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Search of human proteins with 207452735
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|207452735 epiplakin 1 [Homo sapiens]
(5090 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|207452735 epiplakin 1 [Homo sapiens] 9895 0.0
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 1268 0.0
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 1268 0.0
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 1268 0.0
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 1268 0.0
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 1268 0.0
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 1268 0.0
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 1268 0.0
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 1268 0.0
gi|58530842 desmoplakin isoform II [Homo sapiens] 382 e-105
gi|58530840 desmoplakin isoform I [Homo sapiens] 382 e-105
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 261 1e-68
gi|33188443 microfilament and actin filament cross-linker protei... 127 2e-28
gi|156104874 envoplakin [Homo sapiens] 126 6e-28
gi|20357504 dystonin isoform 1eB precursor [Homo sapiens] 92 1e-17
gi|239749439 PREDICTED: similar to transcription factor 23 [Homo... 44 0.004
gi|239743573 PREDICTED: similar to transcription factor 23 [Homo... 44 0.004
gi|239754900 PREDICTED: similar to transcription factor 23 [Homo... 41 0.027
gi|239754110 PREDICTED: hypothetical protein XP_002345881 [Homo ... 40 0.077
gi|239748639 PREDICTED: hypothetical protein XP_002346752 [Homo ... 39 0.13
gi|30794216 tripartite motif-containing 56 [Homo sapiens] 39 0.13
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 39 0.17
gi|71274186 hypothetical protein LOC85449 [Homo sapiens] 39 0.17
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 37 0.50
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 37 0.66
gi|55749708 outer dense fiber of sperm tails 2-like isoform b [H... 37 0.66
gi|55749696 outer dense fiber of sperm tails 2-like isoform a [H... 37 0.66
gi|222537747 hypothetical protein LOC342979 [Homo sapiens] 36 0.86
gi|169214874 PREDICTED: hypothetical protein [Homo sapiens] 36 0.86
gi|169215109 PREDICTED: hypothetical protein [Homo sapiens] 36 0.86
>gi|207452735 epiplakin 1 [Homo sapiens]
Length = 5090
Score = 9895 bits (25677), Expect = 0.0
Identities = 5090/5090 (100%), Positives = 5090/5090 (100%)
Query: 1 MSGHTLPPLPVPGTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAA 60
MSGHTLPPLPVPGTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAA
Sbjct: 1 MSGHTLPPLPVPGTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAA 60
Query: 61 MEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATT 120
MEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATT
Sbjct: 61 MEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATT 120
Query: 121 GYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLL 180
GYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLL
Sbjct: 121 GYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLL 180
Query: 181 DRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALLPLKITFRSMGG 240
DRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALLPLKITFRSMGG
Sbjct: 181 DRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALLPLKITFRSMGG 240
Query: 241 AVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLLPEGHKKS 300
AVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLLPEGHKKS
Sbjct: 241 AVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLLPEGHKKS 300
Query: 301 FFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELHEQLLVAE 360
FFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELHEQLLVAE
Sbjct: 301 FFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELHEQLLVAE 360
Query: 361 QAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALR 420
QAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALR
Sbjct: 361 QAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALR 420
Query: 421 CGCLDEDTQRQLSQAGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGP 480
CGCLDEDTQRQLSQAGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGP
Sbjct: 421 CGCLDEDTQRQLSQAGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGP 480
Query: 481 PFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEK 540
PFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEK
Sbjct: 481 PFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEK 540
Query: 541 LAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLA 600
LAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLA
Sbjct: 541 LAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLA 600
Query: 601 SAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANK 660
SAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANK
Sbjct: 601 SAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANK 660
Query: 661 GHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLL 720
GHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLL
Sbjct: 661 GHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLL 720
Query: 721 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQ 780
EAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQ
Sbjct: 721 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQ 780
Query: 781 LLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSE 840
LLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSE
Sbjct: 781 LLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSE 840
Query: 841 YFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQ 900
YFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQ
Sbjct: 841 YFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQ 900
Query: 901 QLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVA 960
QLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVA
Sbjct: 901 QLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVA 960
Query: 961 LALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQV 1020
LALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQV
Sbjct: 961 LALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQV 1020
Query: 1021 SVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSS 1080
SVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSS
Sbjct: 1021 SVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSS 1080
Query: 1081 SETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKD 1140
SETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKD
Sbjct: 1081 SETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKD 1140
Query: 1141 GTSLWDLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPR 1200
GTSLWDLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPR
Sbjct: 1141 GTSLWDLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPR 1200
Query: 1201 GEVPAVWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKA 1260
GEVPAVWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKA
Sbjct: 1201 GEVPAVWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKA 1260
Query: 1261 SIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQA 1320
SIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQA
Sbjct: 1261 SIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQA 1320
Query: 1321 ERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAAC 1380
ERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAAC
Sbjct: 1321 ERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAAC 1380
Query: 1381 RLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVL 1440
RLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVL
Sbjct: 1381 RLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVL 1440
Query: 1441 EVDDHTAVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQ 1500
EVDDHTAVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQ
Sbjct: 1441 EVDDHTAVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQ 1500
Query: 1501 VVSAVTALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEM 1560
VVSAVTALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEM
Sbjct: 1501 VVSAVTALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEM 1560
Query: 1561 DSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAEN 1620
DSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAEN
Sbjct: 1561 DSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAEN 1620
Query: 1621 RKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRL 1680
RKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRL
Sbjct: 1621 RKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRL 1680
Query: 1681 LEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYL 1740
LEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYL
Sbjct: 1681 LEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYL 1740
Query: 1741 QLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLL 1800
QLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLL
Sbjct: 1741 QLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLL 1800
Query: 1801 SSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLF 1860
SSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLF
Sbjct: 1801 SSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLF 1860
Query: 1861 NSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKE 1920
NSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKE
Sbjct: 1861 NSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKE 1920
Query: 1921 LIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRD 1980
LIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRD
Sbjct: 1921 LIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRD 1980
Query: 1981 PATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDI 2040
PATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDI
Sbjct: 1981 PATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDI 2040
Query: 2041 YALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDETR 2100
YALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDETR
Sbjct: 2041 YALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDETR 2100
Query: 2101 RALEAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILE 2160
RALEAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILE
Sbjct: 2101 RALEAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILE 2160
Query: 2161 LIEKQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYL 2220
LIEKQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYL
Sbjct: 2161 LIEKQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYL 2220
Query: 2221 EGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLR 2280
EGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLR
Sbjct: 2221 EGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLR 2280
Query: 2281 LSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLE 2340
LSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLE
Sbjct: 2281 LSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLE 2340
Query: 2341 AQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQL 2400
AQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQL
Sbjct: 2341 AQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQL 2400
Query: 2401 LRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFY 2460
LRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFY
Sbjct: 2401 LRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFY 2460
Query: 2461 REVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAA 2520
REVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAA
Sbjct: 2461 REVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAA 2520
Query: 2521 TMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEE 2580
TMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEE
Sbjct: 2521 TMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEE 2580
Query: 2581 APGARPQLQDARRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRD 2640
APGARPQLQDARRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRD
Sbjct: 2581 APGARPQLQDARRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRD 2640
Query: 2641 ATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE 2700
ATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE
Sbjct: 2641 ATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE 2700
Query: 2701 ERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCI 2760
ERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCI
Sbjct: 2701 ERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCI 2760
Query: 2761 AGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEA 2820
AGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEA
Sbjct: 2761 AGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEA 2820
Query: 2821 VAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 2880
VAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG
Sbjct: 2821 VAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 2880
Query: 2881 GVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVP 2940
GVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVP
Sbjct: 2881 GVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVP 2940
Query: 2941 DPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSED 3000
DPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSED
Sbjct: 2941 DPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSED 3000
Query: 3001 RRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKV 3060
RRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKV
Sbjct: 3001 RRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKV 3060
Query: 3061 GRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARP 3120
GRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARP
Sbjct: 3061 GRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARP 3120
Query: 3121 QLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQ 3180
QLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQ
Sbjct: 3121 QLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQ 3180
Query: 3181 RGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV 3240
RGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV
Sbjct: 3181 RGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV 3240
Query: 3241 SFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVP 3300
SFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVP
Sbjct: 3241 SFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVP 3300
Query: 3301 AKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVV 3360
AKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVV
Sbjct: 3301 AKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVV 3360
Query: 3361 GGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPV 3420
GGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPV
Sbjct: 3361 GGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPV 3420
Query: 3421 HSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGL 3480
HSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGL
Sbjct: 3421 HSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGL 3480
Query: 3481 YMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLL 3540
YMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLL
Sbjct: 3481 YMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLL 3540
Query: 3541 SRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGR 3600
SRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGR
Sbjct: 3541 SRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGR 3600
Query: 3601 AVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAW 3660
AVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAW
Sbjct: 3601 AVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAW 3660
Query: 3661 RGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG 3720
RGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG
Sbjct: 3661 RGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG 3720
Query: 3721 RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 3780
RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR
Sbjct: 3721 RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 3780
Query: 3781 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 3840
RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG
Sbjct: 3781 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 3840
Query: 3841 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 3900
RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE
Sbjct: 3841 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 3900
Query: 3901 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 3960
KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 3901 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 3960
Query: 3961 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLA 4020
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLA
Sbjct: 3961 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLA 4020
Query: 4021 GRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAS 4080
GRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAS
Sbjct: 4021 GRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAS 4080
Query: 4081 TLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWD 4140
TLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWD
Sbjct: 4081 TLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWD 4140
Query: 4141 VLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREP 4200
VLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREP
Sbjct: 4141 VLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREP 4200
Query: 4201 GPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQTLRDATMEVQRGQFQGRPVSVW 4260
GPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQTLRDATMEVQRGQFQGRPVSVW
Sbjct: 4201 GPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQTLRDATMEVQRGQFQGRPVSVW 4260
Query: 4261 DVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSAS 4320
DVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSAS
Sbjct: 4261 DVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSAS 4320
Query: 4321 ELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMS 4380
ELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMS
Sbjct: 4321 ELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMS 4380
Query: 4381 IYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAE 4440
IYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAE
Sbjct: 4381 IYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAE 4440
Query: 4441 RAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR 4500
RAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR
Sbjct: 4441 RAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR 4500
Query: 4501 RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAV 4560
RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAV
Sbjct: 4501 RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAV 4560
Query: 4561 HQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEE 4620
HQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEE
Sbjct: 4561 HQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEE 4620
Query: 4621 LGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGY 4680
LGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGY
Sbjct: 4621 LGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGY 4680
Query: 4681 VSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRG 4740
VSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRG
Sbjct: 4681 VSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRG 4740
Query: 4741 DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSS 4800
DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSS
Sbjct: 4741 DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSS 4800
Query: 4801 YLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSASELHTSG 4860
YLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSASELHTSG
Sbjct: 4801 YLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSASELHTSG 4860
Query: 4861 ILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMW 4920
ILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMW
Sbjct: 4861 ILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMW 4920
Query: 4921 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4980
KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY
Sbjct: 4921 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4980
Query: 4981 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDE 5040
TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDE
Sbjct: 4981 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDE 5040
Query: 5041 EMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSLQ 5090
EMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSLQ
Sbjct: 5041 EMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSLQ 5090
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 1268 bits (3280), Expect = 0.0
Identities = 798/1967 (40%), Positives = 1134/1967 (57%), Gaps = 218/1967 (11%)
Query: 1511 AAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLEGG 1570
AAE +P + +F GLR++VSA+ L A ++S + L L+QG TTV E+A + V+ L+G
Sbjct: 2637 AAEAEP-EHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGR 2695
Query: 1571 NFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFK 1630
+ IAG+L++ T E++S+ AL+R +L PGTAL+LLEAQAA+GF++DP NR+LTV EA K
Sbjct: 2696 SSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVK 2755
Query: 1631 AGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGI 1690
G+ G E + KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGG+
Sbjct: 2756 EGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGV 2815
Query: 1691 IDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 1750
IDPVHSHRVPVDVAYR GYFDEEMNR+LADPSDDTKGFFDPNTHENLTYLQLLERCVEDP
Sbjct: 2816 IDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 2875
Query: 1751 ETGLYLLQI---IKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTE 1807
ETGL LL + KG VY + R V + T G+F + V+ W++++S YFT
Sbjct: 2876 ETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTA 2935
Query: 1808 DRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLFNSRVIDQ 1867
+++R+L++++ +EK+++II T +EE E Q + +R V AA+L SRVID+
Sbjct: 2936 EQRRDLLRQFRTGRITVEKIIKIIITVVEEQE-QKGRLCFEGLRSLVPAAELLESRVIDR 2994
Query: 1868 KTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFA 1927
+ L+ G + ++ ++ V+ L G++ IAGV + + +S++ A +K+L+P+ A
Sbjct: 2995 ELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMA 3054
Query: 1928 TWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTI 1987
LLEAQA TG ++DP T +L+VDEAV GLV E E+LL AE+A TGYRDP TG ++
Sbjct: 3055 VALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSV 3114
Query: 1988 PLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQ 2047
LFQA++K LI + + LRLL+ Q++TGG++DP HR+PL+ A RGCL ++ +S
Sbjct: 3115 SLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAP 3174
Query: 2048 KHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVN-KAAR---DSEHIDDETRRAL 2103
+ K + DP+T E +Y ELQ+RCRP + TG L P++ KAAR + + + + R
Sbjct: 3175 RADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETF 3234
Query: 2104 EAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIE 2163
E VE+ VG F+G+ T+W L++SEY T E++ +L+R +RT + ++ V ++++ ++E
Sbjct: 3235 EKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRT-GKVTVEKVIKILITIVE 3293
Query: 2164 KQET-SNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEG 2222
+ ET + L F G+R + ASELL+S +++ + L+ G++T ++L E V+ L+G
Sbjct: 3294 EVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQG 3353
Query: 2223 TSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLS 2282
+ C+AG+ + +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL
Sbjct: 3354 SGCLAGIYL-----EDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLY 3408
Query: 2283 VEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQ 2342
V E V AGVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQ
Sbjct: 3409 VHEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQ 3468
Query: 2343 IATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLR 2402
IATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL
Sbjct: 3469 IATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLE 3528
Query: 2403 RCVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVW 2455
RCV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+W
Sbjct: 3529 RCVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLW 3588
Query: 2456 ELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAE 2503
E++ + E++R L++ ++AG +T E + + ++ + + + R
Sbjct: 3589 EVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLT 3648
Query: 2504 A----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWD 2538
A EA + LR T ++ G + G +P ++
Sbjct: 3649 AEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQ 3708
Query: 2539 VLASGYVS-RAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDARRGPRE 2597
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3709 ALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER 3766
Query: 2598 PGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSV 2657
A G D Q + +E A R + L + R F P+ V
Sbjct: 3767 ---AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV 3822
Query: 2658 WDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS------------- 2704
YL++ D+ L + V + V T+ERLS
Sbjct: 3823 --AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDG 3869
Query: 2705 ------------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKR 2752
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ ++++
Sbjct: 3870 TGQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQK 3927
Query: 2753 YLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 2812
+LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++
Sbjct: 3928 FLEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKG 3982
Query: 2813 LRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRL 2872
L+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRL
Sbjct: 3983 LKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRL 4042
Query: 2873 LEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYV 2932
LEAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+
Sbjct: 4043 LEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYL 4102
Query: 2933 QLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELL 2992
QL+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4103 QLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE-- 4156
Query: 2993 FYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALR 3052
YR G + + T L Q E S
Sbjct: 4157 ---------------AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------D 4187
Query: 3053 AATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEA 3112
+ + R GR + D +A + +A L ++ +GTL + L+
Sbjct: 4188 GVVKSMIIDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS------ 4237
Query: 3113 EEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTL 3172
G++G + G + + A +R Q +
Sbjct: 4238 ---------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASW 4270
Query: 3173 RDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVA 3224
D T E G G VS+ + + + + LL AQ G +
Sbjct: 4271 SDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI------- 4321
Query: 3225 VLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQE 3277
+ T ER ++ +GL ++ ++ + G P T ++ +
Sbjct: 4322 ----IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKG 4377
Query: 3278 VTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 3337
++ +R+LE G++ P D PGR + + +A+ +G + TA L + A +
Sbjct: 4378 WLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYS 4432
Query: 3338 GFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3383
++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4433 KYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4479
Score = 1127 bits (2914), Expect = 0.0
Identities = 724/1911 (37%), Positives = 1065/1911 (55%), Gaps = 110/1911 (5%)
Query: 522 EQRAMLAQQYQEGTLSVEKL-AAELSAT---------LEQAAATARV--TFSGLRDTVTP 569
EQ +L +Q++ E++ A++++AT L+ AA A +F GLR V+
Sbjct: 2596 EQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSA 2655
Query: 570 GELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEA 629
L +A I+ + +RL G T ++ + YLQG IAGLLL + E+LS+Y A
Sbjct: 2656 QRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAA 2715
Query: 630 RCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVT 689
+ LL PGTALILLEAQAA+GF++DP N+ +V EA++ V+GP++ KLLSAERAVT
Sbjct: 2716 LQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVT 2775
Query: 690 GYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 749
GY DPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF
Sbjct: 2776 GYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 2835
Query: 750 DQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSP----- 804
D+ +N +L DPSDDTKGFFDPNTHENLTYLQLLERCV DPETGL LLPL+ +
Sbjct: 2836 DEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELV 2895
Query: 805 LVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQV 864
DS + F+ +S +G+FQG+ V+ WE+INSEYF+ +RR LLR++R +T+ ++
Sbjct: 2896 YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKI 2955
Query: 865 AKLLEA---ETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDG 921
K++ E +++ + LRS V +LLE+ +ID++L Q+ G S + +D
Sbjct: 2956 IKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDT 3015
Query: 922 VRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPES 981
VRR L G + GV L +GQ+LS+Y A+++ LL +A+ALLEAQA TG I+DP +
Sbjct: 3016 VRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSAR 3075
Query: 982 LSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLE 1041
L+VDEAVR G+VGPE + +L AE A+ G+RDP++G+ VS+FQA+KKGLIP EQ RLL+
Sbjct: 3076 LTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLD 3135
Query: 1042 AQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSS---SSETFPTPDGQGRTSYAQL 1098
AQ++TGGI+DP+ H +P+ VA RG +D+E ALS+ ++ + P +Y +L
Sbjct: 3136 AQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGEL 3195
Query: 1099 LEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQA------------VPGAKDGT-SLW 1145
+ C D+ +GL LLPL E A A +E++ LQA V G K T ++W
Sbjct: 3196 QQRCRPDQLTGLSLLPLSEKA-ARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVW 3254
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+SS +FT EQR+ LL + G+ TV +++ + V+E + L Q R+ G R VPA
Sbjct: 3255 ELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPA 3314
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQA 1265
LL +G++++ E L G + ++E +V+ L G+GC+AG+ L+ + K SI +A
Sbjct: 3315 SELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEA 3374
Query: 1266 VRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAA 1325
+R GLL LLEAQ A+GFLVDP+ NQRL V +AVK G+VG EL EQL AE+A
Sbjct: 3375 MRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVT 3434
Query: 1326 GYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLL 1385
GY DPYS +++SL+QAM+KGLV + G+ LL+ Q+ATGG++DPVH +P A + G
Sbjct: 3435 GYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYF 3494
Query: 1386 DTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDH 1445
+ ++VL D K FFDP+ + +TY+QL ERCV D ETGL LLPL EV +
Sbjct: 3495 SEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVET 3554
Query: 1446 TAV--------ALRAMKVPV-STGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAA 1496
T V A ++ + G G ++SLW+++ S+ + ++R +L+A ++GR
Sbjct: 3555 TQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVT 3614
Query: 1497 ALRQVVSAVTALVEAAE--RQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTV 1554
R ++ + ++E E RQ A++ +R++++A DLF A++IS +T + L +GT ++
Sbjct: 3615 KERMII-IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSL 3673
Query: 1555 KEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFI 1614
+E E +S L G +AGV + G+++ +SI +AL++ +L A +LLEAQAATGF+
Sbjct: 3674 REALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFL 3733
Query: 1615 IDPAENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 1674
+DP + +LTV+EA + G+ G E + +LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3734 LDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPT 3793
Query: 1675 EHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTH 1734
E +RLL+AQ+ATGGI+DP +P++VAY+ GY +++ + L++PS+ + + DP+T
Sbjct: 3794 EEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSE-VRSYVDPSTD 3852
Query: 1735 ENLTYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVV 1794
E L+Y QLL RC D TG LL + A+ R + +
Sbjct: 3853 ERLSYTQLLRRCRRDDGTGQLLLPL--------------------SDARKLTFRGLRKQI 3892
Query: 1795 SFWDLLSSPYFTED---RKRELIQEYGAQSGGLEKLLE-------IITTTIEETETQNQG 1844
+ +L+ S E + RE + + L+K LE + +E + Q
Sbjct: 3893 TMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQA 3952
Query: 1845 IKVAAIRG----EVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIA 1900
+K IR E+ A VID L V + E L +
Sbjct: 3953 MKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVT 4012
Query: 1901 GVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLV 1960
G P + +++SL +A +K LI LLEAQ ATG ++DP +L V+ A GL
Sbjct: 4013 GYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLF 4072
Query: 1961 NEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLL------------- 2007
+EE+ E L G+ DP T + + Q M++ + + L LL
Sbjct: 4073 DEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSS 4132
Query: 2008 --EVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSY 2065
V+ ++DP+ + + AYR+G + Y +S+Q+ + ++ V
Sbjct: 4133 KSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKS 4192
Query: 2066 RELQERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALE----AEQVEITVGRFRGQKPT 2121
+ R Q D + + K D +D L A+ + G FR + +
Sbjct: 4193 MIIDRRSGRQYD---IDDAIAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSS 4249
Query: 2122 LWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQI 2181
+ + + + QL + T L E +EK S + + I
Sbjct: 4250 VGSSSSYPISPAVSRTQLA-SWSDPTEETGPVAGILDTETLEK--VSITEAMHRNLVDNI 4306
Query: 2182 TASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQE 2241
T LL + T ++ R + + V + + +A + P +
Sbjct: 4307 TGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKT 4366
Query: 2242 KMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLL 2301
KMS QA+ KG L LE Q TG +I+P R+ ++E + G V + +KL
Sbjct: 4367 KMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLR 4426
Query: 2302 SAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 2351
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4427 DVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4477
Score = 1054 bits (2725), Expect = 0.0
Identities = 630/1557 (40%), Positives = 924/1557 (59%), Gaps = 83/1557 (5%)
Query: 869 EAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCG 928
EAE + D LR +V+ +L EAGI+ + L ++ G + + L + VR YL G
Sbjct: 2639 EAEPEHSFD----GLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQG 2694
Query: 929 LGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAV 988
++ G+ L + ++LS+Y A++++LL P AL LLEAQAA+G ++DP L+V+EAV
Sbjct: 2695 RSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAV 2754
Query: 989 RRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGG 1048
+ GVVGPEL+ +L AE A+ G++DP++G+Q+S+FQAM+KGLI E RLLEAQ+ATGG
Sbjct: 2755 KEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGG 2814
Query: 1049 IIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRD 1105
+IDP H +P+ VA +RGY D+EM L+ S+ F P+ +Y QLLE C D
Sbjct: 2815 VIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVED 2874
Query: 1106 ETSGLHLLPLPESAPA--------LPTEEQVQRSLQAVPGAK---DGTSLWDLLSSCHFT 1154
+GL LLPL + A + +++ + P K ++W++++S +FT
Sbjct: 2875 PETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFT 2934
Query: 1155 EEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDAGII 1214
EQRR LL + GR TV +++ + V+E + + R+ G R VPA LL++ +I
Sbjct: 2935 AEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE--QKGRLCFEGLRSLVPAAELLESRVI 2992
Query: 1215 TQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTG 1274
+E + L +G +S VAE V+ L G +AGV L+ +G K SI A++ LLP+
Sbjct: 2993 DRELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSD 3052
Query: 1275 LGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRA 1334
+ LLEAQ +G ++DP + RL+V++AV+ GLVG E E+L AE+A GY DPY+
Sbjct: 3053 MAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQ 3112
Query: 1335 SLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLT 1394
S+SL+QA++KGL+P+ +GL LL QL+TGG+VDP +P AC G LD +TS+ L+
Sbjct: 3113 SVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALS 3172
Query: 1395 AVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMK 1454
A D K + DPS + TY +L++RC D TGL LLPL + L+A +
Sbjct: 3173 APRADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARE 3232
Query: 1455 ------VPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVTAL 1508
V V G FKG +V++W+L+ SEY A++R+EL+ R+G+ + + +T +
Sbjct: 3233 TFEKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIV 3292
Query: 1509 VEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
E + + +F GLR V A +L + ++SR ++L G TTVK+++E+ SV+ L+
Sbjct: 3293 EEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQ 3352
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G +AG+ ++ T+E++SI EA+RR +LR TA +LLEAQAATGF++DP N++L V EA
Sbjct: 3353 GSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEA 3412
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 1688
KAG+ G E + +LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATG
Sbjct: 3413 VKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATG 3472
Query: 1689 GIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVE 1748
GIIDPVHSHRVPVDVAY+ GYF EEMNR+LADPSDDTKGFFDPNTHENLTY QLLERCVE
Sbjct: 3473 GIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVE 3532
Query: 1749 DPETGLYLLQI--IKKGE----NYVYINEATRHVLQSRTAKM-RVGRFADQVVSFWDLLS 1801
DPETGL LL + +K E VY E TR + + G +S W+++
Sbjct: 3533 DPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQ 3592
Query: 1802 SPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETE-TQNQGI-KVAAIRGEVTAADL 1859
S E+++ +L+ ++ A E+++ II IE+TE + QG+ +R +TA DL
Sbjct: 3593 SDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDL 3652
Query: 1860 FNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRK 1919
F +R+I +T + LR G + E YL G+ +AGV +P +R+ +S+++A +K
Sbjct: 3653 FEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKK 3712
Query: 1920 ELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYR 1979
L+ A A LLEAQAATGFLLDP ++L+VDEAV GLV EL +RLL AERA TGYR
Sbjct: 3713 GLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYR 3772
Query: 1980 DPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKD 2039
DP T TI LFQAM+K+LI EALRLL+ Q+ATGG++DP+ LPLE AY+RG L+KD
Sbjct: 3773 DPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKD 3832
Query: 2040 IYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDET 2099
+ +S+ +R +VDP+T E++SY +L RCR + TG +L P++ A + +
Sbjct: 3833 THDQLSEPSEVRS-YVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT------- 3884
Query: 2100 RRALEAEQVEITVGRFRG--QKPTLWALLNSEYVTEEKKLQL------VRMYRTHTRRAL 2151
FRG ++ T+ L+ S+ + E LQL + + ++ L
Sbjct: 3885 ---------------FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFL 3929
Query: 2152 QTVAQLILELIE--KQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQE 2209
+ + + ++ K+ S +GI R TA ELL + T ++ ++ + T +E
Sbjct: 3930 EGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 3989
Query: 2210 LMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 2269
+ V + A V P + +S++QAM KG++ + LLEAQ AT
Sbjct: 3990 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4049
Query: 2270 GFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDL 2329
G +IDP + RL VE G+ E+ E L G+ DP T + ++ Q M++ +
Sbjct: 4050 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4109
Query: 2330 IVREHGIRLL-------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 2371
+ G+ LL E + ++ ++DP + V AYR+G D +
Sbjct: 4110 TDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4166
Score = 999 bits (2583), Expect = 0.0
Identities = 666/1843 (36%), Positives = 989/1843 (53%), Gaps = 126/1843 (6%)
Query: 234 TFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLL 293
+F + VSA L E GIL + +Q L +G +++ R +VR YL+G S+AG++L
Sbjct: 2645 SFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLK 2704
Query: 294 PEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELH 353
K S + A LL GTAL LLEAQAA+ L+DP+ +RL V+EAV+ G+V PELH
Sbjct: 2705 ATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELH 2764
Query: 354 EQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRL 413
+LL AE+AVTG+ DP++G QI LFQAM+KGL+ R +RLL+AQ+ATGG++ P R+
Sbjct: 2765 HKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRV 2824
Query: 414 PLEAALRCGCLDEDTQRQLSQA-----GSFSDGTHGGLRYEQLLALCVTDPETGLAFLPL 468
P++ A R G DE+ R L+ G F TH L Y QLL CV DPETGL LPL
Sbjct: 2825 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPL 2884
Query: 469 SG-GPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAML 527
+ +GGE + R AT + GKF+G+ V++WE++ SE ++EQR L
Sbjct: 2885 TDKAAKGGELV---YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDL 2941
Query: 528 AQQYQEGTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLE 587
+Q++ G ++VEK+ + +E+ R+ F GLR V ELL++ +ID++LY++L+
Sbjct: 2942 LRQFRTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQ 3001
Query: 588 HGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQ 647
G+ + +DV + + +R L+G IAG+ L + ++LSIY A K LL A+ LLEAQ
Sbjct: 3002 RGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQ 3061
Query: 648 AATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQ 707
A TG IIDP + +V+EA+RA ++GP+ KLLSAE+AVTGY DPYTGQ +SLFQA++
Sbjct: 3062 AGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALK 3121
Query: 708 KGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGF 767
KGLI RE G+RLL+AQ++TGG++DP SHRVP+DVA RG D+ + L P D K +
Sbjct: 3122 KGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAY 3181
Query: 768 FDPNTHENLTYLQLLERCVRDPETGLYLLPLS-----STQSPLV-DSATQQAFQNLLLSV 821
DP+T E TY +L +RC D TGL LLPLS + Q L + ++ F+ + V
Sbjct: 3182 SDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEV 3241
Query: 822 KYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQVAKLL-----EAETQRQA 876
G F+G+ V+ WELI+SEYF+ +R++LLR++R +VT+ +V K+L E ET RQ
Sbjct: 3242 PVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQE 3301
Query: 877 DIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVR 936
+ LR+ V +LL +G++ + +Q+ G + + L + VR L G G + G+
Sbjct: 3302 RLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIY 3361
Query: 937 LLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPE 996
L + +++S+Y+AMR+ LL A LLEAQAATG ++DP + L V EAV+ GVVGPE
Sbjct: 3362 LEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPE 3421
Query: 997 LYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHH 1056
L+ +L AE A+ G+RDP+SG +S+FQAM+KGL+ + RLLEAQ+ATGGIIDP H
Sbjct: 3422 LHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSH 3481
Query: 1057 HLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRDETSGLHLL 1113
+P+ VA QRGY +EM L+ S+ F P+ +Y QLLE C D +GL LL
Sbjct: 3482 RVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLL 3541
Query: 1114 PLPESAPA-------LPTEEQVQRSLQA----VPG----AKDGTSLWDLLSSCHFTEEQR 1158
PL + A + TEE+ +R+ + +PG SLW+++ S EEQR
Sbjct: 3542 PLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQR 3601
Query: 1159 RGLLEDVQEGRTTVPQLLASVQRWVQETKLL-AQARVMVPGPRGEVPAVWLLDAGIITQE 1217
L+ D Q GR T +++ + +++T+++ Q R + A L +A II+ E
Sbjct: 3602 AQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLE 3661
Query: 1218 TLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQ 1277
T L +GT+S + E + L+GTG VAGV L S SI QA++ GLL + +
Sbjct: 3662 TYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVAR 3721
Query: 1278 RLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLS 1337
LLEAQ A+GFL+DP+ +RL+V++AV+ GLVG EL ++L AERA GY DPY+ ++S
Sbjct: 3722 LLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTIS 3781
Query: 1338 LWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVD 1397
L+QAM+K L+P E L LL QLATGG+VDP G HLP A + G L+ T L+
Sbjct: 3782 LFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSE-P 3840
Query: 1398 KDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPV 1457
+ + + DPS ++++Y QL RC D TG LLLPL D + R ++ +
Sbjct: 3841 SEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPL--------SDARKLTFRGLRKQI 3892
Query: 1458 STGRFKGCSVSLWDLLLSEYVGADKRRELVALCR-SGRAAALRQVVSAVTALVEAAERQP 1516
+ V + E R L ++ + + S + + A ++
Sbjct: 3893 TMEELVRSQV------MDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKER 3946
Query: 1517 L---QATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSV-----KRSLE 1568
L QA +G+ + +A +L AQ + +D + TV+E M V + L
Sbjct: 3947 LSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLS 4006
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
+ G + + +S+ +A+++ ++ + LLEAQ ATG IIDP E+ +L VE A
Sbjct: 4007 AERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVA 4066
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL------- 1681
+K G+F +E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4067 YKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKR 4126
Query: 1682 EAQIATGG--------IIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNT 1733
E + ++ I+DP + V AYR G D +
Sbjct: 4127 ERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ-------------------- 4166
Query: 1734 HENLTYLQLLERCVEDPE------TGLYLLQIIKKGENYVY-INEATRHVLQSRTAKMRV 1786
TYL+L E+ E E G+ II + Y I++A L R+A +
Sbjct: 4167 ----TYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRSALDQY 4222
Query: 1787 GRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIK 1846
+ F D+LS R G+ S T ++ +
Sbjct: 4223 RAGTLSITEFADMLSG---NAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGP 4279
Query: 1847 VAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPS 1906
VA I T +V + +H V GQ L LE C G+ PS
Sbjct: 4280 VAGILDTETL-----EKVSITEAMHRNLVDNITGQRL---------LEAQACTGGIIDPS 4325
Query: 1907 TREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRE 1966
T E + +A K L+ + AQ A DP T+ K+S +A+ G + E +
Sbjct: 4326 TGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQ 4385
Query: 1967 RLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEV 2009
R L+ + G +P T +PL +A+Q+ ++ A +L +V
Sbjct: 4386 RFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV 4428
Score = 970 bits (2508), Expect = 0.0
Identities = 547/1287 (42%), Positives = 810/1287 (62%), Gaps = 33/1287 (2%)
Query: 1155 EEQRRGLL---EDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDA 1211
EEQ R L E+V + + L + + + A+ G R +V A L +A
Sbjct: 2602 EEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEA 2661
Query: 1212 GIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLL 1271
GI++ E L+ LAQG + ++A + V+ L G +AG+LL+ + K S+ A++ LL
Sbjct: 2662 GILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLL 2721
Query: 1272 PTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPY 1331
G LLEAQ ASGFL+DP+ N+RL+V +AVK G+VG EL +L AERA GY DPY
Sbjct: 2722 SPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPY 2781
Query: 1332 SRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQ 1391
+ +SL+QAM+KGL+ + G+ LL+ Q+ATGGV+DPVH +P A R G D + ++
Sbjct: 2782 TGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNR 2841
Query: 1392 VLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDT-----VLEVDDHT 1446
VL D K FFDP+ + +TY QL ERCV D ETGL LLPL ++ D
Sbjct: 2842 VLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEA 2901
Query: 1447 AVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVT 1506
V G+F+G +V++W+++ SEY A++RR+L+ R+GR + +++ +
Sbjct: 2902 RDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRIT-VEKIIKIII 2960
Query: 1507 ALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRS 1566
+VE E++ + F GLR V A +L +++I R+ +L +G +V++VAE+D+V+R+
Sbjct: 2961 TVVEEQEQKG-RLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 3019
Query: 1567 LEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVE 1626
L G N IAGV ++ +++SI AL++ +L A+ LLEAQA TG IIDPA + +LTV+
Sbjct: 3020 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVD 3079
Query: 1627 EAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIA 1686
EA +AG+ G E + KLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++
Sbjct: 3080 EAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLS 3139
Query: 1687 TGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERC 1746
TGGI+DP SHRVP+DVA G DEE +R L+ P D K + DP+T E TY +L +RC
Sbjct: 3140 TGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRC 3199
Query: 1747 VEDPETGLYLLQIIKKG----ENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSS 1802
D TGL LL + +K + +Y R + ++ VG F + V+ W+L+SS
Sbjct: 3200 RPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3259
Query: 1803 PYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQG-IKVAAIRGEVTAADLFN 1861
YFT ++++EL++++ +EK+++I+ T +EE ET Q + + +R V A++L
Sbjct: 3260 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3319
Query: 1862 SRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKEL 1921
S V+ + L+ G+T + LS L V+ L+GS C+AG+ + T+E +S++EA R+ L
Sbjct: 3320 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3379
Query: 1922 IPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDP 1981
+ A A LLEAQAATGFL+DP Q+L V EAV G+V EL E+LL AE+A TGYRDP
Sbjct: 3380 LRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDP 3439
Query: 1982 ATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIY 2041
+G TI LFQAMQK L+ + +RLLE Q+ATGG+IDP H HR+P++ AY+RG +++
Sbjct: 3440 YSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMN 3499
Query: 2042 ALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSE-------H 2094
+++D K F DPNT E ++YR+L ERC +TG L P+ K A +E +
Sbjct: 3500 RVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL-KGAEKAEVVETTQVY 3558
Query: 2095 IDDETRRALEAEQVEITVGRFRGQKP-TLWALLNSEYVTEEKKLQLVRMYRTHTRRALQT 2153
++ETRRA E Q++I G G +LW ++ S+ + EE++ QL+ ++ R +
Sbjct: 3559 TEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAG-RVTKER 3617
Query: 2154 VAQLILELIEKQETSNKH--LWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELM 2211
+ +I+E+IEK E + + +RR++TA +L + II+ E L G + +E +
Sbjct: 3618 MIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREAL 3677
Query: 2212 EDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGF 2271
E + YL GT +AGV +P G ++ +SIYQA+ KG+L A +LLEAQAATGF
Sbjct: 3678 EAESAWCYLYGTGSVAGVYLP-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGF 3732
Query: 2272 VIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIV 2331
++DPV+ RL+V+E V G+VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3733 LLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIP 3792
Query: 2332 REHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNT 2391
E +RLL+AQ+ATGG++DP +P++VAY+RGY +++ + L++PS + + + DP+T
Sbjct: 3793 TEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPST 3851
Query: 2392 HENLTYVQLLRRCVPDPDTGLYMLQLA 2418
E L+Y QLLRRC D TG +L L+
Sbjct: 3852 DERLSYTQLLRRCRRDDGTGQLLLPLS 3878
Score = 881 bits (2277), Expect = 0.0
Identities = 629/1746 (36%), Positives = 913/1746 (52%), Gaps = 133/1746 (7%)
Query: 41 RSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQ 100
R++ G +GQ S++ AM++GL+ G LLEAQ ATGG++D +PV A +
Sbjct: 2772 RAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR 2831
Query: 101 QGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEV--QLATG 158
+G E+ L T G+ DP E L Q + + V D G L + + A G
Sbjct: 2832 RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKG 2891
Query: 159 GLV----DPAQGVLVAPEPACHQGLLDRET---WHKLSELEPGTGDLR--FLNPNTLERL 209
G + A+ V + G +T W ++ E T + R L R+
Sbjct: 2892 GELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINS-EYFTAEQRRDLLRQFRTGRI 2950
Query: 210 TYHQLLERCVRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAV 269
T ++++ + ++ F + V AAELLE ++D + Q L+ G +
Sbjct: 2951 TVEKIIKIIITVVEEQEQ--KGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVR 3008
Query: 270 DVSARAEVRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLV 329
DV+ VRR L G +AGV L G K S + A + LLP A+ LLEAQA T ++
Sbjct: 3009 DVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHII 3068
Query: 330 DPITGQRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRP 389
DP T RL VDEAVRAGLV PE HE+LL AE+AVTG+ DP++G + LFQA+KKGL+ R
Sbjct: 3069 DPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPRE 3128
Query: 390 LALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLS----QAGSFSDGTHGG 445
LRLLDAQL+TGG+V P++ R+PL+ A GCLDE+T R LS A ++SD + G
Sbjct: 3129 QGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGE 3188
Query: 446 -LRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFR 504
Y +L C D TGL+ LPLS Q + + R+ V VG F+
Sbjct: 3189 PATYGELQQRCRPDQLTGLSLLPLSEKAARAR-QEELYSELQARETFEKTPVEVPVGGFK 3247
Query: 505 GRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAELSATLEQAAATA--RVTFSG 562
GR V++WEL+ SE ++EQR L +Q++ G ++VEK+ L +E+ R++FSG
Sbjct: 3248 GRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSG 3307
Query: 563 LRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQE 622
LR V ELL + ++ + +E+L+ G+ T KD+ L S + LQG+GC+AG+ L ++E
Sbjct: 3308 LRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKE 3367
Query: 623 RLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLL 682
++SIYEA +GLLR TA +LLEAQAATGF++DP N+ V EA++A V+GP++ +LL
Sbjct: 3368 KVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLL 3427
Query: 683 SAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDV 742
SAE+AVTGY DPY+G ISLFQAMQKGL++R+HGIRLLEAQIATGG+IDPVHSHRVPVDV
Sbjct: 3428 SAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3487
Query: 743 AYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQ 802
AY+RGYF + +N +L DPSDDTKGFFDPNTHENLTY QLLERCV DPETGL LLPL +
Sbjct: 3488 AYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAE 3547
Query: 803 SPLV--------DSATQQAFQNLLLSVK-YGRFQGQRVSAWELINSEYFSEGRRRQLLRR 853
V + T++AF+ + + G G +S WE++ S+ E +R QL+
Sbjct: 3548 KAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMAD 3607
Query: 854 YRQREVTLGQVAKLL-----EAETQRQADI-MLPALRSRVTVHQLLEAGIIDQQLLDQVL 907
++ VT ++ ++ + E RQ + +R R+T L EA II + + +
Sbjct: 3608 FQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLR 3667
Query: 908 AGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQ 967
GT S L + YL G G+V GV L S Q LS+YQA+++ LL VA LLEAQ
Sbjct: 3668 EGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQ 3727
Query: 968 AATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMK 1027
AATG ++DP E L+VDEAVR+G+VGPEL+ RL AE A+ G+RDP++ + +S+FQAMK
Sbjct: 3728 AATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMK 3787
Query: 1028 KGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSE--TFP 1085
K LIP E+A RLL+AQ+ATGGI+DP HLP+ VA QRGY++++ LS SE ++
Sbjct: 3788 KELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYV 3847
Query: 1086 TPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGTSLW 1145
P R SY QLL C RD+ +G LLPL ++ R L G + ++
Sbjct: 3848 DPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDA-----------RKL-TFRGLRKQITME 3895
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+ S E L +EG T++ ++ ++Q++++ T + A V V + +
Sbjct: 3896 ELVRSQVMDEATALQL----REGLTSIEEVTKNLQKFLEGTSCI--AGVFVDATKERLSV 3949
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAE---------QPAVKACLWG----------TG 1246
+ GII T L + + V + + AV+ + G
Sbjct: 3950 YQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAER 4009
Query: 1247 CVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKV 1306
V G SG S+ QA++ GL+ G RLLEAQ+A+G ++DP + RL VE A K
Sbjct: 4010 AVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKR 4069
Query: 1307 GLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLL---------- 1356
GL E++E L G+ DP + +L+ Q ME+ + GL LL
Sbjct: 4070 GLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERK 4129
Query: 1357 -----QVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQ 1411
V+ +VDP G + A R GL+D QT L+ + + ++
Sbjct: 4130 TSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECE---------WEE 4180
Query: 1412 VTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLW- 1470
+T D +++ S ++DD A L + +++ ++S+
Sbjct: 4181 ITISS------SDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRS---ALDQYRAGTLSITE 4231
Query: 1471 --DLLLSEYVGADKRRELVALCRS---GRAAALRQVVS---------AVTALVEAAERQP 1516
D+L G R V S A + Q+ S V +++ +
Sbjct: 4232 FADMLSGNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEK 4291
Query: 1517 L---QATFRGLRKQVSARDLFRAQ-----LISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
+ +A R L ++ + L AQ +I T + K + + V R
Sbjct: 4292 VSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINL 4351
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G T+ +MS +AL++ L LE Q TG +I+P ++ ++EA
Sbjct: 4352 AQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEA 4411
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-AT 1687
+ G T KL T P T +IS A+ + ++ G+RLLEA +T
Sbjct: 4412 LQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4471
Query: 1688 GGIIDP 1693
G P
Sbjct: 4472 KGYYSP 4477
Score = 869 bits (2246), Expect = 0.0
Identities = 711/2089 (34%), Positives = 1014/2089 (48%), Gaps = 390/2089 (18%)
Query: 2610 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 2665
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2534 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2593
Query: 2666 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 2712
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2594 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2650
Query: 2713 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 2772
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2651 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2707
Query: 2773 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 2832
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2708 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2765
Query: 2833 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2892
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2766 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2825
Query: 2893 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL- 2951
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L
Sbjct: 2826 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2885
Query: 2952 --AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRY 3009
A +G + E R A V+ G QG++V++WE++ + ++R+DLL ++
Sbjct: 2886 DKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQF 2945
Query: 3010 RAGTLTVEELGATLTSLLAQAQAQAR----------AEAEAGSPRPDPREALR------- 3052
R G +TVE++ + +++ + + + R AE R RE +
Sbjct: 2946 RTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGER 3005
Query: 3053 ----AATMEVKVGRLRGRAV--PVWDVLASGYVS--GAAREELL----------AEFGSG 3094
A ++ LRG V VW A +S A +++LL A+ G+G
Sbjct: 3006 SVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTG 3065
Query: 3095 TLDLPALTRRLTAIIEEAEEAPGARPQL--------------QDAWRG------------ 3128
+ PA + RLT ++EA A P+ +D + G
Sbjct: 3066 HIIDPATSARLT--VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKG 3123
Query: 3129 --PREPG-------PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQ 3168
PRE G + G D +S R G + ET A +A A A
Sbjct: 3124 LIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSD 3183
Query: 3169 EQTLRDATM-EVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLT 3227
T AT E+Q+ + + + S + AR++EL ++ A
Sbjct: 3184 PSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------R 3231
Query: 3228 RVIEETEERLSKVSFRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV----- 3278
E+T + F+G R V+ EL +S E LR G T+++V
Sbjct: 3232 ETFEKTPVEVPVGGFKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILI 3289
Query: 3279 TEMDSVKRYLEGTSCIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALV 3329
T ++ V+ + +G+ VPA + + E++ + K + G+
Sbjct: 3290 TIVEEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRT 3349
Query: 3330 LLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP-------- 3381
LL+ + ++S+ EA+ G++ LL A+ A DP
Sbjct: 3350 LLQGSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYV 3409
Query: 3382 ------------------------------YTGQQISLFQAMQKDLIVREHGIRLLEAQI 3411
Y+G ISLFQAMQK L++R+HGIRLLEAQI
Sbjct: 3410 HEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQI 3469
Query: 3412 ATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRR 3471
ATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL R
Sbjct: 3470 ATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLER 3529
Query: 3472 CVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWE 3524
CV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+WE
Sbjct: 3530 CVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWE 3589
Query: 3525 LLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA 3572
++ + E++R L++ ++AG +T E + + ++ + + + R A
Sbjct: 3590 VMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTA 3649
Query: 3573 ----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDV 3607
EA + LR T ++ G + G +P ++
Sbjct: 3650 EDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQA 3709
Query: 3608 LASGYVSG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREP 3666
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3710 LKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER- 3766
Query: 3667 GPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVW 3726
A G D Q + +E A R + L + R F P+ V
Sbjct: 3767 --AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV- 3822
Query: 3727 DVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------- 3772
YL++ D+ L + V + V T+ERLS
Sbjct: 3823 -AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGT 3870
Query: 3773 -----------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 3821
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++
Sbjct: 3871 GQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKF 3928
Query: 3822 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 3881
LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L
Sbjct: 3929 LEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGL 3983
Query: 3882 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 3941
+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLL
Sbjct: 3984 KLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLL 4043
Query: 3942 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQ 4001
EAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+Q
Sbjct: 4044 EAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQ 4103
Query: 4002 LLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLF 4061
L+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4104 LMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYEA-- 4157
Query: 4062 YREVSEDRRQDL-LSRYRA--STLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREA 4118
YR+ D + L LS +T+ + S++
Sbjct: 4158 YRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMI----------------------- 4194
Query: 4119 LRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIE 4178
+ R GR + D +A + R+A L ++ +GTL + L+
Sbjct: 4195 ---------IDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS---- 4237
Query: 4179 EAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ 4238
G++G + G + + A +R Q
Sbjct: 4238 -----------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLA 4268
Query: 4239 TLRDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDL 4290
+ D T E G G VS+ + + + + LL AQ G +
Sbjct: 4269 SWSDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI----- 4321
Query: 4291 VAVLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTL 4343
+ T ER ++ +GL ++ ++ + G P T ++
Sbjct: 4322 ------IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4375
Query: 4344 QEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQA 4403
+ ++ +R+LE G++ P D PGR + + +A+ +G + TA L + A
Sbjct: 4376 KGWLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGA 4430
Query: 4404 ATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 4451
+ ++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4431 YSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4479
Score = 852 bits (2202), Expect = 0.0
Identities = 715/2192 (32%), Positives = 1042/2192 (47%), Gaps = 408/2192 (18%)
Query: 1960 VNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEAL----RLLEVQVATGG 2015
+ +E + LK+E T ++ +T QA+Q+ + + ++L R +E + A
Sbjct: 2462 LQQEAKLLQLKSEEMQTVQQEQLLQET----QALQQSFLSEKDSLLQRERFIEQEKAKLE 2517
Query: 2016 VI---DPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERC 2072
+ + +L E ++ + ++ L++ + R+R + + ELQ+
Sbjct: 2518 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577
Query: 2073 RPQEDTGWVLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVT 2132
+ + +L N+ R+ + +E RA A E+T + K
Sbjct: 2578 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL----------- 2626
Query: 2133 EEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSAII 2192
+ R AL A E +H F G+RR+++A L + I+
Sbjct: 2627 ------------PNGRDALDGPA---------AEAEPEHS-FDGLRRKVSAQRLQEAGIL 2664
Query: 2193 TEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKG 2252
+ E LQ L G +T EL + V+ YL+G S IAG+L+ A + EK+S+Y A+ +
Sbjct: 2665 SAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN-----EKLSVYAALQRQ 2719
Query: 2253 VLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTD 2312
+L PGTAL+LLEAQAA+GF++DPVRN RL+V E V GVVG E+ KLLSAERAVTGY D
Sbjct: 2720 LLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKD 2779
Query: 2313 PYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2372
PYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM
Sbjct: 2780 PYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2839
Query: 2373 NRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL---AGRGSAVHQLSE 2429
NRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L A +G +
Sbjct: 2840 NRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDS 2899
Query: 2430 ELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATL 2489
E R A V+ G QG++V++WE++ + ++R+DLL ++R G +TVE++ +
Sbjct: 2900 EARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKII 2959
Query: 2490 TSLLAQAQAQAR----------AEAEAGSPRPDPREALR-----------AATMEVKVGR 2528
+++ + + + R AE R RE + A ++
Sbjct: 2960 ITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 3019
Query: 2529 LRGRAV--PVWDVLASGYVS--RAAREELL----------AEFGSGTLDLPALTRRLTAI 2574
LRG V VW A +S A +++LL A+ G+G + PA + RLT
Sbjct: 3020 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLT-- 3077
Query: 2575 IEEAEEAPGARPQ--------------------------LQDARRG--PREPG------- 2599
++EA A P+ Q ++G PRE G
Sbjct: 3078 VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQ 3137
Query: 2600 PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQEQTLRDATM-EVQR 2647
+ G D +S R G + ET A +A A A T AT E+Q+
Sbjct: 3138 LSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQ 3197
Query: 2648 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVS 2707
+ + + S + AR++EL ++ A E+T +
Sbjct: 3198 RCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------RETFEKTPVEVPVGG 3245
Query: 2708 FRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV-----TEMDSVKRYLEGTS 2758
F+G R V+ EL +S E LR G T+++V T ++ V+ +
Sbjct: 3246 FKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERL 3303
Query: 2759 CIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDP 2809
+G+ VPA + + E++ + K + G+ LL+ +
Sbjct: 3304 SFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLE 3363
Query: 2810 VRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP---------------------- 2847
++S+ EA+ G++ LL A+ A DP
Sbjct: 3364 DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELH 3423
Query: 2848 ----------------YTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRV 2891
Y+G ISLFQAMQK L++R+HGIRLLEAQIATGG+IDPVHSHRV
Sbjct: 3424 EQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRV 3483
Query: 2892 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL 2951
PVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+TGL +L L
Sbjct: 3484 PVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL 3543
Query: 2952 AGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYREVSEDRRQD 3004
G A EE R A + ++ PG G+ G ++S+WE++ + E++R
Sbjct: 3544 KGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQ 3603
Query: 3005 LLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EAGSPRPDPR 3048
L++ ++AG +T E + + ++ + + + R A EA +
Sbjct: 3604 LMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETY 3663
Query: 3049 EALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYVSG-AAREE 3086
LR T ++ G + G +P ++ L G +S AR
Sbjct: 3664 NLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLL 3723
Query: 3087 LLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQ 3146
L A+ +G L P RLT ++EA P+L D A G D Q
Sbjct: 3724 LEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTGYRDPYTEQ 3778
Query: 3147 REGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRD 3206
+ +E A R + L + R F P+ V YL++ D
Sbjct: 3779 TISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRGYLNKDTHD 3835
Query: 3207 ELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------------KVS 3241
+ L + V + V T+ERLS K++
Sbjct: 3836 Q-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT 3884
Query: 3242 FRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPA 3301
FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSCIAGV V A
Sbjct: 3885 FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSCIAGVFVDA 3942
Query: 3302 KDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVG 3361
+E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEEAV G+VG
Sbjct: 3943 -----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVG 3997
Query: 3362 GEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVH 3421
E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIATGG+IDP
Sbjct: 3998 PEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEE 4057
Query: 3422 SHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLY 3481
SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+QL+ RC+ DP TGL
Sbjct: 4058 SHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLC 4117
Query: 3482 MLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLS 3541
+L L + S+ R V P + G+ +SV+E
Sbjct: 4118 LLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE----------------- 4156
Query: 3542 RYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRA 3601
YR G + + T L Q E S + + R GR
Sbjct: 4157 AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------DGVVKSMIIDRRSGRQ 4202
Query: 3602 VPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWR 3661
+ D +A + +A L ++ +GTL + L+
Sbjct: 4203 YDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS--------------------- 4237
Query: 3662 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG- 3720
G++G + G + + A +R Q + D T E G G
Sbjct: 4238 ------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEET--GPVAGI 4283
Query: 3721 ------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVAVLTRVIEETEER--L 3771
VS+ + + + + LL AQ G + + T ER +
Sbjct: 4284 LDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI-----------IDPSTGERFPV 4332
Query: 3772 SKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTS 3826
+ +GL ++ ++ + G P T ++ + ++ +R+LE
Sbjct: 4333 TDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQY 4392
Query: 3827 CIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVE 3886
G++ P D PGR + + +A+ +G + TA L + A + ++ P L++S +
Sbjct: 4393 LTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYK 4447
Query: 3887 EAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3917
+A+ +V +LL +A ++ GY PY+
Sbjct: 4448 DALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4479
Score = 727 bits (1876), Expect = 0.0
Identities = 710/2292 (30%), Positives = 1038/2292 (45%), Gaps = 316/2292 (13%)
Query: 3017 EELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLAS 3076
EE+ A S A +A E E G R + + LR+ + ++ R R + +
Sbjct: 1925 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE-QAELEAARQRQLAAEEERRR 1983
Query: 3077 GYVSGAAREELLAEFGSGTLDLPAL--TRRLTAIIEEAE------EAPGARPQLQDAWRG 3128
++ L AE + AL RL A +EEA E AR QLQ A
Sbjct: 1984 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEA 2042
Query: 3129 PREPGPAGRGDGDSGRSQREGQGEGETQEAAAA-------AAAARRQEQTLRDATMEVQR 3181
++ A Q+E + + Q+ + A AARR + +A ++ +R
Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2102
Query: 3182 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAV-LTRVIEETEERLSKV 3240
Q R + EA R + A+ A A A L + E+ R ++
Sbjct: 2103 EAAQSR----------RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2152
Query: 3241 SFRGLR-RQVSASELHTSGILGPETLRDLAQGTKTLQ----EVTEMDSVKRYL-EGTSCI 3294
LR +Q + +E+ +TLR AQ + L ++ E D K L E +
Sbjct: 2153 EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRL 2212
Query: 3295 AGVLVPAKDQPGRQEK--------MSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 3346
A Q + E+ M + + AL+L + F+ +
Sbjct: 2213 KAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEK 2272
Query: 3347 LRLSVEEAVAAGVVGGE----------------------IQEKLLSAERAVTGYTDPYTG 3384
++ EEA V E ++EK+ + + A +
Sbjct: 2273 MKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2332
Query: 3385 QQ---ISLFQA---------MQKDLIVREHGI-RLLEA----QIATGGVIDPVHSHRVPV 3427
QQ ++ QA M + L G R LEA Q+ + + +
Sbjct: 2333 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2392
Query: 3428 DVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLL--RRCVPDPDTGLYMLQL 3485
A R D + R A+ + + T E +T VQ L +R D D +
Sbjct: 2393 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI 2452
Query: 3486 AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRA 3545
A +L +E + L + Q Q + + L +SE + LL R R
Sbjct: 2453 AELEREKEKLQQEAK--LLQLKSEEMQTVQQEQLLQETQALQQSFLSE--KDSLLQRERF 2508
Query: 3546 GTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPV- 3604
+L +A+AQ Q R E + + + A+ME R V
Sbjct: 2509 IEQEKAKLEQLFQDEVAKAQ-QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2567
Query: 3605 --WDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRG 3662
+ L +EELLAE + L +L + E+ A ++ +
Sbjct: 2568 RKQEELQQLEQQRRQQEELLAE------ENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2621
Query: 3663 PREPGPAGRG--DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG 3720
+ P GR DG + ++ E +G ++ +A R QE + A E+QR QG
Sbjct: 2622 ATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ----RLQEAGILSAE-ELQR-LAQG 2675
Query: 3721 RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 3780
+ E R E + + G + L+ ++ T E+LS + L+
Sbjct: 2676 HTT----------VDELARREDVRHYLQGRSSIAGLL------LKATNEKLSV--YAALQ 2717
Query: 3781 RQVSA---------SELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 3831
RQ+ + ++ + +L P R L + V + + L + G
Sbjct: 2718 RQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGY 2777
Query: 3832 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 3891
P Q ++S++QAM KG++ + LLEAQ ATG VIDPV + R+ V+ A
Sbjct: 2778 KDPYTGQ-----QISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRR 2832
Query: 3892 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEA--QIATGG 3949
G E+ L G+ DP T + ++ Q +++ + E G+ LL + A GG
Sbjct: 2833 GYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGG 2892
Query: 3950 VI--------DPVHSHRVPVDVAYRRG------------YFDEEMNRVLADPSDDTKGFF 3989
+ D V +G YF E R L +
Sbjct: 2893 ELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITV 2952
Query: 3990 DPNTHENLTYVQL-----------LRRCVPDP--------DTGLYMLQLAGRGSAVHQLS 4030
+ +T V+ LR VP D LY QL +V ++
Sbjct: 2953 EKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQ-QLQRGERSVRDVA 3011
Query: 4031 E--ELRCALRDARVTPGSGALQ-GQSVSVWELLFYREVSEDRRQDLLSRYRASTLTVEEL 4087
E +R ALR A V G + GQ +S++ L ++DLL A L +
Sbjct: 3012 EVDTVRRALRGANVIAGVWLEEAGQKLSIYNAL---------KKDLLPSDMAVALLEAQA 3062
Query: 4088 GAT-LTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGR--LRGRAVPVWDVLAS 4144
G + A+ AG P+ E L +A V R G++V ++ L
Sbjct: 3063 GTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKK 3122
Query: 4145 GYVSRAAREELL-AEFGSGTLDLPALTRRLTAII--------EEAEEAPGARPQLQDAWR 4195
G + R LL A+ +G + P+ + R+ + EE A A A+
Sbjct: 3123 GLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYS 3182
Query: 4196 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ---------TLRDATME 4246
P PA G+ + R Q G + + AA RQE+ T +E
Sbjct: 3183 DPSTGEPATYGELQ--QRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVE 3240
Query: 4247 VQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEE-RL 4305
V G F+GR V+VW+++ S Y + +R ELL Q G + + ++ +L ++EE E R
Sbjct: 3241 VPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQ 3300
Query: 4306 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 4365
++SF GLR V ASEL SG+L L G T+++++E+ SV+ L+G+ C+AG+
Sbjct: 3301 ERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGI 3360
Query: 4366 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 4425
+ +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL V EAV A
Sbjct: 3361 YLE-----DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKA 3415
Query: 4426 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 4485
GVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATGG+I
Sbjct: 3416 GVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGII 3475
Query: 4486 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 4545
DPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+
Sbjct: 3476 DPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPE 3535
Query: 4546 TGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYRE 4598
TGL +L L G A EE R A + ++ PG G+ G ++S+WE++
Sbjct: 3536 TGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDL 3595
Query: 4599 VSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EA 4642
+ E++R L++ ++AG +T E + + ++ + + + R A EA
Sbjct: 3596 IPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEA 3655
Query: 4643 GSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYV 4681
+ LR T ++ G + G +P ++ L G +
Sbjct: 3656 RIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLL 3715
Query: 4682 SG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRG 4740
S AR L A+ +G L P RLT ++EA P+L D A G
Sbjct: 3716 SAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTG 3770
Query: 4741 DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSS 4800
D Q + +E A R + L + R F P+ V
Sbjct: 3771 YRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRG 3827
Query: 4801 YLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------- 4840
YL++ D+ L + V + V T+ERLS
Sbjct: 3828 YLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLP 3876
Query: 4841 -----KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSC 4895
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSC
Sbjct: 3877 LSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSC 3934
Query: 4896 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 4955
IAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEE
Sbjct: 3935 IAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 3989
Query: 4956 AVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 5015
AV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIAT
Sbjct: 3990 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4049
Query: 5016 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRAT 5075
GG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTYLQL++R
Sbjct: 4050 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4109
Query: 5076 LDPETGLLFLSL 5087
DP+TGL L L
Sbjct: 4110 TDPQTGLCLLPL 4121
Score = 619 bits (1597), Expect = e-176
Identities = 476/1531 (31%), Positives = 736/1531 (48%), Gaps = 227/1531 (14%)
Query: 40 ARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKAL 99
A IAGV++E +GQ S+Y A+++ LLP+ + ALLEAQA TG ++D A L V +A+
Sbjct: 3023 ANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEAV 3082
Query: 100 QQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGG 159
+ GLVG E EKLL+AE+A TGY DPY G+ ++LFQA+ K ++ R G L+ QL+TGG
Sbjct: 3083 RAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTGG 3142
Query: 160 LVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCV 219
+VDP++ V + AC +G LD ET LS P + +P+T E TY +L +RC
Sbjct: 3143 IVDPSKSHRVPLDVACARGCLDEETSRALS--APRADAKAYSDPSTGEPATYGELQQRCR 3200
Query: 220 RAPGSGLALLPL------------------KITFRS----------MGGAVSAAELLEVG 251
+GL+LLPL + TF G V+ EL+
Sbjct: 3201 PDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISSE 3260
Query: 252 ILD-EQAVQGLREGRLAAV--------------DVSARAEVRRYLEGTGS--------VA 288
EQ + LR+ R V +V + R G + +
Sbjct: 3261 YFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLAS 3320
Query: 289 GVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAG-- 346
GV+ + + + + L +G+ LL+ + T +++ + EA+R G
Sbjct: 3321 GVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGLL 3380
Query: 347 -----------------LVSPELHEQLLVAE-------------------QAVTGHHDPF 370
LV P +++L V E +AVTG+ DP+
Sbjct: 3381 RATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDPY 3440
Query: 371 SGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQR 430
SGS I LFQAM+KGLV R +RLL+AQ+ATGG++ P R+P++ A + G E+ R
Sbjct: 3441 SGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMNR 3500
Query: 431 QLSQ-----AGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPP-FIK 484
L+ G F TH L Y QLL CV DPETGL LPL G + + + +
Sbjct: 3501 VLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVETTQVYTE 3560
Query: 485 YSTRQALSTATATV-SVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAA 543
TR+A + G G +SLWE++ S+ I EQRA L +Q G ++ E++
Sbjct: 3561 EETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMII 3620
Query: 544 ELSATLEQAAATAR---VTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLA 600
+ +E+ + ++ +R +T +L +A II + Y L G + ++
Sbjct: 3621 IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAE 3680
Query: 601 SAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANK 660
SA YL GTG +AG+ LPGS++ LSIY+A KGLL A +LLEAQAATGF++DP +
Sbjct: 3681 SAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGE 3740
Query: 661 GHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLL 720
+V+EA+R ++GP++ +LLSAERAVTGY DPYT Q ISLFQAM+K LI E +RLL
Sbjct: 3741 RLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLL 3800
Query: 721 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQ 780
+AQ+ATGG++DP +P++VAY+RGY ++ + L +PS + + + DP+T E L+Y Q
Sbjct: 3801 DAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQ 3859
Query: 781 LLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSE 840
LL RC RD TG LLPLS A + F+ L ++++ EL+ S+
Sbjct: 3860 LLRRCRRDDGTGQLLLPLS--------DARKLTFRGL----------RKQITMEELVRSQ 3901
Query: 841 YFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQ 900
E QL E + K LE T A + + A + R++V+Q ++ GII
Sbjct: 3902 VMDEATALQLREGLTSIEEVTKNLQKFLEG-TSCIAGVFVDATKERLSVYQAMKKGIIRP 3960
Query: 901 QLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVA 960
++L A G V G +L++ +A+R ++GP
Sbjct: 3961 GTAFELLEAQ-------------------AATGYVIDPIKGLKLTVEEAVRMGIVGPEFK 4001
Query: 961 LALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQV 1020
LL A+ A DP+S + +S+ +A+++G++ + RL A+ A G DP ++
Sbjct: 4002 DKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRL 4061
Query: 1021 SVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSS 1080
V A K+GL E L + T G DP + +L
Sbjct: 4062 PVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENL---------------------- 4099
Query: 1081 SETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPT--EEQVQRSLQAVPGA 1138
+Y QL+E C D +GL LLPL E T + V++ +
Sbjct: 4100 -------------TYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDP 4146
Query: 1139 KDGTSLWDLLSSCHFTEEQRRGLLE-----DVQEGRTTVPQLLASVQRWVQETKLLAQAR 1193
+ G + E R+GL++ ++ E ++ S V ++ ++ +
Sbjct: 4147 ETGKEM-------SVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRR- 4198
Query: 1194 VMVPGPRGEVPAVWLLDAGIITQETLEALAQGTQSPAQVAE------------------- 1234
G + ++ + +I + L+ GT S + A+
Sbjct: 4199 ---SGRQYDIDDA--IAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSS 4253
Query: 1235 -----QPAV---KACLWG-----TGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLE 1281
PAV + W TG VAG+L + K SI +A+ L+ GQRLLE
Sbjct: 4254 SSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLE 4313
Query: 1282 AQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQA 1341
AQ +G ++DP +R V DAV GLV + + +++ A++A G+ DP ++ +S QA
Sbjct: 4314 AQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQA 4373
Query: 1342 MEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNK 1401
++KG + G L+VQ TGG+++P +P A + G +D +T+Q L V +K
Sbjct: 4374 LKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSK 4433
Query: 1402 FFFDPSARDQVTYQQLRERCVCDSETGLLLL 1432
+ P + +++Y+ +R + + TGL LL
Sbjct: 4434 YLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4464
Score = 350 bits (897), Expect = 3e-95
Identities = 288/927 (31%), Positives = 451/927 (48%), Gaps = 110/927 (11%)
Query: 4243 ATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE 4302
AT+ G+FQG+ V++W+++ S Y + +R +LL Q G + + ++ ++ V+EE E
Sbjct: 2908 ATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE 2967
Query: 4303 ERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCI 4362
++ ++ F GLR V A+EL S ++ E + L +G +++++V E+D+V+R L G + I
Sbjct: 2968 QK-GRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRALRGANVI 3026
Query: 4363 AGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEA 4422
AGV + Q K+SIY A+ K +L A+ LLEAQA TG +IDP + RL+V+EA
Sbjct: 3027 AGVWLEEAGQ-----KLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEA 3081
Query: 4423 VAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 4482
V AG+VG E EKLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++TG
Sbjct: 3082 VRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTG 3141
Query: 4483 GVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVP 4542
G++DP SHRVP+DVA RG DEE +R L+ P D K + DP+T E TY +L +RC P
Sbjct: 3142 GIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRCRP 3201
Query: 4543 DPDTGLYMLQLAGRGSAVHQLSEELRCALRDARV---TPGS---GALQGQSVSVWELLFY 4596
D TGL +L L+ + + Q EEL L+ TP G +G++V+VWEL+
Sbjct: 3202 DQLTGLSLLPLSEKAARARQ--EELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3259
Query: 4597 REVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAE-AGSPRPDPREAL-- 4653
+ ++RQ+LL ++R G +TVE++ L +++ + + + +G P P L
Sbjct: 3260 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3319
Query: 4654 -----RAATMEVKVGR---------------LRGRA-------------VPVWDVLASGY 4680
RA ++K G+ L+G V +++ + G
Sbjct: 3320 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3379
Query: 4681 VSGAAREELL-AEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGR 4739
+ LL A+ +G L P +RL + EA +A P+L + E G
Sbjct: 3380 LRATTAALLLEAQAATGFLVDPVRNQRL--YVHEAVKAGVVGPELHEQLLSA-EKAVTGY 3436
Query: 4740 GDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQF----QGRPVSVWD 4795
D SG + Q A ++ +R ++ G V V
Sbjct: 3437 RDPYSGSTISLFQ---------AMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3487
Query: 4796 VLFSSYLSEARRDELLAQHAAGALGLPD--------LVAVLTRVIEETEERLSKVSFRGL 4847
Y SE + +LA + G D +L R +E+ E L + +G
Sbjct: 3488 AYQRGYFSE-EMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGA 3546
Query: 4848 RRQ--VSASELHTSGILG---PETLRDLAQG------TKTLQEVTEMDSVK--------- 4887
+ V ++++T ET D+ G T +L EV + D +
Sbjct: 3547 EKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMA 3606
Query: 4888 -----RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFV 4942
R + I + + K + RQ+ ++ Y V R TA L EA+ +
Sbjct: 3607 DFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDY----VRRRLTAEDLFEARIISLET 3662
Query: 4943 IDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 5002
+ +R S+ EA+ A E L +V G P + Q +S++QA++K L+
Sbjct: 3663 YNLLREGTRSLREALEA-----ESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSA 3717
Query: 5003 EHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTH 5062
E LLEAQ ATG ++DPV R+ VD A R+G E++ L G+ DP T
Sbjct: 3718 EVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTE 3777
Query: 5063 ENLTYLQLLQRATLDPETGLLFLSLSL 5089
+ ++ Q +++ + E L L L
Sbjct: 3778 QTISLFQAMKKELIPTEEALRLLDAQL 3804
Score = 347 bits (889), Expect = 2e-94
Identities = 202/360 (56%), Positives = 242/360 (67%), Gaps = 25/360 (6%)
Query: 4746 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 4801
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2534 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2593
Query: 4802 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 4848
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2594 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2650
Query: 4849 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 4908
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2651 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2707
Query: 4909 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 4968
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2708 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2765
Query: 4969 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 5028
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2766 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2825
Query: 5029 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLS 5088
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLL+R DPETGL L L+
Sbjct: 2826 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2885
Score = 254 bits (648), Expect = 2e-66
Identities = 137/307 (44%), Positives = 206/307 (67%), Gaps = 8/307 (2%)
Query: 4784 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE--ERLSK 4841
G G +S+W+V+ S + E +R +L+A AG + ++ ++ +IE+TE +
Sbjct: 3578 GSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGL 3637
Query: 4842 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 4901
S+ +RR+++A +L + I+ ET L +GT++L+E E +S YL GT +AGV +
Sbjct: 3638 ASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYL 3697
Query: 4902 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 4961
P G ++ +SIYQA+ KG+L A +LLEAQAATGF++DPV+ RL+V+EAV G+
Sbjct: 3698 P-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGL 3752
Query: 4962 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 5021
VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI E +RLL+AQ+ATGG++DP
Sbjct: 3753 VGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDP 3812
Query: 5022 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETG 5081
+P++VAY+RGY +++ + L++PS + + + DP+T E L+Y QLL+R D TG
Sbjct: 3813 RLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQLLRRCRRDDGTG 3871
Query: 5082 LLFLSLS 5088
L L LS
Sbjct: 3872 QLLLPLS 3878
Score = 107 bits (267), Expect = 3e-22
Identities = 73/212 (34%), Positives = 111/212 (52%), Gaps = 5/212 (2%)
Query: 4347 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4406
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4265 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4319
Query: 4407 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 4466
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4320 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4379
Query: 4467 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 4526
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4380 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4439
Query: 4527 THENLTYVQLLRRCVPDPDTGLYMLQLAGRGS 4558
T ++Y L R + + TGL +L+ A + +
Sbjct: 4440 TKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4471
Score = 107 bits (266), Expect = 4e-22
Identities = 73/210 (34%), Positives = 109/210 (51%), Gaps = 5/210 (2%)
Query: 4881 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4940
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4265 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4319
Query: 4941 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 5000
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4320 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4379
Query: 5001 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 5060
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4380 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4439
Query: 5061 THENLTYLQLLQRATLDPETGLLFLSLSLQ 5090
T ++Y L R+ ++ TGL L + Q
Sbjct: 4440 TKLKISYKDALDRSMVEEGTGLRLLEAAAQ 4469
Score = 105 bits (261), Expect = 2e-21
Identities = 69/217 (31%), Positives = 114/217 (52%), Gaps = 3/217 (1%)
Query: 13 GTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQ 72
G++S+ S P L + + P + +AG+ + + S+ AM + L+ GQ
Sbjct: 4251 GSSSSYPIS-PAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQ 4309
Query: 73 ALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLA 132
LLEAQA TGG++D + G+ PV+ A+ +GLV + +++ A++A G+ DP K++
Sbjct: 4310 RLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMS 4369
Query: 133 LFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLLDRETWHKLSELE 192
QA+ K + GQ +LEVQ TGGL++P V + A +G +D T KL ++
Sbjct: 4370 AAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV- 4428
Query: 193 PGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALL 229
G P T +++Y L+R + G+GL LL
Sbjct: 4429 -GAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4464
Score = 70.5 bits (171), Expect = 4e-11
Identities = 61/227 (26%), Positives = 102/227 (44%), Gaps = 17/227 (7%)
Query: 4832 IEETEERLS--KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 4889
++ T+ERLS + +G+ R +A EL + + + T++E M V
Sbjct: 3940 VDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPE 3999
Query: 4890 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 4949
+ A V P + +S++QAM KG++ + LLEAQ ATG +IDP +
Sbjct: 4000 FKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESH 4059
Query: 4950 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 5009
RL VE A G+ E+ E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4060 RLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLL 4119
Query: 5010 -------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 5041
E + ++ ++DP + V AYR+G D +
Sbjct: 4120 PLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4166
Score = 60.8 bits (146), Expect = 3e-08
Identities = 32/119 (26%), Positives = 61/119 (51%)
Query: 4971 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 5030
L ++ G T +++S++ A+Q+ L+ + LLEAQ A+G ++DPV + R+ V+
Sbjct: 2692 LQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVN 2751
Query: 5031 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSL 5089
A + G E++ L G+ DP T + ++ Q +Q+ + E G+ L +
Sbjct: 2752 EAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQI 2810
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4254 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4310
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4200 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4255
Query: 4311 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4359
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4256 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4315
Query: 4360 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4386
+C G++ P+ + P + KMS QA+
Sbjct: 4316 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4375
Query: 4387 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4446
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4376 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4435
Query: 4447 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 4487
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4436 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4477
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4788 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4844
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4200 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4255
Query: 4845 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4893
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4256 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4315
Query: 4894 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4920
+C G++ P+ + P + KMS QA+
Sbjct: 4316 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4375
Query: 4921 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4980
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4376 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4435
Query: 4981 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 5021
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4436 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4477
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 1268 bits (3280), Expect = 0.0
Identities = 798/1967 (40%), Positives = 1134/1967 (57%), Gaps = 218/1967 (11%)
Query: 1511 AAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLEGG 1570
AAE +P + +F GLR++VSA+ L A ++S + L L+QG TTV E+A + V+ L+G
Sbjct: 2641 AAEAEP-EHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGR 2699
Query: 1571 NFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFK 1630
+ IAG+L++ T E++S+ AL+R +L PGTAL+LLEAQAA+GF++DP NR+LTV EA K
Sbjct: 2700 SSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVK 2759
Query: 1631 AGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGI 1690
G+ G E + KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGG+
Sbjct: 2760 EGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGV 2819
Query: 1691 IDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 1750
IDPVHSHRVPVDVAYR GYFDEEMNR+LADPSDDTKGFFDPNTHENLTYLQLLERCVEDP
Sbjct: 2820 IDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 2879
Query: 1751 ETGLYLLQI---IKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTE 1807
ETGL LL + KG VY + R V + T G+F + V+ W++++S YFT
Sbjct: 2880 ETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTA 2939
Query: 1808 DRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLFNSRVIDQ 1867
+++R+L++++ +EK+++II T +EE E Q + +R V AA+L SRVID+
Sbjct: 2940 EQRRDLLRQFRTGRITVEKIIKIIITVVEEQE-QKGRLCFEGLRSLVPAAELLESRVIDR 2998
Query: 1868 KTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFA 1927
+ L+ G + ++ ++ V+ L G++ IAGV + + +S++ A +K+L+P+ A
Sbjct: 2999 ELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMA 3058
Query: 1928 TWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTI 1987
LLEAQA TG ++DP T +L+VDEAV GLV E E+LL AE+A TGYRDP TG ++
Sbjct: 3059 VALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSV 3118
Query: 1988 PLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQ 2047
LFQA++K LI + + LRLL+ Q++TGG++DP HR+PL+ A RGCL ++ +S
Sbjct: 3119 SLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAP 3178
Query: 2048 KHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVN-KAAR---DSEHIDDETRRAL 2103
+ K + DP+T E +Y ELQ+RCRP + TG L P++ KAAR + + + + R
Sbjct: 3179 RADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETF 3238
Query: 2104 EAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIE 2163
E VE+ VG F+G+ T+W L++SEY T E++ +L+R +RT + ++ V ++++ ++E
Sbjct: 3239 EKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRT-GKVTVEKVIKILITIVE 3297
Query: 2164 KQET-SNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEG 2222
+ ET + L F G+R + ASELL+S +++ + L+ G++T ++L E V+ L+G
Sbjct: 3298 EVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQG 3357
Query: 2223 TSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLS 2282
+ C+AG+ + +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL
Sbjct: 3358 SGCLAGIYL-----EDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLY 3412
Query: 2283 VEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQ 2342
V E V AGVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQ
Sbjct: 3413 VHEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQ 3472
Query: 2343 IATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLR 2402
IATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL
Sbjct: 3473 IATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLE 3532
Query: 2403 RCVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVW 2455
RCV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+W
Sbjct: 3533 RCVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLW 3592
Query: 2456 ELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAE 2503
E++ + E++R L++ ++AG +T E + + ++ + + + R
Sbjct: 3593 EVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLT 3652
Query: 2504 A----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWD 2538
A EA + LR T ++ G + G +P ++
Sbjct: 3653 AEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQ 3712
Query: 2539 VLASGYVS-RAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDARRGPRE 2597
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3713 ALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER 3770
Query: 2598 PGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSV 2657
A G D Q + +E A R + L + R F P+ V
Sbjct: 3771 ---AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV 3826
Query: 2658 WDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS------------- 2704
YL++ D+ L + V + V T+ERLS
Sbjct: 3827 --AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDG 3873
Query: 2705 ------------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKR 2752
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ ++++
Sbjct: 3874 TGQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQK 3931
Query: 2753 YLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 2812
+LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++
Sbjct: 3932 FLEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKG 3986
Query: 2813 LRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRL 2872
L+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRL
Sbjct: 3987 LKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRL 4046
Query: 2873 LEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYV 2932
LEAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+
Sbjct: 4047 LEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYL 4106
Query: 2933 QLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELL 2992
QL+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4107 QLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE-- 4160
Query: 2993 FYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALR 3052
YR G + + T L Q E S
Sbjct: 4161 ---------------AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------D 4191
Query: 3053 AATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEA 3112
+ + R GR + D +A + +A L ++ +GTL + L+
Sbjct: 4192 GVVKSMIIDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS------ 4241
Query: 3113 EEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTL 3172
G++G + G + + A +R Q +
Sbjct: 4242 ---------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASW 4274
Query: 3173 RDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVA 3224
D T E G G VS+ + + + + LL AQ G +
Sbjct: 4275 SDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI------- 4325
Query: 3225 VLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQE 3277
+ T ER ++ +GL ++ ++ + G P T ++ +
Sbjct: 4326 ----IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKG 4381
Query: 3278 VTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 3337
++ +R+LE G++ P D PGR + + +A+ +G + TA L + A +
Sbjct: 4382 WLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYS 4436
Query: 3338 GFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3383
++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4437 KYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4483
Score = 1127 bits (2914), Expect = 0.0
Identities = 724/1911 (37%), Positives = 1065/1911 (55%), Gaps = 110/1911 (5%)
Query: 522 EQRAMLAQQYQEGTLSVEKL-AAELSAT---------LEQAAATARV--TFSGLRDTVTP 569
EQ +L +Q++ E++ A++++AT L+ AA A +F GLR V+
Sbjct: 2600 EQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSA 2659
Query: 570 GELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEA 629
L +A I+ + +RL G T ++ + YLQG IAGLLL + E+LS+Y A
Sbjct: 2660 QRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAA 2719
Query: 630 RCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVT 689
+ LL PGTALILLEAQAA+GF++DP N+ +V EA++ V+GP++ KLLSAERAVT
Sbjct: 2720 LQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVT 2779
Query: 690 GYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 749
GY DPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF
Sbjct: 2780 GYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 2839
Query: 750 DQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSP----- 804
D+ +N +L DPSDDTKGFFDPNTHENLTYLQLLERCV DPETGL LLPL+ +
Sbjct: 2840 DEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELV 2899
Query: 805 LVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQV 864
DS + F+ +S +G+FQG+ V+ WE+INSEYF+ +RR LLR++R +T+ ++
Sbjct: 2900 YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKI 2959
Query: 865 AKLLEA---ETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDG 921
K++ E +++ + LRS V +LLE+ +ID++L Q+ G S + +D
Sbjct: 2960 IKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDT 3019
Query: 922 VRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPES 981
VRR L G + GV L +GQ+LS+Y A+++ LL +A+ALLEAQA TG I+DP +
Sbjct: 3020 VRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSAR 3079
Query: 982 LSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLE 1041
L+VDEAVR G+VGPE + +L AE A+ G+RDP++G+ VS+FQA+KKGLIP EQ RLL+
Sbjct: 3080 LTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLD 3139
Query: 1042 AQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSS---SSETFPTPDGQGRTSYAQL 1098
AQ++TGGI+DP+ H +P+ VA RG +D+E ALS+ ++ + P +Y +L
Sbjct: 3140 AQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGEL 3199
Query: 1099 LEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQA------------VPGAKDGT-SLW 1145
+ C D+ +GL LLPL E A A +E++ LQA V G K T ++W
Sbjct: 3200 QQRCRPDQLTGLSLLPLSEKA-ARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVW 3258
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+SS +FT EQR+ LL + G+ TV +++ + V+E + L Q R+ G R VPA
Sbjct: 3259 ELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPA 3318
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQA 1265
LL +G++++ E L G + ++E +V+ L G+GC+AG+ L+ + K SI +A
Sbjct: 3319 SELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEA 3378
Query: 1266 VRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAA 1325
+R GLL LLEAQ A+GFLVDP+ NQRL V +AVK G+VG EL EQL AE+A
Sbjct: 3379 MRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVT 3438
Query: 1326 GYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLL 1385
GY DPYS +++SL+QAM+KGLV + G+ LL+ Q+ATGG++DPVH +P A + G
Sbjct: 3439 GYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYF 3498
Query: 1386 DTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDH 1445
+ ++VL D K FFDP+ + +TY+QL ERCV D ETGL LLPL EV +
Sbjct: 3499 SEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVET 3558
Query: 1446 TAV--------ALRAMKVPV-STGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAA 1496
