGRDPACFAR-GWRLDRVYGTCF--CDQACRFTGDCCFDYDRACPA-----RPCFV 77
G CCP P+ A GW + +C C + G C + C R C +
Sbjct: 366 GECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHI 425
Query: 78 GE-------------WSPWSGCADQCKP--TTRVRRRSVQQEPQNGGAPC 112
E WSPWS C+ C TR+R + PQ G PC
Sbjct: 426 QECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCN-SPSPQMNGKPC 474
Score = 32.3 bits (72), Expect = 0.44
Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 5/62 (8%)
Query: 52 CDQACRFTGDCCFDYDRACPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQ-EPQNGGA 110
C+ R T C D ACP + G WSPW C+ C + R R PQ GG
Sbjct: 474 CEGEARETKACKKD---ACPINGGW-GPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGK 529
Query: 111 PC 112
C
Sbjct: 530 DC 531
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 35.8 bits (81), Expect = 0.039
Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Query: 80 WSPWSGCADQCKPTTRVRRRSVQQ-EPQNGGAPC--PPLE-ERAGCLEYSTPQGQDCGHT 135
W+ WS C+ C R R+R EP+ GG PC P LE + L C
Sbjct: 790 WTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPVDGVWSCWSP 849
Query: 136 YVPAFITTSAFNKERTRQATSP 157
+ T + RTR ++P
Sbjct: 850 WTKCSATCGGGHYMRTRSCSNP 871
Score = 35.4 bits (80), Expect = 0.051
Identities = 22/81 (27%), Positives = 29/81 (35%), Gaps = 11/81 (13%)
Query: 70 CPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGA----------PCPPLEERA 119
CP + G W PW C QC + RRR + P G PCP L++
Sbjct: 650 CPPHMFWTG-WGPWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTT 708
Query: 120 GCLEYSTPQGQDCGHTYVPAF 140
++ D G Y F
Sbjct: 709 PWTPWTPVNISDNGGHYEQRF 729
Score = 29.6 bits (65), Expect = 2.8
Identities = 13/34 (38%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 80 WSPWSGCADQCKPTTRVRRRSVQQ-EPQNGGAPC 112
W+ WS C+ C +VR+RS P++GG C
Sbjct: 601 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVC 634
Score = 28.9 bits (63), Expect = 4.8
Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 6/65 (9%)
Query: 70 CPARPCFVGE----WSPWSGCADQCKPTTRVRRRSVQQ-EPQNGGAPCPPLE-ERAGCLE 123
C PC V WSPW+ C+ C +R RS P GG C L E A C
Sbjct: 833 CNILPCPVDGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNT 892
Query: 124 YSTPQ 128
P+
Sbjct: 893 QPCPE 897
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.501
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,793,531
Number of Sequences: 37866
Number of extensions: 640910
Number of successful extensions: 2535
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 2290
Number of HSP's gapped (non-prelim): 256
length of query: 264
length of database: 18,247,518
effective HSP length: 100
effective length of query: 164
effective length of database: 14,460,918
effective search space: 2371590552
effective search space used: 2371590552
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.