T V A ++ + G G ++SLW+++ S+ + ++R +L+A ++GR
Sbjct: 3559 TQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVT 3618
Query: 1497 ALRQVVSAVTALVEAAE--RQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTV 1554
R ++ + ++E E RQ A++ +R++++A DLF A++IS +T + L +GT ++
Sbjct: 3619 KERMII-IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSL 3677
Query: 1555 KEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFI 1614
+E E +S L G +AGV + G+++ +SI +AL++ +L A +LLEAQAATGF+
Sbjct: 3678 REALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFL 3737
Query: 1615 IDPAENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 1674
+DP + +LTV+EA + G+ G E + +LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3738 LDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPT 3797
Query: 1675 EHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTH 1734
E +RLL+AQ+ATGGI+DP +P++VAY+ GY +++ + L++PS+ + + DP+T
Sbjct: 3798 EEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSE-VRSYVDPSTD 3856
Query: 1735 ENLTYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVV 1794
E L+Y QLL RC D TG LL + A+ R + +
Sbjct: 3857 ERLSYTQLLRRCRRDDGTGQLLLPL--------------------SDARKLTFRGLRKQI 3896
Query: 1795 SFWDLLSSPYFTED---RKRELIQEYGAQSGGLEKLLE-------IITTTIEETETQNQG 1844
+ +L+ S E + RE + + L+K LE + +E + Q
Sbjct: 3897 TMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQA 3956
Query: 1845 IKVAAIRG----EVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIA 1900
+K IR E+ A VID L V + E L +
Sbjct: 3957 MKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVT 4016
Query: 1901 GVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLV 1960
G P + +++SL +A +K LI LLEAQ ATG ++DP +L V+ A GL
Sbjct: 4017 GYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLF 4076
Query: 1961 NEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLL------------- 2007
+EE+ E L G+ DP T + + Q M++ + + L LL
Sbjct: 4077 DEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSS 4136
Query: 2008 --EVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSY 2065
V+ ++DP+ + + AYR+G + Y +S+Q+ + ++ V
Sbjct: 4137 KSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKS 4196
Query: 2066 RELQERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALE----AEQVEITVGRFRGQKPT 2121
+ R Q D + + K D +D L A+ + G FR + +
Sbjct: 4197 MIIDRRSGRQYD---IDDAIAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSS 4253
Query: 2122 LWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQI 2181
+ + + + QL + T L E +EK S + + I
Sbjct: 4254 VGSSSSYPISPAVSRTQLA-SWSDPTEETGPVAGILDTETLEK--VSITEAMHRNLVDNI 4310
Query: 2182 TASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQE 2241
T LL + T ++ R + + V + + +A + P +
Sbjct: 4311 TGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKT 4370
Query: 2242 KMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLL 2301
KMS QA+ KG L LE Q TG +I+P R+ ++E + G V + +KL
Sbjct: 4371 KMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLR 4430
Query: 2302 SAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 2351
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4431 DVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4481
Score = 1054 bits (2725), Expect = 0.0
Identities = 630/1557 (40%), Positives = 924/1557 (59%), Gaps = 83/1557 (5%)
Query: 869 EAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCG 928
EAE + D LR +V+ +L EAGI+ + L ++ G + + L + VR YL G
Sbjct: 2643 EAEPEHSFD----GLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQG 2698
Query: 929 LGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAV 988
++ G+ L + ++LS+Y A++++LL P AL LLEAQAA+G ++DP L+V+EAV
Sbjct: 2699 RSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAV 2758
Query: 989 RRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGG 1048
+ GVVGPEL+ +L AE A+ G++DP++G+Q+S+FQAM+KGLI E RLLEAQ+ATGG
Sbjct: 2759 KEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGG 2818
Query: 1049 IIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRD 1105
+IDP H +P+ VA +RGY D+EM L+ S+ F P+ +Y QLLE C D
Sbjct: 2819 VIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVED 2878
Query: 1106 ETSGLHLLPLPESAPA--------LPTEEQVQRSLQAVPGAK---DGTSLWDLLSSCHFT 1154
+GL LLPL + A + +++ + P K ++W++++S +FT
Sbjct: 2879 PETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFT 2938
Query: 1155 EEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDAGII 1214
EQRR LL + GR TV +++ + V+E + + R+ G R VPA LL++ +I
Sbjct: 2939 AEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE--QKGRLCFEGLRSLVPAAELLESRVI 2996
Query: 1215 TQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTG 1274
+E + L +G +S VAE V+ L G +AGV L+ +G K SI A++ LLP+
Sbjct: 2997 DRELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSD 3056
Query: 1275 LGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRA 1334
+ LLEAQ +G ++DP + RL+V++AV+ GLVG E E+L AE+A GY DPY+
Sbjct: 3057 MAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQ 3116
Query: 1335 SLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLT 1394
S+SL+QA++KGL+P+ +GL LL QL+TGG+VDP +P AC G LD +TS+ L+
Sbjct: 3117 SVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALS 3176
Query: 1395 AVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMK 1454
A D K + DPS + TY +L++RC D TGL LLPL + L+A +
Sbjct: 3177 APRADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARE 3236
Query: 1455 ------VPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVTAL 1508
V V G FKG +V++W+L+ SEY A++R+EL+ R+G+ + + +T +
Sbjct: 3237 TFEKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIV 3296
Query: 1509 VEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
E + + +F GLR V A +L + ++SR ++L G TTVK+++E+ SV+ L+
Sbjct: 3297 EEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQ 3356
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G +AG+ ++ T+E++SI EA+RR +LR TA +LLEAQAATGF++DP N++L V EA
Sbjct: 3357 GSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEA 3416
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 1688
KAG+ G E + +LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATG
Sbjct: 3417 VKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATG 3476
Query: 1689 GIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVE 1748
GIIDPVHSHRVPVDVAY+ GYF EEMNR+LADPSDDTKGFFDPNTHENLTY QLLERCVE
Sbjct: 3477 GIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVE 3536
Query: 1749 DPETGLYLLQI--IKKGE----NYVYINEATRHVLQSRTAKM-RVGRFADQVVSFWDLLS 1801
DPETGL LL + +K E VY E TR + + G +S W+++
Sbjct: 3537 DPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQ 3596
Query: 1802 SPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETE-TQNQGI-KVAAIRGEVTAADL 1859
S E+++ +L+ ++ A E+++ II IE+TE + QG+ +R +TA DL
Sbjct: 3597 SDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDL 3656
Query: 1860 FNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRK 1919
F +R+I +T + LR G + E YL G+ +AGV +P +R+ +S+++A +K
Sbjct: 3657 FEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKK 3716
Query: 1920 ELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYR 1979
L+ A A LLEAQAATGFLLDP ++L+VDEAV GLV EL +RLL AERA TGYR
Sbjct: 3717 GLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYR 3776
Query: 1980 DPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKD 2039
DP T TI LFQAM+K+LI EALRLL+ Q+ATGG++DP+ LPLE AY+RG L+KD
Sbjct: 3777 DPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKD 3836
Query: 2040 IYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDET 2099
+ +S+ +R +VDP+T E++SY +L RCR + TG +L P++ A + +
Sbjct: 3837 THDQLSEPSEVRS-YVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT------- 3888
Query: 2100 RRALEAEQVEITVGRFRG--QKPTLWALLNSEYVTEEKKLQL------VRMYRTHTRRAL 2151
FRG ++ T+ L+ S+ + E LQL + + ++ L
Sbjct: 3889 ---------------FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFL 3933
Query: 2152 QTVAQLILELIE--KQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQE 2209
+ + + ++ K+ S +GI R TA ELL + T ++ ++ + T +E
Sbjct: 3934 EGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 3993
Query: 2210 LMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 2269
+ V + A V P + +S++QAM KG++ + LLEAQ AT
Sbjct: 3994 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4053
Query: 2270 GFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDL 2329
G +IDP + RL VE G+ E+ E L G+ DP T + ++ Q M++ +
Sbjct: 4054 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4113
Query: 2330 IVREHGIRLL-------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 2371
+ G+ LL E + ++ ++DP + V AYR+G D +
Sbjct: 4114 TDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4170
Score = 999 bits (2583), Expect = 0.0
Identities = 666/1843 (36%), Positives = 989/1843 (53%), Gaps = 126/1843 (6%)
Query: 234 TFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLL 293
+F + VSA L E GIL + +Q L +G +++ R +VR YL+G S+AG++L
Sbjct: 2649 SFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLK 2708
Query: 294 PEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELH 353
K S + A LL GTAL LLEAQAA+ L+DP+ +RL V+EAV+ G+V PELH
Sbjct: 2709 ATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELH 2768
Query: 354 EQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRL 413
+LL AE+AVTG+ DP++G QI LFQAM+KGL+ R +RLL+AQ+ATGG++ P R+
Sbjct: 2769 HKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRV 2828
Query: 414 PLEAALRCGCLDEDTQRQLSQA-----GSFSDGTHGGLRYEQLLALCVTDPETGLAFLPL 468
P++ A R G DE+ R L+ G F TH L Y QLL CV DPETGL LPL
Sbjct: 2829 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPL 2888
Query: 469 SG-GPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAML 527
+ +GGE + R AT + GKF+G+ V++WE++ SE ++EQR L
Sbjct: 2889 TDKAAKGGELV---YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDL 2945
Query: 528 AQQYQEGTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLE 587
+Q++ G ++VEK+ + +E+ R+ F GLR V ELL++ +ID++LY++L+
Sbjct: 2946 LRQFRTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQ 3005
Query: 588 HGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQ 647
G+ + +DV + + +R L+G IAG+ L + ++LSIY A K LL A+ LLEAQ
Sbjct: 3006 RGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQ 3065
Query: 648 AATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQ 707
A TG IIDP + +V+EA+RA ++GP+ KLLSAE+AVTGY DPYTGQ +SLFQA++
Sbjct: 3066 AGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALK 3125
Query: 708 KGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGF 767
KGLI RE G+RLL+AQ++TGG++DP SHRVP+DVA RG D+ + L P D K +
Sbjct: 3126 KGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAY 3185
Query: 768 FDPNTHENLTYLQLLERCVRDPETGLYLLPLS-----STQSPLV-DSATQQAFQNLLLSV 821
DP+T E TY +L +RC D TGL LLPLS + Q L + ++ F+ + V
Sbjct: 3186 SDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEV 3245
Query: 822 KYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQVAKLL-----EAETQRQA 876
G F+G+ V+ WELI+SEYF+ +R++LLR++R +VT+ +V K+L E ET RQ
Sbjct: 3246 PVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQE 3305
Query: 877 DIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVR 936
+ LR+ V +LL +G++ + +Q+ G + + L + VR L G G + G+
Sbjct: 3306 RLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIY 3365
Query: 937 LLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPE 996
L + +++S+Y+AMR+ LL A LLEAQAATG ++DP + L V EAV+ GVVGPE
Sbjct: 3366 LEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPE 3425
Query: 997 LYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHH 1056
L+ +L AE A+ G+RDP+SG +S+FQAM+KGL+ + RLLEAQ+ATGGIIDP H
Sbjct: 3426 LHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSH 3485
Query: 1057 HLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRDETSGLHLL 1113
+P+ VA QRGY +EM L+ S+ F P+ +Y QLLE C D +GL LL
Sbjct: 3486 RVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLL 3545
Query: 1114 PLPESAPA-------LPTEEQVQRSLQA----VPG----AKDGTSLWDLLSSCHFTEEQR 1158
PL + A + TEE+ +R+ + +PG SLW+++ S EEQR
Sbjct: 3546 PLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQR 3605
Query: 1159 RGLLEDVQEGRTTVPQLLASVQRWVQETKLL-AQARVMVPGPRGEVPAVWLLDAGIITQE 1217
L+ D Q GR T +++ + +++T+++ Q R + A L +A II+ E
Sbjct: 3606 AQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLE 3665
Query: 1218 TLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQ 1277
T L +GT+S + E + L+GTG VAGV L S SI QA++ GLL + +
Sbjct: 3666 TYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVAR 3725
Query: 1278 RLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLS 1337
LLEAQ A+GFL+DP+ +RL+V++AV+ GLVG EL ++L AERA GY DPY+ ++S
Sbjct: 3726 LLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTIS 3785
Query: 1338 LWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVD 1397
L+QAM+K L+P E L LL QLATGG+VDP G HLP A + G L+ T L+
Sbjct: 3786 LFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSE-P 3844
Query: 1398 KDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPV 1457
+ + + DPS ++++Y QL RC D TG LLLPL D + R ++ +
Sbjct: 3845 SEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPL--------SDARKLTFRGLRKQI 3896
Query: 1458 STGRFKGCSVSLWDLLLSEYVGADKRRELVALCR-SGRAAALRQVVSAVTALVEAAERQP 1516
+ V + E R L ++ + + S + + A ++
Sbjct: 3897 TMEELVRSQV------MDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKER 3950
Query: 1517 L---QATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSV-----KRSLE 1568
L QA +G+ + +A +L AQ + +D + TV+E M V + L
Sbjct: 3951 LSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLS 4010
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
+ G + + +S+ +A+++ ++ + LLEAQ ATG IIDP E+ +L VE A
Sbjct: 4011 AERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVA 4070
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL------- 1681
+K G+F +E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4071 YKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKR 4130
Query: 1682 EAQIATGG--------IIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNT 1733
E + ++ I+DP + V AYR G D +
Sbjct: 4131 ERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ-------------------- 4170
Query: 1734 HENLTYLQLLERCVEDPE------TGLYLLQIIKKGENYVY-INEATRHVLQSRTAKMRV 1786
TYL+L E+ E E G+ II + Y I++A L R+A +
Sbjct: 4171 ----TYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRSALDQY 4226
Query: 1787 GRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIK 1846
+ F D+LS R G+ S T ++ +
Sbjct: 4227 RAGTLSITEFADMLSG---NAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGP 4283
Query: 1847 VAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPS 1906
VA I T +V + +H V GQ L LE C G+ PS
Sbjct: 4284 VAGILDTETL-----EKVSITEAMHRNLVDNITGQRL---------LEAQACTGGIIDPS 4329
Query: 1907 TREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRE 1966
T E + +A K L+ + AQ A DP T+ K+S +A+ G + E +
Sbjct: 4330 TGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQ 4389
Query: 1967 RLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEV 2009
R L+ + G +P T +PL +A+Q+ ++ A +L +V
Sbjct: 4390 RFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV 4432
Score = 970 bits (2508), Expect = 0.0
Identities = 547/1287 (42%), Positives = 810/1287 (62%), Gaps = 33/1287 (2%)
Query: 1155 EEQRRGLL---EDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDA 1211
EEQ R L E+V + + L + + + A+ G R +V A L +A
Sbjct: 2606 EEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEA 2665
Query: 1212 GIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLL 1271
GI++ E L+ LAQG + ++A + V+ L G +AG+LL+ + K S+ A++ LL
Sbjct: 2666 GILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLL 2725
Query: 1272 PTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPY 1331
G LLEAQ ASGFL+DP+ N+RL+V +AVK G+VG EL +L AERA GY DPY
Sbjct: 2726 SPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPY 2785
Query: 1332 SRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQ 1391
+ +SL+QAM+KGL+ + G+ LL+ Q+ATGGV+DPVH +P A R G D + ++
Sbjct: 2786 TGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNR 2845
Query: 1392 VLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDT-----VLEVDDHT 1446
VL D K FFDP+ + +TY QL ERCV D ETGL LLPL ++ D
Sbjct: 2846 VLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEA 2905
Query: 1447 AVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVT 1506
V G+F+G +V++W+++ SEY A++RR+L+ R+GR + +++ +
Sbjct: 2906 RDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRIT-VEKIIKIII 2964
Query: 1507 ALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRS 1566
+VE E++ + F GLR V A +L +++I R+ +L +G +V++VAE+D+V+R+
Sbjct: 2965 TVVEEQEQKG-RLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 3023
Query: 1567 LEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVE 1626
L G N IAGV ++ +++SI AL++ +L A+ LLEAQA TG IIDPA + +LTV+
Sbjct: 3024 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVD 3083
Query: 1627 EAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIA 1686
EA +AG+ G E + KLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++
Sbjct: 3084 EAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLS 3143
Query: 1687 TGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERC 1746
TGGI+DP SHRVP+DVA G DEE +R L+ P D K + DP+T E TY +L +RC
Sbjct: 3144 TGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRC 3203
Query: 1747 VEDPETGLYLLQIIKKG----ENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSS 1802
D TGL LL + +K + +Y R + ++ VG F + V+ W+L+SS
Sbjct: 3204 RPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3263
Query: 1803 PYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQG-IKVAAIRGEVTAADLFN 1861
YFT ++++EL++++ +EK+++I+ T +EE ET Q + + +R V A++L
Sbjct: 3264 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3323
Query: 1862 SRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKEL 1921
S V+ + L+ G+T + LS L V+ L+GS C+AG+ + T+E +S++EA R+ L
Sbjct: 3324 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3383
Query: 1922 IPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDP 1981
+ A A LLEAQAATGFL+DP Q+L V EAV G+V EL E+LL AE+A TGYRDP
Sbjct: 3384 LRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDP 3443
Query: 1982 ATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIY 2041
+G TI LFQAMQK L+ + +RLLE Q+ATGG+IDP H HR+P++ AY+RG +++
Sbjct: 3444 YSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMN 3503
Query: 2042 ALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSE-------H 2094
+++D K F DPNT E ++YR+L ERC +TG L P+ K A +E +
Sbjct: 3504 RVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL-KGAEKAEVVETTQVY 3562
Query: 2095 IDDETRRALEAEQVEITVGRFRGQKP-TLWALLNSEYVTEEKKLQLVRMYRTHTRRALQT 2153
++ETRRA E Q++I G G +LW ++ S+ + EE++ QL+ ++ R +
Sbjct: 3563 TEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAG-RVTKER 3621
Query: 2154 VAQLILELIEKQETSNKH--LWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELM 2211
+ +I+E+IEK E + + +RR++TA +L + II+ E L G + +E +
Sbjct: 3622 MIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREAL 3681
Query: 2212 EDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGF 2271
E + YL GT +AGV +P G ++ +SIYQA+ KG+L A +LLEAQAATGF
Sbjct: 3682 EAESAWCYLYGTGSVAGVYLP-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGF 3736
Query: 2272 VIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIV 2331
++DPV+ RL+V+E V G+VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3737 LLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIP 3796
Query: 2332 REHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNT 2391
E +RLL+AQ+ATGG++DP +P++VAY+RGY +++ + L++PS + + + DP+T
Sbjct: 3797 TEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPST 3855
Query: 2392 HENLTYVQLLRRCVPDPDTGLYMLQLA 2418
E L+Y QLLRRC D TG +L L+
Sbjct: 3856 DERLSYTQLLRRCRRDDGTGQLLLPLS 3882
Score = 881 bits (2277), Expect = 0.0
Identities = 629/1746 (36%), Positives = 913/1746 (52%), Gaps = 133/1746 (7%)
Query: 41 RSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQ 100
R++ G +GQ S++ AM++GL+ G LLEAQ ATGG++D +PV A +
Sbjct: 2776 RAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR 2835
Query: 101 QGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEV--QLATG 158
+G E+ L T G+ DP E L Q + + V D G L + + A G
Sbjct: 2836 RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKG 2895
Query: 159 GLV----DPAQGVLVAPEPACHQGLLDRET---WHKLSELEPGTGDLR--FLNPNTLERL 209
G + A+ V + G +T W ++ E T + R L R+
Sbjct: 2896 GELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINS-EYFTAEQRRDLLRQFRTGRI 2954
Query: 210 TYHQLLERCVRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAV 269
T ++++ + ++ F + V AAELLE ++D + Q L+ G +
Sbjct: 2955 TVEKIIKIIITVVEEQEQ--KGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVR 3012
Query: 270 DVSARAEVRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLV 329
DV+ VRR L G +AGV L G K S + A + LLP A+ LLEAQA T ++
Sbjct: 3013 DVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHII 3072
Query: 330 DPITGQRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRP 389
DP T RL VDEAVRAGLV PE HE+LL AE+AVTG+ DP++G + LFQA+KKGL+ R
Sbjct: 3073 DPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPRE 3132
Query: 390 LALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLS----QAGSFSDGTHGG 445
LRLLDAQL+TGG+V P++ R+PL+ A GCLDE+T R LS A ++SD + G
Sbjct: 3133 QGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGE 3192
Query: 446 -LRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFR 504
Y +L C D TGL+ LPLS Q + + R+ V VG F+
Sbjct: 3193 PATYGELQQRCRPDQLTGLSLLPLSEKAARAR-QEELYSELQARETFEKTPVEVPVGGFK 3251
Query: 505 GRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAELSATLEQAAATA--RVTFSG 562
GR V++WEL+ SE ++EQR L +Q++ G ++VEK+ L +E+ R++FSG
Sbjct: 3252 GRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSG 3311
Query: 563 LRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQE 622
LR V ELL + ++ + +E+L+ G+ T KD+ L S + LQG+GC+AG+ L ++E
Sbjct: 3312 LRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKE 3371
Query: 623 RLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLL 682
++SIYEA +GLLR TA +LLEAQAATGF++DP N+ V EA++A V+GP++ +LL
Sbjct: 3372 KVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLL 3431
Query: 683 SAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDV 742
SAE+AVTGY DPY+G ISLFQAMQKGL++R+HGIRLLEAQIATGG+IDPVHSHRVPVDV
Sbjct: 3432 SAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3491
Query: 743 AYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQ 802
AY+RGYF + +N +L DPSDDTKGFFDPNTHENLTY QLLERCV DPETGL LLPL +
Sbjct: 3492 AYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAE 3551
Query: 803 SPLV--------DSATQQAFQNLLLSVK-YGRFQGQRVSAWELINSEYFSEGRRRQLLRR 853
V + T++AF+ + + G G +S WE++ S+ E +R QL+
Sbjct: 3552 KAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMAD 3611
Query: 854 YRQREVTLGQVAKLL-----EAETQRQADI-MLPALRSRVTVHQLLEAGIIDQQLLDQVL 907
++ VT ++ ++ + E RQ + +R R+T L EA II + + +
Sbjct: 3612 FQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLR 3671
Query: 908 AGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQ 967
GT S L + YL G G+V GV L S Q LS+YQA+++ LL VA LLEAQ
Sbjct: 3672 EGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQ 3731
Query: 968 AATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMK 1027
AATG ++DP E L+VDEAVR+G+VGPEL+ RL AE A+ G+RDP++ + +S+FQAMK
Sbjct: 3732 AATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMK 3791
Query: 1028 KGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSE--TFP 1085
K LIP E+A RLL+AQ+ATGGI+DP HLP+ VA QRGY++++ LS SE ++
Sbjct: 3792 KELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYV 3851
Query: 1086 TPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGTSLW 1145
P R SY QLL C RD+ +G LLPL ++ R L G + ++
Sbjct: 3852 DPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDA-----------RKL-TFRGLRKQITME 3899
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+ S E L +EG T++ ++ ++Q++++ T + A V V + +
Sbjct: 3900 ELVRSQVMDEATALQL----REGLTSIEEVTKNLQKFLEGTSCI--AGVFVDATKERLSV 3953
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAE---------QPAVKACLWG----------TG 1246
+ GII T L + + V + + AV+ + G
Sbjct: 3954 YQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAER 4013
Query: 1247 CVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKV 1306
V G SG S+ QA++ GL+ G RLLEAQ+A+G ++DP + RL VE A K
Sbjct: 4014 AVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKR 4073
Query: 1307 GLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLL---------- 1356
GL E++E L G+ DP + +L+ Q ME+ + GL LL
Sbjct: 4074 GLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERK 4133
Query: 1357 -----QVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQ 1411
V+ +VDP G + A R GL+D QT L+ + + ++
Sbjct: 4134 TSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECE---------WEE 4184
Query: 1412 VTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLW- 1470
+T D +++ S ++DD A L + +++ ++S+
Sbjct: 4185 ITISS------SDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRS---ALDQYRAGTLSITE 4235
Query: 1471 --DLLLSEYVGADKRRELVALCRS---GRAAALRQVVS---------AVTALVEAAERQP 1516
D+L G R V S A + Q+ S V +++ +
Sbjct: 4236 FADMLSGNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEK 4295
Query: 1517 L---QATFRGLRKQVSARDLFRAQ-----LISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
+ +A R L ++ + L AQ +I T + K + + V R
Sbjct: 4296 VSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINL 4355
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G T+ +MS +AL++ L LE Q TG +I+P ++ ++EA
Sbjct: 4356 AQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEA 4415
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-AT 1687
+ G T KL T P T +IS A+ + ++ G+RLLEA +T
Sbjct: 4416 LQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4475
Query: 1688 GGIIDP 1693
G P
Sbjct: 4476 KGYYSP 4481
Score = 869 bits (2246), Expect = 0.0
Identities = 711/2089 (34%), Positives = 1014/2089 (48%), Gaps = 390/2089 (18%)
Query: 2610 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 2665
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2538 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2597
Query: 2666 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 2712
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2598 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2654
Query: 2713 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 2772
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2655 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2711
Query: 2773 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 2832
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2712 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2769
Query: 2833 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2892
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2770 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2829
Query: 2893 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL- 2951
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L
Sbjct: 2830 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2889
Query: 2952 --AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRY 3009
A +G + E R A V+ G QG++V++WE++ + ++R+DLL ++
Sbjct: 2890 DKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQF 2949
Query: 3010 RAGTLTVEELGATLTSLLAQAQAQAR----------AEAEAGSPRPDPREALR------- 3052
R G +TVE++ + +++ + + + R AE R RE +
Sbjct: 2950 RTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGER 3009
Query: 3053 ----AATMEVKVGRLRGRAV--PVWDVLASGYVS--GAAREELL----------AEFGSG 3094
A ++ LRG V VW A +S A +++LL A+ G+G
Sbjct: 3010 SVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTG 3069
Query: 3095 TLDLPALTRRLTAIIEEAEEAPGARPQL--------------QDAWRG------------ 3128
+ PA + RLT ++EA A P+ +D + G
Sbjct: 3070 HIIDPATSARLT--VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKG 3127
Query: 3129 --PREPG-------PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQ 3168
PRE G + G D +S R G + ET A +A A A
Sbjct: 3128 LIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSD 3187
Query: 3169 EQTLRDATM-EVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLT 3227
T AT E+Q+ + + + S + AR++EL ++ A
Sbjct: 3188 PSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------R 3235
Query: 3228 RVIEETEERLSKVSFRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV----- 3278
E+T + F+G R V+ EL +S E LR G T+++V
Sbjct: 3236 ETFEKTPVEVPVGGFKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILI 3293
Query: 3279 TEMDSVKRYLEGTSCIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALV 3329
T ++ V+ + +G+ VPA + + E++ + K + G+
Sbjct: 3294 TIVEEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRT 3353
Query: 3330 LLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP-------- 3381
LL+ + ++S+ EA+ G++ LL A+ A DP
Sbjct: 3354 LLQGSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYV 3413
Query: 3382 ------------------------------YTGQQISLFQAMQKDLIVREHGIRLLEAQI 3411
Y+G ISLFQAMQK L++R+HGIRLLEAQI
Sbjct: 3414 HEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQI 3473
Query: 3412 ATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRR 3471
ATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL R
Sbjct: 3474 ATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLER 3533
Query: 3472 CVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWE 3524
CV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+WE
Sbjct: 3534 CVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWE 3593
Query: 3525 LLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA 3572
++ + E++R L++ ++AG +T E + + ++ + + + R A
Sbjct: 3594 VMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTA 3653
Query: 3573 ----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDV 3607
EA + LR T ++ G + G +P ++
Sbjct: 3654 EDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQA 3713
Query: 3608 LASGYVSG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREP 3666
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3714 LKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER- 3770
Query: 3667 GPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVW 3726
A G D Q + +E A R + L + R F P+ V
Sbjct: 3771 --AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV- 3826
Query: 3727 DVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------- 3772
YL++ D+ L + V + V T+ERLS
Sbjct: 3827 -AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGT 3874
Query: 3773 -----------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 3821
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++
Sbjct: 3875 GQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKF 3932
Query: 3822 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 3881
LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L
Sbjct: 3933 LEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGL 3987
Query: 3882 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 3941
+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLL
Sbjct: 3988 KLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLL 4047
Query: 3942 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQ 4001
EAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+Q
Sbjct: 4048 EAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQ 4107
Query: 4002 LLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLF 4061
L+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4108 LMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYEA-- 4161
Query: 4062 YREVSEDRRQDL-LSRYRA--STLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREA 4118
YR+ D + L LS +T+ + S++
Sbjct: 4162 YRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMI----------------------- 4198
Query: 4119 LRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIE 4178
+ R GR + D +A + R+A L ++ +GTL + L+
Sbjct: 4199 ---------IDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS---- 4241
Query: 4179 EAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ 4238
G++G + G + + A +R Q
Sbjct: 4242 -----------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLA 4272
Query: 4239 TLRDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDL 4290
+ D T E G G VS+ + + + + LL AQ G +
Sbjct: 4273 SWSDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI----- 4325
Query: 4291 VAVLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTL 4343
+ T ER ++ +GL ++ ++ + G P T ++
Sbjct: 4326 ------IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4379
Query: 4344 QEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQA 4403
+ ++ +R+LE G++ P D PGR + + +A+ +G + TA L + A
Sbjct: 4380 KGWLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGA 4434
Query: 4404 ATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 4451
+ ++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4435 YSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4483
Score = 852 bits (2202), Expect = 0.0
Identities = 715/2192 (32%), Positives = 1042/2192 (47%), Gaps = 408/2192 (18%)
Query: 1960 VNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEAL----RLLEVQVATGG 2015
+ +E + LK+E T ++ +T QA+Q+ + + ++L R +E + A
Sbjct: 2466 LQQEAKLLQLKSEEMQTVQQEQLLQET----QALQQSFLSEKDSLLQRERFIEQEKAKLE 2521
Query: 2016 VI---DPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERC 2072
+ + +L E ++ + ++ L++ + R+R + + ELQ+
Sbjct: 2522 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2581
Query: 2073 RPQEDTGWVLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVT 2132
+ + +L N+ R+ + +E RA A E+T + K
Sbjct: 2582 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL----------- 2630
Query: 2133 EEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSAII 2192
+ R AL A E +H F G+RR+++A L + I+
Sbjct: 2631 ------------PNGRDALDGPA---------AEAEPEHS-FDGLRRKVSAQRLQEAGIL 2668
Query: 2193 TEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKG 2252
+ E LQ L G +T EL + V+ YL+G S IAG+L+ A + EK+S+Y A+ +
Sbjct: 2669 SAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN-----EKLSVYAALQRQ 2723
Query: 2253 VLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTD 2312
+L PGTAL+LLEAQAA+GF++DPVRN RL+V E V GVVG E+ KLLSAERAVTGY D
Sbjct: 2724 LLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKD 2783
Query: 2313 PYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2372
PYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM
Sbjct: 2784 PYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2843
Query: 2373 NRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL---AGRGSAVHQLSE 2429
NRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L A +G +
Sbjct: 2844 NRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDS 2903
Query: 2430 ELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATL 2489
E R A V+ G QG++V++WE++ + ++R+DLL ++R G +TVE++ +
Sbjct: 2904 EARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKII 2963
Query: 2490 TSLLAQAQAQAR----------AEAEAGSPRPDPREALR-----------AATMEVKVGR 2528
+++ + + + R AE R RE + A ++
Sbjct: 2964 ITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 3023
Query: 2529 LRGRAV--PVWDVLASGYVS--RAAREELL----------AEFGSGTLDLPALTRRLTAI 2574
LRG V VW A +S A +++LL A+ G+G + PA + RLT
Sbjct: 3024 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLT-- 3081
Query: 2575 IEEAEEAPGARPQ--------------------------LQDARRG--PREPG------- 2599
++EA A P+ Q ++G PRE G
Sbjct: 3082 VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQ 3141
Query: 2600 PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQEQTLRDATM-EVQR 2647
+ G D +S R G + ET A +A A A T AT E+Q+
Sbjct: 3142 LSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQ 3201
Query: 2648 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVS 2707
+ + + S + AR++EL ++ A E+T +
Sbjct: 3202 RCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------RETFEKTPVEVPVGG 3249
Query: 2708 FRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV-----TEMDSVKRYLEGTS 2758
F+G R V+ EL +S E LR G T+++V T ++ V+ +
Sbjct: 3250 FKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERL 3307
Query: 2759 CIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDP 2809
+G+ VPA + + E++ + K + G+ LL+ +
Sbjct: 3308 SFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLE 3367
Query: 2810 VRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP---------------------- 2847
++S+ EA+ G++ LL A+ A DP
Sbjct: 3368 DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELH 3427
Query: 2848 ----------------YTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRV 2891
Y+G ISLFQAMQK L++R+HGIRLLEAQIATGG+IDPVHSHRV
Sbjct: 3428 EQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRV 3487
Query: 2892 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL 2951
PVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+TGL +L L
Sbjct: 3488 PVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL 3547
Query: 2952 AGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYREVSEDRRQD 3004
G A EE R A + ++ PG G+ G ++S+WE++ + E++R
Sbjct: 3548 KGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQ 3607
Query: 3005 LLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EAGSPRPDPR 3048
L++ ++AG +T E + + ++ + + + R A EA +
Sbjct: 3608 LMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETY 3667
Query: 3049 EALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYVSG-AAREE 3086
LR T ++ G + G +P ++ L G +S AR
Sbjct: 3668 NLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLL 3727
Query: 3087 LLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQ 3146
L A+ +G L P RLT ++EA P+L D A G D Q
Sbjct: 3728 LEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTGYRDPYTEQ 3782
Query: 3147 REGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRD 3206
+ +E A R + L + R F P+ V YL++ D
Sbjct: 3783 TISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRGYLNKDTHD 3839
Query: 3207 ELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------------KVS 3241
+ L + V + V T+ERLS K++
Sbjct: 3840 Q-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT 3888
Query: 3242 FRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPA 3301
FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSCIAGV V A
Sbjct: 3889 FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSCIAGVFVDA 3946
Query: 3302 KDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVG 3361
+E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEEAV G+VG
Sbjct: 3947 -----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVG 4001
Query: 3362 GEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVH 3421
E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIATGG+IDP
Sbjct: 4002 PEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEE 4061
Query: 3422 SHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLY 3481
SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+QL+ RC+ DP TGL
Sbjct: 4062 SHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLC 4121
Query: 3482 MLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLS 3541
+L L + S+ R V P + G+ +SV+E
Sbjct: 4122 LLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE----------------- 4160
Query: 3542 RYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRA 3601
YR G + + T L Q E S + + R GR
Sbjct: 4161 AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------DGVVKSMIIDRRSGRQ 4206
Query: 3602 VPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWR 3661
+ D +A + +A L ++ +GTL + L+
Sbjct: 4207 YDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS--------------------- 4241
Query: 3662 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG- 3720
G++G + G + + A +R Q + D T E G G
Sbjct: 4242 ------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEET--GPVAGI 4287
Query: 3721 ------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVAVLTRVIEETEER--L 3771
VS+ + + + + LL AQ G + + T ER +
Sbjct: 4288 LDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI-----------IDPSTGERFPV 4336
Query: 3772 SKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTS 3826
+ +GL ++ ++ + G P T ++ + ++ +R+LE
Sbjct: 4337 TDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQY 4396
Query: 3827 CIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVE 3886
G++ P D PGR + + +A+ +G + TA L + A + ++ P L++S +
Sbjct: 4397 LTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYK 4451
Query: 3887 EAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3917
+A+ +V +LL +A ++ GY PY+
Sbjct: 4452 DALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4483
Score = 727 bits (1876), Expect = 0.0
Identities = 710/2292 (30%), Positives = 1038/2292 (45%), Gaps = 316/2292 (13%)
Query: 3017 EELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLAS 3076
EE+ A S A +A E E G R + + LR+ + ++ R R + +
Sbjct: 1929 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE-QAELEAARQRQLAAEEERRR 1987
Query: 3077 GYVSGAAREELLAEFGSGTLDLPAL--TRRLTAIIEEAE------EAPGARPQLQDAWRG 3128
++ L AE + AL RL A +EEA E AR QLQ A
Sbjct: 1988 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEA 2046
Query: 3129 PREPGPAGRGDGDSGRSQREGQGEGETQEAAAA-------AAAARRQEQTLRDATMEVQR 3181
++ A Q+E + + Q+ + A AARR + +A ++ +R
Sbjct: 2047 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2106
Query: 3182 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAV-LTRVIEETEERLSKV 3240
Q R + EA R + A+ A A A L + E+ R ++
Sbjct: 2107 EAAQSR----------RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2156
Query: 3241 SFRGLR-RQVSASELHTSGILGPETLRDLAQGTKTLQ----EVTEMDSVKRYL-EGTSCI 3294
LR +Q + +E+ +TLR AQ + L ++ E D K L E +
Sbjct: 2157 EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRL 2216
Query: 3295 AGVLVPAKDQPGRQEK--------MSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 3346
A Q + E+ M + + AL+L + F+ +
Sbjct: 2217 KAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEK 2276
Query: 3347 LRLSVEEAVAAGVVGGE----------------------IQEKLLSAERAVTGYTDPYTG 3384
++ EEA V E ++EK+ + + A +
Sbjct: 2277 MKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2336
Query: 3385 QQ---ISLFQA---------MQKDLIVREHGI-RLLEA----QIATGGVIDPVHSHRVPV 3427
QQ ++ QA M + L G R LEA Q+ + + +
Sbjct: 2337 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2396
Query: 3428 DVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLL--RRCVPDPDTGLYMLQL 3485
A R D + R A+ + + T E +T VQ L +R D D +
Sbjct: 2397 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI 2456
Query: 3486 AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRA 3545
A +L +E + L + Q Q + + L +SE + LL R R
Sbjct: 2457 AELEREKEKLQQEAK--LLQLKSEEMQTVQQEQLLQETQALQQSFLSE--KDSLLQRERF 2512
Query: 3546 GTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPV- 3604
+L +A+AQ Q R E + + + A+ME R V
Sbjct: 2513 IEQEKAKLEQLFQDEVAKAQ-QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2571
Query: 3605 --WDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRG 3662
+ L +EELLAE + L +L + E+ A ++ +
Sbjct: 2572 RKQEELQQLEQQRRQQEELLAE------ENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2625
Query: 3663 PREPGPAGRG--DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG 3720
+ P GR DG + ++ E +G ++ +A R QE + A E+QR QG
Sbjct: 2626 ATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ----RLQEAGILSAE-ELQR-LAQG 2679
Query: 3721 RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 3780
+ E R E + + G + L+ ++ T E+LS + L+
Sbjct: 2680 HTT----------VDELARREDVRHYLQGRSSIAGLL------LKATNEKLSV--YAALQ 2721
Query: 3781 RQVSA---------SELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 3831
RQ+ + ++ + +L P R L + V + + L + G
Sbjct: 2722 RQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGY 2781
Query: 3832 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 3891
P Q ++S++QAM KG++ + LLEAQ ATG VIDPV + R+ V+ A
Sbjct: 2782 KDPYTGQ-----QISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRR 2836
Query: 3892 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEA--QIATGG 3949
G E+ L G+ DP T + ++ Q +++ + E G+ LL + A GG
Sbjct: 2837 GYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGG 2896
Query: 3950 VI--------DPVHSHRVPVDVAYRRG------------YFDEEMNRVLADPSDDTKGFF 3989
+ D V +G YF E R L +
Sbjct: 2897 ELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITV 2956
Query: 3990 DPNTHENLTYVQL-----------LRRCVPDP--------DTGLYMLQLAGRGSAVHQLS 4030
+ +T V+ LR VP D LY QL +V ++
Sbjct: 2957 EKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQ-QLQRGERSVRDVA 3015
Query: 4031 E--ELRCALRDARVTPGSGALQ-GQSVSVWELLFYREVSEDRRQDLLSRYRASTLTVEEL 4087
E +R ALR A V G + GQ +S++ L ++DLL A L +
Sbjct: 3016 EVDTVRRALRGANVIAGVWLEEAGQKLSIYNAL---------KKDLLPSDMAVALLEAQA 3066
Query: 4088 GAT-LTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGR--LRGRAVPVWDVLAS 4144
G + A+ AG P+ E L +A V R G++V ++ L
Sbjct: 3067 GTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKK 3126
Query: 4145 GYVSRAAREELL-AEFGSGTLDLPALTRRLTAII--------EEAEEAPGARPQLQDAWR 4195
G + R LL A+ +G + P+ + R+ + EE A A A+
Sbjct: 3127 GLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYS 3186
Query: 4196 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ---------TLRDATME 4246
P PA G+ + R Q G + + AA RQE+ T +E
Sbjct: 3187 DPSTGEPATYGELQ--QRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVE 3244
Query: 4247 VQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEE-RL 4305
V G F+GR V+VW+++ S Y + +R ELL Q G + + ++ +L ++EE E R
Sbjct: 3245 VPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQ 3304
Query: 4306 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 4365
++SF GLR V ASEL SG+L L G T+++++E+ SV+ L+G+ C+AG+
Sbjct: 3305 ERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGI 3364
Query: 4366 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 4425
+ +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL V EAV A
Sbjct: 3365 YLE-----DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKA 3419
Query: 4426 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 4485
GVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATGG+I
Sbjct: 3420 GVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGII 3479
Query: 4486 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 4545
DPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+
Sbjct: 3480 DPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPE 3539
Query: 4546 TGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYRE 4598
TGL +L L G A EE R A + ++ PG G+ G ++S+WE++
Sbjct: 3540 TGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDL 3599
Query: 4599 VSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EA 4642
+ E++R L++ ++AG +T E + + ++ + + + R A EA
Sbjct: 3600 IPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEA 3659
Query: 4643 GSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYV 4681
+ LR T ++ G + G +P ++ L G +
Sbjct: 3660 RIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLL 3719
Query: 4682 SG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRG 4740
S AR L A+ +G L P RLT ++EA P+L D A G
Sbjct: 3720 SAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTG 3774
Query: 4741 DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSS 4800
D Q + +E A R + L + R F P+ V
Sbjct: 3775 YRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRG 3831
Query: 4801 YLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------- 4840
YL++ D+ L + V + V T+ERLS
Sbjct: 3832 YLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLP 3880
Query: 4841 -----KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSC 4895
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSC
Sbjct: 3881 LSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSC 3938
Query: 4896 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 4955
IAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEE
Sbjct: 3939 IAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 3993
Query: 4956 AVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 5015
AV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIAT
Sbjct: 3994 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4053
Query: 5016 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRAT 5075
GG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTYLQL++R
Sbjct: 4054 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4113
Query: 5076 LDPETGLLFLSL 5087
DP+TGL L L
Sbjct: 4114 TDPQTGLCLLPL 4125
Score = 619 bits (1597), Expect = e-176
Identities = 476/1531 (31%), Positives = 736/1531 (48%), Gaps = 227/1531 (14%)
Query: 40 ARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKAL 99
A IAGV++E +GQ S+Y A+++ LLP+ + ALLEAQA TG ++D A L V +A+
Sbjct: 3027 ANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEAV 3086
Query: 100 QQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGG 159
+ GLVG E EKLL+AE+A TGY DPY G+ ++LFQA+ K ++ R G L+ QL+TGG
Sbjct: 3087 RAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTGG 3146
Query: 160 LVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCV 219
+VDP++ V + AC +G LD ET LS P + +P+T E TY +L +RC
Sbjct: 3147 IVDPSKSHRVPLDVACARGCLDEETSRALS--APRADAKAYSDPSTGEPATYGELQQRCR 3204
Query: 220 RAPGSGLALLPL------------------KITFRS----------MGGAVSAAELLEVG 251
+GL+LLPL + TF G V+ EL+
Sbjct: 3205 PDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISSE 3264
Query: 252 ILD-EQAVQGLREGRLAAV--------------DVSARAEVRRYLEGTGS--------VA 288
EQ + LR+ R V +V + R G + +
Sbjct: 3265 YFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLAS 3324
Query: 289 GVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAG-- 346
GV+ + + + + L +G+ LL+ + T +++ + EA+R G
Sbjct: 3325 GVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGLL 3384
Query: 347 -----------------LVSPELHEQLLVAE-------------------QAVTGHHDPF 370
LV P +++L V E +AVTG+ DP+
Sbjct: 3385 RATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDPY 3444
Query: 371 SGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQR 430
SGS I LFQAM+KGLV R +RLL+AQ+ATGG++ P R+P++ A + G E+ R
Sbjct: 3445 SGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMNR 3504
Query: 431 QLSQ-----AGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPP-FIK 484
L+ G F TH L Y QLL CV DPETGL LPL G + + + +
Sbjct: 3505 VLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVETTQVYTE 3564
Query: 485 YSTRQALSTATATV-SVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAA 543
TR+A + G G +SLWE++ S+ I EQRA L +Q G ++ E++
Sbjct: 3565 EETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMII 3624
Query: 544 ELSATLEQAAATAR---VTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLA 600
+ +E+ + ++ +R +T +L +A II + Y L G + ++
Sbjct: 3625 IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAE 3684
Query: 601 SAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANK 660
SA YL GTG +AG+ LPGS++ LSIY+A KGLL A +LLEAQAATGF++DP +
Sbjct: 3685 SAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGE 3744
Query: 661 GHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLL 720
+V+EA+R ++GP++ +LLSAERAVTGY DPYT Q ISLFQAM+K LI E +RLL
Sbjct: 3745 RLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLL 3804
Query: 721 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQ 780
+AQ+ATGG++DP +P++VAY+RGY ++ + L +PS + + + DP+T E L+Y Q
Sbjct: 3805 DAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQ 3863
Query: 781 LLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSE 840
LL RC RD TG LLPLS A + F+ L ++++ EL+ S+
Sbjct: 3864 LLRRCRRDDGTGQLLLPLS--------DARKLTFRGL----------RKQITMEELVRSQ 3905
Query: 841 YFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQ 900
E QL E + K LE T A + + A + R++V+Q ++ GII
Sbjct: 3906 VMDEATALQLREGLTSIEEVTKNLQKFLEG-TSCIAGVFVDATKERLSVYQAMKKGIIRP 3964
Query: 901 QLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVA 960
++L A G V G +L++ +A+R ++GP
Sbjct: 3965 GTAFELLEAQ-------------------AATGYVIDPIKGLKLTVEEAVRMGIVGPEFK 4005
Query: 961 LALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQV 1020
LL A+ A DP+S + +S+ +A+++G++ + RL A+ A G DP ++
Sbjct: 4006 DKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRL 4065
Query: 1021 SVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSS 1080
V A K+GL E L + T G DP + +L
Sbjct: 4066 PVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENL---------------------- 4103
Query: 1081 SETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPT--EEQVQRSLQAVPGA 1138
+Y QL+E C D +GL LLPL E T + V++ +
Sbjct: 4104 -------------TYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDP 4150
Query: 1139 KDGTSLWDLLSSCHFTEEQRRGLLE-----DVQEGRTTVPQLLASVQRWVQETKLLAQAR 1193
+ G + E R+GL++ ++ E ++ S V ++ ++ +
Sbjct: 4151 ETGKEM-------SVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRR- 4202
Query: 1194 VMVPGPRGEVPAVWLLDAGIITQETLEALAQGTQSPAQVAE------------------- 1234
G + ++ + +I + L+ GT S + A+
Sbjct: 4203 ---SGRQYDIDDA--IAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSS 4257
Query: 1235 -----QPAV---KACLWG-----TGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLE 1281
PAV + W TG VAG+L + K SI +A+ L+ GQRLLE
Sbjct: 4258 SSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLE 4317
Query: 1282 AQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQA 1341
AQ +G ++DP +R V DAV GLV + + +++ A++A G+ DP ++ +S QA
Sbjct: 4318 AQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQA 4377
Query: 1342 MEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNK 1401
++KG + G L+VQ TGG+++P +P A + G +D +T+Q L V +K
Sbjct: 4378 LKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSK 4437
Query: 1402 FFFDPSARDQVTYQQLRERCVCDSETGLLLL 1432
+ P + +++Y+ +R + + TGL LL
Sbjct: 4438 YLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4468
Score = 350 bits (897), Expect = 3e-95
Identities = 288/927 (31%), Positives = 451/927 (48%), Gaps = 110/927 (11%)
Query: 4243 ATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE 4302
AT+ G+FQG+ V++W+++ S Y + +R +LL Q G + + ++ ++ V+EE E
Sbjct: 2912 ATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE 2971
Query: 4303 ERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCI 4362
++ ++ F GLR V A+EL S ++ E + L +G +++++V E+D+V+R L G + I
Sbjct: 2972 QK-GRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRALRGANVI 3030
Query: 4363 AGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEA 4422
AGV + Q K+SIY A+ K +L A+ LLEAQA TG +IDP + RL+V+EA
Sbjct: 3031 AGVWLEEAGQ-----KLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEA 3085
Query: 4423 VAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 4482
V AG+VG E EKLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++TG
Sbjct: 3086 VRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTG 3145
Query: 4483 GVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVP 4542
G++DP SHRVP+DVA RG DEE +R L+ P D K + DP+T E TY +L +RC P
Sbjct: 3146 GIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRCRP 3205
Query: 4543 DPDTGLYMLQLAGRGSAVHQLSEELRCALRDARV---TPGS---GALQGQSVSVWELLFY 4596
D TGL +L L+ + + Q EEL L+ TP G +G++V+VWEL+
Sbjct: 3206 DQLTGLSLLPLSEKAARARQ--EELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3263
Query: 4597 REVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAE-AGSPRPDPREAL-- 4653
+ ++RQ+LL ++R G +TVE++ L +++ + + + +G P P L
Sbjct: 3264 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3323
Query: 4654 -----RAATMEVKVGR---------------LRGRA-------------VPVWDVLASGY 4680
RA ++K G+ L+G V +++ + G
Sbjct: 3324 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3383
Query: 4681 VSGAAREELL-AEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGR 4739
+ LL A+ +G L P +RL + EA +A P+L + E G
Sbjct: 3384 LRATTAALLLEAQAATGFLVDPVRNQRL--YVHEAVKAGVVGPELHEQLLSA-EKAVTGY 3440
Query: 4740 GDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQF----QGRPVSVWD 4795
D SG + Q A ++ +R ++ G V V
Sbjct: 3441 RDPYSGSTISLFQ---------AMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3491
Query: 4796 VLFSSYLSEARRDELLAQHAAGALGLPD--------LVAVLTRVIEETEERLSKVSFRGL 4847
Y SE + +LA + G D +L R +E+ E L + +G
Sbjct: 3492 AYQRGYFSE-EMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGA 3550
Query: 4848 RRQ--VSASELHTSGILG---PETLRDLAQG------TKTLQEVTEMDSVK--------- 4887
+ V ++++T ET D+ G T +L EV + D +
Sbjct: 3551 EKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMA 3610
Query: 4888 -----RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFV 4942
R + I + + K + RQ+ ++ Y V R TA L EA+ +
Sbjct: 3611 DFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDY----VRRRLTAEDLFEARIISLET 3666
Query: 4943 IDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 5002
+ +R S+ EA+ A E L +V G P + Q +S++QA++K L+
Sbjct: 3667 YNLLREGTRSLREALEA-----ESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSA 3721
Query: 5003 EHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTH 5062
E LLEAQ ATG ++DPV R+ VD A R+G E++ L G+ DP T
Sbjct: 3722 EVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTE 3781
Query: 5063 ENLTYLQLLQRATLDPETGLLFLSLSL 5089
+ ++ Q +++ + E L L L
Sbjct: 3782 QTISLFQAMKKELIPTEEALRLLDAQL 3808
Score = 347 bits (889), Expect = 2e-94
Identities = 202/360 (56%), Positives = 242/360 (67%), Gaps = 25/360 (6%)
Query: 4746 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 4801
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2538 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2597
Query: 4802 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 4848
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2598 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2654
Query: 4849 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 4908
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2655 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2711
Query: 4909 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 4968
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2712 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2769
Query: 4969 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 5028
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2770 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2829
Query: 5029 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLS 5088
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLL+R DPETGL L L+
Sbjct: 2830 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2889
Score = 254 bits (648), Expect = 2e-66
Identities = 137/307 (44%), Positives = 206/307 (67%), Gaps = 8/307 (2%)
Query: 4784 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE--ERLSK 4841
G G +S+W+V+ S + E +R +L+A AG + ++ ++ +IE+TE +
Sbjct: 3582 GSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGL 3641
Query: 4842 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 4901
S+ +RR+++A +L + I+ ET L +GT++L+E E +S YL GT +AGV +
Sbjct: 3642 ASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYL 3701
Query: 4902 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 4961
P G ++ +SIYQA+ KG+L A +LLEAQAATGF++DPV+ RL+V+EAV G+
Sbjct: 3702 P-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGL 3756
Query: 4962 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 5021
VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI E +RLL+AQ+ATGG++DP
Sbjct: 3757 VGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDP 3816
Query: 5022 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETG 5081
+P++VAY+RGY +++ + L++PS + + + DP+T E L+Y QLL+R D TG
Sbjct: 3817 RLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQLLRRCRRDDGTG 3875
Query: 5082 LLFLSLS 5088
L L LS
Sbjct: 3876 QLLLPLS 3882
Score = 107 bits (267), Expect = 3e-22
Identities = 73/212 (34%), Positives = 111/212 (52%), Gaps = 5/212 (2%)
Query: 4347 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4406
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4269 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4323
Query: 4407 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 4466
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4324 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4383
Query: 4467 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 4526
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4384 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4443
Query: 4527 THENLTYVQLLRRCVPDPDTGLYMLQLAGRGS 4558
T ++Y L R + + TGL +L+ A + +
Sbjct: 4444 TKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4475
Score = 107 bits (266), Expect = 4e-22
Identities = 73/210 (34%), Positives = 109/210 (51%), Gaps = 5/210 (2%)
Query: 4881 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4940
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4269 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4323
Query: 4941 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 5000
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4324 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4383
Query: 5001 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 5060
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4384 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4443
Query: 5061 THENLTYLQLLQRATLDPETGLLFLSLSLQ 5090
T ++Y L R+ ++ TGL L + Q
Sbjct: 4444 TKLKISYKDALDRSMVEEGTGLRLLEAAAQ 4473
Score = 105 bits (261), Expect = 2e-21
Identities = 69/217 (31%), Positives = 114/217 (52%), Gaps = 3/217 (1%)
Query: 13 GTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQ 72
G++S+ S P L + + P + +AG+ + + S+ AM + L+ GQ
Sbjct: 4255 GSSSSYPIS-PAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQ 4313
Query: 73 ALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLA 132
LLEAQA TGG++D + G+ PV+ A+ +GLV + +++ A++A G+ DP K++
Sbjct: 4314 RLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMS 4373
Query: 133 LFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLLDRETWHKLSELE 192
QA+ K + GQ +LEVQ TGGL++P V + A +G +D T KL ++
Sbjct: 4374 AAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV- 4432
Query: 193 PGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALL 229
G P T +++Y L+R + G+GL LL
Sbjct: 4433 -GAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4468
Score = 70.5 bits (171), Expect = 4e-11
Identities = 61/227 (26%), Positives = 102/227 (44%), Gaps = 17/227 (7%)
Query: 4832 IEETEERLS--KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 4889
++ T+ERLS + +G+ R +A EL + + + T++E M V
Sbjct: 3944 VDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPE 4003
Query: 4890 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 4949
+ A V P + +S++QAM KG++ + LLEAQ ATG +IDP +
Sbjct: 4004 FKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESH 4063
Query: 4950 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 5009
RL VE A G+ E+ E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4064 RLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLL 4123
Query: 5010 -------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 5041
E + ++ ++DP + V AYR+G D +
Sbjct: 4124 PLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4170
Score = 60.8 bits (146), Expect = 3e-08
Identities = 32/119 (26%), Positives = 61/119 (51%)
Query: 4971 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 5030
L ++ G T +++S++ A+Q+ L+ + LLEAQ A+G ++DPV + R+ V+
Sbjct: 2696 LQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVN 2755
Query: 5031 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSL 5089
A + G E++ L G+ DP T + ++ Q +Q+ + E G+ L +
Sbjct: 2756 EAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQI 2814
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4254 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4310
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4204 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4259
Query: 4311 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4359
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4260 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4319
Query: 4360 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4386
+C G++ P+ + P + KMS QA+
Sbjct: 4320 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4379
Query: 4387 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4446
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4380 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4439
Query: 4447 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 4487
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4440 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4481
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4788 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4844
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4204 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4259
Query: 4845 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4893
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4260 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4319
Query: 4894 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4920
+C G++ P+ + P + KMS QA+
Sbjct: 4320 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4379
Query: 4921 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4980
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4380 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4439
Query: 4981 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 5021
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4440 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4481
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 1268 bits (3280), Expect = 0.0
Identities = 798/1967 (40%), Positives = 1134/1967 (57%), Gaps = 218/1967 (11%)
Query: 1511 AAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLEGG 1570
AAE +P + +F GLR++VSA+ L A ++S + L L+QG TTV E+A + V+ L+G
Sbjct: 2637 AAEAEP-EHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGR 2695
Query: 1571 NFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFK 1630
+ IAG+L++ T E++S+ AL+R +L PGTAL+LLEAQAA+GF++DP NR+LTV EA K
Sbjct: 2696 SSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVK 2755
Query: 1631 AGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGI 1690
G+ G E + KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGG+
Sbjct: 2756 EGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGV 2815
Query: 1691 IDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 1750
IDPVHSHRVPVDVAYR GYFDEEMNR+LADPSDDTKGFFDPNTHENLTYLQLLERCVEDP
Sbjct: 2816 IDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 2875
Query: 1751 ETGLYLLQI---IKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTE 1807
ETGL LL + KG VY + R V + T G+F + V+ W++++S YFT
Sbjct: 2876 ETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTA 2935
Query: 1808 DRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLFNSRVIDQ 1867
+++R+L++++ +EK+++II T +EE E Q + +R V AA+L SRVID+
Sbjct: 2936 EQRRDLLRQFRTGRITVEKIIKIIITVVEEQE-QKGRLCFEGLRSLVPAAELLESRVIDR 2994
Query: 1868 KTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFA 1927
+ L+ G + ++ ++ V+ L G++ IAGV + + +S++ A +K+L+P+ A
Sbjct: 2995 ELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMA 3054
Query: 1928 TWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTI 1987
LLEAQA TG ++DP T +L+VDEAV GLV E E+LL AE+A TGYRDP TG ++
Sbjct: 3055 VALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSV 3114
Query: 1988 PLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQ 2047
LFQA++K LI + + LRLL+ Q++TGG++DP HR+PL+ A RGCL ++ +S
Sbjct: 3115 SLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAP 3174
Query: 2048 KHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVN-KAAR---DSEHIDDETRRAL 2103
+ K + DP+T E +Y ELQ+RCRP + TG L P++ KAAR + + + + R
Sbjct: 3175 RADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETF 3234
Query: 2104 EAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIE 2163
E VE+ VG F+G+ T+W L++SEY T E++ +L+R +RT + ++ V ++++ ++E
Sbjct: 3235 EKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRT-GKVTVEKVIKILITIVE 3293
Query: 2164 KQET-SNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEG 2222
+ ET + L F G+R + ASELL+S +++ + L+ G++T ++L E V+ L+G
Sbjct: 3294 EVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQG 3353
Query: 2223 TSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLS 2282
+ C+AG+ + +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL
Sbjct: 3354 SGCLAGIYL-----EDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLY 3408
Query: 2283 VEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQ 2342
V E V AGVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQ
Sbjct: 3409 VHEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQ 3468
Query: 2343 IATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLR 2402
IATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL
Sbjct: 3469 IATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLE 3528
Query: 2403 RCVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVW 2455
RCV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+W
Sbjct: 3529 RCVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLW 3588
Query: 2456 ELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAE 2503
E++ + E++R L++ ++AG +T E + + ++ + + + R
Sbjct: 3589 EVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLT 3648
Query: 2504 A----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWD 2538
A EA + LR T ++ G + G +P ++
Sbjct: 3649 AEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQ 3708
Query: 2539 VLASGYVS-RAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDARRGPRE 2597
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3709 ALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER 3766
Query: 2598 PGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSV 2657
A G D Q + +E A R + L + R F P+ V
Sbjct: 3767 ---AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV 3822
Query: 2658 WDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS------------- 2704
YL++ D+ L + V + V T+ERLS
Sbjct: 3823 --AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDG 3869
Query: 2705 ------------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKR 2752
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ ++++
Sbjct: 3870 TGQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQK 3927
Query: 2753 YLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 2812
+LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++
Sbjct: 3928 FLEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKG 3982
Query: 2813 LRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRL 2872
L+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRL
Sbjct: 3983 LKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRL 4042
Query: 2873 LEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYV 2932
LEAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+
Sbjct: 4043 LEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYL 4102
Query: 2933 QLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELL 2992
QL+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4103 QLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE-- 4156
Query: 2993 FYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALR 3052
YR G + + T L Q E S
Sbjct: 4157 ---------------AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------D 4187
Query: 3053 AATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEA 3112
+ + R GR + D +A + +A L ++ +GTL + L+
Sbjct: 4188 GVVKSMIIDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS------ 4237
Query: 3113 EEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTL 3172
G++G + G + + A +R Q +
Sbjct: 4238 ---------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASW 4270
Query: 3173 RDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVA 3224
D T E G G VS+ + + + + LL AQ G +
Sbjct: 4271 SDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI------- 4321
Query: 3225 VLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQE 3277
+ T ER ++ +GL ++ ++ + G P T ++ +
Sbjct: 4322 ----IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKG 4377
Query: 3278 VTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 3337
++ +R+LE G++ P D PGR + + +A+ +G + TA L + A +
Sbjct: 4378 WLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYS 4432
Query: 3338 GFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3383
++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4433 KYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4479
Score = 1127 bits (2914), Expect = 0.0
Identities = 724/1911 (37%), Positives = 1065/1911 (55%), Gaps = 110/1911 (5%)
Query: 522 EQRAMLAQQYQEGTLSVEKL-AAELSAT---------LEQAAATARV--TFSGLRDTVTP 569
EQ +L +Q++ E++ A++++AT L+ AA A +F GLR V+
Sbjct: 2596 EQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSA 2655
Query: 570 GELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEA 629
L +A I+ + +RL G T ++ + YLQG IAGLLL + E+LS+Y A
Sbjct: 2656 QRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAA 2715
Query: 630 RCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVT 689
+ LL PGTALILLEAQAA+GF++DP N+ +V EA++ V+GP++ KLLSAERAVT
Sbjct: 2716 LQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVT 2775
Query: 690 GYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 749
GY DPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF
Sbjct: 2776 GYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 2835
Query: 750 DQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSP----- 804
D+ +N +L DPSDDTKGFFDPNTHENLTYLQLLERCV DPETGL LLPL+ +
Sbjct: 2836 DEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELV 2895
Query: 805 LVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQV 864
DS + F+ +S +G+FQG+ V+ WE+INSEYF+ +RR LLR++R +T+ ++
Sbjct: 2896 YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKI 2955
Query: 865 AKLLEA---ETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDG 921
K++ E +++ + LRS V +LLE+ +ID++L Q+ G S + +D
Sbjct: 2956 IKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDT 3015
Query: 922 VRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPES 981
VRR L G + GV L +GQ+LS+Y A+++ LL +A+ALLEAQA TG I+DP +
Sbjct: 3016 VRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSAR 3075
Query: 982 LSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLE 1041
L+VDEAVR G+VGPE + +L AE A+ G+RDP++G+ VS+FQA+KKGLIP EQ RLL+
Sbjct: 3076 LTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLD 3135
Query: 1042 AQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSS---SSETFPTPDGQGRTSYAQL 1098
AQ++TGGI+DP+ H +P+ VA RG +D+E ALS+ ++ + P +Y +L
Sbjct: 3136 AQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGEL 3195
Query: 1099 LEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQA------------VPGAKDGT-SLW 1145
+ C D+ +GL LLPL E A A +E++ LQA V G K T ++W
Sbjct: 3196 QQRCRPDQLTGLSLLPLSEKA-ARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVW 3254
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+SS +FT EQR+ LL + G+ TV +++ + V+E + L Q R+ G R VPA
Sbjct: 3255 ELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPA 3314
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQA 1265
LL +G++++ E L G + ++E +V+ L G+GC+AG+ L+ + K SI +A
Sbjct: 3315 SELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEA 3374
Query: 1266 VRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAA 1325
+R GLL LLEAQ A+GFLVDP+ NQRL V +AVK G+VG EL EQL AE+A
Sbjct: 3375 MRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVT 3434
Query: 1326 GYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLL 1385
GY DPYS +++SL+QAM+KGLV + G+ LL+ Q+ATGG++DPVH +P A + G
Sbjct: 3435 GYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYF 3494
Query: 1386 DTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDH 1445
+ ++VL D K FFDP+ + +TY+QL ERCV D ETGL LLPL EV +
Sbjct: 3495 SEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVET 3554
Query: 1446 TAV--------ALRAMKVPV-STGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAA 1496
T V A ++ + G G ++SLW+++ S+ + ++R +L+A ++GR
Sbjct: 3555 TQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVT 3614
Query: 1497 ALRQVVSAVTALVEAAE--RQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTV 1554
R ++ + ++E E RQ A++ +R++++A DLF A++IS +T + L +GT ++
Sbjct: 3615 KERMII-IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSL 3673
Query: 1555 KEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFI 1614
+E E +S L G +AGV + G+++ +SI +AL++ +L A +LLEAQAATGF+
Sbjct: 3674 REALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFL 3733
Query: 1615 IDPAENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 1674
+DP + +LTV+EA + G+ G E + +LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3734 LDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPT 3793
Query: 1675 EHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTH 1734
E +RLL+AQ+ATGGI+DP +P++VAY+ GY +++ + L++PS+ + + DP+T
Sbjct: 3794 EEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSE-VRSYVDPSTD 3852
Query: 1735 ENLTYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVV 1794
E L+Y QLL RC D TG LL + A+ R + +
Sbjct: 3853 ERLSYTQLLRRCRRDDGTGQLLLPL--------------------SDARKLTFRGLRKQI 3892
Query: 1795 SFWDLLSSPYFTED---RKRELIQEYGAQSGGLEKLLE-------IITTTIEETETQNQG 1844
+ +L+ S E + RE + + L+K LE + +E + Q
Sbjct: 3893 TMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQA 3952
Query: 1845 IKVAAIRG----EVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIA 1900
+K IR E+ A VID L V + E L +
Sbjct: 3953 MKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVT 4012
Query: 1901 GVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLV 1960
G P + +++SL +A +K LI LLEAQ ATG ++DP +L V+ A GL
Sbjct: 4013 GYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLF 4072
Query: 1961 NEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLL------------- 2007
+EE+ E L G+ DP T + + Q M++ + + L LL
Sbjct: 4073 DEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSS 4132
Query: 2008 --EVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSY 2065
V+ ++DP+ + + AYR+G + Y +S+Q+ + ++ V
Sbjct: 4133 KSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKS 4192
Query: 2066 RELQERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALE----AEQVEITVGRFRGQKPT 2121
+ R Q D + + K D +D L A+ + G FR + +
Sbjct: 4193 MIIDRRSGRQYD---IDDAIAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSS 4249
Query: 2122 LWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQI 2181
+ + + + QL + T L E +EK S + + I
Sbjct: 4250 VGSSSSYPISPAVSRTQLA-SWSDPTEETGPVAGILDTETLEK--VSITEAMHRNLVDNI 4306
Query: 2182 TASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQE 2241
T LL + T ++ R + + V + + +A + P +
Sbjct: 4307 TGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKT 4366
Query: 2242 KMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLL 2301
KMS QA+ KG L LE Q TG +I+P R+ ++E + G V + +KL
Sbjct: 4367 KMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLR 4426
Query: 2302 SAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 2351
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4427 DVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4477
Score = 1054 bits (2725), Expect = 0.0
Identities = 630/1557 (40%), Positives = 924/1557 (59%), Gaps = 83/1557 (5%)
Query: 869 EAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCG 928
EAE + D LR +V+ +L EAGI+ + L ++ G + + L + VR YL G
Sbjct: 2639 EAEPEHSFD----GLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQG 2694
Query: 929 LGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAV 988
++ G+ L + ++LS+Y A++++LL P AL LLEAQAA+G ++DP L+V+EAV
Sbjct: 2695 RSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAV 2754
Query: 989 RRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGG 1048
+ GVVGPEL+ +L AE A+ G++DP++G+Q+S+FQAM+KGLI E RLLEAQ+ATGG
Sbjct: 2755 KEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGG 2814
Query: 1049 IIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRD 1105
+IDP H +P+ VA +RGY D+EM L+ S+ F P+ +Y QLLE C D
Sbjct: 2815 VIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVED 2874
Query: 1106 ETSGLHLLPLPESAPA--------LPTEEQVQRSLQAVPGAK---DGTSLWDLLSSCHFT 1154
+GL LLPL + A + +++ + P K ++W++++S +FT
Sbjct: 2875 PETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFT 2934
Query: 1155 EEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDAGII 1214
EQRR LL + GR TV +++ + V+E + + R+ G R VPA LL++ +I
Sbjct: 2935 AEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE--QKGRLCFEGLRSLVPAAELLESRVI 2992
Query: 1215 TQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTG 1274
+E + L +G +S VAE V+ L G +AGV L+ +G K SI A++ LLP+
Sbjct: 2993 DRELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSD 3052
Query: 1275 LGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRA 1334
+ LLEAQ +G ++DP + RL+V++AV+ GLVG E E+L AE+A GY DPY+
Sbjct: 3053 MAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQ 3112
Query: 1335 SLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLT 1394
S+SL+QA++KGL+P+ +GL LL QL+TGG+VDP +P AC G LD +TS+ L+
Sbjct: 3113 SVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALS 3172
Query: 1395 AVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMK 1454
A D K + DPS + TY +L++RC D TGL LLPL + L+A +
Sbjct: 3173 APRADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARE 3232
Query: 1455 ------VPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVTAL 1508
V V G FKG +V++W+L+ SEY A++R+EL+ R+G+ + + +T +
Sbjct: 3233 TFEKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIV 3292
Query: 1509 VEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
E + + +F GLR V A +L + ++SR ++L G TTVK+++E+ SV+ L+
Sbjct: 3293 EEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQ 3352
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G +AG+ ++ T+E++SI EA+RR +LR TA +LLEAQAATGF++DP N++L V EA
Sbjct: 3353 GSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEA 3412
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 1688
KAG+ G E + +LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATG
Sbjct: 3413 VKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATG 3472
Query: 1689 GIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVE 1748
GIIDPVHSHRVPVDVAY+ GYF EEMNR+LADPSDDTKGFFDPNTHENLTY QLLERCVE
Sbjct: 3473 GIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVE 3532
Query: 1749 DPETGLYLLQI--IKKGE----NYVYINEATRHVLQSRTAKM-RVGRFADQVVSFWDLLS 1801
DPETGL LL + +K E VY E TR + + G +S W+++
Sbjct: 3533 DPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQ 3592
Query: 1802 SPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETE-TQNQGI-KVAAIRGEVTAADL 1859
S E+++ +L+ ++ A E+++ II IE+TE + QG+ +R +TA DL
Sbjct: 3593 SDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDL 3652
Query: 1860 FNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRK 1919
F +R+I +T + LR G + E YL G+ +AGV +P +R+ +S+++A +K
Sbjct: 3653 FEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKK 3712
Query: 1920 ELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYR 1979
L+ A A LLEAQAATGFLLDP ++L+VDEAV GLV EL +RLL AERA TGYR
Sbjct: 3713 GLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYR 3772
Query: 1980 DPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKD 2039
DP T TI LFQAM+K+LI EALRLL+ Q+ATGG++DP+ LPLE AY+RG L+KD
Sbjct: 3773 DPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKD 3832
Query: 2040 IYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDET 2099
+ +S+ +R +VDP+T E++SY +L RCR + TG +L P++ A + +
Sbjct: 3833 THDQLSEPSEVRS-YVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT------- 3884
Query: 2100 RRALEAEQVEITVGRFRG--QKPTLWALLNSEYVTEEKKLQL------VRMYRTHTRRAL 2151
FRG ++ T+ L+ S+ + E LQL + + ++ L
Sbjct: 3885 ---------------FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFL 3929
Query: 2152 QTVAQLILELIE--KQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQE 2209
+ + + ++ K+ S +GI R TA ELL + T ++ ++ + T +E
Sbjct: 3930 EGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 3989
Query: 2210 LMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 2269
+ V + A V P + +S++QAM KG++ + LLEAQ AT
Sbjct: 3990 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4049
Query: 2270 GFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDL 2329
G +IDP + RL VE G+ E+ E L G+ DP T + ++ Q M++ +
Sbjct: 4050 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4109
Query: 2330 IVREHGIRLL-------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 2371
+ G+ LL E + ++ ++DP + V AYR+G D +
Sbjct: 4110 TDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4166
Score = 999 bits (2583), Expect = 0.0
Identities = 666/1843 (36%), Positives = 989/1843 (53%), Gaps = 126/1843 (6%)
Query: 234 TFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLL 293
+F + VSA L E GIL + +Q L +G +++ R +VR YL+G S+AG++L
Sbjct: 2645 SFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLK 2704
Query: 294 PEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELH 353
K S + A LL GTAL LLEAQAA+ L+DP+ +RL V+EAV+ G+V PELH
Sbjct: 2705 ATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELH 2764
Query: 354 EQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRL 413
+LL AE+AVTG+ DP++G QI LFQAM+KGL+ R +RLL+AQ+ATGG++ P R+
Sbjct: 2765 HKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRV 2824
Query: 414 PLEAALRCGCLDEDTQRQLSQA-----GSFSDGTHGGLRYEQLLALCVTDPETGLAFLPL 468
P++ A R G DE+ R L+ G F TH L Y QLL CV DPETGL LPL
Sbjct: 2825 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPL 2884
Query: 469 SG-GPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAML 527
+ +GGE + R AT + GKF+G+ V++WE++ SE ++EQR L
Sbjct: 2885 TDKAAKGGELV---YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDL 2941
Query: 528 AQQYQEGTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLE 587
+Q++ G ++VEK+ + +E+ R+ F GLR V ELL++ +ID++LY++L+
Sbjct: 2942 LRQFRTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQ 3001
Query: 588 HGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQ 647
G+ + +DV + + +R L+G IAG+ L + ++LSIY A K LL A+ LLEAQ
Sbjct: 3002 RGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQ 3061
Query: 648 AATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQ 707
A TG IIDP + +V+EA+RA ++GP+ KLLSAE+AVTGY DPYTGQ +SLFQA++
Sbjct: 3062 AGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALK 3121
Query: 708 KGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGF 767
KGLI RE G+RLL+AQ++TGG++DP SHRVP+DVA RG D+ + L P D K +
Sbjct: 3122 KGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAY 3181
Query: 768 FDPNTHENLTYLQLLERCVRDPETGLYLLPLS-----STQSPLV-DSATQQAFQNLLLSV 821
DP+T E TY +L +RC D TGL LLPLS + Q L + ++ F+ + V
Sbjct: 3182 SDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEV 3241
Query: 822 KYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQVAKLL-----EAETQRQA 876
G F+G+ V+ WELI+SEYF+ +R++LLR++R +VT+ +V K+L E ET RQ
Sbjct: 3242 PVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQE 3301
Query: 877 DIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVR 936
+ LR+ V +LL +G++ + +Q+ G + + L + VR L G G + G+
Sbjct: 3302 RLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIY 3361
Query: 937 LLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPE 996
L + +++S+Y+AMR+ LL A LLEAQAATG ++DP + L V EAV+ GVVGPE
Sbjct: 3362 LEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPE 3421
Query: 997 LYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHH 1056
L+ +L AE A+ G+RDP+SG +S+FQAM+KGL+ + RLLEAQ+ATGGIIDP H
Sbjct: 3422 LHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSH 3481
Query: 1057 HLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRDETSGLHLL 1113
+P+ VA QRGY +EM L+ S+ F P+ +Y QLLE C D +GL LL
Sbjct: 3482 RVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLL 3541
Query: 1114 PLPESAPA-------LPTEEQVQRSLQA----VPG----AKDGTSLWDLLSSCHFTEEQR 1158
PL + A + TEE+ +R+ + +PG SLW+++ S EEQR
Sbjct: 3542 PLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQR 3601
Query: 1159 RGLLEDVQEGRTTVPQLLASVQRWVQETKLL-AQARVMVPGPRGEVPAVWLLDAGIITQE 1217
L+ D Q GR T +++ + +++T+++ Q R + A L +A II+ E
Sbjct: 3602 AQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLE 3661
Query: 1218 TLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQ 1277
T L +GT+S + E + L+GTG VAGV L S SI QA++ GLL + +
Sbjct: 3662 TYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVAR 3721
Query: 1278 RLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLS 1337
LLEAQ A+GFL+DP+ +RL+V++AV+ GLVG EL ++L AERA GY DPY+ ++S
Sbjct: 3722 LLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTIS 3781
Query: 1338 LWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVD 1397
L+QAM+K L+P E L LL QLATGG+VDP G HLP A + G L+ T L+
Sbjct: 3782 LFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSE-P 3840
Query: 1398 KDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPV 1457
+ + + DPS ++++Y QL RC D TG LLLPL D + R ++ +
Sbjct: 3841 SEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPL--------SDARKLTFRGLRKQI 3892
Query: 1458 STGRFKGCSVSLWDLLLSEYVGADKRRELVALCR-SGRAAALRQVVSAVTALVEAAERQP 1516
+ V + E R L ++ + + S + + A ++
Sbjct: 3893 TMEELVRSQV------MDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKER 3946
Query: 1517 L---QATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSV-----KRSLE 1568
L QA +G+ + +A +L AQ + +D + TV+E M V + L
Sbjct: 3947 LSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLS 4006
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
+ G + + +S+ +A+++ ++ + LLEAQ ATG IIDP E+ +L VE A
Sbjct: 4007 AERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVA 4066
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL------- 1681
+K G+F +E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4067 YKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKR 4126
Query: 1682 EAQIATGG--------IIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNT 1733
E + ++ I+DP + V AYR G D +
Sbjct: 4127 ERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ-------------------- 4166
Query: 1734 HENLTYLQLLERCVEDPE------TGLYLLQIIKKGENYVY-INEATRHVLQSRTAKMRV 1786
TYL+L E+ E E G+ II + Y I++A L R+A +
Sbjct: 4167 ----TYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRSALDQY 4222
Query: 1787 GRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIK 1846
+ F D+LS R G+ S T ++ +
Sbjct: 4223 RAGTLSITEFADMLSG---NAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGP 4279
Query: 1847 VAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPS 1906
VA I T +V + +H V GQ L LE C G+ PS
Sbjct: 4280 VAGILDTETL-----EKVSITEAMHRNLVDNITGQRL---------LEAQACTGGIIDPS 4325
Query: 1907 TREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRE 1966
T E + +A K L+ + AQ A DP T+ K+S +A+ G + E +
Sbjct: 4326 TGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQ 4385
Query: 1967 RLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEV 2009
R L+ + G +P T +PL +A+Q+ ++ A +L +V
Sbjct: 4386 RFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV 4428
Score = 970 bits (2508), Expect = 0.0
Identities = 547/1287 (42%), Positives = 810/1287 (62%), Gaps = 33/1287 (2%)
Query: 1155 EEQRRGLL---EDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDA 1211
EEQ R L E+V + + L + + + A+ G R +V A L +A
Sbjct: 2602 EEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEA 2661
Query: 1212 GIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLL 1271
GI++ E L+ LAQG + ++A + V+ L G +AG+LL+ + K S+ A++ LL
Sbjct: 2662 GILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLL 2721
Query: 1272 PTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPY 1331
G LLEAQ ASGFL+DP+ N+RL+V +AVK G+VG EL +L AERA GY DPY
Sbjct: 2722 SPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPY 2781
Query: 1332 SRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQ 1391
+ +SL+QAM+KGL+ + G+ LL+ Q+ATGGV+DPVH +P A R G D + ++
Sbjct: 2782 TGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNR 2841
Query: 1392 VLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDT-----VLEVDDHT 1446
VL D K FFDP+ + +TY QL ERCV D ETGL LLPL ++ D
Sbjct: 2842 VLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEA 2901
Query: 1447 AVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVT 1506
V G+F+G +V++W+++ SEY A++RR+L+ R+GR + +++ +
Sbjct: 2902 RDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRIT-VEKIIKIII 2960
Query: 1507 ALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRS 1566
+VE E++ + F GLR V A +L +++I R+ +L +G +V++VAE+D+V+R+
Sbjct: 2961 TVVEEQEQKG-RLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 3019
Query: 1567 LEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVE 1626
L G N IAGV ++ +++SI AL++ +L A+ LLEAQA TG IIDPA + +LTV+
Sbjct: 3020 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVD 3079
Query: 1627 EAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIA 1686
EA +AG+ G E + KLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++
Sbjct: 3080 EAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLS 3139
Query: 1687 TGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERC 1746
TGGI+DP SHRVP+DVA G DEE +R L+ P D K + DP+T E TY +L +RC
Sbjct: 3140 TGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRC 3199
Query: 1747 VEDPETGLYLLQIIKKG----ENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSS 1802
D TGL LL + +K + +Y R + ++ VG F + V+ W+L+SS
Sbjct: 3200 RPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3259
Query: 1803 PYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQG-IKVAAIRGEVTAADLFN 1861
YFT ++++EL++++ +EK+++I+ T +EE ET Q + + +R V A++L
Sbjct: 3260 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3319
Query: 1862 SRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKEL 1921
S V+ + L+ G+T + LS L V+ L+GS C+AG+ + T+E +S++EA R+ L
Sbjct: 3320 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3379
Query: 1922 IPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDP 1981
+ A A LLEAQAATGFL+DP Q+L V EAV G+V EL E+LL AE+A TGYRDP
Sbjct: 3380 LRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDP 3439
Query: 1982 ATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIY 2041
+G TI LFQAMQK L+ + +RLLE Q+ATGG+IDP H HR+P++ AY+RG +++
Sbjct: 3440 YSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMN 3499
Query: 2042 ALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSE-------H 2094
+++D K F DPNT E ++YR+L ERC +TG L P+ K A +E +
Sbjct: 3500 RVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL-KGAEKAEVVETTQVY 3558
Query: 2095 IDDETRRALEAEQVEITVGRFRGQKP-TLWALLNSEYVTEEKKLQLVRMYRTHTRRALQT 2153
++ETRRA E Q++I G G +LW ++ S+ + EE++ QL+ ++ R +
Sbjct: 3559 TEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAG-RVTKER 3617
Query: 2154 VAQLILELIEKQETSNKH--LWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELM 2211
+ +I+E+IEK E + + +RR++TA +L + II+ E L G + +E +
Sbjct: 3618 MIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREAL 3677
Query: 2212 EDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGF 2271
E + YL GT +AGV +P G ++ +SIYQA+ KG+L A +LLEAQAATGF
Sbjct: 3678 EAESAWCYLYGTGSVAGVYLP-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGF 3732
Query: 2272 VIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIV 2331
++DPV+ RL+V+E V G+VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3733 LLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIP 3792
Query: 2332 REHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNT 2391
E +RLL+AQ+ATGG++DP +P++VAY+RGY +++ + L++PS + + + DP+T
Sbjct: 3793 TEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPST 3851
Query: 2392 HENLTYVQLLRRCVPDPDTGLYMLQLA 2418
E L+Y QLLRRC D TG +L L+
Sbjct: 3852 DERLSYTQLLRRCRRDDGTGQLLLPLS 3878
Score = 881 bits (2277), Expect = 0.0
Identities = 629/1746 (36%), Positives = 913/1746 (52%), Gaps = 133/1746 (7%)
Query: 41 RSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQ 100
R++ G +GQ S++ AM++GL+ G LLEAQ ATGG++D +PV A +
Sbjct: 2772 RAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR 2831
Query: 101 QGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEV--QLATG 158
+G E+ L T G+ DP E L Q + + V D G L + + A G
Sbjct: 2832 RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKG 2891
Query: 159 GLV----DPAQGVLVAPEPACHQGLLDRET---WHKLSELEPGTGDLR--FLNPNTLERL 209
G + A+ V + G +T W ++ E T + R L R+
Sbjct: 2892 GELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINS-EYFTAEQRRDLLRQFRTGRI 2950
Query: 210 TYHQLLERCVRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAV 269
T ++++ + ++ F + V AAELLE ++D + Q L+ G +
Sbjct: 2951 TVEKIIKIIITVVEEQEQ--KGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVR 3008
Query: 270 DVSARAEVRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLV 329
DV+ VRR L G +AGV L G K S + A + LLP A+ LLEAQA T ++
Sbjct: 3009 DVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHII 3068
Query: 330 DPITGQRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRP 389
DP T RL VDEAVRAGLV PE HE+LL AE+AVTG+ DP++G + LFQA+KKGL+ R
Sbjct: 3069 DPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPRE 3128
Query: 390 LALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLS----QAGSFSDGTHGG 445
LRLLDAQL+TGG+V P++ R+PL+ A GCLDE+T R LS A ++SD + G
Sbjct: 3129 QGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGE 3188
Query: 446 -LRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFR 504
Y +L C D TGL+ LPLS Q + + R+ V VG F+
Sbjct: 3189 PATYGELQQRCRPDQLTGLSLLPLSEKAARAR-QEELYSELQARETFEKTPVEVPVGGFK 3247
Query: 505 GRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAELSATLEQAAATA--RVTFSG 562
GR V++WEL+ SE ++EQR L +Q++ G ++VEK+ L +E+ R++FSG
Sbjct: 3248 GRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSG 3307
Query: 563 LRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQE 622
LR V ELL + ++ + +E+L+ G+ T KD+ L S + LQG+GC+AG+ L ++E
Sbjct: 3308 LRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKE 3367
Query: 623 RLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLL 682
++SIYEA +GLLR TA +LLEAQAATGF++DP N+ V EA++A V+GP++ +LL
Sbjct: 3368 KVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLL 3427
Query: 683 SAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDV 742
SAE+AVTGY DPY+G ISLFQAMQKGL++R+HGIRLLEAQIATGG+IDPVHSHRVPVDV
Sbjct: 3428 SAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3487
Query: 743 AYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQ 802
AY+RGYF + +N +L DPSDDTKGFFDPNTHENLTY QLLERCV DPETGL LLPL +
Sbjct: 3488 AYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAE 3547
Query: 803 SPLV--------DSATQQAFQNLLLSVK-YGRFQGQRVSAWELINSEYFSEGRRRQLLRR 853
V + T++AF+ + + G G +S WE++ S+ E +R QL+
Sbjct: 3548 KAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMAD 3607
Query: 854 YRQREVTLGQVAKLL-----EAETQRQADI-MLPALRSRVTVHQLLEAGIIDQQLLDQVL 907
++ VT ++ ++ + E RQ + +R R+T L EA II + + +
Sbjct: 3608 FQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLR 3667
Query: 908 AGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQ 967
GT S L + YL G G+V GV L S Q LS+YQA+++ LL VA LLEAQ
Sbjct: 3668 EGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQ 3727
Query: 968 AATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMK 1027
AATG ++DP E L+VDEAVR+G+VGPEL+ RL AE A+ G+RDP++ + +S+FQAMK
Sbjct: 3728 AATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMK 3787
Query: 1028 KGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSE--TFP 1085
K LIP E+A RLL+AQ+ATGGI+DP HLP+ VA QRGY++++ LS SE ++
Sbjct: 3788 KELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYV 3847
Query: 1086 TPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGTSLW 1145
P R SY QLL C RD+ +G LLPL ++ R L G + ++
Sbjct: 3848 DPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDA-----------RKL-TFRGLRKQITME 3895
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+ S E L +EG T++ ++ ++Q++++ T + A V V + +
Sbjct: 3896 ELVRSQVMDEATALQL----REGLTSIEEVTKNLQKFLEGTSCI--AGVFVDATKERLSV 3949
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAE---------QPAVKACLWG----------TG 1246
+ GII T L + + V + + AV+ + G
Sbjct: 3950 YQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAER 4009
Query: 1247 CVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKV 1306
V G SG S+ QA++ GL+ G RLLEAQ+A+G ++DP + RL VE A K
Sbjct: 4010 AVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKR 4069
Query: 1307 GLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLL---------- 1356
GL E++E L G+ DP + +L+ Q ME+ + GL LL
Sbjct: 4070 GLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERK 4129
Query: 1357 -----QVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQ 1411
V+ +VDP G + A R GL+D QT L+ + + ++
Sbjct: 4130 TSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECE---------WEE 4180
Query: 1412 VTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLW- 1470
+T D +++ S ++DD A L + +++ ++S+
Sbjct: 4181 ITISS------SDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRS---ALDQYRAGTLSITE 4231
Query: 1471 --DLLLSEYVGADKRRELVALCRS---GRAAALRQVVS---------AVTALVEAAERQP 1516
D+L G R V S A + Q+ S V +++ +
Sbjct: 4232 FADMLSGNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEK 4291
Query: 1517 L---QATFRGLRKQVSARDLFRAQ-----LISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
+ +A R L ++ + L AQ +I T + K + + V R
Sbjct: 4292 VSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINL 4351
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G T+ +MS +AL++ L LE Q TG +I+P ++ ++EA
Sbjct: 4352 AQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEA 4411
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-AT 1687
+ G T KL T P T +IS A+ + ++ G+RLLEA +T
Sbjct: 4412 LQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4471
Query: 1688 GGIIDP 1693
G P
Sbjct: 4472 KGYYSP 4477
Score = 869 bits (2246), Expect = 0.0
Identities = 711/2089 (34%), Positives = 1014/2089 (48%), Gaps = 390/2089 (18%)
Query: 2610 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 2665
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2534 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2593
Query: 2666 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 2712
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2594 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2650
Query: 2713 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 2772
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2651 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2707
Query: 2773 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 2832
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2708 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2765
Query: 2833 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2892
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2766 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2825
Query: 2893 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL- 2951
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L
Sbjct: 2826 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2885
Query: 2952 --AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRY 3009
A +G + E R A V+ G QG++V++WE++ + ++R+DLL ++
Sbjct: 2886 DKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQF 2945
Query: 3010 RAGTLTVEELGATLTSLLAQAQAQAR----------AEAEAGSPRPDPREALR------- 3052
R G +TVE++ + +++ + + + R AE R RE +
Sbjct: 2946 RTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGER 3005
Query: 3053 ----AATMEVKVGRLRGRAV--PVWDVLASGYVS--GAAREELL----------AEFGSG 3094
A ++ LRG V VW A +S A +++LL A+ G+G
Sbjct: 3006 SVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTG 3065
Query: 3095 TLDLPALTRRLTAIIEEAEEAPGARPQL--------------QDAWRG------------ 3128
+ PA + RLT ++EA A P+ +D + G
Sbjct: 3066 HIIDPATSARLT--VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKG 3123
Query: 3129 --PREPG-------PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQ 3168
PRE G + G D +S R G + ET A +A A A
Sbjct: 3124 LIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSD 3183
Query: 3169 EQTLRDATM-EVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLT 3227
T AT E+Q+ + + + S + AR++EL ++ A
Sbjct: 3184 PSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------R 3231
Query: 3228 RVIEETEERLSKVSFRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV----- 3278
E+T + F+G R V+ EL +S E LR G T+++V
Sbjct: 3232 ETFEKTPVEVPVGGFKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILI 3289
Query: 3279 TEMDSVKRYLEGTSCIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALV 3329
T ++ V+ + +G+ VPA + + E++ + K + G+
Sbjct: 3290 TIVEEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRT 3349
Query: 3330 LLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP-------- 3381
LL+ + ++S+ EA+ G++ LL A+ A DP
Sbjct: 3350 LLQGSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYV 3409
Query: 3382 ------------------------------YTGQQISLFQAMQKDLIVREHGIRLLEAQI 3411
Y+G ISLFQAMQK L++R+HGIRLLEAQI
Sbjct: 3410 HEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQI 3469
Query: 3412 ATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRR 3471
ATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL R
Sbjct: 3470 ATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLER 3529
Query: 3472 CVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWE 3524
CV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+WE
Sbjct: 3530 CVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWE 3589
Query: 3525 LLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA 3572
++ + E++R L++ ++AG +T E + + ++ + + + R A
Sbjct: 3590 VMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTA 3649
Query: 3573 ----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDV 3607
EA + LR T ++ G + G +P ++
Sbjct: 3650 EDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQA 3709
Query: 3608 LASGYVSG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREP 3666
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3710 LKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER- 3766
Query: 3667 GPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVW 3726
A G D Q + +E A R + L + R F P+ V
Sbjct: 3767 --AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV- 3822
Query: 3727 DVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------- 3772
YL++ D+ L + V + V T+ERLS
Sbjct: 3823 -AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGT 3870
Query: 3773 -----------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 3821
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++
Sbjct: 3871 GQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKF 3928
Query: 3822 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 3881
LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L
Sbjct: 3929 LEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGL 3983
Query: 3882 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 3941
+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLL
Sbjct: 3984 KLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLL 4043
Query: 3942 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQ 4001
EAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+Q
Sbjct: 4044 EAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQ 4103
Query: 4002 LLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLF 4061
L+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4104 LMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYEA-- 4157
Query: 4062 YREVSEDRRQDL-LSRYRA--STLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREA 4118
YR+ D + L LS +T+ + S++
Sbjct: 4158 YRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMI----------------------- 4194
Query: 4119 LRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIE 4178
+ R GR + D +A + R+A L ++ +GTL + L+
Sbjct: 4195 ---------IDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS---- 4237
Query: 4179 EAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ 4238
G++G + G + + A +R Q
Sbjct: 4238 -----------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLA 4268
Query: 4239 TLRDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDL 4290
+ D T E G G VS+ + + + + LL AQ G +
Sbjct: 4269 SWSDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI----- 4321
Query: 4291 VAVLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTL 4343
+ T ER ++ +GL ++ ++ + G P T ++
Sbjct: 4322 ------IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4375
Query: 4344 QEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQA 4403
+ ++ +R+LE G++ P D PGR + + +A+ +G + TA L + A
Sbjct: 4376 KGWLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGA 4430
Query: 4404 ATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 4451
+ ++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4431 YSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4479
Score = 852 bits (2202), Expect = 0.0
Identities = 715/2192 (32%), Positives = 1042/2192 (47%), Gaps = 408/2192 (18%)
Query: 1960 VNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEAL----RLLEVQVATGG 2015
+ +E + LK+E T ++ +T QA+Q+ + + ++L R +E + A
Sbjct: 2462 LQQEAKLLQLKSEEMQTVQQEQLLQET----QALQQSFLSEKDSLLQRERFIEQEKAKLE 2517
Query: 2016 VI---DPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERC 2072
+ + +L E ++ + ++ L++ + R+R + + ELQ+
Sbjct: 2518 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577
Query: 2073 RPQEDTGWVLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVT 2132
+ + +L N+ R+ + +E RA A E+T + K
Sbjct: 2578 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL----------- 2626
Query: 2133 EEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSAII 2192
+ R AL A E +H F G+RR+++A L + I+
Sbjct: 2627 ------------PNGRDALDGPA---------AEAEPEHS-FDGLRRKVSAQRLQEAGIL 2664
Query: 2193 TEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKG 2252
+ E LQ L G +T EL + V+ YL+G S IAG+L+ A + EK+S+Y A+ +
Sbjct: 2665 SAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN-----EKLSVYAALQRQ 2719
Query: 2253 VLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTD 2312
+L PGTAL+LLEAQAA+GF++DPVRN RL+V E V GVVG E+ KLLSAERAVTGY D
Sbjct: 2720 LLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKD 2779
Query: 2313 PYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2372
PYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM
Sbjct: 2780 PYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2839
Query: 2373 NRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL---AGRGSAVHQLSE 2429
NRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L A +G +
Sbjct: 2840 NRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDS 2899
Query: 2430 ELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATL 2489
E R A V+ G QG++V++WE++ + ++R+DLL ++R G +TVE++ +
Sbjct: 2900 EARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKII 2959
Query: 2490 TSLLAQAQAQAR----------AEAEAGSPRPDPREALR-----------AATMEVKVGR 2528
+++ + + + R AE R RE + A ++
Sbjct: 2960 ITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 3019
Query: 2529 LRGRAV--PVWDVLASGYVS--RAAREELL----------AEFGSGTLDLPALTRRLTAI 2574
LRG V VW A +S A +++LL A+ G+G + PA + RLT
Sbjct: 3020 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLT-- 3077
Query: 2575 IEEAEEAPGARPQ--------------------------LQDARRG--PREPG------- 2599
++EA A P+ Q ++G PRE G
Sbjct: 3078 VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQ 3137
Query: 2600 PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQEQTLRDATM-EVQR 2647
+ G D +S R G + ET A +A A A T AT E+Q+
Sbjct: 3138 LSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQ 3197
Query: 2648 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVS 2707
+ + + S + AR++EL ++ A E+T +
Sbjct: 3198 RCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------RETFEKTPVEVPVGG 3245
Query: 2708 FRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV-----TEMDSVKRYLEGTS 2758
F+G R V+ EL +S E LR G T+++V T ++ V+ +
Sbjct: 3246 FKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERL 3303
Query: 2759 CIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDP 2809
+G+ VPA + + E++ + K + G+ LL+ +
Sbjct: 3304 SFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLE 3363
Query: 2810 VRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP---------------------- 2847
++S+ EA+ G++ LL A+ A DP
Sbjct: 3364 DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELH 3423
Query: 2848 ----------------YTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRV 2891
Y+G ISLFQAMQK L++R+HGIRLLEAQIATGG+IDPVHSHRV
Sbjct: 3424 EQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRV 3483
Query: 2892 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL 2951
PVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+TGL +L L
Sbjct: 3484 PVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL 3543
Query: 2952 AGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYREVSEDRRQD 3004
G A EE R A + ++ PG G+ G ++S+WE++ + E++R
Sbjct: 3544 KGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQ 3603
Query: 3005 LLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EAGSPRPDPR 3048
L++ ++AG +T E + + ++ + + + R A EA +
Sbjct: 3604 LMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETY 3663
Query: 3049 EALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYVSG-AAREE 3086
LR T ++ G + G +P ++ L G +S AR
Sbjct: 3664 NLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLL 3723
Query: 3087 LLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQ 3146
L A+ +G L P RLT ++EA P+L D A G D Q
Sbjct: 3724 LEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTGYRDPYTEQ 3778
Query: 3147 REGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRD 3206
+ +E A R + L + R F P+ V YL++ D
Sbjct: 3779 TISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRGYLNKDTHD 3835
Query: 3207 ELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------------KVS 3241
+ L + V + V T+ERLS K++
Sbjct: 3836 Q-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT 3884
Query: 3242 FRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPA 3301
FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSCIAGV V A
Sbjct: 3885 FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSCIAGVFVDA 3942
Query: 3302 KDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVG 3361
+E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEEAV G+VG
Sbjct: 3943 -----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVG 3997
Query: 3362 GEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVH 3421
E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIATGG+IDP
Sbjct: 3998 PEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEE 4057
Query: 3422 SHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLY 3481
SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+QL+ RC+ DP TGL
Sbjct: 4058 SHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLC 4117
Query: 3482 MLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLS 3541
+L L + S+ R V P + G+ +SV+E
Sbjct: 4118 LLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE----------------- 4156
Query: 3542 RYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRA 3601
YR G + + T L Q E S + + R GR
Sbjct: 4157 AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------DGVVKSMIIDRRSGRQ 4202
Query: 3602 VPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWR 3661
+ D +A + +A L ++ +GTL + L+
Sbjct: 4203 YDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS--------------------- 4237
Query: 3662 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG- 3720
G++G + G + + A +R Q + D T E G G
Sbjct: 4238 ------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEET--GPVAGI 4283
Query: 3721 ------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVAVLTRVIEETEER--L 3771
VS+ + + + + LL AQ G + + T ER +
Sbjct: 4284 LDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI-----------IDPSTGERFPV 4332
Query: 3772 SKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTS 3826
+ +GL ++ ++ + G P T ++ + ++ +R+LE
Sbjct: 4333 TDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQY 4392
Query: 3827 CIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVE 3886
G++ P D PGR + + +A+ +G + TA L + A + ++ P L++S +
Sbjct: 4393 LTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYK 4447
Query: 3887 EAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3917
+A+ +V +LL +A ++ GY PY+
Sbjct: 4448 DALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4479
Score = 727 bits (1876), Expect = 0.0
Identities = 710/2292 (30%), Positives = 1038/2292 (45%), Gaps = 316/2292 (13%)
Query: 3017 EELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLAS 3076
EE+ A S A +A E E G R + + LR+ + ++ R R + +
Sbjct: 1925 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE-QAELEAARQRQLAAEEERRR 1983
Query: 3077 GYVSGAAREELLAEFGSGTLDLPAL--TRRLTAIIEEAE------EAPGARPQLQDAWRG 3128
++ L AE + AL RL A +EEA E AR QLQ A
Sbjct: 1984 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEA 2042
Query: 3129 PREPGPAGRGDGDSGRSQREGQGEGETQEAAAA-------AAAARRQEQTLRDATMEVQR 3181
++ A Q+E + + Q+ + A AARR + +A ++ +R
Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2102
Query: 3182 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAV-LTRVIEETEERLSKV 3240
Q R + EA R + A+ A A A L + E+ R ++
Sbjct: 2103 EAAQSR----------RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2152
Query: 3241 SFRGLR-RQVSASELHTSGILGPETLRDLAQGTKTLQ----EVTEMDSVKRYL-EGTSCI 3294
LR +Q + +E+ +TLR AQ + L ++ E D K L E +
Sbjct: 2153 EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRL 2212
Query: 3295 AGVLVPAKDQPGRQEK--------MSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 3346
A Q + E+ M + + AL+L + F+ +
Sbjct: 2213 KAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEK 2272
Query: 3347 LRLSVEEAVAAGVVGGE----------------------IQEKLLSAERAVTGYTDPYTG 3384
++ EEA V E ++EK+ + + A +
Sbjct: 2273 MKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2332
Query: 3385 QQ---ISLFQA---------MQKDLIVREHGI-RLLEA----QIATGGVIDPVHSHRVPV 3427
QQ ++ QA M + L G R LEA Q+ + + +
Sbjct: 2333 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2392
Query: 3428 DVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLL--RRCVPDPDTGLYMLQL 3485
A R D + R A+ + + T E +T VQ L +R D D +
Sbjct: 2393 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI 2452
Query: 3486 AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRA 3545
A +L +E + L + Q Q + + L +SE + LL R R
Sbjct: 2453 AELEREKEKLQQEAK--LLQLKSEEMQTVQQEQLLQETQALQQSFLSE--KDSLLQRERF 2508
Query: 3546 GTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPV- 3604
+L +A+AQ Q R E + + + A+ME R V
Sbjct: 2509 IEQEKAKLEQLFQDEVAKAQ-QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2567
Query: 3605 --WDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRG 3662
+ L +EELLAE + L +L + E+ A ++ +
Sbjct: 2568 RKQEELQQLEQQRRQQEELLAE------ENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2621
Query: 3663 PREPGPAGRG--DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG 3720
+ P GR DG + ++ E +G ++ +A R QE + A E+QR QG
Sbjct: 2622 ATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ----RLQEAGILSAE-ELQR-LAQG 2675
Query: 3721 RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 3780
+ E R E + + G + L+ ++ T E+LS + L+
Sbjct: 2676 HTT----------VDELARREDVRHYLQGRSSIAGLL------LKATNEKLSV--YAALQ 2717
Query: 3781 RQVSA---------SELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 3831
RQ+ + ++ + +L P R L + V + + L + G
Sbjct: 2718 RQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGY 2777
Query: 3832 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 3891
P Q ++S++QAM KG++ + LLEAQ ATG VIDPV + R+ V+ A
Sbjct: 2778 KDPYTGQ-----QISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRR 2832
Query: 3892 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEA--QIATGG 3949
G E+ L G+ DP T + ++ Q +++ + E G+ LL + A GG
Sbjct: 2833 GYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGG 2892
Query: 3950 VI--------DPVHSHRVPVDVAYRRG------------YFDEEMNRVLADPSDDTKGFF 3989
+ D V +G YF E R L +
Sbjct: 2893 ELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITV 2952
Query: 3990 DPNTHENLTYVQL-----------LRRCVPDP--------DTGLYMLQLAGRGSAVHQLS 4030
+ +T V+ LR VP D LY QL +V ++
Sbjct: 2953 EKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQ-QLQRGERSVRDVA 3011
Query: 4031 E--ELRCALRDARVTPGSGALQ-GQSVSVWELLFYREVSEDRRQDLLSRYRASTLTVEEL 4087
E +R ALR A V G + GQ +S++ L ++DLL A L +
Sbjct: 3012 EVDTVRRALRGANVIAGVWLEEAGQKLSIYNAL---------KKDLLPSDMAVALLEAQA 3062
Query: 4088 GAT-LTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGR--LRGRAVPVWDVLAS 4144
G + A+ AG P+ E L +A V R G++V ++ L
Sbjct: 3063 GTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKK 3122
Query: 4145 GYVSRAAREELL-AEFGSGTLDLPALTRRLTAII--------EEAEEAPGARPQLQDAWR 4195
G + R LL A+ +G + P+ + R+ + EE A A A+
Sbjct: 3123 GLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYS 3182
Query: 4196 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ---------TLRDATME 4246
P PA G+ + R Q G + + AA RQE+ T +E
Sbjct: 3183 DPSTGEPATYGELQ--QRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVE 3240
Query: 4247 VQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEE-RL 4305
V G F+GR V+VW+++ S Y + +R ELL Q G + + ++ +L ++EE E R
Sbjct: 3241 VPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQ 3300
Query: 4306 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 4365
++SF GLR V ASEL SG+L L G T+++++E+ SV+ L+G+ C+AG+
Sbjct: 3301 ERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGI 3360
Query: 4366 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 4425
+ +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL V EAV A
Sbjct: 3361 YLE-----DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKA 3415
Query: 4426 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 4485
GVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATGG+I
Sbjct: 3416 GVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGII 3475
Query: 4486 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 4545
DPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+
Sbjct: 3476 DPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPE 3535
Query: 4546 TGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYRE 4598
TGL +L L G A EE R A + ++ PG G+ G ++S+WE++
Sbjct: 3536 TGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDL 3595
Query: 4599 VSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EA 4642
+ E++R L++ ++AG +T E + + ++ + + + R A EA
Sbjct: 3596 IPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEA 3655
Query: 4643 GSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYV 4681
+ LR T ++ G + G +P ++ L G +
Sbjct: 3656 RIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLL 3715
Query: 4682 SG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRG 4740
S AR L A+ +G L P RLT ++EA P+L D A G
Sbjct: 3716 SAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTG 3770
Query: 4741 DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSS 4800
D Q + +E A R + L + R F P+ V
Sbjct: 3771 YRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRG 3827
Query: 4801 YLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------- 4840
YL++ D+ L + V + V T+ERLS
Sbjct: 3828 YLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLP 3876
Query: 4841 -----KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSC 4895
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSC
Sbjct: 3877 LSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSC 3934
Query: 4896 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 4955
IAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEE
Sbjct: 3935 IAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 3989
Query: 4956 AVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 5015
AV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIAT
Sbjct: 3990 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4049
Query: 5016 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRAT 5075
GG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTYLQL++R
Sbjct: 4050 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4109
Query: 5076 LDPETGLLFLSL 5087
DP+TGL L L
Sbjct: 4110 TDPQTGLCLLPL 4121
Score = 619 bits (1597), Expect = e-176
Identities = 476/1531 (31%), Positives = 736/1531 (48%), Gaps = 227/1531 (14%)
Query: 40 ARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKAL 99
A IAGV++E +GQ S+Y A+++ LLP+ + ALLEAQA TG ++D A L V +A+
Sbjct: 3023 ANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEAV 3082
Query: 100 QQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGG 159
+ GLVG E EKLL+AE+A TGY DPY G+ ++LFQA+ K ++ R G L+ QL+TGG
Sbjct: 3083 RAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTGG 3142
Query: 160 LVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCV 219
+VDP++ V + AC +G LD ET LS P + +P+T E TY +L +RC
Sbjct: 3143 IVDPSKSHRVPLDVACARGCLDEETSRALS--APRADAKAYSDPSTGEPATYGELQQRCR 3200
Query: 220 RAPGSGLALLPL------------------KITFRS----------MGGAVSAAELLEVG 251
+GL+LLPL + TF G V+ EL+
Sbjct: 3201 PDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISSE 3260
Query: 252 ILD-EQAVQGLREGRLAAV--------------DVSARAEVRRYLEGTGS--------VA 288
EQ + LR+ R V +V + R G + +
Sbjct: 3261 YFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLAS 3320
Query: 289 GVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAG-- 346
GV+ + + + + L +G+ LL+ + T +++ + EA+R G
Sbjct: 3321 GVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGLL 3380
Query: 347 -----------------LVSPELHEQLLVAE-------------------QAVTGHHDPF 370
LV P +++L V E +AVTG+ DP+
Sbjct: 3381 RATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDPY 3440
Query: 371 SGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQR 430
SGS I LFQAM+KGLV R +RLL+AQ+ATGG++ P R+P++ A + G E+ R
Sbjct: 3441 SGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMNR 3500
Query: 431 QLSQ-----AGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPP-FIK 484
L+ G F TH L Y QLL CV DPETGL LPL G + + + +
Sbjct: 3501 VLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVETTQVYTE 3560
Query: 485 YSTRQALSTATATV-SVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAA 543
TR+A + G G +SLWE++ S+ I EQRA L +Q G ++ E++
Sbjct: 3561 EETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMII 3620
Query: 544 ELSATLEQAAATAR---VTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLA 600
+ +E+ + ++ +R +T +L +A II + Y L G + ++
Sbjct: 3621 IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAE 3680
Query: 601 SAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANK 660
SA YL GTG +AG+ LPGS++ LSIY+A KGLL A +LLEAQAATGF++DP +
Sbjct: 3681 SAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGE 3740
Query: 661 GHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLL 720
+V+EA+R ++GP++ +LLSAERAVTGY DPYT Q ISLFQAM+K LI E +RLL
Sbjct: 3741 RLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLL 3800
Query: 721 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQ 780
+AQ+ATGG++DP +P++VAY+RGY ++ + L +PS + + + DP+T E L+Y Q
Sbjct: 3801 DAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQ 3859
Query: 781 LLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSE 840
LL RC RD TG LLPLS A + F+ L ++++ EL+ S+
Sbjct: 3860 LLRRCRRDDGTGQLLLPLS--------DARKLTFRGL----------RKQITMEELVRSQ 3901
Query: 841 YFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQ 900
E QL E + K LE T A + + A + R++V+Q ++ GII
Sbjct: 3902 VMDEATALQLREGLTSIEEVTKNLQKFLEG-TSCIAGVFVDATKERLSVYQAMKKGIIRP 3960
Query: 901 QLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVA 960
++L A G V G +L++ +A+R ++GP
Sbjct: 3961 GTAFELLEAQ-------------------AATGYVIDPIKGLKLTVEEAVRMGIVGPEFK 4001
Query: 961 LALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQV 1020
LL A+ A DP+S + +S+ +A+++G++ + RL A+ A G DP ++
Sbjct: 4002 DKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRL 4061
Query: 1021 SVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSS 1080
V A K+GL E L + T G DP + +L
Sbjct: 4062 PVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENL---------------------- 4099
Query: 1081 SETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPT--EEQVQRSLQAVPGA 1138
+Y QL+E C D +GL LLPL E T + V++ +
Sbjct: 4100 -------------TYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDP 4146
Query: 1139 KDGTSLWDLLSSCHFTEEQRRGLLE-----DVQEGRTTVPQLLASVQRWVQETKLLAQAR 1193
+ G + E R+GL++ ++ E ++ S V ++ ++ +
Sbjct: 4147 ETGKEM-------SVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRR- 4198
Query: 1194 VMVPGPRGEVPAVWLLDAGIITQETLEALAQGTQSPAQVAE------------------- 1234
G + ++ + +I + L+ GT S + A+
Sbjct: 4199 ---SGRQYDIDDA--IAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSS 4253
Query: 1235 -----QPAV---KACLWG-----TGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLE 1281
PAV + W TG VAG+L + K SI +A+ L+ GQRLLE
Sbjct: 4254 SSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLE 4313
Query: 1282 AQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQA 1341
AQ +G ++DP +R V DAV GLV + + +++ A++A G+ DP ++ +S QA
Sbjct: 4314 AQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQA 4373
Query: 1342 MEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNK 1401
++KG + G L+VQ TGG+++P +P A + G +D +T+Q L V +K
Sbjct: 4374 LKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSK 4433
Query: 1402 FFFDPSARDQVTYQQLRERCVCDSETGLLLL 1432
+ P + +++Y+ +R + + TGL LL
Sbjct: 4434 YLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4464
Score = 350 bits (897), Expect = 3e-95
Identities = 288/927 (31%), Positives = 451/927 (48%), Gaps = 110/927 (11%)
Query: 4243 ATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE 4302
AT+ G+FQG+ V++W+++ S Y + +R +LL Q G + + ++ ++ V+EE E
Sbjct: 2908 ATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE 2967
Query: 4303 ERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCI 4362
++ ++ F GLR V A+EL S ++ E + L +G +++++V E+D+V+R L G + I
Sbjct: 2968 QK-GRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRALRGANVI 3026
Query: 4363 AGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEA 4422
AGV + Q K+SIY A+ K +L A+ LLEAQA TG +IDP + RL+V+EA
Sbjct: 3027 AGVWLEEAGQ-----KLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEA 3081
Query: 4423 VAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 4482
V AG+VG E EKLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++TG
Sbjct: 3082 VRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTG 3141
Query: 4483 GVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVP 4542
G++DP SHRVP+DVA RG DEE +R L+ P D K + DP+T E TY +L +RC P
Sbjct: 3142 GIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRCRP 3201
Query: 4543 DPDTGLYMLQLAGRGSAVHQLSEELRCALRDARV---TPGS---GALQGQSVSVWELLFY 4596
D TGL +L L+ + + Q EEL L+ TP G +G++V+VWEL+
Sbjct: 3202 DQLTGLSLLPLSEKAARARQ--EELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3259
Query: 4597 REVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAE-AGSPRPDPREAL-- 4653
+ ++RQ+LL ++R G +TVE++ L +++ + + + +G P P L
Sbjct: 3260 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3319
Query: 4654 -----RAATMEVKVGR---------------LRGRA-------------VPVWDVLASGY 4680
RA ++K G+ L+G V +++ + G
Sbjct: 3320 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3379
Query: 4681 VSGAAREELL-AEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGR 4739
+ LL A+ +G L P +RL + EA +A P+L + E G
Sbjct: 3380 LRATTAALLLEAQAATGFLVDPVRNQRL--YVHEAVKAGVVGPELHEQLLSA-EKAVTGY 3436
Query: 4740 GDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQF----QGRPVSVWD 4795
D SG + Q A ++ +R ++ G V V
Sbjct: 3437 RDPYSGSTISLFQ---------AMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3487
Query: 4796 VLFSSYLSEARRDELLAQHAAGALGLPD--------LVAVLTRVIEETEERLSKVSFRGL 4847
Y SE + +LA + G D +L R +E+ E L + +G
Sbjct: 3488 AYQRGYFSE-EMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGA 3546
Query: 4848 RRQ--VSASELHTSGILG---PETLRDLAQG------TKTLQEVTEMDSVK--------- 4887
+ V ++++T ET D+ G T +L EV + D +
Sbjct: 3547 EKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMA 3606
Query: 4888 -----RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFV 4942
R + I + + K + RQ+ ++ Y V R TA L EA+ +
Sbjct: 3607 DFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDY----VRRRLTAEDLFEARIISLET 3662
Query: 4943 IDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 5002
+ +R S+ EA+ A E L +V G P + Q +S++QA++K L+
Sbjct: 3663 YNLLREGTRSLREALEA-----ESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSA 3717
Query: 5003 EHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTH 5062
E LLEAQ ATG ++DPV R+ VD A R+G E++ L G+ DP T
Sbjct: 3718 EVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTE 3777
Query: 5063 ENLTYLQLLQRATLDPETGLLFLSLSL 5089
+ ++ Q +++ + E L L L
Sbjct: 3778 QTISLFQAMKKELIPTEEALRLLDAQL 3804
Score = 347 bits (889), Expect = 2e-94
Identities = 202/360 (56%), Positives = 242/360 (67%), Gaps = 25/360 (6%)
Query: 4746 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 4801
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2534 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2593
Query: 4802 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 4848
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2594 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2650
Query: 4849 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 4908
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2651 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2707
Query: 4909 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 4968
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2708 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2765
Query: 4969 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 5028
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2766 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2825
Query: 5029 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLS 5088
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLL+R DPETGL L L+
Sbjct: 2826 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2885
Score = 254 bits (648), Expect = 2e-66
Identities = 137/307 (44%), Positives = 206/307 (67%), Gaps = 8/307 (2%)
Query: 4784 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE--ERLSK 4841
G G +S+W+V+ S + E +R +L+A AG + ++ ++ +IE+TE +
Sbjct: 3578 GSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGL 3637
Query: 4842 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 4901
S+ +RR+++A +L + I+ ET L +GT++L+E E +S YL GT +AGV +
Sbjct: 3638 ASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYL 3697
Query: 4902 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 4961
P G ++ +SIYQA+ KG+L A +LLEAQAATGF++DPV+ RL+V+EAV G+
Sbjct: 3698 P-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGL 3752
Query: 4962 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 5021
VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI E +RLL+AQ+ATGG++DP
Sbjct: 3753 VGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDP 3812
Query: 5022 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETG 5081
+P++VAY+RGY +++ + L++PS + + + DP+T E L+Y QLL+R D TG
Sbjct: 3813 RLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQLLRRCRRDDGTG 3871
Query: 5082 LLFLSLS 5088
L L LS
Sbjct: 3872 QLLLPLS 3878
Score = 107 bits (267), Expect = 3e-22
Identities = 73/212 (34%), Positives = 111/212 (52%), Gaps = 5/212 (2%)
Query: 4347 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4406
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4265 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4319
Query: 4407 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 4466
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4320 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4379
Query: 4467 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 4526
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4380 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4439
Query: 4527 THENLTYVQLLRRCVPDPDTGLYMLQLAGRGS 4558
T ++Y L R + + TGL +L+ A + +
Sbjct: 4440 TKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4471
Score = 107 bits (266), Expect = 4e-22
Identities = 73/210 (34%), Positives = 109/210 (51%), Gaps = 5/210 (2%)
Query: 4881 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4940
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4265 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4319
Query: 4941 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 5000
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4320 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4379
Query: 5001 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 5060
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4380 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4439
Query: 5061 THENLTYLQLLQRATLDPETGLLFLSLSLQ 5090
T ++Y L R+ ++ TGL L + Q
Sbjct: 4440 TKLKISYKDALDRSMVEEGTGLRLLEAAAQ 4469
Score = 105 bits (261), Expect = 2e-21
Identities = 69/217 (31%), Positives = 114/217 (52%), Gaps = 3/217 (1%)
Query: 13 GTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQ 72
G++S+ S P L + + P + +AG+ + + S+ AM + L+ GQ
Sbjct: 4251 GSSSSYPIS-PAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQ 4309
Query: 73 ALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLA 132
LLEAQA TGG++D + G+ PV+ A+ +GLV + +++ A++A G+ DP K++
Sbjct: 4310 RLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMS 4369
Query: 133 LFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLLDRETWHKLSELE 192
QA+ K + GQ +LEVQ TGGL++P V + A +G +D T KL ++
Sbjct: 4370 AAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV- 4428
Query: 193 PGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALL 229
G P T +++Y L+R + G+GL LL
Sbjct: 4429 -GAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4464
Score = 70.5 bits (171), Expect = 4e-11
Identities = 61/227 (26%), Positives = 102/227 (44%), Gaps = 17/227 (7%)
Query: 4832 IEETEERLS--KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 4889
++ T+ERLS + +G+ R +A EL + + + T++E M V
Sbjct: 3940 VDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPE 3999
Query: 4890 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 4949
+ A V P + +S++QAM KG++ + LLEAQ ATG +IDP +
Sbjct: 4000 FKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESH 4059
Query: 4950 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 5009
RL VE A G+ E+ E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4060 RLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLL 4119
Query: 5010 -------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 5041
E + ++ ++DP + V AYR+G D +
Sbjct: 4120 PLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4166
Score = 60.8 bits (146), Expect = 3e-08
Identities = 32/119 (26%), Positives = 61/119 (51%)
Query: 4971 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 5030
L ++ G T +++S++ A+Q+ L+ + LLEAQ A+G ++DPV + R+ V+
Sbjct: 2692 LQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVN 2751
Query: 5031 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSL 5089
A + G E++ L G+ DP T + ++ Q +Q+ + E G+ L +
Sbjct: 2752 EAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQI 2810
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4254 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4310
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4200 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4255
Query: 4311 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4359
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4256 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4315
Query: 4360 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4386
+C G++ P+ + P + KMS QA+
Sbjct: 4316 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4375
Query: 4387 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4446
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4376 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4435
Query: 4447 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 4487
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4436 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4477
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4788 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4844
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4200 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4255
Query: 4845 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4893
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4256 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4315
Query: 4894 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4920
+C G++ P+ + P + KMS QA+
Sbjct: 4316 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4375
Query: 4921 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4980
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4376 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4435
Query: 4981 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 5021
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4436 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4477
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 1268 bits (3280), Expect = 0.0
Identities = 798/1967 (40%), Positives = 1134/1967 (57%), Gaps = 218/1967 (11%)
Query: 1511 AAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLEGG 1570
AAE +P + +F GLR++VSA+ L A ++S + L L+QG TTV E+A + V+ L+G
Sbjct: 2605 AAEAEP-EHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGR 2663
Query: 1571 NFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFK 1630
+ IAG+L++ T E++S+ AL+R +L PGTAL+LLEAQAA+GF++DP NR+LTV EA K
Sbjct: 2664 SSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVK 2723
Query: 1631 AGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGI 1690
G+ G E + KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGG+
Sbjct: 2724 EGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGV 2783
Query: 1691 IDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 1750
IDPVHSHRVPVDVAYR GYFDEEMNR+LADPSDDTKGFFDPNTHENLTYLQLLERCVEDP
Sbjct: 2784 IDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 2843
Query: 1751 ETGLYLLQI---IKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTE 1807
ETGL LL + KG VY + R V + T G+F + V+ W++++S YFT
Sbjct: 2844 ETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTA 2903
Query: 1808 DRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLFNSRVIDQ 1867
+++R+L++++ +EK+++II T +EE E Q + +R V AA+L SRVID+
Sbjct: 2904 EQRRDLLRQFRTGRITVEKIIKIIITVVEEQE-QKGRLCFEGLRSLVPAAELLESRVIDR 2962
Query: 1868 KTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFA 1927
+ L+ G + ++ ++ V+ L G++ IAGV + + +S++ A +K+L+P+ A
Sbjct: 2963 ELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMA 3022
Query: 1928 TWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTI 1987
LLEAQA TG ++DP T +L+VDEAV GLV E E+LL AE+A TGYRDP TG ++
Sbjct: 3023 VALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSV 3082
Query: 1988 PLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQ 2047
LFQA++K LI + + LRLL+ Q++TGG++DP HR+PL+ A RGCL ++ +S
Sbjct: 3083 SLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAP 3142
Query: 2048 KHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVN-KAAR---DSEHIDDETRRAL 2103
+ K + DP+T E +Y ELQ+RCRP + TG L P++ KAAR + + + + R
Sbjct: 3143 RADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETF 3202
Query: 2104 EAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIE 2163
E VE+ VG F+G+ T+W L++SEY T E++ +L+R +RT + ++ V ++++ ++E
Sbjct: 3203 EKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRT-GKVTVEKVIKILITIVE 3261
Query: 2164 KQET-SNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEG 2222
+ ET + L F G+R + ASELL+S +++ + L+ G++T ++L E V+ L+G
Sbjct: 3262 EVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQG 3321
Query: 2223 TSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLS 2282
+ C+AG+ + +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL
Sbjct: 3322 SGCLAGIYL-----EDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLY 3376
Query: 2283 VEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQ 2342
V E V AGVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQ
Sbjct: 3377 VHEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQ 3436
Query: 2343 IATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLR 2402
IATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL
Sbjct: 3437 IATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLE 3496
Query: 2403 RCVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVW 2455
RCV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+W
Sbjct: 3497 RCVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLW 3556
Query: 2456 ELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAE 2503
E++ + E++R L++ ++AG +T E + + ++ + + + R
Sbjct: 3557 EVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLT 3616
Query: 2504 A----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWD 2538
A EA + LR T ++ G + G +P ++
Sbjct: 3617 AEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQ 3676
Query: 2539 VLASGYVS-RAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDARRGPRE 2597
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3677 ALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER 3734
Query: 2598 PGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSV 2657
A G D Q + +E A R + L + R F P+ V
Sbjct: 3735 ---AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV 3790
Query: 2658 WDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS------------- 2704
YL++ D+ L + V + V T+ERLS
Sbjct: 3791 --AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDG 3837
Query: 2705 ------------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKR 2752
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ ++++
Sbjct: 3838 TGQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQK 3895
Query: 2753 YLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 2812
+LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++
Sbjct: 3896 FLEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKG 3950
Query: 2813 LRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRL 2872
L+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRL
Sbjct: 3951 LKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRL 4010
Query: 2873 LEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYV 2932
LEAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+
Sbjct: 4011 LEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYL 4070
Query: 2933 QLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELL 2992
QL+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4071 QLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE-- 4124
Query: 2993 FYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALR 3052
YR G + + T L Q E S
Sbjct: 4125 ---------------AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------D 4155
Query: 3053 AATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEA 3112
+ + R GR + D +A + +A L ++ +GTL + L+
Sbjct: 4156 GVVKSMIIDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS------ 4205
Query: 3113 EEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTL 3172
G++G + G + + A +R Q +
Sbjct: 4206 ---------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASW 4238
Query: 3173 RDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVA 3224
D T E G G VS+ + + + + LL AQ G +
Sbjct: 4239 SDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI------- 4289
Query: 3225 VLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQE 3277
+ T ER ++ +GL ++ ++ + G P T ++ +
Sbjct: 4290 ----IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKG 4345
Query: 3278 VTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 3337
++ +R+LE G++ P D PGR + + +A+ +G + TA L + A +
Sbjct: 4346 WLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYS 4400
Query: 3338 GFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3383
++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4401 KYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4447
Score = 1127 bits (2914), Expect = 0.0
Identities = 724/1911 (37%), Positives = 1065/1911 (55%), Gaps = 110/1911 (5%)
Query: 522 EQRAMLAQQYQEGTLSVEKL-AAELSAT---------LEQAAATARV--TFSGLRDTVTP 569
EQ +L +Q++ E++ A++++AT L+ AA A +F GLR V+
Sbjct: 2564 EQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSA 2623
Query: 570 GELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEA 629
L +A I+ + +RL G T ++ + YLQG IAGLLL + E+LS+Y A
Sbjct: 2624 QRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAA 2683
Query: 630 RCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVT 689
+ LL PGTALILLEAQAA+GF++DP N+ +V EA++ V+GP++ KLLSAERAVT
Sbjct: 2684 LQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVT 2743
Query: 690 GYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 749
GY DPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF
Sbjct: 2744 GYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 2803
Query: 750 DQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSP----- 804
D+ +N +L DPSDDTKGFFDPNTHENLTYLQLLERCV DPETGL LLPL+ +
Sbjct: 2804 DEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELV 2863
Query: 805 LVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQV 864
DS + F+ +S +G+FQG+ V+ WE+INSEYF+ +RR LLR++R +T+ ++
Sbjct: 2864 YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKI 2923
Query: 865 AKLLEA---ETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDG 921
K++ E +++ + LRS V +LLE+ +ID++L Q+ G S + +D
Sbjct: 2924 IKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDT 2983
Query: 922 VRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPES 981
VRR L G + GV L +GQ+LS+Y A+++ LL +A+ALLEAQA TG I+DP +
Sbjct: 2984 VRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSAR 3043
Query: 982 LSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLE 1041
L+VDEAVR G+VGPE + +L AE A+ G+RDP++G+ VS+FQA+KKGLIP EQ RLL+
Sbjct: 3044 LTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLD 3103
Query: 1042 AQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSS---SSETFPTPDGQGRTSYAQL 1098
AQ++TGGI+DP+ H +P+ VA RG +D+E ALS+ ++ + P +Y +L
Sbjct: 3104 AQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGEL 3163
Query: 1099 LEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQA------------VPGAKDGT-SLW 1145
+ C D+ +GL LLPL E A A +E++ LQA V G K T ++W
Sbjct: 3164 QQRCRPDQLTGLSLLPLSEKA-ARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVW 3222
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+SS +FT EQR+ LL + G+ TV +++ + V+E + L Q R+ G R VPA
Sbjct: 3223 ELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPA 3282
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQA 1265
LL +G++++ E L G + ++E +V+ L G+GC+AG+ L+ + K SI +A
Sbjct: 3283 SELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEA 3342
Query: 1266 VRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAA 1325
+R GLL LLEAQ A+GFLVDP+ NQRL V +AVK G+VG EL EQL AE+A
Sbjct: 3343 MRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVT 3402
Query: 1326 GYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLL 1385
GY DPYS +++SL+QAM+KGLV + G+ LL+ Q+ATGG++DPVH +P A + G
Sbjct: 3403 GYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYF 3462
Query: 1386 DTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDH 1445
+ ++VL D K FFDP+ + +TY+QL ERCV D ETGL LLPL EV +
Sbjct: 3463 SEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVET 3522
Query: 1446 TAV--------ALRAMKVPV-STGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAA 1496
T V A ++ + G G ++SLW+++ S+ + ++R +L+A ++GR
Sbjct: 3523 TQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVT 3582
Query: 1497 ALRQVVSAVTALVEAAE--RQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTV 1554
R ++ + ++E E RQ A++ +R++++A DLF A++IS +T + L +GT ++
Sbjct: 3583 KERMII-IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSL 3641
Query: 1555 KEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFI 1614
+E E +S L G +AGV + G+++ +SI +AL++ +L A +LLEAQAATGF+
Sbjct: 3642 REALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFL 3701
Query: 1615 IDPAENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 1674
+DP + +LTV+EA + G+ G E + +LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3702 LDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPT 3761
Query: 1675 EHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTH 1734
E +RLL+AQ+ATGGI+DP +P++VAY+ GY +++ + L++PS+ + + DP+T
Sbjct: 3762 EEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSE-VRSYVDPSTD 3820
Query: 1735 ENLTYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVV 1794
E L+Y QLL RC D TG LL + A+ R + +
Sbjct: 3821 ERLSYTQLLRRCRRDDGTGQLLLPL--------------------SDARKLTFRGLRKQI 3860
Query: 1795 SFWDLLSSPYFTED---RKRELIQEYGAQSGGLEKLLE-------IITTTIEETETQNQG 1844
+ +L+ S E + RE + + L+K LE + +E + Q
Sbjct: 3861 TMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQA 3920
Query: 1845 IKVAAIRG----EVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIA 1900
+K IR E+ A VID L V + E L +
Sbjct: 3921 MKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVT 3980
Query: 1901 GVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLV 1960
G P + +++SL +A +K LI LLEAQ ATG ++DP +L V+ A GL
Sbjct: 3981 GYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLF 4040
Query: 1961 NEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLL------------- 2007
+EE+ E L G+ DP T + + Q M++ + + L LL
Sbjct: 4041 DEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSS 4100
Query: 2008 --EVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSY 2065
V+ ++DP+ + + AYR+G + Y +S+Q+ + ++ V
Sbjct: 4101 KSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKS 4160
Query: 2066 RELQERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALE----AEQVEITVGRFRGQKPT 2121
+ R Q D + + K D +D L A+ + G FR + +
Sbjct: 4161 MIIDRRSGRQYD---IDDAIAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSS 4217
Query: 2122 LWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQI 2181
+ + + + QL + T L E +EK S + + I
Sbjct: 4218 VGSSSSYPISPAVSRTQLA-SWSDPTEETGPVAGILDTETLEK--VSITEAMHRNLVDNI 4274
Query: 2182 TASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQE 2241
T LL + T ++ R + + V + + +A + P +
Sbjct: 4275 TGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKT 4334
Query: 2242 KMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLL 2301
KMS QA+ KG L LE Q TG +I+P R+ ++E + G V + +KL
Sbjct: 4335 KMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLR 4394
Query: 2302 SAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 2351
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4395 DVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4445
Score = 1054 bits (2725), Expect = 0.0
Identities = 630/1557 (40%), Positives = 924/1557 (59%), Gaps = 83/1557 (5%)
Query: 869 EAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCG 928
EAE + D LR +V+ +L EAGI+ + L ++ G + + L + VR YL G
Sbjct: 2607 EAEPEHSFD----GLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQG 2662
Query: 929 LGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAV 988
++ G+ L + ++LS+Y A++++LL P AL LLEAQAA+G ++DP L+V+EAV
Sbjct: 2663 RSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAV 2722
Query: 989 RRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGG 1048
+ GVVGPEL+ +L AE A+ G++DP++G+Q+S+FQAM+KGLI E RLLEAQ+ATGG
Sbjct: 2723 KEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGG 2782
Query: 1049 IIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRD 1105
+IDP H +P+ VA +RGY D+EM L+ S+ F P+ +Y QLLE C D
Sbjct: 2783 VIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVED 2842
Query: 1106 ETSGLHLLPLPESAPA--------LPTEEQVQRSLQAVPGAK---DGTSLWDLLSSCHFT 1154
+GL LLPL + A + +++ + P K ++W++++S +FT
Sbjct: 2843 PETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFT 2902
Query: 1155 EEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDAGII 1214
EQRR LL + GR TV +++ + V+E + + R+ G R VPA LL++ +I
Sbjct: 2903 AEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE--QKGRLCFEGLRSLVPAAELLESRVI 2960
Query: 1215 TQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTG 1274
+E + L +G +S VAE V+ L G +AGV L+ +G K SI A++ LLP+
Sbjct: 2961 DRELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSD 3020
Query: 1275 LGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRA 1334
+ LLEAQ +G ++DP + RL+V++AV+ GLVG E E+L AE+A GY DPY+
Sbjct: 3021 MAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQ 3080
Query: 1335 SLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLT 1394
S+SL+QA++KGL+P+ +GL LL QL+TGG+VDP +P AC G LD +TS+ L+
Sbjct: 3081 SVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALS 3140
Query: 1395 AVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMK 1454
A D K + DPS + TY +L++RC D TGL LLPL + L+A +
Sbjct: 3141 APRADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARE 3200
Query: 1455 ------VPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVTAL 1508
V V G FKG +V++W+L+ SEY A++R+EL+ R+G+ + + +T +
Sbjct: 3201 TFEKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIV 3260
Query: 1509 VEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
E + + +F GLR V A +L + ++SR ++L G TTVK+++E+ SV+ L+
Sbjct: 3261 EEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQ 3320
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G +AG+ ++ T+E++SI EA+RR +LR TA +LLEAQAATGF++DP N++L V EA
Sbjct: 3321 GSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEA 3380
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 1688
KAG+ G E + +LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATG
Sbjct: 3381 VKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATG 3440
Query: 1689 GIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVE 1748
GIIDPVHSHRVPVDVAY+ GYF EEMNR+LADPSDDTKGFFDPNTHENLTY QLLERCVE
Sbjct: 3441 GIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVE 3500
Query: 1749 DPETGLYLLQI--IKKGE----NYVYINEATRHVLQSRTAKM-RVGRFADQVVSFWDLLS 1801
DPETGL LL + +K E VY E TR + + G +S W+++
Sbjct: 3501 DPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQ 3560
Query: 1802 SPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETE-TQNQGI-KVAAIRGEVTAADL 1859
S E+++ +L+ ++ A E+++ II IE+TE + QG+ +R +TA DL
Sbjct: 3561 SDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDL 3620
Query: 1860 FNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRK 1919
F +R+I +T + LR G + E YL G+ +AGV +P +R+ +S+++A +K
Sbjct: 3621 FEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKK 3680
Query: 1920 ELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYR 1979
L+ A A LLEAQAATGFLLDP ++L+VDEAV GLV EL +RLL AERA TGYR
Sbjct: 3681 GLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYR 3740
Query: 1980 DPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKD 2039
DP T TI LFQAM+K+LI EALRLL+ Q+ATGG++DP+ LPLE AY+RG L+KD
Sbjct: 3741 DPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKD 3800
Query: 2040 IYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDET 2099
+ +S+ +R +VDP+T E++SY +L RCR + TG +L P++ A + +
Sbjct: 3801 THDQLSEPSEVRS-YVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT------- 3852
Query: 2100 RRALEAEQVEITVGRFRG--QKPTLWALLNSEYVTEEKKLQL------VRMYRTHTRRAL 2151
FRG ++ T+ L+ S+ + E LQL + + ++ L
Sbjct: 3853 ---------------FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFL 3897
Query: 2152 QTVAQLILELIE--KQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQE 2209
+ + + ++ K+ S +GI R TA ELL + T ++ ++ + T +E
Sbjct: 3898 EGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 3957
Query: 2210 LMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 2269
+ V + A V P + +S++QAM KG++ + LLEAQ AT
Sbjct: 3958 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4017
Query: 2270 GFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDL 2329
G +IDP + RL VE G+ E+ E L G+ DP T + ++ Q M++ +
Sbjct: 4018 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4077
Query: 2330 IVREHGIRLL-------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 2371
+ G+ LL E + ++ ++DP + V AYR+G D +
Sbjct: 4078 TDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4134
Score = 999 bits (2583), Expect = 0.0
Identities = 666/1843 (36%), Positives = 989/1843 (53%), Gaps = 126/1843 (6%)
Query: 234 TFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLL 293
+F + VSA L E GIL + +Q L +G +++ R +VR YL+G S+AG++L
Sbjct: 2613 SFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLK 2672
Query: 294 PEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELH 353
K S + A LL GTAL LLEAQAA+ L+DP+ +RL V+EAV+ G+V PELH
Sbjct: 2673 ATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELH 2732
Query: 354 EQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRL 413
+LL AE+AVTG+ DP++G QI LFQAM+KGL+ R +RLL+AQ+ATGG++ P R+
Sbjct: 2733 HKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRV 2792
Query: 414 PLEAALRCGCLDEDTQRQLSQA-----GSFSDGTHGGLRYEQLLALCVTDPETGLAFLPL 468
P++ A R G DE+ R L+ G F TH L Y QLL CV DPETGL LPL
Sbjct: 2793 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPL 2852
Query: 469 SG-GPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAML 527
+ +GGE + R AT + GKF+G+ V++WE++ SE ++EQR L
Sbjct: 2853 TDKAAKGGELV---YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDL 2909
Query: 528 AQQYQEGTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLE 587
+Q++ G ++VEK+ + +E+ R+ F GLR V ELL++ +ID++LY++L+
Sbjct: 2910 LRQFRTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQ 2969
Query: 588 HGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQ 647
G+ + +DV + + +R L+G IAG+ L + ++LSIY A K LL A+ LLEAQ
Sbjct: 2970 RGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQ 3029
Query: 648 AATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQ 707
A TG IIDP + +V+EA+RA ++GP+ KLLSAE+AVTGY DPYTGQ +SLFQA++
Sbjct: 3030 AGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALK 3089
Query: 708 KGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGF 767
KGLI RE G+RLL+AQ++TGG++DP SHRVP+DVA RG D+ + L P D K +
Sbjct: 3090 KGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAY 3149
Query: 768 FDPNTHENLTYLQLLERCVRDPETGLYLLPLS-----STQSPLV-DSATQQAFQNLLLSV 821
DP+T E TY +L +RC D TGL LLPLS + Q L + ++ F+ + V
Sbjct: 3150 SDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEV 3209
Query: 822 KYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQVAKLL-----EAETQRQA 876
G F+G+ V+ WELI+SEYF+ +R++LLR++R +VT+ +V K+L E ET RQ
Sbjct: 3210 PVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQE 3269
Query: 877 DIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVR 936
+ LR+ V +LL +G++ + +Q+ G + + L + VR L G G + G+
Sbjct: 3270 RLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIY 3329
Query: 937 LLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPE 996
L + +++S+Y+AMR+ LL A LLEAQAATG ++DP + L V EAV+ GVVGPE
Sbjct: 3330 LEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPE 3389
Query: 997 LYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHH 1056
L+ +L AE A+ G+RDP+SG +S+FQAM+KGL+ + RLLEAQ+ATGGIIDP H
Sbjct: 3390 LHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSH 3449
Query: 1057 HLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRDETSGLHLL 1113
+P+ VA QRGY +EM L+ S+ F P+ +Y QLLE C D +GL LL
Sbjct: 3450 RVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLL 3509
Query: 1114 PLPESAPA-------LPTEEQVQRSLQA----VPG----AKDGTSLWDLLSSCHFTEEQR 1158
PL + A + TEE+ +R+ + +PG SLW+++ S EEQR
Sbjct: 3510 PLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQR 3569
Query: 1159 RGLLEDVQEGRTTVPQLLASVQRWVQETKLL-AQARVMVPGPRGEVPAVWLLDAGIITQE 1217
L+ D Q GR T +++ + +++T+++ Q R + A L +A II+ E
Sbjct: 3570 AQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLE 3629
Query: 1218 TLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQ 1277
T L +GT+S + E + L+GTG VAGV L S SI QA++ GLL + +
Sbjct: 3630 TYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVAR 3689
Query: 1278 RLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLS 1337
LLEAQ A+GFL+DP+ +RL+V++AV+ GLVG EL ++L AERA GY DPY+ ++S
Sbjct: 3690 LLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTIS 3749
Query: 1338 LWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVD 1397
L+QAM+K L+P E L LL QLATGG+VDP G HLP A + G L+ T L+
Sbjct: 3750 LFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSE-P 3808
Query: 1398 KDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPV 1457
+ + + DPS ++++Y QL RC D TG LLLPL D + R ++ +
Sbjct: 3809 SEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPL--------SDARKLTFRGLRKQI 3860
Query: 1458 STGRFKGCSVSLWDLLLSEYVGADKRRELVALCR-SGRAAALRQVVSAVTALVEAAERQP 1516
+ V + E R L ++ + + S + + A ++
Sbjct: 3861 TMEELVRSQV------MDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKER 3914
Query: 1517 L---QATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSV-----KRSLE 1568
L QA +G+ + +A +L AQ + +D + TV+E M V + L
Sbjct: 3915 LSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLS 3974
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
+ G + + +S+ +A+++ ++ + LLEAQ ATG IIDP E+ +L VE A
Sbjct: 3975 AERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVA 4034
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL------- 1681
+K G+F +E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4035 YKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKR 4094
Query: 1682 EAQIATGG--------IIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNT 1733
E + ++ I+DP + V AYR G D +
Sbjct: 4095 ERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ-------------------- 4134
Query: 1734 HENLTYLQLLERCVEDPE------TGLYLLQIIKKGENYVY-INEATRHVLQSRTAKMRV 1786
TYL+L E+ E E G+ II + Y I++A L R+A +
Sbjct: 4135 ----TYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRSALDQY 4190
Query: 1787 GRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIK 1846
+ F D+LS R G+ S T ++ +
Sbjct: 4191 RAGTLSITEFADMLSG---NAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGP 4247
Query: 1847 VAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPS 1906
VA I T +V + +H V GQ L LE C G+ PS
Sbjct: 4248 VAGILDTETL-----EKVSITEAMHRNLVDNITGQRL---------LEAQACTGGIIDPS 4293
Query: 1907 TREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRE 1966
T E + +A K L+ + AQ A DP T+ K+S +A+ G + E +
Sbjct: 4294 TGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQ 4353
Query: 1967 RLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEV 2009
R L+ + G +P T +PL +A+Q+ ++ A +L +V
Sbjct: 4354 RFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV 4396
Score = 970 bits (2508), Expect = 0.0
Identities = 547/1287 (42%), Positives = 810/1287 (62%), Gaps = 33/1287 (2%)
Query: 1155 EEQRRGLL---EDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDA 1211
EEQ R L E+V + + L + + + A+ G R +V A L +A
Sbjct: 2570 EEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEA 2629
Query: 1212 GIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLL 1271
GI++ E L+ LAQG + ++A + V+ L G +AG+LL+ + K S+ A++ LL
Sbjct: 2630 GILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLL 2689
Query: 1272 PTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPY 1331
G LLEAQ ASGFL+DP+ N+RL+V +AVK G+VG EL +L AERA GY DPY
Sbjct: 2690 SPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPY 2749
Query: 1332 SRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQ 1391
+ +SL+QAM+KGL+ + G+ LL+ Q+ATGGV+DPVH +P A R G D + ++
Sbjct: 2750 TGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNR 2809
Query: 1392 VLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDT-----VLEVDDHT 1446
VL D K FFDP+ + +TY QL ERCV D ETGL LLPL ++ D
Sbjct: 2810 VLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEA 2869
Query: 1447 AVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVT 1506
V G+F+G +V++W+++ SEY A++RR+L+ R+GR + +++ +
Sbjct: 2870 RDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRIT-VEKIIKIII 2928
Query: 1507 ALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRS 1566
+VE E++ + F GLR V A +L +++I R+ +L +G +V++VAE+D+V+R+
Sbjct: 2929 TVVEEQEQKG-RLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 2987
Query: 1567 LEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVE 1626
L G N IAGV ++ +++SI AL++ +L A+ LLEAQA TG IIDPA + +LTV+
Sbjct: 2988 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVD 3047
Query: 1627 EAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIA 1686
EA +AG+ G E + KLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++
Sbjct: 3048 EAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLS 3107
Query: 1687 TGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERC 1746
TGGI+DP SHRVP+DVA G DEE +R L+ P D K + DP+T E TY +L +RC
Sbjct: 3108 TGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRC 3167
Query: 1747 VEDPETGLYLLQIIKKG----ENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSS 1802
D TGL LL + +K + +Y R + ++ VG F + V+ W+L+SS
Sbjct: 3168 RPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3227
Query: 1803 PYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQG-IKVAAIRGEVTAADLFN 1861
YFT ++++EL++++ +EK+++I+ T +EE ET Q + + +R V A++L
Sbjct: 3228 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3287
Query: 1862 SRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKEL 1921
S V+ + L+ G+T + LS L V+ L+GS C+AG+ + T+E +S++EA R+ L
Sbjct: 3288 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3347
Query: 1922 IPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDP 1981
+ A A LLEAQAATGFL+DP Q+L V EAV G+V EL E+LL AE+A TGYRDP
Sbjct: 3348 LRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDP 3407
Query: 1982 ATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIY 2041
+G TI LFQAMQK L+ + +RLLE Q+ATGG+IDP H HR+P++ AY+RG +++
Sbjct: 3408 YSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMN 3467
Query: 2042 ALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSE-------H 2094
+++D K F DPNT E ++YR+L ERC +TG L P+ K A +E +
Sbjct: 3468 RVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL-KGAEKAEVVETTQVY 3526
Query: 2095 IDDETRRALEAEQVEITVGRFRGQKP-TLWALLNSEYVTEEKKLQLVRMYRTHTRRALQT 2153
++ETRRA E Q++I G G +LW ++ S+ + EE++ QL+ ++ R +
Sbjct: 3527 TEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAG-RVTKER 3585
Query: 2154 VAQLILELIEKQETSNKH--LWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELM 2211
+ +I+E+IEK E + + +RR++TA +L + II+ E L G + +E +
Sbjct: 3586 MIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREAL 3645
Query: 2212 EDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGF 2271
E + YL GT +AGV +P G ++ +SIYQA+ KG+L A +LLEAQAATGF
Sbjct: 3646 EAESAWCYLYGTGSVAGVYLP-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGF 3700
Query: 2272 VIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIV 2331
++DPV+ RL+V+E V G+VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3701 LLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIP 3760
Query: 2332 REHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNT 2391
E +RLL+AQ+ATGG++DP +P++VAY+RGY +++ + L++PS + + + DP+T
Sbjct: 3761 TEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPST 3819
Query: 2392 HENLTYVQLLRRCVPDPDTGLYMLQLA 2418
E L+Y QLLRRC D TG +L L+
Sbjct: 3820 DERLSYTQLLRRCRRDDGTGQLLLPLS 3846
Score = 881 bits (2277), Expect = 0.0
Identities = 629/1746 (36%), Positives = 913/1746 (52%), Gaps = 133/1746 (7%)
Query: 41 RSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQ 100
R++ G +GQ S++ AM++GL+ G LLEAQ ATGG++D +PV A +
Sbjct: 2740 RAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR 2799
Query: 101 QGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEV--QLATG 158
+G E+ L T G+ DP E L Q + + V D G L + + A G
Sbjct: 2800 RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKG 2859
Query: 159 GLV----DPAQGVLVAPEPACHQGLLDRET---WHKLSELEPGTGDLR--FLNPNTLERL 209
G + A+ V + G +T W ++ E T + R L R+
Sbjct: 2860 GELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINS-EYFTAEQRRDLLRQFRTGRI 2918
Query: 210 TYHQLLERCVRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAV 269
T ++++ + ++ F + V AAELLE ++D + Q L+ G +
Sbjct: 2919 TVEKIIKIIITVVEEQEQ--KGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVR 2976
Query: 270 DVSARAEVRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLV 329
DV+ VRR L G +AGV L G K S + A + LLP A+ LLEAQA T ++
Sbjct: 2977 DVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHII 3036
Query: 330 DPITGQRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRP 389
DP T RL VDEAVRAGLV PE HE+LL AE+AVTG+ DP++G + LFQA+KKGL+ R
Sbjct: 3037 DPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPRE 3096
Query: 390 LALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLS----QAGSFSDGTHGG 445
LRLLDAQL+TGG+V P++ R+PL+ A GCLDE+T R LS A ++SD + G
Sbjct: 3097 QGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGE 3156
Query: 446 -LRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFR 504
Y +L C D TGL+ LPLS Q + + R+ V VG F+
Sbjct: 3157 PATYGELQQRCRPDQLTGLSLLPLSEKAARAR-QEELYSELQARETFEKTPVEVPVGGFK 3215
Query: 505 GRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAELSATLEQAAATA--RVTFSG 562
GR V++WEL+ SE ++EQR L +Q++ G ++VEK+ L +E+ R++FSG
Sbjct: 3216 GRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSG 3275
Query: 563 LRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQE 622
LR V ELL + ++ + +E+L+ G+ T KD+ L S + LQG+GC+AG+ L ++E
Sbjct: 3276 LRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKE 3335
Query: 623 RLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLL 682
++SIYEA +GLLR TA +LLEAQAATGF++DP N+ V EA++A V+GP++ +LL
Sbjct: 3336 KVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLL 3395
Query: 683 SAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDV 742
SAE+AVTGY DPY+G ISLFQAMQKGL++R+HGIRLLEAQIATGG+IDPVHSHRVPVDV
Sbjct: 3396 SAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3455
Query: 743 AYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQ 802
AY+RGYF + +N +L DPSDDTKGFFDPNTHENLTY QLLERCV DPETGL LLPL +
Sbjct: 3456 AYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAE 3515
Query: 803 SPLV--------DSATQQAFQNLLLSVK-YGRFQGQRVSAWELINSEYFSEGRRRQLLRR 853
V + T++AF+ + + G G +S WE++ S+ E +R QL+
Sbjct: 3516 KAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMAD 3575
Query: 854 YRQREVTLGQVAKLL-----EAETQRQADI-MLPALRSRVTVHQLLEAGIIDQQLLDQVL 907
++ VT ++ ++ + E RQ + +R R+T L EA II + + +
Sbjct: 3576 FQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLR 3635
Query: 908 AGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQ 967
GT S L + YL G G+V GV L S Q LS+YQA+++ LL VA LLEAQ
Sbjct: 3636 EGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQ 3695
Query: 968 AATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMK 1027
AATG ++DP E L+VDEAVR+G+VGPEL+ RL AE A+ G+RDP++ + +S+FQAMK
Sbjct: 3696 AATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMK 3755
Query: 1028 KGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSE--TFP 1085
K LIP E+A RLL+AQ+ATGGI+DP HLP+ VA QRGY++++ LS SE ++
Sbjct: 3756 KELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYV 3815
Query: 1086 TPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGTSLW 1145
P R SY QLL C RD+ +G LLPL ++ R L G + ++
Sbjct: 3816 DPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDA-----------RKL-TFRGLRKQITME 3863
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+ S E L +EG T++ ++ ++Q++++ T + A V V + +
Sbjct: 3864 ELVRSQVMDEATALQL----REGLTSIEEVTKNLQKFLEGTSCI--AGVFVDATKERLSV 3917
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAE---------QPAVKACLWG----------TG 1246
+ GII T L + + V + + AV+ + G
Sbjct: 3918 YQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAER 3977
Query: 1247 CVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKV 1306
V G SG S+ QA++ GL+ G RLLEAQ+A+G ++DP + RL VE A K
Sbjct: 3978 AVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKR 4037
Query: 1307 GLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLL---------- 1356
GL E++E L G+ DP + +L+ Q ME+ + GL LL
Sbjct: 4038 GLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERK 4097
Query: 1357 -----QVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQ 1411
V+ +VDP G + A R GL+D QT L+ + + ++
Sbjct: 4098 TSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECE---------WEE 4148
Query: 1412 VTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLW- 1470
+T D +++ S ++DD A L + +++ ++S+
Sbjct: 4149 ITISS------SDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRS---ALDQYRAGTLSITE 4199
Query: 1471 --DLLLSEYVGADKRRELVALCRS---GRAAALRQVVS---------AVTALVEAAERQP 1516
D+L G R V S A + Q+ S V +++ +
Sbjct: 4200 FADMLSGNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEK 4259
Query: 1517 L---QATFRGLRKQVSARDLFRAQ-----LISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
+ +A R L ++ + L AQ +I T + K + + V R
Sbjct: 4260 VSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINL 4319
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G T+ +MS +AL++ L LE Q TG +I+P ++ ++EA
Sbjct: 4320 AQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEA 4379
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-AT 1687
+ G T KL T P T +IS A+ + ++ G+RLLEA +T
Sbjct: 4380 LQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4439
Query: 1688 GGIIDP 1693
G P
Sbjct: 4440 KGYYSP 4445
Score = 869 bits (2246), Expect = 0.0
Identities = 711/2089 (34%), Positives = 1014/2089 (48%), Gaps = 390/2089 (18%)
Query: 2610 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 2665
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2502 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2561
Query: 2666 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 2712
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2562 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2618
Query: 2713 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 2772
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2619 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2675
Query: 2773 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 2832
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2676 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2733
Query: 2833 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2892
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2734 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2793
Query: 2893 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL- 2951
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L
Sbjct: 2794 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2853
Query: 2952 --AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRY 3009
A +G + E R A V+ G QG++V++WE++ + ++R+DLL ++
Sbjct: 2854 DKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQF 2913
Query: 3010 RAGTLTVEELGATLTSLLAQAQAQAR----------AEAEAGSPRPDPREALR------- 3052
R G +TVE++ + +++ + + + R AE R RE +
Sbjct: 2914 RTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGER 2973
Query: 3053 ----AATMEVKVGRLRGRAV--PVWDVLASGYVS--GAAREELL----------AEFGSG 3094
A ++ LRG V VW A +S A +++LL A+ G+G
Sbjct: 2974 SVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTG 3033
Query: 3095 TLDLPALTRRLTAIIEEAEEAPGARPQL--------------QDAWRG------------ 3128
+ PA + RLT ++EA A P+ +D + G
Sbjct: 3034 HIIDPATSARLT--VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKG 3091
Query: 3129 --PREPG-------PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQ 3168
PRE G + G D +S R G + ET A +A A A
Sbjct: 3092 LIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSD 3151
Query: 3169 EQTLRDATM-EVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLT 3227
T AT E+Q+ + + + S + AR++EL ++ A
Sbjct: 3152 PSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------R 3199
Query: 3228 RVIEETEERLSKVSFRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV----- 3278
E+T + F+G R V+ EL +S E LR G T+++V
Sbjct: 3200 ETFEKTPVEVPVGGFKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILI 3257
Query: 3279 TEMDSVKRYLEGTSCIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALV 3329
T ++ V+ + +G+ VPA + + E++ + K + G+
Sbjct: 3258 TIVEEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRT 3317
Query: 3330 LLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP-------- 3381
LL+ + ++S+ EA+ G++ LL A+ A DP
Sbjct: 3318 LLQGSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYV 3377
Query: 3382 ------------------------------YTGQQISLFQAMQKDLIVREHGIRLLEAQI 3411
Y+G ISLFQAMQK L++R+HGIRLLEAQI
Sbjct: 3378 HEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQI 3437
Query: 3412 ATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRR 3471
ATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL R
Sbjct: 3438 ATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLER 3497
Query: 3472 CVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWE 3524
CV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+WE
Sbjct: 3498 CVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWE 3557
Query: 3525 LLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA 3572
++ + E++R L++ ++AG +T E + + ++ + + + R A
Sbjct: 3558 VMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTA 3617
Query: 3573 ----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDV 3607
EA + LR T ++ G + G +P ++
Sbjct: 3618 EDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQA 3677
Query: 3608 LASGYVSG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREP 3666
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3678 LKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER- 3734
Query: 3667 GPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVW 3726
A G D Q + +E A R + L + R F P+ V
Sbjct: 3735 --AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV- 3790
Query: 3727 DVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------- 3772
YL++ D+ L + V + V T+ERLS
Sbjct: 3791 -AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGT 3838
Query: 3773 -----------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 3821
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++
Sbjct: 3839 GQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKF 3896
Query: 3822 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 3881
LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L
Sbjct: 3897 LEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGL 3951
Query: 3882 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 3941
+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLL
Sbjct: 3952 KLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLL 4011
Query: 3942 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQ 4001
EAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+Q
Sbjct: 4012 EAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQ 4071
Query: 4002 LLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLF 4061
L+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4072 LMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYEA-- 4125
Query: 4062 YREVSEDRRQDL-LSRYRA--STLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREA 4118
YR+ D + L LS +T+ + S++
Sbjct: 4126 YRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMI----------------------- 4162
Query: 4119 LRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIE 4178
+ R GR + D +A + R+A L ++ +GTL + L+
Sbjct: 4163 ---------IDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS---- 4205
Query: 4179 EAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ 4238
G++G + G + + A +R Q
Sbjct: 4206 -----------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLA 4236
Query: 4239 TLRDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDL 4290
+ D T E G G VS+ + + + + LL AQ G +
Sbjct: 4237 SWSDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI----- 4289
Query: 4291 VAVLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTL 4343
+ T ER ++ +GL ++ ++ + G P T ++
Sbjct: 4290 ------IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4343
Query: 4344 QEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQA 4403
+ ++ +R+LE G++ P D PGR + + +A+ +G + TA L + A
Sbjct: 4344 KGWLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGA 4398
Query: 4404 ATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 4451
+ ++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4399 YSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4447
Score = 852 bits (2202), Expect = 0.0
Identities = 715/2192 (32%), Positives = 1042/2192 (47%), Gaps = 408/2192 (18%)
Query: 1960 VNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEAL----RLLEVQVATGG 2015
+ +E + LK+E T ++ +T QA+Q+ + + ++L R +E + A
Sbjct: 2430 LQQEAKLLQLKSEEMQTVQQEQLLQET----QALQQSFLSEKDSLLQRERFIEQEKAKLE 2485
Query: 2016 VI---DPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERC 2072
+ + +L E ++ + ++ L++ + R+R + + ELQ+
Sbjct: 2486 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2545
Query: 2073 RPQEDTGWVLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVT 2132
+ + +L N+ R+ + +E RA A E+T + K
Sbjct: 2546 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL----------- 2594
Query: 2133 EEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSAII 2192
+ R AL A E +H F G+RR+++A L + I+
Sbjct: 2595 ------------PNGRDALDGPA---------AEAEPEHS-FDGLRRKVSAQRLQEAGIL 2632
Query: 2193 TEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKG 2252
+ E LQ L G +T EL + V+ YL+G S IAG+L+ A + EK+S+Y A+ +
Sbjct: 2633 SAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN-----EKLSVYAALQRQ 2687
Query: 2253 VLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTD 2312
+L PGTAL+LLEAQAA+GF++DPVRN RL+V E V GVVG E+ KLLSAERAVTGY D
Sbjct: 2688 LLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKD 2747
Query: 2313 PYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2372
PYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM
Sbjct: 2748 PYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2807
Query: 2373 NRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL---AGRGSAVHQLSE 2429
NRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L A +G +
Sbjct: 2808 NRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDS 2867
Query: 2430 ELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATL 2489
E R A V+ G QG++V++WE++ + ++R+DLL ++R G +TVE++ +
Sbjct: 2868 EARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKII 2927
Query: 2490 TSLLAQAQAQAR----------AEAEAGSPRPDPREALR-----------AATMEVKVGR 2528
+++ + + + R AE R RE + A ++
Sbjct: 2928 ITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 2987
Query: 2529 LRGRAV--PVWDVLASGYVS--RAAREELL----------AEFGSGTLDLPALTRRLTAI 2574
LRG V VW A +S A +++LL A+ G+G + PA + RLT
Sbjct: 2988 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLT-- 3045
Query: 2575 IEEAEEAPGARPQ--------------------------LQDARRG--PREPG------- 2599
++EA A P+ Q ++G PRE G
Sbjct: 3046 VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQ 3105
Query: 2600 PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQEQTLRDATM-EVQR 2647
+ G D +S R G + ET A +A A A T AT E+Q+
Sbjct: 3106 LSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQ 3165
Query: 2648 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVS 2707
+ + + S + AR++EL ++ A E+T +
Sbjct: 3166 RCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------RETFEKTPVEVPVGG 3213
Query: 2708 FRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV-----TEMDSVKRYLEGTS 2758
F+G R V+ EL +S E LR G T+++V T ++ V+ +
Sbjct: 3214 FKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERL 3271
Query: 2759 CIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDP 2809
+G+ VPA + + E++ + K + G+ LL+ +
Sbjct: 3272 SFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLE 3331
Query: 2810 VRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP---------------------- 2847
++S+ EA+ G++ LL A+ A DP
Sbjct: 3332 DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELH 3391
Query: 2848 ----------------YTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRV 2891
Y+G ISLFQAMQK L++R+HGIRLLEAQIATGG+IDPVHSHRV
Sbjct: 3392 EQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRV 3451
Query: 2892 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL 2951
PVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+TGL +L L
Sbjct: 3452 PVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL 3511
Query: 2952 AGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYREVSEDRRQD 3004
G A EE R A + ++ PG G+ G ++S+WE++ + E++R
Sbjct: 3512 KGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQ 3571
Query: 3005 LLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EAGSPRPDPR 3048
L++ ++AG +T E + + ++ + + + R A EA +
Sbjct: 3572 LMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETY 3631
Query: 3049 EALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYVSG-AAREE 3086
LR T ++ G + G +P ++ L G +S AR
Sbjct: 3632 NLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLL 3691
Query: 3087 LLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQ 3146
L A+ +G L P RLT ++EA P+L D A G D Q
Sbjct: 3692 LEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTGYRDPYTEQ 3746
Query: 3147 REGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRD 3206
+ +E A R + L + R F P+ V YL++ D
Sbjct: 3747 TISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRGYLNKDTHD 3803
Query: 3207 ELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------------KVS 3241
+ L + V + V T+ERLS K++
Sbjct: 3804 Q-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT 3852
Query: 3242 FRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPA 3301
FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSCIAGV V A
Sbjct: 3853 FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSCIAGVFVDA 3910
Query: 3302 KDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVG 3361
+E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEEAV G+VG
Sbjct: 3911 -----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVG 3965
Query: 3362 GEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVH 3421
E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIATGG+IDP
Sbjct: 3966 PEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEE 4025
Query: 3422 SHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLY 3481
SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+QL+ RC+ DP TGL
Sbjct: 4026 SHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLC 4085
Query: 3482 MLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLS 3541
+L L + S+ R V P + G+ +SV+E
Sbjct: 4086 LLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE----------------- 4124
Query: 3542 RYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRA 3601
YR G + + T L Q E S + + R GR
Sbjct: 4125 AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------DGVVKSMIIDRRSGRQ 4170
Query: 3602 VPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWR 3661
+ D +A + +A L ++ +GTL + L+
Sbjct: 4171 YDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS--------------------- 4205
Query: 3662 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG- 3720
G++G + G + + A +R Q + D T E G G
Sbjct: 4206 ------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEET--GPVAGI 4251
Query: 3721 ------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVAVLTRVIEETEER--L 3771
VS+ + + + + LL AQ G + + T ER +
Sbjct: 4252 LDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI-----------IDPSTGERFPV 4300
Query: 3772 SKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTS 3826
+ +GL ++ ++ + G P T ++ + ++ +R+LE
Sbjct: 4301 TDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQY 4360
Query: 3827 CIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVE 3886
G++ P D PGR + + +A+ +G + TA L + A + ++ P L++S +
Sbjct: 4361 LTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYK 4415
Query: 3887 EAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3917
+A+ +V +LL +A ++ GY PY+
Sbjct: 4416 DALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4447
Score = 727 bits (1876), Expect = 0.0
Identities = 710/2292 (30%), Positives = 1038/2292 (45%), Gaps = 316/2292 (13%)
Query: 3017 EELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLAS 3076
EE+ A S A +A E E G R + + LR+ + ++ R R + +
Sbjct: 1893 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE-QAELEAARQRQLAAEEERRR 1951
Query: 3077 GYVSGAAREELLAEFGSGTLDLPAL--TRRLTAIIEEAE------EAPGARPQLQDAWRG 3128
++ L AE + AL RL A +EEA E AR QLQ A
Sbjct: 1952 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEA 2010
Query: 3129 PREPGPAGRGDGDSGRSQREGQGEGETQEAAAA-------AAAARRQEQTLRDATMEVQR 3181
++ A Q+E + + Q+ + A AARR + +A ++ +R
Sbjct: 2011 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2070
Query: 3182 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAV-LTRVIEETEERLSKV 3240
Q R + EA R + A+ A A A L + E+ R ++
Sbjct: 2071 EAAQSR----------RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2120
Query: 3241 SFRGLR-RQVSASELHTSGILGPETLRDLAQGTKTLQ----EVTEMDSVKRYL-EGTSCI 3294
LR +Q + +E+ +TLR AQ + L ++ E D K L E +
Sbjct: 2121 EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRL 2180
Query: 3295 AGVLVPAKDQPGRQEK--------MSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 3346
A Q + E+ M + + AL+L + F+ +
Sbjct: 2181 KAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEK 2240
Query: 3347 LRLSVEEAVAAGVVGGE----------------------IQEKLLSAERAVTGYTDPYTG 3384
++ EEA V E ++EK+ + + A +
Sbjct: 2241 MKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2300
Query: 3385 QQ---ISLFQA---------MQKDLIVREHGI-RLLEA----QIATGGVIDPVHSHRVPV 3427
QQ ++ QA M + L G R LEA Q+ + + +
Sbjct: 2301 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2360
Query: 3428 DVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLL--RRCVPDPDTGLYMLQL 3485
A R D + R A+ + + T E +T VQ L +R D D +
Sbjct: 2361 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI 2420
Query: 3486 AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRA 3545
A +L +E + L + Q Q + + L +SE + LL R R
Sbjct: 2421 AELEREKEKLQQEAK--LLQLKSEEMQTVQQEQLLQETQALQQSFLSE--KDSLLQRERF 2476
Query: 3546 GTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPV- 3604
+L +A+AQ Q R E + + + A+ME R V
Sbjct: 2477 IEQEKAKLEQLFQDEVAKAQ-QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2535
Query: 3605 --WDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRG 3662
+ L +EELLAE + L +L + E+ A ++ +
Sbjct: 2536 RKQEELQQLEQQRRQQEELLAE------ENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2589
Query: 3663 PREPGPAGRG--DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG 3720
+ P GR DG + ++ E +G ++ +A R QE + A E+QR QG
Sbjct: 2590 ATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ----RLQEAGILSAE-ELQR-LAQG 2643
Query: 3721 RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 3780
+ E R E + + G + L+ ++ T E+LS + L+
Sbjct: 2644 HTT----------VDELARREDVRHYLQGRSSIAGLL------LKATNEKLSV--YAALQ 2685
Query: 3781 RQVSA---------SELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 3831
RQ+ + ++ + +L P R L + V + + L + G
Sbjct: 2686 RQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGY 2745
Query: 3832 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 3891
P Q ++S++QAM KG++ + LLEAQ ATG VIDPV + R+ V+ A
Sbjct: 2746 KDPYTGQ-----QISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRR 2800
Query: 3892 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEA--QIATGG 3949
G E+ L G+ DP T + ++ Q +++ + E G+ LL + A GG
Sbjct: 2801 GYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGG 2860
Query: 3950 VI--------DPVHSHRVPVDVAYRRG------------YFDEEMNRVLADPSDDTKGFF 3989
+ D V +G YF E R L +
Sbjct: 2861 ELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITV 2920
Query: 3990 DPNTHENLTYVQL-----------LRRCVPDP--------DTGLYMLQLAGRGSAVHQLS 4030
+ +T V+ LR VP D LY QL +V ++
Sbjct: 2921 EKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQ-QLQRGERSVRDVA 2979
Query: 4031 E--ELRCALRDARVTPGSGALQ-GQSVSVWELLFYREVSEDRRQDLLSRYRASTLTVEEL 4087
E +R ALR A V G + GQ +S++ L ++DLL A L +
Sbjct: 2980 EVDTVRRALRGANVIAGVWLEEAGQKLSIYNAL---------KKDLLPSDMAVALLEAQA 3030
Query: 4088 GAT-LTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGR--LRGRAVPVWDVLAS 4144
G + A+ AG P+ E L +A V R G++V ++ L
Sbjct: 3031 GTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKK 3090
Query: 4145 GYVSRAAREELL-AEFGSGTLDLPALTRRLTAII--------EEAEEAPGARPQLQDAWR 4195
G + R LL A+ +G + P+ + R+ + EE A A A+
Sbjct: 3091 GLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYS 3150
Query: 4196 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ---------TLRDATME 4246
P PA G+ + R Q G + + AA RQE+ T +E
Sbjct: 3151 DPSTGEPATYGELQ--QRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVE 3208
Query: 4247 VQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEE-RL 4305
V G F+GR V+VW+++ S Y + +R ELL Q G + + ++ +L ++EE E R
Sbjct: 3209 VPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQ 3268
Query: 4306 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 4365
++SF GLR V ASEL SG+L L G T+++++E+ SV+ L+G+ C+AG+
Sbjct: 3269 ERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGI 3328
Query: 4366 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 4425
+ +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL V EAV A
Sbjct: 3329 YLE-----DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKA 3383
Query: 4426 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 4485
GVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATGG+I
Sbjct: 3384 GVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGII 3443
Query: 4486 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 4545
DPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+
Sbjct: 3444 DPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPE 3503
Query: 4546 TGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYRE 4598
TGL +L L G A EE R A + ++ PG G+ G ++S+WE++
Sbjct: 3504 TGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDL 3563
Query: 4599 VSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EA 4642
+ E++R L++ ++AG +T E + + ++ + + + R A EA
Sbjct: 3564 IPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEA 3623
Query: 4643 GSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYV 4681
+ LR T ++ G + G +P ++ L G +
Sbjct: 3624 RIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLL 3683
Query: 4682 SG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRG 4740
S AR L A+ +G L P RLT ++EA P+L D A G
Sbjct: 3684 SAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTG 3738
Query: 4741 DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSS 4800
D Q + +E A R + L + R F P+ V
Sbjct: 3739 YRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRG 3795
Query: 4801 YLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------- 4840
YL++ D+ L + V + V T+ERLS
Sbjct: 3796 YLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLP 3844
Query: 4841 -----KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSC 4895
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSC
Sbjct: 3845 LSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSC 3902
Query: 4896 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 4955
IAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEE
Sbjct: 3903 IAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 3957
Query: 4956 AVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 5015
AV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIAT
Sbjct: 3958 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4017
Query: 5016 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRAT 5075
GG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTYLQL++R
Sbjct: 4018 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4077
Query: 5076 LDPETGLLFLSL 5087
DP+TGL L L
Sbjct: 4078 TDPQTGLCLLPL 4089
Score = 619 bits (1597), Expect = e-176
Identities = 476/1531 (31%), Positives = 736/1531 (48%), Gaps = 227/1531 (14%)
Query: 40 ARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKAL 99
A IAGV++E +GQ S+Y A+++ LLP+ + ALLEAQA TG ++D A L V +A+
Sbjct: 2991 ANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEAV 3050
Query: 100 QQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGG 159
+ GLVG E EKLL+AE+A TGY DPY G+ ++LFQA+ K ++ R G L+ QL+TGG
Sbjct: 3051 RAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTGG 3110
Query: 160 LVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCV 219
+VDP++ V + AC +G LD ET LS P + +P+T E TY +L +RC
Sbjct: 3111 IVDPSKSHRVPLDVACARGCLDEETSRALS--APRADAKAYSDPSTGEPATYGELQQRCR 3168
Query: 220 RAPGSGLALLPL------------------KITFRS----------MGGAVSAAELLEVG 251
+GL+LLPL + TF G V+ EL+
Sbjct: 3169 PDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISSE 3228
Query: 252 ILD-EQAVQGLREGRLAAV--------------DVSARAEVRRYLEGTGS--------VA 288
EQ + LR+ R V +V + R G + +
Sbjct: 3229 YFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLAS 3288
Query: 289 GVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAG-- 346
GV+ + + + + L +G+ LL+ + T +++ + EA+R G
Sbjct: 3289 GVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGLL 3348
Query: 347 -----------------LVSPELHEQLLVAE-------------------QAVTGHHDPF 370
LV P +++L V E +AVTG+ DP+
Sbjct: 3349 RATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDPY 3408
Query: 371 SGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQR 430
SGS I LFQAM+KGLV R +RLL+AQ+ATGG++ P R+P++ A + G E+ R
Sbjct: 3409 SGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMNR 3468
Query: 431 QLSQ-----AGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPP-FIK 484
L+ G F TH L Y QLL CV DPETGL LPL G + + + +
Sbjct: 3469 VLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVETTQVYTE 3528
Query: 485 YSTRQALSTATATV-SVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAA 543
TR+A + G G +SLWE++ S+ I EQRA L +Q G ++ E++
Sbjct: 3529 EETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMII 3588
Query: 544 ELSATLEQAAATAR---VTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLA 600
+ +E+ + ++ +R +T +L +A II + Y L G + ++
Sbjct: 3589 IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAE 3648
Query: 601 SAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANK 660
SA YL GTG +AG+ LPGS++ LSIY+A KGLL A +LLEAQAATGF++DP +
Sbjct: 3649 SAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGE 3708
Query: 661 GHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLL 720
+V+EA+R ++GP++ +LLSAERAVTGY DPYT Q ISLFQAM+K LI E +RLL
Sbjct: 3709 RLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLL 3768
Query: 721 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQ 780
+AQ+ATGG++DP +P++VAY+RGY ++ + L +PS + + + DP+T E L+Y Q
Sbjct: 3769 DAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQ 3827
Query: 781 LLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSE 840
LL RC RD TG LLPLS A + F+ L ++++ EL+ S+
Sbjct: 3828 LLRRCRRDDGTGQLLLPLS--------DARKLTFRGL----------RKQITMEELVRSQ 3869
Query: 841 YFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQ 900
E QL E + K LE T A + + A + R++V+Q ++ GII
Sbjct: 3870 VMDEATALQLREGLTSIEEVTKNLQKFLEG-TSCIAGVFVDATKERLSVYQAMKKGIIRP 3928
Query: 901 QLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVA 960
++L A G V G +L++ +A+R ++GP
Sbjct: 3929 GTAFELLEAQ-------------------AATGYVIDPIKGLKLTVEEAVRMGIVGPEFK 3969
Query: 961 LALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQV 1020
LL A+ A DP+S + +S+ +A+++G++ + RL A+ A G DP ++
Sbjct: 3970 DKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRL 4029
Query: 1021 SVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSS 1080
V A K+GL E L + T G DP + +L
Sbjct: 4030 PVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENL---------------------- 4067
Query: 1081 SETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPT--EEQVQRSLQAVPGA 1138
+Y QL+E C D +GL LLPL E T + V++ +
Sbjct: 4068 -------------TYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDP 4114
Query: 1139 KDGTSLWDLLSSCHFTEEQRRGLLE-----DVQEGRTTVPQLLASVQRWVQETKLLAQAR 1193
+ G + E R+GL++ ++ E ++ S V ++ ++ +
Sbjct: 4115 ETGKEM-------SVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRR- 4166
Query: 1194 VMVPGPRGEVPAVWLLDAGIITQETLEALAQGTQSPAQVAE------------------- 1234
G + ++ + +I + L+ GT S + A+
Sbjct: 4167 ---SGRQYDIDDA--IAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSS 4221
Query: 1235 -----QPAV---KACLWG-----TGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLE 1281
PAV + W TG VAG+L + K SI +A+ L+ GQRLLE
Sbjct: 4222 SSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLE 4281
Query: 1282 AQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQA 1341
AQ +G ++DP +R V DAV GLV + + +++ A++A G+ DP ++ +S QA
Sbjct: 4282 AQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQA 4341
Query: 1342 MEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNK 1401
++KG + G L+VQ TGG+++P +P A + G +D +T+Q L V +K
Sbjct: 4342 LKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSK 4401
Query: 1402 FFFDPSARDQVTYQQLRERCVCDSETGLLLL 1432
+ P + +++Y+ +R + + TGL LL
Sbjct: 4402 YLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4432
Score = 350 bits (897), Expect = 3e-95
Identities = 288/927 (31%), Positives = 451/927 (48%), Gaps = 110/927 (11%)
Query: 4243 ATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE 4302
AT+ G+FQG+ V++W+++ S Y + +R +LL Q G + + ++ ++ V+EE E
Sbjct: 2876 ATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE 2935
Query: 4303 ERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCI 4362
++ ++ F GLR V A+EL S ++ E + L +G +++++V E+D+V+R L G + I
Sbjct: 2936 QK-GRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRALRGANVI 2994
Query: 4363 AGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEA 4422
AGV + Q K+SIY A+ K +L A+ LLEAQA TG +IDP + RL+V+EA
Sbjct: 2995 AGVWLEEAGQ-----KLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEA 3049
Query: 4423 VAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 4482
V AG+VG E EKLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++TG
Sbjct: 3050 VRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTG 3109
Query: 4483 GVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVP 4542
G++DP SHRVP+DVA RG DEE +R L+ P D K + DP+T E TY +L +RC P
Sbjct: 3110 GIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRCRP 3169
Query: 4543 DPDTGLYMLQLAGRGSAVHQLSEELRCALRDARV---TPGS---GALQGQSVSVWELLFY 4596
D TGL +L L+ + + Q EEL L+ TP G +G++V+VWEL+
Sbjct: 3170 DQLTGLSLLPLSEKAARARQ--EELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3227
Query: 4597 REVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAE-AGSPRPDPREAL-- 4653
+ ++RQ+LL ++R G +TVE++ L +++ + + + +G P P L
Sbjct: 3228 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3287
Query: 4654 -----RAATMEVKVGR---------------LRGRA-------------VPVWDVLASGY 4680
RA ++K G+ L+G V +++ + G
Sbjct: 3288 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3347
Query: 4681 VSGAAREELL-AEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGR 4739
+ LL A+ +G L P +RL + EA +A P+L + E G
Sbjct: 3348 LRATTAALLLEAQAATGFLVDPVRNQRL--YVHEAVKAGVVGPELHEQLLSA-EKAVTGY 3404
Query: 4740 GDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQF----QGRPVSVWD 4795
D SG + Q A ++ +R ++ G V V
Sbjct: 3405 RDPYSGSTISLFQ---------AMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3455
Query: 4796 VLFSSYLSEARRDELLAQHAAGALGLPD--------LVAVLTRVIEETEERLSKVSFRGL 4847
Y SE + +LA + G D +L R +E+ E L + +G
Sbjct: 3456 AYQRGYFSE-EMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGA 3514
Query: 4848 RRQ--VSASELHTSGILG---PETLRDLAQG------TKTLQEVTEMDSVK--------- 4887
+ V ++++T ET D+ G T +L EV + D +
Sbjct: 3515 EKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMA 3574
Query: 4888 -----RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFV 4942
R + I + + K + RQ+ ++ Y V R TA L EA+ +
Sbjct: 3575 DFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDY----VRRRLTAEDLFEARIISLET 3630
Query: 4943 IDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 5002
+ +R S+ EA+ A E L +V G P + Q +S++QA++K L+
Sbjct: 3631 YNLLREGTRSLREALEA-----ESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSA 3685
Query: 5003 EHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTH 5062
E LLEAQ ATG ++DPV R+ VD A R+G E++ L G+ DP T
Sbjct: 3686 EVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTE 3745
Query: 5063 ENLTYLQLLQRATLDPETGLLFLSLSL 5089
+ ++ Q +++ + E L L L
Sbjct: 3746 QTISLFQAMKKELIPTEEALRLLDAQL 3772
Score = 347 bits (889), Expect = 2e-94
Identities = 202/360 (56%), Positives = 242/360 (67%), Gaps = 25/360 (6%)
Query: 4746 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 4801
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2502 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2561
Query: 4802 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 4848
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2562 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2618
Query: 4849 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 4908
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2619 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2675
Query: 4909 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 4968
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2676 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2733
Query: 4969 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 5028
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2734 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2793
Query: 5029 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLS 5088
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLL+R DPETGL L L+
Sbjct: 2794 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2853
Score = 254 bits (648), Expect = 2e-66
Identities = 137/307 (44%), Positives = 206/307 (67%), Gaps = 8/307 (2%)
Query: 4784 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE--ERLSK 4841
G G +S+W+V+ S + E +R +L+A AG + ++ ++ +IE+TE +
Sbjct: 3546 GSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGL 3605
Query: 4842 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 4901
S+ +RR+++A +L + I+ ET L +GT++L+E E +S YL GT +AGV +
Sbjct: 3606 ASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYL 3665
Query: 4902 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 4961
P G ++ +SIYQA+ KG+L A +LLEAQAATGF++DPV+ RL+V+EAV G+
Sbjct: 3666 P-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGL 3720
Query: 4962 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 5021
VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI E +RLL+AQ+ATGG++DP
Sbjct: 3721 VGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDP 3780
Query: 5022 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETG 5081
+P++VAY+RGY +++ + L++PS + + + DP+T E L+Y QLL+R D TG
Sbjct: 3781 RLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQLLRRCRRDDGTG 3839
Query: 5082 LLFLSLS 5088
L L LS
Sbjct: 3840 QLLLPLS 3846
Score = 107 bits (267), Expect = 3e-22
Identities = 73/212 (34%), Positives = 111/212 (52%), Gaps = 5/212 (2%)
Query: 4347 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4406
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4233 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4287
Query: 4407 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 4466
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4288 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4347
Query: 4467 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 4526
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4348 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4407
Query: 4527 THENLTYVQLLRRCVPDPDTGLYMLQLAGRGS 4558
T ++Y L R + + TGL +L+ A + +
Sbjct: 4408 TKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4439
Score = 107 bits (266), Expect = 4e-22
Identities = 73/210 (34%), Positives = 109/210 (51%), Gaps = 5/210 (2%)
Query: 4881 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4940
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4233 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4287
Query: 4941 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 5000
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4288 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4347
Query: 5001 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 5060
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4348 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4407
Query: 5061 THENLTYLQLLQRATLDPETGLLFLSLSLQ 5090
T ++Y L R+ ++ TGL L + Q
Sbjct: 4408 TKLKISYKDALDRSMVEEGTGLRLLEAAAQ 4437
Score = 105 bits (261), Expect = 2e-21
Identities = 69/217 (31%), Positives = 114/217 (52%), Gaps = 3/217 (1%)
Query: 13 GTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQ 72
G++S+ S P L + + P + +AG+ + + S+ AM + L+ GQ
Sbjct: 4219 GSSSSYPIS-PAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQ 4277
Query: 73 ALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLA 132
LLEAQA TGG++D + G+ PV+ A+ +GLV + +++ A++A G+ DP K++
Sbjct: 4278 RLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMS 4337
Query: 133 LFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLLDRETWHKLSELE 192
QA+ K + GQ +LEVQ TGGL++P V + A +G +D T KL ++
Sbjct: 4338 AAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV- 4396
Query: 193 PGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALL 229
G P T +++Y L+R + G+GL LL
Sbjct: 4397 -GAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4432
Score = 70.5 bits (171), Expect = 4e-11
Identities = 61/227 (26%), Positives = 102/227 (44%), Gaps = 17/227 (7%)
Query: 4832 IEETEERLS--KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 4889
++ T+ERLS + +G+ R +A EL + + + T++E M V
Sbjct: 3908 VDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPE 3967
Query: 4890 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 4949
+ A V P + +S++QAM KG++ + LLEAQ ATG +IDP +
Sbjct: 3968 FKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESH 4027
Query: 4950 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 5009
RL VE A G+ E+ E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4028 RLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLL 4087
Query: 5010 -------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 5041
E + ++ ++DP + V AYR+G D +
Sbjct: 4088 PLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4134
Score = 60.8 bits (146), Expect = 3e-08
Identities = 32/119 (26%), Positives = 61/119 (51%)
Query: 4971 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 5030
L ++ G T +++S++ A+Q+ L+ + LLEAQ A+G ++DPV + R+ V+
Sbjct: 2660 LQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVN 2719
Query: 5031 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSL 5089
A + G E++ L G+ DP T + ++ Q +Q+ + E G+ L +
Sbjct: 2720 EAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQI 2778
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4254 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4310
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4168 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4223
Query: 4311 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4359
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4224 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4283
Query: 4360 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4386
+C G++ P+ + P + KMS QA+
Sbjct: 4284 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4343
Query: 4387 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4446
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4344 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4403
Query: 4447 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 4487
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4404 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4445
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4788 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4844
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4168 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4223
Query: 4845 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4893
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4224 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4283
Query: 4894 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4920
+C G++ P+ + P + KMS QA+
Sbjct: 4284 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4343
Query: 4921 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4980
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4344 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4403
Query: 4981 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 5021
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4404 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4445
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 1268 bits (3280), Expect = 0.0
Identities = 798/1967 (40%), Positives = 1134/1967 (57%), Gaps = 218/1967 (11%)
Query: 1511 AAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLEGG 1570
AAE +P + +F GLR++VSA+ L A ++S + L L+QG TTV E+A + V+ L+G
Sbjct: 2774 AAEAEP-EHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGR 2832
Query: 1571 NFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFK 1630
+ IAG+L++ T E++S+ AL+R +L PGTAL+LLEAQAA+GF++DP NR+LTV EA K
Sbjct: 2833 SSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVK 2892
Query: 1631 AGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGI 1690
G+ G E + KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGG+
Sbjct: 2893 EGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGV 2952
Query: 1691 IDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 1750
IDPVHSHRVPVDVAYR GYFDEEMNR+LADPSDDTKGFFDPNTHENLTYLQLLERCVEDP
Sbjct: 2953 IDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 3012
Query: 1751 ETGLYLLQI---IKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTE 1807
ETGL LL + KG VY + R V + T G+F + V+ W++++S YFT
Sbjct: 3013 ETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTA 3072
Query: 1808 DRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLFNSRVIDQ 1867
+++R+L++++ +EK+++II T +EE E Q + +R V AA+L SRVID+
Sbjct: 3073 EQRRDLLRQFRTGRITVEKIIKIIITVVEEQE-QKGRLCFEGLRSLVPAAELLESRVIDR 3131
Query: 1868 KTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFA 1927
+ L+ G + ++ ++ V+ L G++ IAGV + + +S++ A +K+L+P+ A
Sbjct: 3132 ELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMA 3191
Query: 1928 TWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTI 1987
LLEAQA TG ++DP T +L+VDEAV GLV E E+LL AE+A TGYRDP TG ++
Sbjct: 3192 VALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSV 3251
Query: 1988 PLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQ 2047
LFQA++K LI + + LRLL+ Q++TGG++DP HR+PL+ A RGCL ++ +S
Sbjct: 3252 SLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAP 3311
Query: 2048 KHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVN-KAAR---DSEHIDDETRRAL 2103
+ K + DP+T E +Y ELQ+RCRP + TG L P++ KAAR + + + + R
Sbjct: 3312 RADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETF 3371
Query: 2104 EAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIE 2163
E VE+ VG F+G+ T+W L++SEY T E++ +L+R +RT + ++ V ++++ ++E
Sbjct: 3372 EKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRT-GKVTVEKVIKILITIVE 3430
Query: 2164 KQET-SNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEG 2222
+ ET + L F G+R + ASELL+S +++ + L+ G++T ++L E V+ L+G
Sbjct: 3431 EVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQG 3490
Query: 2223 TSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLS 2282
+ C+AG+ + +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL
Sbjct: 3491 SGCLAGIYL-----EDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLY 3545
Query: 2283 VEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQ 2342
V E V AGVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQ
Sbjct: 3546 VHEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQ 3605
Query: 2343 IATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLR 2402
IATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL
Sbjct: 3606 IATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLE 3665
Query: 2403 RCVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVW 2455
RCV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+W
Sbjct: 3666 RCVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLW 3725
Query: 2456 ELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAE 2503
E++ + E++R L++ ++AG +T E + + ++ + + + R
Sbjct: 3726 EVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLT 3785
Query: 2504 A----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWD 2538
A EA + LR T ++ G + G +P ++
Sbjct: 3786 AEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQ 3845
Query: 2539 VLASGYVS-RAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDARRGPRE 2597
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3846 ALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER 3903
Query: 2598 PGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSV 2657
A G D Q + +E A R + L + R F P+ V
Sbjct: 3904 ---AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV 3959
Query: 2658 WDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS------------- 2704
YL++ D+ L + V + V T+ERLS
Sbjct: 3960 --AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDG 4006
Query: 2705 ------------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKR 2752
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ ++++
Sbjct: 4007 TGQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQK 4064
Query: 2753 YLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 2812
+LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++
Sbjct: 4065 FLEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKG 4119
Query: 2813 LRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRL 2872
L+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRL
Sbjct: 4120 LKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRL 4179
Query: 2873 LEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYV 2932
LEAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+
Sbjct: 4180 LEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYL 4239
Query: 2933 QLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELL 2992
QL+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4240 QLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE-- 4293
Query: 2993 FYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALR 3052
YR G + + T L Q E S
Sbjct: 4294 ---------------AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------D 4324
Query: 3053 AATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEA 3112
+ + R GR + D +A + +A L ++ +GTL + L+
Sbjct: 4325 GVVKSMIIDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS------ 4374
Query: 3113 EEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTL 3172
G++G + G + + A +R Q +
Sbjct: 4375 ---------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASW 4407
Query: 3173 RDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVA 3224
D T E G G VS+ + + + + LL AQ G +
Sbjct: 4408 SDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI------- 4458
Query: 3225 VLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQE 3277
+ T ER ++ +GL ++ ++ + G P T ++ +
Sbjct: 4459 ----IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKG 4514
Query: 3278 VTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 3337
++ +R+LE G++ P D PGR + + +A+ +G + TA L + A +
Sbjct: 4515 WLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYS 4569
Query: 3338 GFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3383
++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4570 KYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4616
Score = 1127 bits (2914), Expect = 0.0
Identities = 724/1911 (37%), Positives = 1065/1911 (55%), Gaps = 110/1911 (5%)
Query: 522 EQRAMLAQQYQEGTLSVEKL-AAELSAT---------LEQAAATARV--TFSGLRDTVTP 569
EQ +L +Q++ E++ A++++AT L+ AA A +F GLR V+
Sbjct: 2733 EQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSA 2792
Query: 570 GELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEA 629
L +A I+ + +RL G T ++ + YLQG IAGLLL + E+LS+Y A
Sbjct: 2793 QRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAA 2852
Query: 630 RCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVT 689
+ LL PGTALILLEAQAA+GF++DP N+ +V EA++ V+GP++ KLLSAERAVT
Sbjct: 2853 LQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVT 2912
Query: 690 GYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 749
GY DPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF
Sbjct: 2913 GYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 2972
Query: 750 DQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSP----- 804
D+ +N +L DPSDDTKGFFDPNTHENLTYLQLLERCV DPETGL LLPL+ +
Sbjct: 2973 DEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELV 3032
Query: 805 LVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQV 864
DS + F+ +S +G+FQG+ V+ WE+INSEYF+ +RR LLR++R +T+ ++
Sbjct: 3033 YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKI 3092
Query: 865 AKLLEA---ETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDG 921
K++ E +++ + LRS V +LLE+ +ID++L Q+ G S + +D
Sbjct: 3093 IKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDT 3152
Query: 922 VRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPES 981
VRR L G + GV L +GQ+LS+Y A+++ LL +A+ALLEAQA TG I+DP +
Sbjct: 3153 VRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSAR 3212
Query: 982 LSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLE 1041
L+VDEAVR G+VGPE + +L AE A+ G+RDP++G+ VS+FQA+KKGLIP EQ RLL+
Sbjct: 3213 LTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLD 3272
Query: 1042 AQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSS---SSETFPTPDGQGRTSYAQL 1098
AQ++TGGI+DP+ H +P+ VA RG +D+E ALS+ ++ + P +Y +L
Sbjct: 3273 AQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGEL 3332
Query: 1099 LEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQA------------VPGAKDGT-SLW 1145
+ C D+ +GL LLPL E A A +E++ LQA V G K T ++W
Sbjct: 3333 QQRCRPDQLTGLSLLPLSEKA-ARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVW 3391
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+SS +FT EQR+ LL + G+ TV +++ + V+E + L Q R+ G R VPA
Sbjct: 3392 ELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPA 3451
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQA 1265
LL +G++++ E L G + ++E +V+ L G+GC+AG+ L+ + K SI +A
Sbjct: 3452 SELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEA 3511
Query: 1266 VRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAA 1325
+R GLL LLEAQ A+GFLVDP+ NQRL V +AVK G+VG EL EQL AE+A
Sbjct: 3512 MRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVT 3571
Query: 1326 GYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLL 1385
GY DPYS +++SL+QAM+KGLV + G+ LL+ Q+ATGG++DPVH +P A + G
Sbjct: 3572 GYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYF 3631
Query: 1386 DTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDH 1445
+ ++VL D K FFDP+ + +TY+QL ERCV D ETGL LLPL EV +
Sbjct: 3632 SEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVET 3691
Query: 1446 TAV--------ALRAMKVPV-STGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAA 1496
T V A ++ + G G ++SLW+++ S+ + ++R +L+A ++GR
Sbjct: 3692 TQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVT 3751
Query: 1497 ALRQVVSAVTALVEAAE--RQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTV 1554
R ++ + ++E E RQ A++ +R++++A DLF A++IS +T + L +GT ++
Sbjct: 3752 KERMII-IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSL 3810
Query: 1555 KEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFI 1614
+E E +S L G +AGV + G+++ +SI +AL++ +L A +LLEAQAATGF+
Sbjct: 3811 REALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFL 3870
Query: 1615 IDPAENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 1674
+DP + +LTV+EA + G+ G E + +LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3871 LDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPT 3930
Query: 1675 EHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTH 1734
E +RLL+AQ+ATGGI+DP +P++VAY+ GY +++ + L++PS+ + + DP+T
Sbjct: 3931 EEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSE-VRSYVDPSTD 3989
Query: 1735 ENLTYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVV 1794
E L+Y QLL RC D TG LL + A+ R + +
Sbjct: 3990 ERLSYTQLLRRCRRDDGTGQLLLPL--------------------SDARKLTFRGLRKQI 4029
Query: 1795 SFWDLLSSPYFTED---RKRELIQEYGAQSGGLEKLLE-------IITTTIEETETQNQG 1844
+ +L+ S E + RE + + L+K LE + +E + Q
Sbjct: 4030 TMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQA 4089
Query: 1845 IKVAAIRG----EVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIA 1900
+K IR E+ A VID L V + E L +
Sbjct: 4090 MKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVT 4149
Query: 1901 GVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLV 1960
G P + +++SL +A +K LI LLEAQ ATG ++DP +L V+ A GL
Sbjct: 4150 GYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLF 4209
Query: 1961 NEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLL------------- 2007
+EE+ E L G+ DP T + + Q M++ + + L LL
Sbjct: 4210 DEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSS 4269
Query: 2008 --EVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSY 2065
V+ ++DP+ + + AYR+G + Y +S+Q+ + ++ V
Sbjct: 4270 KSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKS 4329
Query: 2066 RELQERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALE----AEQVEITVGRFRGQKPT 2121
+ R Q D + + K D +D L A+ + G FR + +
Sbjct: 4330 MIIDRRSGRQYD---IDDAIAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSS 4386
Query: 2122 LWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQI 2181
+ + + + QL + T L E +EK S + + I
Sbjct: 4387 VGSSSSYPISPAVSRTQLA-SWSDPTEETGPVAGILDTETLEK--VSITEAMHRNLVDNI 4443
Query: 2182 TASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQE 2241
T LL + T ++ R + + V + + +A + P +
Sbjct: 4444 TGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKT 4503
Query: 2242 KMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLL 2301
KMS QA+ KG L LE Q TG +I+P R+ ++E + G V + +KL
Sbjct: 4504 KMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLR 4563
Query: 2302 SAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 2351
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4564 DVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4614
Score = 1054 bits (2725), Expect = 0.0
Identities = 630/1557 (40%), Positives = 924/1557 (59%), Gaps = 83/1557 (5%)
Query: 869 EAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCG 928
EAE + D LR +V+ +L EAGI+ + L ++ G + + L + VR YL G
Sbjct: 2776 EAEPEHSFD----GLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQG 2831
Query: 929 LGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAV 988
++ G+ L + ++LS+Y A++++LL P AL LLEAQAA+G ++DP L+V+EAV
Sbjct: 2832 RSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAV 2891
Query: 989 RRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGG 1048
+ GVVGPEL+ +L AE A+ G++DP++G+Q+S+FQAM+KGLI E RLLEAQ+ATGG
Sbjct: 2892 KEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGG 2951
Query: 1049 IIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRD 1105
+IDP H +P+ VA +RGY D+EM L+ S+ F P+ +Y QLLE C D
Sbjct: 2952 VIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVED 3011
Query: 1106 ETSGLHLLPLPESAPA--------LPTEEQVQRSLQAVPGAK---DGTSLWDLLSSCHFT 1154
+GL LLPL + A + +++ + P K ++W++++S +FT
Sbjct: 3012 PETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFT 3071
Query: 1155 EEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDAGII 1214
EQRR LL + GR TV +++ + V+E + + R+ G R VPA LL++ +I
Sbjct: 3072 AEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE--QKGRLCFEGLRSLVPAAELLESRVI 3129
Query: 1215 TQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTG 1274
+E + L +G +S VAE V+ L G +AGV L+ +G K SI A++ LLP+
Sbjct: 3130 DRELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSD 3189
Query: 1275 LGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRA 1334
+ LLEAQ +G ++DP + RL+V++AV+ GLVG E E+L AE+A GY DPY+
Sbjct: 3190 MAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQ 3249
Query: 1335 SLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLT 1394
S+SL+QA++KGL+P+ +GL LL QL+TGG+VDP +P AC G LD +TS+ L+
Sbjct: 3250 SVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALS 3309
Query: 1395 AVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMK 1454
A D K + DPS + TY +L++RC D TGL LLPL + L+A +
Sbjct: 3310 APRADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARE 3369
Query: 1455 ------VPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVTAL 1508
V V G FKG +V++W+L+ SEY A++R+EL+ R+G+ + + +T +
Sbjct: 3370 TFEKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIV 3429
Query: 1509 VEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
E + + +F GLR V A +L + ++SR ++L G TTVK+++E+ SV+ L+
Sbjct: 3430 EEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQ 3489
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G +AG+ ++ T+E++SI EA+RR +LR TA +LLEAQAATGF++DP N++L V EA
Sbjct: 3490 GSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEA 3549
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 1688
KAG+ G E + +LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATG
Sbjct: 3550 VKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATG 3609
Query: 1689 GIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVE 1748
GIIDPVHSHRVPVDVAY+ GYF EEMNR+LADPSDDTKGFFDPNTHENLTY QLLERCVE
Sbjct: 3610 GIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVE 3669
Query: 1749 DPETGLYLLQI--IKKGE----NYVYINEATRHVLQSRTAKM-RVGRFADQVVSFWDLLS 1801
DPETGL LL + +K E VY E TR + + G +S W+++
Sbjct: 3670 DPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQ 3729
Query: 1802 SPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETE-TQNQGI-KVAAIRGEVTAADL 1859
S E+++ +L+ ++ A E+++ II IE+TE + QG+ +R +TA DL
Sbjct: 3730 SDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDL 3789
Query: 1860 FNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRK 1919
F +R+I +T + LR G + E YL G+ +AGV +P +R+ +S+++A +K
Sbjct: 3790 FEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKK 3849
Query: 1920 ELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYR 1979
L+ A A LLEAQAATGFLLDP ++L+VDEAV GLV EL +RLL AERA TGYR
Sbjct: 3850 GLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYR 3909
Query: 1980 DPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKD 2039
DP T TI LFQAM+K+LI EALRLL+ Q+ATGG++DP+ LPLE AY+RG L+KD
Sbjct: 3910 DPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKD 3969
Query: 2040 IYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDET 2099
+ +S+ +R +VDP+T E++SY +L RCR + TG +L P++ A + +
Sbjct: 3970 THDQLSEPSEVRS-YVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT------- 4021
Query: 2100 RRALEAEQVEITVGRFRG--QKPTLWALLNSEYVTEEKKLQL------VRMYRTHTRRAL 2151
FRG ++ T+ L+ S+ + E LQL + + ++ L
Sbjct: 4022 ---------------FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFL 4066
Query: 2152 QTVAQLILELIE--KQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQE 2209
+ + + ++ K+ S +GI R TA ELL + T ++ ++ + T +E
Sbjct: 4067 EGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 4126
Query: 2210 LMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 2269
+ V + A V P + +S++QAM KG++ + LLEAQ AT
Sbjct: 4127 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4186
Query: 2270 GFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDL 2329
G +IDP + RL VE G+ E+ E L G+ DP T + ++ Q M++ +
Sbjct: 4187 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4246
Query: 2330 IVREHGIRLL-------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 2371
+ G+ LL E + ++ ++DP + V AYR+G D +
Sbjct: 4247 TDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4303
Score = 999 bits (2583), Expect = 0.0
Identities = 666/1843 (36%), Positives = 989/1843 (53%), Gaps = 126/1843 (6%)
Query: 234 TFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLL 293
+F + VSA L E GIL + +Q L +G +++ R +VR YL+G S+AG++L
Sbjct: 2782 SFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLK 2841
Query: 294 PEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELH 353
K S + A LL GTAL LLEAQAA+ L+DP+ +RL V+EAV+ G+V PELH
Sbjct: 2842 ATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELH 2901
Query: 354 EQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRL 413
+LL AE+AVTG+ DP++G QI LFQAM+KGL+ R +RLL+AQ+ATGG++ P R+
Sbjct: 2902 HKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRV 2961
Query: 414 PLEAALRCGCLDEDTQRQLSQA-----GSFSDGTHGGLRYEQLLALCVTDPETGLAFLPL 468
P++ A R G DE+ R L+ G F TH L Y QLL CV DPETGL LPL
Sbjct: 2962 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPL 3021
Query: 469 SG-GPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAML 527
+ +GGE + R AT + GKF+G+ V++WE++ SE ++EQR L
Sbjct: 3022 TDKAAKGGELV---YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDL 3078
Query: 528 AQQYQEGTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLE 587
+Q++ G ++VEK+ + +E+ R+ F GLR V ELL++ +ID++LY++L+
Sbjct: 3079 LRQFRTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQ 3138
Query: 588 HGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQ 647
G+ + +DV + + +R L+G IAG+ L + ++LSIY A K LL A+ LLEAQ
Sbjct: 3139 RGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQ 3198
Query: 648 AATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQ 707
A TG IIDP + +V+EA+RA ++GP+ KLLSAE+AVTGY DPYTGQ +SLFQA++
Sbjct: 3199 AGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALK 3258
Query: 708 KGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGF 767
KGLI RE G+RLL+AQ++TGG++DP SHRVP+DVA RG D+ + L P D K +
Sbjct: 3259 KGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAY 3318
Query: 768 FDPNTHENLTYLQLLERCVRDPETGLYLLPLS-----STQSPLV-DSATQQAFQNLLLSV 821
DP+T E TY +L +RC D TGL LLPLS + Q L + ++ F+ + V
Sbjct: 3319 SDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEV 3378
Query: 822 KYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQVAKLL-----EAETQRQA 876
G F+G+ V+ WELI+SEYF+ +R++LLR++R +VT+ +V K+L E ET RQ
Sbjct: 3379 PVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQE 3438
Query: 877 DIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVR 936
+ LR+ V +LL +G++ + +Q+ G + + L + VR L G G + G+
Sbjct: 3439 RLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIY 3498
Query: 937 LLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPE 996
L + +++S+Y+AMR+ LL A LLEAQAATG ++DP + L V EAV+ GVVGPE
Sbjct: 3499 LEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPE 3558
Query: 997 LYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHH 1056
L+ +L AE A+ G+RDP+SG +S+FQAM+KGL+ + RLLEAQ+ATGGIIDP H
Sbjct: 3559 LHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSH 3618
Query: 1057 HLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRDETSGLHLL 1113
+P+ VA QRGY +EM L+ S+ F P+ +Y QLLE C D +GL LL
Sbjct: 3619 RVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLL 3678
Query: 1114 PLPESAPA-------LPTEEQVQRSLQA----VPG----AKDGTSLWDLLSSCHFTEEQR 1158
PL + A + TEE+ +R+ + +PG SLW+++ S EEQR
Sbjct: 3679 PLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQR 3738
Query: 1159 RGLLEDVQEGRTTVPQLLASVQRWVQETKLL-AQARVMVPGPRGEVPAVWLLDAGIITQE 1217
L+ D Q GR T +++ + +++T+++ Q R + A L +A II+ E
Sbjct: 3739 AQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLE 3798
Query: 1218 TLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQ 1277
T L +GT+S + E + L+GTG VAGV L S SI QA++ GLL + +
Sbjct: 3799 TYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVAR 3858
Query: 1278 RLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLS 1337
LLEAQ A+GFL+DP+ +RL+V++AV+ GLVG EL ++L AERA GY DPY+ ++S
Sbjct: 3859 LLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTIS 3918
Query: 1338 LWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVD 1397
L+QAM+K L+P E L LL QLATGG+VDP G HLP A + G L+ T L+
Sbjct: 3919 LFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSE-P 3977
Query: 1398 KDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPV 1457
+ + + DPS ++++Y QL RC D TG LLLPL D + R ++ +
Sbjct: 3978 SEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPL--------SDARKLTFRGLRKQI 4029
Query: 1458 STGRFKGCSVSLWDLLLSEYVGADKRRELVALCR-SGRAAALRQVVSAVTALVEAAERQP 1516
+ V + E R L ++ + + S + + A ++
Sbjct: 4030 TMEELVRSQV------MDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKER 4083
Query: 1517 L---QATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSV-----KRSLE 1568
L QA +G+ + +A +L AQ + +D + TV+E M V + L
Sbjct: 4084 LSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLS 4143
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
+ G + + +S+ +A+++ ++ + LLEAQ ATG IIDP E+ +L VE A
Sbjct: 4144 AERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVA 4203
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL------- 1681
+K G+F +E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4204 YKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKR 4263
Query: 1682 EAQIATGG--------IIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNT 1733
E + ++ I+DP + V AYR G D +
Sbjct: 4264 ERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ-------------------- 4303
Query: 1734 HENLTYLQLLERCVEDPE------TGLYLLQIIKKGENYVY-INEATRHVLQSRTAKMRV 1786
TYL+L E+ E E G+ II + Y I++A L R+A +
Sbjct: 4304 ----TYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRSALDQY 4359
Query: 1787 GRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIK 1846
+ F D+LS R G+ S T ++ +
Sbjct: 4360 RAGTLSITEFADMLSG---NAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGP 4416
Query: 1847 VAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPS 1906
VA I T +V + +H V GQ L LE C G+ PS
Sbjct: 4417 VAGILDTETL-----EKVSITEAMHRNLVDNITGQRL---------LEAQACTGGIIDPS 4462
Query: 1907 TREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRE 1966
T E + +A K L+ + AQ A DP T+ K+S +A+ G + E +
Sbjct: 4463 TGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQ 4522
Query: 1967 RLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEV 2009
R L+ + G +P T +PL +A+Q+ ++ A +L +V
Sbjct: 4523 RFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV 4565
Score = 970 bits (2508), Expect = 0.0
Identities = 547/1287 (42%), Positives = 810/1287 (62%), Gaps = 33/1287 (2%)
Query: 1155 EEQRRGLL---EDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDA 1211
EEQ R L E+V + + L + + + A+ G R +V A L +A
Sbjct: 2739 EEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEA 2798
Query: 1212 GIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLL 1271
GI++ E L+ LAQG + ++A + V+ L G +AG+LL+ + K S+ A++ LL
Sbjct: 2799 GILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLL 2858
Query: 1272 PTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPY 1331
G LLEAQ ASGFL+DP+ N+RL+V +AVK G+VG EL +L AERA GY DPY
Sbjct: 2859 SPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPY 2918
Query: 1332 SRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQ 1391
+ +SL+QAM+KGL+ + G+ LL+ Q+ATGGV+DPVH +P A R G D + ++
Sbjct: 2919 TGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNR 2978
Query: 1392 VLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDT-----VLEVDDHT 1446
VL D K FFDP+ + +TY QL ERCV D ETGL LLPL ++ D
Sbjct: 2979 VLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEA 3038
Query: 1447 AVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVT 1506
V G+F+G +V++W+++ SEY A++RR+L+ R+GR + +++ +
Sbjct: 3039 RDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRIT-VEKIIKIII 3097
Query: 1507 ALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRS 1566
+VE E++ + F GLR V A +L +++I R+ +L +G +V++VAE+D+V+R+
Sbjct: 3098 TVVEEQEQKG-RLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 3156
Query: 1567 LEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVE 1626
L G N IAGV ++ +++SI AL++ +L A+ LLEAQA TG IIDPA + +LTV+
Sbjct: 3157 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVD 3216
Query: 1627 EAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIA 1686
EA +AG+ G E + KLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++
Sbjct: 3217 EAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLS 3276
Query: 1687 TGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERC 1746
TGGI+DP SHRVP+DVA G DEE +R L+ P D K + DP+T E TY +L +RC
Sbjct: 3277 TGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRC 3336
Query: 1747 VEDPETGLYLLQIIKKG----ENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSS 1802
D TGL LL + +K + +Y R + ++ VG F + V+ W+L+SS
Sbjct: 3337 RPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3396
Query: 1803 PYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQG-IKVAAIRGEVTAADLFN 1861
YFT ++++EL++++ +EK+++I+ T +EE ET Q + + +R V A++L
Sbjct: 3397 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3456
Query: 1862 SRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKEL 1921
S V+ + L+ G+T + LS L V+ L+GS C+AG+ + T+E +S++EA R+ L
Sbjct: 3457 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3516
Query: 1922 IPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDP 1981
+ A A LLEAQAATGFL+DP Q+L V EAV G+V EL E+LL AE+A TGYRDP
Sbjct: 3517 LRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDP 3576
Query: 1982 ATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIY 2041
+G TI LFQAMQK L+ + +RLLE Q+ATGG+IDP H HR+P++ AY+RG +++
Sbjct: 3577 YSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMN 3636
Query: 2042 ALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSE-------H 2094
+++D K F DPNT E ++YR+L ERC +TG L P+ K A +E +
Sbjct: 3637 RVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL-KGAEKAEVVETTQVY 3695
Query: 2095 IDDETRRALEAEQVEITVGRFRGQKP-TLWALLNSEYVTEEKKLQLVRMYRTHTRRALQT 2153
++ETRRA E Q++I G G +LW ++ S+ + EE++ QL+ ++ R +
Sbjct: 3696 TEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAG-RVTKER 3754
Query: 2154 VAQLILELIEKQETSNKH--LWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELM 2211
+ +I+E+IEK E + + +RR++TA +L + II+ E L G + +E +
Sbjct: 3755 MIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREAL 3814
Query: 2212 EDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGF 2271
E + YL GT +AGV +P G ++ +SIYQA+ KG+L A +LLEAQAATGF
Sbjct: 3815 EAESAWCYLYGTGSVAGVYLP-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGF 3869
Query: 2272 VIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIV 2331
++DPV+ RL+V+E V G+VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3870 LLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIP 3929
Query: 2332 REHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNT 2391
E +RLL+AQ+ATGG++DP +P++VAY+RGY +++ + L++PS + + + DP+T
Sbjct: 3930 TEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPST 3988
Query: 2392 HENLTYVQLLRRCVPDPDTGLYMLQLA 2418
E L+Y QLLRRC D TG +L L+
Sbjct: 3989 DERLSYTQLLRRCRRDDGTGQLLLPLS 4015
Score = 881 bits (2277), Expect = 0.0
Identities = 629/1746 (36%), Positives = 913/1746 (52%), Gaps = 133/1746 (7%)
Query: 41 RSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQ 100
R++ G +GQ S++ AM++GL+ G LLEAQ ATGG++D +PV A +
Sbjct: 2909 RAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR 2968
Query: 101 QGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEV--QLATG 158
+G E+ L T G+ DP E L Q + + V D G L + + A G
Sbjct: 2969 RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKG 3028
Query: 159 GLV----DPAQGVLVAPEPACHQGLLDRET---WHKLSELEPGTGDLR--FLNPNTLERL 209
G + A+ V + G +T W ++ E T + R L R+
Sbjct: 3029 GELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINS-EYFTAEQRRDLLRQFRTGRI 3087
Query: 210 TYHQLLERCVRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAV 269
T ++++ + ++ F + V AAELLE ++D + Q L+ G +
Sbjct: 3088 TVEKIIKIIITVVEEQEQ--KGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVR 3145
Query: 270 DVSARAEVRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLV 329
DV+ VRR L G +AGV L G K S + A + LLP A+ LLEAQA T ++
Sbjct: 3146 DVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHII 3205
Query: 330 DPITGQRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRP 389
DP T RL VDEAVRAGLV PE HE+LL AE+AVTG+ DP++G + LFQA+KKGL+ R
Sbjct: 3206 DPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPRE 3265
Query: 390 LALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLS----QAGSFSDGTHGG 445
LRLLDAQL+TGG+V P++ R+PL+ A GCLDE+T R LS A ++SD + G
Sbjct: 3266 QGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGE 3325
Query: 446 -LRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFR 504
Y +L C D TGL+ LPLS Q + + R+ V VG F+
Sbjct: 3326 PATYGELQQRCRPDQLTGLSLLPLSEKAARAR-QEELYSELQARETFEKTPVEVPVGGFK 3384
Query: 505 GRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAELSATLEQAAATA--RVTFSG 562
GR V++WEL+ SE ++EQR L +Q++ G ++VEK+ L +E+ R++FSG
Sbjct: 3385 GRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSG 3444
Query: 563 LRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQE 622
LR V ELL + ++ + +E+L+ G+ T KD+ L S + LQG+GC+AG+ L ++E
Sbjct: 3445 LRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKE 3504
Query: 623 RLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLL 682
++SIYEA +GLLR TA +LLEAQAATGF++DP N+ V EA++A V+GP++ +LL
Sbjct: 3505 KVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLL 3564
Query: 683 SAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDV 742
SAE+AVTGY DPY+G ISLFQAMQKGL++R+HGIRLLEAQIATGG+IDPVHSHRVPVDV
Sbjct: 3565 SAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3624
Query: 743 AYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQ 802
AY+RGYF + +N +L DPSDDTKGFFDPNTHENLTY QLLERCV DPETGL LLPL +
Sbjct: 3625 AYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAE 3684
Query: 803 SPLV--------DSATQQAFQNLLLSVK-YGRFQGQRVSAWELINSEYFSEGRRRQLLRR 853
V + T++AF+ + + G G +S WE++ S+ E +R QL+
Sbjct: 3685 KAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMAD 3744
Query: 854 YRQREVTLGQVAKLL-----EAETQRQADI-MLPALRSRVTVHQLLEAGIIDQQLLDQVL 907
++ VT ++ ++ + E RQ + +R R+T L EA II + + +
Sbjct: 3745 FQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLR 3804
Query: 908 AGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQ 967
GT S L + YL G G+V GV L S Q LS+YQA+++ LL VA LLEAQ
Sbjct: 3805 EGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQ 3864
Query: 968 AATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMK 1027
AATG ++DP E L+VDEAVR+G+VGPEL+ RL AE A+ G+RDP++ + +S+FQAMK
Sbjct: 3865 AATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMK 3924
Query: 1028 KGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSE--TFP 1085
K LIP E+A RLL+AQ+ATGGI+DP HLP+ VA QRGY++++ LS SE ++
Sbjct: 3925 KELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYV 3984
Query: 1086 TPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGTSLW 1145
P R SY QLL C RD+ +G LLPL ++ R L G + ++
Sbjct: 3985 DPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDA-----------RKL-TFRGLRKQITME 4032
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+ S E L +EG T++ ++ ++Q++++ T + A V V + +
Sbjct: 4033 ELVRSQVMDEATALQL----REGLTSIEEVTKNLQKFLEGTSCI--AGVFVDATKERLSV 4086
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAE---------QPAVKACLWG----------TG 1246
+ GII T L + + V + + AV+ + G
Sbjct: 4087 YQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAER 4146
Query: 1247 CVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKV 1306
V G SG S+ QA++ GL+ G RLLEAQ+A+G ++DP + RL VE A K
Sbjct: 4147 AVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKR 4206
Query: 1307 GLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLL---------- 1356
GL E++E L G+ DP + +L+ Q ME+ + GL LL
Sbjct: 4207 GLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERK 4266
Query: 1357 -----QVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQ 1411
V+ +VDP G + A R GL+D QT L+ + + ++
Sbjct: 4267 TSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECE---------WEE 4317
Query: 1412 VTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLW- 1470
+T D +++ S ++DD A L + +++ ++S+
Sbjct: 4318 ITISS------SDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRS---ALDQYRAGTLSITE 4368
Query: 1471 --DLLLSEYVGADKRRELVALCRS---GRAAALRQVVS---------AVTALVEAAERQP 1516
D+L G R V S A + Q+ S V +++ +
Sbjct: 4369 FADMLSGNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEK 4428
Query: 1517 L---QATFRGLRKQVSARDLFRAQ-----LISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
+ +A R L ++ + L AQ +I T + K + + V R
Sbjct: 4429 VSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINL 4488
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G T+ +MS +AL++ L LE Q TG +I+P ++ ++EA
Sbjct: 4489 AQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEA 4548
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-AT 1687
+ G T KL T P T +IS A+ + ++ G+RLLEA +T
Sbjct: 4549 LQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4608
Query: 1688 GGIIDP 1693
G P
Sbjct: 4609 KGYYSP 4614
Score = 869 bits (2246), Expect = 0.0
Identities = 711/2089 (34%), Positives = 1014/2089 (48%), Gaps = 390/2089 (18%)
Query: 2610 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 2665
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2671 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2730
Query: 2666 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 2712
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2731 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2787
Query: 2713 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 2772
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2788 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2844
Query: 2773 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 2832
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2845 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2902
Query: 2833 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2892
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2903 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2962
Query: 2893 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL- 2951
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L
Sbjct: 2963 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 3022
Query: 2952 --AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRY 3009
A +G + E R A V+ G QG++V++WE++ + ++R+DLL ++
Sbjct: 3023 DKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQF 3082
Query: 3010 RAGTLTVEELGATLTSLLAQAQAQAR----------AEAEAGSPRPDPREALR------- 3052
R G +TVE++ + +++ + + + R AE R RE +
Sbjct: 3083 RTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGER 3142
Query: 3053 ----AATMEVKVGRLRGRAV--PVWDVLASGYVS--GAAREELL----------AEFGSG 3094
A ++ LRG V VW A +S A +++LL A+ G+G
Sbjct: 3143 SVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTG 3202
Query: 3095 TLDLPALTRRLTAIIEEAEEAPGARPQL--------------QDAWRG------------ 3128
+ PA + RLT ++EA A P+ +D + G
Sbjct: 3203 HIIDPATSARLT--VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKG 3260
Query: 3129 --PREPG-------PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQ 3168
PRE G + G D +S R G + ET A +A A A
Sbjct: 3261 LIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSD 3320
Query: 3169 EQTLRDATM-EVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLT 3227
T AT E+Q+ + + + S + AR++EL ++ A
Sbjct: 3321 PSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------R 3368
Query: 3228 RVIEETEERLSKVSFRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV----- 3278
E+T + F+G R V+ EL +S E LR G T+++V
Sbjct: 3369 ETFEKTPVEVPVGGFKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILI 3426
Query: 3279 TEMDSVKRYLEGTSCIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALV 3329
T ++ V+ + +G+ VPA + + E++ + K + G+
Sbjct: 3427 TIVEEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRT 3486
Query: 3330 LLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP-------- 3381
LL+ + ++S+ EA+ G++ LL A+ A DP
Sbjct: 3487 LLQGSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYV 3546
Query: 3382 ------------------------------YTGQQISLFQAMQKDLIVREHGIRLLEAQI 3411
Y+G ISLFQAMQK L++R+HGIRLLEAQI
Sbjct: 3547 HEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQI 3606
Query: 3412 ATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRR 3471
ATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL R
Sbjct: 3607 ATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLER 3666
Query: 3472 CVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWE 3524
CV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+WE
Sbjct: 3667 CVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWE 3726
Query: 3525 LLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA 3572
++ + E++R L++ ++AG +T E + + ++ + + + R A
Sbjct: 3727 VMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTA 3786
Query: 3573 ----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDV 3607
EA + LR T ++ G + G +P ++
Sbjct: 3787 EDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQA 3846
Query: 3608 LASGYVSG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREP 3666
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3847 LKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER- 3903
Query: 3667 GPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVW 3726
A G D Q + +E A R + L + R F P+ V
Sbjct: 3904 --AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV- 3959
Query: 3727 DVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------- 3772
YL++ D+ L + V + V T+ERLS
Sbjct: 3960 -AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGT 4007
Query: 3773 -----------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 3821
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++
Sbjct: 4008 GQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKF 4065
Query: 3822 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 3881
LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L
Sbjct: 4066 LEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGL 4120
Query: 3882 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 3941
+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLL
Sbjct: 4121 KLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLL 4180
Query: 3942 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQ 4001
EAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+Q
Sbjct: 4181 EAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQ 4240
Query: 4002 LLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLF 4061
L+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4241 LMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYEA-- 4294
Query: 4062 YREVSEDRRQDL-LSRYRA--STLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREA 4118
YR+ D + L LS +T+ + S++
Sbjct: 4295 YRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMI----------------------- 4331
Query: 4119 LRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIE 4178
+ R GR + D +A + R+A L ++ +GTL + L+
Sbjct: 4332 ---------IDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS---- 4374
Query: 4179 EAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ 4238
G++G + G + + A +R Q
Sbjct: 4375 -----------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLA 4405
Query: 4239 TLRDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDL 4290
+ D T E G G VS+ + + + + LL AQ G +
Sbjct: 4406 SWSDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI----- 4458
Query: 4291 VAVLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTL 4343
+ T ER ++ +GL ++ ++ + G P T ++
Sbjct: 4459 ------IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4512
Query: 4344 QEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQA 4403
+ ++ +R+LE G++ P D PGR + + +A+ +G + TA L + A
Sbjct: 4513 KGWLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGA 4567
Query: 4404 ATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 4451
+ ++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4568 YSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4616
Score = 852 bits (2202), Expect = 0.0
Identities = 715/2192 (32%), Positives = 1042/2192 (47%), Gaps = 408/2192 (18%)
Query: 1960 VNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEAL----RLLEVQVATGG 2015
+ +E + LK+E T ++ +T QA+Q+ + + ++L R +E + A
Sbjct: 2599 LQQEAKLLQLKSEEMQTVQQEQLLQET----QALQQSFLSEKDSLLQRERFIEQEKAKLE 2654
Query: 2016 VI---DPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERC 2072
+ + +L E ++ + ++ L++ + R+R + + ELQ+
Sbjct: 2655 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2714
Query: 2073 RPQEDTGWVLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVT 2132
+ + +L N+ R+ + +E RA A E+T + K
Sbjct: 2715 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL----------- 2763
Query: 2133 EEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSAII 2192
+ R AL A E +H F G+RR+++A L + I+
Sbjct: 2764 ------------PNGRDALDGPA---------AEAEPEHS-FDGLRRKVSAQRLQEAGIL 2801
Query: 2193 TEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKG 2252
+ E LQ L G +T EL + V+ YL+G S IAG+L+ A + EK+S+Y A+ +
Sbjct: 2802 SAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN-----EKLSVYAALQRQ 2856
Query: 2253 VLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTD 2312
+L PGTAL+LLEAQAA+GF++DPVRN RL+V E V GVVG E+ KLLSAERAVTGY D
Sbjct: 2857 LLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKD 2916
Query: 2313 PYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2372
PYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM
Sbjct: 2917 PYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2976
Query: 2373 NRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL---AGRGSAVHQLSE 2429
NRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L A +G +
Sbjct: 2977 NRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDS 3036
Query: 2430 ELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATL 2489
E R A V+ G QG++V++WE++ + ++R+DLL ++R G +TVE++ +
Sbjct: 3037 EARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKII 3096
Query: 2490 TSLLAQAQAQAR----------AEAEAGSPRPDPREALR-----------AATMEVKVGR 2528
+++ + + + R AE R RE + A ++
Sbjct: 3097 ITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 3156
Query: 2529 LRGRAV--PVWDVLASGYVS--RAAREELL----------AEFGSGTLDLPALTRRLTAI 2574
LRG V VW A +S A +++LL A+ G+G + PA + RLT
Sbjct: 3157 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLT-- 3214
Query: 2575 IEEAEEAPGARPQ--------------------------LQDARRG--PREPG------- 2599
++EA A P+ Q ++G PRE G
Sbjct: 3215 VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQ 3274
Query: 2600 PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQEQTLRDATM-EVQR 2647
+ G D +S R G + ET A +A A A T AT E+Q+
Sbjct: 3275 LSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQ 3334
Query: 2648 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVS 2707
+ + + S + AR++EL ++ A E+T +
Sbjct: 3335 RCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------RETFEKTPVEVPVGG 3382
Query: 2708 FRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV-----TEMDSVKRYLEGTS 2758
F+G R V+ EL +S E LR G T+++V T ++ V+ +
Sbjct: 3383 FKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERL 3440
Query: 2759 CIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDP 2809
+G+ VPA + + E++ + K + G+ LL+ +
Sbjct: 3441 SFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLE 3500
Query: 2810 VRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP---------------------- 2847
++S+ EA+ G++ LL A+ A DP
Sbjct: 3501 DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELH 3560
Query: 2848 ----------------YTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRV 2891
Y+G ISLFQAMQK L++R+HGIRLLEAQIATGG+IDPVHSHRV
Sbjct: 3561 EQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRV 3620
Query: 2892 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL 2951
PVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+TGL +L L
Sbjct: 3621 PVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL 3680
Query: 2952 AGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYREVSEDRRQD 3004
G A EE R A + ++ PG G+ G ++S+WE++ + E++R
Sbjct: 3681 KGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQ 3740
Query: 3005 LLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EAGSPRPDPR 3048
L++ ++AG +T E + + ++ + + + R A EA +
Sbjct: 3741 LMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETY 3800
Query: 3049 EALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYVSG-AAREE 3086
LR T ++ G + G +P ++ L G +S AR
Sbjct: 3801 NLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLL 3860
Query: 3087 LLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQ 3146
L A+ +G L P RLT ++EA P+L D A G D Q
Sbjct: 3861 LEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTGYRDPYTEQ 3915
Query: 3147 REGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRD 3206
+ +E A R + L + R F P+ V YL++ D
Sbjct: 3916 TISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRGYLNKDTHD 3972
Query: 3207 ELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------------KVS 3241
+ L + V + V T+ERLS K++
Sbjct: 3973 Q-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT 4021
Query: 3242 FRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPA 3301
FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSCIAGV V A
Sbjct: 4022 FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSCIAGVFVDA 4079
Query: 3302 KDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVG 3361
+E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEEAV G+VG
Sbjct: 4080 -----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVG 4134
Query: 3362 GEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVH 3421
E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIATGG+IDP
Sbjct: 4135 PEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEE 4194
Query: 3422 SHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLY 3481
SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+QL+ RC+ DP TGL
Sbjct: 4195 SHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLC 4254
Query: 3482 MLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLS 3541
+L L + S+ R V P + G+ +SV+E
Sbjct: 4255 LLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE----------------- 4293
Query: 3542 RYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRA 3601
YR G + + T L Q E S + + R GR
Sbjct: 4294 AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------DGVVKSMIIDRRSGRQ 4339
Query: 3602 VPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWR 3661
+ D +A + +A L ++ +GTL + L+
Sbjct: 4340 YDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS--------------------- 4374
Query: 3662 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG- 3720
G++G + G + + A +R Q + D T E G G
Sbjct: 4375 ------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEET--GPVAGI 4420
Query: 3721 ------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVAVLTRVIEETEER--L 3771
VS+ + + + + LL AQ G + + T ER +
Sbjct: 4421 LDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI-----------IDPSTGERFPV 4469
Query: 3772 SKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTS 3826
+ +GL ++ ++ + G P T ++ + ++ +R+LE
Sbjct: 4470 TDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQY 4529
Query: 3827 CIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVE 3886
G++ P D PGR + + +A+ +G + TA L + A + ++ P L++S +
Sbjct: 4530 LTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYK 4584
Query: 3887 EAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3917
+A+ +V +LL +A ++ GY PY+
Sbjct: 4585 DALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4616
Score = 727 bits (1876), Expect = 0.0
Identities = 710/2292 (30%), Positives = 1038/2292 (45%), Gaps = 316/2292 (13%)
Query: 3017 EELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLAS 3076
EE+ A S A +A E E G R + + LR+ + ++ R R + +
Sbjct: 2062 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE-QAELEAARQRQLAAEEERRR 2120
Query: 3077 GYVSGAAREELLAEFGSGTLDLPAL--TRRLTAIIEEAE------EAPGARPQLQDAWRG 3128
++ L AE + AL RL A +EEA E AR QLQ A
Sbjct: 2121 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEA 2179
Query: 3129 PREPGPAGRGDGDSGRSQREGQGEGETQEAAAA-------AAAARRQEQTLRDATMEVQR 3181
++ A Q+E + + Q+ + A AARR + +A ++ +R
Sbjct: 2180 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2239
Query: 3182 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAV-LTRVIEETEERLSKV 3240
Q R + EA R + A+ A A A L + E+ R ++
Sbjct: 2240 EAAQSR----------RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2289
Query: 3241 SFRGLR-RQVSASELHTSGILGPETLRDLAQGTKTLQ----EVTEMDSVKRYL-EGTSCI 3294
LR +Q + +E+ +TLR AQ + L ++ E D K L E +
Sbjct: 2290 EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRL 2349
Query: 3295 AGVLVPAKDQPGRQEK--------MSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 3346
A Q + E+ M + + AL+L + F+ +
Sbjct: 2350 KAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEK 2409
Query: 3347 LRLSVEEAVAAGVVGGE----------------------IQEKLLSAERAVTGYTDPYTG 3384
++ EEA V E ++EK+ + + A +
Sbjct: 2410 MKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2469
Query: 3385 QQ---ISLFQA---------MQKDLIVREHGI-RLLEA----QIATGGVIDPVHSHRVPV 3427
QQ ++ QA M + L G R LEA Q+ + + +
Sbjct: 2470 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2529
Query: 3428 DVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLL--RRCVPDPDTGLYMLQL 3485
A R D + R A+ + + T E +T VQ L +R D D +
Sbjct: 2530 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI 2589
Query: 3486 AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRA 3545
A +L +E + L + Q Q + + L +SE + LL R R
Sbjct: 2590 AELEREKEKLQQEAK--LLQLKSEEMQTVQQEQLLQETQALQQSFLSE--KDSLLQRERF 2645
Query: 3546 GTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPV- 3604
+L +A+AQ Q R E + + + A+ME R V
Sbjct: 2646 IEQEKAKLEQLFQDEVAKAQ-QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2704
Query: 3605 --WDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRG 3662
+ L +EELLAE + L +L + E+ A ++ +
Sbjct: 2705 RKQEELQQLEQQRRQQEELLAE------ENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2758
Query: 3663 PREPGPAGRG--DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG 3720
+ P GR DG + ++ E +G ++ +A R QE + A E+QR QG
Sbjct: 2759 ATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ----RLQEAGILSAE-ELQR-LAQG 2812
Query: 3721 RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 3780
+ E R E + + G + L+ ++ T E+LS + L+
Sbjct: 2813 HTT----------VDELARREDVRHYLQGRSSIAGLL------LKATNEKLSV--YAALQ 2854
Query: 3781 RQVSA---------SELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 3831
RQ+ + ++ + +L P R L + V + + L + G
Sbjct: 2855 RQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGY 2914
Query: 3832 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 3891
P Q ++S++QAM KG++ + LLEAQ ATG VIDPV + R+ V+ A
Sbjct: 2915 KDPYTGQ-----QISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRR 2969
Query: 3892 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEA--QIATGG 3949
G E+ L G+ DP T + ++ Q +++ + E G+ LL + A GG
Sbjct: 2970 GYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGG 3029
Query: 3950 VI--------DPVHSHRVPVDVAYRRG------------YFDEEMNRVLADPSDDTKGFF 3989
+ D V +G YF E R L +
Sbjct: 3030 ELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITV 3089
Query: 3990 DPNTHENLTYVQL-----------LRRCVPDP--------DTGLYMLQLAGRGSAVHQLS 4030
+ +T V+ LR VP D LY QL +V ++
Sbjct: 3090 EKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQ-QLQRGERSVRDVA 3148
Query: 4031 E--ELRCALRDARVTPGSGALQ-GQSVSVWELLFYREVSEDRRQDLLSRYRASTLTVEEL 4087
E +R ALR A V G + GQ +S++ L ++DLL A L +
Sbjct: 3149 EVDTVRRALRGANVIAGVWLEEAGQKLSIYNAL---------KKDLLPSDMAVALLEAQA 3199
Query: 4088 GAT-LTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGR--LRGRAVPVWDVLAS 4144
G + A+ AG P+ E L +A V R G++V ++ L
Sbjct: 3200 GTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKK 3259
Query: 4145 GYVSRAAREELL-AEFGSGTLDLPALTRRLTAII--------EEAEEAPGARPQLQDAWR 4195
G + R LL A+ +G + P+ + R+ + EE A A A+
Sbjct: 3260 GLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYS 3319
Query: 4196 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ---------TLRDATME 4246
P PA G+ + R Q G + + AA RQE+ T +E
Sbjct: 3320 DPSTGEPATYGELQ--QRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVE 3377
Query: 4247 VQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEE-RL 4305
V G F+GR V+VW+++ S Y + +R ELL Q G + + ++ +L ++EE E R
Sbjct: 3378 VPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQ 3437
Query: 4306 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 4365
++SF GLR V ASEL SG+L L G T+++++E+ SV+ L+G+ C+AG+
Sbjct: 3438 ERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGI 3497
Query: 4366 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 4425
+ +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL V EAV A
Sbjct: 3498 YLE-----DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKA 3552
Query: 4426 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 4485
GVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATGG+I
Sbjct: 3553 GVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGII 3612
Query: 4486 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 4545
DPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+
Sbjct: 3613 DPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPE 3672
Query: 4546 TGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYRE 4598
TGL +L L G A EE R A + ++ PG G+ G ++S+WE++
Sbjct: 3673 TGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDL 3732
Query: 4599 VSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EA 4642
+ E++R L++ ++AG +T E + + ++ + + + R A EA
Sbjct: 3733 IPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEA 3792
Query: 4643 GSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYV 4681
+ LR T ++ G + G +P ++ L G +
Sbjct: 3793 RIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLL 3852
Query: 4682 SG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRG 4740
S AR L A+ +G L P RLT ++EA P+L D A G
Sbjct: 3853 SAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTG 3907
Query: 4741 DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSS 4800
D Q + +E A R + L + R F P+ V
Sbjct: 3908 YRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRG 3964
Query: 4801 YLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------- 4840
YL++ D+ L + V + V T+ERLS
Sbjct: 3965 YLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLP 4013
Query: 4841 -----KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSC 4895
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSC
Sbjct: 4014 LSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSC 4071
Query: 4896 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 4955
IAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEE
Sbjct: 4072 IAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 4126
Query: 4956 AVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 5015
AV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIAT
Sbjct: 4127 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4186
Query: 5016 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRAT 5075
GG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTYLQL++R
Sbjct: 4187 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4246
Query: 5076 LDPETGLLFLSL 5087
DP+TGL L L
Sbjct: 4247 TDPQTGLCLLPL 4258
Score = 619 bits (1597), Expect = e-176
Identities = 476/1531 (31%), Positives = 736/1531 (48%), Gaps = 227/1531 (14%)
Query: 40 ARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKAL 99
A IAGV++E +GQ S+Y A+++ LLP+ + ALLEAQA TG ++D A L V +A+
Sbjct: 3160 ANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEAV 3219
Query: 100 QQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGG 159
+ GLVG E EKLL+AE+A TGY DPY G+ ++LFQA+ K ++ R G L+ QL+TGG
Sbjct: 3220 RAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTGG 3279
Query: 160 LVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCV 219
+VDP++ V + AC +G LD ET LS P + +P+T E TY +L +RC
Sbjct: 3280 IVDPSKSHRVPLDVACARGCLDEETSRALS--APRADAKAYSDPSTGEPATYGELQQRCR 3337
Query: 220 RAPGSGLALLPL------------------KITFRS----------MGGAVSAAELLEVG 251
+GL+LLPL + TF G V+ EL+
Sbjct: 3338 PDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISSE 3397
Query: 252 ILD-EQAVQGLREGRLAAV--------------DVSARAEVRRYLEGTGS--------VA 288
EQ + LR+ R V +V + R G + +
Sbjct: 3398 YFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLAS 3457
Query: 289 GVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAG-- 346
GV+ + + + + L +G+ LL+ + T +++ + EA+R G
Sbjct: 3458 GVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGLL 3517
Query: 347 -----------------LVSPELHEQLLVAE-------------------QAVTGHHDPF 370
LV P +++L V E +AVTG+ DP+
Sbjct: 3518 RATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDPY 3577
Query: 371 SGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQR 430
SGS I LFQAM+KGLV R +RLL+AQ+ATGG++ P R+P++ A + G E+ R
Sbjct: 3578 SGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMNR 3637
Query: 431 QLSQ-----AGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPP-FIK 484
L+ G F TH L Y QLL CV DPETGL LPL G + + + +
Sbjct: 3638 VLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVETTQVYTE 3697
Query: 485 YSTRQALSTATATV-SVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAA 543
TR+A + G G +SLWE++ S+ I EQRA L +Q G ++ E++
Sbjct: 3698 EETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMII 3757
Query: 544 ELSATLEQAAATAR---VTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLA 600
+ +E+ + ++ +R +T +L +A II + Y L G + ++
Sbjct: 3758 IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAE 3817
Query: 601 SAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANK 660
SA YL GTG +AG+ LPGS++ LSIY+A KGLL A +LLEAQAATGF++DP +
Sbjct: 3818 SAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGE 3877
Query: 661 GHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLL 720
+V+EA+R ++GP++ +LLSAERAVTGY DPYT Q ISLFQAM+K LI E +RLL
Sbjct: 3878 RLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLL 3937
Query: 721 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQ 780
+AQ+ATGG++DP +P++VAY+RGY ++ + L +PS + + + DP+T E L+Y Q
Sbjct: 3938 DAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQ 3996
Query: 781 LLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSE 840
LL RC RD TG LLPLS A + F+ L ++++ EL+ S+
Sbjct: 3997 LLRRCRRDDGTGQLLLPLS--------DARKLTFRGL----------RKQITMEELVRSQ 4038
Query: 841 YFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQ 900
E QL E + K LE T A + + A + R++V+Q ++ GII
Sbjct: 4039 VMDEATALQLREGLTSIEEVTKNLQKFLEG-TSCIAGVFVDATKERLSVYQAMKKGIIRP 4097
Query: 901 QLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVA 960
++L A G V G +L++ +A+R ++GP
Sbjct: 4098 GTAFELLEAQ-------------------AATGYVIDPIKGLKLTVEEAVRMGIVGPEFK 4138
Query: 961 LALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQV 1020
LL A+ A DP+S + +S+ +A+++G++ + RL A+ A G DP ++
Sbjct: 4139 DKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRL 4198
Query: 1021 SVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSS 1080
V A K+GL E L + T G DP + +L
Sbjct: 4199 PVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENL---------------------- 4236
Query: 1081 SETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPT--EEQVQRSLQAVPGA 1138
+Y QL+E C D +GL LLPL E T + V++ +
Sbjct: 4237 -------------TYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDP 4283
Query: 1139 KDGTSLWDLLSSCHFTEEQRRGLLE-----DVQEGRTTVPQLLASVQRWVQETKLLAQAR 1193
+ G + E R+GL++ ++ E ++ S V ++ ++ +
Sbjct: 4284 ETGKEM-------SVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRR- 4335
Query: 1194 VMVPGPRGEVPAVWLLDAGIITQETLEALAQGTQSPAQVAE------------------- 1234
G + ++ + +I + L+ GT S + A+
Sbjct: 4336 ---SGRQYDIDDA--IAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSS 4390
Query: 1235 -----QPAV---KACLWG-----TGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLE 1281
PAV + W TG VAG+L + K SI +A+ L+ GQRLLE
Sbjct: 4391 SSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLE 4450
Query: 1282 AQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQA 1341
AQ +G ++DP +R V DAV GLV + + +++ A++A G+ DP ++ +S QA
Sbjct: 4451 AQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQA 4510
Query: 1342 MEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNK 1401
++KG + G L+VQ TGG+++P +P A + G +D +T+Q L V +K
Sbjct: 4511 LKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSK 4570
Query: 1402 FFFDPSARDQVTYQQLRERCVCDSETGLLLL 1432
+ P + +++Y+ +R + + TGL LL
Sbjct: 4571 YLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4601
Score = 350 bits (897), Expect = 3e-95
Identities = 288/927 (31%), Positives = 451/927 (48%), Gaps = 110/927 (11%)
Query: 4243 ATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE 4302
AT+ G+FQG+ V++W+++ S Y + +R +LL Q G + + ++ ++ V+EE E
Sbjct: 3045 ATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE 3104
Query: 4303 ERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCI 4362
++ ++ F GLR V A+EL S ++ E + L +G +++++V E+D+V+R L G + I
Sbjct: 3105 QK-GRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRALRGANVI 3163
Query: 4363 AGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEA 4422
AGV + Q K+SIY A+ K +L A+ LLEAQA TG +IDP + RL+V+EA
Sbjct: 3164 AGVWLEEAGQ-----KLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEA 3218
Query: 4423 VAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 4482
V AG+VG E EKLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++TG
Sbjct: 3219 VRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTG 3278
Query: 4483 GVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVP 4542
G++DP SHRVP+DVA RG DEE +R L+ P D K + DP+T E TY +L +RC P
Sbjct: 3279 GIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRCRP 3338
Query: 4543 DPDTGLYMLQLAGRGSAVHQLSEELRCALRDARV---TPGS---GALQGQSVSVWELLFY 4596
D TGL +L L+ + + Q EEL L+ TP G +G++V+VWEL+
Sbjct: 3339 DQLTGLSLLPLSEKAARARQ--EELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3396
Query: 4597 REVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAE-AGSPRPDPREAL-- 4653
+ ++RQ+LL ++R G +TVE++ L +++ + + + +G P P L
Sbjct: 3397 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3456
Query: 4654 -----RAATMEVKVGR---------------LRGRA-------------VPVWDVLASGY 4680
RA ++K G+ L+G V +++ + G
Sbjct: 3457 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3516
Query: 4681 VSGAAREELL-AEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGR 4739
+ LL A+ +G L P +RL + EA +A P+L + E G
Sbjct: 3517 LRATTAALLLEAQAATGFLVDPVRNQRL--YVHEAVKAGVVGPELHEQLLSA-EKAVTGY 3573
Query: 4740 GDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQF----QGRPVSVWD 4795
D SG + Q A ++ +R ++ G V V
Sbjct: 3574 RDPYSGSTISLFQ---------AMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3624
Query: 4796 VLFSSYLSEARRDELLAQHAAGALGLPD--------LVAVLTRVIEETEERLSKVSFRGL 4847
Y SE + +LA + G D +L R +E+ E L + +G
Sbjct: 3625 AYQRGYFSE-EMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGA 3683
Query: 4848 RRQ--VSASELHTSGILG---PETLRDLAQG------TKTLQEVTEMDSVK--------- 4887
+ V ++++T ET D+ G T +L EV + D +
Sbjct: 3684 EKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMA 3743
Query: 4888 -----RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFV 4942
R + I + + K + RQ+ ++ Y V R TA L EA+ +
Sbjct: 3744 DFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDY----VRRRLTAEDLFEARIISLET 3799
Query: 4943 IDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 5002
+ +R S+ EA+ A E L +V G P + Q +S++QA++K L+
Sbjct: 3800 YNLLREGTRSLREALEA-----ESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSA 3854
Query: 5003 EHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTH 5062
E LLEAQ ATG ++DPV R+ VD A R+G E++ L G+ DP T
Sbjct: 3855 EVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTE 3914
Query: 5063 ENLTYLQLLQRATLDPETGLLFLSLSL 5089
+ ++ Q +++ + E L L L
Sbjct: 3915 QTISLFQAMKKELIPTEEALRLLDAQL 3941
Score = 347 bits (889), Expect = 2e-94
Identities = 202/360 (56%), Positives = 242/360 (67%), Gaps = 25/360 (6%)
Query: 4746 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 4801
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2671 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2730
Query: 4802 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 4848
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2731 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2787
Query: 4849 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 4908
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2788 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2844
Query: 4909 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 4968
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2845 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2902
Query: 4969 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 5028
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2903 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2962
Query: 5029 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLS 5088
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLL+R DPETGL L L+
Sbjct: 2963 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 3022
Score = 254 bits (648), Expect = 2e-66
Identities = 137/307 (44%), Positives = 206/307 (67%), Gaps = 8/307 (2%)
Query: 4784 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE--ERLSK 4841
G G +S+W+V+ S + E +R +L+A AG + ++ ++ +IE+TE +
Sbjct: 3715 GSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGL 3774
Query: 4842 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 4901
S+ +RR+++A +L + I+ ET L +GT++L+E E +S YL GT +AGV +
Sbjct: 3775 ASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYL 3834
Query: 4902 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 4961
P G ++ +SIYQA+ KG+L A +LLEAQAATGF++DPV+ RL+V+EAV G+
Sbjct: 3835 P-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGL 3889
Query: 4962 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 5021
VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI E +RLL+AQ+ATGG++DP
Sbjct: 3890 VGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDP 3949
Query: 5022 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETG 5081
+P++VAY+RGY +++ + L++PS + + + DP+T E L+Y QLL+R D TG
Sbjct: 3950 RLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQLLRRCRRDDGTG 4008
Query: 5082 LLFLSLS 5088
L L LS
Sbjct: 4009 QLLLPLS 4015
Score = 107 bits (267), Expect = 3e-22
Identities = 73/212 (34%), Positives = 111/212 (52%), Gaps = 5/212 (2%)
Query: 4347 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4406
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4402 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4456
Query: 4407 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 4466
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4457 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4516
Query: 4467 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 4526
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4517 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4576
Query: 4527 THENLTYVQLLRRCVPDPDTGLYMLQLAGRGS 4558
T ++Y L R + + TGL +L+ A + +
Sbjct: 4577 TKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4608
Score = 107 bits (266), Expect = 4e-22
Identities = 73/210 (34%), Positives = 109/210 (51%), Gaps = 5/210 (2%)
Query: 4881 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4940
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4402 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4456
Query: 4941 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 5000
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4457 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4516
Query: 5001 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 5060
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4517 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4576
Query: 5061 THENLTYLQLLQRATLDPETGLLFLSLSLQ 5090
T ++Y L R+ ++ TGL L + Q
Sbjct: 4577 TKLKISYKDALDRSMVEEGTGLRLLEAAAQ 4606
Score = 105 bits (261), Expect = 2e-21
Identities = 69/217 (31%), Positives = 114/217 (52%), Gaps = 3/217 (1%)
Query: 13 GTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQ 72
G++S+ S P L + + P + +AG+ + + S+ AM + L+ GQ
Sbjct: 4388 GSSSSYPIS-PAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQ 4446
Query: 73 ALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLA 132
LLEAQA TGG++D + G+ PV+ A+ +GLV + +++ A++A G+ DP K++
Sbjct: 4447 RLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMS 4506
Query: 133 LFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLLDRETWHKLSELE 192
QA+ K + GQ +LEVQ TGGL++P V + A +G +D T KL ++
Sbjct: 4507 AAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV- 4565
Query: 193 PGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALL 229
G P T +++Y L+R + G+GL LL
Sbjct: 4566 -GAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4601
Score = 70.5 bits (171), Expect = 4e-11
Identities = 61/227 (26%), Positives = 102/227 (44%), Gaps = 17/227 (7%)
Query: 4832 IEETEERLS--KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 4889
++ T+ERLS + +G+ R +A EL + + + T++E M V
Sbjct: 4077 VDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPE 4136
Query: 4890 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 4949
+ A V P + +S++QAM KG++ + LLEAQ ATG +IDP +
Sbjct: 4137 FKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESH 4196
Query: 4950 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 5009
RL VE A G+ E+ E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4197 RLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLL 4256
Query: 5010 -------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 5041
E + ++ ++DP + V AYR+G D +
Sbjct: 4257 PLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4303
Score = 60.8 bits (146), Expect = 3e-08
Identities = 32/119 (26%), Positives = 61/119 (51%)
Query: 4971 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 5030
L ++ G T +++S++ A+Q+ L+ + LLEAQ A+G ++DPV + R+ V+
Sbjct: 2829 LQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVN 2888
Query: 5031 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSL 5089
A + G E++ L G+ DP T + ++ Q +Q+ + E G+ L +
Sbjct: 2889 EAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQI 2947
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4254 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4310
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4337 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4392
Query: 4311 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4359
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4393 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4452
Query: 4360 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4386
+C G++ P+ + P + KMS QA+
Sbjct: 4453 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4512
Query: 4387 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4446
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4513 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4572
Query: 4447 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 4487
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4573 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4614
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4788 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4844
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4337 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4392
Query: 4845 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4893
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4393 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4452
Query: 4894 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4920
+C G++ P+ + P + KMS QA+
Sbjct: 4453 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4512
Query: 4921 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4980
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4513 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4572
Query: 4981 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 5021
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4573 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4614
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 1268 bits (3280), Expect = 0.0
Identities = 798/1967 (40%), Positives = 1134/1967 (57%), Gaps = 218/1967 (11%)
Query: 1511 AAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLEGG 1570
AAE +P + +F GLR++VSA+ L A ++S + L L+QG TTV E+A + V+ L+G
Sbjct: 2615 AAEAEP-EHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGR 2673
Query: 1571 NFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFK 1630
+ IAG+L++ T E++S+ AL+R +L PGTAL+LLEAQAA+GF++DP NR+LTV EA K
Sbjct: 2674 SSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVK 2733
Query: 1631 AGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGI 1690
G+ G E + KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGG+
Sbjct: 2734 EGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGV 2793
Query: 1691 IDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 1750
IDPVHSHRVPVDVAYR GYFDEEMNR+LADPSDDTKGFFDPNTHENLTYLQLLERCVEDP
Sbjct: 2794 IDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 2853
Query: 1751 ETGLYLLQI---IKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTE 1807
ETGL LL + KG VY + R V + T G+F + V+ W++++S YFT
Sbjct: 2854 ETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTA 2913
Query: 1808 DRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLFNSRVIDQ 1867
+++R+L++++ +EK+++II T +EE E Q + +R V AA+L SRVID+
Sbjct: 2914 EQRRDLLRQFRTGRITVEKIIKIIITVVEEQE-QKGRLCFEGLRSLVPAAELLESRVIDR 2972
Query: 1868 KTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFA 1927
+ L+ G + ++ ++ V+ L G++ IAGV + + +S++ A +K+L+P+ A
Sbjct: 2973 ELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMA 3032
Query: 1928 TWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTI 1987
LLEAQA TG ++DP T +L+VDEAV GLV E E+LL AE+A TGYRDP TG ++
Sbjct: 3033 VALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSV 3092
Query: 1988 PLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQ 2047
LFQA++K LI + + LRLL+ Q++TGG++DP HR+PL+ A RGCL ++ +S
Sbjct: 3093 SLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAP 3152
Query: 2048 KHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVN-KAAR---DSEHIDDETRRAL 2103
+ K + DP+T E +Y ELQ+RCRP + TG L P++ KAAR + + + + R
Sbjct: 3153 RADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETF 3212
Query: 2104 EAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIE 2163
E VE+ VG F+G+ T+W L++SEY T E++ +L+R +RT + ++ V ++++ ++E
Sbjct: 3213 EKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRT-GKVTVEKVIKILITIVE 3271
Query: 2164 KQET-SNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEG 2222
+ ET + L F G+R + ASELL+S +++ + L+ G++T ++L E V+ L+G
Sbjct: 3272 EVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQG 3331
Query: 2223 TSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLS 2282
+ C+AG+ + +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL
Sbjct: 3332 SGCLAGIYL-----EDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLY 3386
Query: 2283 VEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQ 2342
V E V AGVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQ
Sbjct: 3387 VHEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQ 3446
Query: 2343 IATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLR 2402
IATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL
Sbjct: 3447 IATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLE 3506
Query: 2403 RCVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVW 2455
RCV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+W
Sbjct: 3507 RCVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLW 3566
Query: 2456 ELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAE 2503
E++ + E++R L++ ++AG +T E + + ++ + + + R
Sbjct: 3567 EVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLT 3626
Query: 2504 A----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWD 2538
A EA + LR T ++ G + G +P ++
Sbjct: 3627 AEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQ 3686
Query: 2539 VLASGYVS-RAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDARRGPRE 2597
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3687 ALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER 3744
Query: 2598 PGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSV 2657
A G D Q + +E A R + L + R F P+ V
Sbjct: 3745 ---AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV 3800
Query: 2658 WDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS------------- 2704
YL++ D+ L + V + V T+ERLS
Sbjct: 3801 --AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDG 3847
Query: 2705 ------------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKR 2752
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ ++++
Sbjct: 3848 TGQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQK 3905
Query: 2753 YLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 2812
+LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++
Sbjct: 3906 FLEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKG 3960
Query: 2813 LRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRL 2872
L+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRL
Sbjct: 3961 LKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRL 4020
Query: 2873 LEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYV 2932
LEAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+
Sbjct: 4021 LEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYL 4080
Query: 2933 QLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELL 2992
QL+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4081 QLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE-- 4134
Query: 2993 FYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALR 3052
YR G + + T L Q E S
Sbjct: 4135 ---------------AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------D 4165
Query: 3053 AATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEA 3112
+ + R GR + D +A + +A L ++ +GTL + L+
Sbjct: 4166 GVVKSMIIDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS------ 4215
Query: 3113 EEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTL 3172
G++G + G + + A +R Q +
Sbjct: 4216 ---------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASW 4248
Query: 3173 RDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVA 3224
D T E G G VS+ + + + + LL AQ G +
Sbjct: 4249 SDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI------- 4299
Query: 3225 VLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQE 3277
+ T ER ++ +GL ++ ++ + G P T ++ +
Sbjct: 4300 ----IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKG 4355
Query: 3278 VTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 3337
++ +R+LE G++ P D PGR + + +A+ +G + TA L + A +
Sbjct: 4356 WLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYS 4410
Query: 3338 GFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3383
++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4411 KYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4457
Score = 1127 bits (2914), Expect = 0.0
Identities = 724/1911 (37%), Positives = 1065/1911 (55%), Gaps = 110/1911 (5%)
Query: 522 EQRAMLAQQYQEGTLSVEKL-AAELSAT---------LEQAAATARV--TFSGLRDTVTP 569
EQ +L +Q++ E++ A++++AT L+ AA A +F GLR V+
Sbjct: 2574 EQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSA 2633
Query: 570 GELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEA 629
L +A I+ + +RL G T ++ + YLQG IAGLLL + E+LS+Y A
Sbjct: 2634 QRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAA 2693
Query: 630 RCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVT 689
+ LL PGTALILLEAQAA+GF++DP N+ +V EA++ V+GP++ KLLSAERAVT
Sbjct: 2694 LQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVT 2753
Query: 690 GYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 749
GY DPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF
Sbjct: 2754 GYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 2813
Query: 750 DQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSP----- 804
D+ +N +L DPSDDTKGFFDPNTHENLTYLQLLERCV DPETGL LLPL+ +
Sbjct: 2814 DEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELV 2873
Query: 805 LVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQV 864
DS + F+ +S +G+FQG+ V+ WE+INSEYF+ +RR LLR++R +T+ ++
Sbjct: 2874 YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKI 2933
Query: 865 AKLLEA---ETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDG 921
K++ E +++ + LRS V +LLE+ +ID++L Q+ G S + +D
Sbjct: 2934 IKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDT 2993
Query: 922 VRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPES 981
VRR L G + GV L +GQ+LS+Y A+++ LL +A+ALLEAQA TG I+DP +
Sbjct: 2994 VRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSAR 3053
Query: 982 LSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLE 1041
L+VDEAVR G+VGPE + +L AE A+ G+RDP++G+ VS+FQA+KKGLIP EQ RLL+
Sbjct: 3054 LTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLD 3113
Query: 1042 AQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSS---SSETFPTPDGQGRTSYAQL 1098
AQ++TGGI+DP+ H +P+ VA RG +D+E ALS+ ++ + P +Y +L
Sbjct: 3114 AQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGEL 3173
Query: 1099 LEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQA------------VPGAKDGT-SLW 1145
+ C D+ +GL LLPL E A A +E++ LQA V G K T ++W
Sbjct: 3174 QQRCRPDQLTGLSLLPLSEKA-ARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVW 3232
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+SS +FT EQR+ LL + G+ TV +++ + V+E + L Q R+ G R VPA
Sbjct: 3233 ELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPA 3292
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQA 1265
LL +G++++ E L G + ++E +V+ L G+GC+AG+ L+ + K SI +A
Sbjct: 3293 SELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEA 3352
Query: 1266 VRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAA 1325
+R GLL LLEAQ A+GFLVDP+ NQRL V +AVK G+VG EL EQL AE+A
Sbjct: 3353 MRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVT 3412
Query: 1326 GYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLL 1385
GY DPYS +++SL+QAM+KGLV + G+ LL+ Q+ATGG++DPVH +P A + G
Sbjct: 3413 GYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYF 3472
Query: 1386 DTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDH 1445
+ ++VL D K FFDP+ + +TY+QL ERCV D ETGL LLPL EV +
Sbjct: 3473 SEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVET 3532
Query: 1446 TAV--------ALRAMKVPV-STGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAA 1496
T V A ++ + G G ++SLW+++ S+ + ++R +L+A ++GR
Sbjct: 3533 TQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVT 3592
Query: 1497 ALRQVVSAVTALVEAAE--RQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTV 1554
R ++ + ++E E RQ A++ +R++++A DLF A++IS +T + L +GT ++
Sbjct: 3593 KERMII-IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSL 3651
Query: 1555 KEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFI 1614
+E E +S L G +AGV + G+++ +SI +AL++ +L A +LLEAQAATGF+
Sbjct: 3652 REALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFL 3711
Query: 1615 IDPAENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 1674
+DP + +LTV+EA + G+ G E + +LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3712 LDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPT 3771
Query: 1675 EHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTH 1734
E +RLL+AQ+ATGGI+DP +P++VAY+ GY +++ + L++PS+ + + DP+T
Sbjct: 3772 EEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSE-VRSYVDPSTD 3830
Query: 1735 ENLTYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVV 1794
E L+Y QLL RC D TG LL + A+ R + +
Sbjct: 3831 ERLSYTQLLRRCRRDDGTGQLLLPL--------------------SDARKLTFRGLRKQI 3870
Query: 1795 SFWDLLSSPYFTED---RKRELIQEYGAQSGGLEKLLE-------IITTTIEETETQNQG 1844
+ +L+ S E + RE + + L+K LE + +E + Q
Sbjct: 3871 TMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQA 3930
Query: 1845 IKVAAIRG----EVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIA 1900
+K IR E+ A VID L V + E L +
Sbjct: 3931 MKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVT 3990
Query: 1901 GVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLV 1960
G P + +++SL +A +K LI LLEAQ ATG ++DP +L V+ A GL
Sbjct: 3991 GYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLF 4050
Query: 1961 NEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLL------------- 2007
+EE+ E L G+ DP T + + Q M++ + + L LL
Sbjct: 4051 DEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSS 4110
Query: 2008 --EVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSY 2065
V+ ++DP+ + + AYR+G + Y +S+Q+ + ++ V
Sbjct: 4111 KSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKS 4170
Query: 2066 RELQERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALE----AEQVEITVGRFRGQKPT 2121
+ R Q D + + K D +D L A+ + G FR + +
Sbjct: 4171 MIIDRRSGRQYD---IDDAIAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSS 4227
Query: 2122 LWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQI 2181
+ + + + QL + T L E +EK S + + I
Sbjct: 4228 VGSSSSYPISPAVSRTQLA-SWSDPTEETGPVAGILDTETLEK--VSITEAMHRNLVDNI 4284
Query: 2182 TASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQE 2241
T LL + T ++ R + + V + + +A + P +
Sbjct: 4285 TGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKT 4344
Query: 2242 KMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLL 2301
KMS QA+ KG L LE Q TG +I+P R+ ++E + G V + +KL
Sbjct: 4345 KMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLR 4404
Query: 2302 SAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 2351
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4405 DVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4455
Score = 1054 bits (2725), Expect = 0.0
Identities = 630/1557 (40%), Positives = 924/1557 (59%), Gaps = 83/1557 (5%)
Query: 869 EAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCG 928
EAE + D LR +V+ +L EAGI+ + L ++ G + + L + VR YL G
Sbjct: 2617 EAEPEHSFD----GLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQG 2672
Query: 929 LGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAV 988
++ G+ L + ++LS+Y A++++LL P AL LLEAQAA+G ++DP L+V+EAV
Sbjct: 2673 RSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAV 2732
Query: 989 RRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGG 1048
+ GVVGPEL+ +L AE A+ G++DP++G+Q+S+FQAM+KGLI E RLLEAQ+ATGG
Sbjct: 2733 KEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGG 2792
Query: 1049 IIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRD 1105
+IDP H +P+ VA +RGY D+EM L+ S+ F P+ +Y QLLE C D
Sbjct: 2793 VIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVED 2852
Query: 1106 ETSGLHLLPLPESAPA--------LPTEEQVQRSLQAVPGAK---DGTSLWDLLSSCHFT 1154
+GL LLPL + A + +++ + P K ++W++++S +FT
Sbjct: 2853 PETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFT 2912
Query: 1155 EEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDAGII 1214
EQRR LL + GR TV +++ + V+E + + R+ G R VPA LL++ +I
Sbjct: 2913 AEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE--QKGRLCFEGLRSLVPAAELLESRVI 2970
Query: 1215 TQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTG 1274
+E + L +G +S VAE V+ L G +AGV L+ +G K SI A++ LLP+
Sbjct: 2971 DRELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSD 3030
Query: 1275 LGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRA 1334
+ LLEAQ +G ++DP + RL+V++AV+ GLVG E E+L AE+A GY DPY+
Sbjct: 3031 MAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQ 3090
Query: 1335 SLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLT 1394
S+SL+QA++KGL+P+ +GL LL QL+TGG+VDP +P AC G LD +TS+ L+
Sbjct: 3091 SVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALS 3150
Query: 1395 AVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMK 1454
A D K + DPS + TY +L++RC D TGL LLPL + L+A +
Sbjct: 3151 APRADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARE 3210
Query: 1455 ------VPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVTAL 1508
V V G FKG +V++W+L+ SEY A++R+EL+ R+G+ + + +T +
Sbjct: 3211 TFEKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIV 3270
Query: 1509 VEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
E + + +F GLR V A +L + ++SR ++L G TTVK+++E+ SV+ L+
Sbjct: 3271 EEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQ 3330
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G +AG+ ++ T+E++SI EA+RR +LR TA +LLEAQAATGF++DP N++L V EA
Sbjct: 3331 GSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEA 3390
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 1688
KAG+ G E + +LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATG
Sbjct: 3391 VKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATG 3450
Query: 1689 GIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVE 1748
GIIDPVHSHRVPVDVAY+ GYF EEMNR+LADPSDDTKGFFDPNTHENLTY QLLERCVE
Sbjct: 3451 GIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVE 3510
Query: 1749 DPETGLYLLQI--IKKGE----NYVYINEATRHVLQSRTAKM-RVGRFADQVVSFWDLLS 1801
DPETGL LL + +K E VY E TR + + G +S W+++
Sbjct: 3511 DPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQ 3570
Query: 1802 SPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETE-TQNQGI-KVAAIRGEVTAADL 1859
S E+++ +L+ ++ A E+++ II IE+TE + QG+ +R +TA DL
Sbjct: 3571 SDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDL 3630
Query: 1860 FNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRK 1919
F +R+I +T + LR G + E YL G+ +AGV +P +R+ +S+++A +K
Sbjct: 3631 FEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKK 3690
Query: 1920 ELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYR 1979
L+ A A LLEAQAATGFLLDP ++L+VDEAV GLV EL +RLL AERA TGYR
Sbjct: 3691 GLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYR 3750
Query: 1980 DPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKD 2039
DP T TI LFQAM+K+LI EALRLL+ Q+ATGG++DP+ LPLE AY+RG L+KD
Sbjct: 3751 DPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKD 3810
Query: 2040 IYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDET 2099
+ +S+ +R +VDP+T E++SY +L RCR + TG +L P++ A + +
Sbjct: 3811 THDQLSEPSEVRS-YVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT------- 3862
Query: 2100 RRALEAEQVEITVGRFRG--QKPTLWALLNSEYVTEEKKLQL------VRMYRTHTRRAL 2151
FRG ++ T+ L+ S+ + E LQL + + ++ L
Sbjct: 3863 ---------------FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFL 3907
Query: 2152 QTVAQLILELIE--KQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQE 2209
+ + + ++ K+ S +GI R TA ELL + T ++ ++ + T +E
Sbjct: 3908 EGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 3967
Query: 2210 LMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 2269
+ V + A V P + +S++QAM KG++ + LLEAQ AT
Sbjct: 3968 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4027
Query: 2270 GFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDL 2329
G +IDP + RL VE G+ E+ E L G+ DP T + ++ Q M++ +
Sbjct: 4028 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4087
Query: 2330 IVREHGIRLL-------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 2371
+ G+ LL E + ++ ++DP + V AYR+G D +
Sbjct: 4088 TDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4144
Score = 999 bits (2583), Expect = 0.0
Identities = 666/1843 (36%), Positives = 989/1843 (53%), Gaps = 126/1843 (6%)
Query: 234 TFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLL 293
+F + VSA L E GIL + +Q L +G +++ R +VR YL+G S+AG++L
Sbjct: 2623 SFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLK 2682
Query: 294 PEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELH 353
K S + A LL GTAL LLEAQAA+ L+DP+ +RL V+EAV+ G+V PELH
Sbjct: 2683 ATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELH 2742
Query: 354 EQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRL 413
+LL AE+AVTG+ DP++G QI LFQAM+KGL+ R +RLL+AQ+ATGG++ P R+
Sbjct: 2743 HKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRV 2802
Query: 414 PLEAALRCGCLDEDTQRQLSQA-----GSFSDGTHGGLRYEQLLALCVTDPETGLAFLPL 468
P++ A R G DE+ R L+ G F TH L Y QLL CV DPETGL LPL
Sbjct: 2803 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPL 2862
Query: 469 SG-GPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAML 527
+ +GGE + R AT + GKF+G+ V++WE++ SE ++EQR L
Sbjct: 2863 TDKAAKGGELV---YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDL 2919
Query: 528 AQQYQEGTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLE 587
+Q++ G ++VEK+ + +E+ R+ F GLR V ELL++ +ID++LY++L+
Sbjct: 2920 LRQFRTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQ 2979
Query: 588 HGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQ 647
G+ + +DV + + +R L+G IAG+ L + ++LSIY A K LL A+ LLEAQ
Sbjct: 2980 RGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQ 3039
Query: 648 AATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQ 707
A TG IIDP + +V+EA+RA ++GP+ KLLSAE+AVTGY DPYTGQ +SLFQA++
Sbjct: 3040 AGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALK 3099
Query: 708 KGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGF 767
KGLI RE G+RLL+AQ++TGG++DP SHRVP+DVA RG D+ + L P D K +
Sbjct: 3100 KGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAY 3159
Query: 768 FDPNTHENLTYLQLLERCVRDPETGLYLLPLS-----STQSPLV-DSATQQAFQNLLLSV 821
DP+T E TY +L +RC D TGL LLPLS + Q L + ++ F+ + V
Sbjct: 3160 SDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEV 3219
Query: 822 KYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQVAKLL-----EAETQRQA 876
G F+G+ V+ WELI+SEYF+ +R++LLR++R +VT+ +V K+L E ET RQ
Sbjct: 3220 PVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQE 3279
Query: 877 DIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVR 936
+ LR+ V +LL +G++ + +Q+ G + + L + VR L G G + G+
Sbjct: 3280 RLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIY 3339
Query: 937 LLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPE 996
L + +++S+Y+AMR+ LL A LLEAQAATG ++DP + L V EAV+ GVVGPE
Sbjct: 3340 LEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPE 3399
Query: 997 LYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHH 1056
L+ +L AE A+ G+RDP+SG +S+FQAM+KGL+ + RLLEAQ+ATGGIIDP H
Sbjct: 3400 LHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSH 3459
Query: 1057 HLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRDETSGLHLL 1113
+P+ VA QRGY +EM L+ S+ F P+ +Y QLLE C D +GL LL
Sbjct: 3460 RVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLL 3519
Query: 1114 PLPESAPA-------LPTEEQVQRSLQA----VPG----AKDGTSLWDLLSSCHFTEEQR 1158
PL + A + TEE+ +R+ + +PG SLW+++ S EEQR
Sbjct: 3520 PLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQR 3579
Query: 1159 RGLLEDVQEGRTTVPQLLASVQRWVQETKLL-AQARVMVPGPRGEVPAVWLLDAGIITQE 1217
L+ D Q GR T +++ + +++T+++ Q R + A L +A II+ E
Sbjct: 3580 AQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLE 3639
Query: 1218 TLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQ 1277
T L +GT+S + E + L+GTG VAGV L S SI QA++ GLL + +
Sbjct: 3640 TYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVAR 3699
Query: 1278 RLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLS 1337
LLEAQ A+GFL+DP+ +RL+V++AV+ GLVG EL ++L AERA GY DPY+ ++S
Sbjct: 3700 LLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTIS 3759
Query: 1338 LWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVD 1397
L+QAM+K L+P E L LL QLATGG+VDP G HLP A + G L+ T L+
Sbjct: 3760 LFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSE-P 3818
Query: 1398 KDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPV 1457
+ + + DPS ++++Y QL RC D TG LLLPL D + R ++ +
Sbjct: 3819 SEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPL--------SDARKLTFRGLRKQI 3870
Query: 1458 STGRFKGCSVSLWDLLLSEYVGADKRRELVALCR-SGRAAALRQVVSAVTALVEAAERQP 1516
+ V + E R L ++ + + S + + A ++
Sbjct: 3871 TMEELVRSQV------MDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKER 3924
Query: 1517 L---QATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSV-----KRSLE 1568
L QA +G+ + +A +L AQ + +D + TV+E M V + L
Sbjct: 3925 LSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLS 3984
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
+ G + + +S+ +A+++ ++ + LLEAQ ATG IIDP E+ +L VE A
Sbjct: 3985 AERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVA 4044
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL------- 1681
+K G+F +E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4045 YKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKR 4104
Query: 1682 EAQIATGG--------IIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNT 1733
E + ++ I+DP + V AYR G D +
Sbjct: 4105 ERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ-------------------- 4144
Query: 1734 HENLTYLQLLERCVEDPE------TGLYLLQIIKKGENYVY-INEATRHVLQSRTAKMRV 1786
TYL+L E+ E E G+ II + Y I++A L R+A +
Sbjct: 4145 ----TYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRSALDQY 4200
Query: 1787 GRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIK 1846
+ F D+LS R G+ S T ++ +
Sbjct: 4201 RAGTLSITEFADMLSG---NAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGP 4257
Query: 1847 VAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPS 1906
VA I T +V + +H V GQ L LE C G+ PS
Sbjct: 4258 VAGILDTETL-----EKVSITEAMHRNLVDNITGQRL---------LEAQACTGGIIDPS 4303
Query: 1907 TREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRE 1966
T E + +A K L+ + AQ A DP T+ K+S +A+ G + E +
Sbjct: 4304 TGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQ 4363
Query: 1967 RLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEV 2009
R L+ + G +P T +PL +A+Q+ ++ A +L +V
Sbjct: 4364 RFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV 4406
Score = 970 bits (2508), Expect = 0.0
Identities = 547/1287 (42%), Positives = 810/1287 (62%), Gaps = 33/1287 (2%)
Query: 1155 EEQRRGLL---EDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDA 1211
EEQ R L E+V + + L + + + A+ G R +V A L +A
Sbjct: 2580 EEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEA 2639
Query: 1212 GIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLL 1271
GI++ E L+ LAQG + ++A + V+ L G +AG+LL+ + K S+ A++ LL
Sbjct: 2640 GILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLL 2699
Query: 1272 PTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPY 1331
G LLEAQ ASGFL+DP+ N+RL+V +AVK G+VG EL +L AERA GY DPY
Sbjct: 2700 SPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPY 2759
Query: 1332 SRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQ 1391
+ +SL+QAM+KGL+ + G+ LL+ Q+ATGGV+DPVH +P A R G D + ++
Sbjct: 2760 TGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNR 2819
Query: 1392 VLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDT-----VLEVDDHT 1446
VL D K FFDP+ + +TY QL ERCV D ETGL LLPL ++ D
Sbjct: 2820 VLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEA 2879
Query: 1447 AVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVT 1506
V G+F+G +V++W+++ SEY A++RR+L+ R+GR + +++ +
Sbjct: 2880 RDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRIT-VEKIIKIII 2938
Query: 1507 ALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRS 1566
+VE E++ + F GLR V A +L +++I R+ +L +G +V++VAE+D+V+R+
Sbjct: 2939 TVVEEQEQKG-RLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 2997
Query: 1567 LEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVE 1626
L G N IAGV ++ +++SI AL++ +L A+ LLEAQA TG IIDPA + +LTV+
Sbjct: 2998 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVD 3057
Query: 1627 EAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIA 1686
EA +AG+ G E + KLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++
Sbjct: 3058 EAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLS 3117
Query: 1687 TGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERC 1746
TGGI+DP SHRVP+DVA G DEE +R L+ P D K + DP+T E TY +L +RC
Sbjct: 3118 TGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRC 3177
Query: 1747 VEDPETGLYLLQIIKKG----ENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSS 1802
D TGL LL + +K + +Y R + ++ VG F + V+ W+L+SS
Sbjct: 3178 RPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3237
Query: 1803 PYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQG-IKVAAIRGEVTAADLFN 1861
YFT ++++EL++++ +EK+++I+ T +EE ET Q + + +R V A++L
Sbjct: 3238 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3297
Query: 1862 SRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKEL 1921
S V+ + L+ G+T + LS L V+ L+GS C+AG+ + T+E +S++EA R+ L
Sbjct: 3298 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3357
Query: 1922 IPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDP 1981
+ A A LLEAQAATGFL+DP Q+L V EAV G+V EL E+LL AE+A TGYRDP
Sbjct: 3358 LRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDP 3417
Query: 1982 ATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIY 2041
+G TI LFQAMQK L+ + +RLLE Q+ATGG+IDP H HR+P++ AY+RG +++
Sbjct: 3418 YSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMN 3477
Query: 2042 ALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSE-------H 2094
+++D K F DPNT E ++YR+L ERC +TG L P+ K A +E +
Sbjct: 3478 RVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL-KGAEKAEVVETTQVY 3536
Query: 2095 IDDETRRALEAEQVEITVGRFRGQKP-TLWALLNSEYVTEEKKLQLVRMYRTHTRRALQT 2153
++ETRRA E Q++I G G +LW ++ S+ + EE++ QL+ ++ R +
Sbjct: 3537 TEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAG-RVTKER 3595
Query: 2154 VAQLILELIEKQETSNKH--LWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELM 2211
+ +I+E+IEK E + + +RR++TA +L + II+ E L G + +E +
Sbjct: 3596 MIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREAL 3655
Query: 2212 EDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGF 2271
E + YL GT +AGV +P G ++ +SIYQA+ KG+L A +LLEAQAATGF
Sbjct: 3656 EAESAWCYLYGTGSVAGVYLP-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGF 3710
Query: 2272 VIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIV 2331
++DPV+ RL+V+E V G+VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3711 LLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIP 3770
Query: 2332 REHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNT 2391
E +RLL+AQ+ATGG++DP +P++VAY+RGY +++ + L++PS + + + DP+T
Sbjct: 3771 TEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPST 3829
Query: 2392 HENLTYVQLLRRCVPDPDTGLYMLQLA 2418
E L+Y QLLRRC D TG +L L+
Sbjct: 3830 DERLSYTQLLRRCRRDDGTGQLLLPLS 3856
Score = 881 bits (2277), Expect = 0.0
Identities = 629/1746 (36%), Positives = 913/1746 (52%), Gaps = 133/1746 (7%)
Query: 41 RSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQ 100
R++ G +GQ S++ AM++GL+ G LLEAQ ATGG++D +PV A +
Sbjct: 2750 RAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR 2809
Query: 101 QGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEV--QLATG 158
+G E+ L T G+ DP E L Q + + V D G L + + A G
Sbjct: 2810 RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKG 2869
Query: 159 GLV----DPAQGVLVAPEPACHQGLLDRET---WHKLSELEPGTGDLR--FLNPNTLERL 209
G + A+ V + G +T W ++ E T + R L R+
Sbjct: 2870 GELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINS-EYFTAEQRRDLLRQFRTGRI 2928
Query: 210 TYHQLLERCVRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAV 269
T ++++ + ++ F + V AAELLE ++D + Q L+ G +
Sbjct: 2929 TVEKIIKIIITVVEEQEQ--KGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVR 2986
Query: 270 DVSARAEVRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLV 329
DV+ VRR L G +AGV L G K S + A + LLP A+ LLEAQA T ++
Sbjct: 2987 DVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHII 3046
Query: 330 DPITGQRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRP 389
DP T RL VDEAVRAGLV PE HE+LL AE+AVTG+ DP++G + LFQA+KKGL+ R
Sbjct: 3047 DPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPRE 3106
Query: 390 LALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLS----QAGSFSDGTHGG 445
LRLLDAQL+TGG+V P++ R+PL+ A GCLDE+T R LS A ++SD + G
Sbjct: 3107 QGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGE 3166
Query: 446 -LRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFR 504
Y +L C D TGL+ LPLS Q + + R+ V VG F+
Sbjct: 3167 PATYGELQQRCRPDQLTGLSLLPLSEKAARAR-QEELYSELQARETFEKTPVEVPVGGFK 3225
Query: 505 GRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAELSATLEQAAATA--RVTFSG 562
GR V++WEL+ SE ++EQR L +Q++ G ++VEK+ L +E+ R++FSG
Sbjct: 3226 GRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSG 3285
Query: 563 LRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQE 622
LR V ELL + ++ + +E+L+ G+ T KD+ L S + LQG+GC+AG+ L ++E
Sbjct: 3286 LRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKE 3345
Query: 623 RLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLL 682
++SIYEA +GLLR TA +LLEAQAATGF++DP N+ V EA++A V+GP++ +LL
Sbjct: 3346 KVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLL 3405
Query: 683 SAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDV 742
SAE+AVTGY DPY+G ISLFQAMQKGL++R+HGIRLLEAQIATGG+IDPVHSHRVPVDV
Sbjct: 3406 SAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3465
Query: 743 AYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQ 802
AY+RGYF + +N +L DPSDDTKGFFDPNTHENLTY QLLERCV DPETGL LLPL +
Sbjct: 3466 AYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAE 3525
Query: 803 SPLV--------DSATQQAFQNLLLSVK-YGRFQGQRVSAWELINSEYFSEGRRRQLLRR 853
V + T++AF+ + + G G +S WE++ S+ E +R QL+
Sbjct: 3526 KAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMAD 3585
Query: 854 YRQREVTLGQVAKLL-----EAETQRQADI-MLPALRSRVTVHQLLEAGIIDQQLLDQVL 907
++ VT ++ ++ + E RQ + +R R+T L EA II + + +
Sbjct: 3586 FQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLR 3645
Query: 908 AGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQ 967
GT S L + YL G G+V GV L S Q LS+YQA+++ LL VA LLEAQ
Sbjct: 3646 EGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQ 3705
Query: 968 AATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMK 1027
AATG ++DP E L+VDEAVR+G+VGPEL+ RL AE A+ G+RDP++ + +S+FQAMK
Sbjct: 3706 AATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMK 3765
Query: 1028 KGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSE--TFP 1085
K LIP E+A RLL+AQ+ATGGI+DP HLP+ VA QRGY++++ LS SE ++
Sbjct: 3766 KELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYV 3825
Query: 1086 TPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGTSLW 1145
P R SY QLL C RD+ +G LLPL ++ R L G + ++
Sbjct: 3826 DPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDA-----------RKL-TFRGLRKQITME 3873
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+ S E L +EG T++ ++ ++Q++++ T + A V V + +
Sbjct: 3874 ELVRSQVMDEATALQL----REGLTSIEEVTKNLQKFLEGTSCI--AGVFVDATKERLSV 3927
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAE---------QPAVKACLWG----------TG 1246
+ GII T L + + V + + AV+ + G
Sbjct: 3928 YQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAER 3987
Query: 1247 CVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKV 1306
V G SG S+ QA++ GL+ G RLLEAQ+A+G ++DP + RL VE A K
Sbjct: 3988 AVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKR 4047
Query: 1307 GLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLL---------- 1356
GL E++E L G+ DP + +L+ Q ME+ + GL LL
Sbjct: 4048 GLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERK 4107
Query: 1357 -----QVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQ 1411
V+ +VDP G + A R GL+D QT L+ + + ++
Sbjct: 4108 TSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECE---------WEE 4158
Query: 1412 VTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLW- 1470
+T D +++ S ++DD A L + +++ ++S+
Sbjct: 4159 ITISS------SDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRS---ALDQYRAGTLSITE 4209
Query: 1471 --DLLLSEYVGADKRRELVALCRS---GRAAALRQVVS---------AVTALVEAAERQP 1516
D+L G R V S A + Q+ S V +++ +
Sbjct: 4210 FADMLSGNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEK 4269
Query: 1517 L---QATFRGLRKQVSARDLFRAQ-----LISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
+ +A R L ++ + L AQ +I T + K + + V R
Sbjct: 4270 VSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINL 4329
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G T+ +MS +AL++ L LE Q TG +I+P ++ ++EA
Sbjct: 4330 AQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEA 4389
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-AT 1687
+ G T KL T P T +IS A+ + ++ G+RLLEA +T
Sbjct: 4390 LQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4449
Query: 1688 GGIIDP 1693
G P
Sbjct: 4450 KGYYSP 4455
Score = 869 bits (2246), Expect = 0.0
Identities = 711/2089 (34%), Positives = 1014/2089 (48%), Gaps = 390/2089 (18%)
Query: 2610 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 2665
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2512 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2571
Query: 2666 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 2712
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2572 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2628
Query: 2713 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 2772
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2629 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2685
Query: 2773 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 2832
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2686 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2743
Query: 2833 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2892
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2744 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2803
Query: 2893 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL- 2951
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L
Sbjct: 2804 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2863
Query: 2952 --AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRY 3009
A +G + E R A V+ G QG++V++WE++ + ++R+DLL ++
Sbjct: 2864 DKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQF 2923
Query: 3010 RAGTLTVEELGATLTSLLAQAQAQAR----------AEAEAGSPRPDPREALR------- 3052
R G +TVE++ + +++ + + + R AE R RE +
Sbjct: 2924 RTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGER 2983
Query: 3053 ----AATMEVKVGRLRGRAV--PVWDVLASGYVS--GAAREELL----------AEFGSG 3094
A ++ LRG V VW A +S A +++LL A+ G+G
Sbjct: 2984 SVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTG 3043
Query: 3095 TLDLPALTRRLTAIIEEAEEAPGARPQL--------------QDAWRG------------ 3128
+ PA + RLT ++EA A P+ +D + G
Sbjct: 3044 HIIDPATSARLT--VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKG 3101
Query: 3129 --PREPG-------PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQ 3168
PRE G + G D +S R G + ET A +A A A
Sbjct: 3102 LIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSD 3161
Query: 3169 EQTLRDATM-EVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLT 3227
T AT E+Q+ + + + S + AR++EL ++ A
Sbjct: 3162 PSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------R 3209
Query: 3228 RVIEETEERLSKVSFRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV----- 3278
E+T + F+G R V+ EL +S E LR G T+++V
Sbjct: 3210 ETFEKTPVEVPVGGFKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILI 3267
Query: 3279 TEMDSVKRYLEGTSCIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALV 3329
T ++ V+ + +G+ VPA + + E++ + K + G+
Sbjct: 3268 TIVEEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRT 3327
Query: 3330 LLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP-------- 3381
LL+ + ++S+ EA+ G++ LL A+ A DP
Sbjct: 3328 LLQGSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYV 3387
Query: 3382 ------------------------------YTGQQISLFQAMQKDLIVREHGIRLLEAQI 3411
Y+G ISLFQAMQK L++R+HGIRLLEAQI
Sbjct: 3388 HEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQI 3447
Query: 3412 ATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRR 3471
ATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL R
Sbjct: 3448 ATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLER 3507
Query: 3472 CVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWE 3524
CV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+WE
Sbjct: 3508 CVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWE 3567
Query: 3525 LLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA 3572
++ + E++R L++ ++AG +T E + + ++ + + + R A
Sbjct: 3568 VMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTA 3627
Query: 3573 ----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDV 3607
EA + LR T ++ G + G +P ++
Sbjct: 3628 EDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQA 3687
Query: 3608 LASGYVSG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREP 3666
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3688 LKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER- 3744
Query: 3667 GPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVW 3726
A G D Q + +E A R + L + R F P+ V
Sbjct: 3745 --AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV- 3800
Query: 3727 DVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------- 3772
YL++ D+ L + V + V T+ERLS
Sbjct: 3801 -AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGT 3848
Query: 3773 -----------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 3821
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++
Sbjct: 3849 GQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKF 3906
Query: 3822 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 3881
LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L
Sbjct: 3907 LEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGL 3961
Query: 3882 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 3941
+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLL
Sbjct: 3962 KLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLL 4021
Query: 3942 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQ 4001
EAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+Q
Sbjct: 4022 EAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQ 4081
Query: 4002 LLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLF 4061
L+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4082 LMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYEA-- 4135
Query: 4062 YREVSEDRRQDL-LSRYRA--STLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREA 4118
YR+ D + L LS +T+ + S++
Sbjct: 4136 YRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMI----------------------- 4172
Query: 4119 LRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIE 4178
+ R GR + D +A + R+A L ++ +GTL + L+
Sbjct: 4173 ---------IDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS---- 4215
Query: 4179 EAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ 4238
G++G + G + + A +R Q
Sbjct: 4216 -----------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLA 4246
Query: 4239 TLRDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDL 4290
+ D T E G G VS+ + + + + LL AQ G +
Sbjct: 4247 SWSDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI----- 4299
Query: 4291 VAVLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTL 4343
+ T ER ++ +GL ++ ++ + G P T ++
Sbjct: 4300 ------IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4353
Query: 4344 QEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQA 4403
+ ++ +R+LE G++ P D PGR + + +A+ +G + TA L + A
Sbjct: 4354 KGWLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGA 4408
Query: 4404 ATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 4451
+ ++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4409 YSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4457
Score = 852 bits (2202), Expect = 0.0
Identities = 715/2192 (32%), Positives = 1042/2192 (47%), Gaps = 408/2192 (18%)
Query: 1960 VNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEAL----RLLEVQVATGG 2015
+ +E + LK+E T ++ +T QA+Q+ + + ++L R +E + A
Sbjct: 2440 LQQEAKLLQLKSEEMQTVQQEQLLQET----QALQQSFLSEKDSLLQRERFIEQEKAKLE 2495
Query: 2016 VI---DPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERC 2072
+ + +L E ++ + ++ L++ + R+R + + ELQ+
Sbjct: 2496 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2555
Query: 2073 RPQEDTGWVLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVT 2132
+ + +L N+ R+ + +E RA A E+T + K
Sbjct: 2556 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL----------- 2604
Query: 2133 EEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSAII 2192
+ R AL A E +H F G+RR+++A L + I+
Sbjct: 2605 ------------PNGRDALDGPA---------AEAEPEHS-FDGLRRKVSAQRLQEAGIL 2642
Query: 2193 TEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKG 2252
+ E LQ L G +T EL + V+ YL+G S IAG+L+ A + EK+S+Y A+ +
Sbjct: 2643 SAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN-----EKLSVYAALQRQ 2697
Query: 2253 VLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTD 2312
+L PGTAL+LLEAQAA+GF++DPVRN RL+V E V GVVG E+ KLLSAERAVTGY D
Sbjct: 2698 LLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKD 2757
Query: 2313 PYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2372
PYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM
Sbjct: 2758 PYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2817
Query: 2373 NRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL---AGRGSAVHQLSE 2429
NRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L A +G +
Sbjct: 2818 NRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDS 2877
Query: 2430 ELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATL 2489
E R A V+ G QG++V++WE++ + ++R+DLL ++R G +TVE++ +
Sbjct: 2878 EARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKII 2937
Query: 2490 TSLLAQAQAQAR----------AEAEAGSPRPDPREALR-----------AATMEVKVGR 2528
+++ + + + R AE R RE + A ++
Sbjct: 2938 ITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 2997
Query: 2529 LRGRAV--PVWDVLASGYVS--RAAREELL----------AEFGSGTLDLPALTRRLTAI 2574
LRG V VW A +S A +++LL A+ G+G + PA + RLT
Sbjct: 2998 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLT-- 3055
Query: 2575 IEEAEEAPGARPQ--------------------------LQDARRG--PREPG------- 2599
++EA A P+ Q ++G PRE G
Sbjct: 3056 VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQ 3115
Query: 2600 PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQEQTLRDATM-EVQR 2647
+ G D +S R G + ET A +A A A T AT E+Q+
Sbjct: 3116 LSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQ 3175
Query: 2648 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVS 2707
+ + + S + AR++EL ++ A E+T +
Sbjct: 3176 RCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------RETFEKTPVEVPVGG 3223
Query: 2708 FRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV-----TEMDSVKRYLEGTS 2758
F+G R V+ EL +S E LR G T+++V T ++ V+ +
Sbjct: 3224 FKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERL 3281
Query: 2759 CIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDP 2809
+G+ VPA + + E++ + K + G+ LL+ +
Sbjct: 3282 SFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLE 3341
Query: 2810 VRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP---------------------- 2847
++S+ EA+ G++ LL A+ A DP
Sbjct: 3342 DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELH 3401
Query: 2848 ----------------YTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRV 2891
Y+G ISLFQAMQK L++R+HGIRLLEAQIATGG+IDPVHSHRV
Sbjct: 3402 EQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRV 3461
Query: 2892 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL 2951
PVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+TGL +L L
Sbjct: 3462 PVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL 3521
Query: 2952 AGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYREVSEDRRQD 3004
G A EE R A + ++ PG G+ G ++S+WE++ + E++R
Sbjct: 3522 KGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQ 3581
Query: 3005 LLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EAGSPRPDPR 3048
L++ ++AG +T E + + ++ + + + R A EA +
Sbjct: 3582 LMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETY 3641
Query: 3049 EALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYVSG-AAREE 3086
LR T ++ G + G +P ++ L G +S AR
Sbjct: 3642 NLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLL 3701
Query: 3087 LLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQ 3146
L A+ +G L P RLT ++EA P+L D A G D Q
Sbjct: 3702 LEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTGYRDPYTEQ 3756
Query: 3147 REGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRD 3206
+ +E A R + L + R F P+ V YL++ D
Sbjct: 3757 TISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRGYLNKDTHD 3813
Query: 3207 ELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------------KVS 3241
+ L + V + V T+ERLS K++
Sbjct: 3814 Q-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT 3862
Query: 3242 FRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPA 3301
FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSCIAGV V A
Sbjct: 3863 FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSCIAGVFVDA 3920
Query: 3302 KDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVG 3361
+E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEEAV G+VG
Sbjct: 3921 -----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVG 3975
Query: 3362 GEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVH 3421
E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIATGG+IDP
Sbjct: 3976 PEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEE 4035
Query: 3422 SHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLY 3481
SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+QL+ RC+ DP TGL
Sbjct: 4036 SHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLC 4095
Query: 3482 MLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLS 3541
+L L + S+ R V P + G+ +SV+E
Sbjct: 4096 LLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE----------------- 4134
Query: 3542 RYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRA 3601
YR G + + T L Q E S + + R GR
Sbjct: 4135 AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------DGVVKSMIIDRRSGRQ 4180
Query: 3602 VPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWR 3661
+ D +A + +A L ++ +GTL + L+
Sbjct: 4181 YDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS--------------------- 4215
Query: 3662 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG- 3720
G++G + G + + A +R Q + D T E G G
Sbjct: 4216 ------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEET--GPVAGI 4261
Query: 3721 ------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVAVLTRVIEETEER--L 3771
VS+ + + + + LL AQ G + + T ER +
Sbjct: 4262 LDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI-----------IDPSTGERFPV 4310
Query: 3772 SKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTS 3826
+ +GL ++ ++ + G P T ++ + ++ +R+LE
Sbjct: 4311 TDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQY 4370
Query: 3827 CIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVE 3886
G++ P D PGR + + +A+ +G + TA L + A + ++ P L++S +
Sbjct: 4371 LTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYK 4425
Query: 3887 EAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3917
+A+ +V +LL +A ++ GY PY+
Sbjct: 4426 DALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4457
Score = 727 bits (1876), Expect = 0.0
Identities = 710/2292 (30%), Positives = 1038/2292 (45%), Gaps = 316/2292 (13%)
Query: 3017 EELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLAS 3076
EE+ A S A +A E E G R + + LR+ + ++ R R + +
Sbjct: 1903 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE-QAELEAARQRQLAAEEERRR 1961
Query: 3077 GYVSGAAREELLAEFGSGTLDLPAL--TRRLTAIIEEAE------EAPGARPQLQDAWRG 3128
++ L AE + AL RL A +EEA E AR QLQ A
Sbjct: 1962 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEA 2020
Query: 3129 PREPGPAGRGDGDSGRSQREGQGEGETQEAAAA-------AAAARRQEQTLRDATMEVQR 3181
++ A Q+E + + Q+ + A AARR + +A ++ +R
Sbjct: 2021 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2080
Query: 3182 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAV-LTRVIEETEERLSKV 3240
Q R + EA R + A+ A A A L + E+ R ++
Sbjct: 2081 EAAQSR----------RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2130
Query: 3241 SFRGLR-RQVSASELHTSGILGPETLRDLAQGTKTLQ----EVTEMDSVKRYL-EGTSCI 3294
LR +Q + +E+ +TLR AQ + L ++ E D K L E +
Sbjct: 2131 EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRL 2190
Query: 3295 AGVLVPAKDQPGRQEK--------MSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 3346
A Q + E+ M + + AL+L + F+ +
Sbjct: 2191 KAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEK 2250
Query: 3347 LRLSVEEAVAAGVVGGE----------------------IQEKLLSAERAVTGYTDPYTG 3384
++ EEA V E ++EK+ + + A +
Sbjct: 2251 MKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2310
Query: 3385 QQ---ISLFQA---------MQKDLIVREHGI-RLLEA----QIATGGVIDPVHSHRVPV 3427
QQ ++ QA M + L G R LEA Q+ + + +
Sbjct: 2311 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2370
Query: 3428 DVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLL--RRCVPDPDTGLYMLQL 3485
A R D + R A+ + + T E +T VQ L +R D D +
Sbjct: 2371 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI 2430
Query: 3486 AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRA 3545
A +L +E + L + Q Q + + L +SE + LL R R
Sbjct: 2431 AELEREKEKLQQEAK--LLQLKSEEMQTVQQEQLLQETQALQQSFLSE--KDSLLQRERF 2486
Query: 3546 GTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPV- 3604
+L +A+AQ Q R E + + + A+ME R V
Sbjct: 2487 IEQEKAKLEQLFQDEVAKAQ-QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2545
Query: 3605 --WDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRG 3662
+ L +EELLAE + L +L + E+ A ++ +
Sbjct: 2546 RKQEELQQLEQQRRQQEELLAE------ENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2599
Query: 3663 PREPGPAGRG--DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG 3720
+ P GR DG + ++ E +G ++ +A R QE + A E+QR QG
Sbjct: 2600 ATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ----RLQEAGILSAE-ELQR-LAQG 2653
Query: 3721 RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 3780
+ E R E + + G + L+ ++ T E+LS + L+
Sbjct: 2654 HTT----------VDELARREDVRHYLQGRSSIAGLL------LKATNEKLSV--YAALQ 2695
Query: 3781 RQVSA---------SELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 3831
RQ+ + ++ + +L P R L + V + + L + G
Sbjct: 2696 RQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGY 2755
Query: 3832 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 3891
P Q ++S++QAM KG++ + LLEAQ ATG VIDPV + R+ V+ A
Sbjct: 2756 KDPYTGQ-----QISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRR 2810
Query: 3892 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEA--QIATGG 3949
G E+ L G+ DP T + ++ Q +++ + E G+ LL + A GG
Sbjct: 2811 GYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGG 2870
Query: 3950 VI--------DPVHSHRVPVDVAYRRG------------YFDEEMNRVLADPSDDTKGFF 3989
+ D V +G YF E R L +
Sbjct: 2871 ELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITV 2930
Query: 3990 DPNTHENLTYVQL-----------LRRCVPDP--------DTGLYMLQLAGRGSAVHQLS 4030
+ +T V+ LR VP D LY QL +V ++
Sbjct: 2931 EKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQ-QLQRGERSVRDVA 2989
Query: 4031 E--ELRCALRDARVTPGSGALQ-GQSVSVWELLFYREVSEDRRQDLLSRYRASTLTVEEL 4087
E +R ALR A V G + GQ +S++ L ++DLL A L +
Sbjct: 2990 EVDTVRRALRGANVIAGVWLEEAGQKLSIYNAL---------KKDLLPSDMAVALLEAQA 3040
Query: 4088 GAT-LTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGR--LRGRAVPVWDVLAS 4144
G + A+ AG P+ E L +A V R G++V ++ L
Sbjct: 3041 GTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKK 3100
Query: 4145 GYVSRAAREELL-AEFGSGTLDLPALTRRLTAII--------EEAEEAPGARPQLQDAWR 4195
G + R LL A+ +G + P+ + R+ + EE A A A+
Sbjct: 3101 GLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYS 3160
Query: 4196 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ---------TLRDATME 4246
P PA G+ + R Q G + + AA RQE+ T +E
Sbjct: 3161 DPSTGEPATYGELQ--QRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVE 3218
Query: 4247 VQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEE-RL 4305
V G F+GR V+VW+++ S Y + +R ELL Q G + + ++ +L ++EE E R
Sbjct: 3219 VPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQ 3278
Query: 4306 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 4365
++SF GLR V ASEL SG+L L G T+++++E+ SV+ L+G+ C+AG+
Sbjct: 3279 ERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGI 3338
Query: 4366 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 4425
+ +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL V EAV A
Sbjct: 3339 YLE-----DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKA 3393
Query: 4426 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 4485
GVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATGG+I
Sbjct: 3394 GVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGII 3453
Query: 4486 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 4545
DPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+
Sbjct: 3454 DPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPE 3513
Query: 4546 TGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYRE 4598
TGL +L L G A EE R A + ++ PG G+ G ++S+WE++
Sbjct: 3514 TGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDL 3573
Query: 4599 VSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EA 4642
+ E++R L++ ++AG +T E + + ++ + + + R A EA
Sbjct: 3574 IPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEA 3633
Query: 4643 GSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYV 4681
+ LR T ++ G + G +P ++ L G +
Sbjct: 3634 RIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLL 3693
Query: 4682 SG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRG 4740
S AR L A+ +G L P RLT ++EA P+L D A G
Sbjct: 3694 SAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTG 3748
Query: 4741 DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSS 4800
D Q + +E A R + L + R F P+ V
Sbjct: 3749 YRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRG 3805
Query: 4801 YLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------- 4840
YL++ D+ L + V + V T+ERLS
Sbjct: 3806 YLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLP 3854
Query: 4841 -----KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSC 4895
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSC
Sbjct: 3855 LSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSC 3912
Query: 4896 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 4955
IAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEE
Sbjct: 3913 IAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 3967
Query: 4956 AVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 5015
AV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIAT
Sbjct: 3968 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4027
Query: 5016 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRAT 5075
GG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTYLQL++R
Sbjct: 4028 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4087
Query: 5076 LDPETGLLFLSL 5087
DP+TGL L L
Sbjct: 4088 TDPQTGLCLLPL 4099
Score = 619 bits (1597), Expect = e-176
Identities = 476/1531 (31%), Positives = 736/1531 (48%), Gaps = 227/1531 (14%)
Query: 40 ARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKAL 99
A IAGV++E +GQ S+Y A+++ LLP+ + ALLEAQA TG ++D A L V +A+
Sbjct: 3001 ANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEAV 3060
Query: 100 QQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGG 159
+ GLVG E EKLL+AE+A TGY DPY G+ ++LFQA+ K ++ R G L+ QL+TGG
Sbjct: 3061 RAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTGG 3120
Query: 160 LVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCV 219
+VDP++ V + AC +G LD ET LS P + +P+T E TY +L +RC
Sbjct: 3121 IVDPSKSHRVPLDVACARGCLDEETSRALS--APRADAKAYSDPSTGEPATYGELQQRCR 3178
Query: 220 RAPGSGLALLPL------------------KITFRS----------MGGAVSAAELLEVG 251
+GL+LLPL + TF G V+ EL+
Sbjct: 3179 PDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISSE 3238
Query: 252 ILD-EQAVQGLREGRLAAV--------------DVSARAEVRRYLEGTGS--------VA 288
EQ + LR+ R V +V + R G + +
Sbjct: 3239 YFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLAS 3298
Query: 289 GVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAG-- 346
GV+ + + + + L +G+ LL+ + T +++ + EA+R G
Sbjct: 3299 GVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGLL 3358
Query: 347 -----------------LVSPELHEQLLVAE-------------------QAVTGHHDPF 370
LV P +++L V E +AVTG+ DP+
Sbjct: 3359 RATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDPY 3418
Query: 371 SGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQR 430
SGS I LFQAM+KGLV R +RLL+AQ+ATGG++ P R+P++ A + G E+ R
Sbjct: 3419 SGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMNR 3478
Query: 431 QLSQ-----AGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPP-FIK 484
L+ G F TH L Y QLL CV DPETGL LPL G + + + +
Sbjct: 3479 VLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVETTQVYTE 3538
Query: 485 YSTRQALSTATATV-SVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAA 543
TR+A + G G +SLWE++ S+ I EQRA L +Q G ++ E++
Sbjct: 3539 EETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMII 3598
Query: 544 ELSATLEQAAATAR---VTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLA 600
+ +E+ + ++ +R +T +L +A II + Y L G + ++
Sbjct: 3599 IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAE 3658
Query: 601 SAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANK 660
SA YL GTG +AG+ LPGS++ LSIY+A KGLL A +LLEAQAATGF++DP +
Sbjct: 3659 SAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGE 3718
Query: 661 GHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLL 720
+V+EA+R ++GP++ +LLSAERAVTGY DPYT Q ISLFQAM+K LI E +RLL
Sbjct: 3719 RLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLL 3778
Query: 721 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQ 780
+AQ+ATGG++DP +P++VAY+RGY ++ + L +PS + + + DP+T E L+Y Q
Sbjct: 3779 DAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQ 3837
Query: 781 LLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSE 840
LL RC RD TG LLPLS A + F+ L ++++ EL+ S+
Sbjct: 3838 LLRRCRRDDGTGQLLLPLS--------DARKLTFRGL----------RKQITMEELVRSQ 3879
Query: 841 YFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQ 900
E QL E + K LE T A + + A + R++V+Q ++ GII
Sbjct: 3880 VMDEATALQLREGLTSIEEVTKNLQKFLEG-TSCIAGVFVDATKERLSVYQAMKKGIIRP 3938
Query: 901 QLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVA 960
++L A G V G +L++ +A+R ++GP
Sbjct: 3939 GTAFELLEAQ-------------------AATGYVIDPIKGLKLTVEEAVRMGIVGPEFK 3979
Query: 961 LALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQV 1020
LL A+ A DP+S + +S+ +A+++G++ + RL A+ A G DP ++
Sbjct: 3980 DKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRL 4039
Query: 1021 SVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSS 1080
V A K+GL E L + T G DP + +L
Sbjct: 4040 PVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENL---------------------- 4077
Query: 1081 SETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPT--EEQVQRSLQAVPGA 1138
+Y QL+E C D +GL LLPL E T + V++ +
Sbjct: 4078 -------------TYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDP 4124
Query: 1139 KDGTSLWDLLSSCHFTEEQRRGLLE-----DVQEGRTTVPQLLASVQRWVQETKLLAQAR 1193
+ G + E R+GL++ ++ E ++ S V ++ ++ +
Sbjct: 4125 ETGKEM-------SVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRR- 4176
Query: 1194 VMVPGPRGEVPAVWLLDAGIITQETLEALAQGTQSPAQVAE------------------- 1234
G + ++ + +I + L+ GT S + A+
Sbjct: 4177 ---SGRQYDIDDA--IAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSS 4231
Query: 1235 -----QPAV---KACLWG-----TGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLE 1281
PAV + W TG VAG+L + K SI +A+ L+ GQRLLE
Sbjct: 4232 SSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLE 4291
Query: 1282 AQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQA 1341
AQ +G ++DP +R V DAV GLV + + +++ A++A G+ DP ++ +S QA
Sbjct: 4292 AQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQA 4351
Query: 1342 MEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNK 1401
++KG + G L+VQ TGG+++P +P A + G +D +T+Q L V +K
Sbjct: 4352 LKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSK 4411
Query: 1402 FFFDPSARDQVTYQQLRERCVCDSETGLLLL 1432
+ P + +++Y+ +R + + TGL LL
Sbjct: 4412 YLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4442
Score = 350 bits (897), Expect = 3e-95
Identities = 288/927 (31%), Positives = 451/927 (48%), Gaps = 110/927 (11%)
Query: 4243 ATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE 4302
AT+ G+FQG+ V++W+++ S Y + +R +LL Q G + + ++ ++ V+EE E
Sbjct: 2886 ATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE 2945
Query: 4303 ERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCI 4362
++ ++ F GLR V A+EL S ++ E + L +G +++++V E+D+V+R L G + I
Sbjct: 2946 QK-GRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRALRGANVI 3004
Query: 4363 AGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEA 4422
AGV + Q K+SIY A+ K +L A+ LLEAQA TG +IDP + RL+V+EA
Sbjct: 3005 AGVWLEEAGQ-----KLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEA 3059
Query: 4423 VAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 4482
V AG+VG E EKLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++TG
Sbjct: 3060 VRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTG 3119
Query: 4483 GVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVP 4542
G++DP SHRVP+DVA RG DEE +R L+ P D K + DP+T E TY +L +RC P
Sbjct: 3120 GIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRCRP 3179
Query: 4543 DPDTGLYMLQLAGRGSAVHQLSEELRCALRDARV---TPGS---GALQGQSVSVWELLFY 4596
D TGL +L L+ + + Q EEL L+ TP G +G++V+VWEL+
Sbjct: 3180 DQLTGLSLLPLSEKAARARQ--EELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3237
Query: 4597 REVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAE-AGSPRPDPREAL-- 4653
+ ++RQ+LL ++R G +TVE++ L +++ + + + +G P P L
Sbjct: 3238 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3297
Query: 4654 -----RAATMEVKVGR---------------LRGRA-------------VPVWDVLASGY 4680
RA ++K G+ L+G V +++ + G
Sbjct: 3298 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3357
Query: 4681 VSGAAREELL-AEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGR 4739
+ LL A+ +G L P +RL + EA +A P+L + E G
Sbjct: 3358 LRATTAALLLEAQAATGFLVDPVRNQRL--YVHEAVKAGVVGPELHEQLLSA-EKAVTGY 3414
Query: 4740 GDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQF----QGRPVSVWD 4795
D SG + Q A ++ +R ++ G V V
Sbjct: 3415 RDPYSGSTISLFQ---------AMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3465
Query: 4796 VLFSSYLSEARRDELLAQHAAGALGLPD--------LVAVLTRVIEETEERLSKVSFRGL 4847
Y SE + +LA + G D +L R +E+ E L + +G
Sbjct: 3466 AYQRGYFSE-EMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGA 3524
Query: 4848 RRQ--VSASELHTSGILG---PETLRDLAQG------TKTLQEVTEMDSVK--------- 4887
+ V ++++T ET D+ G T +L EV + D +
Sbjct: 3525 EKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMA 3584
Query: 4888 -----RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFV 4942
R + I + + K + RQ+ ++ Y V R TA L EA+ +
Sbjct: 3585 DFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDY----VRRRLTAEDLFEARIISLET 3640
Query: 4943 IDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 5002
+ +R S+ EA+ A E L +V G P + Q +S++QA++K L+
Sbjct: 3641 YNLLREGTRSLREALEA-----ESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSA 3695
Query: 5003 EHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTH 5062
E LLEAQ ATG ++DPV R+ VD A R+G E++ L G+ DP T
Sbjct: 3696 EVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTE 3755
Query: 5063 ENLTYLQLLQRATLDPETGLLFLSLSL 5089
+ ++ Q +++ + E L L L
Sbjct: 3756 QTISLFQAMKKELIPTEEALRLLDAQL 3782
Score = 347 bits (889), Expect = 2e-94
Identities = 202/360 (56%), Positives = 242/360 (67%), Gaps = 25/360 (6%)
Query: 4746 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 4801
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2512 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2571
Query: 4802 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 4848
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2572 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2628
Query: 4849 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 4908
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2629 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2685
Query: 4909 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 4968
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2686 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2743
Query: 4969 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 5028
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2744 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2803
Query: 5029 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLS 5088
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLL+R DPETGL L L+
Sbjct: 2804 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2863
Score = 254 bits (648), Expect = 2e-66
Identities = 137/307 (44%), Positives = 206/307 (67%), Gaps = 8/307 (2%)
Query: 4784 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE--ERLSK 4841
G G +S+W+V+ S + E +R +L+A AG + ++ ++ +IE+TE +
Sbjct: 3556 GSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGL 3615
Query: 4842 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 4901
S+ +RR+++A +L + I+ ET L +GT++L+E E +S YL GT +AGV +
Sbjct: 3616 ASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYL 3675
Query: 4902 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 4961
P G ++ +SIYQA+ KG+L A +LLEAQAATGF++DPV+ RL+V+EAV G+
Sbjct: 3676 P-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGL 3730
Query: 4962 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 5021
VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI E +RLL+AQ+ATGG++DP
Sbjct: 3731 VGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDP 3790
Query: 5022 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETG 5081
+P++VAY+RGY +++ + L++PS + + + DP+T E L+Y QLL+R D TG
Sbjct: 3791 RLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQLLRRCRRDDGTG 3849
Query: 5082 LLFLSLS 5088
L L LS
Sbjct: 3850 QLLLPLS 3856
Score = 107 bits (267), Expect = 3e-22
Identities = 73/212 (34%), Positives = 111/212 (52%), Gaps = 5/212 (2%)
Query: 4347 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4406
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4243 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4297
Query: 4407 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 4466
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4298 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4357
Query: 4467 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 4526
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4358 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4417
Query: 4527 THENLTYVQLLRRCVPDPDTGLYMLQLAGRGS 4558
T ++Y L R + + TGL +L+ A + +
Sbjct: 4418 TKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4449
Score = 107 bits (266), Expect = 4e-22
Identities = 73/210 (34%), Positives = 109/210 (51%), Gaps = 5/210 (2%)
Query: 4881 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4940
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4243 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4297
Query: 4941 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 5000
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4298 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4357
Query: 5001 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 5060
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4358 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4417
Query: 5061 THENLTYLQLLQRATLDPETGLLFLSLSLQ 5090
T ++Y L R+ ++ TGL L + Q
Sbjct: 4418 TKLKISYKDALDRSMVEEGTGLRLLEAAAQ 4447
Score = 105 bits (261), Expect = 2e-21
Identities = 69/217 (31%), Positives = 114/217 (52%), Gaps = 3/217 (1%)
Query: 13 GTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQ 72
G++S+ S P L + + P + +AG+ + + S+ AM + L+ GQ
Sbjct: 4229 GSSSSYPIS-PAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQ 4287
Query: 73 ALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLA 132
LLEAQA TGG++D + G+ PV+ A+ +GLV + +++ A++A G+ DP K++
Sbjct: 4288 RLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMS 4347
Query: 133 LFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLLDRETWHKLSELE 192
QA+ K + GQ +LEVQ TGGL++P V + A +G +D T KL ++
Sbjct: 4348 AAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV- 4406
Query: 193 PGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALL 229
G P T +++Y L+R + G+GL LL
Sbjct: 4407 -GAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4442
Score = 70.5 bits (171), Expect = 4e-11
Identities = 61/227 (26%), Positives = 102/227 (44%), Gaps = 17/227 (7%)
Query: 4832 IEETEERLS--KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 4889
++ T+ERLS + +G+ R +A EL + + + T++E M V
Sbjct: 3918 VDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPE 3977
Query: 4890 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 4949
+ A V P + +S++QAM KG++ + LLEAQ ATG +IDP +
Sbjct: 3978 FKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESH 4037
Query: 4950 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 5009
RL VE A G+ E+ E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4038 RLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLL 4097
Query: 5010 -------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 5041
E + ++ ++DP + V AYR+G D +
Sbjct: 4098 PLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4144
Score = 60.8 bits (146), Expect = 3e-08
Identities = 32/119 (26%), Positives = 61/119 (51%)
Query: 4971 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 5030
L ++ G T +++S++ A+Q+ L+ + LLEAQ A+G ++DPV + R+ V+
Sbjct: 2670 LQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVN 2729
Query: 5031 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSL 5089
A + G E++ L G+ DP T + ++ Q +Q+ + E G+ L +
Sbjct: 2730 EAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQI 2788
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4254 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4310
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4178 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4233
Query: 4311 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4359
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4234 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4293
Query: 4360 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4386
+C G++ P+ + P + KMS QA+
Sbjct: 4294 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4353
Query: 4387 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4446
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4354 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4413
Query: 4447 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 4487
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4414 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4455
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4788 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4844
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4178 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4233
Query: 4845 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4893
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4234 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4293
Query: 4894 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4920
+C G++ P+ + P + KMS QA+
Sbjct: 4294 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4353
Query: 4921 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4980
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4354 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4413
Query: 4981 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 5021
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4414 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4455
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 1268 bits (3280), Expect = 0.0
Identities = 798/1967 (40%), Positives = 1134/1967 (57%), Gaps = 218/1967 (11%)
Query: 1511 AAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLEGG 1570
AAE +P + +F GLR++VSA+ L A ++S + L L+QG TTV E+A + V+ L+G
Sbjct: 2623 AAEAEP-EHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGR 2681
Query: 1571 NFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFK 1630
+ IAG+L++ T E++S+ AL+R +L PGTAL+LLEAQAA+GF++DP NR+LTV EA K
Sbjct: 2682 SSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVK 2741
Query: 1631 AGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGI 1690
G+ G E + KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGG+
Sbjct: 2742 EGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGV 2801
Query: 1691 IDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 1750
IDPVHSHRVPVDVAYR GYFDEEMNR+LADPSDDTKGFFDPNTHENLTYLQLLERCVEDP
Sbjct: 2802 IDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 2861
Query: 1751 ETGLYLLQI---IKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTE 1807
ETGL LL + KG VY + R V + T G+F + V+ W++++S YFT
Sbjct: 2862 ETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTA 2921
Query: 1808 DRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLFNSRVIDQ 1867
+++R+L++++ +EK+++II T +EE E Q + +R V AA+L SRVID+
Sbjct: 2922 EQRRDLLRQFRTGRITVEKIIKIIITVVEEQE-QKGRLCFEGLRSLVPAAELLESRVIDR 2980
Query: 1868 KTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFA 1927
+ L+ G + ++ ++ V+ L G++ IAGV + + +S++ A +K+L+P+ A
Sbjct: 2981 ELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMA 3040
Query: 1928 TWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTI 1987
LLEAQA TG ++DP T +L+VDEAV GLV E E+LL AE+A TGYRDP TG ++
Sbjct: 3041 VALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSV 3100
Query: 1988 PLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQ 2047
LFQA++K LI + + LRLL+ Q++TGG++DP HR+PL+ A RGCL ++ +S
Sbjct: 3101 SLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAP 3160
Query: 2048 KHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVN-KAAR---DSEHIDDETRRAL 2103
+ K + DP+T E +Y ELQ+RCRP + TG L P++ KAAR + + + + R
Sbjct: 3161 RADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETF 3220
Query: 2104 EAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIE 2163
E VE+ VG F+G+ T+W L++SEY T E++ +L+R +RT + ++ V ++++ ++E
Sbjct: 3221 EKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRT-GKVTVEKVIKILITIVE 3279
Query: 2164 KQET-SNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEG 2222
+ ET + L F G+R + ASELL+S +++ + L+ G++T ++L E V+ L+G
Sbjct: 3280 EVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQG 3339
Query: 2223 TSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLS 2282
+ C+AG+ + +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL
Sbjct: 3340 SGCLAGIYL-----EDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLY 3394
Query: 2283 VEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQ 2342
V E V AGVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQ
Sbjct: 3395 VHEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQ 3454
Query: 2343 IATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLR 2402
IATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL
Sbjct: 3455 IATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLE 3514
Query: 2403 RCVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVW 2455
RCV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+W
Sbjct: 3515 RCVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLW 3574
Query: 2456 ELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAE 2503
E++ + E++R L++ ++AG +T E + + ++ + + + R
Sbjct: 3575 EVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLT 3634
Query: 2504 A----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWD 2538
A EA + LR T ++ G + G +P ++
Sbjct: 3635 AEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQ 3694
Query: 2539 VLASGYVS-RAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDARRGPRE 2597
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3695 ALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER 3752
Query: 2598 PGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSV 2657
A G D Q + +E A R + L + R F P+ V
Sbjct: 3753 ---AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV 3808
Query: 2658 WDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS------------- 2704
YL++ D+ L + V + V T+ERLS
Sbjct: 3809 --AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDG 3855
Query: 2705 ------------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKR 2752
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ ++++
Sbjct: 3856 TGQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQK 3913
Query: 2753 YLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 2812
+LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++
Sbjct: 3914 FLEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKG 3968
Query: 2813 LRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRL 2872
L+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRL
Sbjct: 3969 LKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRL 4028
Query: 2873 LEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYV 2932
LEAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+
Sbjct: 4029 LEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYL 4088
Query: 2933 QLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELL 2992
QL+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4089 QLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE-- 4142
Query: 2993 FYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALR 3052
YR G + + T L Q E S
Sbjct: 4143 ---------------AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------D 4173
Query: 3053 AATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEA 3112
+ + R GR + D +A + +A L ++ +GTL + L+
Sbjct: 4174 GVVKSMIIDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS------ 4223
Query: 3113 EEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTL 3172
G++G + G + + A +R Q +
Sbjct: 4224 ---------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASW 4256
Query: 3173 RDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVA 3224
D T E G G VS+ + + + + LL AQ G +
Sbjct: 4257 SDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI------- 4307
Query: 3225 VLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQE 3277
+ T ER ++ +GL ++ ++ + G P T ++ +
Sbjct: 4308 ----IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKG 4363
Query: 3278 VTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 3337
++ +R+LE G++ P D PGR + + +A+ +G + TA L + A +
Sbjct: 4364 WLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYS 4418
Query: 3338 GFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3383
++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4419 KYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4465
Score = 1127 bits (2914), Expect = 0.0
Identities = 724/1911 (37%), Positives = 1065/1911 (55%), Gaps = 110/1911 (5%)
Query: 522 EQRAMLAQQYQEGTLSVEKL-AAELSAT---------LEQAAATARV--TFSGLRDTVTP 569
EQ +L +Q++ E++ A++++AT L+ AA A +F GLR V+
Sbjct: 2582 EQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSA 2641
Query: 570 GELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEA 629
L +A I+ + +RL G T ++ + YLQG IAGLLL + E+LS+Y A
Sbjct: 2642 QRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAA 2701
Query: 630 RCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVT 689
+ LL PGTALILLEAQAA+GF++DP N+ +V EA++ V+GP++ KLLSAERAVT
Sbjct: 2702 LQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVT 2761
Query: 690 GYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 749
GY DPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF
Sbjct: 2762 GYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 2821
Query: 750 DQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSP----- 804
D+ +N +L DPSDDTKGFFDPNTHENLTYLQLLERCV DPETGL LLPL+ +
Sbjct: 2822 DEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELV 2881
Query: 805 LVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQV 864
DS + F+ +S +G+FQG+ V+ WE+INSEYF+ +RR LLR++R +T+ ++
Sbjct: 2882 YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKI 2941
Query: 865 AKLLEA---ETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDG 921
K++ E +++ + LRS V +LLE+ +ID++L Q+ G S + +D
Sbjct: 2942 IKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDT 3001
Query: 922 VRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPES 981
VRR L G + GV L +GQ+LS+Y A+++ LL +A+ALLEAQA TG I+DP +
Sbjct: 3002 VRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSAR 3061
Query: 982 LSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLE 1041
L+VDEAVR G+VGPE + +L AE A+ G+RDP++G+ VS+FQA+KKGLIP EQ RLL+
Sbjct: 3062 LTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLD 3121
Query: 1042 AQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSS---SSETFPTPDGQGRTSYAQL 1098
AQ++TGGI+DP+ H +P+ VA RG +D+E ALS+ ++ + P +Y +L
Sbjct: 3122 AQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGEL 3181
Query: 1099 LEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQA------------VPGAKDGT-SLW 1145
+ C D+ +GL LLPL E A A +E++ LQA V G K T ++W
Sbjct: 3182 QQRCRPDQLTGLSLLPLSEKA-ARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVW 3240
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+SS +FT EQR+ LL + G+ TV +++ + V+E + L Q R+ G R VPA
Sbjct: 3241 ELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPA 3300
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQA 1265
LL +G++++ E L G + ++E +V+ L G+GC+AG+ L+ + K SI +A
Sbjct: 3301 SELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEA 3360
Query: 1266 VRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAA 1325
+R GLL LLEAQ A+GFLVDP+ NQRL V +AVK G+VG EL EQL AE+A
Sbjct: 3361 MRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVT 3420
Query: 1326 GYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLL 1385
GY DPYS +++SL+QAM+KGLV + G+ LL+ Q+ATGG++DPVH +P A + G
Sbjct: 3421 GYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYF 3480
Query: 1386 DTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDH 1445
+ ++VL D K FFDP+ + +TY+QL ERCV D ETGL LLPL EV +
Sbjct: 3481 SEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVET 3540
Query: 1446 TAV--------ALRAMKVPV-STGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAA 1496
T V A ++ + G G ++SLW+++ S+ + ++R +L+A ++GR
Sbjct: 3541 TQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVT 3600
Query: 1497 ALRQVVSAVTALVEAAE--RQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTV 1554
R ++ + ++E E RQ A++ +R++++A DLF A++IS +T + L +GT ++
Sbjct: 3601 KERMII-IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSL 3659
Query: 1555 KEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFI 1614
+E E +S L G +AGV + G+++ +SI +AL++ +L A +LLEAQAATGF+
Sbjct: 3660 REALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFL 3719
Query: 1615 IDPAENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 1674
+DP + +LTV+EA + G+ G E + +LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3720 LDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPT 3779
Query: 1675 EHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTH 1734
E +RLL+AQ+ATGGI+DP +P++VAY+ GY +++ + L++PS+ + + DP+T
Sbjct: 3780 EEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSE-VRSYVDPSTD 3838
Query: 1735 ENLTYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVV 1794
E L+Y QLL RC D TG LL + A+ R + +
Sbjct: 3839 ERLSYTQLLRRCRRDDGTGQLLLPL--------------------SDARKLTFRGLRKQI 3878
Query: 1795 SFWDLLSSPYFTED---RKRELIQEYGAQSGGLEKLLE-------IITTTIEETETQNQG 1844
+ +L+ S E + RE + + L+K LE + +E + Q
Sbjct: 3879 TMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQA 3938
Query: 1845 IKVAAIRG----EVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIA 1900
+K IR E+ A VID L V + E L +
Sbjct: 3939 MKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVT 3998
Query: 1901 GVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLV 1960
G P + +++SL +A +K LI LLEAQ ATG ++DP +L V+ A GL
Sbjct: 3999 GYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLF 4058
Query: 1961 NEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLL------------- 2007
+EE+ E L G+ DP T + + Q M++ + + L LL
Sbjct: 4059 DEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSS 4118
Query: 2008 --EVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSY 2065
V+ ++DP+ + + AYR+G + Y +S+Q+ + ++ V
Sbjct: 4119 KSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKS 4178
Query: 2066 RELQERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALE----AEQVEITVGRFRGQKPT 2121
+ R Q D + + K D +D L A+ + G FR + +
Sbjct: 4179 MIIDRRSGRQYD---IDDAIAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSS 4235
Query: 2122 LWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQI 2181
+ + + + QL + T L E +EK S + + I
Sbjct: 4236 VGSSSSYPISPAVSRTQLA-SWSDPTEETGPVAGILDTETLEK--VSITEAMHRNLVDNI 4292
Query: 2182 TASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQE 2241
T LL + T ++ R + + V + + +A + P +
Sbjct: 4293 TGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKT 4352
Query: 2242 KMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLL 2301
KMS QA+ KG L LE Q TG +I+P R+ ++E + G V + +KL
Sbjct: 4353 KMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLR 4412
Query: 2302 SAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 2351
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4413 DVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4463
Score = 1054 bits (2725), Expect = 0.0
Identities = 630/1557 (40%), Positives = 924/1557 (59%), Gaps = 83/1557 (5%)
Query: 869 EAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCG 928
EAE + D LR +V+ +L EAGI+ + L ++ G + + L + VR YL G
Sbjct: 2625 EAEPEHSFD----GLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQG 2680
Query: 929 LGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAV 988
++ G+ L + ++LS+Y A++++LL P AL LLEAQAA+G ++DP L+V+EAV
Sbjct: 2681 RSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAV 2740
Query: 989 RRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGG 1048
+ GVVGPEL+ +L AE A+ G++DP++G+Q+S+FQAM+KGLI E RLLEAQ+ATGG
Sbjct: 2741 KEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGG 2800
Query: 1049 IIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRD 1105
+IDP H +P+ VA +RGY D+EM L+ S+ F P+ +Y QLLE C D
Sbjct: 2801 VIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVED 2860
Query: 1106 ETSGLHLLPLPESAPA--------LPTEEQVQRSLQAVPGAK---DGTSLWDLLSSCHFT 1154
+GL LLPL + A + +++ + P K ++W++++S +FT
Sbjct: 2861 PETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFT 2920
Query: 1155 EEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDAGII 1214
EQRR LL + GR TV +++ + V+E + + R+ G R VPA LL++ +I
Sbjct: 2921 AEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE--QKGRLCFEGLRSLVPAAELLESRVI 2978
Query: 1215 TQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTG 1274
+E + L +G +S VAE V+ L G +AGV L+ +G K SI A++ LLP+
Sbjct: 2979 DRELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSD 3038
Query: 1275 LGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRA 1334
+ LLEAQ +G ++DP + RL+V++AV+ GLVG E E+L AE+A GY DPY+
Sbjct: 3039 MAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQ 3098
Query: 1335 SLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLT 1394
S+SL+QA++KGL+P+ +GL LL QL+TGG+VDP +P AC G LD +TS+ L+
Sbjct: 3099 SVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALS 3158
Query: 1395 AVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMK 1454
A D K + DPS + TY +L++RC D TGL LLPL + L+A +
Sbjct: 3159 APRADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARE 3218
Query: 1455 ------VPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVTAL 1508
V V G FKG +V++W+L+ SEY A++R+EL+ R+G+ + + +T +
Sbjct: 3219 TFEKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIV 3278
Query: 1509 VEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
E + + +F GLR V A +L + ++SR ++L G TTVK+++E+ SV+ L+
Sbjct: 3279 EEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQ 3338
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G +AG+ ++ T+E++SI EA+RR +LR TA +LLEAQAATGF++DP N++L V EA
Sbjct: 3339 GSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEA 3398
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 1688
KAG+ G E + +LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATG
Sbjct: 3399 VKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATG 3458
Query: 1689 GIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVE 1748
GIIDPVHSHRVPVDVAY+ GYF EEMNR+LADPSDDTKGFFDPNTHENLTY QLLERCVE
Sbjct: 3459 GIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVE 3518
Query: 1749 DPETGLYLLQI--IKKGE----NYVYINEATRHVLQSRTAKM-RVGRFADQVVSFWDLLS 1801
DPETGL LL + +K E VY E TR + + G +S W+++
Sbjct: 3519 DPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQ 3578
Query: 1802 SPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETE-TQNQGI-KVAAIRGEVTAADL 1859
S E+++ +L+ ++ A E+++ II IE+TE + QG+ +R +TA DL
Sbjct: 3579 SDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDL 3638
Query: 1860 FNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRK 1919
F +R+I +T + LR G + E YL G+ +AGV +P +R+ +S+++A +K
Sbjct: 3639 FEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKK 3698
Query: 1920 ELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYR 1979
L+ A A LLEAQAATGFLLDP ++L+VDEAV GLV EL +RLL AERA TGYR
Sbjct: 3699 GLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYR 3758
Query: 1980 DPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKD 2039
DP T TI LFQAM+K+LI EALRLL+ Q+ATGG++DP+ LPLE AY+RG L+KD
Sbjct: 3759 DPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKD 3818
Query: 2040 IYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDET 2099
+ +S+ +R +VDP+T E++SY +L RCR + TG +L P++ A + +
Sbjct: 3819 THDQLSEPSEVRS-YVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT------- 3870
Query: 2100 RRALEAEQVEITVGRFRG--QKPTLWALLNSEYVTEEKKLQL------VRMYRTHTRRAL 2151
FRG ++ T+ L+ S+ + E LQL + + ++ L
Sbjct: 3871 ---------------FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFL 3915
Query: 2152 QTVAQLILELIE--KQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQE 2209
+ + + ++ K+ S +GI R TA ELL + T ++ ++ + T +E
Sbjct: 3916 EGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 3975
Query: 2210 LMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 2269
+ V + A V P + +S++QAM KG++ + LLEAQ AT
Sbjct: 3976 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4035
Query: 2270 GFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDL 2329
G +IDP + RL VE G+ E+ E L G+ DP T + ++ Q M++ +
Sbjct: 4036 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4095
Query: 2330 IVREHGIRLL-------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 2371
+ G+ LL E + ++ ++DP + V AYR+G D +
Sbjct: 4096 TDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4152
Score = 999 bits (2583), Expect = 0.0
Identities = 666/1843 (36%), Positives = 989/1843 (53%), Gaps = 126/1843 (6%)
Query: 234 TFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLL 293
+F + VSA L E GIL + +Q L +G +++ R +VR YL+G S+AG++L
Sbjct: 2631 SFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLK 2690
Query: 294 PEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELH 353
K S + A LL GTAL LLEAQAA+ L+DP+ +RL V+EAV+ G+V PELH
Sbjct: 2691 ATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELH 2750
Query: 354 EQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRL 413
+LL AE+AVTG+ DP++G QI LFQAM+KGL+ R +RLL+AQ+ATGG++ P R+
Sbjct: 2751 HKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRV 2810
Query: 414 PLEAALRCGCLDEDTQRQLSQA-----GSFSDGTHGGLRYEQLLALCVTDPETGLAFLPL 468
P++ A R G DE+ R L+ G F TH L Y QLL CV DPETGL LPL
Sbjct: 2811 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPL 2870
Query: 469 SG-GPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAML 527
+ +GGE + R AT + GKF+G+ V++WE++ SE ++EQR L
Sbjct: 2871 TDKAAKGGELV---YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDL 2927
Query: 528 AQQYQEGTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLE 587
+Q++ G ++VEK+ + +E+ R+ F GLR V ELL++ +ID++LY++L+
Sbjct: 2928 LRQFRTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQ 2987
Query: 588 HGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQ 647
G+ + +DV + + +R L+G IAG+ L + ++LSIY A K LL A+ LLEAQ
Sbjct: 2988 RGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQ 3047
Query: 648 AATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQ 707
A TG IIDP + +V+EA+RA ++GP+ KLLSAE+AVTGY DPYTGQ +SLFQA++
Sbjct: 3048 AGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALK 3107
Query: 708 KGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGF 767
KGLI RE G+RLL+AQ++TGG++DP SHRVP+DVA RG D+ + L P D K +
Sbjct: 3108 KGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAY 3167
Query: 768 FDPNTHENLTYLQLLERCVRDPETGLYLLPLS-----STQSPLV-DSATQQAFQNLLLSV 821
DP+T E TY +L +RC D TGL LLPLS + Q L + ++ F+ + V
Sbjct: 3168 SDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEV 3227
Query: 822 KYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQVAKLL-----EAETQRQA 876
G F+G+ V+ WELI+SEYF+ +R++LLR++R +VT+ +V K+L E ET RQ
Sbjct: 3228 PVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQE 3287
Query: 877 DIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVR 936
+ LR+ V +LL +G++ + +Q+ G + + L + VR L G G + G+
Sbjct: 3288 RLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIY 3347
Query: 937 LLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPE 996
L + +++S+Y+AMR+ LL A LLEAQAATG ++DP + L V EAV+ GVVGPE
Sbjct: 3348 LEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPE 3407
Query: 997 LYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHH 1056
L+ +L AE A+ G+RDP+SG +S+FQAM+KGL+ + RLLEAQ+ATGGIIDP H
Sbjct: 3408 LHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSH 3467
Query: 1057 HLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRDETSGLHLL 1113
+P+ VA QRGY +EM L+ S+ F P+ +Y QLLE C D +GL LL
Sbjct: 3468 RVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLL 3527
Query: 1114 PLPESAPA-------LPTEEQVQRSLQA----VPG----AKDGTSLWDLLSSCHFTEEQR 1158
PL + A + TEE+ +R+ + +PG SLW+++ S EEQR
Sbjct: 3528 PLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQR 3587
Query: 1159 RGLLEDVQEGRTTVPQLLASVQRWVQETKLL-AQARVMVPGPRGEVPAVWLLDAGIITQE 1217
L+ D Q GR T +++ + +++T+++ Q R + A L +A II+ E
Sbjct: 3588 AQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLE 3647
Query: 1218 TLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQ 1277
T L +GT+S + E + L+GTG VAGV L S SI QA++ GLL + +
Sbjct: 3648 TYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVAR 3707
Query: 1278 RLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLS 1337
LLEAQ A+GFL+DP+ +RL+V++AV+ GLVG EL ++L AERA GY DPY+ ++S
Sbjct: 3708 LLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTIS 3767
Query: 1338 LWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVD 1397
L+QAM+K L+P E L LL QLATGG+VDP G HLP A + G L+ T L+
Sbjct: 3768 LFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSE-P 3826
Query: 1398 KDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPV 1457
+ + + DPS ++++Y QL RC D TG LLLPL D + R ++ +
Sbjct: 3827 SEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPL--------SDARKLTFRGLRKQI 3878
Query: 1458 STGRFKGCSVSLWDLLLSEYVGADKRRELVALCR-SGRAAALRQVVSAVTALVEAAERQP 1516
+ V + E R L ++ + + S + + A ++
Sbjct: 3879 TMEELVRSQV------MDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKER 3932
Query: 1517 L---QATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSV-----KRSLE 1568
L QA +G+ + +A +L AQ + +D + TV+E M V + L
Sbjct: 3933 LSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLS 3992
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
+ G + + +S+ +A+++ ++ + LLEAQ ATG IIDP E+ +L VE A
Sbjct: 3993 AERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVA 4052
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL------- 1681
+K G+F +E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4053 YKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKR 4112
Query: 1682 EAQIATGG--------IIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNT 1733
E + ++ I+DP + V AYR G D +
Sbjct: 4113 ERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ-------------------- 4152
Query: 1734 HENLTYLQLLERCVEDPE------TGLYLLQIIKKGENYVY-INEATRHVLQSRTAKMRV 1786
TYL+L E+ E E G+ II + Y I++A L R+A +
Sbjct: 4153 ----TYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRSALDQY 4208
Query: 1787 GRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIK 1846
+ F D+LS R G+ S T ++ +
Sbjct: 4209 RAGTLSITEFADMLSG---NAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGP 4265
Query: 1847 VAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPS 1906
VA I T +V + +H V GQ L LE C G+ PS
Sbjct: 4266 VAGILDTETL-----EKVSITEAMHRNLVDNITGQRL---------LEAQACTGGIIDPS 4311
Query: 1907 TREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRE 1966
T E + +A K L+ + AQ A DP T+ K+S +A+ G + E +
Sbjct: 4312 TGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQ 4371
Query: 1967 RLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEV 2009
R L+ + G +P T +PL +A+Q+ ++ A +L +V
Sbjct: 4372 RFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV 4414
Score = 970 bits (2508), Expect = 0.0
Identities = 547/1287 (42%), Positives = 810/1287 (62%), Gaps = 33/1287 (2%)
Query: 1155 EEQRRGLL---EDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDA 1211
EEQ R L E+V + + L + + + A+ G R +V A L +A
Sbjct: 2588 EEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEA 2647
Query: 1212 GIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLL 1271
GI++ E L+ LAQG + ++A + V+ L G +AG+LL+ + K S+ A++ LL
Sbjct: 2648 GILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLL 2707
Query: 1272 PTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPY 1331
G LLEAQ ASGFL+DP+ N+RL+V +AVK G+VG EL +L AERA GY DPY
Sbjct: 2708 SPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPY 2767
Query: 1332 SRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQ 1391
+ +SL+QAM+KGL+ + G+ LL+ Q+ATGGV+DPVH +P A R G D + ++
Sbjct: 2768 TGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNR 2827
Query: 1392 VLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDT-----VLEVDDHT 1446
VL D K FFDP+ + +TY QL ERCV D ETGL LLPL ++ D
Sbjct: 2828 VLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEA 2887
Query: 1447 AVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVT 1506
V G+F+G +V++W+++ SEY A++RR+L+ R+GR + +++ +
Sbjct: 2888 RDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRIT-VEKIIKIII 2946
Query: 1507 ALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRS 1566
+VE E++ + F GLR V A +L +++I R+ +L +G +V++VAE+D+V+R+
Sbjct: 2947 TVVEEQEQKG-RLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 3005
Query: 1567 LEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVE 1626
L G N IAGV ++ +++SI AL++ +L A+ LLEAQA TG IIDPA + +LTV+
Sbjct: 3006 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVD 3065
Query: 1627 EAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIA 1686
EA +AG+ G E + KLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++
Sbjct: 3066 EAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLS 3125
Query: 1687 TGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERC 1746
TGGI+DP SHRVP+DVA G DEE +R L+ P D K + DP+T E TY +L +RC
Sbjct: 3126 TGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRC 3185
Query: 1747 VEDPETGLYLLQIIKKG----ENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSS 1802
D TGL LL + +K + +Y R + ++ VG F + V+ W+L+SS
Sbjct: 3186 RPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3245
Query: 1803 PYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQG-IKVAAIRGEVTAADLFN 1861
YFT ++++EL++++ +EK+++I+ T +EE ET Q + + +R V A++L
Sbjct: 3246 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3305
Query: 1862 SRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKEL 1921
S V+ + L+ G+T + LS L V+ L+GS C+AG+ + T+E +S++EA R+ L
Sbjct: 3306 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3365
Query: 1922 IPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDP 1981
+ A A LLEAQAATGFL+DP Q+L V EAV G+V EL E+LL AE+A TGYRDP
Sbjct: 3366 LRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDP 3425
Query: 1982 ATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIY 2041
+G TI LFQAMQK L+ + +RLLE Q+ATGG+IDP H HR+P++ AY+RG +++
Sbjct: 3426 YSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMN 3485
Query: 2042 ALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSE-------H 2094
+++D K F DPNT E ++YR+L ERC +TG L P+ K A +E +
Sbjct: 3486 RVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL-KGAEKAEVVETTQVY 3544
Query: 2095 IDDETRRALEAEQVEITVGRFRGQKP-TLWALLNSEYVTEEKKLQLVRMYRTHTRRALQT 2153
++ETRRA E Q++I G G +LW ++ S+ + EE++ QL+ ++ R +
Sbjct: 3545 TEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAG-RVTKER 3603
Query: 2154 VAQLILELIEKQETSNKH--LWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELM 2211
+ +I+E+IEK E + + +RR++TA +L + II+ E L G + +E +
Sbjct: 3604 MIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREAL 3663
Query: 2212 EDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGF 2271
E + YL GT +AGV +P G ++ +SIYQA+ KG+L A +LLEAQAATGF
Sbjct: 3664 EAESAWCYLYGTGSVAGVYLP-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGF 3718
Query: 2272 VIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIV 2331
++DPV+ RL+V+E V G+VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3719 LLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIP 3778
Query: 2332 REHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNT 2391
E +RLL+AQ+ATGG++DP +P++VAY+RGY +++ + L++PS + + + DP+T
Sbjct: 3779 TEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPST 3837
Query: 2392 HENLTYVQLLRRCVPDPDTGLYMLQLA 2418
E L+Y QLLRRC D TG +L L+
Sbjct: 3838 DERLSYTQLLRRCRRDDGTGQLLLPLS 3864
Score = 881 bits (2277), Expect = 0.0
Identities = 629/1746 (36%), Positives = 913/1746 (52%), Gaps = 133/1746 (7%)
Query: 41 RSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQ 100
R++ G +GQ S++ AM++GL+ G LLEAQ ATGG++D +PV A +
Sbjct: 2758 RAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR 2817
Query: 101 QGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEV--QLATG 158
+G E+ L T G+ DP E L Q + + V D G L + + A G
Sbjct: 2818 RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKG 2877
Query: 159 GLV----DPAQGVLVAPEPACHQGLLDRET---WHKLSELEPGTGDLR--FLNPNTLERL 209
G + A+ V + G +T W ++ E T + R L R+
Sbjct: 2878 GELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINS-EYFTAEQRRDLLRQFRTGRI 2936
Query: 210 TYHQLLERCVRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAV 269
T ++++ + ++ F + V AAELLE ++D + Q L+ G +
Sbjct: 2937 TVEKIIKIIITVVEEQEQ--KGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVR 2994
Query: 270 DVSARAEVRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLV 329
DV+ VRR L G +AGV L G K S + A + LLP A+ LLEAQA T ++
Sbjct: 2995 DVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHII 3054
Query: 330 DPITGQRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRP 389
DP T RL VDEAVRAGLV PE HE+LL AE+AVTG+ DP++G + LFQA+KKGL+ R
Sbjct: 3055 DPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPRE 3114
Query: 390 LALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLS----QAGSFSDGTHGG 445
LRLLDAQL+TGG+V P++ R+PL+ A GCLDE+T R LS A ++SD + G
Sbjct: 3115 QGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGE 3174
Query: 446 -LRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFR 504
Y +L C D TGL+ LPLS Q + + R+ V VG F+
Sbjct: 3175 PATYGELQQRCRPDQLTGLSLLPLSEKAARAR-QEELYSELQARETFEKTPVEVPVGGFK 3233
Query: 505 GRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAELSATLEQAAATA--RVTFSG 562
GR V++WEL+ SE ++EQR L +Q++ G ++VEK+ L +E+ R++FSG
Sbjct: 3234 GRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSG 3293
Query: 563 LRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQE 622
LR V ELL + ++ + +E+L+ G+ T KD+ L S + LQG+GC+AG+ L ++E
Sbjct: 3294 LRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKE 3353
Query: 623 RLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLL 682
++SIYEA +GLLR TA +LLEAQAATGF++DP N+ V EA++A V+GP++ +LL
Sbjct: 3354 KVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLL 3413
Query: 683 SAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDV 742
SAE+AVTGY DPY+G ISLFQAMQKGL++R+HGIRLLEAQIATGG+IDPVHSHRVPVDV
Sbjct: 3414 SAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3473
Query: 743 AYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQ 802
AY+RGYF + +N +L DPSDDTKGFFDPNTHENLTY QLLERCV DPETGL LLPL +
Sbjct: 3474 AYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAE 3533
Query: 803 SPLV--------DSATQQAFQNLLLSVK-YGRFQGQRVSAWELINSEYFSEGRRRQLLRR 853
V + T++AF+ + + G G +S WE++ S+ E +R QL+
Sbjct: 3534 KAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMAD 3593
Query: 854 YRQREVTLGQVAKLL-----EAETQRQADI-MLPALRSRVTVHQLLEAGIIDQQLLDQVL 907
++ VT ++ ++ + E RQ + +R R+T L EA II + + +
Sbjct: 3594 FQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLR 3653
Query: 908 AGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQ 967
GT S L + YL G G+V GV L S Q LS+YQA+++ LL VA LLEAQ
Sbjct: 3654 EGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQ 3713
Query: 968 AATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMK 1027
AATG ++DP E L+VDEAVR+G+VGPEL+ RL AE A+ G+RDP++ + +S+FQAMK
Sbjct: 3714 AATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMK 3773
Query: 1028 KGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSE--TFP 1085
K LIP E+A RLL+AQ+ATGGI+DP HLP+ VA QRGY++++ LS SE ++
Sbjct: 3774 KELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYV 3833
Query: 1086 TPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGTSLW 1145
P R SY QLL C RD+ +G LLPL ++ R L G + ++
Sbjct: 3834 DPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDA-----------RKL-TFRGLRKQITME 3881
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+ S E L +EG T++ ++ ++Q++++ T + A V V + +
Sbjct: 3882 ELVRSQVMDEATALQL----REGLTSIEEVTKNLQKFLEGTSCI--AGVFVDATKERLSV 3935
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAE---------QPAVKACLWG----------TG 1246
+ GII T L + + V + + AV+ + G
Sbjct: 3936 YQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAER 3995
Query: 1247 CVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKV 1306
V G SG S+ QA++ GL+ G RLLEAQ+A+G ++DP + RL VE A K
Sbjct: 3996 AVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKR 4055
Query: 1307 GLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLL---------- 1356
GL E++E L G+ DP + +L+ Q ME+ + GL LL
Sbjct: 4056 GLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERK 4115
Query: 1357 -----QVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQ 1411
V+ +VDP G + A R GL+D QT L+ + + ++
Sbjct: 4116 TSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECE---------WEE 4166
Query: 1412 VTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLW- 1470
+T D +++ S ++DD A L + +++ ++S+
Sbjct: 4167 ITISS------SDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRS---ALDQYRAGTLSITE 4217
Query: 1471 --DLLLSEYVGADKRRELVALCRS---GRAAALRQVVS---------AVTALVEAAERQP 1516
D+L G R V S A + Q+ S V +++ +
Sbjct: 4218 FADMLSGNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEK 4277
Query: 1517 L---QATFRGLRKQVSARDLFRAQ-----LISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
+ +A R L ++ + L AQ +I T + K + + V R
Sbjct: 4278 VSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINL 4337
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G T+ +MS +AL++ L LE Q TG +I+P ++ ++EA
Sbjct: 4338 AQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEA 4397
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-AT 1687
+ G T KL T P T +IS A+ + ++ G+RLLEA +T
Sbjct: 4398 LQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4457
Query: 1688 GGIIDP 1693
G P
Sbjct: 4458 KGYYSP 4463
Score = 869 bits (2246), Expect = 0.0
Identities = 711/2089 (34%), Positives = 1014/2089 (48%), Gaps = 390/2089 (18%)
Query: 2610 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 2665
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2520 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2579
Query: 2666 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 2712
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2580 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2636
Query: 2713 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 2772
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2637 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2693
Query: 2773 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 2832
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2694 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2751
Query: 2833 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2892
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2752 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2811
Query: 2893 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL- 2951
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L
Sbjct: 2812 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2871
Query: 2952 --AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRY 3009
A +G + E R A V+ G QG++V++WE++ + ++R+DLL ++
Sbjct: 2872 DKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQF 2931
Query: 3010 RAGTLTVEELGATLTSLLAQAQAQAR----------AEAEAGSPRPDPREALR------- 3052
R G +TVE++ + +++ + + + R AE R RE +
Sbjct: 2932 RTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGER 2991
Query: 3053 ----AATMEVKVGRLRGRAV--PVWDVLASGYVS--GAAREELL----------AEFGSG 3094
A ++ LRG V VW A +S A +++LL A+ G+G
Sbjct: 2992 SVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTG 3051
Query: 3095 TLDLPALTRRLTAIIEEAEEAPGARPQL--------------QDAWRG------------ 3128
+ PA + RLT ++EA A P+ +D + G
Sbjct: 3052 HIIDPATSARLT--VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKG 3109
Query: 3129 --PREPG-------PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQ 3168
PRE G + G D +S R G + ET A +A A A
Sbjct: 3110 LIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSD 3169
Query: 3169 EQTLRDATM-EVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLT 3227
T AT E+Q+ + + + S + AR++EL ++ A
Sbjct: 3170 PSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------R 3217
Query: 3228 RVIEETEERLSKVSFRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV----- 3278
E+T + F+G R V+ EL +S E LR G T+++V
Sbjct: 3218 ETFEKTPVEVPVGGFKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILI 3275
Query: 3279 TEMDSVKRYLEGTSCIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALV 3329
T ++ V+ + +G+ VPA + + E++ + K + G+
Sbjct: 3276 TIVEEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRT 3335
Query: 3330 LLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP-------- 3381
LL+ + ++S+ EA+ G++ LL A+ A DP
Sbjct: 3336 LLQGSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYV 3395
Query: 3382 ------------------------------YTGQQISLFQAMQKDLIVREHGIRLLEAQI 3411
Y+G ISLFQAMQK L++R+HGIRLLEAQI
Sbjct: 3396 HEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQI 3455
Query: 3412 ATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRR 3471
ATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL R
Sbjct: 3456 ATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLER 3515
Query: 3472 CVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWE 3524
CV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+WE
Sbjct: 3516 CVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWE 3575
Query: 3525 LLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA 3572
++ + E++R L++ ++AG +T E + + ++ + + + R A
Sbjct: 3576 VMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTA 3635
Query: 3573 ----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDV 3607
EA + LR T ++ G + G +P ++
Sbjct: 3636 EDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQA 3695
Query: 3608 LASGYVSG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREP 3666
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3696 LKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER- 3752
Query: 3667 GPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVW 3726
A G D Q + +E A R + L + R F P+ V
Sbjct: 3753 --AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV- 3808
Query: 3727 DVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------- 3772
YL++ D+ L + V + V T+ERLS
Sbjct: 3809 -AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGT 3856
Query: 3773 -----------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 3821
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++
Sbjct: 3857 GQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKF 3914
Query: 3822 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 3881
LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L
Sbjct: 3915 LEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGL 3969
Query: 3882 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 3941
+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLL
Sbjct: 3970 KLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLL 4029
Query: 3942 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQ 4001
EAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+Q
Sbjct: 4030 EAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQ 4089
Query: 4002 LLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLF 4061
L+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4090 LMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYEA-- 4143
Query: 4062 YREVSEDRRQDL-LSRYRA--STLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREA 4118
YR+ D + L LS +T+ + S++
Sbjct: 4144 YRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMI----------------------- 4180
Query: 4119 LRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIE 4178
+ R GR + D +A + R+A L ++ +GTL + L+
Sbjct: 4181 ---------IDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS---- 4223
Query: 4179 EAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ 4238
G++G + G + + A +R Q
Sbjct: 4224 -----------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLA 4254
Query: 4239 TLRDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDL 4290
+ D T E G G VS+ + + + + LL AQ G +
Sbjct: 4255 SWSDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI----- 4307
Query: 4291 VAVLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTL 4343
+ T ER ++ +GL ++ ++ + G P T ++
Sbjct: 4308 ------IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4361
Query: 4344 QEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQA 4403
+ ++ +R+LE G++ P D PGR + + +A+ +G + TA L + A
Sbjct: 4362 KGWLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGA 4416
Query: 4404 ATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 4451
+ ++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4417 YSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4465
Score = 852 bits (2202), Expect = 0.0
Identities = 715/2192 (32%), Positives = 1042/2192 (47%), Gaps = 408/2192 (18%)
Query: 1960 VNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEAL----RLLEVQVATGG 2015
+ +E + LK+E T ++ +T QA+Q+ + + ++L R +E + A
Sbjct: 2448 LQQEAKLLQLKSEEMQTVQQEQLLQET----QALQQSFLSEKDSLLQRERFIEQEKAKLE 2503
Query: 2016 VI---DPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERC 2072
+ + +L E ++ + ++ L++ + R+R + + ELQ+
Sbjct: 2504 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2563
Query: 2073 RPQEDTGWVLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVT 2132
+ + +L N+ R+ + +E RA A E+T + K
Sbjct: 2564 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL----------- 2612
Query: 2133 EEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSAII 2192
+ R AL A E +H F G+RR+++A L + I+
Sbjct: 2613 ------------PNGRDALDGPA---------AEAEPEHS-FDGLRRKVSAQRLQEAGIL 2650
Query: 2193 TEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKG 2252
+ E LQ L G +T EL + V+ YL+G S IAG+L+ A + EK+S+Y A+ +
Sbjct: 2651 SAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN-----EKLSVYAALQRQ 2705
Query: 2253 VLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTD 2312
+L PGTAL+LLEAQAA+GF++DPVRN RL+V E V GVVG E+ KLLSAERAVTGY D
Sbjct: 2706 LLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKD 2765
Query: 2313 PYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2372
PYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM
Sbjct: 2766 PYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2825
Query: 2373 NRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL---AGRGSAVHQLSE 2429
NRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L A +G +
Sbjct: 2826 NRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDS 2885
Query: 2430 ELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATL 2489
E R A V+ G QG++V++WE++ + ++R+DLL ++R G +TVE++ +
Sbjct: 2886 EARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKII 2945
Query: 2490 TSLLAQAQAQAR----------AEAEAGSPRPDPREALR-----------AATMEVKVGR 2528
+++ + + + R AE R RE + A ++
Sbjct: 2946 ITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 3005
Query: 2529 LRGRAV--PVWDVLASGYVS--RAAREELL----------AEFGSGTLDLPALTRRLTAI 2574
LRG V VW A +S A +++LL A+ G+G + PA + RLT
Sbjct: 3006 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLT-- 3063
Query: 2575 IEEAEEAPGARPQ--------------------------LQDARRG--PREPG------- 2599
++EA A P+ Q ++G PRE G
Sbjct: 3064 VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQ 3123
Query: 2600 PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQEQTLRDATM-EVQR 2647
+ G D +S R G + ET A +A A A T AT E+Q+
Sbjct: 3124 LSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQ 3183
Query: 2648 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVS 2707
+ + + S + AR++EL ++ A E+T +
Sbjct: 3184 RCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------RETFEKTPVEVPVGG 3231
Query: 2708 FRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV-----TEMDSVKRYLEGTS 2758
F+G R V+ EL +S E LR G T+++V T ++ V+ +
Sbjct: 3232 FKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERL 3289
Query: 2759 CIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDP 2809
+G+ VPA + + E++ + K + G+ LL+ +
Sbjct: 3290 SFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLE 3349
Query: 2810 VRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP---------------------- 2847
++S+ EA+ G++ LL A+ A DP
Sbjct: 3350 DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELH 3409
Query: 2848 ----------------YTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRV 2891
Y+G ISLFQAMQK L++R+HGIRLLEAQIATGG+IDPVHSHRV
Sbjct: 3410 EQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRV 3469
Query: 2892 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL 2951
PVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+TGL +L L
Sbjct: 3470 PVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL 3529
Query: 2952 AGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYREVSEDRRQD 3004
G A EE R A + ++ PG G+ G ++S+WE++ + E++R
Sbjct: 3530 KGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQ 3589
Query: 3005 LLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EAGSPRPDPR 3048
L++ ++AG +T E + + ++ + + + R A EA +
Sbjct: 3590 LMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETY 3649
Query: 3049 EALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYVSG-AAREE 3086
LR T ++ G + G +P ++ L G +S AR
Sbjct: 3650 NLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLL 3709
Query: 3087 LLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQ 3146
L A+ +G L P RLT ++EA P+L D A G D Q
Sbjct: 3710 LEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTGYRDPYTEQ 3764
Query: 3147 REGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRD 3206
+ +E A R + L + R F P+ V YL++ D
Sbjct: 3765 TISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRGYLNKDTHD 3821
Query: 3207 ELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------------KVS 3241
+ L + V + V T+ERLS K++
Sbjct: 3822 Q-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT 3870
Query: 3242 FRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPA 3301
FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSCIAGV V A
Sbjct: 3871 FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSCIAGVFVDA 3928
Query: 3302 KDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVG 3361
+E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEEAV G+VG
Sbjct: 3929 -----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVG 3983
Query: 3362 GEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVH 3421
E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIATGG+IDP
Sbjct: 3984 PEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEE 4043
Query: 3422 SHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLY 3481
SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+QL+ RC+ DP TGL
Sbjct: 4044 SHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLC 4103
Query: 3482 MLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLS 3541
+L L + S+ R V P + G+ +SV+E
Sbjct: 4104 LLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE----------------- 4142
Query: 3542 RYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRA 3601
YR G + + T L Q E S + + R GR
Sbjct: 4143 AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------DGVVKSMIIDRRSGRQ 4188
Query: 3602 VPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWR 3661
+ D +A + +A L ++ +GTL + L+
Sbjct: 4189 YDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS--------------------- 4223
Query: 3662 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG- 3720
G++G + G + + A +R Q + D T E G G
Sbjct: 4224 ------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEET--GPVAGI 4269
Query: 3721 ------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVAVLTRVIEETEER--L 3771
VS+ + + + + LL AQ G + + T ER +
Sbjct: 4270 LDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI-----------IDPSTGERFPV 4318
Query: 3772 SKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTS 3826
+ +GL ++ ++ + G P T ++ + ++ +R+LE
Sbjct: 4319 TDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQY 4378
Query: 3827 CIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVE 3886
G++ P D PGR + + +A+ +G + TA L + A + ++ P L++S +
Sbjct: 4379 LTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYK 4433
Query: 3887 EAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3917
+A+ +V +LL +A ++ GY PY+
Sbjct: 4434 DALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4465
Score = 727 bits (1876), Expect = 0.0
Identities = 710/2292 (30%), Positives = 1038/2292 (45%), Gaps = 316/2292 (13%)
Query: 3017 EELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLAS 3076
EE+ A S A +A E E G R + + LR+ + ++ R R + +
Sbjct: 1911 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE-QAELEAARQRQLAAEEERRR 1969
Query: 3077 GYVSGAAREELLAEFGSGTLDLPAL--TRRLTAIIEEAE------EAPGARPQLQDAWRG 3128
++ L AE + AL RL A +EEA E AR QLQ A
Sbjct: 1970 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEA 2028
Query: 3129 PREPGPAGRGDGDSGRSQREGQGEGETQEAAAA-------AAAARRQEQTLRDATMEVQR 3181
++ A Q+E + + Q+ + A AARR + +A ++ +R
Sbjct: 2029 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2088
Query: 3182 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAV-LTRVIEETEERLSKV 3240
Q R + EA R + A+ A A A L + E+ R ++
Sbjct: 2089 EAAQSR----------RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2138
Query: 3241 SFRGLR-RQVSASELHTSGILGPETLRDLAQGTKTLQ----EVTEMDSVKRYL-EGTSCI 3294
LR +Q + +E+ +TLR AQ + L ++ E D K L E +
Sbjct: 2139 EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRL 2198
Query: 3295 AGVLVPAKDQPGRQEK--------MSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 3346
A Q + E+ M + + AL+L + F+ +
Sbjct: 2199 KAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEK 2258
Query: 3347 LRLSVEEAVAAGVVGGE----------------------IQEKLLSAERAVTGYTDPYTG 3384
++ EEA V E ++EK+ + + A +
Sbjct: 2259 MKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2318
Query: 3385 QQ---ISLFQA---------MQKDLIVREHGI-RLLEA----QIATGGVIDPVHSHRVPV 3427
QQ ++ QA M + L G R LEA Q+ + + +
Sbjct: 2319 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2378
Query: 3428 DVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLL--RRCVPDPDTGLYMLQL 3485
A R D + R A+ + + T E +T VQ L +R D D +
Sbjct: 2379 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI 2438
Query: 3486 AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRA 3545
A +L +E + L + Q Q + + L +SE + LL R R
Sbjct: 2439 AELEREKEKLQQEAK--LLQLKSEEMQTVQQEQLLQETQALQQSFLSE--KDSLLQRERF 2494
Query: 3546 GTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPV- 3604
+L +A+AQ Q R E + + + A+ME R V
Sbjct: 2495 IEQEKAKLEQLFQDEVAKAQ-QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2553
Query: 3605 --WDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRG 3662
+ L +EELLAE + L +L + E+ A ++ +
Sbjct: 2554 RKQEELQQLEQQRRQQEELLAE------ENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2607
Query: 3663 PREPGPAGRG--DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG 3720
+ P GR DG + ++ E +G ++ +A R QE + A E+QR QG
Sbjct: 2608 ATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ----RLQEAGILSAE-ELQR-LAQG 2661
Query: 3721 RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 3780
+ E R E + + G + L+ ++ T E+LS + L+
Sbjct: 2662 HTT----------VDELARREDVRHYLQGRSSIAGLL------LKATNEKLSV--YAALQ 2703
Query: 3781 RQVSA---------SELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 3831
RQ+ + ++ + +L P R L + V + + L + G
Sbjct: 2704 RQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGY 2763
Query: 3832 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 3891
P Q ++S++QAM KG++ + LLEAQ ATG VIDPV + R+ V+ A
Sbjct: 2764 KDPYTGQ-----QISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRR 2818
Query: 3892 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEA--QIATGG 3949
G E+ L G+ DP T + ++ Q +++ + E G+ LL + A GG
Sbjct: 2819 GYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGG 2878
Query: 3950 VI--------DPVHSHRVPVDVAYRRG------------YFDEEMNRVLADPSDDTKGFF 3989
+ D V +G YF E R L +
Sbjct: 2879 ELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITV 2938
Query: 3990 DPNTHENLTYVQL-----------LRRCVPDP--------DTGLYMLQLAGRGSAVHQLS 4030
+ +T V+ LR VP D LY QL +V ++
Sbjct: 2939 EKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQ-QLQRGERSVRDVA 2997
Query: 4031 E--ELRCALRDARVTPGSGALQ-GQSVSVWELLFYREVSEDRRQDLLSRYRASTLTVEEL 4087
E +R ALR A V G + GQ +S++ L ++DLL A L +
Sbjct: 2998 EVDTVRRALRGANVIAGVWLEEAGQKLSIYNAL---------KKDLLPSDMAVALLEAQA 3048
Query: 4088 GAT-LTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGR--LRGRAVPVWDVLAS 4144
G + A+ AG P+ E L +A V R G++V ++ L
Sbjct: 3049 GTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKK 3108
Query: 4145 GYVSRAAREELL-AEFGSGTLDLPALTRRLTAII--------EEAEEAPGARPQLQDAWR 4195
G + R LL A+ +G + P+ + R+ + EE A A A+
Sbjct: 3109 GLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYS 3168
Query: 4196 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ---------TLRDATME 4246
P PA G+ + R Q G + + AA RQE+ T +E
Sbjct: 3169 DPSTGEPATYGELQ--QRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVE 3226
Query: 4247 VQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEE-RL 4305
V G F+GR V+VW+++ S Y + +R ELL Q G + + ++ +L ++EE E R
Sbjct: 3227 VPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQ 3286
Query: 4306 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 4365
++SF GLR V ASEL SG+L L G T+++++E+ SV+ L+G+ C+AG+
Sbjct: 3287 ERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGI 3346
Query: 4366 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 4425
+ +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL V EAV A
Sbjct: 3347 YLE-----DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKA 3401
Query: 4426 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 4485
GVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATGG+I
Sbjct: 3402 GVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGII 3461
Query: 4486 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 4545
DPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+
Sbjct: 3462 DPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPE 3521
Query: 4546 TGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYRE 4598
TGL +L L G A EE R A + ++ PG G+ G ++S+WE++
Sbjct: 3522 TGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDL 3581
Query: 4599 VSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EA 4642
+ E++R L++ ++AG +T E + + ++ + + + R A EA
Sbjct: 3582 IPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEA 3641
Query: 4643 GSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYV 4681
+ LR T ++ G + G +P ++ L G +
Sbjct: 3642 RIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLL 3701
Query: 4682 SG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRG 4740
S AR L A+ +G L P RLT ++EA P+L D A G
Sbjct: 3702 SAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTG 3756
Query: 4741 DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSS 4800
D Q + +E A R + L + R F P+ V
Sbjct: 3757 YRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRG 3813
Query: 4801 YLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------- 4840
YL++ D+ L + V + V T+ERLS
Sbjct: 3814 YLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLP 3862
Query: 4841 -----KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSC 4895
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSC
Sbjct: 3863 LSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSC 3920
Query: 4896 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 4955
IAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEE
Sbjct: 3921 IAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 3975
Query: 4956 AVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 5015
AV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIAT
Sbjct: 3976 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4035
Query: 5016 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRAT 5075
GG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTYLQL++R
Sbjct: 4036 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4095
Query: 5076 LDPETGLLFLSL 5087
DP+TGL L L
Sbjct: 4096 TDPQTGLCLLPL 4107
Score = 619 bits (1597), Expect = e-176
Identities = 476/1531 (31%), Positives = 736/1531 (48%), Gaps = 227/1531 (14%)
Query: 40 ARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKAL 99
A IAGV++E +GQ S+Y A+++ LLP+ + ALLEAQA TG ++D A L V +A+
Sbjct: 3009 ANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEAV 3068
Query: 100 QQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGG 159
+ GLVG E EKLL+AE+A TGY DPY G+ ++LFQA+ K ++ R G L+ QL+TGG
Sbjct: 3069 RAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTGG 3128
Query: 160 LVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCV 219
+VDP++ V + AC +G LD ET LS P + +P+T E TY +L +RC
Sbjct: 3129 IVDPSKSHRVPLDVACARGCLDEETSRALS--APRADAKAYSDPSTGEPATYGELQQRCR 3186
Query: 220 RAPGSGLALLPL------------------KITFRS----------MGGAVSAAELLEVG 251
+GL+LLPL + TF G V+ EL+
Sbjct: 3187 PDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISSE 3246
Query: 252 ILD-EQAVQGLREGRLAAV--------------DVSARAEVRRYLEGTGS--------VA 288
EQ + LR+ R V +V + R G + +
Sbjct: 3247 YFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLAS 3306
Query: 289 GVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAG-- 346
GV+ + + + + L +G+ LL+ + T +++ + EA+R G
Sbjct: 3307 GVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGLL 3366
Query: 347 -----------------LVSPELHEQLLVAE-------------------QAVTGHHDPF 370
LV P +++L V E +AVTG+ DP+
Sbjct: 3367 RATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDPY 3426
Query: 371 SGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQR 430
SGS I LFQAM+KGLV R +RLL+AQ+ATGG++ P R+P++ A + G E+ R
Sbjct: 3427 SGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMNR 3486
Query: 431 QLSQ-----AGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPP-FIK 484
L+ G F TH L Y QLL CV DPETGL LPL G + + + +
Sbjct: 3487 VLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVETTQVYTE 3546
Query: 485 YSTRQALSTATATV-SVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAA 543
TR+A + G G +SLWE++ S+ I EQRA L +Q G ++ E++
Sbjct: 3547 EETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMII 3606
Query: 544 ELSATLEQAAATAR---VTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLA 600
+ +E+ + ++ +R +T +L +A II + Y L G + ++
Sbjct: 3607 IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAE 3666
Query: 601 SAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANK 660
SA YL GTG +AG+ LPGS++ LSIY+A KGLL A +LLEAQAATGF++DP +
Sbjct: 3667 SAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGE 3726
Query: 661 GHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLL 720
+V+EA+R ++GP++ +LLSAERAVTGY DPYT Q ISLFQAM+K LI E +RLL
Sbjct: 3727 RLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLL 3786
Query: 721 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQ 780
+AQ+ATGG++DP +P++VAY+RGY ++ + L +PS + + + DP+T E L+Y Q
Sbjct: 3787 DAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQ 3845
Query: 781 LLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSE 840
LL RC RD TG LLPLS A + F+ L ++++ EL+ S+
Sbjct: 3846 LLRRCRRDDGTGQLLLPLS--------DARKLTFRGL----------RKQITMEELVRSQ 3887
Query: 841 YFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQ 900
E QL E + K LE T A + + A + R++V+Q ++ GII
Sbjct: 3888 VMDEATALQLREGLTSIEEVTKNLQKFLEG-TSCIAGVFVDATKERLSVYQAMKKGIIRP 3946
Query: 901 QLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVA 960
++L A G V G +L++ +A+R ++GP
Sbjct: 3947 GTAFELLEAQ-------------------AATGYVIDPIKGLKLTVEEAVRMGIVGPEFK 3987
Query: 961 LALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQV 1020
LL A+ A DP+S + +S+ +A+++G++ + RL A+ A G DP ++
Sbjct: 3988 DKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRL 4047
Query: 1021 SVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSS 1080
V A K+GL E L + T G DP + +L
Sbjct: 4048 PVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENL---------------------- 4085
Query: 1081 SETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPT--EEQVQRSLQAVPGA 1138
+Y QL+E C D +GL LLPL E T + V++ +
Sbjct: 4086 -------------TYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDP 4132
Query: 1139 KDGTSLWDLLSSCHFTEEQRRGLLE-----DVQEGRTTVPQLLASVQRWVQETKLLAQAR 1193
+ G + E R+GL++ ++ E ++ S V ++ ++ +
Sbjct: 4133 ETGKEM-------SVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRR- 4184
Query: 1194 VMVPGPRGEVPAVWLLDAGIITQETLEALAQGTQSPAQVAE------------------- 1234
G + ++ + +I + L+ GT S + A+
Sbjct: 4185 ---SGRQYDIDDA--IAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSS 4239
Query: 1235 -----QPAV---KACLWG-----TGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLE 1281
PAV + W TG VAG+L + K SI +A+ L+ GQRLLE
Sbjct: 4240 SSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLE 4299
Query: 1282 AQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQA 1341
AQ +G ++DP +R V DAV GLV + + +++ A++A G+ DP ++ +S QA
Sbjct: 4300 AQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQA 4359
Query: 1342 MEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNK 1401
++KG + G L+VQ TGG+++P +P A + G +D +T+Q L V +K
Sbjct: 4360 LKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSK 4419
Query: 1402 FFFDPSARDQVTYQQLRERCVCDSETGLLLL 1432
+ P + +++Y+ +R + + TGL LL
Sbjct: 4420 YLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4450
Score = 350 bits (897), Expect = 3e-95
Identities = 288/927 (31%), Positives = 451/927 (48%), Gaps = 110/927 (11%)
Query: 4243 ATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE 4302
AT+ G+FQG+ V++W+++ S Y + +R +LL Q G + + ++ ++ V+EE E
Sbjct: 2894 ATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE 2953
Query: 4303 ERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCI 4362
++ ++ F GLR V A+EL S ++ E + L +G +++++V E+D+V+R L G + I
Sbjct: 2954 QK-GRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRALRGANVI 3012
Query: 4363 AGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEA 4422
AGV + Q K+SIY A+ K +L A+ LLEAQA TG +IDP + RL+V+EA
Sbjct: 3013 AGVWLEEAGQ-----KLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEA 3067
Query: 4423 VAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 4482
V AG+VG E EKLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++TG
Sbjct: 3068 VRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTG 3127
Query: 4483 GVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVP 4542
G++DP SHRVP+DVA RG DEE +R L+ P D K + DP+T E TY +L +RC P
Sbjct: 3128 GIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRCRP 3187
Query: 4543 DPDTGLYMLQLAGRGSAVHQLSEELRCALRDARV---TPGS---GALQGQSVSVWELLFY 4596
D TGL +L L+ + + Q EEL L+ TP G +G++V+VWEL+
Sbjct: 3188 DQLTGLSLLPLSEKAARARQ--EELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3245
Query: 4597 REVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAE-AGSPRPDPREAL-- 4653
+ ++RQ+LL ++R G +TVE++ L +++ + + + +G P P L
Sbjct: 3246 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3305
Query: 4654 -----RAATMEVKVGR---------------LRGRA-------------VPVWDVLASGY 4680
RA ++K G+ L+G V +++ + G
Sbjct: 3306 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3365
Query: 4681 VSGAAREELL-AEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGR 4739
+ LL A+ +G L P +RL + EA +A P+L + E G
Sbjct: 3366 LRATTAALLLEAQAATGFLVDPVRNQRL--YVHEAVKAGVVGPELHEQLLSA-EKAVTGY 3422
Query: 4740 GDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQF----QGRPVSVWD 4795
D SG + Q A ++ +R ++ G V V
Sbjct: 3423 RDPYSGSTISLFQ---------AMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3473
Query: 4796 VLFSSYLSEARRDELLAQHAAGALGLPD--------LVAVLTRVIEETEERLSKVSFRGL 4847
Y SE + +LA + G D +L R +E+ E L + +G
Sbjct: 3474 AYQRGYFSE-EMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGA 3532
Query: 4848 RRQ--VSASELHTSGILG---PETLRDLAQG------TKTLQEVTEMDSVK--------- 4887
+ V ++++T ET D+ G T +L EV + D +
Sbjct: 3533 EKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMA 3592
Query: 4888 -----RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFV 4942
R + I + + K + RQ+ ++ Y V R TA L EA+ +
Sbjct: 3593 DFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDY----VRRRLTAEDLFEARIISLET 3648
Query: 4943 IDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 5002
+ +R S+ EA+ A E L +V G P + Q +S++QA++K L+
Sbjct: 3649 YNLLREGTRSLREALEA-----ESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSA 3703
Query: 5003 EHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTH 5062
E LLEAQ ATG ++DPV R+ VD A R+G E++ L G+ DP T
Sbjct: 3704 EVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTE 3763
Query: 5063 ENLTYLQLLQRATLDPETGLLFLSLSL 5089
+ ++ Q +++ + E L L L
Sbjct: 3764 QTISLFQAMKKELIPTEEALRLLDAQL 3790
Score = 347 bits (889), Expect = 2e-94
Identities = 202/360 (56%), Positives = 242/360 (67%), Gaps = 25/360 (6%)
Query: 4746 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 4801
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2520 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2579
Query: 4802 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 4848
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2580 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2636
Query: 4849 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 4908
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2637 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2693
Query: 4909 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 4968
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2694 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2751
Query: 4969 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 5028
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2752 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2811
Query: 5029 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLS 5088
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLL+R DPETGL L L+
Sbjct: 2812 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2871
Score = 254 bits (648), Expect = 2e-66
Identities = 137/307 (44%), Positives = 206/307 (67%), Gaps = 8/307 (2%)
Query: 4784 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE--ERLSK 4841
G G +S+W+V+ S + E +R +L+A AG + ++ ++ +IE+TE +
Sbjct: 3564 GSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGL 3623
Query: 4842 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 4901
S+ +RR+++A +L + I+ ET L +GT++L+E E +S YL GT +AGV +
Sbjct: 3624 ASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYL 3683
Query: 4902 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 4961
P G ++ +SIYQA+ KG+L A +LLEAQAATGF++DPV+ RL+V+EAV G+
Sbjct: 3684 P-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGL 3738
Query: 4962 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 5021
VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI E +RLL+AQ+ATGG++DP
Sbjct: 3739 VGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDP 3798
Query: 5022 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETG 5081
+P++VAY+RGY +++ + L++PS + + + DP+T E L+Y QLL+R D TG
Sbjct: 3799 RLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQLLRRCRRDDGTG 3857
Query: 5082 LLFLSLS 5088
L L LS
Sbjct: 3858 QLLLPLS 3864
Score = 107 bits (267), Expect = 3e-22
Identities = 73/212 (34%), Positives = 111/212 (52%), Gaps = 5/212 (2%)
Query: 4347 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4406
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4251 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4305
Query: 4407 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 4466
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4306 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4365
Query: 4467 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 4526
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4366 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4425
Query: 4527 THENLTYVQLLRRCVPDPDTGLYMLQLAGRGS 4558
T ++Y L R + + TGL +L+ A + +
Sbjct: 4426 TKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4457
Score = 107 bits (266), Expect = 4e-22
Identities = 73/210 (34%), Positives = 109/210 (51%), Gaps = 5/210 (2%)
Query: 4881 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4940
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4251 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4305
Query: 4941 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 5000
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4306 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4365
Query: 5001 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 5060
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4366 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4425
Query: 5061 THENLTYLQLLQRATLDPETGLLFLSLSLQ 5090
T ++Y L R+ ++ TGL L + Q
Sbjct: 4426 TKLKISYKDALDRSMVEEGTGLRLLEAAAQ 4455
Score = 105 bits (261), Expect = 2e-21
Identities = 69/217 (31%), Positives = 114/217 (52%), Gaps = 3/217 (1%)
Query: 13 GTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQ 72
G++S+ S P L + + P + +AG+ + + S+ AM + L+ GQ
Sbjct: 4237 GSSSSYPIS-PAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQ 4295
Query: 73 ALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLA 132
LLEAQA TGG++D + G+ PV+ A+ +GLV + +++ A++A G+ DP K++
Sbjct: 4296 RLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMS 4355
Query: 133 LFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLLDRETWHKLSELE 192
QA+ K + GQ +LEVQ TGGL++P V + A +G +D T KL ++
Sbjct: 4356 AAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV- 4414
Query: 193 PGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALL 229
G P T +++Y L+R + G+GL LL
Sbjct: 4415 -GAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4450
Score = 70.5 bits (171), Expect = 4e-11
Identities = 61/227 (26%), Positives = 102/227 (44%), Gaps = 17/227 (7%)
Query: 4832 IEETEERLS--KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 4889
++ T+ERLS + +G+ R +A EL + + + T++E M V
Sbjct: 3926 VDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPE 3985
Query: 4890 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 4949
+ A V P + +S++QAM KG++ + LLEAQ ATG +IDP +
Sbjct: 3986 FKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESH 4045
Query: 4950 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 5009
RL VE A G+ E+ E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4046 RLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLL 4105
Query: 5010 -------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 5041
E + ++ ++DP + V AYR+G D +
Sbjct: 4106 PLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4152
Score = 60.8 bits (146), Expect = 3e-08
Identities = 32/119 (26%), Positives = 61/119 (51%)
Query: 4971 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 5030
L ++ G T +++S++ A+Q+ L+ + LLEAQ A+G ++DPV + R+ V+
Sbjct: 2678 LQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVN 2737
Query: 5031 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSL 5089
A + G E++ L G+ DP T + ++ Q +Q+ + E G+ L +
Sbjct: 2738 EAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQI 2796
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4254 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4310
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4186 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4241
Query: 4311 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4359
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4242 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4301
Query: 4360 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4386
+C G++ P+ + P + KMS QA+
Sbjct: 4302 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4361
Query: 4387 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4446
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4362 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4421
Query: 4447 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 4487
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4422 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4463
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4788 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4844
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4186 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4241
Query: 4845 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4893
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4242 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4301
Query: 4894 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4920
+C G++ P+ + P + KMS QA+
Sbjct: 4302 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4361
Query: 4921 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4980
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4362 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4421
Query: 4981 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 5021
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4422 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4463
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 1268 bits (3280), Expect = 0.0
Identities = 798/1967 (40%), Positives = 1134/1967 (57%), Gaps = 218/1967 (11%)
Query: 1511 AAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLEGG 1570
AAE +P + +F GLR++VSA+ L A ++S + L L+QG TTV E+A + V+ L+G
Sbjct: 2664 AAEAEP-EHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGR 2722
Query: 1571 NFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFK 1630
+ IAG+L++ T E++S+ AL+R +L PGTAL+LLEAQAA+GF++DP NR+LTV EA K
Sbjct: 2723 SSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVK 2782
Query: 1631 AGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGI 1690
G+ G E + KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGG+
Sbjct: 2783 EGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGV 2842
Query: 1691 IDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 1750
IDPVHSHRVPVDVAYR GYFDEEMNR+LADPSDDTKGFFDPNTHENLTYLQLLERCVEDP
Sbjct: 2843 IDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDP 2902
Query: 1751 ETGLYLLQI---IKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTE 1807
ETGL LL + KG VY + R V + T G+F + V+ W++++S YFT
Sbjct: 2903 ETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTA 2962
Query: 1808 DRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLFNSRVIDQ 1867
+++R+L++++ +EK+++II T +EE E Q + +R V AA+L SRVID+
Sbjct: 2963 EQRRDLLRQFRTGRITVEKIIKIIITVVEEQE-QKGRLCFEGLRSLVPAAELLESRVIDR 3021
Query: 1868 KTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFA 1927
+ L+ G + ++ ++ V+ L G++ IAGV + + +S++ A +K+L+P+ A
Sbjct: 3022 ELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMA 3081
Query: 1928 TWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTI 1987
LLEAQA TG ++DP T +L+VDEAV GLV E E+LL AE+A TGYRDP TG ++
Sbjct: 3082 VALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSV 3141
Query: 1988 PLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQ 2047
LFQA++K LI + + LRLL+ Q++TGG++DP HR+PL+ A RGCL ++ +S
Sbjct: 3142 SLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAP 3201
Query: 2048 KHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVN-KAAR---DSEHIDDETRRAL 2103
+ K + DP+T E +Y ELQ+RCRP + TG L P++ KAAR + + + + R
Sbjct: 3202 RADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETF 3261
Query: 2104 EAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIE 2163
E VE+ VG F+G+ T+W L++SEY T E++ +L+R +RT + ++ V ++++ ++E
Sbjct: 3262 EKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRT-GKVTVEKVIKILITIVE 3320
Query: 2164 KQET-SNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEG 2222
+ ET + L F G+R + ASELL+S +++ + L+ G++T ++L E V+ L+G
Sbjct: 3321 EVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQG 3380
Query: 2223 TSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLS 2282
+ C+AG+ + +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL
Sbjct: 3381 SGCLAGIYL-----EDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLY 3435
Query: 2283 VEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQ 2342
V E V AGVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQ
Sbjct: 3436 VHEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQ 3495
Query: 2343 IATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLR 2402
IATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL
Sbjct: 3496 IATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLE 3555
Query: 2403 RCVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVW 2455
RCV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+W
Sbjct: 3556 RCVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLW 3615
Query: 2456 ELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAE 2503
E++ + E++R L++ ++AG +T E + + ++ + + + R
Sbjct: 3616 EVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLT 3675
Query: 2504 A----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWD 2538
A EA + LR T ++ G + G +P ++
Sbjct: 3676 AEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQ 3735
Query: 2539 VLASGYVS-RAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDARRGPRE 2597
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3736 ALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER 3793
Query: 2598 PGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSV 2657
A G D Q + +E A R + L + R F P+ V
Sbjct: 3794 ---AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV 3849
Query: 2658 WDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS------------- 2704
YL++ D+ L + V + V T+ERLS
Sbjct: 3850 --AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDG 3896
Query: 2705 ------------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKR 2752
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ ++++
Sbjct: 3897 TGQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQK 3954
Query: 2753 YLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 2812
+LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++
Sbjct: 3955 FLEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKG 4009
Query: 2813 LRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRL 2872
L+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRL
Sbjct: 4010 LKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRL 4069
Query: 2873 LEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYV 2932
LEAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+
Sbjct: 4070 LEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYL 4129
Query: 2933 QLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELL 2992
QL+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4130 QLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE-- 4183
Query: 2993 FYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALR 3052
YR G + + T L Q E S
Sbjct: 4184 ---------------AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------D 4214
Query: 3053 AATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEA 3112
+ + R GR + D +A + +A L ++ +GTL + L+
Sbjct: 4215 GVVKSMIIDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS------ 4264
Query: 3113 EEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTL 3172
G++G + G + + A +R Q +
Sbjct: 4265 ---------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASW 4297
Query: 3173 RDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVA 3224
D T E G G VS+ + + + + LL AQ G +
Sbjct: 4298 SDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI------- 4348
Query: 3225 VLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQE 3277
+ T ER ++ +GL ++ ++ + G P T ++ +
Sbjct: 4349 ----IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKG 4404
Query: 3278 VTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 3337
++ +R+LE G++ P D PGR + + +A+ +G + TA L + A +
Sbjct: 4405 WLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYS 4459
Query: 3338 GFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3383
++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4460 KYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4506
Score = 1127 bits (2914), Expect = 0.0
Identities = 724/1911 (37%), Positives = 1065/1911 (55%), Gaps = 110/1911 (5%)
Query: 522 EQRAMLAQQYQEGTLSVEKL-AAELSAT---------LEQAAATARV--TFSGLRDTVTP 569
EQ +L +Q++ E++ A++++AT L+ AA A +F GLR V+
Sbjct: 2623 EQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSA 2682
Query: 570 GELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEA 629
L +A I+ + +RL G T ++ + YLQG IAGLLL + E+LS+Y A
Sbjct: 2683 QRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAA 2742
Query: 630 RCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVT 689
+ LL PGTALILLEAQAA+GF++DP N+ +V EA++ V+GP++ KLLSAERAVT
Sbjct: 2743 LQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVT 2802
Query: 690 GYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 749
GY DPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF
Sbjct: 2803 GYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 2862
Query: 750 DQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSP----- 804
D+ +N +L DPSDDTKGFFDPNTHENLTYLQLLERCV DPETGL LLPL+ +
Sbjct: 2863 DEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELV 2922
Query: 805 LVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQV 864
DS + F+ +S +G+FQG+ V+ WE+INSEYF+ +RR LLR++R +T+ ++
Sbjct: 2923 YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKI 2982
Query: 865 AKLLEA---ETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDG 921
K++ E +++ + LRS V +LLE+ +ID++L Q+ G S + +D
Sbjct: 2983 IKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDT 3042
Query: 922 VRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPES 981
VRR L G + GV L +GQ+LS+Y A+++ LL +A+ALLEAQA TG I+DP +
Sbjct: 3043 VRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSAR 3102
Query: 982 LSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLE 1041
L+VDEAVR G+VGPE + +L AE A+ G+RDP++G+ VS+FQA+KKGLIP EQ RLL+
Sbjct: 3103 LTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLD 3162
Query: 1042 AQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSS---SSETFPTPDGQGRTSYAQL 1098
AQ++TGGI+DP+ H +P+ VA RG +D+E ALS+ ++ + P +Y +L
Sbjct: 3163 AQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGEL 3222
Query: 1099 LEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQA------------VPGAKDGT-SLW 1145
+ C D+ +GL LLPL E A A +E++ LQA V G K T ++W
Sbjct: 3223 QQRCRPDQLTGLSLLPLSEKA-ARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVW 3281
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+SS +FT EQR+ LL + G+ TV +++ + V+E + L Q R+ G R VPA
Sbjct: 3282 ELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPA 3341
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQA 1265
LL +G++++ E L G + ++E +V+ L G+GC+AG+ L+ + K SI +A
Sbjct: 3342 SELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEA 3401
Query: 1266 VRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAA 1325
+R GLL LLEAQ A+GFLVDP+ NQRL V +AVK G+VG EL EQL AE+A
Sbjct: 3402 MRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVT 3461
Query: 1326 GYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLL 1385
GY DPYS +++SL+QAM+KGLV + G+ LL+ Q+ATGG++DPVH +P A + G
Sbjct: 3462 GYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYF 3521
Query: 1386 DTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDH 1445
+ ++VL D K FFDP+ + +TY+QL ERCV D ETGL LLPL EV +
Sbjct: 3522 SEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVET 3581
Query: 1446 TAV--------ALRAMKVPV-STGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAA 1496
T V A ++ + G G ++SLW+++ S+ + ++R +L+A ++GR
Sbjct: 3582 TQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVT 3641
Query: 1497 ALRQVVSAVTALVEAAE--RQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTV 1554
R ++ + ++E E RQ A++ +R++++A DLF A++IS +T + L +GT ++
Sbjct: 3642 KERMII-IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSL 3700
Query: 1555 KEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFI 1614
+E E +S L G +AGV + G+++ +SI +AL++ +L A +LLEAQAATGF+
Sbjct: 3701 REALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFL 3760
Query: 1615 IDPAENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 1674
+DP + +LTV+EA + G+ G E + +LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3761 LDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPT 3820
Query: 1675 EHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTH 1734
E +RLL+AQ+ATGGI+DP +P++VAY+ GY +++ + L++PS+ + + DP+T
Sbjct: 3821 EEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSE-VRSYVDPSTD 3879
Query: 1735 ENLTYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVV 1794
E L+Y QLL RC D TG LL + A+ R + +
Sbjct: 3880 ERLSYTQLLRRCRRDDGTGQLLLPL--------------------SDARKLTFRGLRKQI 3919
Query: 1795 SFWDLLSSPYFTED---RKRELIQEYGAQSGGLEKLLE-------IITTTIEETETQNQG 1844
+ +L+ S E + RE + + L+K LE + +E + Q
Sbjct: 3920 TMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQA 3979
Query: 1845 IKVAAIRG----EVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIA 1900
+K IR E+ A VID L V + E L +
Sbjct: 3980 MKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVT 4039
Query: 1901 GVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLV 1960
G P + +++SL +A +K LI LLEAQ ATG ++DP +L V+ A GL
Sbjct: 4040 GYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLF 4099
Query: 1961 NEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLL------------- 2007
+EE+ E L G+ DP T + + Q M++ + + L LL
Sbjct: 4100 DEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSS 4159
Query: 2008 --EVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSY 2065
V+ ++DP+ + + AYR+G + Y +S+Q+ + ++ V
Sbjct: 4160 KSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKS 4219
Query: 2066 RELQERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALE----AEQVEITVGRFRGQKPT 2121
+ R Q D + + K D +D L A+ + G FR + +
Sbjct: 4220 MIIDRRSGRQYD---IDDAIAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSS 4276
Query: 2122 LWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQI 2181
+ + + + QL + T L E +EK S + + I
Sbjct: 4277 VGSSSSYPISPAVSRTQLA-SWSDPTEETGPVAGILDTETLEK--VSITEAMHRNLVDNI 4333
Query: 2182 TASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQE 2241
T LL + T ++ R + + V + + +A + P +
Sbjct: 4334 TGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKT 4393
Query: 2242 KMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLL 2301
KMS QA+ KG L LE Q TG +I+P R+ ++E + G V + +KL
Sbjct: 4394 KMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLR 4453
Query: 2302 SAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 2351
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4454 DVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4504
Score = 1054 bits (2725), Expect = 0.0
Identities = 630/1557 (40%), Positives = 924/1557 (59%), Gaps = 83/1557 (5%)
Query: 869 EAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCG 928
EAE + D LR +V+ +L EAGI+ + L ++ G + + L + VR YL G
Sbjct: 2666 EAEPEHSFD----GLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQG 2721
Query: 929 LGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAV 988
++ G+ L + ++LS+Y A++++LL P AL LLEAQAA+G ++DP L+V+EAV
Sbjct: 2722 RSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAV 2781
Query: 989 RRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGG 1048
+ GVVGPEL+ +L AE A+ G++DP++G+Q+S+FQAM+KGLI E RLLEAQ+ATGG
Sbjct: 2782 KEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGG 2841
Query: 1049 IIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRD 1105
+IDP H +P+ VA +RGY D+EM L+ S+ F P+ +Y QLLE C D
Sbjct: 2842 VIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVED 2901
Query: 1106 ETSGLHLLPLPESAPA--------LPTEEQVQRSLQAVPGAK---DGTSLWDLLSSCHFT 1154
+GL LLPL + A + +++ + P K ++W++++S +FT
Sbjct: 2902 PETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFT 2961
Query: 1155 EEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDAGII 1214
EQRR LL + GR TV +++ + V+E + + R+ G R VPA LL++ +I
Sbjct: 2962 AEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE--QKGRLCFEGLRSLVPAAELLESRVI 3019
Query: 1215 TQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTG 1274
+E + L +G +S VAE V+ L G +AGV L+ +G K SI A++ LLP+
Sbjct: 3020 DRELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSD 3079
Query: 1275 LGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRA 1334
+ LLEAQ +G ++DP + RL+V++AV+ GLVG E E+L AE+A GY DPY+
Sbjct: 3080 MAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQ 3139
Query: 1335 SLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLT 1394
S+SL+QA++KGL+P+ +GL LL QL+TGG+VDP +P AC G LD +TS+ L+
Sbjct: 3140 SVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALS 3199
Query: 1395 AVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMK 1454
A D K + DPS + TY +L++RC D TGL LLPL + L+A +
Sbjct: 3200 APRADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARE 3259
Query: 1455 ------VPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVTAL 1508
V V G FKG +V++W+L+ SEY A++R+EL+ R+G+ + + +T +
Sbjct: 3260 TFEKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIV 3319
Query: 1509 VEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
E + + +F GLR V A +L + ++SR ++L G TTVK+++E+ SV+ L+
Sbjct: 3320 EEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQ 3379
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G +AG+ ++ T+E++SI EA+RR +LR TA +LLEAQAATGF++DP N++L V EA
Sbjct: 3380 GSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEA 3439
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 1688
KAG+ G E + +LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATG
Sbjct: 3440 VKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATG 3499
Query: 1689 GIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVE 1748
GIIDPVHSHRVPVDVAY+ GYF EEMNR+LADPSDDTKGFFDPNTHENLTY QLLERCVE
Sbjct: 3500 GIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVE 3559
Query: 1749 DPETGLYLLQI--IKKGE----NYVYINEATRHVLQSRTAKM-RVGRFADQVVSFWDLLS 1801
DPETGL LL + +K E VY E TR + + G +S W+++
Sbjct: 3560 DPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQ 3619
Query: 1802 SPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETE-TQNQGI-KVAAIRGEVTAADL 1859
S E+++ +L+ ++ A E+++ II IE+TE + QG+ +R +TA DL
Sbjct: 3620 SDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDL 3679
Query: 1860 FNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRK 1919
F +R+I +T + LR G + E YL G+ +AGV +P +R+ +S+++A +K
Sbjct: 3680 FEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKK 3739
Query: 1920 ELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYR 1979
L+ A A LLEAQAATGFLLDP ++L+VDEAV GLV EL +RLL AERA TGYR
Sbjct: 3740 GLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYR 3799
Query: 1980 DPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKD 2039
DP T TI LFQAM+K+LI EALRLL+ Q+ATGG++DP+ LPLE AY+RG L+KD
Sbjct: 3800 DPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKD 3859
Query: 2040 IYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDET 2099
+ +S+ +R +VDP+T E++SY +L RCR + TG +L P++ A + +
Sbjct: 3860 THDQLSEPSEVRS-YVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT------- 3911
Query: 2100 RRALEAEQVEITVGRFRG--QKPTLWALLNSEYVTEEKKLQL------VRMYRTHTRRAL 2151
FRG ++ T+ L+ S+ + E LQL + + ++ L
Sbjct: 3912 ---------------FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFL 3956
Query: 2152 QTVAQLILELIE--KQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQE 2209
+ + + ++ K+ S +GI R TA ELL + T ++ ++ + T +E
Sbjct: 3957 EGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 4016
Query: 2210 LMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 2269
+ V + A V P + +S++QAM KG++ + LLEAQ AT
Sbjct: 4017 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4076
Query: 2270 GFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDL 2329
G +IDP + RL VE G+ E+ E L G+ DP T + ++ Q M++ +
Sbjct: 4077 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4136
Query: 2330 IVREHGIRLL-------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 2371
+ G+ LL E + ++ ++DP + V AYR+G D +
Sbjct: 4137 TDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4193
Score = 999 bits (2583), Expect = 0.0
Identities = 666/1843 (36%), Positives = 989/1843 (53%), Gaps = 126/1843 (6%)
Query: 234 TFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLL 293
+F + VSA L E GIL + +Q L +G +++ R +VR YL+G S+AG++L
Sbjct: 2672 SFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLK 2731
Query: 294 PEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELH 353
K S + A LL GTAL LLEAQAA+ L+DP+ +RL V+EAV+ G+V PELH
Sbjct: 2732 ATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELH 2791
Query: 354 EQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRL 413
+LL AE+AVTG+ DP++G QI LFQAM+KGL+ R +RLL+AQ+ATGG++ P R+
Sbjct: 2792 HKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRV 2851
Query: 414 PLEAALRCGCLDEDTQRQLSQA-----GSFSDGTHGGLRYEQLLALCVTDPETGLAFLPL 468
P++ A R G DE+ R L+ G F TH L Y QLL CV DPETGL LPL
Sbjct: 2852 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPL 2911
Query: 469 SG-GPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAML 527
+ +GGE + R AT + GKF+G+ V++WE++ SE ++EQR L
Sbjct: 2912 TDKAAKGGELV---YTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDL 2968
Query: 528 AQQYQEGTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLE 587
+Q++ G ++VEK+ + +E+ R+ F GLR V ELL++ +ID++LY++L+
Sbjct: 2969 LRQFRTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQ 3028
Query: 588 HGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQ 647
G+ + +DV + + +R L+G IAG+ L + ++LSIY A K LL A+ LLEAQ
Sbjct: 3029 RGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQ 3088
Query: 648 AATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQ 707
A TG IIDP + +V+EA+RA ++GP+ KLLSAE+AVTGY DPYTGQ +SLFQA++
Sbjct: 3089 AGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALK 3148
Query: 708 KGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGF 767
KGLI RE G+RLL+AQ++TGG++DP SHRVP+DVA RG D+ + L P D K +
Sbjct: 3149 KGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAY 3208
Query: 768 FDPNTHENLTYLQLLERCVRDPETGLYLLPLS-----STQSPLV-DSATQQAFQNLLLSV 821
DP+T E TY +L +RC D TGL LLPLS + Q L + ++ F+ + V
Sbjct: 3209 SDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEV 3268
Query: 822 KYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQVAKLL-----EAETQRQA 876
G F+G+ V+ WELI+SEYF+ +R++LLR++R +VT+ +V K+L E ET RQ
Sbjct: 3269 PVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQE 3328
Query: 877 DIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVR 936
+ LR+ V +LL +G++ + +Q+ G + + L + VR L G G + G+
Sbjct: 3329 RLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIY 3388
Query: 937 LLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPE 996
L + +++S+Y+AMR+ LL A LLEAQAATG ++DP + L V EAV+ GVVGPE
Sbjct: 3389 LEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPE 3448
Query: 997 LYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHH 1056
L+ +L AE A+ G+RDP+SG +S+FQAM+KGL+ + RLLEAQ+ATGGIIDP H
Sbjct: 3449 LHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSH 3508
Query: 1057 HLPMPVAIQRGYVDQEMETALSSSSET---FPTPDGQGRTSYAQLLEECPRDETSGLHLL 1113
+P+ VA QRGY +EM L+ S+ F P+ +Y QLLE C D +GL LL
Sbjct: 3509 RVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLL 3568
Query: 1114 PLPESAPA-------LPTEEQVQRSLQA----VPG----AKDGTSLWDLLSSCHFTEEQR 1158
PL + A + TEE+ +R+ + +PG SLW+++ S EEQR
Sbjct: 3569 PLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQR 3628
Query: 1159 RGLLEDVQEGRTTVPQLLASVQRWVQETKLL-AQARVMVPGPRGEVPAVWLLDAGIITQE 1217
L+ D Q GR T +++ + +++T+++ Q R + A L +A II+ E
Sbjct: 3629 AQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLE 3688
Query: 1218 TLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQ 1277
T L +GT+S + E + L+GTG VAGV L S SI QA++ GLL + +
Sbjct: 3689 TYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVAR 3748
Query: 1278 RLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLS 1337
LLEAQ A+GFL+DP+ +RL+V++AV+ GLVG EL ++L AERA GY DPY+ ++S
Sbjct: 3749 LLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTIS 3808
Query: 1338 LWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVD 1397
L+QAM+K L+P E L LL QLATGG+VDP G HLP A + G L+ T L+
Sbjct: 3809 LFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSE-P 3867
Query: 1398 KDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPV 1457
+ + + DPS ++++Y QL RC D TG LLLPL D + R ++ +
Sbjct: 3868 SEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPL--------SDARKLTFRGLRKQI 3919
Query: 1458 STGRFKGCSVSLWDLLLSEYVGADKRRELVALCR-SGRAAALRQVVSAVTALVEAAERQP 1516
+ V + E R L ++ + + S + + A ++
Sbjct: 3920 TMEELVRSQV------MDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKER 3973
Query: 1517 L---QATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSV-----KRSLE 1568
L QA +G+ + +A +L AQ + +D + TV+E M V + L
Sbjct: 3974 LSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLS 4033
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
+ G + + +S+ +A+++ ++ + LLEAQ ATG IIDP E+ +L VE A
Sbjct: 4034 AERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVA 4093
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL------- 1681
+K G+F +E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4094 YKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKR 4153
Query: 1682 EAQIATGG--------IIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNT 1733
E + ++ I+DP + V AYR G D +
Sbjct: 4154 ERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ-------------------- 4193
Query: 1734 HENLTYLQLLERCVEDPE------TGLYLLQIIKKGENYVY-INEATRHVLQSRTAKMRV 1786
TYL+L E+ E E G+ II + Y I++A L R+A +
Sbjct: 4194 ----TYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRSALDQY 4249
Query: 1787 GRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIK 1846
+ F D+LS R G+ S T ++ +
Sbjct: 4250 RAGTLSITEFADMLSG---NAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGP 4306
Query: 1847 VAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPS 1906
VA I T +V + +H V GQ L LE C G+ PS
Sbjct: 4307 VAGILDTETL-----EKVSITEAMHRNLVDNITGQRL---------LEAQACTGGIIDPS 4352
Query: 1907 TREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRE 1966
T E + +A K L+ + AQ A DP T+ K+S +A+ G + E +
Sbjct: 4353 TGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQ 4412
Query: 1967 RLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEV 2009
R L+ + G +P T +PL +A+Q+ ++ A +L +V
Sbjct: 4413 RFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV 4455
Score = 970 bits (2508), Expect = 0.0
Identities = 547/1287 (42%), Positives = 810/1287 (62%), Gaps = 33/1287 (2%)
Query: 1155 EEQRRGLL---EDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDA 1211
EEQ R L E+V + + L + + + A+ G R +V A L +A
Sbjct: 2629 EEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEA 2688
Query: 1212 GIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLL 1271
GI++ E L+ LAQG + ++A + V+ L G +AG+LL+ + K S+ A++ LL
Sbjct: 2689 GILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLL 2748
Query: 1272 PTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPY 1331
G LLEAQ ASGFL+DP+ N+RL+V +AVK G+VG EL +L AERA GY DPY
Sbjct: 2749 SPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPY 2808
Query: 1332 SRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQ 1391
+ +SL+QAM+KGL+ + G+ LL+ Q+ATGGV+DPVH +P A R G D + ++
Sbjct: 2809 TGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNR 2868
Query: 1392 VLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDT-----VLEVDDHT 1446
VL D K FFDP+ + +TY QL ERCV D ETGL LLPL ++ D
Sbjct: 2869 VLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEA 2928
Query: 1447 AVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVT 1506
V G+F+G +V++W+++ SEY A++RR+L+ R+GR + +++ +
Sbjct: 2929 RDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRIT-VEKIIKIII 2987
Query: 1507 ALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRS 1566
+VE E++ + F GLR V A +L +++I R+ +L +G +V++VAE+D+V+R+
Sbjct: 2988 TVVEEQEQKG-RLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 3046
Query: 1567 LEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVE 1626
L G N IAGV ++ +++SI AL++ +L A+ LLEAQA TG IIDPA + +LTV+
Sbjct: 3047 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVD 3106
Query: 1627 EAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIA 1686
EA +AG+ G E + KLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++
Sbjct: 3107 EAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLS 3166
Query: 1687 TGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERC 1746
TGGI+DP SHRVP+DVA G DEE +R L+ P D K + DP+T E TY +L +RC
Sbjct: 3167 TGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRC 3226
Query: 1747 VEDPETGLYLLQIIKKG----ENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSS 1802
D TGL LL + +K + +Y R + ++ VG F + V+ W+L+SS
Sbjct: 3227 RPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3286
Query: 1803 PYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQG-IKVAAIRGEVTAADLFN 1861
YFT ++++EL++++ +EK+++I+ T +EE ET Q + + +R V A++L
Sbjct: 3287 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3346
Query: 1862 SRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKEL 1921
S V+ + L+ G+T + LS L V+ L+GS C+AG+ + T+E +S++EA R+ L
Sbjct: 3347 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3406
Query: 1922 IPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDP 1981
+ A A LLEAQAATGFL+DP Q+L V EAV G+V EL E+LL AE+A TGYRDP
Sbjct: 3407 LRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDP 3466
Query: 1982 ATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIY 2041
+G TI LFQAMQK L+ + +RLLE Q+ATGG+IDP H HR+P++ AY+RG +++
Sbjct: 3467 YSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMN 3526
Query: 2042 ALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSE-------H 2094
+++D K F DPNT E ++YR+L ERC +TG L P+ K A +E +
Sbjct: 3527 RVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL-KGAEKAEVVETTQVY 3585
Query: 2095 IDDETRRALEAEQVEITVGRFRGQKP-TLWALLNSEYVTEEKKLQLVRMYRTHTRRALQT 2153
++ETRRA E Q++I G G +LW ++ S+ + EE++ QL+ ++ R +
Sbjct: 3586 TEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAG-RVTKER 3644
Query: 2154 VAQLILELIEKQETSNKH--LWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELM 2211
+ +I+E+IEK E + + +RR++TA +L + II+ E L G + +E +
Sbjct: 3645 MIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREAL 3704
Query: 2212 EDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGF 2271
E + YL GT +AGV +P G ++ +SIYQA+ KG+L A +LLEAQAATGF
Sbjct: 3705 EAESAWCYLYGTGSVAGVYLP-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGF 3759
Query: 2272 VIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIV 2331
++DPV+ RL+V+E V G+VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI
Sbjct: 3760 LLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIP 3819
Query: 2332 REHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNT 2391
E +RLL+AQ+ATGG++DP +P++VAY+RGY +++ + L++PS + + + DP+T
Sbjct: 3820 TEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPST 3878
Query: 2392 HENLTYVQLLRRCVPDPDTGLYMLQLA 2418
E L+Y QLLRRC D TG +L L+
Sbjct: 3879 DERLSYTQLLRRCRRDDGTGQLLLPLS 3905
Score = 881 bits (2277), Expect = 0.0
Identities = 629/1746 (36%), Positives = 913/1746 (52%), Gaps = 133/1746 (7%)
Query: 41 RSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQ 100
R++ G +GQ S++ AM++GL+ G LLEAQ ATGG++D +PV A +
Sbjct: 2799 RAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR 2858
Query: 101 QGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEV--QLATG 158
+G E+ L T G+ DP E L Q + + V D G L + + A G
Sbjct: 2859 RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKG 2918
Query: 159 GLV----DPAQGVLVAPEPACHQGLLDRET---WHKLSELEPGTGDLR--FLNPNTLERL 209
G + A+ V + G +T W ++ E T + R L R+
Sbjct: 2919 GELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINS-EYFTAEQRRDLLRQFRTGRI 2977
Query: 210 TYHQLLERCVRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAV 269
T ++++ + ++ F + V AAELLE ++D + Q L+ G +
Sbjct: 2978 TVEKIIKIIITVVEEQEQ--KGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVR 3035
Query: 270 DVSARAEVRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLV 329
DV+ VRR L G +AGV L G K S + A + LLP A+ LLEAQA T ++
Sbjct: 3036 DVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHII 3095
Query: 330 DPITGQRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRP 389
DP T RL VDEAVRAGLV PE HE+LL AE+AVTG+ DP++G + LFQA+KKGL+ R
Sbjct: 3096 DPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPRE 3155
Query: 390 LALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLS----QAGSFSDGTHGG 445
LRLLDAQL+TGG+V P++ R+PL+ A GCLDE+T R LS A ++SD + G
Sbjct: 3156 QGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGE 3215
Query: 446 -LRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFR 504
Y +L C D TGL+ LPLS Q + + R+ V VG F+
Sbjct: 3216 PATYGELQQRCRPDQLTGLSLLPLSEKAARAR-QEELYSELQARETFEKTPVEVPVGGFK 3274
Query: 505 GRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAELSATLEQAAATA--RVTFSG 562
GR V++WEL+ SE ++EQR L +Q++ G ++VEK+ L +E+ R++FSG
Sbjct: 3275 GRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSG 3334
Query: 563 LRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQE 622
LR V ELL + ++ + +E+L+ G+ T KD+ L S + LQG+GC+AG+ L ++E
Sbjct: 3335 LRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKE 3394
Query: 623 RLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLL 682
++SIYEA +GLLR TA +LLEAQAATGF++DP N+ V EA++A V+GP++ +LL
Sbjct: 3395 KVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLL 3454
Query: 683 SAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDV 742
SAE+AVTGY DPY+G ISLFQAMQKGL++R+HGIRLLEAQIATGG+IDPVHSHRVPVDV
Sbjct: 3455 SAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3514
Query: 743 AYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQ 802
AY+RGYF + +N +L DPSDDTKGFFDPNTHENLTY QLLERCV DPETGL LLPL +
Sbjct: 3515 AYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAE 3574
Query: 803 SPLV--------DSATQQAFQNLLLSVK-YGRFQGQRVSAWELINSEYFSEGRRRQLLRR 853
V + T++AF+ + + G G +S WE++ S+ E +R QL+
Sbjct: 3575 KAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMAD 3634
Query: 854 YRQREVTLGQVAKLL-----EAETQRQADI-MLPALRSRVTVHQLLEAGIIDQQLLDQVL 907
++ VT ++ ++ + E RQ + +R R+T L EA II + + +
Sbjct: 3635 FQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLR 3694
Query: 908 AGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQ 967
GT S L + YL G G+V GV L S Q LS+YQA+++ LL VA LLEAQ
Sbjct: 3695 EGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQ 3754
Query: 968 AATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMK 1027
AATG ++DP E L+VDEAVR+G+VGPEL+ RL AE A+ G+RDP++ + +S+FQAMK
Sbjct: 3755 AATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMK 3814
Query: 1028 KGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSE--TFP 1085
K LIP E+A RLL+AQ+ATGGI+DP HLP+ VA QRGY++++ LS SE ++
Sbjct: 3815 KELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYV 3874
Query: 1086 TPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGTSLW 1145
P R SY QLL C RD+ +G LLPL ++ R L G + ++
Sbjct: 3875 DPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDA-----------RKL-TFRGLRKQITME 3922
Query: 1146 DLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPA 1205
+L+ S E L +EG T++ ++ ++Q++++ T + A V V + +
Sbjct: 3923 ELVRSQVMDEATALQL----REGLTSIEEVTKNLQKFLEGTSCI--AGVFVDATKERLSV 3976
Query: 1206 VWLLDAGIITQETLEALAQGTQSPAQVAE---------QPAVKACLWG----------TG 1246
+ GII T L + + V + + AV+ + G
Sbjct: 3977 YQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAER 4036
Query: 1247 CVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKV 1306
V G SG S+ QA++ GL+ G RLLEAQ+A+G ++DP + RL VE A K
Sbjct: 4037 AVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKR 4096
Query: 1307 GLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLL---------- 1356
GL E++E L G+ DP + +L+ Q ME+ + GL LL
Sbjct: 4097 GLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERK 4156
Query: 1357 -----QVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQ 1411
V+ +VDP G + A R GL+D QT L+ + + ++
Sbjct: 4157 TSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECE---------WEE 4207
Query: 1412 VTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLW- 1470
+T D +++ S ++DD A L + +++ ++S+
Sbjct: 4208 ITISS------SDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRS---ALDQYRAGTLSITE 4258
Query: 1471 --DLLLSEYVGADKRRELVALCRS---GRAAALRQVVS---------AVTALVEAAERQP 1516
D+L G R V S A + Q+ S V +++ +
Sbjct: 4259 FADMLSGNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEK 4318
Query: 1517 L---QATFRGLRKQVSARDLFRAQ-----LISRKTLDELSQGTTTVKEVAEMDSVKRSLE 1568
+ +A R L ++ + L AQ +I T + K + + V R
Sbjct: 4319 VSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINL 4378
Query: 1569 GGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEA 1628
G T+ +MS +AL++ L LE Q TG +I+P ++ ++EA
Sbjct: 4379 AQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEA 4438
Query: 1629 FKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-AT 1687
+ G T KL T P T +IS A+ + ++ G+RLLEA +T
Sbjct: 4439 LQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4498
Query: 1688 GGIIDP 1693
G P
Sbjct: 4499 KGYYSP 4504
Score = 869 bits (2246), Expect = 0.0
Identities = 711/2089 (34%), Positives = 1014/2089 (48%), Gaps = 390/2089 (18%)
Query: 2610 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 2665
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2561 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2620
Query: 2666 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 2712
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2621 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2677
Query: 2713 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 2772
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2678 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2734
Query: 2773 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 2832
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2735 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2792
Query: 2833 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2892
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2793 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2852
Query: 2893 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL- 2951
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L
Sbjct: 2853 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2912
Query: 2952 --AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRY 3009
A +G + E R A V+ G QG++V++WE++ + ++R+DLL ++
Sbjct: 2913 DKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQF 2972
Query: 3010 RAGTLTVEELGATLTSLLAQAQAQAR----------AEAEAGSPRPDPREALR------- 3052
R G +TVE++ + +++ + + + R AE R RE +
Sbjct: 2973 RTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGER 3032
Query: 3053 ----AATMEVKVGRLRGRAV--PVWDVLASGYVS--GAAREELL----------AEFGSG 3094
A ++ LRG V VW A +S A +++LL A+ G+G
Sbjct: 3033 SVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTG 3092
Query: 3095 TLDLPALTRRLTAIIEEAEEAPGARPQL--------------QDAWRG------------ 3128
+ PA + RLT ++EA A P+ +D + G
Sbjct: 3093 HIIDPATSARLT--VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKG 3150
Query: 3129 --PREPG-------PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQ 3168
PRE G + G D +S R G + ET A +A A A
Sbjct: 3151 LIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSD 3210
Query: 3169 EQTLRDATM-EVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLT 3227
T AT E+Q+ + + + S + AR++EL ++ A
Sbjct: 3211 PSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------R 3258
Query: 3228 RVIEETEERLSKVSFRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV----- 3278
E+T + F+G R V+ EL +S E LR G T+++V
Sbjct: 3259 ETFEKTPVEVPVGGFKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILI 3316
Query: 3279 TEMDSVKRYLEGTSCIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALV 3329
T ++ V+ + +G+ VPA + + E++ + K + G+
Sbjct: 3317 TIVEEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRT 3376
Query: 3330 LLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP-------- 3381
LL+ + ++S+ EA+ G++ LL A+ A DP
Sbjct: 3377 LLQGSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYV 3436
Query: 3382 ------------------------------YTGQQISLFQAMQKDLIVREHGIRLLEAQI 3411
Y+G ISLFQAMQK L++R+HGIRLLEAQI
Sbjct: 3437 HEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQI 3496
Query: 3412 ATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRR 3471
ATGG+IDPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL R
Sbjct: 3497 ATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLER 3556
Query: 3472 CVPDPDTGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWE 3524
CV DP+TGL +L L G A EE R A + ++ PG G+ G ++S+WE
Sbjct: 3557 CVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWE 3616
Query: 3525 LLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA 3572
++ + E++R L++ ++AG +T E + + ++ + + + R A
Sbjct: 3617 VMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTA 3676
Query: 3573 ----EAGSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDV 3607
EA + LR T ++ G + G +P ++
Sbjct: 3677 EDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQA 3736
Query: 3608 LASGYVSG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREP 3666
L G +S AR L A+ +G L P RLT ++EA P+L D
Sbjct: 3737 LKKGLLSAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER- 3793
Query: 3667 GPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVW 3726
A G D Q + +E A R + L + R F P+ V
Sbjct: 3794 --AVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV- 3849
Query: 3727 DVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------- 3772
YL++ D+ L + V + V T+ERLS
Sbjct: 3850 -AYQRGYLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGT 3897
Query: 3773 -----------KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 3821
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++
Sbjct: 3898 GQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKF 3955
Query: 3822 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 3881
LEGTSCIAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L
Sbjct: 3956 LEGTSCIAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGL 4010
Query: 3882 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 3941
+L+VEEAV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLL
Sbjct: 4011 KLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLL 4070
Query: 3942 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQ 4001
EAQIATGG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+Q
Sbjct: 4071 EAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQ 4130
Query: 4002 LLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLF 4061
L+ RC+ DP TGL +L L + S+ R V P + G+ +SV+E
Sbjct: 4131 LMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYEA-- 4184
Query: 4062 YREVSEDRRQDL-LSRYRA--STLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREA 4118
YR+ D + L LS +T+ + S++
Sbjct: 4185 YRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMI----------------------- 4221
Query: 4119 LRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIE 4178
+ R GR + D +A + R+A L ++ +GTL + L+
Sbjct: 4222 ---------IDRRSGRQYDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS---- 4264
Query: 4179 EAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ 4238
G++G + G + + A +R Q
Sbjct: 4265 -----------------------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLA 4295
Query: 4239 TLRDATMEVQRGQFQG-------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDL 4290
+ D T E G G VS+ + + + + LL AQ G +
Sbjct: 4296 SWSDPTEET--GPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI----- 4348
Query: 4291 VAVLTRVIEETEER--LSKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTL 4343
+ T ER ++ +GL ++ ++ + G P T ++
Sbjct: 4349 ------IDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4402
Query: 4344 QEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQA 4403
+ ++ +R+LE G++ P D PGR + + +A+ +G + TA L + A
Sbjct: 4403 KGWLYYEAGQRFLEVQYLTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGA 4457
Query: 4404 ATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 4451
+ ++ P L++S ++A+ +V +LL +A ++ GY PY+
Sbjct: 4458 YSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4506
Score = 852 bits (2202), Expect = 0.0
Identities = 715/2192 (32%), Positives = 1042/2192 (47%), Gaps = 408/2192 (18%)
Query: 1960 VNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEAL----RLLEVQVATGG 2015
+ +E + LK+E T ++ +T QA+Q+ + + ++L R +E + A
Sbjct: 2489 LQQEAKLLQLKSEEMQTVQQEQLLQET----QALQQSFLSEKDSLLQRERFIEQEKAKLE 2544
Query: 2016 VI---DPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERC 2072
+ + +L E ++ + ++ L++ + R+R + + ELQ+
Sbjct: 2545 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2604
Query: 2073 RPQEDTGWVLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVT 2132
+ + +L N+ R+ + +E RA A E+T + K
Sbjct: 2605 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL----------- 2653
Query: 2133 EEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSAII 2192
+ R AL A E +H F G+RR+++A L + I+
Sbjct: 2654 ------------PNGRDALDGPA---------AEAEPEHS-FDGLRRKVSAQRLQEAGIL 2691
Query: 2193 TEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKG 2252
+ E LQ L G +T EL + V+ YL+G S IAG+L+ A + EK+S+Y A+ +
Sbjct: 2692 SAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN-----EKLSVYAALQRQ 2746
Query: 2253 VLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTD 2312
+L PGTAL+LLEAQAA+GF++DPVRN RL+V E V GVVG E+ KLLSAERAVTGY D
Sbjct: 2747 LLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKD 2806
Query: 2313 PYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2372
PYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM
Sbjct: 2807 PYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEM 2866
Query: 2373 NRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL---AGRGSAVHQLSE 2429
NRVLADPSDDTKGFFDPNTHENLTY+QLL RCV DP+TGL +L L A +G +
Sbjct: 2867 NRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDS 2926
Query: 2430 ELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATL 2489
E R A V+ G QG++V++WE++ + ++R+DLL ++R G +TVE++ +
Sbjct: 2927 EARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKII 2986
Query: 2490 TSLLAQAQAQAR----------AEAEAGSPRPDPREALR-----------AATMEVKVGR 2528
+++ + + + R AE R RE + A ++
Sbjct: 2987 ITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRA 3046
Query: 2529 LRGRAV--PVWDVLASGYVS--RAAREELL----------AEFGSGTLDLPALTRRLTAI 2574
LRG V VW A +S A +++LL A+ G+G + PA + RLT
Sbjct: 3047 LRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLT-- 3104
Query: 2575 IEEAEEAPGARPQ--------------------------LQDARRG--PREPG------- 2599
++EA A P+ Q ++G PRE G
Sbjct: 3105 VDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQ 3164
Query: 2600 PAGRGDGDSGRSQR--------EGQGEGETQEAAAAA---AAARRQEQTLRDATM-EVQR 2647
+ G D +S R G + ET A +A A A T AT E+Q+
Sbjct: 3165 LSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQ 3224
Query: 2648 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVS 2707
+ + + S + AR++EL ++ A E+T +
Sbjct: 3225 RCRPDQLTGLSLLPLSEKAARARQEELYSELQA------------RETFEKTPVEVPVGG 3272
Query: 2708 FRGLRRQVSASELHTSGIL----GPETLRDLAQGTKTLQEV-----TEMDSVKRYLEGTS 2758
F+G R V+ EL +S E LR G T+++V T ++ V+ +
Sbjct: 3273 FKG--RTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERL 3330
Query: 2759 CIAGVL--VPAKD-------QPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDP 2809
+G+ VPA + + E++ + K + G+ LL+ +
Sbjct: 3331 SFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLE 3390
Query: 2810 VRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDP---------------------- 2847
++S+ EA+ G++ LL A+ A DP
Sbjct: 3391 DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELH 3450
Query: 2848 ----------------YTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRV 2891
Y+G ISLFQAMQK L++R+HGIRLLEAQIATGG+IDPVHSHRV
Sbjct: 3451 EQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRV 3510
Query: 2892 PVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL 2951
PVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+TGL +L L
Sbjct: 3511 PVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPL 3570
Query: 2952 AGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYREVSEDRRQD 3004
G A EE R A + ++ PG G+ G ++S+WE++ + E++R
Sbjct: 3571 KGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQ 3630
Query: 3005 LLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EAGSPRPDPR 3048
L++ ++AG +T E + + ++ + + + R A EA +
Sbjct: 3631 LMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETY 3690
Query: 3049 EALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYVSG-AAREE 3086
LR T ++ G + G +P ++ L G +S AR
Sbjct: 3691 NLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLL 3750
Query: 3087 LLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQ 3146
L A+ +G L P RLT ++EA P+L D A G D Q
Sbjct: 3751 LEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTGYRDPYTEQ 3805
Query: 3147 REGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRD 3206
+ +E A R + L + R F P+ V YL++ D
Sbjct: 3806 TISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRGYLNKDTHD 3862
Query: 3207 ELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------------KVS 3241
+ L + V + V T+ERLS K++
Sbjct: 3863 Q-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLT 3911
Query: 3242 FRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPA 3301
FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSCIAGV V A
Sbjct: 3912 FRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSCIAGVFVDA 3969
Query: 3302 KDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVG 3361
+E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEEAV G+VG
Sbjct: 3970 -----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVG 4024
Query: 3362 GEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVH 3421
E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIATGG+IDP
Sbjct: 4025 PEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEE 4084
Query: 3422 SHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLY 3481
SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTY+QL+ RC+ DP TGL
Sbjct: 4085 SHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLC 4144
Query: 3482 MLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLS 3541
+L L + S+ R V P + G+ +SV+E
Sbjct: 4145 LLPLKEKKRERKTSSKSSVRKRRVVIVDPET----GKEMSVYE----------------- 4183
Query: 3542 RYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRA 3601
YR G + + T L Q E S + + R GR
Sbjct: 4184 AYRKGLIDHQ------TYLELSEQECEWEEITISSS--------DGVVKSMIIDRRSGRQ 4229
Query: 3602 VPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWR 3661
+ D +A + +A L ++ +GTL + L+
Sbjct: 4230 YDIDDAIAKNLIDRSA----LDQYRAGTLSITEFADMLS--------------------- 4264
Query: 3662 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG- 3720
G++G + G + + A +R Q + D T E G G
Sbjct: 4265 ------------GNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEET--GPVAGI 4310
Query: 3721 ------RPVSVWDVLFSSYLSEARRDELL-AQHAAGALGLPDLVAVLTRVIEETEER--L 3771
VS+ + + + + LL AQ G + + T ER +
Sbjct: 4311 LDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGI-----------IDPSTGERFPV 4359
Query: 3772 SKVSFRGLRRQVSASELHTS-----GILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTS 3826
+ +GL ++ ++ + G P T ++ + ++ +R+LE
Sbjct: 4360 TDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQY 4419
Query: 3827 CIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVE 3886
G++ P D PGR + + +A+ +G + TA L + A + ++ P L++S +
Sbjct: 4420 LTGGLIEP--DTPGR---VPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYK 4474
Query: 3887 EAVAAGVVGGEIQEKLL-SAERAVTGYTDPYT 3917
+A+ +V +LL +A ++ GY PY+
Sbjct: 4475 DALDRSMVEEGTGLRLLEAAAQSTKGYYSPYS 4506
Score = 727 bits (1876), Expect = 0.0
Identities = 710/2292 (30%), Positives = 1038/2292 (45%), Gaps = 316/2292 (13%)
Query: 3017 EELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLAS 3076
EE+ A S A +A E E G R + + LR+ + ++ R R + +
Sbjct: 1952 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE-QAELEAARQRQLAAEEERRR 2010
Query: 3077 GYVSGAAREELLAEFGSGTLDLPAL--TRRLTAIIEEAE------EAPGARPQLQDAWRG 3128
++ L AE + AL RL A +EEA E AR QLQ A
Sbjct: 2011 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEA 2069
Query: 3129 PREPGPAGRGDGDSGRSQREGQGEGETQEAAAA-------AAAARRQEQTLRDATMEVQR 3181
++ A Q+E + + Q+ + A AARR + +A ++ +R
Sbjct: 2070 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2129
Query: 3182 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAV-LTRVIEETEERLSKV 3240
Q R + EA R + A+ A A A L + E+ R ++
Sbjct: 2130 EAAQSR----------RQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2179
Query: 3241 SFRGLR-RQVSASELHTSGILGPETLRDLAQGTKTLQ----EVTEMDSVKRYL-EGTSCI 3294
LR +Q + +E+ +TLR AQ + L ++ E D K L E +
Sbjct: 2180 EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRL 2239
Query: 3295 AGVLVPAKDQPGRQEK--------MSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRN 3346
A Q + E+ M + + AL+L + F+ +
Sbjct: 2240 KAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEK 2299
Query: 3347 LRLSVEEAVAAGVVGGE----------------------IQEKLLSAERAVTGYTDPYTG 3384
++ EEA V E ++EK+ + + A +
Sbjct: 2300 MKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2359
Query: 3385 QQ---ISLFQA---------MQKDLIVREHGI-RLLEA----QIATGGVIDPVHSHRVPV 3427
QQ ++ QA M + L G R LEA Q+ + + +
Sbjct: 2360 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2419
Query: 3428 DVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLL--RRCVPDPDTGLYMLQL 3485
A R D + R A+ + + T E +T VQ L +R D D +
Sbjct: 2420 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI 2479
Query: 3486 AGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRA 3545
A +L +E + L + Q Q + + L +SE + LL R R
Sbjct: 2480 AELEREKEKLQQEAK--LLQLKSEEMQTVQQEQLLQETQALQQSFLSE--KDSLLQRERF 2535
Query: 3546 GTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPV- 3604
+L +A+AQ Q R E + + + A+ME R V
Sbjct: 2536 IEQEKAKLEQLFQDEVAKAQ-QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2594
Query: 3605 --WDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRG 3662
+ L +EELLAE + L +L + E+ A ++ +
Sbjct: 2595 RKQEELQQLEQQRRQQEELLAE------ENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2648
Query: 3663 PREPGPAGRG--DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQG 3720
+ P GR DG + ++ E +G ++ +A R QE + A E+QR QG
Sbjct: 2649 ATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ----RLQEAGILSAE-ELQR-LAQG 2702
Query: 3721 RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 3780
+ E R E + + G + L+ ++ T E+LS + L+
Sbjct: 2703 HTT----------VDELARREDVRHYLQGRSSIAGLL------LKATNEKLSV--YAALQ 2744
Query: 3781 RQVSA---------SELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 3831
RQ+ + ++ + +L P R L + V + + L + G
Sbjct: 2745 RQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGY 2804
Query: 3832 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 3891
P Q ++S++QAM KG++ + LLEAQ ATG VIDPV + R+ V+ A
Sbjct: 2805 KDPYTGQ-----QISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRR 2859
Query: 3892 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEA--QIATGG 3949
G E+ L G+ DP T + ++ Q +++ + E G+ LL + A GG
Sbjct: 2860 GYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGG 2919
Query: 3950 VI--------DPVHSHRVPVDVAYRRG------------YFDEEMNRVLADPSDDTKGFF 3989
+ D V +G YF E R L +
Sbjct: 2920 ELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITV 2979
Query: 3990 DPNTHENLTYVQL-----------LRRCVPDP--------DTGLYMLQLAGRGSAVHQLS 4030
+ +T V+ LR VP D LY QL +V ++
Sbjct: 2980 EKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQ-QLQRGERSVRDVA 3038
Query: 4031 E--ELRCALRDARVTPGSGALQ-GQSVSVWELLFYREVSEDRRQDLLSRYRASTLTVEEL 4087
E +R ALR A V G + GQ +S++ L ++DLL A L +
Sbjct: 3039 EVDTVRRALRGANVIAGVWLEEAGQKLSIYNAL---------KKDLLPSDMAVALLEAQA 3089
Query: 4088 GAT-LTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGR--LRGRAVPVWDVLAS 4144
G + A+ AG P+ E L +A V R G++V ++ L
Sbjct: 3090 GTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKK 3149
Query: 4145 GYVSRAAREELL-AEFGSGTLDLPALTRRLTAII--------EEAEEAPGARPQLQDAWR 4195
G + R LL A+ +G + P+ + R+ + EE A A A+
Sbjct: 3150 GLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYS 3209
Query: 4196 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQ---------TLRDATME 4246
P PA G+ + R Q G + + AA RQE+ T +E
Sbjct: 3210 DPSTGEPATYGELQ--QRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVE 3267
Query: 4247 VQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEE-RL 4305
V G F+GR V+VW+++ S Y + +R ELL Q G + + ++ +L ++EE E R
Sbjct: 3268 VPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQ 3327
Query: 4306 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 4365
++SF GLR V ASEL SG+L L G T+++++E+ SV+ L+G+ C+AG+
Sbjct: 3328 ERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGI 3387
Query: 4366 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 4425
+ +EK+SIY+AM +G+LR TA +LLEAQAATGF++DPVRN RL V EAV A
Sbjct: 3388 YLE-----DTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKA 3442
Query: 4426 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 4485
GVVG E+ E+LLSAE+AVTGY DPY+G ISLFQAMQK L++R+HGIRLLEAQIATGG+I
Sbjct: 3443 GVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGII 3502
Query: 4486 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 4545
DPVHSHRVPVDVAY+RGYF EEMNRVLADPSDDTKGFFDPNTHENLTY QLL RCV DP+
Sbjct: 3503 DPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPE 3562
Query: 4546 TGLYMLQLAGRGSA------VHQLSEELRCALRDARV-TPGSGALQGQSVSVWELLFYRE 4598
TGL +L L G A EE R A + ++ PG G+ G ++S+WE++
Sbjct: 3563 TGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDL 3622
Query: 4599 VSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQ------------AQARAEA----EA 4642
+ E++R L++ ++AG +T E + + ++ + + + R A EA
Sbjct: 3623 IPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEA 3682
Query: 4643 GSPRPDPREALRAATMEVK--------------VGRLRGRAVP-------VWDVLASGYV 4681
+ LR T ++ G + G +P ++ L G +
Sbjct: 3683 RIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLL 3742
Query: 4682 SG-AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRG 4740
S AR L A+ +G L P RLT ++EA P+L D A G
Sbjct: 3743 SAEVARLLLEAQAATGFLLDPVKGERLT--VDEAVRKGLVGPELHDRLLSAER---AVTG 3797
Query: 4741 DGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSS 4800
D Q + +E A R + L + R F P+ V
Sbjct: 3798 YRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFH-LPLEV--AYQRG 3854
Query: 4801 YLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLS-------------------- 4840
YL++ D+ L + V + V T+ERLS
Sbjct: 3855 YLNKDTHDQ-----------LSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLP 3903
Query: 4841 -----KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSC 4895
K++FRGLR+Q++ EL S ++ T L +G +++EVT+ +++++LEGTSC
Sbjct: 3904 LSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTK--NLQKFLEGTSC 3961
Query: 4896 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 4955
IAGV V A +E++S+YQAM KG++RPGTA LLEAQAATG+VIDP++ L+L+VEE
Sbjct: 3962 IAGVFVDA-----TKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEE 4016
Query: 4956 AVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 5015
AV G+VG E ++KLLSAERAVTGY DPY+G+ ISLFQAM+K LI+++HGIRLLEAQIAT
Sbjct: 4017 AVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIAT 4076
Query: 5016 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRAT 5075
GG+IDP SHR+PV+VAY+RG FDEEMN +L DPSDDTKGFFDPNT ENLTYLQL++R
Sbjct: 4077 GGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCI 4136
Query: 5076 LDPETGLLFLSL 5087
DP+TGL L L
Sbjct: 4137 TDPQTGLCLLPL 4148
Score = 619 bits (1597), Expect = e-176
Identities = 476/1531 (31%), Positives = 736/1531 (48%), Gaps = 227/1531 (14%)
Query: 40 ARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKAL 99
A IAGV++E +GQ S+Y A+++ LLP+ + ALLEAQA TG ++D A L V +A+
Sbjct: 3050 ANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEAV 3109
Query: 100 QQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGG 159
+ GLVG E EKLL+AE+A TGY DPY G+ ++LFQA+ K ++ R G L+ QL+TGG
Sbjct: 3110 RAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTGG 3169
Query: 160 LVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCV 219
+VDP++ V + AC +G LD ET LS P + +P+T E TY +L +RC
Sbjct: 3170 IVDPSKSHRVPLDVACARGCLDEETSRALS--APRADAKAYSDPSTGEPATYGELQQRCR 3227
Query: 220 RAPGSGLALLPL------------------KITFRS----------MGGAVSAAELLEVG 251
+GL+LLPL + TF G V+ EL+
Sbjct: 3228 PDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISSE 3287
Query: 252 ILD-EQAVQGLREGRLAAV--------------DVSARAEVRRYLEGTGS--------VA 288
EQ + LR+ R V +V + R G + +
Sbjct: 3288 YFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLAS 3347
Query: 289 GVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAG-- 346
GV+ + + + + L +G+ LL+ + T +++ + EA+R G
Sbjct: 3348 GVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGLL 3407
Query: 347 -----------------LVSPELHEQLLVAE-------------------QAVTGHHDPF 370
LV P +++L V E +AVTG+ DP+
Sbjct: 3408 RATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDPY 3467
Query: 371 SGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQR 430
SGS I LFQAM+KGLV R +RLL+AQ+ATGG++ P R+P++ A + G E+ R
Sbjct: 3468 SGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMNR 3527
Query: 431 QLSQ-----AGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPP-FIK 484
L+ G F TH L Y QLL CV DPETGL LPL G + + + +
Sbjct: 3528 VLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVETTQVYTE 3587
Query: 485 YSTRQALSTATATV-SVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAA 543
TR+A + G G +SLWE++ S+ I EQRA L +Q G ++ E++
Sbjct: 3588 EETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMII 3647
Query: 544 ELSATLEQAAATAR---VTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLA 600
+ +E+ + ++ +R +T +L +A II + Y L G + ++
Sbjct: 3648 IIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAE 3707
Query: 601 SAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANK 660
SA YL GTG +AG+ LPGS++ LSIY+A KGLL A +LLEAQAATGF++DP +
Sbjct: 3708 SAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGE 3767
Query: 661 GHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLL 720
+V+EA+R ++GP++ +LLSAERAVTGY DPYT Q ISLFQAM+K LI E +RLL
Sbjct: 3768 RLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLL 3827
Query: 721 EAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQ 780
+AQ+ATGG++DP +P++VAY+RGY ++ + L +PS + + + DP+T E L+Y Q
Sbjct: 3828 DAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQ 3886
Query: 781 LLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSE 840
LL RC RD TG LLPLS A + F+ L ++++ EL+ S+
Sbjct: 3887 LLRRCRRDDGTGQLLLPLS--------DARKLTFRGL----------RKQITMEELVRSQ 3928
Query: 841 YFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQ 900
E QL E + K LE T A + + A + R++V+Q ++ GII
Sbjct: 3929 VMDEATALQLREGLTSIEEVTKNLQKFLEG-TSCIAGVFVDATKERLSVYQAMKKGIIRP 3987
Query: 901 QLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVA 960
++L A G V G +L++ +A+R ++GP
Sbjct: 3988 GTAFELLEAQ-------------------AATGYVIDPIKGLKLTVEEAVRMGIVGPEFK 4028
Query: 961 LALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQV 1020
LL A+ A DP+S + +S+ +A+++G++ + RL A+ A G DP ++
Sbjct: 4029 DKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRL 4088
Query: 1021 SVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSS 1080
V A K+GL E L + T G DP + +L
Sbjct: 4089 PVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENL---------------------- 4126
Query: 1081 SETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPT--EEQVQRSLQAVPGA 1138
+Y QL+E C D +GL LLPL E T + V++ +
Sbjct: 4127 -------------TYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDP 4173
Query: 1139 KDGTSLWDLLSSCHFTEEQRRGLLE-----DVQEGRTTVPQLLASVQRWVQETKLLAQAR 1193
+ G + E R+GL++ ++ E ++ S V ++ ++ +
Sbjct: 4174 ETGKEM-------SVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRR- 4225
Query: 1194 VMVPGPRGEVPAVWLLDAGIITQETLEALAQGTQSPAQVAE------------------- 1234
G + ++ + +I + L+ GT S + A+
Sbjct: 4226 ---SGRQYDIDDA--IAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSS 4280
Query: 1235 -----QPAV---KACLWG-----TGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLE 1281
PAV + W TG VAG+L + K SI +A+ L+ GQRLLE
Sbjct: 4281 SSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLE 4340
Query: 1282 AQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQA 1341
AQ +G ++DP +R V DAV GLV + + +++ A++A G+ DP ++ +S QA
Sbjct: 4341 AQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQA 4400
Query: 1342 MEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNK 1401
++KG + G L+VQ TGG+++P +P A + G +D +T+Q L V +K
Sbjct: 4401 LKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSK 4460
Query: 1402 FFFDPSARDQVTYQQLRERCVCDSETGLLLL 1432
+ P + +++Y+ +R + + TGL LL
Sbjct: 4461 YLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4491
Score = 350 bits (897), Expect = 3e-95
Identities = 288/927 (31%), Positives = 451/927 (48%), Gaps = 110/927 (11%)
Query: 4243 ATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE 4302
AT+ G+FQG+ V++W+++ S Y + +R +LL Q G + + ++ ++ V+EE E
Sbjct: 2935 ATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITVVEEQE 2994
Query: 4303 ERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCI 4362
++ ++ F GLR V A+EL S ++ E + L +G +++++V E+D+V+R L G + I
Sbjct: 2995 QK-GRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRALRGANVI 3053
Query: 4363 AGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEA 4422
AGV + Q K+SIY A+ K +L A+ LLEAQA TG +IDP + RL+V+EA
Sbjct: 3054 AGVWLEEAGQ-----KLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEA 3108
Query: 4423 VAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATG 4482
V AG+VG E EKLLSAE+AVTGY DPYTGQ +SLFQA++K LI RE G+RLL+AQ++TG
Sbjct: 3109 VRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTG 3168
Query: 4483 GVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVP 4542
G++DP SHRVP+DVA RG DEE +R L+ P D K + DP+T E TY +L +RC P
Sbjct: 3169 GIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRCRP 3228
Query: 4543 DPDTGLYMLQLAGRGSAVHQLSEELRCALRDARV---TPGS---GALQGQSVSVWELLFY 4596
D TGL +L L+ + + Q EEL L+ TP G +G++V+VWEL+
Sbjct: 3229 DQLTGLSLLPLSEKAARARQ--EELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISS 3286
Query: 4597 REVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAE-AGSPRPDPREAL-- 4653
+ ++RQ+LL ++R G +TVE++ L +++ + + + +G P P L
Sbjct: 3287 EYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLA 3346
Query: 4654 -----RAATMEVKVGR---------------LRGRA-------------VPVWDVLASGY 4680
RA ++K G+ L+G V +++ + G
Sbjct: 3347 SGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGL 3406
Query: 4681 VSGAAREELL-AEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGR 4739
+ LL A+ +G L P +RL + EA +A P+L + E G
Sbjct: 3407 LRATTAALLLEAQAATGFLVDPVRNQRL--YVHEAVKAGVVGPELHEQLLSA-EKAVTGY 3463
Query: 4740 GDGDSGRSQREGQGEGETQEAAAAAAAARRQEQTLRDATMEVQRGQF----QGRPVSVWD 4795
D SG + Q A ++ +R ++ G V V
Sbjct: 3464 RDPYSGSTISLFQ---------AMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDV 3514
Query: 4796 VLFSSYLSEARRDELLAQHAAGALGLPD--------LVAVLTRVIEETEERLSKVSFRGL 4847
Y SE + +LA + G D +L R +E+ E L + +G
Sbjct: 3515 AYQRGYFSE-EMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGA 3573
Query: 4848 RRQ--VSASELHTSGILG---PETLRDLAQG------TKTLQEVTEMDSVK--------- 4887
+ V ++++T ET D+ G T +L EV + D +
Sbjct: 3574 EKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMA 3633
Query: 4888 -----RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFV 4942
R + I + + K + RQ+ ++ Y V R TA L EA+ +
Sbjct: 3634 DFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDY----VRRRLTAEDLFEARIISLET 3689
Query: 4943 IDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVR 5002
+ +R S+ EA+ A E L +V G P + Q +S++QA++K L+
Sbjct: 3690 YNLLREGTRSLREALEA-----ESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSA 3744
Query: 5003 EHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTH 5062
E LLEAQ ATG ++DPV R+ VD A R+G E++ L G+ DP T
Sbjct: 3745 EVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTE 3804
Query: 5063 ENLTYLQLLQRATLDPETGLLFLSLSL 5089
+ ++ Q +++ + E L L L
Sbjct: 3805 QTISLFQAMKKELIPTEEALRLLDAQL 3831
Score = 347 bits (889), Expect = 2e-94
Identities = 202/360 (56%), Positives = 242/360 (67%), Gaps = 25/360 (6%)
Query: 4746 RSQREGQGEGETQEAAAAAAAARRQ----EQTLRDATMEVQRGQFQGRPVSVWDVLFSSY 4801
+ +++ Q E E Q A+ ARR+ E+ +R E+Q+ + Q R +
Sbjct: 2561 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2620
Query: 4802 LSE-------------ARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLR 4848
L E A +E+ A A LP+ L E E + SF GLR
Sbjct: 2621 LREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEP---EHSFDGLR 2677
Query: 4849 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 4908
R+VSA L +GIL E L+ LAQG T+ E+ + V+ YL+G S IAG+L+ A +
Sbjct: 2678 RKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATN--- 2734
Query: 4909 RQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQE 4968
EK+S+Y A+ + +L PGTAL+LLEAQAA+GF++DPVRN RL+V EAV GVVG E+
Sbjct: 2735 --EKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHH 2792
Query: 4969 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVP 5028
KLLSAERAVTGY DPYTGQQISLFQAMQK LIVREHGIRLLEAQIATGGVIDPVHSHRVP
Sbjct: 2793 KLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 2852
Query: 5029 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLS 5088
VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLL+R DPETGL L L+
Sbjct: 2853 VDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLT 2912
Score = 254 bits (648), Expect = 2e-66
Identities = 137/307 (44%), Positives = 206/307 (67%), Gaps = 8/307 (2%)
Query: 4784 GQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETE--ERLSK 4841
G G +S+W+V+ S + E +R +L+A AG + ++ ++ +IE+TE +
Sbjct: 3605 GSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGL 3664
Query: 4842 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 4901
S+ +RR+++A +L + I+ ET L +GT++L+E E +S YL GT +AGV +
Sbjct: 3665 ASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYL 3724
Query: 4902 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 4961
P G ++ +SIYQA+ KG+L A +LLEAQAATGF++DPV+ RL+V+EAV G+
Sbjct: 3725 P-----GSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGL 3779
Query: 4962 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 5021
VG E+ ++LLSAERAVTGY DPYT Q ISLFQAM+K+LI E +RLL+AQ+ATGG++DP
Sbjct: 3780 VGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDP 3839
Query: 5022 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETG 5081
+P++VAY+RGY +++ + L++PS + + + DP+T E L+Y QLL+R D TG
Sbjct: 3840 RLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQLLRRCRRDDGTG 3898
Query: 5082 LLFLSLS 5088
L L LS
Sbjct: 3899 QLLLPLS 3905
Score = 107 bits (267), Expect = 3e-22
Identities = 73/212 (34%), Positives = 111/212 (52%), Gaps = 5/212 (2%)
Query: 4347 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4406
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4292 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4346
Query: 4407 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 4466
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4347 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4406
Query: 4467 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 4526
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4407 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4466
Query: 4527 THENLTYVQLLRRCVPDPDTGLYMLQLAGRGS 4558
T ++Y L R + + TGL +L+ A + +
Sbjct: 4467 TKLKISYKDALDRSMVEEGTGLRLLEAAAQST 4498
Score = 107 bits (266), Expect = 4e-22
Identities = 73/210 (34%), Positives = 109/210 (51%), Gaps = 5/210 (2%)
Query: 4881 TEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATG 4940
T++ S E T +AG+L EK+SI +AM + ++ T LLEAQA TG
Sbjct: 4292 TQLASWSDPTEETGPVAGIL-----DTETLEKVSITEAMHRNLVDNITGQRLLEAQACTG 4346
Query: 4941 FVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLI 5000
+IDP R V +AV G+V + +++ A++A G+ DP T ++S QA++K +
Sbjct: 4347 GIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWL 4406
Query: 5001 VREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPN 5060
E G R LE Q TGG+I+P RVP+D A +RG D + L D +K P
Sbjct: 4407 YYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPK 4466
Query: 5061 THENLTYLQLLQRATLDPETGLLFLSLSLQ 5090
T ++Y L R+ ++ TGL L + Q
Sbjct: 4467 TKLKISYKDALDRSMVEEGTGLRLLEAAAQ 4496
Score = 105 bits (261), Expect = 2e-21
Identities = 69/217 (31%), Positives = 114/217 (52%), Gaps = 3/217 (1%)
Query: 13 GTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQ 72
G++S+ S P L + + P + +AG+ + + S+ AM + L+ GQ
Sbjct: 4278 GSSSSYPIS-PAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQ 4336
Query: 73 ALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLA 132
LLEAQA TGG++D + G+ PV+ A+ +GLV + +++ A++A G+ DP K++
Sbjct: 4337 RLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMS 4396
Query: 133 LFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLLDRETWHKLSELE 192
QA+ K + GQ +LEVQ TGGL++P V + A +G +D T KL ++
Sbjct: 4397 AAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDV- 4455
Query: 193 PGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALL 229
G P T +++Y L+R + G+GL LL
Sbjct: 4456 -GAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLL 4491
Score = 70.5 bits (171), Expect = 4e-11
Identities = 61/227 (26%), Positives = 102/227 (44%), Gaps = 17/227 (7%)
Query: 4832 IEETEERLS--KVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRY 4889
++ T+ERLS + +G+ R +A EL + + + T++E M V
Sbjct: 3967 VDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPE 4026
Query: 4890 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 4949
+ A V P + +S++QAM KG++ + LLEAQ ATG +IDP +
Sbjct: 4027 FKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESH 4086
Query: 4950 RLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 5009
RL VE A G+ E+ E L G+ DP T + ++ Q M++ + + G+ LL
Sbjct: 4087 RLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLL 4146
Query: 5010 -------EAQIATGG--------VIDPVHSHRVPVDVAYRRGYFDEE 5041
E + ++ ++DP + V AYR+G D +
Sbjct: 4147 PLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQ 4193
Score = 60.8 bits (146), Expect = 3e-08
Identities = 32/119 (26%), Positives = 61/119 (51%)
Query: 4971 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 5030
L ++ G T +++S++ A+Q+ L+ + LLEAQ A+G ++DPV + R+ V+
Sbjct: 2719 LQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVN 2778
Query: 5031 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSL 5089
A + G E++ L G+ DP T + ++ Q +Q+ + E G+ L +
Sbjct: 2779 EAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQI 2837
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4254 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4310
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4227 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4282
Query: 4311 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4359
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4283 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4342
Query: 4360 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4386
+C G++ P+ + P + KMS QA+
Sbjct: 4343 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4402
Query: 4387 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4446
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4403 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4462
Query: 4447 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 4487
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4463 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4504
Score = 54.7 bits (130), Expect = 2e-06
Identities = 66/282 (23%), Positives = 109/282 (38%), Gaps = 52/282 (18%)
Query: 4788 GRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKV---SF 4844
GR + D + + + + D Q+ AG L + + +L+ R S V S
Sbjct: 4227 GRQYDIDDAIAKNLIDRSALD----QYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS 4282
Query: 4845 RGLRRQVSASELHT-----------SGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGT 4893
+ VS ++L + +GIL ETL ++ + + + + +R LE
Sbjct: 4283 YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQ 4342
Query: 4894 SCIAGVLVPAK---------------------------------DQPGRQEKMSIYQAMW 4920
+C G++ P+ + P + KMS QA+
Sbjct: 4343 ACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALK 4402
Query: 4921 KGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGY 4980
KG L LE Q TG +I+P R+ ++EA+ G V +KL
Sbjct: 4403 KGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYL 4462
Query: 4981 TDPYTGQQISLFQAMQKDLIVREHGIRLLEAQI-ATGGVIDP 5021
T P T +IS A+ + ++ G+RLLEA +T G P
Sbjct: 4463 TCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSP 4504
>gi|58530842 desmoplakin isoform II [Homo sapiens]
Length = 2272
Score = 382 bits (981), Expect = e-105
Identities = 283/872 (32%), Positives = 439/872 (50%), Gaps = 91/872 (10%)
Query: 1263 AQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAER 1322
++ V DGL +L E Q+ +D L + SVE+ V E+ L A
Sbjct: 1365 SKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEE------VASEIQPFLRGAGS 1418
Query: 1323 AAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRL 1382
A P + SL +A K L+ + LL+ Q ATGG++DP L +A
Sbjct: 1419 IAGASASP--KEKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIAR 1476
Query: 1383 GLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEV 1442
L+D Q + A +K F DP + V+ + ++ + D ETG+ LL + V
Sbjct: 1477 DLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVV 1536
Query: 1443 DDHTAVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALR--- 1499
D +V L P +G DL S D ++ V + + ++
Sbjct: 1537 DPVNSVFL-----PKDVALARGLIDR--DLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKE 1589
Query: 1500 --QVVSAVTALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEV 1557
++ L+ + +++ + +F+G+R+ V+ +L + ++ T++EL G + EV
Sbjct: 1590 RCRIEPHTGLLLLSVQKRSM--SFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEV 1647
Query: 1558 AEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDP 1617
E +K L+G + IAG+ + T++++ I EA++ ++RPGTAL LLEAQAATGFI+DP
Sbjct: 1648 GER--IKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDP 1705
Query: 1618 AENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHG 1677
N +L VEEA+K G+ G E KLLSAERAVTGY DP TG ISLFQAM K+LI + HG
Sbjct: 1706 VSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHG 1765
Query: 1678 IRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENL 1737
IRLLEAQIATGGIIDP SHR+PVD+AY+ GYF+EE++ IL+DPSDDTKGFFDPNT ENL
Sbjct: 1766 IRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENL 1825
Query: 1738 TYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSR---------TAKMRVGR 1788
TYLQL ERC++D ETGL LL + +K + + + ++ L+ R +M V
Sbjct: 1826 TYLQLKERCIKDEETGLCLLPLKEKKKQ---VQTSQKNTLRKRRVVIVDPETNKEMSVQE 1882
Query: 1789 -FADQVVSF------------WDLL-------SSPYFTEDRK-----------------R 1811
+ ++ + W+ + S+ DRK R
Sbjct: 1883 AYKKGLIDYETFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDR 1942
Query: 1812 ELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLFNS----RVIDQ 1867
+ +Y + S L + ++I+ G+ ++ G + D+F+S V
Sbjct: 1943 KFFDQYRSGSLSLTQFADMISL--------KNGVGTSSSMGSGVSDDVFSSSRHESVSKI 1994
Query: 1868 KTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFA 1927
T+ ++R + S LE S IA + E +S+ E + ++ +
Sbjct: 1995 STISSVRNLTIRSSSFSDT------LEESSPIAAIFDTENLEKISITEGIERGIVDSITG 2048
Query: 1928 TWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTI 1987
LLEAQA TG ++ P T QKLS+ +AV G++++++ RL A++A G+ +
Sbjct: 2049 QRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKM 2108
Query: 1988 PLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQ 2047
+A++++ + R LE Q TGG++DP+ H R+ E A R+G + + D
Sbjct: 2109 SAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDT 2168
Query: 2048 KHMRKRFVDPNTQEKVSYRELQERCRPQEDTG 2079
K P T+ K+SY++ R ++ TG
Sbjct: 2169 SSYAKILTCPKTKLKISYKDAINRSMVEDITG 2200
Score = 372 bits (955), Expect = e-102
Identities = 287/963 (29%), Positives = 449/963 (46%), Gaps = 149/963 (15%)
Query: 853 RYRQREVTLGQVAKLLEAETQRQAD-------IMLPALRSRVTVHQLLEAGIIDQQLLDQ 905
RY++ L Q ETQ + + ++ LR +VT QL E +ID+ LD+
Sbjct: 1335 RYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQLYECQLIDKTTLDK 1394
Query: 906 VLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLE 965
+L G S E + ++ +L G G++ G P ++ SL +A R+KL+ P + LLE
Sbjct: 1395 LLKGKKSVEEVA--SEIQPFLRGAGSIAGASASPK-EKYSLVEAKRKKLISPESTVMLLE 1451
Query: 966 AQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQA 1025
AQAATG I+DPH E L+VD A+ R ++ + ++ AE AI GF DPFSGK VSV +A
Sbjct: 1452 AQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEA 1511
Query: 1026 MKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALS---SSSE 1082
+KK LI E RLLEAQ+A+GG++DP + LP VA+ RG +D+++ +L+ S +
Sbjct: 1512 IKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQK 1571
Query: 1083 TFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGT 1142
F P + + SY QL E C + +GL LL VQ+ + G +
Sbjct: 1572 NFVDPVTKKKVSYVQLKERCRIEPHTGLLLL-------------SVQKRSMSFQGIRQPV 1618
Query: 1143 SLWDLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGE 1202
++ +L+ S R + +++ G+ + ++ ++ ++Q + +
Sbjct: 1619 TVTELVDSGIL----RPSTVNELESGQISYDEVGERIKDFLQGSSCI------------- 1661
Query: 1203 VPAVWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASI 1262
AGI + T + L I
Sbjct: 1662 --------AGIYNETTKQKL--------------------------------------GI 1675
Query: 1263 AQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAER 1322
+A++ GL+ G LLEAQ A+GF+VDP++N RL VE+A K GLVG E E+L AER
Sbjct: 1676 YEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAER 1735
Query: 1323 AAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRL 1382
A GY DP + +SL+QAM K L+ + G+ LL+ Q+ATGG++DP LP A +
Sbjct: 1736 AVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKR 1795
Query: 1383 GLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEV 1442
G + + S++L+ D K FFDP+ + +TY QL+ERC+ D ETGL LLPL + +V
Sbjct: 1796 GYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPL-KEKKKQV 1854
Query: 1443 DDHTAVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVAL-CRSGRAAALRQV 1501
LR +V V +S+ + + + +EL C
Sbjct: 1855 QTSQKNTLRKRRV-VIVDPETNKEMSVQEAYKKGLIDYETFKELCEQECEWEEITITGSD 1913
Query: 1502 VSAVTALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMD 1561
S LV+ R Q +D L+ RK D+ G+ ++ + A+M
Sbjct: 1914 GSTRVVLVD-----------RKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQFADMI 1962
Query: 1562 SVKR----------------------------------------------SLEGGNFIAG 1575
S+K +LE + IA
Sbjct: 1963 SLKNGVGTSSSMGSGVSDDVFSSSRHESVSKISTISSVRNLTIRSSSFSDTLEESSPIAA 2022
Query: 1576 VLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFKAGMFG 1635
+ E++SI E + R I+ T LLEAQA TG II P +KL++++A G+
Sbjct: 2023 IFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVID 2082
Query: 1636 KETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGIIDPVH 1695
++ +L A++A G+ +++S +A+++ + E G R LE Q TGG++DP
Sbjct: 2083 QDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEV 2142
Query: 1696 SHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLY 1755
R+ + A R G+ D + L D S K P T ++Y + R + + TGL
Sbjct: 2143 HGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLR 2202
Query: 1756 LLQ 1758
LL+
Sbjct: 2203 LLE 2205
Score = 370 bits (950), Expect = e-101
Identities = 287/898 (31%), Positives = 439/898 (48%), Gaps = 113/898 (12%)
Query: 314 TALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGS 373
TA+ L E Q T +D + + V+E V+ E+ L A P
Sbjct: 1377 TAMQLYECQLIDKTTLDKLLKGKKSVEE------VASEIQPFLRGAGSIAGASASP--KE 1428
Query: 374 QIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLS 433
+ L +A +K L+ + LL+AQ ATGG++ P R +L +++A+ +D D ++Q+
Sbjct: 1429 KYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIY 1488
Query: 434 QAGS----FSDGTHGG-LRYEQLLALCVTDPETGLAFLPLSGGPRGG-EPQGPPFIKYST 487
A F D G + + + + D ETG+ L G +P F+
Sbjct: 1489 AAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDV 1548
Query: 488 RQALSTATATV--SVGKFRGRPVSLWELLFSEAISSEQ---RAMLAQQYQEGTLSVEKLA 542
A + S+ R + + + + +S Q R + LSV+K +
Sbjct: 1549 ALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRS 1608
Query: 543 AELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASA 602
++F G+R VT EL+ + I+ LE GQ + +VG
Sbjct: 1609 ---------------MSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGE--RI 1651
Query: 603 QRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGH 662
+ +LQG+ CIAG+ ++++L IYEA GL+RPGTAL LLEAQAATGFI+DP +N
Sbjct: 1652 KDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRL 1711
Query: 663 SVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEA 722
VEEA + ++G + KLLSAERAVTGY DP TG ISLFQAM K LI + HGIRLLEA
Sbjct: 1712 PVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEA 1771
Query: 723 QIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLL 782
QIATGG+IDP SHR+PVD+AY+RGYF++ L+ IL DPSDDTKGFFDPNT ENLTYLQL
Sbjct: 1772 QIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLK 1831
Query: 783 ERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSV---KYGRFQGQRVSAWELINS 839
ERC++D ETGL LLPL + + S + ++ V Q LI+
Sbjct: 1832 ERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDY 1891
Query: 840 EYFSEGRRRQLLRRYRQREVTL-----GQVAKLLEAETQRQADIMLPALRSRVTVHQLLE 894
E F E ++ E+T+ L++ +T Q DI ++
Sbjct: 1892 ETFKELCEQEC----EWEEITITGSDGSTRVVLVDRKTGSQYDI-----------QDAID 1936
Query: 895 AGIIDQQLLDQVLAGTIS----PEALLLMDGV-------------------RRYLCGLGA 931
G++D++ DQ +G++S + + L +GV + +
Sbjct: 1937 KGLVDRKFFDQYRSGSLSLTQFADMISLKNGVGTSSSMGSGVSDDVFSSSRHESVSKIST 1996
Query: 932 VGGVRLL-----------------------PSGQRLSLYQAMRQKLLGPRVALALLEAQA 968
+ VR L + +++S+ + + + ++ LLEAQA
Sbjct: 1997 ISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQA 2056
Query: 969 ATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKK 1028
TG I+ P + + LS+ +AV +GV+ ++ RLK A+ A GF K++S +A+K+
Sbjct: 2057 CTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKE 2116
Query: 1029 GLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETAL---SSSSETFP 1085
+P+E R LE Q TGG++DP H + AI++G++D L SS ++
Sbjct: 2117 KWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILT 2176
Query: 1086 TPDGQGRTSYAQLLEECPRDETSGLHLLPLPE-SAPALPTEEQVQRSLQAVPGAKDGT 1142
P + + SY + ++ +GL LL S+ LP+ ++ + PG++ G+
Sbjct: 2177 CPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPS----PYNMSSAPGSRSGS 2230
Score = 345 bits (885), Expect = 7e-94
Identities = 253/814 (31%), Positives = 406/814 (49%), Gaps = 68/814 (8%)
Query: 40 ARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKAL 99
A SIAG + S+ A + L+ LLEAQAATGG++D R + L V A+
Sbjct: 1416 AGSIAGASASPK-EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAI 1474
Query: 100 QQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGG 159
+ L+ + ++++ AAE+A TG+ DP+ G+ +++ +AI K ++DR G LE Q+A+GG
Sbjct: 1475 ARDLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGG 1534
Query: 160 LVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCV 219
+VDP V + + A +GL+DR+ + L++ P F++P T ++++Y QL ERC
Sbjct: 1535 VVDPVNSVFLPKDVALARGLIDRDLYRSLND--PRDSQKNFVDPVTKKKVSYVQLKERCR 1592
Query: 220 RAPGSGLALLPLK---ITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAE 276
P +GL LL ++ ++F+ + V+ EL++ GIL V L G+++ +V R
Sbjct: 1593 IEPHTGLLLLSVQKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGER-- 1650
Query: 277 VRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQR 336
++ +L+G+ +AG+ K ++A L+ GTAL LLEAQAAT +VDP++ R
Sbjct: 1651 IKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLR 1710
Query: 337 LWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLD 396
L V+EA + GLV E E+LL AE+AVTG++DP +G+ I LFQAM K L+++ +RLL+
Sbjct: 1711 LPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLE 1770
Query: 397 AQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLSQ-----AGSFSDGTHGGLRYEQL 451
AQ+ATGG++ P RLP++ A + G +E+ LS G F T L Y QL
Sbjct: 1771 AQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQL 1830
Query: 452 LALCVTDPETGLAFLPLSGGPRGGEPQGPPFIK--------------YSTRQALSTATAT 497
C+ D ETGL LPL + + ++ S ++A
Sbjct: 1831 KERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLID 1890
Query: 498 VSVGKFRGRPVSLWELLFSEAISSEQRAMLA------------------------QQYQE 533
K WE + R +L QY+
Sbjct: 1891 YETFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRS 1950
Query: 534 GTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATA 593
G+LS+ + A +S L+ T+ SG+ D ++ +E + +T
Sbjct: 1951 GSLSLTQFADMIS--LKNGVGTSSSMGSGVSD----------DVFSSSRHESVSK-ISTI 1997
Query: 594 KDVGSL----ASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAA 649
V +L +S L+ + IA + + E++SI E +G++ T LLEAQA
Sbjct: 1998 SSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQAC 2057
Query: 650 TGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKG 709
TG II P + S+++A+ VI D+ +L A++A G+ +++S +A+++
Sbjct: 2058 TGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEK 2117
Query: 710 LIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFD 769
+ E G R LE Q TGG++DP R+ + A R+G+ D L D S K
Sbjct: 2118 WLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTC 2177
Query: 770 PNTHENLTYLQLLERCVRDPETGLYLLPLSSTQS 803
P T ++Y + R + + TGL LL +S S
Sbjct: 2178 PKTKLKISYKDAINRSMVEDITGLRLLEAASVSS 2211
Score = 330 bits (847), Expect = 2e-89
Identities = 215/519 (41%), Positives = 294/519 (56%), Gaps = 34/519 (6%)
Query: 1927 ATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDT 1986
A L E Q LD + K SV+E V E++ L A A P +
Sbjct: 1378 AMQLYECQLIDKTTLDKLLKGKKSVEE------VASEIQPFLRGAGSIAGASASPK--EK 1429
Query: 1987 IPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISD 2046
L +A +K+LI + LLE Q ATGG+IDP + +L +++A R + D I
Sbjct: 1430 YSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYA 1489
Query: 2047 QKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALEAE 2106
+ F DP + + VS E ++ +TG L A S + D +
Sbjct: 1490 AEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIA---SGGVVDPVNSVFLPK 1546
Query: 2107 QVEITVGR-----FRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILEL 2161
V + G +R + N +KK+ V++ R ++ L+L
Sbjct: 1547 DVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKE---RCRIEPHTGLLLLS 1603
Query: 2162 IEKQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLE 2221
++K+ S FQGIR+ +T +EL+ S I+ + +LE+G+ + E+ E R+K +L+
Sbjct: 1604 VQKRSMS-----FQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGE--RIKDFLQ 1656
Query: 2222 GTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRL 2281
G+SCIAG+ Q K+ IY+AM G++RPGTAL LLEAQAATGF++DPV NLRL
Sbjct: 1657 GSSCIAGIYNETTKQ-----KLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRL 1711
Query: 2282 SVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEA 2341
VEE G+VG E +EKLLSAERAVTGY DP TG ISLFQAM K+LI + HGIRLLEA
Sbjct: 1712 PVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEA 1771
Query: 2342 QIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLL 2401
QIATGG+IDP SHR+PVD+AY+RGYF+EE++ +L+DPSDDTKGFFDPNT ENLTY+QL
Sbjct: 1772 QIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLK 1831
Query: 2402 RRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARV 2440
RC+ D +TGL +L L + Q+ + LR RV
Sbjct: 1832 ERCIKDEETGLCLLPLKEKKK---QVQTSQKNTLRKRRV 1867
Score = 319 bits (818), Expect = 4e-86
Identities = 248/865 (28%), Positives = 410/865 (47%), Gaps = 90/865 (10%)
Query: 1621 RKLTVEEAFKAGMFGKETYVKLLSAERAV---TGYTDPYTG-------------QQISLF 1664
+K+T + ++ + K T KLL +++V P+ ++ SL
Sbjct: 1374 KKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGSIAGASASPKEKYSLV 1433
Query: 1665 QAMQKDLIVREHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDD 1724
+A +K LI E + LLEAQ ATGGIIDP + ++ VD A D + + +
Sbjct: 1434 EAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKA 1493
Query: 1725 TKGFFDPNTHENLTYLQLLERCVEDPETGLYLL--QIIKKGE----NYVYINE--ATRHV 1776
GF DP + + ++ + +++ + D ETG+ LL QI G N V++ + A
Sbjct: 1494 ITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARG 1553
Query: 1777 LQSRTAKMRVGRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIE 1836
L R + D +F D ++ + + +E + +E ++ +++
Sbjct: 1554 LIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCR--------IEPHTGLLLLSVQ 1605
Query: 1837 ETETQNQGIKVAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGS 1896
+ QGI R VT +L +S ++ T++ L G+ + E +K +L+GS
Sbjct: 1606 KRSMSFQGI-----RQPVTVTELVDSGILRPSTVNELESGQISYDEVG--ERIKDFLQGS 1658
Query: 1897 DCIAGVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVD 1956
CIAG+ +T++ + ++EA + L+ A LLEAQAATGF++DP + +L V+EA
Sbjct: 1659 SCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYK 1718
Query: 1957 VGLVNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGV 2016
GLV E +E+LL AERA TGY DP TG+ I LFQAM K+LIEK +RLLE Q+ATGG+
Sbjct: 1719 RGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGI 1778
Query: 2017 IDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQE 2076
IDP+ HRLP++ AY+RG ++++ ++SD K F DPNT+E ++Y +L+ERC E
Sbjct: 1779 IDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDE 1838
Query: 2077 DTGWVLFPVNKAARDSEH-------------IDDETRRAL-------------------- 2103
+TG L P+ + + + +D ET + +
Sbjct: 1839 ETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELC 1898
Query: 2104 --EAEQVEITVGRFRGQKPTLWA--LLNSEYVTEE--KKLQLVRMYRTHTRRALQTVAQL 2157
E E EIT+ G + S+Y ++ K + R + R ++ Q
Sbjct: 1899 EQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQF 1958
Query: 2158 ILELIEKQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVK 2217
+ K G+ + +S E + + T S +
Sbjct: 1959 ADMISLKNGVGTSSSMGSGVSDDVFSSS-------RHESVSKISTISSVRNLTIRSSSFS 2011
Query: 2218 RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVR 2277
LE +S IA + EK+SI + + +G++ T LLEAQA TG +I P
Sbjct: 2012 DTLEESSPIAAIF-----DTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTT 2066
Query: 2278 NLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIR 2337
+LS+++ V GV+ ++ +L A++A G+ +++S +A+++ + E G R
Sbjct: 2067 GQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQR 2126
Query: 2338 LLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTY 2397
LE Q TGG++DP R+ + A R+G+ D + L D S K P T ++Y
Sbjct: 2127 FLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISY 2186
Query: 2398 VQLLRRCVPDPDTGLYMLQLAGRGS 2422
+ R + + TGL +L+ A S
Sbjct: 2187 KDAINRSMVEDITGLRLLEAASVSS 2211
Score = 296 bits (758), Expect = 4e-79
Identities = 157/269 (58%), Positives = 197/269 (73%), Gaps = 10/269 (3%)
Query: 2706 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 2765
+SF+G+R+ V+ +EL SGIL P T+ +L G + EV E +K +L+G+SCIAG+
Sbjct: 1609 MSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGER--IKDFLQGSSCIAGIYN 1666
Query: 2766 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 2825
Q K+ IY+AM G++RPGTAL LLEAQAATGF++DPV NLRL VEEA G+
Sbjct: 1667 ETTKQ-----KLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGL 1721
Query: 2826 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 2885
VG E +EKLLSAERAVTGY DP TG ISLFQAM K+LI + HGIRLLEAQIATGG+IDP
Sbjct: 1722 VGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDP 1781
Query: 2886 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTG 2945
SHR+PVD+AY+RGYF+EE++ +L+DPSDDTKGFFDPNT ENLTY+QL RC+ D +TG
Sbjct: 1782 KESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETG 1841
Query: 2946 LYMLQLAGRGSAVHQLSEELRCALRDARV 2974
L +L L + Q+ + LR RV
Sbjct: 1842 LCLLPLKEKKK---QVQTSQKNTLRKRRV 1867
Score = 296 bits (758), Expect = 4e-79
Identities = 157/269 (58%), Positives = 197/269 (73%), Gaps = 10/269 (3%)
Query: 3240 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 3299
+SF+G+R+ V+ +EL SGIL P T+ +L G + EV E +K +L+G+SCIAG+
Sbjct: 1609 MSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGER--IKDFLQGSSCIAGIYN 1666
Query: 3300 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 3359
Q K+ IY+AM G++RPGTAL LLEAQAATGF++DPV NLRL VEEA G+
Sbjct: 1667 ETTKQ-----KLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGL 1721
Query: 3360 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 3419
VG E +EKLLSAERAVTGY DP TG ISLFQAM K+LI + HGIRLLEAQIATGG+IDP
Sbjct: 1722 VGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDP 1781
Query: 3420 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTG 3479
SHR+PVD+AY+RGYF+EE++ +L+DPSDDTKGFFDPNT ENLTY+QL RC+ D +TG
Sbjct: 1782 KESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETG 1841
Query: 3480 LYMLQLAGRGSAVHQLSEELRCALRDARV 3508
L +L L + Q+ + LR RV
Sbjct: 1842 LCLLPLKEKKK---QVQTSQKNTLRKRRV 1867
Score = 296 bits (758), Expect = 4e-79
Identities = 157/269 (58%), Positives = 197/269 (73%), Gaps = 10/269 (3%)
Query: 3774 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 3833
+SF+G+R+ V+ +EL SGIL P T+ +L G + EV E +K +L+G+SCIAG+
Sbjct: 1609 MSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGER--IKDFLQGSSCIAGIYN 1666
Query: 3834 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 3893
Q K+ IY+AM G++RPGTAL LLEAQAATGF++DPV NLRL VEEA G+
Sbjct: 1667 ETTKQ-----KLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGL 1721
Query: 3894 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 3953
VG E +EKLLSAERAVTGY DP TG ISLFQAM K+LI + HGIRLLEAQIATGG+IDP
Sbjct: 1722 VGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDP 1781
Query: 3954 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTG 4013
SHR+PVD+AY+RGYF+EE++ +L+DPSDDTKGFFDPNT ENLTY+QL RC+ D +TG
Sbjct: 1782 KESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETG 1841
Query: 4014 LYMLQLAGRGSAVHQLSEELRCALRDARV 4042
L +L L + Q+ + LR RV
Sbjct: 1842 LCLLPLKEKKK---QVQTSQKNTLRKRRV 1867
Score = 296 bits (758), Expect = 4e-79
Identities = 157/269 (58%), Positives = 197/269 (73%), Gaps = 10/269 (3%)
Query: 4308 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 4367
+SF+G+R+ V+ +EL SGIL P T+ +L G + EV E +K +L+G+SCIAG+
Sbjct: 1609 MSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGER--IKDFLQGSSCIAGIYN 1666
Query: 4368 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 4427
Q K+ IY+AM G++RPGTAL LLEAQAATGF++DPV NLRL VEEA G+
Sbjct: 1667 ETTKQ-----KLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGL 1721
Query: 4428 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 4487
VG E +EKLLSAERAVTGY DP TG ISLFQAM K+LI + HGIRLLEAQIATGG+IDP
Sbjct: 1722 VGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDP 1781
Query: 4488 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTG 4547
SHR+PVD+AY+RGYF+EE++ +L+DPSDDTKGFFDPNT ENLTY+QL RC+ D +TG
Sbjct: 1782 KESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETG 1841
Query: 4548 LYMLQLAGRGSAVHQLSEELRCALRDARV 4576
L +L L + Q+ + LR RV
Sbjct: 1842 LCLLPLKEKKK---QVQTSQKNTLRKRRV 1867
Score = 293 bits (750), Expect = 3e-78
Identities = 153/246 (62%), Positives = 187/246 (76%), Gaps = 7/246 (2%)
Query: 4842 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 4901
+SF+G+R+ V+ +EL SGIL P T+ +L G + EV E +K +L+G+SCIAG+
Sbjct: 1609 MSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGER--IKDFLQGSSCIAGIYN 1666
Query: 4902 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 4961
Q K+ IY+AM G++RPGTAL LLEAQAATGF++DPV NLRL VEEA G+
Sbjct: 1667 ETTKQ-----KLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGL 1721
Query: 4962 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 5021
VG E +EKLLSAERAVTGY DP TG ISLFQAM K+LI + HGIRLLEAQIATGG+IDP
Sbjct: 1722 VGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDP 1781
Query: 5022 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETG 5081
SHR+PVD+AY+RGYF+EE++ +L+DPSDDTKGFFDPNT ENLTYLQL +R D ETG
Sbjct: 1782 KESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETG 1841
Query: 5082 LLFLSL 5087
L L L
Sbjct: 1842 LCLLPL 1847
Score = 288 bits (737), Expect = 1e-76
Identities = 246/882 (27%), Positives = 409/882 (46%), Gaps = 70/882 (7%)
Query: 1521 FRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLEGGNFIAGVLIQG 1580
F GLRK+V+A L+ QLI + TLD+L +G +V+EVA ++ L G IAG
Sbjct: 1369 FDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGASAS- 1425
Query: 1581 TQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFKAGMFGKETYV 1640
+E+ S+ EA R+ ++ P + ++LLEAQAATG IIDP N KLTV+ A + +
Sbjct: 1426 PKEKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQ 1485
Query: 1641 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGIIDPVHSHRVP 1700
++ +AE+A+TG+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GG++DPV+S +P
Sbjct: 1486 QIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLP 1545
Query: 1701 VDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLYLLQII 1760
DVA G D ++ R L DP D K F DP T + ++Y+QL ERC +P TGL LL +
Sbjct: 1546 KDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQ 1605
Query: 1761 KKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQ 1820
K+ ++ I + + T + G V+ L S + D E I+++
Sbjct: 1606 KRSMSFQGIRQPV-----TVTELVDSGILRPSTVNE---LESGQISYDEVGERIKDFLQG 1657
Query: 1821 SGGLEKLLEIITTTIEETETQNQGIKVAAIRGEV---TAADLFNSR-----VIDQKTLHT 1872
S I ET Q GI A G V TA +L ++ ++D +
Sbjct: 1658 SS-------CIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLR 1710
Query: 1873 LRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFATWLLE 1932
L V + L +E + L + G P T ++SL +A KELI LLE
Sbjct: 1711 LPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLE 1770
Query: 1933 AQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTIPLFQA 1992
AQ ATG ++DP +L VD A G NEEL E L G+ DP T + + Q
Sbjct: 1771 AQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQL 1830
Query: 1993 MQKQLIEKAEALRLLEV-----QVATGG----------VIDPQHHHRLPLETAYRRGCLH 2037
++ + ++ L LL + QV T ++DP+ + + ++ AY++G +
Sbjct: 1831 KERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLID 1890
Query: 2038 KDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDD 2097
+ + + +Q+ + + + + Q D + ++K D + D
Sbjct: 1891 YETFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQYD---IQDAIDKGLVDRKFFDQ 1947
Query: 2098 ETRRALEAEQVE--ITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVA 2155
+L Q I++ G ++ + ++ + + + + ++ + R L +
Sbjct: 1948 YRSGSLSLTQFADMISLKNGVGTSSSMGSGVSDDVFSSSRHESVSKISTISSVRNLTIRS 2007
Query: 2156 QLILELIEKQ---------ETSNKHLWFQGIRR----QITASELLSSAIITEEML----- 2197
+ +E+ E K +GI R IT LL + T ++
Sbjct: 2008 SSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTG 2067
Query: 2198 QDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPG 2257
Q L + +Q +++ D R G + ++KMS +A+ + L
Sbjct: 2068 QKLSLQDAVSQGVIDQDMATRLKPAQKAFIGF-----EGVKGKKKMSAAEAVKEKWLPYE 2122
Query: 2258 TALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQ 2317
LE Q TG ++DP + R+S EE + G + ++L T P T
Sbjct: 2123 AGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKL 2182
Query: 2318 QISLFQAMQKDLIVREHGIRLLE-AQIATGGVIDPVHSHRVP 2358
+IS A+ + ++ G+RLLE A +++ G+ P + P
Sbjct: 2183 KISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAP 2224
Score = 235 bits (600), Expect = 7e-61
Identities = 175/566 (30%), Positives = 285/566 (50%), Gaps = 63/566 (11%)
Query: 544 ELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASAQ 603
E E T+++ F GLR VT +L + ++ID+ ++L G+ + ++V S Q
Sbjct: 1353 ETQTECEWTVDTSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQ 1410
Query: 604 RYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHS 663
+L+G G IAG +E+ S+ EA+ K L+ P + ++LLEAQAATG IIDP N+ +
Sbjct: 1411 PFLRGAGSIAGASA-SPKEKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLT 1469
Query: 664 VEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQ 723
V+ A+ +I D ++ +AE+A+TG+ DP++G+ +S+ +A++K LI RE G+RLLEAQ
Sbjct: 1470 VDSAIARDLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQ 1529
Query: 724 IATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLE 783
IA+GGV+DPV+S +P DVA RG D+ L L DP D K F DP T + ++Y+QL E
Sbjct: 1530 IASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKE 1589
Query: 784 RCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFS 843
RC +P TGL LL + +FQ + Q V+ EL++S
Sbjct: 1590 RCRIEPHTGLLLLSVQK---------RSMSFQGI----------RQPVTVTELVDSGIL- 1629
Query: 844 EGRRRQLLRRYRQREVTLGQVAKLLEAETQRQ---ADIMLPALRSRVTVHQLLEAGII-- 898
R + +++ +V + ++ Q A I + ++ +++ ++ G++
Sbjct: 1630 ---RPSTVNELESGQISYDEVGERIKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRP 1686
Query: 899 -------DQQLLDQVLAGTISPEALLLMDGVRRYLCGL----------GAVGGVRLLPSG 941
+ Q + +S L + + +R L G+ AV G +G
Sbjct: 1687 GTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETG 1746
Query: 942 QRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRL 1001
+SL+QAM ++L+ + LLEAQ ATG I+DP L VD A +RG EL L
Sbjct: 1747 NIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEIL 1806
Query: 1002 KRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLL-----EAQVATGG-------- 1048
GF DP + + ++ Q ++ + E LL + QV T
Sbjct: 1807 SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRR 1866
Query: 1049 --IIDPTSHHHLPMPVAIQRGYVDQE 1072
I+DP ++ + + A ++G +D E
Sbjct: 1867 VVIVDPETNKEMSVQEAYKKGLIDYE 1892
Score = 228 bits (581), Expect = 1e-58
Identities = 174/594 (29%), Positives = 297/594 (50%), Gaps = 37/594 (6%)
Query: 1806 TEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQ------NQGIKVAAIRGEVTAADL 1859
T + + +L E ++KL + + ET+T+ + +R +VTA L
Sbjct: 1322 TRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQL 1381
Query: 1860 FNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRK 1919
+ ++ID+ TL L G+ + +++ ++P+L G+ IAG + S +E SL EA RK
Sbjct: 1382 YECQLIDKTTLDKLLKGKKSVEEVASE--IQPFLRGAGSIAGASA-SPKEKYSLVEAKRK 1438
Query: 1920 ELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYR 1979
+LI LLEAQAATG ++DP +KL+VD A+ L++ + R+++ AE+A TG+
Sbjct: 1439 KLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAITGFD 1498
Query: 1980 DPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKD 2039
DP +G T+ + +A++K LI++ +RLLE Q+A+GGV+DP + LP + A RG + +D
Sbjct: 1499 DPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARGLIDRD 1558
Query: 2040 IYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDET 2099
+Y ++D + +K FVDP T++KVSY +L+ERCR + TG +L V K + + I
Sbjct: 1559 LYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRSMSFQGI---R 1615
Query: 2100 RRALEAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLIL 2159
+ E V+ + R P+ L S ++ ++ + ++ + + +A +
Sbjct: 1616 QPVTVTELVDSGILR-----PSTVNELESGQISYDEVGERIKDF----LQGSSCIAGIYN 1666
Query: 2160 ELIEKQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRY 2219
E KQ+ G+ R TA ELL + T ++ + R +E + V
Sbjct: 1667 E-TTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIE 1725
Query: 2220 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 2279
+ A V + P +S++QAM K ++ G + LLEAQ ATG +IDP +
Sbjct: 1726 FKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESH 1785
Query: 2280 RLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 2339
RL V+ G E+ E L G+ DP T + ++ Q ++ + E G+ LL
Sbjct: 1786 RLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLL 1845
Query: 2340 -----EAQIATGG----------VIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 2378
+ Q+ T ++DP + + V AY++G D E + L +
Sbjct: 1846 PLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCE 1899
Score = 213 bits (543), Expect = 3e-54
Identities = 234/890 (26%), Positives = 391/890 (43%), Gaps = 93/890 (10%)
Query: 232 KITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVV 291
K+ F + V+A +L E ++D+ + L +G+ + +V++ E++ +L G GS+AG
Sbjct: 1366 KLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGAS 1423
Query: 292 LLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPE 351
P+ K S +A + L+ + + LLEAQAAT ++DP ++L VD A+ L+ +
Sbjct: 1424 ASPK-EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFD 1482
Query: 352 LHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRL 411
+Q+ AE+A+TG DPFSG + + +A+KK L+DR +RLL+AQ+A+GG+V P +
Sbjct: 1483 DRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSV 1542
Query: 412 RLPLEAALRCGCLDEDTQRQL-----SQAGSFSDGTHGGLRYEQLLALCVTDPETGLAFL 466
LP + AL G +D D R L SQ T + Y QL C +P TGL L
Sbjct: 1543 FLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGL--L 1600
Query: 467 PLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAM 526
LS R QG RQ + T T V G R V+ E S IS ++
Sbjct: 1601 LLSVQKRSMSFQG-------IRQPV-TVTELVDSGILRPSTVNELE---SGQISYDEVGE 1649
Query: 527 LAQQYQEGTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAE-----IIDQD 581
+ + +G+ + A + T +Q GL T ELL+A+ I+D
Sbjct: 1650 RIKDFLQGSSCI---AGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPV 1706
Query: 582 LYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTAL 641
RL +A + + + ++ L + G P + +S+++A K L+ G +
Sbjct: 1707 SNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI 1766
Query: 642 ILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQIS 701
LLEAQ ATG IIDPK + V+ A + ++ L G+ DP T + ++
Sbjct: 1767 RLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLT 1826
Query: 702 LFQAMQKGLIVREHGIRLL-----EAQIATGG----------VIDPVHSHRVPVDVAYRR 746
Q ++ + E G+ LL + Q+ T ++DP + + V AY++
Sbjct: 1827 YLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKK 1886
Query: 747 GYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSPLV 806
G D L + + + + + T + L++R +TG + LV
Sbjct: 1887 GLIDYETFKELCEQECEWEEITITGS-DGSTRVVLVDR-----KTGSQYDIQDAIDKGLV 1940
Query: 807 D------------SATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQL---- 850
D S TQ A ++S+K G G S ++ + FS R +
Sbjct: 1941 DRKFFDQYRSGSLSLTQFAD---MISLKNG--VGTSSSMGSGVSDDVFSSSRHESVSKIS 1995
Query: 851 -LRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIID----QQLLD- 904
+ R + + LE E+ A I ++++ + +E GI+D Q+LL+
Sbjct: 1996 TISSVRNLTIRSSSFSDTLE-ESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEA 2054
Query: 905 -QVLAGTISP---EALLLMDGV----------RRYLCGLGAVGGVRLLPSGQRLSLYQAM 950
G I P + L L D V R A G + +++S +A+
Sbjct: 2055 QACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAV 2114
Query: 951 RQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAG 1010
++K L LE Q TG ++DP +S +EA+R+G + RL+
Sbjct: 2115 KEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKI 2174
Query: 1011 FRDPFSGKQVSVFQAMKKGLIPWEQAARLLE-AQVATGGIIDPTSHHHLP 1059
P + ++S A+ + ++ RLLE A V++ G+ P + P
Sbjct: 2175 LTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAP 2224
Score = 198 bits (504), Expect = 1e-49
Identities = 105/248 (42%), Positives = 167/248 (67%), Gaps = 8/248 (3%)
Query: 4840 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 4899
SK+ F GLR++V+A +L+ ++ TL L +G K+++EV ++ +L G IAG
Sbjct: 1365 SKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGA 1422
Query: 4900 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 4959
K EK S+ +A K ++ P + ++LLEAQAATG +IDP RN +L+V+ A+A
Sbjct: 1423 SASPK------EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIAR 1476
Query: 4960 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 5019
++ + ++++ +AE+A+TG+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GGV+
Sbjct: 1477 DLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVV 1536
Query: 5020 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPE 5079
DPV+S +P DVA RG D ++ R L DP D K F DP T + ++Y+QL +R ++P
Sbjct: 1537 DPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPH 1596
Query: 5080 TGLLFLSL 5087
TGLL LS+
Sbjct: 1597 TGLLLLSV 1604
Score = 197 bits (501), Expect = 2e-49
Identities = 106/251 (42%), Positives = 166/251 (66%), Gaps = 8/251 (3%)
Query: 2704 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 2763
SK+ F GLR++V+A +L+ ++ TL L +G K+++EV ++ +L G IAG
Sbjct: 1365 SKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGA 1422
Query: 2764 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 2823
K EK S+ +A K ++ P + ++LLEAQAATG +IDP RN +L+V+ A+A
Sbjct: 1423 SASPK------EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIAR 1476
Query: 2824 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 2883
++ + ++++ +AE+A+TG+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GGV+
Sbjct: 1477 DLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVV 1536
Query: 2884 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 2943
DPV+S +P DVA RG D ++ R L DP D K F DP T + ++YVQL RC +P
Sbjct: 1537 DPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPH 1596
Query: 2944 TGLYMLQLAGR 2954
TGL +L + R
Sbjct: 1597 TGLLLLSVQKR 1607
Score = 197 bits (501), Expect = 2e-49
Identities = 106/251 (42%), Positives = 166/251 (66%), Gaps = 8/251 (3%)
Query: 3238 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 3297
SK+ F GLR++V+A +L+ ++ TL L +G K+++EV ++ +L G IAG
Sbjct: 1365 SKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGA 1422
Query: 3298 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 3357
K EK S+ +A K ++ P + ++LLEAQAATG +IDP RN +L+V+ A+A
Sbjct: 1423 SASPK------EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIAR 1476
Query: 3358 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 3417
++ + ++++ +AE+A+TG+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GGV+
Sbjct: 1477 DLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVV 1536
Query: 3418 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 3477
DPV+S +P DVA RG D ++ R L DP D K F DP T + ++YVQL RC +P
Sbjct: 1537 DPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPH 1596
Query: 3478 TGLYMLQLAGR 3488
TGL +L + R
Sbjct: 1597 TGLLLLSVQKR 1607
Score = 197 bits (501), Expect = 2e-49
Identities = 106/251 (42%), Positives = 166/251 (66%), Gaps = 8/251 (3%)
Query: 3772 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 3831
SK+ F GLR++V+A +L+ ++ TL L +G K+++EV ++ +L G IAG
Sbjct: 1365 SKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGA 1422
Query: 3832 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 3891
K EK S+ +A K ++ P + ++LLEAQAATG +IDP RN +L+V+ A+A
Sbjct: 1423 SASPK------EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIAR 1476
Query: 3892 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 3951
++ + ++++ +AE+A+TG+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GGV+
Sbjct: 1477 DLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVV 1536
Query: 3952 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 4011
DPV+S +P DVA RG D ++ R L DP D K F DP T + ++YVQL RC +P
Sbjct: 1537 DPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPH 1596
Query: 4012 TGLYMLQLAGR 4022
TGL +L + R
Sbjct: 1597 TGLLLLSVQKR 1607
Score = 197 bits (501), Expect = 2e-49
Identities = 106/251 (42%), Positives = 166/251 (66%), Gaps = 8/251 (3%)
Query: 4306 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 4365
SK+ F GLR++V+A +L+ ++ TL L +G K+++EV ++ +L G IAG
Sbjct: 1365 SKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGA 1422
Query: 4366 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 4425
K EK S+ +A K ++ P + ++LLEAQAATG +IDP RN +L+V+ A+A
Sbjct: 1423 SASPK------EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIAR 1476
Query: 4426 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 4485
++ + ++++ +AE+A+TG+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GGV+
Sbjct: 1477 DLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVV 1536
Query: 4486 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 4545
DPV+S +P DVA RG D ++ R L DP D K F DP T + ++YVQL RC +P
Sbjct: 1537 DPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPH 1596
Query: 4546 TGLYMLQLAGR 4556
TGL +L + R
Sbjct: 1597 TGLLLLSVQKR 1607
Score = 191 bits (485), Expect = 2e-47
Identities = 120/351 (34%), Positives = 198/351 (56%), Gaps = 28/351 (7%)
Query: 2070 ERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSE 2129
ER + + + + + + + + I++ RR LE E T + ++ S
Sbjct: 1285 EREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRE-TQSQLETER--------SR 1335
Query: 2130 YVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSS 2189
Y E KL+ R Y +H R QT + ++ L F G+R+++TA +L
Sbjct: 1336 YQREIDKLRQ-RPYGSH--RETQTECEWTVD--------TSKLVFDGLRKKVTAMQLYEC 1384
Query: 2190 AIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAM 2249
+I + L L G+ + +E+ + ++ +L G IAG K EK S+ +A
Sbjct: 1385 QLIDKTTLDKLLKGKKSVEEVASE--IQPFLRGAGSIAGASASPK------EKYSLVEAK 1436
Query: 2250 WKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTG 2309
K ++ P + ++LLEAQAATG +IDP RN +L+V+ + ++ + ++++ +AE+A+TG
Sbjct: 1437 RKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAITG 1496
Query: 2310 YTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFD 2369
+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GGV+DPV+S +P DVA RG D
Sbjct: 1497 FDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARGLID 1556
Query: 2370 EEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGR 2420
++ R L DP D K F DP T + ++YVQL RC +P TGL +L + R
Sbjct: 1557 RDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKR 1607
Score = 97.1 bits (240), Expect = 4e-19
Identities = 58/182 (31%), Positives = 99/182 (54%)
Query: 2775 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 2834
EK+SI + + +G++ T LLEAQA TG +I P +LS+++AV+ GV+ ++ +L
Sbjct: 2030 EKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRL 2089
Query: 2835 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 2894
A++A G+ +++S +A+++ + E G R LE Q TGG++DP R+ +
Sbjct: 2090 KPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTE 2149
Query: 2895 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGR 2954
A R+G+ D + L D S K P T ++Y + R + + TGL +L+ A
Sbjct: 2150 EAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASV 2209
Query: 2955 GS 2956
S
Sbjct: 2210 SS 2211
Score = 97.1 bits (240), Expect = 4e-19
Identities = 58/182 (31%), Positives = 99/182 (54%)
Query: 3309 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 3368
EK+SI + + +G++ T LLEAQA TG +I P +LS+++AV+ GV+ ++ +L
Sbjct: 2030 EKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRL 2089
Query: 3369 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 3428
A++A G+ +++S +A+++ + E G R LE Q TGG++DP R+ +
Sbjct: 2090 KPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTE 2149
Query: 3429 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGR 3488
A R+G+ D + L D S K P T ++Y + R + + TGL +L+ A
Sbjct: 2150 EAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASV 2209
Query: 3489 GS 3490
S
Sbjct: 2210 SS 2211
Score = 97.1 bits (240), Expect = 4e-19
Identities = 58/182 (31%), Positives = 99/182 (54%)
Query: 3843 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 3902
EK+SI + + +G++ T LLEAQA TG +I P +LS+++AV+ GV+ ++ +L
Sbjct: 2030 EKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRL 2089
Query: 3903 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 3962
A++A G+ +++S +A+++ + E G R LE Q TGG++DP R+ +
Sbjct: 2090 KPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTE 2149
Query: 3963 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGR 4022
A R+G+ D + L D S K P T ++Y + R + + TGL +L+ A
Sbjct: 2150 EAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASV 2209
Query: 4023 GS 4024
S
Sbjct: 2210 SS 2211
Score = 97.1 bits (240), Expect = 4e-19
Identities = 58/182 (31%), Positives = 99/182 (54%)
Query: 4377 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 4436
EK+SI + + +G++ T LLEAQA TG +I P +LS+++AV+ GV+ ++ +L
Sbjct: 2030 EKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRL 2089
Query: 4437 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 4496
A++A G+ +++S +A+++ + E G R LE Q TGG++DP R+ +
Sbjct: 2090 KPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTE 2149
Query: 4497 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGR 4556
A R+G+ D + L D S K P T ++Y + R + + TGL +L+ A
Sbjct: 2150 EAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASV 2209
Query: 4557 GS 4558
S
Sbjct: 2210 SS 2211
Score = 95.9 bits (237), Expect = 9e-19
Identities = 56/179 (31%), Positives = 97/179 (54%), Gaps = 2/179 (1%)
Query: 1259 KASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLG 1318
K SI + + G++ + GQRLLEAQ +G ++ P Q+LS++DAV G++ ++++ +L
Sbjct: 2031 KISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLK 2090
Query: 1319 QAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDP-VHGVHLPQA 1377
A++A G+ + +S +A+++ +P G L+ Q TGG+VDP VHG +
Sbjct: 2091 PAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHG-RISTE 2149
Query: 1378 AACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPS 1436
A R G +D + +Q L K P + +++Y+ R + + TGL LL S
Sbjct: 2150 EAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAAS 2208
Score = 95.1 bits (235), Expect = 2e-18
Identities = 56/175 (32%), Positives = 96/175 (54%)
Query: 4911 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 4970
EK+SI + + +G++ T LLEAQA TG +I P +LS+++AV+ GV+ ++ +L
Sbjct: 2030 EKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRL 2089
Query: 4971 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 5030
A++A G+ +++S +A+++ + E G R LE Q TGG++DP R+ +
Sbjct: 2090 KPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTE 2149
Query: 5031 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFL 5085
A R+G+ D + L D S K P T ++Y + R+ ++ TGL L
Sbjct: 2150 EAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLL 2204
Score = 89.4 bits (220), Expect = 9e-17
Identities = 55/191 (28%), Positives = 100/191 (52%), Gaps = 2/191 (1%)
Query: 39 QARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKA 98
++ IA ++ + + S+ +E+G++ + GQ LLEAQA TGG++ GQ L + A
Sbjct: 2016 ESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDA 2075
Query: 99 LQQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATG 158
+ QG++ ++ +L A++A G+ G +K++ +A+ ++ + GQ +LE Q TG
Sbjct: 2076 VSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTG 2135
Query: 159 GLVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERC 218
GLVDP ++ E A +G +D +L + L P T +++Y + R
Sbjct: 2136 GLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTC--PKTKLKISYKDAINRS 2193
Query: 219 VRAPGSGLALL 229
+ +GL LL
Sbjct: 2194 MVEDITGLRLL 2204
Score = 70.9 bits (172), Expect = 3e-11
Identities = 42/170 (24%), Positives = 82/170 (48%), Gaps = 7/170 (4%)
Query: 4920 WKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTG 4979
++G+ +P T L+++ ++ + + ++S +E GE + L + G
Sbjct: 1611 FQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEV-------GERIKDFLQGSSCIAG 1663
Query: 4980 YTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFD 5039
+ T Q++ +++AM+ L+ + LLEAQ ATG ++DPV + R+PV+ AY+RG
Sbjct: 1664 IYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVG 1723
Query: 5040 EEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSL 5089
E L G+ DP T ++ Q + + ++ G+ L +
Sbjct: 1724 IEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQI 1773
Score = 69.7 bits (169), Expect = 7e-11
Identities = 51/171 (29%), Positives = 82/171 (47%), Gaps = 8/171 (4%)
Query: 4919 MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVT 4978
++ G+ + TA+ L E Q +D + + SVEE V EIQ L A
Sbjct: 1368 VFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEE------VASEIQPFLRGAGSIAG 1421
Query: 4979 GYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 5038
P ++ SL +A +K LI E + LLEAQ ATGG+IDP + ++ VD A R
Sbjct: 1422 ASASPK--EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI 1479
Query: 5039 DEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSL 5089
D + + + GF DP + + ++ + +++ +D ETG+ L +
Sbjct: 1480 DFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQI 1530
Score = 65.9 bits (159), Expect = 1e-09
Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 15/163 (9%)
Query: 2765 VPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAG 2824
V + P +S++QAM K ++ G + LLEAQ ATG +IDP + RL V+ A G
Sbjct: 1737 VTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRG 1796
Query: 2825 VVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL-----EAQIAT 2879
E+ E L G+ DP T + ++ Q ++ + E G+ LL + Q+ T
Sbjct: 1797 YFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQT 1856
Query: 2880 GG----------VIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 2912
++DP + + V AY++G D E + L +
Sbjct: 1857 SQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCE 1899
Score = 65.9 bits (159), Expect = 1e-09
Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 15/163 (9%)
Query: 3299 VPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAG 3358
V + P +S++QAM K ++ G + LLEAQ ATG +IDP + RL V+ A G
Sbjct: 1737 VTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRG 1796
Query: 3359 VVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL-----EAQIAT 3413
E+ E L G+ DP T + ++ Q ++ + E G+ LL + Q+ T
Sbjct: 1797 YFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQT 1856
Query: 3414 GG----------VIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 3446
++DP + + V AY++G D E + L +
Sbjct: 1857 SQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCE 1899
Score = 65.9 bits (159), Expect = 1e-09
Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 15/163 (9%)
Query: 3833 VPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAG 3892
V + P +S++QAM K ++ G + LLEAQ ATG +IDP + RL V+ A G
Sbjct: 1737 VTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRG 1796
Query: 3893 VVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL-----EAQIAT 3947
E+ E L G+ DP T + ++ Q ++ + E G+ LL + Q+ T
Sbjct: 1797 YFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQT 1856
Query: 3948 GG----------VIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 3980
++DP + + V AY++G D E + L +
Sbjct: 1857 SQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCE 1899
Score = 65.9 bits (159), Expect = 1e-09
Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 15/163 (9%)
Query: 4367 VPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAG 4426
V + P +S++QAM K ++ G + LLEAQ ATG +IDP + RL V+ A G
Sbjct: 1737 VTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRG 1796
Query: 4427 VVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL-----EAQIAT 4481
E+ E L G+ DP T + ++ Q ++ + E G+ LL + Q+ T
Sbjct: 1797 YFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQT 1856
Query: 4482 GG----------VIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 4514
++DP + + V AY++G D E + L +
Sbjct: 1857 SQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCE 1899
Score = 65.9 bits (159), Expect = 1e-09
Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 15/163 (9%)
Query: 4901 VPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAG 4960
V + P +S++QAM K ++ G + LLEAQ ATG +IDP + RL V+ A G
Sbjct: 1737 VTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRG 1796
Query: 4961 VVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL-----EAQIAT 5015
E+ E L G+ DP T + ++ Q ++ + E G+ LL + Q+ T
Sbjct: 1797 YFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQT 1856
Query: 5016 GG----------VIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 5048
++DP + + V AY++G D E + L +
Sbjct: 1857 SQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCE 1899
Score = 62.8 bits (151), Expect = 9e-09
Identities = 43/168 (25%), Positives = 80/168 (47%), Gaps = 8/168 (4%)
Query: 4858 TSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQ 4917
T GI+ P L + +++ + D ++ I G D P + +S+ +
Sbjct: 1456 TGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAITGF-----DDPFSGKTVSVSE 1510
Query: 4918 AMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAV 4977
A+ K ++ T + LLEAQ A+G V+DPV ++ L + A+A G++ ++ L +
Sbjct: 1511 AIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQ 1570
Query: 4978 TGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQ---IATGGVIDPV 5022
+ DP T +++S Q ++ I G+ LL Q ++ G+ PV
Sbjct: 1571 KNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRSMSFQGIRQPV 1618
Score = 55.5 bits (132), Expect = 1e-06
Identities = 53/203 (26%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 2701 ERLSKVSF-----RGLRRQVSASELH-----TSGILGPETLRDLAQGTKTLQEVTEMDSV 2750
E L K+S RG+ ++ L T GI+ P T + L+ Q V + D
Sbjct: 2027 ENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMA 2086
Query: 2751 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 2810
R G + ++KMS +A+ + L LE Q TG ++DP
Sbjct: 2087 TRLKPAQKAFIGF-----EGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPE 2141
Query: 2811 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 2870
+ R+S EEA+ G + G ++L T P T +IS A+ + ++ G+
Sbjct: 2142 VHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGL 2201
Query: 2871 RLLE-AQIATGGVIDPVHSHRVP 2892
RLLE A +++ G+ P + P
Sbjct: 2202 RLLEAASVSSKGLPSPYNMSSAP 2224
Score = 55.5 bits (132), Expect = 1e-06
Identities = 53/203 (26%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 3235 ERLSKVSF-----RGLRRQVSASELH-----TSGILGPETLRDLAQGTKTLQEVTEMDSV 3284
E L K+S RG+ ++ L T GI+ P T + L+ Q V + D
Sbjct: 2027 ENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMA 2086
Query: 3285 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 3344
R G + ++KMS +A+ + L LE Q TG ++DP
Sbjct: 2087 TRLKPAQKAFIGF-----EGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPE 2141
Query: 3345 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 3404
+ R+S EEA+ G + G ++L T P T +IS A+ + ++ G+
Sbjct: 2142 VHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGL 2201
Query: 3405 RLLE-AQIATGGVIDPVHSHRVP 3426
RLLE A +++ G+ P + P
Sbjct: 2202 RLLEAASVSSKGLPSPYNMSSAP 2224
Score = 55.5 bits (132), Expect = 1e-06
Identities = 53/203 (26%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 3769 ERLSKVSF-----RGLRRQVSASELH-----TSGILGPETLRDLAQGTKTLQEVTEMDSV 3818
E L K+S RG+ ++ L T GI+ P T + L+ Q V + D
Sbjct: 2027 ENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMA 2086
Query: 3819 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 3878
R G + ++KMS +A+ + L LE Q TG ++DP
Sbjct: 2087 TRLKPAQKAFIGF-----EGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPE 2141
Query: 3879 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 3938
+ R+S EEA+ G + G ++L T P T +IS A+ + ++ G+
Sbjct: 2142 VHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGL 2201
Query: 3939 RLLE-AQIATGGVIDPVHSHRVP 3960
RLLE A +++ G+ P + P
Sbjct: 2202 RLLEAASVSSKGLPSPYNMSSAP 2224
Score = 55.5 bits (132), Expect = 1e-06
Identities = 53/203 (26%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 4303 ERLSKVSF-----RGLRRQVSASELH-----TSGILGPETLRDLAQGTKTLQEVTEMDSV 4352
E L K+S RG+ ++ L T GI+ P T + L+ Q V + D
Sbjct: 2027 ENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMA 2086
Query: 4353 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 4412
R G + ++KMS +A+ + L LE Q TG ++DP
Sbjct: 2087 TRLKPAQKAFIGF-----EGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPE 2141
Query: 4413 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 4472
+ R+S EEA+ G + G ++L T P T +IS A+ + ++ G+
Sbjct: 2142 VHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGL 2201
Query: 4473 RLLE-AQIATGGVIDPVHSHRVP 4494
RLLE A +++ G+ P + P
Sbjct: 2202 RLLEAASVSSKGLPSPYNMSSAP 2224
Score = 55.5 bits (132), Expect = 1e-06
Identities = 53/203 (26%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 4837 ERLSKVSF-----RGLRRQVSASELH-----TSGILGPETLRDLAQGTKTLQEVTEMDSV 4886
E L K+S RG+ ++ L T GI+ P T + L+ Q V + D
Sbjct: 2027 ENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMA 2086
Query: 4887 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 4946
R G + ++KMS +A+ + L LE Q TG ++DP
Sbjct: 2087 TRLKPAQKAFIGF-----EGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPE 2141
Query: 4947 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 5006
+ R+S EEA+ G + G ++L T P T +IS A+ + ++ G+
Sbjct: 2142 VHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGL 2201
Query: 5007 RLLE-AQIATGGVIDPVHSHRVP 5028
RLLE A +++ G+ P + P
Sbjct: 2202 RLLEAASVSSKGLPSPYNMSSAP 2224
Score = 37.4 bits (85), Expect = 0.38
Identities = 35/150 (23%), Positives = 62/150 (41%), Gaps = 7/150 (4%)
Query: 15 NSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQAL 74
++ Q + + MA L +P ++ G + S A+++ LP GQ
Sbjct: 2074 DAVSQGVIDQDMATRL------KPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRF 2127
Query: 75 LEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLALF 134
LE Q TGGLVD + +A+++G + ++L P K++
Sbjct: 2128 LEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYK 2187
Query: 135 QAIGKEVVDRALGQSWLE-VQLATGGLVDP 163
AI + +V+ G LE +++ GL P
Sbjct: 2188 DAINRSMVEDITGLRLLEAASVSSKGLPSP 2217
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 382 bits (981), Expect = e-105
Identities = 283/872 (32%), Positives = 439/872 (50%), Gaps = 91/872 (10%)
Query: 1263 AQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAER 1322
++ V DGL +L E Q+ +D L + SVE+ V E+ L A
Sbjct: 1964 SKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEE------VASEIQPFLRGAGS 2017
Query: 1323 AAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRL 1382
A P + SL +A K L+ + LL+ Q ATGG++DP L +A
Sbjct: 2018 IAGASASP--KEKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIAR 2075
Query: 1383 GLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEV 1442
L+D Q + A +K F DP + V+ + ++ + D ETG+ LL + V
Sbjct: 2076 DLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVV 2135
Query: 1443 DDHTAVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALR--- 1499
D +V L P +G DL S D ++ V + + ++
Sbjct: 2136 DPVNSVFL-----PKDVALARGLIDR--DLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKE 2188
Query: 1500 --QVVSAVTALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEV 1557
++ L+ + +++ + +F+G+R+ V+ +L + ++ T++EL G + EV
Sbjct: 2189 RCRIEPHTGLLLLSVQKRSM--SFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEV 2246
Query: 1558 AEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDP 1617
E +K L+G + IAG+ + T++++ I EA++ ++RPGTAL LLEAQAATGFI+DP
Sbjct: 2247 GER--IKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDP 2304
Query: 1618 AENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHG 1677
N +L VEEA+K G+ G E KLLSAERAVTGY DP TG ISLFQAM K+LI + HG
Sbjct: 2305 VSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHG 2364
Query: 1678 IRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENL 1737
IRLLEAQIATGGIIDP SHR+PVD+AY+ GYF+EE++ IL+DPSDDTKGFFDPNT ENL
Sbjct: 2365 IRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENL 2424
Query: 1738 TYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSR---------TAKMRVGR 1788
TYLQL ERC++D ETGL LL + +K + + + ++ L+ R +M V
Sbjct: 2425 TYLQLKERCIKDEETGLCLLPLKEKKKQ---VQTSQKNTLRKRRVVIVDPETNKEMSVQE 2481
Query: 1789 -FADQVVSF------------WDLL-------SSPYFTEDRK-----------------R 1811
+ ++ + W+ + S+ DRK R
Sbjct: 2482 AYKKGLIDYETFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDR 2541
Query: 1812 ELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLFNS----RVIDQ 1867
+ +Y + S L + ++I+ G+ ++ G + D+F+S V
Sbjct: 2542 KFFDQYRSGSLSLTQFADMISL--------KNGVGTSSSMGSGVSDDVFSSSRHESVSKI 2593
Query: 1868 KTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFA 1927
T+ ++R + S LE S IA + E +S+ E + ++ +
Sbjct: 2594 STISSVRNLTIRSSSFSDT------LEESSPIAAIFDTENLEKISITEGIERGIVDSITG 2647
Query: 1928 TWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTI 1987
LLEAQA TG ++ P T QKLS+ +AV G++++++ RL A++A G+ +
Sbjct: 2648 QRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKM 2707
Query: 1988 PLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQ 2047
+A++++ + R LE Q TGG++DP+ H R+ E A R+G + + D
Sbjct: 2708 SAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDT 2767
Query: 2048 KHMRKRFVDPNTQEKVSYRELQERCRPQEDTG 2079
K P T+ K+SY++ R ++ TG
Sbjct: 2768 SSYAKILTCPKTKLKISYKDAINRSMVEDITG 2799
Score = 372 bits (955), Expect = e-102
Identities = 287/963 (29%), Positives = 449/963 (46%), Gaps = 149/963 (15%)
Query: 853 RYRQREVTLGQVAKLLEAETQRQAD-------IMLPALRSRVTVHQLLEAGIIDQQLLDQ 905
RY++ L Q ETQ + + ++ LR +VT QL E +ID+ LD+
Sbjct: 1934 RYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQLYECQLIDKTTLDK 1993
Query: 906 VLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLE 965
+L G S E + ++ +L G G++ G P ++ SL +A R+KL+ P + LLE
Sbjct: 1994 LLKGKKSVEEVA--SEIQPFLRGAGSIAGASASPK-EKYSLVEAKRKKLISPESTVMLLE 2050
Query: 966 AQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQA 1025
AQAATG I+DPH E L+VD A+ R ++ + ++ AE AI GF DPFSGK VSV +A
Sbjct: 2051 AQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEA 2110
Query: 1026 MKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALS---SSSE 1082
+KK LI E RLLEAQ+A+GG++DP + LP VA+ RG +D+++ +L+ S +
Sbjct: 2111 IKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQK 2170
Query: 1083 TFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGT 1142
F P + + SY QL E C + +GL LL VQ+ + G +
Sbjct: 2171 NFVDPVTKKKVSYVQLKERCRIEPHTGLLLL-------------SVQKRSMSFQGIRQPV 2217
Query: 1143 SLWDLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGE 1202
++ +L+ S R + +++ G+ + ++ ++ ++Q + +
Sbjct: 2218 TVTELVDSGIL----RPSTVNELESGQISYDEVGERIKDFLQGSSCI------------- 2260
Query: 1203 VPAVWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASI 1262
AGI + T + L I
Sbjct: 2261 --------AGIYNETTKQKL--------------------------------------GI 2274
Query: 1263 AQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAER 1322
+A++ GL+ G LLEAQ A+GF+VDP++N RL VE+A K GLVG E E+L AER
Sbjct: 2275 YEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAER 2334
Query: 1323 AAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRL 1382
A GY DP + +SL+QAM K L+ + G+ LL+ Q+ATGG++DP LP A +
Sbjct: 2335 AVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKR 2394
Query: 1383 GLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEV 1442
G + + S++L+ D K FFDP+ + +TY QL+ERC+ D ETGL LLPL + +V
Sbjct: 2395 GYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPL-KEKKKQV 2453
Query: 1443 DDHTAVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVAL-CRSGRAAALRQV 1501
LR +V V +S+ + + + +EL C
Sbjct: 2454 QTSQKNTLRKRRV-VIVDPETNKEMSVQEAYKKGLIDYETFKELCEQECEWEEITITGSD 2512
Query: 1502 VSAVTALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMD 1561
S LV+ R Q +D L+ RK D+ G+ ++ + A+M
Sbjct: 2513 GSTRVVLVD-----------RKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQFADMI 2561
Query: 1562 SVKR----------------------------------------------SLEGGNFIAG 1575
S+K +LE + IA
Sbjct: 2562 SLKNGVGTSSSMGSGVSDDVFSSSRHESVSKISTISSVRNLTIRSSSFSDTLEESSPIAA 2621
Query: 1576 VLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFKAGMFG 1635
+ E++SI E + R I+ T LLEAQA TG II P +KL++++A G+
Sbjct: 2622 IFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVID 2681
Query: 1636 KETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGIIDPVH 1695
++ +L A++A G+ +++S +A+++ + E G R LE Q TGG++DP
Sbjct: 2682 QDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEV 2741
Query: 1696 SHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLY 1755
R+ + A R G+ D + L D S K P T ++Y + R + + TGL
Sbjct: 2742 HGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLR 2801
Query: 1756 LLQ 1758
LL+
Sbjct: 2802 LLE 2804
Score = 370 bits (950), Expect = e-101
Identities = 287/898 (31%), Positives = 439/898 (48%), Gaps = 113/898 (12%)
Query: 314 TALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGS 373
TA+ L E Q T +D + + V+E V+ E+ L A P
Sbjct: 1976 TAMQLYECQLIDKTTLDKLLKGKKSVEE------VASEIQPFLRGAGSIAGASASP--KE 2027
Query: 374 QIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLS 433
+ L +A +K L+ + LL+AQ ATGG++ P R +L +++A+ +D D ++Q+
Sbjct: 2028 KYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIY 2087
Query: 434 QAGS----FSDGTHGG-LRYEQLLALCVTDPETGLAFLPLSGGPRGG-EPQGPPFIKYST 487
A F D G + + + + D ETG+ L G +P F+
Sbjct: 2088 AAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDV 2147
Query: 488 RQALSTATATV--SVGKFRGRPVSLWELLFSEAISSEQ---RAMLAQQYQEGTLSVEKLA 542
A + S+ R + + + + +S Q R + LSV+K +
Sbjct: 2148 ALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRS 2207
Query: 543 AELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASA 602
++F G+R VT EL+ + I+ LE GQ + +VG
Sbjct: 2208 ---------------MSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGE--RI 2250
Query: 603 QRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGH 662
+ +LQG+ CIAG+ ++++L IYEA GL+RPGTAL LLEAQAATGFI+DP +N
Sbjct: 2251 KDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRL 2310
Query: 663 SVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEA 722
VEEA + ++G + KLLSAERAVTGY DP TG ISLFQAM K LI + HGIRLLEA
Sbjct: 2311 PVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEA 2370
Query: 723 QIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLL 782
QIATGG+IDP SHR+PVD+AY+RGYF++ L+ IL DPSDDTKGFFDPNT ENLTYLQL
Sbjct: 2371 QIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLK 2430
Query: 783 ERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSV---KYGRFQGQRVSAWELINS 839
ERC++D ETGL LLPL + + S + ++ V Q LI+
Sbjct: 2431 ERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDY 2490
Query: 840 EYFSEGRRRQLLRRYRQREVTL-----GQVAKLLEAETQRQADIMLPALRSRVTVHQLLE 894
E F E ++ E+T+ L++ +T Q DI ++
Sbjct: 2491 ETFKELCEQEC----EWEEITITGSDGSTRVVLVDRKTGSQYDI-----------QDAID 2535
Query: 895 AGIIDQQLLDQVLAGTIS----PEALLLMDGV-------------------RRYLCGLGA 931
G++D++ DQ +G++S + + L +GV + +
Sbjct: 2536 KGLVDRKFFDQYRSGSLSLTQFADMISLKNGVGTSSSMGSGVSDDVFSSSRHESVSKIST 2595
Query: 932 VGGVRLL-----------------------PSGQRLSLYQAMRQKLLGPRVALALLEAQA 968
+ VR L + +++S+ + + + ++ LLEAQA
Sbjct: 2596 ISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQA 2655
Query: 969 ATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKK 1028
TG I+ P + + LS+ +AV +GV+ ++ RLK A+ A GF K++S +A+K+
Sbjct: 2656 CTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKE 2715
Query: 1029 GLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETAL---SSSSETFP 1085
+P+E R LE Q TGG++DP H + AI++G++D L SS ++
Sbjct: 2716 KWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILT 2775
Query: 1086 TPDGQGRTSYAQLLEECPRDETSGLHLLPLPE-SAPALPTEEQVQRSLQAVPGAKDGT 1142
P + + SY + ++ +GL LL S+ LP+ ++ + PG++ G+
Sbjct: 2776 CPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPS----PYNMSSAPGSRSGS 2829
Score = 345 bits (885), Expect = 7e-94
Identities = 253/814 (31%), Positives = 406/814 (49%), Gaps = 68/814 (8%)
Query: 40 ARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKAL 99
A SIAG + S+ A + L+ LLEAQAATGG++D R + L V A+
Sbjct: 2015 AGSIAGASASPK-EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAI 2073
Query: 100 QQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGG 159
+ L+ + ++++ AAE+A TG+ DP+ G+ +++ +AI K ++DR G LE Q+A+GG
Sbjct: 2074 ARDLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGG 2133
Query: 160 LVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCV 219
+VDP V + + A +GL+DR+ + L++ P F++P T ++++Y QL ERC
Sbjct: 2134 VVDPVNSVFLPKDVALARGLIDRDLYRSLND--PRDSQKNFVDPVTKKKVSYVQLKERCR 2191
Query: 220 RAPGSGLALLPLK---ITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAE 276
P +GL LL ++ ++F+ + V+ EL++ GIL V L G+++ +V R
Sbjct: 2192 IEPHTGLLLLSVQKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGER-- 2249
Query: 277 VRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQR 336
++ +L+G+ +AG+ K ++A L+ GTAL LLEAQAAT +VDP++ R
Sbjct: 2250 IKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLR 2309
Query: 337 LWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLD 396
L V+EA + GLV E E+LL AE+AVTG++DP +G+ I LFQAM K L+++ +RLL+
Sbjct: 2310 LPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLE 2369
Query: 397 AQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLSQ-----AGSFSDGTHGGLRYEQL 451
AQ+ATGG++ P RLP++ A + G +E+ LS G F T L Y QL
Sbjct: 2370 AQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQL 2429
Query: 452 LALCVTDPETGLAFLPLSGGPRGGEPQGPPFIK--------------YSTRQALSTATAT 497
C+ D ETGL LPL + + ++ S ++A
Sbjct: 2430 KERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLID 2489
Query: 498 VSVGKFRGRPVSLWELLFSEAISSEQRAMLA------------------------QQYQE 533
K WE + R +L QY+
Sbjct: 2490 YETFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRS 2549
Query: 534 GTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATA 593
G+LS+ + A +S L+ T+ SG+ D ++ +E + +T
Sbjct: 2550 GSLSLTQFADMIS--LKNGVGTSSSMGSGVSD----------DVFSSSRHESVSK-ISTI 2596
Query: 594 KDVGSL----ASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAA 649
V +L +S L+ + IA + + E++SI E +G++ T LLEAQA
Sbjct: 2597 SSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQAC 2656
Query: 650 TGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKG 709
TG II P + S+++A+ VI D+ +L A++A G+ +++S +A+++
Sbjct: 2657 TGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEK 2716
Query: 710 LIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFD 769
+ E G R LE Q TGG++DP R+ + A R+G+ D L D S K
Sbjct: 2717 WLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTC 2776
Query: 770 PNTHENLTYLQLLERCVRDPETGLYLLPLSSTQS 803
P T ++Y + R + + TGL LL +S S
Sbjct: 2777 PKTKLKISYKDAINRSMVEDITGLRLLEAASVSS 2810
Score = 330 bits (847), Expect = 2e-89
Identities = 215/519 (41%), Positives = 294/519 (56%), Gaps = 34/519 (6%)
Query: 1927 ATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDT 1986
A L E Q LD + K SV+E V E++ L A A P +
Sbjct: 1977 AMQLYECQLIDKTTLDKLLKGKKSVEE------VASEIQPFLRGAGSIAGASASPK--EK 2028
Query: 1987 IPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISD 2046
L +A +K+LI + LLE Q ATGG+IDP + +L +++A R + D I
Sbjct: 2029 YSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYA 2088
Query: 2047 QKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALEAE 2106
+ F DP + + VS E ++ +TG L A S + D +
Sbjct: 2089 AEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIA---SGGVVDPVNSVFLPK 2145
Query: 2107 QVEITVGR-----FRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILEL 2161
V + G +R + N +KK+ V++ R ++ L+L
Sbjct: 2146 DVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKE---RCRIEPHTGLLLLS 2202
Query: 2162 IEKQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLE 2221
++K+ S FQGIR+ +T +EL+ S I+ + +LE+G+ + E+ E R+K +L+
Sbjct: 2203 VQKRSMS-----FQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGE--RIKDFLQ 2255
Query: 2222 GTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRL 2281
G+SCIAG+ Q K+ IY+AM G++RPGTAL LLEAQAATGF++DPV NLRL
Sbjct: 2256 GSSCIAGIYNETTKQ-----KLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRL 2310
Query: 2282 SVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEA 2341
VEE G+VG E +EKLLSAERAVTGY DP TG ISLFQAM K+LI + HGIRLLEA
Sbjct: 2311 PVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEA 2370
Query: 2342 QIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLL 2401
QIATGG+IDP SHR+PVD+AY+RGYF+EE++ +L+DPSDDTKGFFDPNT ENLTY+QL
Sbjct: 2371 QIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLK 2430
Query: 2402 RRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARV 2440
RC+ D +TGL +L L + Q+ + LR RV
Sbjct: 2431 ERCIKDEETGLCLLPLKEKKK---QVQTSQKNTLRKRRV 2466
Score = 319 bits (818), Expect = 4e-86
Identities = 248/865 (28%), Positives = 410/865 (47%), Gaps = 90/865 (10%)
Query: 1621 RKLTVEEAFKAGMFGKETYVKLLSAERAV---TGYTDPYTG-------------QQISLF 1664
+K+T + ++ + K T KLL +++V P+ ++ SL
Sbjct: 1973 KKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGSIAGASASPKEKYSLV 2032
Query: 1665 QAMQKDLIVREHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDD 1724
+A +K LI E + LLEAQ ATGGIIDP + ++ VD A D + + +
Sbjct: 2033 EAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKA 2092
Query: 1725 TKGFFDPNTHENLTYLQLLERCVEDPETGLYLL--QIIKKGE----NYVYINE--ATRHV 1776
GF DP + + ++ + +++ + D ETG+ LL QI G N V++ + A
Sbjct: 2093 ITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARG 2152
Query: 1777 LQSRTAKMRVGRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIE 1836
L R + D +F D ++ + + +E + +E ++ +++
Sbjct: 2153 LIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCR--------IEPHTGLLLLSVQ 2204
Query: 1837 ETETQNQGIKVAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGS 1896
+ QGI R VT +L +S ++ T++ L G+ + E +K +L+GS
Sbjct: 2205 KRSMSFQGI-----RQPVTVTELVDSGILRPSTVNELESGQISYDEVG--ERIKDFLQGS 2257
Query: 1897 DCIAGVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVD 1956
CIAG+ +T++ + ++EA + L+ A LLEAQAATGF++DP + +L V+EA
Sbjct: 2258 SCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYK 2317
Query: 1957 VGLVNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGV 2016
GLV E +E+LL AERA TGY DP TG+ I LFQAM K+LIEK +RLLE Q+ATGG+
Sbjct: 2318 RGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGI 2377
Query: 2017 IDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQE 2076
IDP+ HRLP++ AY+RG ++++ ++SD K F DPNT+E ++Y +L+ERC E
Sbjct: 2378 IDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDE 2437
Query: 2077 DTGWVLFPVNKAARDSEH-------------IDDETRRAL-------------------- 2103
+TG L P+ + + + +D ET + +
Sbjct: 2438 ETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELC 2497
Query: 2104 --EAEQVEITVGRFRGQKPTLWA--LLNSEYVTEE--KKLQLVRMYRTHTRRALQTVAQL 2157
E E EIT+ G + S+Y ++ K + R + R ++ Q
Sbjct: 2498 EQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQF 2557
Query: 2158 ILELIEKQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVK 2217
+ K G+ + +S E + + T S +
Sbjct: 2558 ADMISLKNGVGTSSSMGSGVSDDVFSSS-------RHESVSKISTISSVRNLTIRSSSFS 2610
Query: 2218 RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVR 2277
LE +S IA + EK+SI + + +G++ T LLEAQA TG +I P
Sbjct: 2611 DTLEESSPIAAIF-----DTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTT 2665
Query: 2278 NLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIR 2337
+LS+++ V GV+ ++ +L A++A G+ +++S +A+++ + E G R
Sbjct: 2666 GQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQR 2725
Query: 2338 LLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTY 2397
LE Q TGG++DP R+ + A R+G+ D + L D S K P T ++Y
Sbjct: 2726 FLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISY 2785
Query: 2398 VQLLRRCVPDPDTGLYMLQLAGRGS 2422
+ R + + TGL +L+ A S
Sbjct: 2786 KDAINRSMVEDITGLRLLEAASVSS 2810
Score = 296 bits (758), Expect = 4e-79
Identities = 157/269 (58%), Positives = 197/269 (73%), Gaps = 10/269 (3%)
Query: 2706 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 2765
+SF+G+R+ V+ +EL SGIL P T+ +L G + EV E +K +L+G+SCIAG+
Sbjct: 2208 MSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGER--IKDFLQGSSCIAGIYN 2265
Query: 2766 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 2825
Q K+ IY+AM G++RPGTAL LLEAQAATGF++DPV NLRL VEEA G+
Sbjct: 2266 ETTKQ-----KLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGL 2320
Query: 2826 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 2885
VG E +EKLLSAERAVTGY DP TG ISLFQAM K+LI + HGIRLLEAQIATGG+IDP
Sbjct: 2321 VGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDP 2380
Query: 2886 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTG 2945
SHR+PVD+AY+RGYF+EE++ +L+DPSDDTKGFFDPNT ENLTY+QL RC+ D +TG
Sbjct: 2381 KESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETG 2440
Query: 2946 LYMLQLAGRGSAVHQLSEELRCALRDARV 2974
L +L L + Q+ + LR RV
Sbjct: 2441 LCLLPLKEKKK---QVQTSQKNTLRKRRV 2466
Score = 296 bits (758), Expect = 4e-79
Identities = 157/269 (58%), Positives = 197/269 (73%), Gaps = 10/269 (3%)
Query: 3240 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 3299
+SF+G+R+ V+ +EL SGIL P T+ +L G + EV E +K +L+G+SCIAG+
Sbjct: 2208 MSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGER--IKDFLQGSSCIAGIYN 2265
Query: 3300 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 3359
Q K+ IY+AM G++RPGTAL LLEAQAATGF++DPV NLRL VEEA G+
Sbjct: 2266 ETTKQ-----KLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGL 2320
Query: 3360 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 3419
VG E +EKLLSAERAVTGY DP TG ISLFQAM K+LI + HGIRLLEAQIATGG+IDP
Sbjct: 2321 VGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDP 2380
Query: 3420 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTG 3479
SHR+PVD+AY+RGYF+EE++ +L+DPSDDTKGFFDPNT ENLTY+QL RC+ D +TG
Sbjct: 2381 KESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETG 2440
Query: 3480 LYMLQLAGRGSAVHQLSEELRCALRDARV 3508
L +L L + Q+ + LR RV
Sbjct: 2441 LCLLPLKEKKK---QVQTSQKNTLRKRRV 2466
Score = 296 bits (758), Expect = 4e-79
Identities = 157/269 (58%), Positives = 197/269 (73%), Gaps = 10/269 (3%)
Query: 3774 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 3833
+SF+G+R+ V+ +EL SGIL P T+ +L G + EV E +K +L+G+SCIAG+
Sbjct: 2208 MSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGER--IKDFLQGSSCIAGIYN 2265
Query: 3834 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 3893
Q K+ IY+AM G++RPGTAL LLEAQAATGF++DPV NLRL VEEA G+
Sbjct: 2266 ETTKQ-----KLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGL 2320
Query: 3894 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 3953
VG E +EKLLSAERAVTGY DP TG ISLFQAM K+LI + HGIRLLEAQIATGG+IDP
Sbjct: 2321 VGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDP 2380
Query: 3954 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTG 4013
SHR+PVD+AY+RGYF+EE++ +L+DPSDDTKGFFDPNT ENLTY+QL RC+ D +TG
Sbjct: 2381 KESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETG 2440
Query: 4014 LYMLQLAGRGSAVHQLSEELRCALRDARV 4042
L +L L + Q+ + LR RV
Sbjct: 2441 LCLLPLKEKKK---QVQTSQKNTLRKRRV 2466
Score = 296 bits (758), Expect = 4e-79
Identities = 157/269 (58%), Positives = 197/269 (73%), Gaps = 10/269 (3%)
Query: 4308 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 4367
+SF+G+R+ V+ +EL SGIL P T+ +L G + EV E +K +L+G+SCIAG+
Sbjct: 2208 MSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGER--IKDFLQGSSCIAGIYN 2265
Query: 4368 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 4427
Q K+ IY+AM G++RPGTAL LLEAQAATGF++DPV NLRL VEEA G+
Sbjct: 2266 ETTKQ-----KLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGL 2320
Query: 4428 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 4487
VG E +EKLLSAERAVTGY DP TG ISLFQAM K+LI + HGIRLLEAQIATGG+IDP
Sbjct: 2321 VGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDP 2380
Query: 4488 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTG 4547
SHR+PVD+AY+RGYF+EE++ +L+DPSDDTKGFFDPNT ENLTY+QL RC+ D +TG
Sbjct: 2381 KESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETG 2440
Query: 4548 LYMLQLAGRGSAVHQLSEELRCALRDARV 4576
L +L L + Q+ + LR RV
Sbjct: 2441 LCLLPLKEKKK---QVQTSQKNTLRKRRV 2466
Score = 293 bits (750), Expect = 3e-78
Identities = 153/246 (62%), Positives = 187/246 (76%), Gaps = 7/246 (2%)
Query: 4842 VSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLV 4901
+SF+G+R+ V+ +EL SGIL P T+ +L G + EV E +K +L+G+SCIAG+
Sbjct: 2208 MSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGER--IKDFLQGSSCIAGIYN 2265
Query: 4902 PAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGV 4961
Q K+ IY+AM G++RPGTAL LLEAQAATGF++DPV NLRL VEEA G+
Sbjct: 2266 ETTKQ-----KLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGL 2320
Query: 4962 VGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 5021
VG E +EKLLSAERAVTGY DP TG ISLFQAM K+LI + HGIRLLEAQIATGG+IDP
Sbjct: 2321 VGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDP 2380
Query: 5022 VHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETG 5081
SHR+PVD+AY+RGYF+EE++ +L+DPSDDTKGFFDPNT ENLTYLQL +R D ETG
Sbjct: 2381 KESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETG 2440
Query: 5082 LLFLSL 5087
L L L
Sbjct: 2441 LCLLPL 2446
Score = 288 bits (737), Expect = 1e-76
Identities = 246/882 (27%), Positives = 409/882 (46%), Gaps = 70/882 (7%)
Query: 1521 FRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLEGGNFIAGVLIQG 1580
F GLRK+V+A L+ QLI + TLD+L +G +V+EVA ++ L G IAG
Sbjct: 1968 FDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGASAS- 2024
Query: 1581 TQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFKAGMFGKETYV 1640
+E+ S+ EA R+ ++ P + ++LLEAQAATG IIDP N KLTV+ A + +
Sbjct: 2025 PKEKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQ 2084
Query: 1641 KLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGIIDPVHSHRVP 1700
++ +AE+A+TG+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GG++DPV+S +P
Sbjct: 2085 QIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLP 2144
Query: 1701 VDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLYLLQII 1760
DVA G D ++ R L DP D K F DP T + ++Y+QL ERC +P TGL LL +
Sbjct: 2145 KDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQ 2204
Query: 1761 KKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQ 1820
K+ ++ I + + T + G V+ L S + D E I+++
Sbjct: 2205 KRSMSFQGIRQPV-----TVTELVDSGILRPSTVNE---LESGQISYDEVGERIKDFLQG 2256
Query: 1821 SGGLEKLLEIITTTIEETETQNQGIKVAAIRGEV---TAADLFNSR-----VIDQKTLHT 1872
S I ET Q GI A G V TA +L ++ ++D +
Sbjct: 2257 SS-------CIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLR 2309
Query: 1873 LRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFATWLLE 1932
L V + L +E + L + G P T ++SL +A KELI LLE
Sbjct: 2310 LPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLE 2369
Query: 1933 AQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTIPLFQA 1992
AQ ATG ++DP +L VD A G NEEL E L G+ DP T + + Q
Sbjct: 2370 AQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQL 2429
Query: 1993 MQKQLIEKAEALRLLEV-----QVATGG----------VIDPQHHHRLPLETAYRRGCLH 2037
++ + ++ L LL + QV T ++DP+ + + ++ AY++G +
Sbjct: 2430 KERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLID 2489
Query: 2038 KDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDD 2097
+ + + +Q+ + + + + Q D + ++K D + D
Sbjct: 2490 YETFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQYD---IQDAIDKGLVDRKFFDQ 2546
Query: 2098 ETRRALEAEQVE--ITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVA 2155
+L Q I++ G ++ + ++ + + + + ++ + R L +
Sbjct: 2547 YRSGSLSLTQFADMISLKNGVGTSSSMGSGVSDDVFSSSRHESVSKISTISSVRNLTIRS 2606
Query: 2156 QLILELIEKQ---------ETSNKHLWFQGIRR----QITASELLSSAIITEEML----- 2197
+ +E+ E K +GI R IT LL + T ++
Sbjct: 2607 SSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTG 2666
Query: 2198 QDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPG 2257
Q L + +Q +++ D R G + ++KMS +A+ + L
Sbjct: 2667 QKLSLQDAVSQGVIDQDMATRLKPAQKAFIGF-----EGVKGKKKMSAAEAVKEKWLPYE 2721
Query: 2258 TALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQ 2317
LE Q TG ++DP + R+S EE + G + ++L T P T
Sbjct: 2722 AGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKL 2781
Query: 2318 QISLFQAMQKDLIVREHGIRLLE-AQIATGGVIDPVHSHRVP 2358
+IS A+ + ++ G+RLLE A +++ G+ P + P
Sbjct: 2782 KISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAP 2823
Score = 235 bits (600), Expect = 7e-61
Identities = 175/566 (30%), Positives = 285/566 (50%), Gaps = 63/566 (11%)
Query: 544 ELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASAQ 603
E E T+++ F GLR VT +L + ++ID+ ++L G+ + ++V S Q
Sbjct: 1952 ETQTECEWTVDTSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQ 2009
Query: 604 RYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHS 663
+L+G G IAG +E+ S+ EA+ K L+ P + ++LLEAQAATG IIDP N+ +
Sbjct: 2010 PFLRGAGSIAGASA-SPKEKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLT 2068
Query: 664 VEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQ 723
V+ A+ +I D ++ +AE+A+TG+ DP++G+ +S+ +A++K LI RE G+RLLEAQ
Sbjct: 2069 VDSAIARDLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQ 2128
Query: 724 IATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLE 783
IA+GGV+DPV+S +P DVA RG D+ L L DP D K F DP T + ++Y+QL E
Sbjct: 2129 IASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKE 2188
Query: 784 RCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFS 843
RC +P TGL LL + +FQ + Q V+ EL++S
Sbjct: 2189 RCRIEPHTGLLLLSVQK---------RSMSFQGI----------RQPVTVTELVDSGIL- 2228
Query: 844 EGRRRQLLRRYRQREVTLGQVAKLLEAETQRQ---ADIMLPALRSRVTVHQLLEAGII-- 898
R + +++ +V + ++ Q A I + ++ +++ ++ G++
Sbjct: 2229 ---RPSTVNELESGQISYDEVGERIKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRP 2285
Query: 899 -------DQQLLDQVLAGTISPEALLLMDGVRRYLCGL----------GAVGGVRLLPSG 941
+ Q + +S L + + +R L G+ AV G +G
Sbjct: 2286 GTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETG 2345
Query: 942 QRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRL 1001
+SL+QAM ++L+ + LLEAQ ATG I+DP L VD A +RG EL L
Sbjct: 2346 NIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEIL 2405
Query: 1002 KRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLL-----EAQVATGG-------- 1048
GF DP + + ++ Q ++ + E LL + QV T
Sbjct: 2406 SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRR 2465
Query: 1049 --IIDPTSHHHLPMPVAIQRGYVDQE 1072
I+DP ++ + + A ++G +D E
Sbjct: 2466 VVIVDPETNKEMSVQEAYKKGLIDYE 2491
Score = 228 bits (581), Expect = 1e-58
Identities = 174/594 (29%), Positives = 297/594 (50%), Gaps = 37/594 (6%)
Query: 1806 TEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQ------NQGIKVAAIRGEVTAADL 1859
T + + +L E ++KL + + ET+T+ + +R +VTA L
Sbjct: 1921 TRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQL 1980
Query: 1860 FNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRK 1919
+ ++ID+ TL L G+ + +++ ++P+L G+ IAG + S +E SL EA RK
Sbjct: 1981 YECQLIDKTTLDKLLKGKKSVEEVASE--IQPFLRGAGSIAGASA-SPKEKYSLVEAKRK 2037
Query: 1920 ELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYR 1979
+LI LLEAQAATG ++DP +KL+VD A+ L++ + R+++ AE+A TG+
Sbjct: 2038 KLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAITGFD 2097
Query: 1980 DPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKD 2039
DP +G T+ + +A++K LI++ +RLLE Q+A+GGV+DP + LP + A RG + +D
Sbjct: 2098 DPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARGLIDRD 2157
Query: 2040 IYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDET 2099
+Y ++D + +K FVDP T++KVSY +L+ERCR + TG +L V K + + I
Sbjct: 2158 LYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRSMSFQGI---R 2214
Query: 2100 RRALEAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLIL 2159
+ E V+ + R P+ L S ++ ++ + ++ + + +A +
Sbjct: 2215 QPVTVTELVDSGILR-----PSTVNELESGQISYDEVGERIKDF----LQGSSCIAGIYN 2265
Query: 2160 ELIEKQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRY 2219
E KQ+ G+ R TA ELL + T ++ + R +E + V
Sbjct: 2266 E-TTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIE 2324
Query: 2220 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 2279
+ A V + P +S++QAM K ++ G + LLEAQ ATG +IDP +
Sbjct: 2325 FKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESH 2384
Query: 2280 RLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL 2339
RL V+ G E+ E L G+ DP T + ++ Q ++ + E G+ LL
Sbjct: 2385 RLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLL 2444
Query: 2340 -----EAQIATGG----------VIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 2378
+ Q+ T ++DP + + V AY++G D E + L +
Sbjct: 2445 PLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCE 2498
Score = 213 bits (543), Expect = 3e-54
Identities = 234/890 (26%), Positives = 391/890 (43%), Gaps = 93/890 (10%)
Query: 232 KITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVV 291
K+ F + V+A +L E ++D+ + L +G+ + +V++ E++ +L G GS+AG
Sbjct: 1965 KLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGAS 2022
Query: 292 LLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPE 351
P+ K S +A + L+ + + LLEAQAAT ++DP ++L VD A+ L+ +
Sbjct: 2023 ASPK-EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFD 2081
Query: 352 LHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRL 411
+Q+ AE+A+TG DPFSG + + +A+KK L+DR +RLL+AQ+A+GG+V P +
Sbjct: 2082 DRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSV 2141
Query: 412 RLPLEAALRCGCLDEDTQRQL-----SQAGSFSDGTHGGLRYEQLLALCVTDPETGLAFL 466
LP + AL G +D D R L SQ T + Y QL C +P TGL L
Sbjct: 2142 FLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGL--L 2199
Query: 467 PLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAM 526
LS R QG RQ + T T V G R V+ E S IS ++
Sbjct: 2200 LLSVQKRSMSFQG-------IRQPV-TVTELVDSGILRPSTVNELE---SGQISYDEVGE 2248
Query: 527 LAQQYQEGTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAE-----IIDQD 581
+ + +G+ + A + T +Q GL T ELL+A+ I+D
Sbjct: 2249 RIKDFLQGSSCI---AGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPV 2305
Query: 582 LYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTAL 641
RL +A + + + ++ L + G P + +S+++A K L+ G +
Sbjct: 2306 SNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI 2365
Query: 642 ILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQIS 701
LLEAQ ATG IIDPK + V+ A + ++ L G+ DP T + ++
Sbjct: 2366 RLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLT 2425
Query: 702 LFQAMQKGLIVREHGIRLL-----EAQIATGG----------VIDPVHSHRVPVDVAYRR 746
Q ++ + E G+ LL + Q+ T ++DP + + V AY++
Sbjct: 2426 YLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKK 2485
Query: 747 GYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSPLV 806
G D L + + + + + T + L++R +TG + LV
Sbjct: 2486 GLIDYETFKELCEQECEWEEITITGS-DGSTRVVLVDR-----KTGSQYDIQDAIDKGLV 2539
Query: 807 D------------SATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQL---- 850
D S TQ A ++S+K G G S ++ + FS R +
Sbjct: 2540 DRKFFDQYRSGSLSLTQFAD---MISLKNG--VGTSSSMGSGVSDDVFSSSRHESVSKIS 2594
Query: 851 -LRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIID----QQLLD- 904
+ R + + LE E+ A I ++++ + +E GI+D Q+LL+
Sbjct: 2595 TISSVRNLTIRSSSFSDTLE-ESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEA 2653
Query: 905 -QVLAGTISP---EALLLMDGV----------RRYLCGLGAVGGVRLLPSGQRLSLYQAM 950
G I P + L L D V R A G + +++S +A+
Sbjct: 2654 QACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAV 2713
Query: 951 RQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAG 1010
++K L LE Q TG ++DP +S +EA+R+G + RL+
Sbjct: 2714 KEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKI 2773
Query: 1011 FRDPFSGKQVSVFQAMKKGLIPWEQAARLLE-AQVATGGIIDPTSHHHLP 1059
P + ++S A+ + ++ RLLE A V++ G+ P + P
Sbjct: 2774 LTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAP 2823
Score = 198 bits (504), Expect = 1e-49
Identities = 105/248 (42%), Positives = 167/248 (67%), Gaps = 8/248 (3%)
Query: 4840 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 4899
SK+ F GLR++V+A +L+ ++ TL L +G K+++EV ++ +L G IAG
Sbjct: 1964 SKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGA 2021
Query: 4900 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 4959
K EK S+ +A K ++ P + ++LLEAQAATG +IDP RN +L+V+ A+A
Sbjct: 2022 SASPK------EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIAR 2075
Query: 4960 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 5019
++ + ++++ +AE+A+TG+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GGV+
Sbjct: 2076 DLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVV 2135
Query: 5020 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPE 5079
DPV+S +P DVA RG D ++ R L DP D K F DP T + ++Y+QL +R ++P
Sbjct: 2136 DPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPH 2195
Query: 5080 TGLLFLSL 5087
TGLL LS+
Sbjct: 2196 TGLLLLSV 2203
Score = 197 bits (501), Expect = 2e-49
Identities = 106/251 (42%), Positives = 166/251 (66%), Gaps = 8/251 (3%)
Query: 2704 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 2763
SK+ F GLR++V+A +L+ ++ TL L +G K+++EV ++ +L G IAG
Sbjct: 1964 SKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGA 2021
Query: 2764 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 2823
K EK S+ +A K ++ P + ++LLEAQAATG +IDP RN +L+V+ A+A
Sbjct: 2022 SASPK------EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIAR 2075
Query: 2824 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 2883
++ + ++++ +AE+A+TG+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GGV+
Sbjct: 2076 DLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVV 2135
Query: 2884 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 2943
DPV+S +P DVA RG D ++ R L DP D K F DP T + ++YVQL RC +P
Sbjct: 2136 DPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPH 2195
Query: 2944 TGLYMLQLAGR 2954
TGL +L + R
Sbjct: 2196 TGLLLLSVQKR 2206
Score = 197 bits (501), Expect = 2e-49
Identities = 106/251 (42%), Positives = 166/251 (66%), Gaps = 8/251 (3%)
Query: 3238 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 3297
SK+ F GLR++V+A +L+ ++ TL L +G K+++EV ++ +L G IAG
Sbjct: 1964 SKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGA 2021
Query: 3298 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 3357
K EK S+ +A K ++ P + ++LLEAQAATG +IDP RN +L+V+ A+A
Sbjct: 2022 SASPK------EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIAR 2075
Query: 3358 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 3417
++ + ++++ +AE+A+TG+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GGV+
Sbjct: 2076 DLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVV 2135
Query: 3418 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 3477
DPV+S +P DVA RG D ++ R L DP D K F DP T + ++YVQL RC +P
Sbjct: 2136 DPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPH 2195
Query: 3478 TGLYMLQLAGR 3488
TGL +L + R
Sbjct: 2196 TGLLLLSVQKR 2206
Score = 197 bits (501), Expect = 2e-49
Identities = 106/251 (42%), Positives = 166/251 (66%), Gaps = 8/251 (3%)
Query: 3772 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 3831
SK+ F GLR++V+A +L+ ++ TL L +G K+++EV ++ +L G IAG
Sbjct: 1964 SKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGA 2021
Query: 3832 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 3891
K EK S+ +A K ++ P + ++LLEAQAATG +IDP RN +L+V+ A+A
Sbjct: 2022 SASPK------EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIAR 2075
Query: 3892 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 3951
++ + ++++ +AE+A+TG+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GGV+
Sbjct: 2076 DLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVV 2135
Query: 3952 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 4011
DPV+S +P DVA RG D ++ R L DP D K F DP T + ++YVQL RC +P
Sbjct: 2136 DPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPH 2195
Query: 4012 TGLYMLQLAGR 4022
TGL +L + R
Sbjct: 2196 TGLLLLSVQKR 2206
Score = 197 bits (501), Expect = 2e-49
Identities = 106/251 (42%), Positives = 166/251 (66%), Gaps = 8/251 (3%)
Query: 4306 SKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGV 4365
SK+ F GLR++V+A +L+ ++ TL L +G K+++EV ++ +L G IAG
Sbjct: 1964 SKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVAS--EIQPFLRGAGSIAGA 2021
Query: 4366 LVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAA 4425
K EK S+ +A K ++ P + ++LLEAQAATG +IDP RN +L+V+ A+A
Sbjct: 2022 SASPK------EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIAR 2075
Query: 4426 GVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVI 4485
++ + ++++ +AE+A+TG+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GGV+
Sbjct: 2076 DLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVV 2135
Query: 4486 DPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPD 4545
DPV+S +P DVA RG D ++ R L DP D K F DP T + ++YVQL RC +P
Sbjct: 2136 DPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPH 2195
Query: 4546 TGLYMLQLAGR 4556
TGL +L + R
Sbjct: 2196 TGLLLLSVQKR 2206
Score = 191 bits (485), Expect = 2e-47
Identities = 120/351 (34%), Positives = 198/351 (56%), Gaps = 28/351 (7%)
Query: 2070 ERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSE 2129
ER + + + + + + + + I++ RR LE E T + ++ S
Sbjct: 1884 EREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRE-TQSQLETER--------SR 1934
Query: 2130 YVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSS 2189
Y E KL+ R Y +H R QT + ++ L F G+R+++TA +L
Sbjct: 1935 YQREIDKLRQ-RPYGSH--RETQTECEWTVD--------TSKLVFDGLRKKVTAMQLYEC 1983
Query: 2190 AIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAM 2249
+I + L L G+ + +E+ + ++ +L G IAG K EK S+ +A
Sbjct: 1984 QLIDKTTLDKLLKGKKSVEEVASE--IQPFLRGAGSIAGASASPK------EKYSLVEAK 2035
Query: 2250 WKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTG 2309
K ++ P + ++LLEAQAATG +IDP RN +L+V+ + ++ + ++++ +AE+A+TG
Sbjct: 2036 RKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAITG 2095
Query: 2310 YTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFD 2369
+ DP++G+ +S+ +A++K+LI RE G+RLLEAQIA+GGV+DPV+S +P DVA RG D
Sbjct: 2096 FDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARGLID 2155
Query: 2370 EEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGR 2420
++ R L DP D K F DP T + ++YVQL RC +P TGL +L + R
Sbjct: 2156 RDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKR 2206
Score = 97.1 bits (240), Expect = 4e-19
Identities = 58/182 (31%), Positives = 99/182 (54%)
Query: 2775 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 2834
EK+SI + + +G++ T LLEAQA TG +I P +LS+++AV+ GV+ ++ +L
Sbjct: 2629 EKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRL 2688
Query: 2835 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 2894
A++A G+ +++S +A+++ + E G R LE Q TGG++DP R+ +
Sbjct: 2689 KPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTE 2748
Query: 2895 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGR 2954
A R+G+ D + L D S K P T ++Y + R + + TGL +L+ A
Sbjct: 2749 EAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASV 2808
Query: 2955 GS 2956
S
Sbjct: 2809 SS 2810
Score = 97.1 bits (240), Expect = 4e-19
Identities = 58/182 (31%), Positives = 99/182 (54%)
Query: 3309 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 3368
EK+SI + + +G++ T LLEAQA TG +I P +LS+++AV+ GV+ ++ +L
Sbjct: 2629 EKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRL 2688
Query: 3369 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 3428
A++A G+ +++S +A+++ + E G R LE Q TGG++DP R+ +
Sbjct: 2689 KPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTE 2748
Query: 3429 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGR 3488
A R+G+ D + L D S K P T ++Y + R + + TGL +L+ A
Sbjct: 2749 EAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASV 2808
Query: 3489 GS 3490
S
Sbjct: 2809 SS 2810
Score = 97.1 bits (240), Expect = 4e-19
Identities = 58/182 (31%), Positives = 99/182 (54%)
Query: 3843 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 3902
EK+SI + + +G++ T LLEAQA TG +I P +LS+++AV+ GV+ ++ +L
Sbjct: 2629 EKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRL 2688
Query: 3903 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 3962
A++A G+ +++S +A+++ + E G R LE Q TGG++DP R+ +
Sbjct: 2689 KPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTE 2748
Query: 3963 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGR 4022
A R+G+ D + L D S K P T ++Y + R + + TGL +L+ A
Sbjct: 2749 EAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASV 2808
Query: 4023 GS 4024
S
Sbjct: 2809 SS 2810
Score = 97.1 bits (240), Expect = 4e-19
Identities = 58/182 (31%), Positives = 99/182 (54%)
Query: 4377 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 4436
EK+SI + + +G++ T LLEAQA TG +I P +LS+++AV+ GV+ ++ +L
Sbjct: 2629 EKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRL 2688
Query: 4437 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 4496
A++A G+ +++S +A+++ + E G R LE Q TGG++DP R+ +
Sbjct: 2689 KPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTE 2748
Query: 4497 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGR 4556
A R+G+ D + L D S K P T ++Y + R + + TGL +L+ A
Sbjct: 2749 EAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASV 2808
Query: 4557 GS 4558
S
Sbjct: 2809 SS 2810
Score = 95.9 bits (237), Expect = 9e-19
Identities = 56/179 (31%), Positives = 97/179 (54%), Gaps = 2/179 (1%)
Query: 1259 KASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLG 1318
K SI + + G++ + GQRLLEAQ +G ++ P Q+LS++DAV G++ ++++ +L
Sbjct: 2630 KISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLK 2689
Query: 1319 QAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDP-VHGVHLPQA 1377
A++A G+ + +S +A+++ +P G L+ Q TGG+VDP VHG +
Sbjct: 2690 PAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHG-RISTE 2748
Query: 1378 AACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPS 1436
A R G +D + +Q L K P + +++Y+ R + + TGL LL S
Sbjct: 2749 EAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAAS 2807
Score = 95.1 bits (235), Expect = 2e-18
Identities = 56/175 (32%), Positives = 96/175 (54%)
Query: 4911 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 4970
EK+SI + + +G++ T LLEAQA TG +I P +LS+++AV+ GV+ ++ +L
Sbjct: 2629 EKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRL 2688
Query: 4971 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 5030
A++A G+ +++S +A+++ + E G R LE Q TGG++DP R+ +
Sbjct: 2689 KPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTE 2748
Query: 5031 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFL 5085
A R+G+ D + L D S K P T ++Y + R+ ++ TGL L
Sbjct: 2749 EAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLL 2803
Score = 89.4 bits (220), Expect = 9e-17
Identities = 55/191 (28%), Positives = 100/191 (52%), Gaps = 2/191 (1%)
Query: 39 QARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKA 98
++ IA ++ + + S+ +E+G++ + GQ LLEAQA TGG++ GQ L + A
Sbjct: 2615 ESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDA 2674
Query: 99 LQQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATG 158
+ QG++ ++ +L A++A G+ G +K++ +A+ ++ + GQ +LE Q TG
Sbjct: 2675 VSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTG 2734
Query: 159 GLVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERC 218
GLVDP ++ E A +G +D +L + L P T +++Y + R
Sbjct: 2735 GLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTC--PKTKLKISYKDAINRS 2792
Query: 219 VRAPGSGLALL 229
+ +GL LL
Sbjct: 2793 MVEDITGLRLL 2803
Score = 70.9 bits (172), Expect = 3e-11
Identities = 42/170 (24%), Positives = 82/170 (48%), Gaps = 7/170 (4%)
Query: 4920 WKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTG 4979
++G+ +P T L+++ ++ + + ++S +E GE + L + G
Sbjct: 2210 FQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEV-------GERIKDFLQGSSCIAG 2262
Query: 4980 YTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFD 5039
+ T Q++ +++AM+ L+ + LLEAQ ATG ++DPV + R+PV+ AY+RG
Sbjct: 2263 IYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVG 2322
Query: 5040 EEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSL 5089
E L G+ DP T ++ Q + + ++ G+ L +
Sbjct: 2323 IEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQI 2372
Score = 69.7 bits (169), Expect = 7e-11
Identities = 51/171 (29%), Positives = 82/171 (47%), Gaps = 8/171 (4%)
Query: 4919 MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVT 4978
++ G+ + TA+ L E Q +D + + SVEE V EIQ L A
Sbjct: 1967 VFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEE------VASEIQPFLRGAGSIAG 2020
Query: 4979 GYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYF 5038
P ++ SL +A +K LI E + LLEAQ ATGG+IDP + ++ VD A R
Sbjct: 2021 ASASPK--EKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI 2078
Query: 5039 DEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSL 5089
D + + + GF DP + + ++ + +++ +D ETG+ L +
Sbjct: 2079 DFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQI 2129
Score = 65.9 bits (159), Expect = 1e-09
Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 15/163 (9%)
Query: 2765 VPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAG 2824
V + P +S++QAM K ++ G + LLEAQ ATG +IDP + RL V+ A G
Sbjct: 2336 VTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRG 2395
Query: 2825 VVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL-----EAQIAT 2879
E+ E L G+ DP T + ++ Q ++ + E G+ LL + Q+ T
Sbjct: 2396 YFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQT 2455
Query: 2880 GG----------VIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 2912
++DP + + V AY++G D E + L +
Sbjct: 2456 SQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCE 2498
Score = 65.9 bits (159), Expect = 1e-09
Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 15/163 (9%)
Query: 3299 VPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAG 3358
V + P +S++QAM K ++ G + LLEAQ ATG +IDP + RL V+ A G
Sbjct: 2336 VTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRG 2395
Query: 3359 VVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL-----EAQIAT 3413
E+ E L G+ DP T + ++ Q ++ + E G+ LL + Q+ T
Sbjct: 2396 YFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQT 2455
Query: 3414 GG----------VIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 3446
++DP + + V AY++G D E + L +
Sbjct: 2456 SQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCE 2498
Score = 65.9 bits (159), Expect = 1e-09
Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 15/163 (9%)
Query: 3833 VPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAG 3892
V + P +S++QAM K ++ G + LLEAQ ATG +IDP + RL V+ A G
Sbjct: 2336 VTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRG 2395
Query: 3893 VVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL-----EAQIAT 3947
E+ E L G+ DP T + ++ Q ++ + E G+ LL + Q+ T
Sbjct: 2396 YFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQT 2455
Query: 3948 GG----------VIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 3980
++DP + + V AY++G D E + L +
Sbjct: 2456 SQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCE 2498
Score = 65.9 bits (159), Expect = 1e-09
Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 15/163 (9%)
Query: 4367 VPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAG 4426
V + P +S++QAM K ++ G + LLEAQ ATG +IDP + RL V+ A G
Sbjct: 2336 VTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRG 2395
Query: 4427 VVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL-----EAQIAT 4481
E+ E L G+ DP T + ++ Q ++ + E G+ LL + Q+ T
Sbjct: 2396 YFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQT 2455
Query: 4482 GG----------VIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 4514
++DP + + V AY++G D E + L +
Sbjct: 2456 SQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCE 2498
Score = 65.9 bits (159), Expect = 1e-09
Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 15/163 (9%)
Query: 4901 VPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAG 4960
V + P +S++QAM K ++ G + LLEAQ ATG +IDP + RL V+ A G
Sbjct: 2336 VTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRG 2395
Query: 4961 VVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLL-----EAQIAT 5015
E+ E L G+ DP T + ++ Q ++ + E G+ LL + Q+ T
Sbjct: 2396 YFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQT 2455
Query: 5016 GG----------VIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 5048
++DP + + V AY++G D E + L +
Sbjct: 2456 SQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCE 2498
Score = 62.8 bits (151), Expect = 9e-09
Identities = 43/168 (25%), Positives = 80/168 (47%), Gaps = 8/168 (4%)
Query: 4858 TSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQ 4917
T GI+ P L + +++ + D ++ I G D P + +S+ +
Sbjct: 2055 TGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAITGF-----DDPFSGKTVSVSE 2109
Query: 4918 AMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAV 4977
A+ K ++ T + LLEAQ A+G V+DPV ++ L + A+A G++ ++ L +
Sbjct: 2110 AIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQ 2169
Query: 4978 TGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQ---IATGGVIDPV 5022
+ DP T +++S Q ++ I G+ LL Q ++ G+ PV
Sbjct: 2170 KNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRSMSFQGIRQPV 2217
Score = 55.5 bits (132), Expect = 1e-06
Identities = 53/203 (26%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 2701 ERLSKVSF-----RGLRRQVSASELH-----TSGILGPETLRDLAQGTKTLQEVTEMDSV 2750
E L K+S RG+ ++ L T GI+ P T + L+ Q V + D
Sbjct: 2626 ENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMA 2685
Query: 2751 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 2810
R G + ++KMS +A+ + L LE Q TG ++DP
Sbjct: 2686 TRLKPAQKAFIGF-----EGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPE 2740
Query: 2811 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 2870
+ R+S EEA+ G + G ++L T P T +IS A+ + ++ G+
Sbjct: 2741 VHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGL 2800
Query: 2871 RLLE-AQIATGGVIDPVHSHRVP 2892
RLLE A +++ G+ P + P
Sbjct: 2801 RLLEAASVSSKGLPSPYNMSSAP 2823
Score = 55.5 bits (132), Expect = 1e-06
Identities = 53/203 (26%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 3235 ERLSKVSF-----RGLRRQVSASELH-----TSGILGPETLRDLAQGTKTLQEVTEMDSV 3284
E L K+S RG+ ++ L T GI+ P T + L+ Q V + D
Sbjct: 2626 ENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMA 2685
Query: 3285 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 3344
R G + ++KMS +A+ + L LE Q TG ++DP
Sbjct: 2686 TRLKPAQKAFIGF-----EGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPE 2740
Query: 3345 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 3404
+ R+S EEA+ G + G ++L T P T +IS A+ + ++ G+
Sbjct: 2741 VHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGL 2800
Query: 3405 RLLE-AQIATGGVIDPVHSHRVP 3426
RLLE A +++ G+ P + P
Sbjct: 2801 RLLEAASVSSKGLPSPYNMSSAP 2823
Score = 55.5 bits (132), Expect = 1e-06
Identities = 53/203 (26%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 3769 ERLSKVSF-----RGLRRQVSASELH-----TSGILGPETLRDLAQGTKTLQEVTEMDSV 3818
E L K+S RG+ ++ L T GI+ P T + L+ Q V + D
Sbjct: 2626 ENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMA 2685
Query: 3819 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 3878
R G + ++KMS +A+ + L LE Q TG ++DP
Sbjct: 2686 TRLKPAQKAFIGF-----EGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPE 2740
Query: 3879 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 3938
+ R+S EEA+ G + G ++L T P T +IS A+ + ++ G+
Sbjct: 2741 VHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGL 2800
Query: 3939 RLLE-AQIATGGVIDPVHSHRVP 3960
RLLE A +++ G+ P + P
Sbjct: 2801 RLLEAASVSSKGLPSPYNMSSAP 2823
Score = 55.5 bits (132), Expect = 1e-06
Identities = 53/203 (26%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 4303 ERLSKVSF-----RGLRRQVSASELH-----TSGILGPETLRDLAQGTKTLQEVTEMDSV 4352
E L K+S RG+ ++ L T GI+ P T + L+ Q V + D
Sbjct: 2626 ENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMA 2685
Query: 4353 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 4412
R G + ++KMS +A+ + L LE Q TG ++DP
Sbjct: 2686 TRLKPAQKAFIGF-----EGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPE 2740
Query: 4413 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 4472
+ R+S EEA+ G + G ++L T P T +IS A+ + ++ G+
Sbjct: 2741 VHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGL 2800
Query: 4473 RLLE-AQIATGGVIDPVHSHRVP 4494
RLLE A +++ G+ P + P
Sbjct: 2801 RLLEAASVSSKGLPSPYNMSSAP 2823
Score = 55.5 bits (132), Expect = 1e-06
Identities = 53/203 (26%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 4837 ERLSKVSF-----RGLRRQVSASELH-----TSGILGPETLRDLAQGTKTLQEVTEMDSV 4886
E L K+S RG+ ++ L T GI+ P T + L+ Q V + D
Sbjct: 2626 ENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMA 2685
Query: 4887 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 4946
R G + ++KMS +A+ + L LE Q TG ++DP
Sbjct: 2686 TRLKPAQKAFIGF-----EGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPE 2740
Query: 4947 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 5006
+ R+S EEA+ G + G ++L T P T +IS A+ + ++ G+
Sbjct: 2741 VHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGL 2800
Query: 5007 RLLE-AQIATGGVIDPVHSHRVP 5028
RLLE A +++ G+ P + P
Sbjct: 2801 RLLEAASVSSKGLPSPYNMSSAP 2823
Score = 37.4 bits (85), Expect = 0.38
Identities = 35/150 (23%), Positives = 62/150 (41%), Gaps = 7/150 (4%)
Query: 15 NSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQAL 74
++ Q + + MA L +P ++ G + S A+++ LP GQ
Sbjct: 2673 DAVSQGVIDQDMATRL------KPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRF 2726
Query: 75 LEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLALF 134
LE Q TGGLVD + +A+++G + ++L P K++
Sbjct: 2727 LEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYK 2786
Query: 135 QAIGKEVVDRALGQSWLE-VQLATGGLVDP 163
AI + +V+ G LE +++ GL P
Sbjct: 2787 DAINRSMVEDITGLRLLEAASVSSKGLPSP 2816
Score = 34.7 bits (78), Expect = 2.5
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 6/96 (6%)
Query: 2044 ISDQKHMRKRFVDPNTQEKVSYRELQE-RCRPQEDTGWVLFPVNKAARDSEHIDDETRRA 2102
I D+K RK D Q+K Y +LQ+ R +E+ GW KA ++ E+ + R
Sbjct: 1118 IEDEKRRRKSVEDRFDQQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVL 1177
Query: 2103 LEAE-----QVEITVGRFRGQKPTLWALLNSEYVTE 2133
L+ E + E + + R + L ++Y TE
Sbjct: 1178 LQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETE 1213
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 261 bits (667), Expect = 1e-68
Identities = 208/698 (29%), Positives = 339/698 (48%), Gaps = 70/698 (10%)
Query: 1407 SARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVA-LRAMKVPVSTGR---F 1462
++R V YQ C+ E +L PL + D HT V L+ K PV +
Sbjct: 1992 NSRPPVRYQDN----ACEMELVKVLTPLEIAKNKQYDMHTEVTTLKQEKNPVPSAEEWML 2047
Query: 1463 KGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVTALVEAAERQPLQATFR 1522
+GC S L +++ E A ++R + F+
Sbjct: 2048 EGCRAS-GGLKKGDFLKKGLEPETFQNFDGDHACSVRDD----------------EFKFQ 2090
Query: 1523 GLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLEGGNFIAGVLIQGTQ 1582
GLR V+AR L A+L+ +T+++L G TV+EV + ++ + L IAG+ ++ T+
Sbjct: 2091 GLRHTVTARQLVEAKLLDMRTIEQLRLGLKTVEEVQK--TLNKFLTKATSIAGLYLESTK 2148
Query: 1583 ERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFKAGMFGKETYVKL 1642
E++S A R I+ AL LEAQAATGFIIDP + +VE+A G+ E ++L
Sbjct: 2149 EKISFASAAERIIIDKMVALAFLEAQAATGFIIDPISGQTYSVEDAVLKGVVDPEFRIRL 2208
Query: 1643 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGIIDPVHSHRVPVD 1702
L AE+A GY+ Y+ + +S+FQAM+ ++ R+ G +LEAQIA+GG+IDPV RVP +
Sbjct: 2209 LEAEKAAVGYS--YSSKTLSVFQAMENRMLDRQKGKHILEAQIASGGVIDPVRGIRVPPE 2266
Query: 1703 VAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLYLLQIIKK 1762
+A + G + + + L +PS +T+ F +PN + L Y +LL CV D E+ +L ++
Sbjct: 2267 IALQQGLLNNAILQFLHEPSSNTRVFPNPNNKQALYYSELLRMCVFDVESQCFLFPFGER 2326
Query: 1763 GENYVYINEATR-HVLQSRTAKMRV--GRFADQVVS---FWDLLSSPYFTEDRKRELIQE 1816
+ + + + R V+ ++T F ++ + +L Y + ++ +
Sbjct: 2327 NISNLNVKKTHRISVVDTKTGSELTVYEAFQRNLIEKSIYLELSGQQY--QWKEAMFFES 2384
Query: 1817 YGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIR----GEVT---AADLFNSRVIDQKT 1869
YG S L + I E Q I A ++ G +T AD SR++ +K
Sbjct: 2385 YGHSSHMLTDTKTGLHFNINEAIEQGT-IDKALVKKYQEGLITLTELADSLLSRLVPKKD 2443
Query: 1870 LHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFATW 1929
LH+ +AG + ++ E +S+ +ASR+ L+ A
Sbjct: 2444 LHS-------------------------PVAGYWLTASGERISVLKASRRNLVDRITALR 2478
Query: 1930 LLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTIPL 1989
LEAQ +TG ++DP T +K V EA+ GLV+E ++L + E TG P T + +
Sbjct: 2479 CLEAQVSTGGIIDPLTGKKYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPITNKMMSV 2538
Query: 1990 FQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQKH 2049
+A+ +I K +R LE Q TGG+I+PQ H RL +E A + G + I + DQK
Sbjct: 2539 VEAVNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATKLKDQKS 2598
Query: 2050 MRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNK 2087
+ + P T+ K++Y+E E+ TG L V++
Sbjct: 2599 YVRNIICPQTKRKLTYKEALEKADFDFHTGLKLLEVSE 2636
Score = 255 bits (651), Expect = 9e-67
Identities = 187/570 (32%), Positives = 303/570 (53%), Gaps = 34/570 (5%)
Query: 560 FSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPG 619
F GLR TVT +L++A+++D E+L G T ++V + ++L IAGL L
Sbjct: 2089 FQGLRHTVTARQLVEAKLLDMRTIEQLRLGLKTVEEVQK--TLNKFLTKATSIAGLYLES 2146
Query: 620 SQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFA 679
++E++S A + ++ AL LEAQAATGFIIDP + + +SVE+A+ V+ P+
Sbjct: 2147 TKEKISFASAAERIIIDKMVALAFLEAQAATGFIIDPISGQTYSVEDAVLKGVVDPEFRI 2206
Query: 680 KLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVP 739
+LL AE+A GY+ Y+ + +S+FQAM+ ++ R+ G +LEAQIA+GGVIDPV RVP
Sbjct: 2207 RLLEAEKAAVGYS--YSSKTLSVFQAMENRMLDRQKGKHILEAQIASGGVIDPVRGIRVP 2264
Query: 740 VDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLS 799
++A ++G + + L +PS +T+ F +PN + L Y +LL CV D E+ +L P
Sbjct: 2265 PEIALQQGLLNNAILQFLHEPSSNTRVFPNPNNKQALYYSELLRMCVFDVESQCFLFPFG 2324
Query: 800 STQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREV 859
+ + ++ + ++ K G EL E F +R L+ + E+
Sbjct: 2325 ERN--ISNLNVKKTHRISVVDTKTGS---------ELTVYEAF----QRNLIEKSIYLEL 2369
Query: 860 TLGQVAKLLEA---ETQRQADIMLPALRSRV--TVHQLLEAGIIDQQLLDQVLAGTIS-- 912
+ GQ + EA E+ + ML ++ + +++ +E G ID+ L+ + G I+
Sbjct: 2370 S-GQQYQWKEAMFFESYGHSSHMLTDTKTGLHFNINEAIEQGTIDKALVKKYQEGLITLT 2428
Query: 913 --PEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAAT 970
++LL ++ L V G L SG+R+S+ +A R+ L+ AL LEAQ +T
Sbjct: 2429 ELADSLLSRLVPKKDLHS--PVAGYWLTASGERISVLKASRRNLVDRITALRCLEAQVST 2486
Query: 971 GTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGL 1030
G I+DP + + V EA+ RG+V +L++ E I G P + K +SV +A+ +
Sbjct: 2487 GGIIDPLTGKKYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPITNKMMSVVEAVNANI 2546
Query: 1031 IPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETAL---SSSSETFPTP 1087
I E R LE Q TGG+I+P H L + A+Q G +D + T L S P
Sbjct: 2547 INKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATKLKDQKSYVRNIICP 2606
Query: 1088 DGQGRTSYAQLLEECPRDETSGLHLLPLPE 1117
+ + +Y + LE+ D +GL LL + E
Sbjct: 2607 QTKRKLTYKEALEKADFDFHTGLKLLEVSE 2636
Score = 224 bits (571), Expect = 2e-57
Identities = 167/564 (29%), Positives = 277/564 (49%), Gaps = 22/564 (3%)
Query: 1198 GPRGEVPAVWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSG 1257
G R V A L++A ++ T+E L G ++ +V Q + L +AG+ L+ +
Sbjct: 2091 GLRHTVTARQLVEAKLLDMRTIEQLRLGLKTVEEV--QKTLNKFLTKATSIAGLYLESTK 2148
Query: 1258 AKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQL 1317
K S A A ++ + LEAQ A+GF++DP++ Q SVEDAV G+V E +L
Sbjct: 2149 EKISFASAAERIIIDKMVALAFLEAQAATGFIIDPISGQTYSVEDAVLKGVVDPEFRIRL 2208
Query: 1318 GQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQA 1377
+AE+AA GY YS +LS++QAME ++ + +G +L+ Q+A+GGV+DPV G+ +P
Sbjct: 2209 LEAEKAAVGYS--YSSKTLSVFQAMENRMLDRQKGKHILEAQIASGGVIDPVRGIRVPPE 2266
Query: 1378 AACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSD 1437
A + GLL+ Q L + + F +P+ + + Y +L CV D E+ L P
Sbjct: 2267 IALQQGLLNNAILQFLHEPSSNTRVFPNPNNKQALYYSELLRMCVFDVESQCFLFPFGER 2326
Query: 1438 TVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAA 1497
+ + + R V TG +L + E + + + L SG+
Sbjct: 2327 NISNL--NVKKTHRISVVDTKTGS---------ELTVYEAFQRNLIEKSIYLELSGQQYQ 2375
Query: 1498 LRQVVSAVTALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEV 1557
++ A+ L T GL ++ + I + + + +G T+ E+
Sbjct: 2376 WKE---AMFFESYGHSSHMLTDTKTGLHFNIN--EAIEQGTIDKALVKKYQEGLITLTEL 2430
Query: 1558 AE--MDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFII 1615
A+ + + + + +AG + + ER+S+ +A RR+++ TAL LEAQ +TG II
Sbjct: 2431 ADSLLSRLVPKKDLHSPVAGYWLTASGERISVLKASRRNLVDRITALRCLEAQVSTGGII 2490
Query: 1616 DPAENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVRE 1675
DP +K V EA G+ + +L E +TG P T + +S+ +A+ ++I +E
Sbjct: 2491 DPLTGKKYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPITNKMMSVVEAVNANIINKE 2550
Query: 1676 HGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHE 1735
GIR LE Q TGG+I+P R+ ++ A + G D + L D + P T
Sbjct: 2551 MGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATKLKDQKSYVRNIICPQTKR 2610
Query: 1736 NLTYLQLLERCVEDPETGLYLLQI 1759
LTY + LE+ D TGL LL++
Sbjct: 2611 KLTYKEALEKADFDFHTGLKLLEV 2634
Score = 223 bits (567), Expect = 5e-57
Identities = 172/596 (28%), Positives = 281/596 (47%), Gaps = 71/596 (11%)
Query: 1846 KVAAIRGEVTAADLFNSRVIDQKTLHTLRVG-RTGGQALSTLECVKPYLEGSDCIAGVTV 1904
K +R VTA L ++++D +T+ LR+G +T + TL +L + IAG+ +
Sbjct: 2088 KFQGLRHTVTARQLVEAKLLDMRTIEQLRLGLKTVEEVQKTLN---KFLTKATSIAGLYL 2144
Query: 1905 PSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEEL 1964
ST+E +S A+ + +I A LEAQAATGF++DP + Q SV++AV G+V+ E
Sbjct: 2145 ESTKEKISFASAAERIIIDKMVALAFLEAQAATGFIIDPISGQTYSVEDAVLKGVVDPEF 2204
Query: 1965 RERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHR 2024
R RLL+AE+AA GY + T+ +FQAM+ +++++ + +LE Q+A+GGVIDP R
Sbjct: 2205 RIRLLEAEKAAVGYS--YSSKTLSVFQAMENRMLDRQKGKHILEAQIASGGVIDPVRGIR 2262
Query: 2025 LPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFP 2084
+P E A ++G L+ I + + + F +PN ++ + Y EL C ++ LFP
Sbjct: 2263 VPPEIALQQGLLNNAILQFLHEPSSNTRVFPNPNNKQALYYSELLRMCVFDVESQCFLFP 2322
Query: 2085 VNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYR 2144
+ + ++ KK + +
Sbjct: 2323 FGERNISNLNV---------------------------------------KKTHRISVVD 2343
Query: 2145 THTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETG- 2203
T T L LIEK + +L G + Q + S + ML D +TG
Sbjct: 2344 TKTGSELTVYEAFQRNLIEK----SIYLELSGQQYQWKEAMFFESYGHSSHMLTDTKTGL 2399
Query: 2204 -----RSTTQELMEDDRVKRYLEG-------TSCIAGVLVPAKD---------QPGRQEK 2242
+ Q ++ VK+Y EG + LVP KD E+
Sbjct: 2400 HFNINEAIEQGTIDKALVKKYQEGLITLTELADSLLSRLVPKKDLHSPVAGYWLTASGER 2459
Query: 2243 MSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLS 2302
+S+ +A + ++ TAL LEAQ +TG +IDP+ + V E + G+V ++L
Sbjct: 2460 ISVLKASRRNLVDRITALRCLEAQVSTGGIIDPLTGKKYRVAEALHRGLVDEGFAQQLRQ 2519
Query: 2303 AERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVA 2362
E +TG P T + +S+ +A+ ++I +E GIR LE Q TGG+I+P R+ ++ A
Sbjct: 2520 CELVITGIGHPITNKMMSVVEAVNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEA 2579
Query: 2363 YRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLA 2418
+ G D + L D + P T LTY + L + D TGL +L+++
Sbjct: 2580 LQVGIIDVLIATKLKDQKSYVRNIICPQTKRKLTYKEALEKADFDFHTGLKLLEVS 2635
Score = 216 bits (549), Expect = 6e-55
Identities = 177/575 (30%), Positives = 276/575 (48%), Gaps = 38/575 (6%)
Query: 235 FRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLLP 294
F+ + V+A +L+E +LD + ++ LR G +V + + ++L S+AG+ L
Sbjct: 2089 FQGLRHTVTARQLVEAKLLDMRTIEQLRLGLKTVEEV--QKTLNKFLTKATSIAGLYLES 2146
Query: 295 EGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELHE 354
K SF AA ++ AL LEAQAAT ++DPI+GQ V++AV G+V PE
Sbjct: 2147 TKEKISFASAAERIIIDKMVALAFLEAQAATGFIIDPISGQTYSVEDAVLKGVVDPEFRI 2206
Query: 355 QLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLP 414
+LL AE+A G+ +S + +FQAM+ ++DR +L+AQ+A+GG++ P R +R+P
Sbjct: 2207 RLLEAEKAAVGY--SYSSKTLSVFQAMENRMLDRQKGKHILEAQIASGGVIDPVRGIRVP 2264
Query: 415 LEAALRCGCLDEDTQRQLSQAGSF-----SDGTHGGLRYEQLLALCVTDPETGLAFLPLS 469
E AL+ G L+ + L + S + L Y +LL +CV D E+ P
Sbjct: 2265 PEIALQQGLLNNAILQFLHEPSSNTRVFPNPNNKQALYYSELLRMCVFDVESQCFLFPF- 2323
Query: 470 GGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAI-SSEQRAMLA 528
GE T + T T G ++++E I S +
Sbjct: 2324 -----GERNISNLNVKKTHRISVVDTKT-------GSELTVYEAFQRNLIEKSIYLELSG 2371
Query: 529 QQYQEGTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLEH 588
QQYQ + S L T +GL + E ++ ID+ L ++ +
Sbjct: 2372 QQYQWKEAMFFESYGHSSHMLTD-------TKTGLHFNI--NEAIEQGTIDKALVKKYQE 2422
Query: 589 GQATAKDVG-SLAS---AQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILL 644
G T ++ SL S ++ L +AG L S ER+S+ +A + L+ TAL L
Sbjct: 2423 GLITLTELADSLLSRLVPKKDLHSP--VAGYWLTASGERISVLKASRRNLVDRITALRCL 2480
Query: 645 EAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQ 704
EAQ +TG IIDP K + V EAL ++ +L E +TG P T + +S+ +
Sbjct: 2481 EAQVSTGGIIDPLTGKKYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPITNKMMSVVE 2540
Query: 705 AMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDT 764
A+ +I +E GIR LE Q TGG+I+P R+ ++ A + G D ++ L D
Sbjct: 2541 AVNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATKLKDQKSYV 2600
Query: 765 KGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLS 799
+ P T LTY + LE+ D TGL LL +S
Sbjct: 2601 RNIICPQTKRKLTYKEALEKADFDFHTGLKLLEVS 2635
Score = 170 bits (431), Expect = 3e-41
Identities = 138/524 (26%), Positives = 246/524 (46%), Gaps = 71/524 (13%)
Query: 874 RQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVG 933
R + LR VT QL+EA ++D + ++Q+ G + E + + ++L ++
Sbjct: 2083 RDDEFKFQGLRHTVTARQLVEAKLLDMRTIEQLRLGLKTVEEV--QKTLNKFLTKATSIA 2140
Query: 934 GVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVV 993
G+ L + +++S A + ++ VALA LEAQAATG I+DP S ++ SV++AV +GVV
Sbjct: 2141 GLYLESTKEKISFASAAERIIIDKMVALAFLEAQAATGFIIDPISGQTYSVEDAVLKGVV 2200
Query: 994 GPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPT 1053
PE RL AE A G+ +S K +SVFQAM+ ++ ++ +LEAQ+A+GG+IDP
Sbjct: 2201 DPEFRIRLLEAEKAAVGYS--YSSKTLSVFQAMENRMLDRQKGKHILEAQIASGGVIDPV 2258
Query: 1054 SHHHLPMPVAIQRGYVDQEMETAL---SSSSETFPTPDGQGRTSYAQLLEECPRDETSGL 1110
+P +A+Q+G ++ + L SS++ FP P+ + Y++LL C D S
Sbjct: 2259 RGIRVPPEIALQQGLLNNAILQFLHEPSSNTRVFPNPNNKQALYYSELLRMCVFDVESQC 2318
Query: 1111 HLLPLPE--------------------SAPALPTEEQVQRSL-----------------Q 1133
L P E + L E QR+L +
Sbjct: 2319 FLFPFGERNISNLNVKKTHRISVVDTKTGSELTVYEAFQRNLIEKSIYLELSGQQYQWKE 2378
Query: 1134 AVPGAKDGTS---LWDLLSSCHFTEEQR-------RGLLEDVQEGRTTVPQLLASVQRWV 1183
A+ G S L D + HF + + L++ QEG T+ +L S+
Sbjct: 2379 AMFFESYGHSSHMLTDTKTGLHFNINEAIEQGTIDKALVKKYQEGLITLTELADSLL--- 2435
Query: 1184 QETKLLAQARVMVPGPRGEVPAVWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLW 1243
++L+ + + P V WL +G E ++ S + ++ CL
Sbjct: 2436 --SRLVPKKDLHSP-----VAGYWLTASG-------ERISVLKASRRNLVDRITALRCLE 2481
Query: 1244 GTGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDA 1303
G++ +G K +A+A+ GL+ G Q+L + ++ + P+ N+ +SV +A
Sbjct: 2482 AQVSTGGIIDPLTGKKYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPITNKMMSVVEA 2541
Query: 1304 VKVGLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLV 1347
V ++ +E+ + + + G +P + LS+ +A++ G++
Sbjct: 2542 VNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGII 2585
Score = 166 bits (419), Expect = 7e-40
Identities = 103/302 (34%), Positives = 171/302 (56%), Gaps = 9/302 (2%)
Query: 2702 RLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIA 2761
R + F+GLR V+A +L + +L T+ L G KT++EV + ++ ++L + IA
Sbjct: 2083 RDDEFKFQGLRHTVTARQLVEAKLLDMRTIEQLRLGLKTVEEVQK--TLNKFLTKATSIA 2140
Query: 2762 GVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAV 2821
G+ + + +EK+S A + ++ AL LEAQAATGF+IDP+ SVE+AV
Sbjct: 2141 GLYLEST-----KEKISFASAAERIIIDKMVALAFLEAQAATGFIIDPISGQTYSVEDAV 2195
Query: 2822 AAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGG 2881
GVV E + +LL AE+A GY+ Y+ + +S+FQAM+ ++ R+ G +LEAQIA+GG
Sbjct: 2196 LKGVVDPEFRIRLLEAEKAAVGYS--YSSKTLSVFQAMENRMLDRQKGKHILEAQIASGG 2253
Query: 2882 VIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPD 2941
VIDPV RVP ++A ++G + + + L +PS +T+ F +PN + L Y +LLR CV D
Sbjct: 2254 VIDPVRGIRVPPEIALQQGLLNNAILQFLHEPSSNTRVFPNPNNKQALYYSELLRMCVFD 2313
Query: 2942 PDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDR 3001
++ ++ R + + + R ++ D + + ++ E Y E+S +
Sbjct: 2314 VESQCFLFPFGERNISNLNVKKTHRISVVDTKTGSELTVYEAFQRNLIEKSIYLELSGQQ 2373
Query: 3002 RQ 3003
Q
Sbjct: 2374 YQ 2375
Score = 166 bits (419), Expect = 7e-40
Identities = 103/302 (34%), Positives = 171/302 (56%), Gaps = 9/302 (2%)
Query: 3236 RLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIA 3295
R + F+GLR V+A +L + +L T+ L G KT++EV + ++ ++L + IA
Sbjct: 2083 RDDEFKFQGLRHTVTARQLVEAKLLDMRTIEQLRLGLKTVEEVQK--TLNKFLTKATSIA 2140
Query: 3296 GVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAV 3355
G+ + + +EK+S A + ++ AL LEAQAATGF+IDP+ SVE+AV
Sbjct: 2141 GLYLEST-----KEKISFASAAERIIIDKMVALAFLEAQAATGFIIDPISGQTYSVEDAV 2195
Query: 3356 AAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGG 3415
GVV E + +LL AE+A GY+ Y+ + +S+FQAM+ ++ R+ G +LEAQIA+GG
Sbjct: 2196 LKGVVDPEFRIRLLEAEKAAVGYS--YSSKTLSVFQAMENRMLDRQKGKHILEAQIASGG 2253
Query: 3416 VIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPD 3475
VIDPV RVP ++A ++G + + + L +PS +T+ F +PN + L Y +LLR CV D
Sbjct: 2254 VIDPVRGIRVPPEIALQQGLLNNAILQFLHEPSSNTRVFPNPNNKQALYYSELLRMCVFD 2313
Query: 3476 PDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDR 3535
++ ++ R + + + R ++ D + + ++ E Y E+S +
Sbjct: 2314 VESQCFLFPFGERNISNLNVKKTHRISVVDTKTGSELTVYEAFQRNLIEKSIYLELSGQQ 2373
Query: 3536 RQ 3537
Q
Sbjct: 2374 YQ 2375
Score = 166 bits (419), Expect = 7e-40
Identities = 103/302 (34%), Positives = 171/302 (56%), Gaps = 9/302 (2%)
Query: 3770 RLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIA 3829
R + F+GLR V+A +L + +L T+ L G KT++EV + ++ ++L + IA
Sbjct: 2083 RDDEFKFQGLRHTVTARQLVEAKLLDMRTIEQLRLGLKTVEEVQK--TLNKFLTKATSIA 2140
Query: 3830 GVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAV 3889
G+ + + +EK+S A + ++ AL LEAQAATGF+IDP+ SVE+AV
Sbjct: 2141 GLYLEST-----KEKISFASAAERIIIDKMVALAFLEAQAATGFIIDPISGQTYSVEDAV 2195
Query: 3890 AAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGG 3949
GVV E + +LL AE+A GY+ Y+ + +S+FQAM+ ++ R+ G +LEAQIA+GG
Sbjct: 2196 LKGVVDPEFRIRLLEAEKAAVGYS--YSSKTLSVFQAMENRMLDRQKGKHILEAQIASGG 2253
Query: 3950 VIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPD 4009
VIDPV RVP ++A ++G + + + L +PS +T+ F +PN + L Y +LLR CV D
Sbjct: 2254 VIDPVRGIRVPPEIALQQGLLNNAILQFLHEPSSNTRVFPNPNNKQALYYSELLRMCVFD 2313
Query: 4010 PDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDR 4069
++ ++ R + + + R ++ D + + ++ E Y E+S +
Sbjct: 2314 VESQCFLFPFGERNISNLNVKKTHRISVVDTKTGSELTVYEAFQRNLIEKSIYLELSGQQ 2373
Query: 4070 RQ 4071
Q
Sbjct: 2374 YQ 2375
Score = 166 bits (419), Expect = 7e-40
Identities = 103/302 (34%), Positives = 171/302 (56%), Gaps = 9/302 (2%)
Query: 4304 RLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIA 4363
R + F+GLR V+A +L + +L T+ L G KT++EV + ++ ++L + IA
Sbjct: 2083 RDDEFKFQGLRHTVTARQLVEAKLLDMRTIEQLRLGLKTVEEVQK--TLNKFLTKATSIA 2140
Query: 4364 GVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAV 4423
G+ + + +EK+S A + ++ AL LEAQAATGF+IDP+ SVE+AV
Sbjct: 2141 GLYLEST-----KEKISFASAAERIIIDKMVALAFLEAQAATGFIIDPISGQTYSVEDAV 2195
Query: 4424 AAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGG 4483
GVV E + +LL AE+A GY+ Y+ + +S+FQAM+ ++ R+ G +LEAQIA+GG
Sbjct: 2196 LKGVVDPEFRIRLLEAEKAAVGYS--YSSKTLSVFQAMENRMLDRQKGKHILEAQIASGG 2253
Query: 4484 VIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPD 4543
VIDPV RVP ++A ++G + + + L +PS +T+ F +PN + L Y +LLR CV D
Sbjct: 2254 VIDPVRGIRVPPEIALQQGLLNNAILQFLHEPSSNTRVFPNPNNKQALYYSELLRMCVFD 2313
Query: 4544 PDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDR 4603
++ ++ R + + + R ++ D + + ++ E Y E+S +
Sbjct: 2314 VESQCFLFPFGERNISNLNVKKTHRISVVDTKTGSELTVYEAFQRNLIEKSIYLELSGQQ 2373
Query: 4604 RQ 4605
Q
Sbjct: 2374 YQ 2375
Score = 161 bits (408), Expect = 1e-38
Identities = 97/296 (32%), Positives = 166/296 (56%), Gaps = 9/296 (3%)
Query: 2174 FQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPA 2233
FQG+R +TA +L+ + ++ ++ L G T +E+ + + ++L + IAG+ + +
Sbjct: 2089 FQGLRHTVTARQLVEAKLLDMRTIEQLRLGLKTVEEVQKT--LNKFLTKATSIAGLYLES 2146
Query: 2234 KDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVG 2293
+EK+S A + ++ AL LEAQAATGF+IDP+ SVE+ V GVV
Sbjct: 2147 T-----KEKISFASAAERIIIDKMVALAFLEAQAATGFIIDPISGQTYSVEDAVLKGVVD 2201
Query: 2294 SEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVH 2353
E + +LL AE+A GY+ Y+ + +S+FQAM+ ++ R+ G +LEAQIA+GGVIDPV
Sbjct: 2202 PEFRIRLLEAEKAAVGYS--YSSKTLSVFQAMENRMLDRQKGKHILEAQIASGGVIDPVR 2259
Query: 2354 SHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLY 2413
RVP ++A ++G + + + L +PS +T+ F +PN + L Y +LLR CV D ++ +
Sbjct: 2260 GIRVPPEIALQQGLLNNAILQFLHEPSSNTRVFPNPNNKQALYYSELLRMCVFDVESQCF 2319
Query: 2414 MLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQ 2469
+ R + + + R ++ D + + ++ E Y E+S + Q
Sbjct: 2320 LFPFGERNISNLNVKKTHRISVVDTKTGSELTVYEAFQRNLIEKSIYLELSGQQYQ 2375
Score = 158 bits (400), Expect = 1e-37
Identities = 93/243 (38%), Positives = 148/243 (60%), Gaps = 9/243 (3%)
Query: 4838 RLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIA 4897
R + F+GLR V+A +L + +L T+ L G KT++EV + ++ ++L + IA
Sbjct: 2083 RDDEFKFQGLRHTVTARQLVEAKLLDMRTIEQLRLGLKTVEEVQK--TLNKFLTKATSIA 2140
Query: 4898 GVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAV 4957
G+ + + +EK+S A + ++ AL LEAQAATGF+IDP+ SVE+AV
Sbjct: 2141 GLYLEST-----KEKISFASAAERIIIDKMVALAFLEAQAATGFIIDPISGQTYSVEDAV 2195
Query: 4958 AAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGG 5017
GVV E + +LL AE+A GY+ Y+ + +S+FQAM+ ++ R+ G +LEAQIA+GG
Sbjct: 2196 LKGVVDPEFRIRLLEAEKAAVGYS--YSSKTLSVFQAMENRMLDRQKGKHILEAQIASGG 2253
Query: 5018 VIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLD 5077
VIDPV RVP ++A ++G + + + L +PS +T+ F +PN + L Y +LL+ D
Sbjct: 2254 VIDPVRGIRVPPEIALQQGLLNNAILQFLHEPSSNTRVFPNPNNKQALYYSELLRMCVFD 2313
Query: 5078 PET 5080
E+
Sbjct: 2314 VES 2316
Score = 155 bits (391), Expect = 1e-36
Identities = 124/417 (29%), Positives = 195/417 (46%), Gaps = 53/417 (12%)
Query: 39 QARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKA 98
+A SIAG+Y+E++ + S +A E+ ++ + A LEAQAATG ++D GQ V A
Sbjct: 2135 KATSIAGLYLESTKEKISFASAAERIIIDKMVALAFLEAQAATGFIIDPISGQTYSVEDA 2194
Query: 99 LQQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATG 158
+ +G+V E + +LL AE+A GY Y + L++FQA+ ++DR G+ LE Q+A+G
Sbjct: 2195 VLKGVVDPEFRIRLLEAEKAAVGY--SYSSKTLSVFQAMENRMLDRQKGKHILEAQIASG 2252
Query: 159 GLVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERC 218
G++DP +G+ V PE A QGLL+ L EP + F NPN + L Y +LL C
Sbjct: 2253 GVIDPVRGIRVPPEIALQQGLLNNAILQFLH--EPSSNTRVFPNPNNKQALYYSELLRMC 2310
Query: 219 VRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVR 278
V S L P G + + + R++ VD +E+
Sbjct: 2311 VFDVESQCFLFPF-------------------GERNISNLNVKKTHRISVVDTKTGSELT 2351
Query: 279 RYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLW 338
Y ++ +KS + + A+ ++H L D TG
Sbjct: 2352 VYEAFQRNLI---------EKSIYLELSGQQYQWKEAMFFESYGHSSHMLTDTKTGLHFN 2402
Query: 339 VDEAVRAGLVS--------------PELHEQLLV-------AEQAVTGHHDPFSGSQIPL 377
++EA+ G + EL + LL V G+ SG +I +
Sbjct: 2403 INEAIEQGTIDKALVKKYQEGLITLTELADSLLSRLVPKKDLHSPVAGYWLTASGERISV 2462
Query: 378 FQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLSQ 434
+A ++ LVDR ALR L+AQ++TGG++ P + + AL G +DE +QL Q
Sbjct: 2463 LKASRRNLVDRITALRCLEAQVSTGGIIDPLTGKKYRVAEALHRGLVDEGFAQQLRQ 2519
Score = 104 bits (259), Expect = 3e-21
Identities = 70/219 (31%), Positives = 109/219 (49%), Gaps = 16/219 (7%)
Query: 4886 VKRYLEGTSCIAGV-------LVPAKDQ---------PGRQEKMSIYQAMWKGVLRPGTA 4929
VK+Y EG + + LVP KD E++S+ +A + ++ TA
Sbjct: 2417 VKKYQEGLITLTELADSLLSRLVPKKDLHSPVAGYWLTASGERISVLKASRRNLVDRITA 2476
Query: 4930 LVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQI 4989
L LEAQ +TG +IDP+ + V EA+ G+V ++L E +TG P T + +
Sbjct: 2477 LRCLEAQVSTGGIIDPLTGKKYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPITNKMM 2536
Query: 4990 SLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADP 5049
S+ +A+ ++I +E GIR LE Q TGG+I+P R+ ++ A + G D + L D
Sbjct: 2537 SVVEAVNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATKLKDQ 2596
Query: 5050 SDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLS 5088
+ P T LTY + L++A D TGL L +S
Sbjct: 2597 KSYVRNIICPQTKRKLTYKEALEKADFDFHTGLKLLEVS 2635
Score = 99.8 bits (247), Expect = 6e-20
Identities = 68/219 (31%), Positives = 109/219 (49%), Gaps = 16/219 (7%)
Query: 2750 VKRYLEGTSCIAGV-------LVPAKDQ---------PGRQEKMSIYQAMWKGVLRPGTA 2793
VK+Y EG + + LVP KD E++S+ +A + ++ TA
Sbjct: 2417 VKKYQEGLITLTELADSLLSRLVPKKDLHSPVAGYWLTASGERISVLKASRRNLVDRITA 2476
Query: 2794 LVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQI 2853
L LEAQ +TG +IDP+ + V EA+ G+V ++L E +TG P T + +
Sbjct: 2477 LRCLEAQVSTGGIIDPLTGKKYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPITNKMM 2536
Query: 2854 SLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADP 2913
S+ +A+ ++I +E GIR LE Q TGG+I+P R+ ++ A + G D + L D
Sbjct: 2537 SVVEAVNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATKLKDQ 2596
Query: 2914 SDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLA 2952
+ P T LTY + L + D TGL +L+++
Sbjct: 2597 KSYVRNIICPQTKRKLTYKEALEKADFDFHTGLKLLEVS 2635
Score = 99.8 bits (247), Expect = 6e-20
Identities = 68/219 (31%), Positives = 109/219 (49%), Gaps = 16/219 (7%)
Query: 3284 VKRYLEGTSCIAGV-------LVPAKDQ---------PGRQEKMSIYQAMWKGVLRPGTA 3327
VK+Y EG + + LVP KD E++S+ +A + ++ TA
Sbjct: 2417 VKKYQEGLITLTELADSLLSRLVPKKDLHSPVAGYWLTASGERISVLKASRRNLVDRITA 2476
Query: 3328 LVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQI 3387
L LEAQ +TG +IDP+ + V EA+ G+V ++L E +TG P T + +
Sbjct: 2477 LRCLEAQVSTGGIIDPLTGKKYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPITNKMM 2536
Query: 3388 SLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADP 3447
S+ +A+ ++I +E GIR LE Q TGG+I+P R+ ++ A + G D + L D
Sbjct: 2537 SVVEAVNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATKLKDQ 2596
Query: 3448 SDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLA 3486
+ P T LTY + L + D TGL +L+++
Sbjct: 2597 KSYVRNIICPQTKRKLTYKEALEKADFDFHTGLKLLEVS 2635
Score = 99.8 bits (247), Expect = 6e-20
Identities = 68/219 (31%), Positives = 109/219 (49%), Gaps = 16/219 (7%)
Query: 3818 VKRYLEGTSCIAGV-------LVPAKDQ---------PGRQEKMSIYQAMWKGVLRPGTA 3861
VK+Y EG + + LVP KD E++S+ +A + ++ TA
Sbjct: 2417 VKKYQEGLITLTELADSLLSRLVPKKDLHSPVAGYWLTASGERISVLKASRRNLVDRITA 2476
Query: 3862 LVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQI 3921
L LEAQ +TG +IDP+ + V EA+ G+V ++L E +TG P T + +
Sbjct: 2477 LRCLEAQVSTGGIIDPLTGKKYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPITNKMM 2536
Query: 3922 SLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADP 3981
S+ +A+ ++I +E GIR LE Q TGG+I+P R+ ++ A + G D + L D
Sbjct: 2537 SVVEAVNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATKLKDQ 2596
Query: 3982 SDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLA 4020
+ P T LTY + L + D TGL +L+++
Sbjct: 2597 KSYVRNIICPQTKRKLTYKEALEKADFDFHTGLKLLEVS 2635
Score = 99.8 bits (247), Expect = 6e-20
Identities = 68/219 (31%), Positives = 109/219 (49%), Gaps = 16/219 (7%)
Query: 4352 VKRYLEGTSCIAGV-------LVPAKDQ---------PGRQEKMSIYQAMWKGVLRPGTA 4395
VK+Y EG + + LVP KD E++S+ +A + ++ TA
Sbjct: 2417 VKKYQEGLITLTELADSLLSRLVPKKDLHSPVAGYWLTASGERISVLKASRRNLVDRITA 2476
Query: 4396 LVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQI 4455
L LEAQ +TG +IDP+ + V EA+ G+V ++L E +TG P T + +
Sbjct: 2477 LRCLEAQVSTGGIIDPLTGKKYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPITNKMM 2536
Query: 4456 SLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADP 4515
S+ +A+ ++I +E GIR LE Q TGG+I+P R+ ++ A + G D + L D
Sbjct: 2537 SVVEAVNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATKLKDQ 2596
Query: 4516 SDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLA 4554
+ P T LTY + L + D TGL +L+++
Sbjct: 2597 KSYVRNIICPQTKRKLTYKEALEKADFDFHTGLKLLEVS 2635
Score = 87.0 bits (214), Expect = 4e-16
Identities = 57/195 (29%), Positives = 99/195 (50%), Gaps = 2/195 (1%)
Query: 35 PPRPQARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLP 94
P + +AG ++ ASG+ SV A + L+ LEAQ +TGG++D G+
Sbjct: 2440 PKKDLHSPVAGYWLTASGERISVLKASRRNLVDRITALRCLEAQVSTGGIIDPLTGKKYR 2499
Query: 95 VSKALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQ 154
V++AL +GLV ++L E TG P + +++ +A+ ++++ +G LE Q
Sbjct: 2500 VAEALHRGLVDEGFAQQLRQCELVITGIGHPITNKMMSVVEAVNANIINKEMGIRCLEFQ 2559
Query: 155 LATGGLVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQL 214
TGGL++P ++ E A G++D KL + + ++ + P T +LTY +
Sbjct: 2560 YLTGGLIEPQVHSRLSIEEALQVGIIDVLIATKLKDQKSYVRNI--ICPQTKRKLTYKEA 2617
Query: 215 LERCVRAPGSGLALL 229
LE+ +GL LL
Sbjct: 2618 LEKADFDFHTGLKLL 2632
Score = 59.7 bits (143), Expect = 7e-08
Identities = 98/450 (21%), Positives = 166/450 (36%), Gaps = 113/450 (25%)
Query: 44 AGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGL 103
A V S + SV+ AME +L G+ +LEAQ A+GG++D RG +P ALQQGL
Sbjct: 2214 AAVGYSYSSKTLSVFQAMENRMLDRQKGKHILEAQIASGGVIDPVRGIRVPPEIALQQGL 2273
Query: 104 VGLELKEKLLAAERATTGYPD---------------------------PYG--------- 127
+ + + L T +P+ P+G
Sbjct: 2274 LNNAILQFLHEPSSNTRVFPNPNNKQALYYSELLRMCVFDVESQCFLFPFGERNISNLNV 2333
Query: 128 -------------GEKLALFQAIGKEVVDRAL-----GQS--WLEVQL------ATGGLV 161
G +L +++A + ++++++ GQ W E ++ L
Sbjct: 2334 KKTHRISVVDTKTGSELTVYEAFQRNLIEKSIYLELSGQQYQWKEAMFFESYGHSSHMLT 2393
Query: 162 DPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCVRA 221
D G+ A QG +D+ K E G L L + L RL + L V
Sbjct: 2394 DTKTGLHFNINEAIEQGTIDKALVKKYQE---GLITLTELADSLLSRLVPKKDLHSPVAG 2450
Query: 222 ---PGSGLALLPLKITFRSMGGAVSA------------------------AELLEVGILD 254
SG + LK + R++ ++A AE L G++D
Sbjct: 2451 YWLTASGERISVLKASRRNLVDRITALRCLEAQVSTGGIIDPLTGKKYRVAEALHRGLVD 2510
Query: 255 EQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGT 314
E Q LR+ L + G+ S +A +++
Sbjct: 2511 EGFAQQLRQCELV-------------------ITGIGHPITNKMMSVVEAVNANIINKEM 2551
Query: 315 ALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQ 374
+ LE Q T L++P RL ++EA++ G++ + +L + V P + +
Sbjct: 2552 GIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATKLKDQKSYVRNIICPQTKRK 2611
Query: 375 IPLFQAMKKGLVDRPLALRLLDAQ--LATG 402
+ +A++K D L+LL+ L TG
Sbjct: 2612 LTYKEALEKADFDFHTGLKLLEVSEPLMTG 2641
Score = 43.5 bits (101), Expect = 0.005
Identities = 35/164 (21%), Positives = 70/164 (42%), Gaps = 5/164 (3%)
Query: 2752 RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVR 2811
R LE G++ P + K + +A+ +G++ G A L + + + P+
Sbjct: 2478 RCLEAQVSTGGIIDPLTGK-----KYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPIT 2532
Query: 2812 NLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIR 2871
N +SV EAV A ++ E+ + L + G +P ++S+ +A+Q +I +
Sbjct: 2533 NKMMSVVEAVNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATK 2592
Query: 2872 LLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSD 2915
L + + +I P ++ A + FD L + S+
Sbjct: 2593 LKDQKSYVRNIICPQTKRKLTYKEALEKADFDFHTGLKLLEVSE 2636
Score = 43.5 bits (101), Expect = 0.005
Identities = 35/164 (21%), Positives = 70/164 (42%), Gaps = 5/164 (3%)
Query: 3286 RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVR 3345
R LE G++ P + K + +A+ +G++ G A L + + + P+
Sbjct: 2478 RCLEAQVSTGGIIDPLTGK-----KYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPIT 2532
Query: 3346 NLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIR 3405
N +SV EAV A ++ E+ + L + G +P ++S+ +A+Q +I +
Sbjct: 2533 NKMMSVVEAVNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATK 2592
Query: 3406 LLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSD 3449
L + + +I P ++ A + FD L + S+
Sbjct: 2593 LKDQKSYVRNIICPQTKRKLTYKEALEKADFDFHTGLKLLEVSE 2636
Score = 43.5 bits (101), Expect = 0.005
Identities = 35/164 (21%), Positives = 70/164 (42%), Gaps = 5/164 (3%)
Query: 3820 RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVR 3879
R LE G++ P + K + +A+ +G++ G A L + + + P+
Sbjct: 2478 RCLEAQVSTGGIIDPLTGK-----KYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPIT 2532
Query: 3880 NLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIR 3939
N +SV EAV A ++ E+ + L + G +P ++S+ +A+Q +I +
Sbjct: 2533 NKMMSVVEAVNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATK 2592
Query: 3940 LLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSD 3983
L + + +I P ++ A + FD L + S+
Sbjct: 2593 LKDQKSYVRNIICPQTKRKLTYKEALEKADFDFHTGLKLLEVSE 2636
Score = 43.5 bits (101), Expect = 0.005
Identities = 35/164 (21%), Positives = 70/164 (42%), Gaps = 5/164 (3%)
Query: 4354 RYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVR 4413
R LE G++ P + K + +A+ +G++ G A L + + + P+
Sbjct: 2478 RCLEAQVSTGGIIDPLTGK-----KYRVAEALHRGLVDEGFAQQLRQCELVITGIGHPIT 2532
Query: 4414 NLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIR 4473
N +SV EAV A ++ E+ + L + G +P ++S+ +A+Q +I +
Sbjct: 2533 NKMMSVVEAVNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATK 2592
Query: 4474 LLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSD 4517
L + + +I P ++ A + FD L + S+
Sbjct: 2593 LKDQKSYVRNIICPQTKRKLTYKEALEKADFDFHTGLKLLEVSE 2636
Score = 39.7 bits (91), Expect = 0.077
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 2/118 (1%)
Query: 43 IAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQG 102
I G+ + + SV A+ ++ +G LE Q TGGL++ L + +ALQ G
Sbjct: 2524 ITGIGHPITNKMMSVVEAVNANIINKEMGIRCLEFQYLTGGLIEPQVHSRLSIEEALQVG 2583
Query: 103 LVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQ--LATG 158
++ + + KL + P KL +A+ K D G LEV L TG
Sbjct: 2584 IIDVLIATKLKDQKSYVRNIICPQTKRKLTYKEALEKADFDFHTGLKLLEVSEPLMTG 2641
>gi|33188443 microfilament and actin filament cross-linker protein
isoform b [Homo sapiens]
Length = 5938
Score = 127 bits (320), Expect = 2e-28
Identities = 107/381 (28%), Positives = 174/381 (45%), Gaps = 33/381 (8%)
Query: 61 MEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERAT- 119
M++GLL G LLE+Q GL+ G+ L + + + + L+ ++ ++L + A
Sbjct: 1 MQKGLLDQDTGLVLLESQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALA 60
Query: 120 --TGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQ 177
+ + G L++ +AI K ++ +G LE LATGG + E A HQ
Sbjct: 61 LISRLTESRG--PLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENCINLEEAFHQ 118
Query: 178 GLLDRETW-HKLSELEPGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALLPLKITFR 236
GL+ W H + E T ++PNT E++ L++RC+ SG LLP+K
Sbjct: 119 GLIS--AWLHSVLESYLRTSK-NLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAG 175
Query: 237 SM-----GGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVV 291
M G VS ++ G++D Q L E +L A G+V
Sbjct: 176 GMVSLKSGRKVSIFRAVQEGLIDRQVTVRLLEAQLFA-------------------GGIV 216
Query: 292 LLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPE 351
GH+ + +A +L+ A +L Q T ++D +TGQRL +DEAV LV+ +
Sbjct: 217 DPRTGHRLTVEEAVRHNLIDQDMACAILIRQLQTGGIIDTVTGQRLTIDEAVSNDLVAAK 276
Query: 352 LHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRL 411
+ +L + + G P SG +P+ A+++G+V LA ++L + L PA
Sbjct: 277 IALVILESLWSFMGLLWPESGEILPITDALEQGIVSTELAHKILSNRQHIKALFLPATTE 336
Query: 412 RLPLEAALRCGCLDEDTQRQL 432
L + A+ G LD D L
Sbjct: 337 ILSWKKAIESGILDRDLANNL 357
Score = 126 bits (317), Expect = 5e-28
Identities = 251/1192 (21%), Positives = 458/1192 (38%), Gaps = 171/1192 (14%)
Query: 950 MRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIA 1009
M++ LL L LLE+Q ++ P + E+LS++E + R ++ P++Y +L+ + A+A
Sbjct: 1 MQKGLLDQDTGLVLLESQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALA 60
Query: 1010 GF-RDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGY 1068
R S +SV +A++K +I ++LEA +ATGG S + + + A +G
Sbjct: 61 LISRLTESRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENCINLEEAFHQGL 120
Query: 1069 VDQEMETALSS---SSETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTE 1125
+ + + L S +S+ P+ + L++ C + SG LLP+
Sbjct: 121 ISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPV---------- 170
Query: 1126 EQVQRSLQAVPGAKDGTSLWDLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQE 1185
+Q G + ++ GR S+ R VQE
Sbjct: 171 ------------------------------KQLAGGMVSLKSGRK------VSIFRAVQE 194
Query: 1186 TKLLAQARVMVPGPRGEVPAVWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGT 1245
+ Q V + L GI+ T L + +Q A L
Sbjct: 195 GLIDRQVTV-------RLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAILIRQ 247
Query: 1246 GCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVK 1305
G++ +G + +I +AV + L+ + +LE+ + L+ P + + L + DA++
Sbjct: 248 LQTGGIIDTVTGQRLTIDEAVSNDLVAAKIALVILESLWSFMGLLWPESGEILPITDALE 307
Query: 1306 VGLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGV 1365
G+V EL+ ++ + P + LS +A+E G++ ++ L L + +
Sbjct: 308 QGIVSTELAHKILSNRQHIKALFLPATTEILSWKKAIESGILDRD-----LANNLKSICI 362
Query: 1366 VDPVHGVHLPQAAACRL----GLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERC 1421
D + + L +A + +L S + F + Q +
Sbjct: 363 PDVMPHMQLADSAEQNINPGAAVLPCSKSHPKATASQSENLLFQLMTHSYINVQNGQRLL 422
Query: 1422 VCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPVSTG-------RFKGCSVSLWDLLL 1474
+ D E L+ L S + V + + G + G S W + L
Sbjct: 423 LLDKE---LMETLTSRDEYQTSPPKVVEIGHQRQKTPEGLQESANVKISGTFSSGWTVRL 479
Query: 1475 SEYVGADKRRELV----ALCRSGRAAALRQVVSAV-----TALVEAAERQP--------- 1516
E+ + + +E G+ + S+V VE ER P
Sbjct: 480 PEFQFSSQNKEYPDREDCTTEKGKKTTVETEDSSVENPEQDLFVEQKERNPNIDALKVIN 539
Query: 1517 ---------LQATFRGLRKQVSARD-LFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRS 1566
L T R + VS R+ R L++ + K+V +++ K+
Sbjct: 540 KVKLEVQRQLIGTQREDQTAVSVRENASRGHLLTIPPAEAEGVPLVVDKDVFSVETPKKE 599
Query: 1567 ---LEGGNFIAGVLIQGTQERMSI----------PEALRRHILRPGTALVLLEAQAATGF 1613
L +F T E I P++ + + T + LE ++ T
Sbjct: 600 HQPLRNTSFTCQNEQAHTLETEYIHDETGGSHIKPQSKKLQVQVKKTLGIKLELKSETDG 659
Query: 1614 IIDPAENRKLTVEEAFKAGMFGKETY--VKLLSAERAVTGYTDPY-TGQQISLFQAMQKD 1670
+ P + +++ +++ F A KE+ + ++ TD +G++I L + +
Sbjct: 660 NVHPLDKKEM-LKKTFLAKDDHKESQEAQNIAGGSMMMSEKTDEEDSGREIFLSCSHPLE 718
Query: 1671 LIVREHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFD 1730
L+ E + +L AQ+ GGI ++ ++ A G L + + +GFFD
Sbjct: 719 LL-EEATLNVLSAQLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFD 777
Query: 1731 PNTHENLTYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKMRVGRFA 1790
T E+LT +++ + D K N + ++A VL RT + + A
Sbjct: 778 SQTCESLTTEEVINEGLMDE----------KLLHNVLMADKAISGVLDPRTQTLCSVKDA 827
Query: 1791 DQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAI 1850
V LL T +R+++ +GG+ L +G KV+
Sbjct: 828 VTV----GLLDKETATRILERQVV------TGGIIDL--------------KRGKKVSV- 862
Query: 1851 RGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTL--ECVKPYLEGSDCIAGVTVPSTR 1908
A+ L V DQ L L G A T+ + +E G+ P ++
Sbjct: 863 ---TLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQME----TTGLIDPDSK 915
Query: 1909 EVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERL 1968
+++ ++ + L+ A LL Q G ++ + +LSVD A GL+ E+L E+L
Sbjct: 916 APLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKL 975
Query: 1969 LKAERA-ATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPL 2027
+ E +P T + I L +A++ LI + EVQ TG +D RL L
Sbjct: 976 KRVENLNIHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQRLTL 1035
Query: 2028 ETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTG 2079
A + G L + A++S M VDP V Y EL ++C+ ++G
Sbjct: 1036 AEAKKEGLLTNE--AVLS--PGMMHGIVDPENCRIVPYSELVKKCKIDIESG 1083
Score = 116 bits (290), Expect = 7e-25
Identities = 101/409 (24%), Positives = 188/409 (45%), Gaps = 55/409 (13%)
Query: 632 KGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGY 691
KGLL T L+LLE+Q +I P+ + S+EE + +I P ++ +L + A+
Sbjct: 3 KGLLDQDTGLVLLESQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALALI 62
Query: 692 TDPYTGQ-QISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFD 750
+ + +S+ +A++K +I G+++LEA +ATGG + + ++ A+ +G
Sbjct: 63 SRLTESRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENCINLEEAFHQGLIS 122
Query: 751 QMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSPLVDSAT 810
L+ +L +K DPNT E + L L++RC+ E+G LLP+ +V
Sbjct: 123 AWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMV---- 178
Query: 811 QQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQVAKLLEA 870
S+K GR +VS + + R+VT+ +LLEA
Sbjct: 179 ---------SLKSGR----KVSIFRAVQEGLI-------------DRQVTV----RLLEA 208
Query: 871 ETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLG 930
+ I+ P R+TV + + +IDQ + +L +
Sbjct: 209 QL-FAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAILIRQLQ------------------ 249
Query: 931 AVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRR 990
GG+ +GQRL++ +A+ L+ ++AL +LE+ + ++ P S E L + +A+ +
Sbjct: 250 -TGGIIDTVTGQRLTIDEAVSNDLVAAKIALVILESLWSFMGLLWPESGEILPITDALEQ 308
Query: 991 GVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARL 1039
G+V EL ++ I P + + +S +A++ G++ + A L
Sbjct: 309 GIVSTELAHKILSNRQHIKALFLPATTEILSWKKAIESGILDRDLANNL 357
Score = 104 bits (260), Expect = 2e-21
Identities = 204/945 (21%), Positives = 369/945 (39%), Gaps = 123/945 (13%)
Query: 3701 RQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQH-AAGALGLPDLVAV 3759
+Q + L+DA + R P+SV + + +SE ++L H A G L
Sbjct: 50 QQLRELQDALALISRLTESRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENC 109
Query: 3760 LTRVIEETEERLSKVSFRGLRRQVSASELHTS-GILGPETLRDLAQGTKTLQEVTEMDSV 3818
+ EE + V S L TS ++ P T + + + +S
Sbjct: 110 IN-----LEEAFHQGLISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESG 164
Query: 3819 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 3878
+ L +AG +V K GR K+SI++A+ +G++ + LLEAQ G ++DP
Sbjct: 165 FKLLP-VKQLAGGMVSLKS--GR--KVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPR 219
Query: 3879 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 3938
RL+VEEAV ++ ++ +L + G D TGQ++++ +A+ DL+ + +
Sbjct: 220 TGHRLTVEEAVRHNLIDQDMACAILIRQLQTGGIIDTVTGQRLTIDEAVSNDLVAAKIAL 279
Query: 3939 RLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLT 3998
+LE+ + G++ P +P+ A +G E+ + K F P T E L+
Sbjct: 280 VILESLWSFMGLLWPESGEILPITDALEQGIVSTELAHKILSNRQHIKALFLPATTEILS 339
Query: 3999 YVQLLRRCVPDPDTGLYMLQLAGRGSAVH-QLSEELR-------CALRDARVTPGSGALQ 4050
+ + + + D D + + H QL++ L ++ P + A Q
Sbjct: 340 WKKAIESGILDRDLANNLKSICIPDVMPHMQLADSAEQNINPGAAVLPCSKSHPKATASQ 399
Query: 4051 GQSVSVWELLFYREVSEDRRQDLLSRYRASTLTVEELGATLTSLLAQAQAQARAEAEAGS 4110
+++ +++L+ + ++ Q LL L +EL TLTS R E +
Sbjct: 400 SENL-LFQLMTHSYINVQNGQRLL-------LLDKELMETLTS---------RDEYQTSP 442
Query: 4111 PRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLP--- 4167
P+ R T E G V + +SG+ R +F S + P
Sbjct: 443 PKVVEIGHQRQKTPE---GLQESANVKISGTFSSGWTVRLPE----FQFSSQNKEYPDRE 495
Query: 4168 -ALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEA 4226
T + E E++ P+ QD + +E P + + E Q + +
Sbjct: 496 DCTTEKGKKTTVETEDSSVENPE-QDLFVEQKERNPNIDALKVINKVKLEVQRQLIGTQR 554
Query: 4227 AAATAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALG 4286
TA + R E R + + + +G P+ V +FS + +++ ++ +
Sbjct: 555 EDQTAVSVR-ENASRGHLLTIPPAEAEGVPLVVDKDVFS--VETPKKEHQPLRNTSFTCQ 611
Query: 4287 LPDLVAVLTRVI-EETEERLSKVSFRGLRRQVSAS-------ELHTSGILGPETLRDLAQ 4338
+ T I +ET K + L+ QV + + T G + P +++ +
Sbjct: 612 NEQAHTLETEYIHDETGGSHIKPQSKKLQVQVKKTLGIKLELKSETDGNVHPLDKKEMLK 671
Query: 4339 GTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVL 4398
T ++ + + + G S + +D GR+ +S + L L +
Sbjct: 672 KTFLAKDDHKESQEAQNIAGGSMMMSEKTDEEDS-GREIFLSCSHPL---ELLEEATLNV 727
Query: 4399 LEAQAATGFVIDPVRNLRLSVEEAVAAGVV------------------------------ 4428
L AQ G + +L + EA++ G+V
Sbjct: 728 LSAQLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLTTE 787
Query: 4429 ----GGEIQEKL----LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIA 4480
G + EKL L A++A++G DP T S+ A+ L+ +E R+LE Q+
Sbjct: 788 EVINEGLMDEKLLHNVLMADKAISGVLDPRTQTLCSVKDAVTVGLLDKETATRILERQVV 847
Query: 4481 TGGVIDPVHSHRVPVDVAYRRGYFD-----EEMNRVLADPSDD---------------TK 4520
TGG+ID +V V +A G D E +N A D T
Sbjct: 848 TGGIIDLKRGKKVSVTLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQMETT 907
Query: 4521 GFFDPNTHENLTYVQLLRRCVPDPDTGLYML-QLAGRGSAVHQLS 4564
G DP++ LT VQ + R + + + + +L + G +H +S
Sbjct: 908 GLIDPDSKAPLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHIS 952
Score = 103 bits (258), Expect = 3e-21
Identities = 114/467 (24%), Positives = 200/467 (42%), Gaps = 54/467 (11%)
Query: 1575 GVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFKAGMF 1634
G+ + T +++ + EA+ R I+ TA+ L+E D LT EE G+
Sbjct: 736 GIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLTTEEVINEGLM 795
Query: 1635 GKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGIIDPV 1694
++ +L A++A++G DP T S+ A+ L+ +E R+LE Q+ TGGIID
Sbjct: 796 DEKLLHNVLMADKAISGVLDPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLK 855
Query: 1695 HSHRVPVDVAYRCGYFD-----EEMNRILADPSDD---------------TKGFFDPNTH 1734
+V V +A G D E +N A D T G DP++
Sbjct: 856 RGKKVSVTLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDSK 915
Query: 1735 ENLTYLQLLERCVEDPETGLYLL--QIIKKGENY------VYINEATRHVLQSRTAKMRV 1786
LT +Q ++R + + E + LL Q++ G + + ++ A RH L ++
Sbjct: 916 APLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKL 975
Query: 1787 GRFAD------------QVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTT 1834
R + + +S + T D KRE IQE A +G L+ T
Sbjct: 976 KRVENLNIHQIFNPETKENISLPKAIKLDLITSDLKRE-IQEVQAFTGNFVDLISGQRLT 1034
Query: 1835 IEETETQNQGIKVAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLE 1894
+ E + K + E + ++D + + + +E + YLE
Sbjct: 1035 LAEAK------KEGLLTNEAVLSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYLE 1088
Query: 1895 ---GSDCIAGVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSV 1951
SD GV + +V++L +A + + A +LEAQA TG ++D T ++L++
Sbjct: 1089 VIPFSDIKDGV----SDKVLTLSQAIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTL 1144
Query: 1952 DEAVDVGLVNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLI 1998
A++ LV+E + + + G D + + L +A++K+LI
Sbjct: 1145 ASALEEKLVDENMVRIIASHQVLNGGIVDIFSDQRVTLVEAIEKRLI 1191
Score = 103 bits (256), Expect = 6e-21
Identities = 204/947 (21%), Positives = 370/947 (39%), Gaps = 127/947 (13%)
Query: 2633 RQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQH-AAGALGLPDLVAV 2691
+Q + L+DA + R P+SV + + +SE ++L H A G L
Sbjct: 50 QQLRELQDALALISRLTESRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENC 109
Query: 2692 LTRVIEETEERLSKVSFRGLRRQVSASELHTS-GILGPETLRDLAQGTKTLQEVTEMDSV 2750
+ EE + V S L TS ++ P T + + + +S
Sbjct: 110 IN-----LEEAFHQGLISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESG 164
Query: 2751 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 2810
+ L +AG +V K GR K+SI++A+ +G++ + LLEAQ G ++DP
Sbjct: 165 FKLLP-VKQLAGGMVSLKS--GR--KVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPR 219
Query: 2811 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 2870
RL+VEEAV ++ ++ +L + G D TGQ++++ +A+ DL+ + +
Sbjct: 220 TGHRLTVEEAVRHNLIDQDMACAILIRQLQTGGIIDTVTGQRLTIDEAVSNDLVAAKIAL 279
Query: 2871 RLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLT 2930
+LE+ + G++ P +P+ A +G E+ + K F P T E L+
Sbjct: 280 VILESLWSFMGLLWPESGEILPITDALEQGIVSTELAHKILSNRQHIKALFLPATTEILS 339
Query: 2931 YVQLLRRCVPDPDTGLYMLQLAGRGSAVH-QLSEELR-------CALRDARVTPGSGALQ 2982
+ + + + D D + + H QL++ L ++ P + A Q
Sbjct: 340 WKKAIESGILDRDLANNLKSICIPDVMPHMQLADSAEQNINPGAAVLPCSKSHPKATASQ 399
Query: 2983 GQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGS 3042
+++ +++L+ + ++ Q LL L +EL TLTS + Q E G
Sbjct: 400 SENL-LFQLMTHSYINVQNGQRLL-------LLDKELMETLTS-RDEYQTSPPKVVEIGH 450
Query: 3043 PRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLP--- 3099
R E L+ + VK+ G W V + +F S + P
Sbjct: 451 QRQKTPEGLQESA-NVKIS---GTFSSGWTVRLPEF-----------QFSSQNKEYPDRE 495
Query: 3100 -ALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGE--GETQ 3156
T + E E++ P+ QD + +E P + + E Q + G +
Sbjct: 496 DCTTEKGKKTTVETEDSSVENPE-QDLFVEQKERNPNIDALKVINKVKLEVQRQLIGTQR 554
Query: 3157 EAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGA 3216
E A + +E R + + + +G P+ V +FS + +++ ++ +
Sbjct: 555 EDQTAVSV---RENASRGHLLTIPPAEAEGVPLVVDKDVFS--VETPKKEHQPLRNTSFT 609
Query: 3217 LGLPDLVAVLTRVI-EETEERLSKVSFRGLRRQVSAS-------ELHTSGILGPETLRDL 3268
+ T I +ET K + L+ QV + + T G + P +++
Sbjct: 610 CQNEQAHTLETEYIHDETGGSHIKPQSKKLQVQVKKTLGIKLELKSETDGNVHPLDKKEM 669
Query: 3269 AQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTAL 3328
+ T ++ + + + G S + +D GR+ +S + L L
Sbjct: 670 LKKTFLAKDDHKESQEAQNIAGGSMMMSEKTDEEDS-GREIFLSCSHPL---ELLEEATL 725
Query: 3329 VLLEAQAATGFVIDPVRNLRLSVEEAVAAGVV---------------------------- 3360
+L AQ G + +L + EA++ G+V
Sbjct: 726 NVLSAQLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLT 785
Query: 3361 ------GGEIQEKL----LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQ 3410
G + EKL L A++A++G DP T S+ A+ L+ +E R+LE Q
Sbjct: 786 TEEVINEGLMDEKLLHNVLMADKAISGVLDPRTQTLCSVKDAVTVGLLDKETATRILERQ 845
Query: 3411 IATGGVIDPVHSHRVPVDVAYRRGYFD-----EEMNRVLADPSDD--------------- 3450
+ TGG+ID +V V +A G D E +N A D
Sbjct: 846 VVTGGIIDLKRGKKVSVTLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQME 905
Query: 3451 TKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML-QLAGRGSAVHQLS 3496
T G DP++ LT VQ + R + + + + +L + G +H +S
Sbjct: 906 TTGLIDPDSKAPLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHIS 952
Score = 97.8 bits (242), Expect = 2e-19
Identities = 176/818 (21%), Positives = 323/818 (39%), Gaps = 119/818 (14%)
Query: 2226 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 2285
+AG +V K GR K+SI++A+ +G++ + LLEAQ G ++DP RL+VEE
Sbjct: 173 LAGGMVSLKS--GR--KVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEE 228
Query: 2286 PVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 2345
V ++ ++ +L + G D TGQ++++ +A+ DL+ + + +LE+ +
Sbjct: 229 AVRHNLIDQDMACAILIRQLQTGGIIDTVTGQRLTIDEAVSNDLVAAKIALVILESLWSF 288
Query: 2346 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCV 2405
G++ P +P+ A +G E+ + K F P T E L++ + + +
Sbjct: 289 MGLLWPESGEILPITDALEQGIVSTELAHKILSNRQHIKALFLPATTEILSWKKAIESGI 348
Query: 2406 PDPDTGLYMLQLAGRGSAVH-QLSEELR-------CALRDARVTPGSGALQGQSVSVWEL 2457
D D + + H QL++ L ++ P + A Q +++ +++L
Sbjct: 349 LDRDLANNLKSICIPDVMPHMQLADSAEQNINPGAAVLPCSKSHPKATASQSENL-LFQL 407
Query: 2458 LFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREAL 2517
+ + ++ Q LL L +EL TLTS R E + P+
Sbjct: 408 MTHSYINVQNGQRLL-------LLDKELMETLTS---------RDEYQTSPPKVVEIGHQ 451
Query: 2518 RAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLP----ALTRRLTA 2573
R T E G V + +SG+ R +F S + P T +
Sbjct: 452 RQKTPE---GLQESANVKISGTFSSGWTVRLPE----FQFSSQNKEYPDREDCTTEKGKK 504
Query: 2574 IIEEAEEAPGARPQLQD--ARRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAA 2631
E E++ P+ QD + R P + + + + Q G +E A +
Sbjct: 505 TTVETEDSSVENPE-QDLFVEQKERNPNIDALKVINKVKLEVQRQLIGTQREDQTAVSV- 562
Query: 2632 RRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAV 2691
+E R + + + +G P+ V +FS + +++ ++ + +
Sbjct: 563 --RENASRGHLLTIPPAEAEGVPLVVDKDVFS--VETPKKEHQPLRNTSFTCQNEQAHTL 618
Query: 2692 LTRVI-EETEERLSKVSFRGLRRQVSAS-------ELHTSGILGPETLRDLAQGTKTLQE 2743
T I +ET K + L+ QV + + T G + P +++ + T ++
Sbjct: 619 ETEYIHDETGGSHIKPQSKKLQVQVKKTLGIKLELKSETDGNVHPLDKKEMLKKTFLAKD 678
Query: 2744 VTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAAT 2803
+ + + G S + +D GR+ +S + L L +L AQ
Sbjct: 679 DHKESQEAQNIAGGSMMMSEKTDEEDS-GREIFLSCSHPL---ELLEEATLNVLSAQLLD 734
Query: 2804 GFVIDPVRNLRLSVEEAVAAGVV----------------------------------GGE 2829
G + +L + EA++ G+V G
Sbjct: 735 GGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLTTEEVINEGL 794
Query: 2830 IQEKL----LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDP 2885
+ EKL L A++A++G DP T S+ A+ L+ +E R+LE Q+ TGG+ID
Sbjct: 795 MDEKLLHNVLMADKAISGVLDPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDL 854
Query: 2886 VHSHRVPVDVAYRRGYFD-----EEMNRVLADPSDD---------------TKGFFDPNT 2925
+V V +A G D E +N A D T G DP++
Sbjct: 855 KRGKKVSVTLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDS 914
Query: 2926 HENLTYVQLLRRCVPDPDTGLYML-QLAGRGSAVHQLS 2962
LT VQ + R + + + + +L + G +H +S
Sbjct: 915 KAPLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHIS 952
Score = 97.8 bits (242), Expect = 2e-19
Identities = 106/467 (22%), Positives = 197/467 (42%), Gaps = 40/467 (8%)
Query: 614 GLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVI 673
G+ + ++L + EA +G++ TA+ L+E D + + + EE + ++
Sbjct: 736 GIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLTTEEVINEGLM 795
Query: 674 GPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPV 733
+ +L A++A++G DP T S+ A+ GL+ +E R+LE Q+ TGG+ID
Sbjct: 796 DEKLLHNVLMADKAISGVLDPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLK 855
Query: 734 HSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKG-FFDPNTHENLTYLQLLERCVRDPETG 792
+V V +A G D L++ +KG + E L LQ+ + DP++
Sbjct: 856 RGKKVSVTLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDSK 915
Query: 793 LYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLR 852
L + S L++ ++A + L V G + G R +
Sbjct: 916 APLTVVQSIDRGLLE--REEAVRLLTKQVVDG-------------GIIHHISGMRLSVDN 960
Query: 853 RYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTIS 912
+R + KL E I P + +++ + ++ +I L ++
Sbjct: 961 AFRHGLIGEDLAEKLKRVENLNIHQIFNPETKENISLPKAIKLDLITSDLKREI------ 1014
Query: 913 PEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGT 972
V+ + G L SGQRL+L +A ++ LL L +
Sbjct: 1015 -------QEVQAF------TGNFVDLISGQRLTLAEAKKEGLLTNEAVL----SPGMMHG 1057
Query: 973 IMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIP 1032
I+DP + + E V++ + E G+ + +D S K +++ QA++ G +
Sbjct: 1058 IVDPENCRIVPYSELVKKCKIDIE-SGQRYLEVIPFSDIKDGVSDKVLTLSQAIQLGKVD 1116
Query: 1033 WEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSS 1079
+ ++LEAQ TGGIID + L + A++ VD+ M ++S
Sbjct: 1117 FASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIAS 1163
Score = 97.8 bits (242), Expect = 2e-19
Identities = 118/507 (23%), Positives = 212/507 (41%), Gaps = 123/507 (24%)
Query: 1854 VTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSL 1913
+T ++ N ++D+K LH + L I+GV P T+ + S+
Sbjct: 784 LTTEEVINEGLMDEKLLHNV-------------------LMADKAISGVLDPRTQTLCSV 824
Query: 1914 HEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVN------------ 1961
+A L+ AT +LE Q TG ++D +K+SV A +GLV+
Sbjct: 825 KDAVTVGLLDKETATRILERQVVTGGIIDLKRGKKVSVTLASTLGLVDVADQPELINLEK 884
Query: 1962 --------EELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEVQVAT 2013
+ +RERL+ + TG DP + + + Q++ + L+E+ EA+RLL QV
Sbjct: 885 ASKGRDAEKTVRERLISLQMETTGLIDPDSKAPLTVVQSIDRGLLEREEAVRLLTKQVVD 944
Query: 2014 GGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMR-KRFVDPNTQEKVSYRELQERC 2072
GG+I RL ++ A+R G + +D+ + +++ + +P T+E +S +
Sbjct: 945 GGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRVENLNIHQIFNPETKENISLPK----- 999
Query: 2073 RPQEDTGWVLFPVNKAARDSEHIDDETRRALEAEQVEITVGRF----RGQKPTLWALLNS 2128
A + I + +R E ++V+ G F GQ+ TL
Sbjct: 1000 ----------------AIKLDLITSDLKR--EIQEVQAFTGNFVDLISGQRLTLAEAKKE 1041
Query: 2129 EYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLS 2188
+T E L M+ +++ + R + SEL+
Sbjct: 1042 GLLTNEAVLSPGMMH----------------GIVDPENC-----------RIVPYSELVK 1074
Query: 2189 SAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKD-QPGRQEK-MSIY 2246
I D+E+G +RYLE ++P D + G +K +++
Sbjct: 1075 KCKI------DIESG-------------QRYLE--------VIPFSDIKDGVSDKVLTLS 1107
Query: 2247 QAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERA 2306
QA+ G + + L +LEAQA TG +ID RL++ + +V + + S +
Sbjct: 1108 QAIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQVL 1167
Query: 2307 VTGYTDPYTGQQISLFQAMQKDLIVRE 2333
G D ++ Q+++L +A++K LI E
Sbjct: 1168 NGGIVDIFSDQRVTLVEAIEKRLISPE 1194
Score = 96.7 bits (239), Expect = 5e-19
Identities = 110/469 (23%), Positives = 192/469 (40%), Gaps = 76/469 (16%)
Query: 560 FSGLRDTVTPGELLKAEIIDQDLY-ERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLP 618
F G D+ T L E+I++ L E+L H L I+G+L P
Sbjct: 772 FQGFFDSQTCESLTTEEVINEGLMDEKLLHN---------------VLMADKAISGVLDP 816
Query: 619 GSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSV-------------- 664
+Q S+ +A GLL TA +LE Q TG IID K K SV
Sbjct: 817 RTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLKRGKKVSVTLASTLGLVDVADQ 876
Query: 665 ------EEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIR 718
E+A + V +L+S + TG DP + +++ Q++ +GL+ RE +R
Sbjct: 877 PELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDSKAPLTVVQSIDRGLLEREEAVR 936
Query: 719 LLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSD-DTKGFFDPNTHENLT 777
LL Q+ GG+I + R+ VD A+R G + L L + + F+P T EN++
Sbjct: 937 LLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRVENLNIHQIFNPETKENIS 996
Query: 778 YLQLLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELI 837
+ ++ + + + + + VD + Q L++ + +G L
Sbjct: 997 LPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQR-----LTLAEAKKEGL------LT 1045
Query: 838 NSEYFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQ---------ADIMLPALRSRVT 888
N S G ++ R V ++ K + + + +DI +T
Sbjct: 1046 NEAVLSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYLEVIPFSDIKDGVSDKVLT 1105
Query: 889 VHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQ 948
+ Q ++ G +D A T+ + L GG+ +G+RL+L
Sbjct: 1106 LSQAIQLGKVD-------FASTL------------KVLEAQANTGGIIDTATGKRLTLAS 1146
Query: 949 AMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPEL 997
A+ +KL+ + + Q G I+D S + +++ EA+ + ++ PEL
Sbjct: 1147 ALEEKLVDENMVRIIASHQVLNGGIVDIFSDQRVTLVEAIEKRLISPEL 1195
Score = 91.7 bits (226), Expect = 2e-17
Identities = 179/848 (21%), Positives = 334/848 (39%), Gaps = 68/848 (8%)
Query: 4235 RQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQH-AAGALGLPDLVAV 4293
+Q + L+DA + R P+SV + + +SE ++L H A G L
Sbjct: 50 QQLRELQDALALISRLTESRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENC 109
Query: 4294 LTRVIEETEERLSKVSFRGLRRQVSASELHTS-GILGPETLRDLAQGTKTLQEVTEMDSV 4352
+ EE + V S L TS ++ P T + + + +S
Sbjct: 110 IN-----LEEAFHQGLISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESG 164
Query: 4353 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 4412
+ L +AG +V K GR K+SI++A+ +G++ + LLEAQ G ++DP
Sbjct: 165 FKLLP-VKQLAGGMVSLKS--GR--KVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPR 219
Query: 4413 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 4472
RL+VEEAV ++ ++ +L + G D TGQ++++ +A+ DL+ + +
Sbjct: 220 TGHRLTVEEAVRHNLIDQDMACAILIRQLQTGGIIDTVTGQRLTIDEAVSNDLVAAKIAL 279
Query: 4473 RLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLT 4532
+LE+ + G++ P +P+ A +G E+ + K F P T E L+
Sbjct: 280 VILESLWSFMGLLWPESGEILPITDALEQGIVSTELAHKILSNRQHIKALFLPATTEILS 339
Query: 4533 YVQLLRRCVPDPDTGLYMLQLAGRGSAVH-QLSEELR-------CALRDARVTPGSGALQ 4584
+ + + + D D + + H QL++ L ++ P + A Q
Sbjct: 340 WKKAIESGILDRDLANNLKSICIPDVMPHMQLADSAEQNINPGAAVLPCSKSHPKATASQ 399
Query: 4585 GQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGS 4644
+++ +++L+ + ++ Q LL L +EL TLTS + Q E G
Sbjct: 400 SENL-LFQLMTHSYINVQNGQRLL-------LLDKELMETLTSR-DEYQTSPPKVVEIGH 450
Query: 4645 PRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLP--- 4701
R E L+ + VK+ G W V + +F S + P
Sbjct: 451 QRQKTPEGLQESA-NVKIS---GTFSSGWTVRLPEF-----------QFSSQNKEYPDRE 495
Query: 4702 -ALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGE--GETQ 4758
T + E E++ P+ QD + +E P + + E Q + G +
Sbjct: 496 DCTTEKGKKTTVETEDSSVENPE-QDLFVEQKERNPNIDALKVINKVKLEVQRQLIGTQR 554
Query: 4759 EAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGA 4818
E A + +E R + + + +G P+ V +FS + +++ ++ +
Sbjct: 555 EDQTAVSV---RENASRGHLLTIPPAEAEGVPLVVDKDVFS--VETPKKEHQPLRNTSFT 609
Query: 4819 LGLPDLVAVLTRVI-EETEERLSKVSFRGLRRQVSAS-------ELHTSGILGPETLRDL 4870
+ T I +ET K + L+ QV + + T G + P +++
Sbjct: 610 CQNEQAHTLETEYIHDETGGSHIKPQSKKLQVQVKKTLGIKLELKSETDGNVHPLDKKEM 669
Query: 4871 AQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTAL 4930
+ T ++ + + + G S + +D GR+ +S + L L
Sbjct: 670 LKKTFLAKDDHKESQEAQNIAGGSMMMSEKTDEEDS-GREIFLSCSHPL---ELLEEATL 725
Query: 4931 VLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQIS 4990
+L AQ G + +L + EA++ G+V KL+ G+ D T + ++
Sbjct: 726 NVLSAQLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLT 785
Query: 4991 LFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPS 5050
+ + + L+ + +L A A GV+DP V A G D+E + +
Sbjct: 786 TEEVINEGLMDEKLLHNVLMADKAISGVLDPRTQTLCSVKDAVTVGLLDKETATRILERQ 845
Query: 5051 DDTKGFFD 5058
T G D
Sbjct: 846 VVTGGIID 853
Score = 88.6 bits (218), Expect = 1e-16
Identities = 82/315 (26%), Positives = 137/315 (43%), Gaps = 41/315 (13%)
Query: 2124 ALLNSEYVTEEKKLQLVRMYRTHTRRALQTV------AQLILELIEKQETSNKHLWFQGI 2177
+++ SE EE + + + +H L+ AQL+ I ++T K L + I
Sbjct: 693 SMMMSEKTDEEDSGREIFLSCSHPLELLEEATLNVLSAQLLDGGIFHEQTGQKLLLNEAI 752
Query: 2178 RRQITASELLSSAIITEEMLQ---DLETGRSTTQE------LMEDDRVKRYLEGTSCIAG 2228
R I S + M Q D +T S T E LM++ + L I+G
Sbjct: 753 SRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLTTEEVINEGLMDEKLLHNVLMADKAISG 812
Query: 2229 VLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVP 2288
VL P Q S+ A+ G+L TA +LE Q TG +ID R ++SV
Sbjct: 813 VL-----DPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLKRGKKVSVTLAST 867
Query: 2289 AGVVG--------------------SEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKD 2328
G+V ++E+L+S + TG DP + +++ Q++ +
Sbjct: 868 LGLVDVADQPELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDSKAPLTVVQSIDRG 927
Query: 2329 LIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSD-DTKGFF 2387
L+ RE +RLL Q+ GG+I + R+ VD A+R G E++ L + + F
Sbjct: 928 LLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRVENLNIHQIF 987
Query: 2388 DPNTHENLTYVQLLR 2402
+P T EN++ + ++
Sbjct: 988 NPETKENISLPKAIK 1002
Score = 88.6 bits (218), Expect = 1e-16
Identities = 116/546 (21%), Positives = 229/546 (41%), Gaps = 64/546 (11%)
Query: 1901 GVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLV 1960
G+ T + + L+EA + ++P+ A L+E D T + L+ +E ++ GL+
Sbjct: 736 GIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLTTEEVINEGLM 795
Query: 1961 NEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQ 2020
+E+L +L A++A +G DP T + A+ L++K A R+LE QV TGG+ID +
Sbjct: 796 DEKLLHNVLMADKAISGVLDPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLK 855
Query: 2021 HHHRLPLETAYRRGCLH-KDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTG 2079
++ + A G + D LI+ +K + R + +E++ ++ E TG
Sbjct: 856 RGKKVSVTLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQM-------ETTG 908
Query: 2080 WVLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQL 2139
++ P +KA D R LE E+ L ++ V + +
Sbjct: 909 -LIDPDSKAPLTVVQSID--RGLLEREEA---------------VRLLTKQVVDGGIIHH 950
Query: 2140 VRMYRTHTRRALQ--TVAQLILELIEKQETSNKHLWFQG-IRRQITASELLSSAIITEEM 2196
+ R A + + + + E +++ E N H F + I+ + + +IT ++
Sbjct: 951 ISGMRLSVDNAFRHGLIGEDLAEKLKRVENLNIHQIFNPETKENISLPKAIKLDLITSDL 1010
Query: 2197 LQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRP 2256
++++ ++ T ++ +R L AK + + + M G++ P
Sbjct: 1011 KREIQEVQAFTGNFVDLISGQRL---------TLAEAKKEGLLTNEAVLSPGMMHGIVDP 1061
Query: 2257 GTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTG 2316
++ ++ ID R E +P + + +K+L+
Sbjct: 1062 ENCRIVPYSELVKKCKIDIESGQRYL--EVIPFSDIKDGVSDKVLT-------------- 1105
Query: 2317 QQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVL 2376
L QA+Q + +++LEAQ TGG+ID R+ + A DE M R++
Sbjct: 1106 ----LSQAIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRII 1161
Query: 2377 ADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELR---- 2432
A G D + + +T V+ + + + P+ M+Q+ + H+ E +
Sbjct: 1162 ASHQVLNGGIVDIFSDQRVTLVEAIEKRLISPELA-NMIQIDSSEFSDHRAQIEKQEGIE 1220
Query: 2433 -CALRD 2437
CAL++
Sbjct: 1221 VCALQN 1226
Score = 87.0 bits (214), Expect = 4e-16
Identities = 107/428 (25%), Positives = 178/428 (41%), Gaps = 46/428 (10%)
Query: 45 GVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGLV 104
G++ E +GQ + A+ +G++P+ L+E G D + L + + +GL+
Sbjct: 736 GIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLTTEEVINEGLM 795
Query: 105 GLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPA 164
+L +L A++A +G DP ++ A+ ++D+ LE Q+ TGG++D
Sbjct: 796 DEKLLHNVLMADKAISGVLDPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLK 855
Query: 165 QGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCVRAPGS 224
+G V+ A GL+D +L LE + R ERL Q+ + P S
Sbjct: 856 RGKKVSVTLASTLGLVDVADQPELINLEKASKG-RDAEKTVRERLISLQMETTGLIDPDS 914
Query: 225 GLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSAR--------AE 276
L ++ R + A LL ++D + + RL +VD + R AE
Sbjct: 915 KAPLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRL-SVDNAFRHGLIGEDLAE 973
Query: 277 VRRYLEGTGSVAGVVLLPEGHKK-SFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQ 335
+ +E + PE + S +A L+ + E QA T VD I+GQ
Sbjct: 974 KLKRVENLN--IHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQ 1031
Query: 336 RLWVDEAVRAGL------VSPELHEQLLVAEQA--------------------------- 362
RL + EA + GL +SP + ++ E
Sbjct: 1032 RLTLAEAKKEGLLTNEAVLSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYLEVIP 1091
Query: 363 VTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCG 422
+ D S + L QA++ G VD L++L+AQ TGG++ A RL L +AL
Sbjct: 1092 FSDIKDGVSDKVLTLSQAIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEK 1151
Query: 423 CLDEDTQR 430
+DE+ R
Sbjct: 1152 LVDENMVR 1159
Score = 85.1 bits (209), Expect = 2e-15
Identities = 81/405 (20%), Positives = 177/405 (43%), Gaps = 67/405 (16%)
Query: 1930 LLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERA-ATGYRDPATGDTIP 1988
LLE+Q L+ P T + LS++E + L+N ++ ++L + + A A R + +
Sbjct: 14 LLESQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALALISRLTESRGPLS 73
Query: 1989 LFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQK 2048
+ +A++K++I + L++LE +ATGG + + LE A+ +G + +++++
Sbjct: 74 VVEAIEKRIISETVGLKILEAHLATGGFSLSPSENCINLEEAFHQGLISAWLHSVLESYL 133
Query: 2049 HMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALEAEQV 2108
K +DPNT EK+ +L +RC +++G+ L PV + A
Sbjct: 134 RTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGG----------------- 176
Query: 2109 EITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETS 2168
V G+K +++ + + + ++L+ AQL I T
Sbjct: 177 --MVSLKSGRKVSIFRAVQEGLIDRQVTVRLLE-------------AQLFAGGIVDPRTG 221
Query: 2169 NKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAG 2228
++ + +R + ++ + +I + L+TG G
Sbjct: 222 HRLTVEEAVRHNLIDQDMACAILI-----RQLQTG------------------------G 252
Query: 2229 VLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVP 2288
++ Q +++I +A+ ++ ALV+LE+ + ++ P L + + +
Sbjct: 253 IIDTVTGQ-----RLTIDEAVSNDLVAAKIALVILESLWSFMGLLWPESGEILPITDALE 307
Query: 2289 AGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVRE 2333
G+V +E+ K+LS + + P T + +S +A++ ++ R+
Sbjct: 308 QGIVSTELAHKILSNRQHIKALFLPATTEILSWKKAIESGILDRD 352
Score = 85.1 bits (209), Expect = 2e-15
Identities = 102/467 (21%), Positives = 191/467 (40%), Gaps = 55/467 (11%)
Query: 1200 RGEVP---AVWLLDA-----GIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGV 1251
RG VP AV L++ G +T E+L + ++ + L ++GV
Sbjct: 754 RGIVPSHTAVKLMEKLNMFQGFFDSQTCESLTTEEVINEGLMDEKLLHNVLMADKAISGV 813
Query: 1252 LLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLV-- 1309
L + S+ AV GLL R+LE QV +G ++D +++SV A +GLV
Sbjct: 814 LDPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLKRGKKVSVTLASTLGLVDV 873
Query: 1310 --------------GRE----LSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNE 1351
GR+ + E+L + G DP S+A L++ Q++++GL+ + E
Sbjct: 874 ADQPELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDSKAPLTVVQSIDRGLLEREE 933
Query: 1352 GLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDN-KFFFDPSARD 1410
+ LL Q+ GG++ + G+ L A R GL+ ++ L V+ N F+P ++
Sbjct: 934 AVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRVENLNIHQIFNPETKE 993
Query: 1411 QVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLW 1470
++ + + L + SD E+ + A + + +S R
Sbjct: 994 NISLPK-----------AIKLDLITSDLKREIQEVQAFTGNFVDL-ISGQRLTLAEAKKE 1041
Query: 1471 DLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVTALVEAAERQPLQATFRGLRKQVSA 1530
LL +E V + + + R ++V +E+ +R F ++ VS
Sbjct: 1042 GLLTNEAVLSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYLEVIPFSDIKDGVSD 1101
Query: 1531 RDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEA 1590
+ L +Q I +D S + LE G++ T +R+++ A
Sbjct: 1102 KVLTLSQAIQLGKVD--------------FASTLKVLEAQANTGGIIDTATGKRLTLASA 1147
Query: 1591 LRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFKAGMFGKE 1637
L ++ ++ Q G I+D ++++T+ EA + + E
Sbjct: 1148 LEEKLVDENMVRIIASHQVLNGGIVDIFSDQRVTLVEAIEKRLISPE 1194
Score = 84.3 bits (207), Expect = 3e-15
Identities = 94/398 (23%), Positives = 170/398 (42%), Gaps = 56/398 (14%)
Query: 41 RSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQ 100
++I+GV + SV A+ GLL +LE Q TGG++DL RG+ + V+ A
Sbjct: 808 KAISGVLDPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLKRGKKVSVTLAST 867
Query: 101 QGLVGL--------------------ELKEKLLAAERATTGYPDPYGGEKLALFQAIGKE 140
GLV + ++E+L++ + TTG DP L + Q+I +
Sbjct: 868 LGLVDVADQPELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDSKAPLTVVQSIDRG 927
Query: 141 VVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRF 200
+++R L Q+ GG++ G+ ++ + A GL+ + KL +E +
Sbjct: 928 LLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRVE-NLNIHQI 986
Query: 201 LNPNTLERLTYHQ-----LLERCVRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDE 255
NP T E ++ + L+ ++ + G ++ AE + G+L
Sbjct: 987 FNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQRLTLAEAKKEGLLTN 1046
Query: 256 QAV--QGLREG----------------RLAAVDVSA---RAEVRRYLEGTGSVAGVVLLP 294
+AV G+ G + +D+ + EV + + V+ VL
Sbjct: 1047 EAVLSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYLEVIPFSDIKDGVSDKVL-- 1104
Query: 295 EGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELHE 354
+ QA + + L +LEAQA T ++D TG+RL + A+ LV +
Sbjct: 1105 -----TLSQAIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENM-V 1158
Query: 355 QLLVAEQAVTGH-HDPFSGSQIPLFQAMKKGLVDRPLA 391
+++ + Q + G D FS ++ L +A++K L+ LA
Sbjct: 1159 RIIASHQVLNGGIVDIFSDQRVTLVEAIEKRLISPELA 1196
Score = 83.2 bits (204), Expect = 6e-15
Identities = 84/400 (21%), Positives = 175/400 (43%), Gaps = 24/400 (6%)
Query: 745 RRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSP 804
++G DQ L+LL+ G P T ENL+ + + R + +P+ L L +
Sbjct: 2 QKGLLDQDTGLVLLESQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALA- 60
Query: 805 LVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQRE-VTLGQ 863
L+ T+ +S E I SE ++L + +L
Sbjct: 61 LISRLTESRGP---------------LSVVEAIEKRIISETVGLKILEAHLATGGFSLSP 105
Query: 864 VAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVR 923
+ E ++ L S + + +ID +++ + ++ +
Sbjct: 106 SENCINLEEAFHQGLISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGF 165
Query: 924 RYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLS 983
+ L GG+ L SG+++S+++A+++ L+ +V + LLEAQ G I+DP + L+
Sbjct: 166 KLLPVKQLAGGMVSLKSGRKVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLT 225
Query: 984 VDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQ 1043
V+EAVR ++ ++ + + G D +G+++++ +A+ L+ + A +LE+
Sbjct: 226 VEEAVRHNLIDQDMACAILIRQLQTGGIIDTVTGQRLTIDEAVSNDLVAAKIALVILESL 285
Query: 1044 VATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSETFPT---PDGQGRTSYAQLLE 1100
+ G++ P S LP+ A+++G V E+ + S+ + P S+ + +E
Sbjct: 286 WSFMGLLWPESGEILPITDALEQGIVSTELAHKILSNRQHIKALFLPATTEILSWKKAIE 345
Query: 1101 E--CPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGA 1138
RD + L + +P+ P + + ++++ PGA
Sbjct: 346 SGILDRDLANNLKSICIPDVMPHMQLADSAEQNIN--PGA 383
Score = 82.8 bits (203), Expect = 8e-15
Identities = 129/542 (23%), Positives = 220/542 (40%), Gaps = 89/542 (16%)
Query: 198 LRFLNPNTLERLTYHQLLERCVRAPGSGLALLPLKITFRSMGGAVSAAELLEV-----GI 252
L L TL L+ QLL+ + +G LL + R + + +A +L+E G
Sbjct: 717 LELLEEATLNVLSA-QLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGF 775
Query: 253 LDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPM 312
D Q + L + + + L +++GV+ S A T LL
Sbjct: 776 FDSQTCESLTTEEVINEGLMDEKLLHNVLMADKAISGVLDPRTQTLCSVKDAVTVGLLDK 835
Query: 313 GTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVS----PEL---------------- 352
TA +LE Q T ++D G+++ V A GLV PEL
Sbjct: 836 ETATRILERQVVTGGIIDLKRGKKVSVTLASTLGLVDVADQPELINLEKASKGRDAEKTV 895
Query: 353 HEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLR 412
E+L+ + TG DP S + + + Q++ +GL++R A+RLL Q+ GG++ +R
Sbjct: 896 RERLISLQMETTGLIDPDSKAPLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMR 955
Query: 413 LPLEAALRCGCLDEDTQRQLSQAGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGP 472
L ++ A R G + ED +L R E L + +PET
Sbjct: 956 LSVDNAFRHGLIGEDLAEKLK-------------RVENLNIHQIFNPETK---------- 992
Query: 473 RGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQ 532
S +A+ T + K + V + F + IS QR LA+ +
Sbjct: 993 ----------ENISLPKAIKLDLITSDL-KREIQEVQAFTGNFVDLISG-QRLTLAEAKK 1040
Query: 533 EGTLSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQAT 592
EG L+ E + ++PG + I+D + + + +
Sbjct: 1041 EGLLTNEAV-------------------------LSPG--MMHGIVDPENCRIVPYSELV 1073
Query: 593 AKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGF 652
K + S QRYL+ + + S + L++ +A G + + L +LEAQA TG
Sbjct: 1074 KKCKIDIESGQRYLEVIP-FSDIKDGVSDKVLTLSQAIQLGKVDFASTLKVLEAQANTGG 1132
Query: 653 IIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIV 712
IID K ++ AL ++ ++ + S + G D ++ Q+++L +A++K LI
Sbjct: 1133 IIDTATGKRLTLASALEEKLVDENMVRIIASHQVLNGGIVDIFSDQRVTLVEAIEKRLIS 1192
Query: 713 RE 714
E
Sbjct: 1193 PE 1194
Score = 82.0 bits (201), Expect = 1e-14
Identities = 99/395 (25%), Positives = 159/395 (40%), Gaps = 36/395 (9%)
Query: 74 LLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLAL 133
+L AQ GG+ GQ L +++A+ +G+V KL+ G+ D E L
Sbjct: 727 VLSAQLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLTT 786
Query: 134 FQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLLDRETWHKLSELEP 193
+ I + ++D L + L A G++DP L + + A GLLD+ET ++ E +
Sbjct: 787 EEVINEGLMDEKLLHNVLMADKAISGVLDPRTQTLCSVKDAVTVGLLDKETATRILERQV 846
Query: 194 GTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALLPLKITFRSMGGAVSAAELLEVGIL 253
TG + L + +T S G V A+ E+ L
Sbjct: 847 VTGGIIDLKRGK------------------------KVSVTLASTLGLVDVADQPELINL 882
Query: 254 DEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMG 313
++ + +GR A V R + +E TG + P + Q+ LL
Sbjct: 883 EKAS-----KGRDAEKTVRERL-ISLQMETTGLIDPDSKAP----LTVVQSIDRGLLERE 932
Query: 314 TALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELHEQLLVAEQA-VTGHHDPFSG 372
A+ LL Q ++ I+G RL VD A R GL+ +L E+L E + +P +
Sbjct: 933 EAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRVENLNIHQIFNPETK 992
Query: 373 SQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQL 432
I L +A+K L+ L + + Q TG V RL L A + G L +
Sbjct: 993 ENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQRLTLAEAKKEGLLTNEAVLSP 1052
Query: 433 SQAGSFSDGTHGGL-RYEQLLALCVTDPETGLAFL 466
D + + Y +L+ C D E+G +L
Sbjct: 1053 GMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYL 1087
Score = 80.1 bits (196), Expect = 5e-14
Identities = 52/177 (29%), Positives = 95/177 (53%), Gaps = 8/177 (4%)
Query: 2783 MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERA-- 2840
M KG+L T LVLLE+Q +I P LS+EE +A ++ ++ ++L + A
Sbjct: 1 MQKGLLDQDTGLVLLESQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALA 60
Query: 2841 -VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRR 2899
++ T+ + +S+ +A++K +I G+++LEA +ATGG + + ++ A+ +
Sbjct: 61 LISRLTE--SRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENCINLEEAFHQ 118
Query: 2900 GYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML---QLAG 2953
G ++ VL +K DPNT E + + L++RC+ ++G +L QLAG
Sbjct: 119 GLISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAG 175
Score = 80.1 bits (196), Expect = 5e-14
Identities = 52/177 (29%), Positives = 95/177 (53%), Gaps = 8/177 (4%)
Query: 3317 MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERA-- 3374
M KG+L T LVLLE+Q +I P LS+EE +A ++ ++ ++L + A
Sbjct: 1 MQKGLLDQDTGLVLLESQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALA 60
Query: 3375 -VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRR 3433
++ T+ + +S+ +A++K +I G+++LEA +ATGG + + ++ A+ +
Sbjct: 61 LISRLTE--SRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENCINLEEAFHQ 118
Query: 3434 GYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML---QLAG 3487
G ++ VL +K DPNT E + + L++RC+ ++G +L QLAG
Sbjct: 119 GLISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAG 175
Score = 80.1 bits (196), Expect = 5e-14
Identities = 52/177 (29%), Positives = 95/177 (53%), Gaps = 8/177 (4%)
Query: 3851 MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERA-- 3908
M KG+L T LVLLE+Q +I P LS+EE +A ++ ++ ++L + A
Sbjct: 1 MQKGLLDQDTGLVLLESQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALA 60
Query: 3909 -VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRR 3967
++ T+ + +S+ +A++K +I G+++LEA +ATGG + + ++ A+ +
Sbjct: 61 LISRLTE--SRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENCINLEEAFHQ 118
Query: 3968 GYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML---QLAG 4021
G ++ VL +K DPNT E + + L++RC+ ++G +L QLAG
Sbjct: 119 GLISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAG 175
Score = 80.1 bits (196), Expect = 5e-14
Identities = 52/177 (29%), Positives = 95/177 (53%), Gaps = 8/177 (4%)
Query: 4385 MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERA-- 4442
M KG+L T LVLLE+Q +I P LS+EE +A ++ ++ ++L + A
Sbjct: 1 MQKGLLDQDTGLVLLESQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALA 60
Query: 4443 -VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRR 4501
++ T+ + +S+ +A++K +I G+++LEA +ATGG + + ++ A+ +
Sbjct: 61 LISRLTE--SRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENCINLEEAFHQ 118
Query: 4502 GYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML---QLAG 4555
G ++ VL +K DPNT E + + L++RC+ ++G +L QLAG
Sbjct: 119 GLISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAG 175
Score = 80.1 bits (196), Expect = 5e-14
Identities = 52/188 (27%), Positives = 93/188 (49%)
Query: 590 QATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAA 649
+A K + S + L+ G L S+ +++ EA +GL+ +L
Sbjct: 76 EAIEKRIISETVGLKILEAHLATGGFSLSPSENCINLEEAFHQGLISAWLHSVLESYLRT 135
Query: 650 TGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKG 709
+ +IDP + + + ++ ++ + KLL ++ G +G+++S+F+A+Q+G
Sbjct: 136 SKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMVSLKSGRKVSIFRAVQEG 195
Query: 710 LIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFD 769
LI R+ +RLLEAQ+ GG++DP HR+ V+ A R DQ + +L T G D
Sbjct: 196 LIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAILIRQLQTGGIID 255
Query: 770 PNTHENLT 777
T + LT
Sbjct: 256 TVTGQRLT 263
Score = 80.1 bits (196), Expect = 5e-14
Identities = 82/312 (26%), Positives = 132/312 (42%), Gaps = 22/312 (7%)
Query: 56 SVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAA 115
+V ++++GLL LL Q GG++ G L V A + GL+G +L EKL
Sbjct: 919 TVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRV 978
Query: 116 ERATTGYP-DPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPA 174
E +P E ++L +AI +++ L + EVQ TG VD G + A
Sbjct: 979 ENLNIHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQRLTLAEA 1038
Query: 175 CHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALLPLKIT 234
+GLL E + L PG ++P + Y +L+++C SG L + I
Sbjct: 1039 KKEGLLTNE-----AVLSPGMMH-GIVDPENCRIVPYSELVKKCKIDIESGQRYLEV-IP 1091
Query: 235 FRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLLP 294
F + VS L QA+Q L VD ++ +V LE + G++
Sbjct: 1092 FSDIKDGVSDKVLTL-----SQAIQ------LGKVDFASTLKV---LEAQANTGGIIDTA 1137
Query: 295 EGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELHE 354
G + + A E L+ + Q +VD + QR+ + EA+ L+SPEL
Sbjct: 1138 TGKRLTLASALEEKLVDENMVRIIASHQVLNGGIVDIFSDQRVTLVEAIEKRLISPELAN 1197
Query: 355 QLLVAEQAVTGH 366
+ + + H
Sbjct: 1198 MIQIDSSEFSDH 1209
Score = 79.7 bits (195), Expect = 7e-14
Identities = 101/435 (23%), Positives = 173/435 (39%), Gaps = 62/435 (14%)
Query: 381 MKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLSQAGSFSD 440
M+KGL+D+ L LL++Q+ GL+ P L LE + ++ +QL +
Sbjct: 1 MQKGLLDQDTGLVLLESQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLREL----- 55
Query: 441 GTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTATATVSV 500
+ LAL ++ L S GP I S L A ++
Sbjct: 56 --------QDALAL--------ISRLTESRGPLSVVEAIEKRI-ISETVGLKILEAHLAT 98
Query: 501 GKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAELSATLEQAAATARVTF 560
G F P SE L + + +G +S A L + LE T++
Sbjct: 99 GGFSLSP-------------SENCINLEEAFHQGLIS-----AWLHSVLESYLRTSK--- 137
Query: 561 SGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGS 620
+ID + E++ + + S + L G++ S
Sbjct: 138 ---------------NLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMVSLKS 182
Query: 621 QERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAK 680
++SI+ A +GL+ + LLEAQ G I+DP+ +VEEA+R +I D+
Sbjct: 183 GRKVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACA 242
Query: 681 LLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPV 740
+L + G D TGQ++++ +A+ L+ + + +LE+ + G++ P +P+
Sbjct: 243 ILIRQLQTGGIIDTVTGQRLTIDEAVSNDLVAAKIALVILESLWSFMGLLWPESGEILPI 302
Query: 741 DVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYL----L 796
A +G L +L K F P T E L++ + +E + D + L +
Sbjct: 303 TDALEQGIVSTELAHKILSNRQHIKALFLPATTEILSWKKAIESGILDRDLANNLKSICI 362
Query: 797 PLSSTQSPLVDSATQ 811
P L DSA Q
Sbjct: 363 PDVMPHMQLADSAEQ 377
Score = 79.7 bits (195), Expect = 7e-14
Identities = 77/311 (24%), Positives = 139/311 (44%), Gaps = 12/311 (3%)
Query: 4769 RQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQH-AAGALGLPDLVAV 4827
+Q + L+DA + R P+SV + + +SE ++L H A G L
Sbjct: 50 QQLRELQDALALISRLTESRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENC 109
Query: 4828 LTRVIEETEERLSKVSFRGLRRQVSASELHTS-GILGPETLRDLAQGTKTLQEVTEMDSV 4886
+ EE + V S L TS ++ P T + + + +S
Sbjct: 110 IN-----LEEAFHQGLISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESG 164
Query: 4887 KRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPV 4946
+ L +AG +V K GR K+SI++A+ +G++ + LLEAQ G ++DP
Sbjct: 165 FKLLP-VKQLAGGMVSLKS--GR--KVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPR 219
Query: 4947 RNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGI 5006
RL+VEEAV ++ ++ +L + G D TGQ++++ +A+ DL+ + +
Sbjct: 220 TGHRLTVEEAVRHNLIDQDMACAILIRQLQTGGIIDTVTGQRLTIDEAVSNDLVAAKIAL 279
Query: 5007 RLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLT 5066
+LE+ + G++ P +P+ A +G E+ + K F P T E L+
Sbjct: 280 VILESLWSFMGLLWPESGEILPITDALEQGIVSTELAHKILSNRQHIKALFLPATTEILS 339
Query: 5067 YLQLLQRATLD 5077
+ + ++ LD
Sbjct: 340 WKKAIESGILD 350
Score = 79.0 bits (193), Expect = 1e-13
Identities = 90/359 (25%), Positives = 154/359 (42%), Gaps = 19/359 (5%)
Query: 562 GLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVG---SLASAQRYLQGTGCIAGLLLP 618
GL D T LL++++I L E G+ + + G +L + Q Y Q L L
Sbjct: 4 GLLDQDTGLVLLESQVIMSGLIAP-ETGENLSLEEGIARNLINPQMYQQLRELQDALALI 62
Query: 619 G----SQERLSIYEARCKGLLRPGTALILLEAQAAT-GFIIDPKANKGHSVEEALRAAVI 673
S+ LS+ EA K ++ L +LEA AT GF + P N ++EEA +I
Sbjct: 63 SRLTESRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSEN-CINLEEAFHQGLI 121
Query: 674 GPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPV 733
+ + L S R DP T ++I L MQ+ ++ +E G +LL + GG++
Sbjct: 122 SAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMVSLK 181
Query: 734 HSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGL 793
+V + A + G D+ + + LL+ G DP T LT + + + D +
Sbjct: 182 SGRKVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMAC 241
Query: 794 YLLPLSSTQSPLVDSATQQ------AFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRR 847
+L ++D+ T Q A N L++ K + S W + + G
Sbjct: 242 AILIRQLQTGGIIDTVTGQRLTIDEAVSNDLVAAKIALVILE--SLWSFMGLLWPESGEI 299
Query: 848 RQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQV 906
+ Q V+ K+L + Q + LPA ++ + +E+GI+D+ L + +
Sbjct: 300 LPITDALEQGIVSTELAHKIL-SNRQHIKALFLPATTEILSWKKAIESGILDRDLANNL 357
Score = 79.0 bits (193), Expect = 1e-13
Identities = 122/550 (22%), Positives = 219/550 (39%), Gaps = 65/550 (11%)
Query: 711 IVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDP 770
++ E + +L AQ+ GG+ ++ ++ A RG + L++ + +GFFD
Sbjct: 719 LLEEATLNVLSAQLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDS 778
Query: 771 NTHENLTYLQLLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQR 830
T E+LT +++ + D + +L S ++D TQ L SVK G
Sbjct: 779 QTCESLTTEEVINEGLMDEKLLHNVLMADKAISGVLDPRTQ-----TLCSVKDAVTVG-- 831
Query: 831 VSAWELINSEYFSEGRRRQL-------LRRYRQREVTLGQVAKLLEAETQRQADIMLPAL 883
L++ E + RQ+ L+R ++ VTL L++ Q + + A
Sbjct: 832 -----LLDKETATRILERQVVTGGIIDLKRGKKVSVTLASTLGLVDVADQPELINLEKAS 886
Query: 884 RSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQR 943
+ R + E I L G I P+ S
Sbjct: 887 KGRDAEKTVRERLI----SLQMETTGLIDPD-------------------------SKAP 917
Query: 944 LSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKR 1003
L++ Q++ + LL A+ LL Q G I+ S LSVD A R G++G +L +LKR
Sbjct: 918 LTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKR 977
Query: 1004 AEGA-IAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPV 1062
E I +P + + +S+ +A+K LI + + E Q TG +D S L +
Sbjct: 978 VENLNIHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQRLTLAE 1037
Query: 1063 AIQRGYVDQEMETALSSSSETFPTPDGQGRTSYAQLLEECPRDETSGLHLLP-LPESAPA 1121
A + G + E + P+ Y++L+++C D SG L +P S
Sbjct: 1038 AKKEGLLTNEAVLS-PGMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYLEVIPFSDIK 1096
Query: 1122 LPTEEQVQRSLQAVP-GAKDGTSLWDLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQ 1180
++V QA+ G D S +L + + G+++ R T+ L
Sbjct: 1097 DGVSDKVLTLSQAIQLGKVDFASTLKVLEA----QANTGGIIDTATGKRLTLASALEEKL 1152
Query: 1181 RWVQETKLLAQARVMVPG-----PRGEVPAVWLLDAGIITQETLEAL----AQGTQSPAQ 1231
+++A +V+ G V V ++ +I+ E + ++ + AQ
Sbjct: 1153 VDENMVRIIASHQVLNGGIVDIFSDQRVTLVEAIEKRLISPELANMIQIDSSEFSDHRAQ 1212
Query: 1232 VAEQPAVKAC 1241
+ +Q ++ C
Sbjct: 1213 IEKQEGIEVC 1222
Score = 79.0 bits (193), Expect = 1e-13
Identities = 57/204 (27%), Positives = 95/204 (46%), Gaps = 26/204 (12%)
Query: 2754 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 2813
L I+GVL P Q S+ A+ G+L TA +LE Q TG +ID R
Sbjct: 804 LMADKAISGVL-----DPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLKRGK 858
Query: 2814 RLSVEEAVAAGVVG--------------------GEIQEKLLSAERAVTGYTDPYTGQQI 2853
++SV A G+V ++E+L+S + TG DP + +
Sbjct: 859 KVSVTLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDSKAPL 918
Query: 2854 SLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADP 2913
++ Q++ + L+ RE +RLL Q+ GG+I + R+ VD A+R G E++ L
Sbjct: 919 TVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRV 978
Query: 2914 SD-DTKGFFDPNTHENLTYVQLLR 2936
+ + F+P T EN++ + ++
Sbjct: 979 ENLNIHQIFNPETKENISLPKAIK 1002
Score = 79.0 bits (193), Expect = 1e-13
Identities = 57/204 (27%), Positives = 95/204 (46%), Gaps = 26/204 (12%)
Query: 3288 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 3347
L I+GVL P Q S+ A+ G+L TA +LE Q TG +ID R
Sbjct: 804 LMADKAISGVL-----DPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLKRGK 858
Query: 3348 RLSVEEAVAAGVVG--------------------GEIQEKLLSAERAVTGYTDPYTGQQI 3387
++SV A G+V ++E+L+S + TG DP + +
Sbjct: 859 KVSVTLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDSKAPL 918
Query: 3388 SLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADP 3447
++ Q++ + L+ RE +RLL Q+ GG+I + R+ VD A+R G E++ L
Sbjct: 919 TVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRV 978
Query: 3448 SD-DTKGFFDPNTHENLTYVQLLR 3470
+ + F+P T EN++ + ++
Sbjct: 979 ENLNIHQIFNPETKENISLPKAIK 1002
Score = 79.0 bits (193), Expect = 1e-13
Identities = 57/204 (27%), Positives = 95/204 (46%), Gaps = 26/204 (12%)
Query: 3822 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 3881
L I+GVL P Q S+ A+ G+L TA +LE Q TG +ID R
Sbjct: 804 LMADKAISGVL-----DPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLKRGK 858
Query: 3882 RLSVEEAVAAGVVG--------------------GEIQEKLLSAERAVTGYTDPYTGQQI 3921
++SV A G+V ++E+L+S + TG DP + +
Sbjct: 859 KVSVTLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDSKAPL 918
Query: 3922 SLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADP 3981
++ Q++ + L+ RE +RLL Q+ GG+I + R+ VD A+R G E++ L
Sbjct: 919 TVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRV 978
Query: 3982 SD-DTKGFFDPNTHENLTYVQLLR 4004
+ + F+P T EN++ + ++
Sbjct: 979 ENLNIHQIFNPETKENISLPKAIK 1002
Score = 79.0 bits (193), Expect = 1e-13
Identities = 57/204 (27%), Positives = 95/204 (46%), Gaps = 26/204 (12%)
Query: 4356 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 4415
L I+GVL P Q S+ A+ G+L TA +LE Q TG +ID R
Sbjct: 804 LMADKAISGVL-----DPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLKRGK 858
Query: 4416 RLSVEEAVAAGVVG--------------------GEIQEKLLSAERAVTGYTDPYTGQQI 4455
++SV A G+V ++E+L+S + TG DP + +
Sbjct: 859 KVSVTLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDSKAPL 918
Query: 4456 SLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADP 4515
++ Q++ + L+ RE +RLL Q+ GG+I + R+ VD A+R G E++ L
Sbjct: 919 TVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRV 978
Query: 4516 SD-DTKGFFDPNTHENLTYVQLLR 4538
+ + F+P T EN++ + ++
Sbjct: 979 ENLNIHQIFNPETKENISLPKAIK 1002
Score = 78.6 bits (192), Expect = 2e-13
Identities = 57/198 (28%), Positives = 92/198 (46%), Gaps = 26/198 (13%)
Query: 4890 LEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNL 4949
L I+GVL P Q S+ A+ G+L TA +LE Q TG +ID R
Sbjct: 804 LMADKAISGVL-----DPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLKRGK 858
Query: 4950 RLSVEEAVAAGVVG--------------------GEIQEKLLSAERAVTGYTDPYTGQQI 4989
++SV A G+V ++E+L+S + TG DP + +
Sbjct: 859 KVSVTLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDSKAPL 918
Query: 4990 SLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADP 5049
++ Q++ + L+ RE +RLL Q+ GG+I + R+ VD A+R G E++ L
Sbjct: 919 TVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRV 978
Query: 5050 SD-DTKGFFDPNTHENLT 5066
+ + F+P T EN++
Sbjct: 979 ENLNIHQIFNPETKENIS 996
Score = 77.8 bits (190), Expect = 3e-13
Identities = 50/175 (28%), Positives = 92/175 (52%), Gaps = 4/175 (2%)
Query: 2249 MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVT 2308
M KG+L T LVLLE+Q +I P LS+EE + ++ ++ ++L + A+
Sbjct: 1 MQKGLLDQDTGLVLLESQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALA 60
Query: 2309 GYTDPYTGQ-QISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGY 2367
+ + +S+ +A++K +I G+++LEA +ATGG + + ++ A+ +G
Sbjct: 61 LISRLTESRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENCINLEEAFHQGL 120
Query: 2368 FDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML---QLAG 2419
++ VL +K DPNT E + + L++RC+ ++G +L QLAG
Sbjct: 121 ISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAG 175
Score = 77.8 bits (190), Expect = 3e-13
Identities = 95/423 (22%), Positives = 173/423 (40%), Gaps = 52/423 (12%)
Query: 1996 QLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFV 2055
+L+E+A L +L Q+ GG+ Q +L L A RG + + ++ +M + F
Sbjct: 718 ELLEEA-TLNVLSAQLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFF 776
Query: 2056 DPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAARDSEHIDDETRRALEAEQVEITVGRF 2115
D T E ++ E+ E +L V A + + D + L + + +TVG
Sbjct: 777 DSQTCESLTTEEVINEGLMDEK---LLHNVLMADKAISGVLDPRTQTLCSVKDAVTVG-- 831
Query: 2116 RGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQ 2175
LL+ E T + Q+V +R + L L
Sbjct: 832 ---------LLDKETATRILERQVVTGGIIDLKRGKKVSVTLASTL-------------- 868
Query: 2176 GIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKD 2235
G+ EL++ L+ GR ++ + + + +E T I
Sbjct: 869 GLVDVADQPELIN--------LEKASKGRDA-EKTVRERLISLQMETTGLI--------- 910
Query: 2236 QPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSE 2295
P + +++ Q++ +G+L A+ LL Q G +I + +RLSV+ G++G +
Sbjct: 911 DPDSKAPLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGED 970
Query: 2296 IQEKLLSAERA-VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHS 2354
+ EKL E + +P T + ISL +A++ DLI + + E Q TG +D +
Sbjct: 971 LAEKLKRVENLNIHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISG 1030
Query: 2355 HRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYM 2414
R+ + A + G N + P G DP + Y +L+++C D ++G
Sbjct: 1031 QRLTLAEAKKEGLL---TNEAVLSPG-MMHGIVDPENCRIVPYSELVKKCKIDIESGQRY 1086
Query: 2415 LQL 2417
L++
Sbjct: 1087 LEV 1089
Score = 77.4 bits (189), Expect = 3e-13
Identities = 50/170 (29%), Positives = 89/170 (52%), Gaps = 5/170 (2%)
Query: 4919 MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERA-- 4976
M KG+L T LVLLE+Q +I P LS+EE +A ++ ++ ++L + A
Sbjct: 1 MQKGLLDQDTGLVLLESQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALA 60
Query: 4977 -VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRR 5035
++ T+ + +S+ +A++K +I G+++LEA +ATGG + + ++ A+ +
Sbjct: 61 LISRLTE--SRGPLSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENCINLEEAFHQ 118
Query: 5036 GYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFL 5085
G ++ VL +K DPNT E + L L+QR + E+G L
Sbjct: 119 GLISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLL 168
Score = 77.0 bits (188), Expect = 4e-13
Identities = 81/339 (23%), Positives = 144/339 (42%), Gaps = 54/339 (15%)
Query: 56 SVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAA 115
SV A+E+ ++ +G +LEA ATGG + + +A QGL+ L L +
Sbjct: 73 SVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENCINLEEAFHQGLISAWLHSVLESY 132
Query: 116 ERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPAC 175
R + DP EK+ L + + +V + G L V+ GG+V G V+ A
Sbjct: 133 LRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMVSLKSGRKVSIFRAV 192
Query: 176 HQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALLPLKITF 235
+GL+DR+ +L E + G + ++P T RLT +E VR
Sbjct: 193 QEGLIDRQVTVRLLEAQLFAGGI--VDPRTGHRLT----VEEAVRH-------------- 232
Query: 236 RSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLLPE 295
++D+ D++ +R+ G G++
Sbjct: 233 ---------------NLIDQ--------------DMACAILIRQLQTG-----GIIDTVT 258
Query: 296 GHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELHEQ 355
G + + +A + L+ AL +LE+ + L+ P +G+ L + +A+ G+VS EL +
Sbjct: 259 GQRLTIDEAVSNDLVAAKIALVILESLWSFMGLLWPESGEILPITDALEQGIVSTELAHK 318
Query: 356 LLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRL 394
+L Q + P + + +A++ G++DR LA L
Sbjct: 319 ILSNRQHIKALFLPATTEILSWKKAIESGILDRDLANNL 357
Score = 77.0 bits (188), Expect = 4e-13
Identities = 107/469 (22%), Positives = 185/469 (39%), Gaps = 62/469 (13%)
Query: 1340 QAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKD 1399
Q ++ G+ + G LL + + G+V V L + G D+QT + LT +
Sbjct: 731 QLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLTTEEVI 790
Query: 1400 NKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPVST 1459
N+ D V V D T L + TV +D TA R ++ V T
Sbjct: 791 NEGLMDEKLLHNVLMADKAISGVLDPRTQTLCSVKDAVTVGLLDKETAT--RILERQVVT 848
Query: 1460 G------RFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSA--------V 1505
G R K SV+L L V + EL+ L ++ + + V
Sbjct: 849 GGIIDLKRGKKVSVTLASTL--GLVDVADQPELINLEKASKGRDAEKTVRERLISLQMET 906
Query: 1506 TALVEAAERQPL---QATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEV----- 1557
T L++ + PL Q+ RGL ++ A L Q++ + +S +V
Sbjct: 907 TGLIDPDSKAPLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGL 966
Query: 1558 --AEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFII 1615
++ + +E N I + T+E +S+P+A++ ++ + E QA TG +
Sbjct: 967 IGEDLAEKLKRVENLN-IHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFV 1025
Query: 1616 DPAENRKLTVEEAFKAGMFGKETY----------------------------VKLLSAER 1647
D ++LT+ EA K G+ E + + S +R
Sbjct: 1026 DLISGQRLTLAEAKKEGLLTNEAVLSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQR 1085
Query: 1648 AV-----TGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGIIDPVHSHRVPVD 1702
+ + D + + ++L QA+Q + +++LEAQ TGGIID R+ +
Sbjct: 1086 YLEVIPFSDIKDGVSDKVLTLSQAIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLA 1145
Query: 1703 VAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDPE 1751
A DE M RI+A G D + + +T ++ +E+ + PE
Sbjct: 1146 SALEEKLVDENMVRIIASHQVLNGGIVDIFSDQRVTLVEAIEKRLISPE 1194
Score = 75.1 bits (183), Expect = 2e-12
Identities = 68/273 (24%), Positives = 117/273 (42%), Gaps = 48/273 (17%)
Query: 4854 SELHTSGILGPETLRDLA--QGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQE 4911
S++ SG++ PET +L+ +G +M R L+ + L ++
Sbjct: 17 SQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALALISRLTESRGP----- 71
Query: 4912 KMSIYQAMWKGVLRPGTALVLLEAQAATG-FVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 4970
+S+ +A+ K ++ L +LEA ATG F + P N +++EEA G++ + L
Sbjct: 72 -LSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENC-INLEEAFHQGLISAWLHSVL 129
Query: 4971 LSAERAVTGYTDPYT--------------------------------------GQQISLF 4992
S R DP T G+++S+F
Sbjct: 130 ESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMVSLKSGRKVSIF 189
Query: 4993 QAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDD 5052
+A+Q+ LI R+ +RLLEAQ+ GG++DP HR+ V+ A R D++M +
Sbjct: 190 RAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAILIRQLQ 249
Query: 5053 TKGFFDPNTHENLTYLQLLQRATLDPETGLLFL 5085
T G D T + LT + + + + L+ L
Sbjct: 250 TGGIIDTVTGQRLTIDEAVSNDLVAAKIALVIL 282
Score = 74.3 bits (181), Expect = 3e-12
Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 10/235 (4%)
Query: 2718 SELHTSGILGPETLRDLA--QGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQE 2775
S++ SG++ PET +L+ +G +M R L+ + L ++
Sbjct: 17 SQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALALISRLTESRGP----- 71
Query: 2776 KMSIYQAMWKGVLRPGTALVLLEAQAATG-FVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 2834
+S+ +A+ K ++ L +LEA ATG F + P N +++EEA G++ + L
Sbjct: 72 -LSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENC-INLEEAFHQGLISAWLHSVL 129
Query: 2835 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 2894
S R DP T ++I L MQ+ ++ +E G +LL + GG++ +V +
Sbjct: 130 ESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMVSLKSGRKVSIF 189
Query: 2895 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML 2949
A + G D ++ L + G DP T LT + +R + D D +L
Sbjct: 190 RAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAIL 244
Score = 74.3 bits (181), Expect = 3e-12
Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 10/235 (4%)
Query: 3252 SELHTSGILGPETLRDLA--QGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQE 3309
S++ SG++ PET +L+ +G +M R L+ + L ++
Sbjct: 17 SQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALALISRLTESRGP----- 71
Query: 3310 KMSIYQAMWKGVLRPGTALVLLEAQAATG-FVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 3368
+S+ +A+ K ++ L +LEA ATG F + P N +++EEA G++ + L
Sbjct: 72 -LSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENC-INLEEAFHQGLISAWLHSVL 129
Query: 3369 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 3428
S R DP T ++I L MQ+ ++ +E G +LL + GG++ +V +
Sbjct: 130 ESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMVSLKSGRKVSIF 189
Query: 3429 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML 3483
A + G D ++ L + G DP T LT + +R + D D +L
Sbjct: 190 RAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAIL 244
Score = 74.3 bits (181), Expect = 3e-12
Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 10/235 (4%)
Query: 3786 SELHTSGILGPETLRDLA--QGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQE 3843
S++ SG++ PET +L+ +G +M R L+ + L ++
Sbjct: 17 SQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALALISRLTESRGP----- 71
Query: 3844 KMSIYQAMWKGVLRPGTALVLLEAQAATG-FVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 3902
+S+ +A+ K ++ L +LEA ATG F + P N +++EEA G++ + L
Sbjct: 72 -LSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENC-INLEEAFHQGLISAWLHSVL 129
Query: 3903 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 3962
S R DP T ++I L MQ+ ++ +E G +LL + GG++ +V +
Sbjct: 130 ESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMVSLKSGRKVSIF 189
Query: 3963 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML 4017
A + G D ++ L + G DP T LT + +R + D D +L
Sbjct: 190 RAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAIL 244
Score = 74.3 bits (181), Expect = 3e-12
Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 10/235 (4%)
Query: 4320 SELHTSGILGPETLRDLA--QGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQE 4377
S++ SG++ PET +L+ +G +M R L+ + L ++
Sbjct: 17 SQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALALISRLTESRGP----- 71
Query: 4378 KMSIYQAMWKGVLRPGTALVLLEAQAATG-FVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 4436
+S+ +A+ K ++ L +LEA ATG F + P N +++EEA G++ + L
Sbjct: 72 -LSVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENC-INLEEAFHQGLISAWLHSVL 129
Query: 4437 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 4496
S R DP T ++I L MQ+ ++ +E G +LL + GG++ +V +
Sbjct: 130 ESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMVSLKSGRKVSIF 189
Query: 4497 VAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML 4551
A + G D ++ L + G DP T LT + +R + D D +L
Sbjct: 190 RAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAIL 244
Score = 72.0 bits (175), Expect = 1e-11
Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 44/252 (17%)
Query: 2184 SELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKM 2243
S+++ S +I E ++L + L+ ++ E +A ++ + G +
Sbjct: 17 SQVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALA-LISRLTESRG---PL 72
Query: 2244 SIYQAMWKGVLRPGTALVLLEAQAATG-FVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLS 2302
S+ +A+ K ++ L +LEA ATG F + P N +++EE G++ + + L S
Sbjct: 73 SVVEAIEKRIISETVGLKILEAHLATGGFSLSPSENC-INLEEAFHQGLISAWLHSVLES 131
Query: 2303 AERAVTGYTDPYT--------------------------------------GQQISLFQA 2324
R DP T G+++S+F+A
Sbjct: 132 YLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMVSLKSGRKVSIFRA 191
Query: 2325 MQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTK 2384
+Q+ LI R+ +RLLEAQ+ GG++DP HR+ V+ A R D++M + T
Sbjct: 192 VQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAILIRQLQTG 251
Query: 2385 GFFDPNTHENLT 2396
G D T + LT
Sbjct: 252 GIIDTVTGQRLT 263
Score = 71.2 bits (173), Expect = 2e-11
Identities = 49/182 (26%), Positives = 89/182 (48%), Gaps = 5/182 (2%)
Query: 4907 PGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEI 4966
P + +++ Q++ +G+L A+ LL Q G +I + +RLSV+ A G++G ++
Sbjct: 912 PDSKAPLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDL 971
Query: 4967 QEKLLSAERA-VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSH 5025
EKL E + +P T + ISL +A++ DLI + + E Q TG +D +
Sbjct: 972 AEKLKRVENLNIHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQ 1031
Query: 5026 RVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFL 5085
R+ + A + G N + P G DP + Y +L+++ +D E+G +L
Sbjct: 1032 RLTLAEAKKEGLL---TNEAVLSPG-MMHGIVDPENCRIVPYSELVKKCKIDIESGQRYL 1087
Query: 5086 SL 5087
+
Sbjct: 1088 EV 1089
Score = 70.9 bits (172), Expect = 3e-11
Identities = 49/182 (26%), Positives = 89/182 (48%), Gaps = 5/182 (2%)
Query: 2771 PGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEI 2830
P + +++ Q++ +G+L A+ LL Q G +I + +RLSV+ A G++G ++
Sbjct: 912 PDSKAPLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDL 971
Query: 2831 QEKLLSAERA-VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSH 2889
EKL E + +P T + ISL +A++ DLI + + E Q TG +D +
Sbjct: 972 AEKLKRVENLNIHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQ 1031
Query: 2890 RVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML 2949
R+ + A + G N + P G DP + Y +L+++C D ++G L
Sbjct: 1032 RLTLAEAKKEGLL---TNEAVLSPG-MMHGIVDPENCRIVPYSELVKKCKIDIESGQRYL 1087
Query: 2950 QL 2951
++
Sbjct: 1088 EV 1089
Score = 70.9 bits (172), Expect = 3e-11
Identities = 49/182 (26%), Positives = 89/182 (48%), Gaps = 5/182 (2%)
Query: 3305 PGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEI 3364
P + +++ Q++ +G+L A+ LL Q G +I + +RLSV+ A G++G ++
Sbjct: 912 PDSKAPLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDL 971
Query: 3365 QEKLLSAERA-VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSH 3423
EKL E + +P T + ISL +A++ DLI + + E Q TG +D +
Sbjct: 972 AEKLKRVENLNIHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQ 1031
Query: 3424 RVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML 3483
R+ + A + G N + P G DP + Y +L+++C D ++G L
Sbjct: 1032 RLTLAEAKKEGLL---TNEAVLSPG-MMHGIVDPENCRIVPYSELVKKCKIDIESGQRYL 1087
Query: 3484 QL 3485
++
Sbjct: 1088 EV 1089
Score = 70.9 bits (172), Expect = 3e-11
Identities = 49/182 (26%), Positives = 89/182 (48%), Gaps = 5/182 (2%)
Query: 3839 PGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEI 3898
P + +++ Q++ +G+L A+ LL Q G +I + +RLSV+ A G++G ++
Sbjct: 912 PDSKAPLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDL 971
Query: 3899 QEKLLSAERA-VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSH 3957
EKL E + +P T + ISL +A++ DLI + + E Q TG +D +
Sbjct: 972 AEKLKRVENLNIHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQ 1031
Query: 3958 RVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML 4017
R+ + A + G N + P G DP + Y +L+++C D ++G L
Sbjct: 1032 RLTLAEAKKEGLL---TNEAVLSPG-MMHGIVDPENCRIVPYSELVKKCKIDIESGQRYL 1087
Query: 4018 QL 4019
++
Sbjct: 1088 EV 1089
Score = 70.9 bits (172), Expect = 3e-11
Identities = 49/182 (26%), Positives = 89/182 (48%), Gaps = 5/182 (2%)
Query: 4373 PGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEI 4432
P + +++ Q++ +G+L A+ LL Q G +I + +RLSV+ A G++G ++
Sbjct: 912 PDSKAPLTVVQSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDL 971
Query: 4433 QEKLLSAERA-VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSH 4491
EKL E + +P T + ISL +A++ DLI + + E Q TG +D +
Sbjct: 972 AEKLKRVENLNIHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQ 1031
Query: 4492 RVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYML 4551
R+ + A + G N + P G DP + Y +L+++C D ++G L
Sbjct: 1032 RLTLAEAKKEGLL---TNEAVLSPG-MMHGIVDPENCRIVPYSELVKKCKIDIESGQRYL 1087
Query: 4552 QL 4553
++
Sbjct: 1088 EV 1089
Score = 68.9 bits (167), Expect = 1e-10
Identities = 52/196 (26%), Positives = 90/196 (45%), Gaps = 20/196 (10%)
Query: 4911 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 4970
+K+ + +A+ +G++ TA+ L+E D L+ EE + G++ ++ +
Sbjct: 744 QKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLTTEEVINEGLMDEKLLHNV 803
Query: 4971 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 5030
L A++A++G DP T S+ A+ L+ +E R+LE Q+ TGG+ID +V V
Sbjct: 804 LMADKAISGVLDPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLKRGKKVSVT 863
Query: 5031 VAYRRGYFD-----EEMNRVLADPSDD---------------TKGFFDPNTHENLTYLQL 5070
+A G D E +N A D T G DP++ LT +Q
Sbjct: 864 LASTLGLVDVADQPELINLEKASKGRDAEKTVRERLISLQMETTGLIDPDSKAPLTVVQS 923
Query: 5071 LQRATLDPETGLLFLS 5086
+ R L+ E + L+
Sbjct: 924 IDRGLLEREEAVRLLT 939
Score = 68.6 bits (166), Expect = 2e-10
Identities = 50/179 (27%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Query: 38 PQARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSK 97
P + G+ SG+ S++ A+++GL+ + LLEAQ GG+VD G L V +
Sbjct: 169 PVKQLAGGMVSLKSGRKVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEE 228
Query: 98 ALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLAT 157
A++ L+ ++ +L + T G D G++L + +A+ ++V + LE +
Sbjct: 229 AVRHNLIDQDMACAILIRQLQTGGIIDTVTGQRLTIDEAVSNDLVAAKIALVILESLWSF 288
Query: 158 GGLVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLE 216
GL+ P G ++ A QG++ E HK+ L FL P T E L++ + +E
Sbjct: 289 MGLLWPESGEILPITDALEQGIVSTELAHKILSNRQHIKAL-FL-PATTEILSWKKAIE 345
Score = 67.0 bits (162), Expect = 5e-10
Identities = 63/278 (22%), Positives = 123/278 (44%), Gaps = 23/278 (8%)
Query: 4821 LPDLVAVLTR---------VIEETEERLSKVSFRGLRRQVSASELHTSGI-LGPETLRDL 4870
L D +A+++R V+E E+R+ + GL+ + + L T G L P
Sbjct: 55 LQDALALISRLTESRGPLSVVEAIEKRIISETV-GLK--ILEAHLATGGFSLSP------ 105
Query: 4871 AQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKD--QPGRQEKMSIYQAMWKGVLRPGT 4928
++ L+E + +L S + L +K+ P EK+ + M + ++ +
Sbjct: 106 SENCINLEEAFHQGLISAWLH--SVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQES 163
Query: 4929 ALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQ 4988
LL + G ++ ++S+ AV G++ ++ +LL A+ G DP TG +
Sbjct: 164 GFKLLPVKQLAGGMVSLKSGRKVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHR 223
Query: 4989 ISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 5048
+++ +A++ +LI ++ +L Q+ TGG+ID V R+ +D A ++ V+ +
Sbjct: 224 LTVEEAVRHNLIDQDMACAILIRQLQTGGIIDTVTGQRLTIDEAVSNDLVAAKIALVILE 283
Query: 5049 PSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLS 5086
G P + E L L++ + E LS
Sbjct: 284 SLWSFMGLLWPESGEILPITDALEQGIVSTELAHKILS 321
Score = 62.8 bits (151), Expect = 9e-09
Identities = 57/240 (23%), Positives = 106/240 (44%), Gaps = 9/240 (3%)
Query: 45 GVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGLV 104
G + S ++ A QGL+ A L L + L+D + + + +Q+ +V
Sbjct: 100 GFSLSPSENCINLEEAFHQGLISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIV 159
Query: 105 GLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPA 164
E KLL ++ G G K+++F+A+ + ++DR + LE QL GG+VDP
Sbjct: 160 HQESGFKLLPVKQLAGGMVSLKSGRKVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPR 219
Query: 165 QGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCVRAPGS 224
G + E A L+D++ + + TG + ++ T +RLT + + + A
Sbjct: 220 TGHRLTVEEAVRHNLIDQDMACAILIRQLQTGGI--IDTVTGQRLTIDEAVSNDLVAAKI 277
Query: 225 GLALLPLKITFRSM-----GGAVSAAELLEVGILDEQAVQGLREGR--LAAVDVSARAEV 277
L +L +F + G + + LE GI+ + + R + A+ + A E+
Sbjct: 278 ALVILESLWSFMGLLWPESGEILPITDALEQGIVSTELAHKILSNRQHIKALFLPATTEI 337
Score = 62.4 bits (150), Expect = 1e-08
Identities = 38/167 (22%), Positives = 77/167 (46%)
Query: 2237 PGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEI 2296
P EK+ + M + ++ + LL + G ++ ++S+ V G++ ++
Sbjct: 142 PNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMVSLKSGRKVSIFRAVQEGLIDRQV 201
Query: 2297 QEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHR 2356
+LL A+ G DP TG ++++ +A++ +LI ++ +L Q+ TGG+ID V R
Sbjct: 202 TVRLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAILIRQLQTGGIIDTVTGQR 261
Query: 2357 VPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRR 2403
+ +D A ++ V+ + G P + E L L +
Sbjct: 262 LTIDEAVSNDLVAAKIALVILESLWSFMGLLWPESGEILPITDALEQ 308
Score = 62.0 bits (149), Expect = 1e-08
Identities = 97/456 (21%), Positives = 192/456 (42%), Gaps = 80/456 (17%)
Query: 940 SGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYG 999
SG+ + L + +LL L +L AQ G I + + L ++EA+ RG+V
Sbjct: 705 SGREIFLSCSHPLELL-EEATLNVLSAQLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAV 763
Query: 1000 RLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLP 1059
+L GF D + + ++ + + +GL+ + +L A A G++DP +
Sbjct: 764 KLMEKLNMFQGFFDSQTCESLTTEEVINEGLMDEKLLHNVLMADKAISGVLDPRTQTLCS 823
Query: 1060 MPVAIQRGYVDQEMETALSSSSETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESA 1119
+ A+ G +D+E T ++LE R +G
Sbjct: 824 VKDAVTVGLLDKETAT---------------------RILE---RQVVTG--------GI 851
Query: 1120 PALPTEEQVQRSLQAVPGAKDGTSLWDLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASV 1179
L ++V +L + G D +L++ E+ +G ++ TV + L S+
Sbjct: 852 IDLKRGKKVSVTLASTLGLVDVADQPELIN----LEKASKG-----RDAEKTVRERLISL 902
Query: 1180 QRWVQETKLLAQARVMVPGPRGEVPAVWLLDAGIITQETLEALAQGTQSPAQVAEQPAVK 1239
Q ++ T L+ P + + V +D G++ +E EA+ T+ QV +
Sbjct: 903 Q--METTGLID------PDSKAPLTVVQSIDRGLLERE--EAVRLLTK---QVVD----- 944
Query: 1240 ACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQ-VASGFLVDPLNNQRL 1298
G++ SG + S+ A R GL+ L ++L + + + +P + +
Sbjct: 945 ---------GGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRVENLNIHQIFNPETKENI 995
Query: 1299 SVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQV 1358
S+ A+K+ L+ +L ++ + + + D S L+L +A ++GL+ NE +
Sbjct: 996 SLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQRLTLAEAKKEGLL-TNEAV----- 1049
Query: 1359 QLATG---GVVDPVHGVHLPQAAACRLGLLDTQTSQ 1391
L+ G G+VDP + +P + + +D ++ Q
Sbjct: 1050 -LSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQ 1084
Score = 53.9 bits (128), Expect = 4e-06
Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
Query: 39 QARSIAGVYVEA-SGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSK 97
+A+ AG V+ +G +V A+ L+ + A+L Q TGG++D GQ L + +
Sbjct: 207 EAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAILIRQLQTGGIIDTVTGQRLTIDE 266
Query: 98 ALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLAT 157
A+ LV ++ +L + + G P GE L + A+ + +V L L +
Sbjct: 267 AVSNDLVAAKIALVILESLWSFMGLLWPESGEILPITDALEQGIVSTELAHKILSNRQHI 326
Query: 158 GGLVDPAQGVLVAPEPACHQGLLDRETWHKLSEL 191
L PA +++ + A G+LDR+ + L +
Sbjct: 327 KALFLPATTEILSWKKAIESGILDRDLANNLKSI 360
Score = 50.8 bits (120), Expect = 3e-05
Identities = 41/146 (28%), Positives = 75/146 (51%), Gaps = 10/146 (6%)
Query: 2724 GILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKD-QPGRQEK-MSIYQ 2781
GI+ PE R + + +++S +RYLE ++P D + G +K +++ Q
Sbjct: 1057 GIVDPENCRIVPYSELVKKCKIDIESGQRYLE--------VIPFSDIKDGVSDKVLTLSQ 1108
Query: 2782 AMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAV 2841
A+ G + + L +LEAQA TG +ID RL++ A+ +V + + S +
Sbjct: 1109 AIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQVLN 1168
Query: 2842 TGYTDPYTGQQISLFQAMQKDLIVRE 2867
G D ++ Q+++L +A++K LI E
Sbjct: 1169 GGIVDIFSDQRVTLVEAIEKRLISPE 1194
Score = 50.8 bits (120), Expect = 3e-05
Identities = 41/146 (28%), Positives = 75/146 (51%), Gaps = 10/146 (6%)
Query: 3258 GILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKD-QPGRQEK-MSIYQ 3315
GI+ PE R + + +++S +RYLE ++P D + G +K +++ Q
Sbjct: 1057 GIVDPENCRIVPYSELVKKCKIDIESGQRYLE--------VIPFSDIKDGVSDKVLTLSQ 1108
Query: 3316 AMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAV 3375
A+ G + + L +LEAQA TG +ID RL++ A+ +V + + S +
Sbjct: 1109 AIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQVLN 1168
Query: 3376 TGYTDPYTGQQISLFQAMQKDLIVRE 3401
G D ++ Q+++L +A++K LI E
Sbjct: 1169 GGIVDIFSDQRVTLVEAIEKRLISPE 1194
Score = 50.8 bits (120), Expect = 3e-05
Identities = 41/146 (28%), Positives = 75/146 (51%), Gaps = 10/146 (6%)
Query: 3792 GILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKD-QPGRQEK-MSIYQ 3849
GI+ PE R + + +++S +RYLE ++P D + G +K +++ Q
Sbjct: 1057 GIVDPENCRIVPYSELVKKCKIDIESGQRYLE--------VIPFSDIKDGVSDKVLTLSQ 1108
Query: 3850 AMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAV 3909
A+ G + + L +LEAQA TG +ID RL++ A+ +V + + S +
Sbjct: 1109 AIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQVLN 1168
Query: 3910 TGYTDPYTGQQISLFQAMQKDLIVRE 3935
G D ++ Q+++L +A++K LI E
Sbjct: 1169 GGIVDIFSDQRVTLVEAIEKRLISPE 1194
Score = 50.8 bits (120), Expect = 3e-05
Identities = 41/146 (28%), Positives = 75/146 (51%), Gaps = 10/146 (6%)
Query: 4326 GILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKD-QPGRQEK-MSIYQ 4383
GI+ PE R + + +++S +RYLE ++P D + G +K +++ Q
Sbjct: 1057 GIVDPENCRIVPYSELVKKCKIDIESGQRYLE--------VIPFSDIKDGVSDKVLTLSQ 1108
Query: 4384 AMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAV 4443
A+ G + + L +LEAQA TG +ID RL++ A+ +V + + S +
Sbjct: 1109 AIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQVLN 1168
Query: 4444 TGYTDPYTGQQISLFQAMQKDLIVRE 4469
G D ++ Q+++L +A++K LI E
Sbjct: 1169 GGIVDIFSDQRVTLVEAIEKRLISPE 1194
Score = 50.8 bits (120), Expect = 3e-05
Identities = 41/146 (28%), Positives = 75/146 (51%), Gaps = 10/146 (6%)
Query: 4860 GILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKD-QPGRQEK-MSIYQ 4917
GI+ PE R + + +++S +RYLE ++P D + G +K +++ Q
Sbjct: 1057 GIVDPENCRIVPYSELVKKCKIDIESGQRYLE--------VIPFSDIKDGVSDKVLTLSQ 1108
Query: 4918 AMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAV 4977
A+ G + + L +LEAQA TG +ID RL++ A+ +V + + S +
Sbjct: 1109 AIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQVLN 1168
Query: 4978 TGYTDPYTGQQISLFQAMQKDLIVRE 5003
G D ++ Q+++L +A++K LI E
Sbjct: 1169 GGIVDIFSDQRVTLVEAIEKRLISPE 1194
Score = 48.9 bits (115), Expect = 1e-04
Identities = 125/649 (19%), Positives = 219/649 (33%), Gaps = 181/649 (27%)
Query: 316 LPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQI 375
L +L AQ + TGQ+L ++EA+ G+V +L+ G D + +
Sbjct: 725 LNVLSAQLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESL 784
Query: 376 PLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLSQA 435
+ + +GL+D L +L A A G LD TQ S
Sbjct: 785 TTEEVINEGLMDEKLLHNVLMADKAIS-------------------GVLDPRTQTLCSVK 825
Query: 436 GSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTAT 495
+ + G + D ET L RQ ++
Sbjct: 826 DAVTVG--------------LLDKETATRILE--------------------RQVVTGGI 851
Query: 496 ATVSVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAELSATLEQAAAT 555
+ RG+ VS+ S+ +A Q + L + T+ + +
Sbjct: 852 IDLK----RGKKVSV------TLASTLGLVDVADQPELINLEKASKGRDAEKTVRERLIS 901
Query: 556 ARVTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASAQRYLQGTGCIAGL 615
++ +GL D + L + ID+ L ER E + K V
Sbjct: 902 LQMETTGLIDPDSKAPLTVVQSIDRGLLEREEAVRLLTKQV------------------- 942
Query: 616 LLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGP 675
G II + SV+ A R +IG
Sbjct: 943 ---------------------------------VDGGIIHHISGMRLSVDNAFRHGLIGE 969
Query: 676 DVFAKLLSAERA-VTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVH 734
D+ KL E + +P T + ISL +A++ LI + + E Q TG +D +
Sbjct: 970 DLAEKLKRVENLNIHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLIS 1029
Query: 735 SHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETG-- 792
R+ + A + G + N +L P G DP + Y +L+++C D E+G
Sbjct: 1030 GQRLTLAEAKKEGL---LTNEAVLSPG-MMHGIVDPENCRIVPYSELVKKCKIDIESGQR 1085
Query: 793 -LYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLL 851
L ++P S + + D L +++ G+
Sbjct: 1086 YLEVIPFSDIKDGVSDKVL-----TLSQAIQLGK-------------------------- 1114
Query: 852 RRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTI 911
V K+LEA+ I+ A R+T+ LE ++D+ ++ + + +
Sbjct: 1115 -------VDFASTLKVLEAQA-NTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQV 1166
Query: 912 SPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVA 960
GG+ + S QR++L +A+ ++L+ P +A
Sbjct: 1167 -------------------LNGGIVDIFSDQRVTLVEAIEKRLISPELA 1196
Score = 48.5 bits (114), Expect = 2e-04
Identities = 46/206 (22%), Positives = 88/206 (42%), Gaps = 33/206 (16%)
Query: 4907 PGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGE- 4965
P +E +S+ +A+ ++ + E QA TG +D + RL++ EA G++ E
Sbjct: 989 PETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQRLTLAEAKKEGLLTNEA 1048
Query: 4966 -----IQEKLLSAERA-VTGYT--------DPYTGQQ------------------ISLFQ 4993
+ ++ E + Y+ D +GQ+ ++L Q
Sbjct: 1049 VLSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYLEVIPFSDIKDGVSDKVLTLSQ 1108
Query: 4994 AMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDT 5053
A+Q + +++LEAQ TGG+ID R+ + A DE M R++A
Sbjct: 1109 AIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQVLN 1168
Query: 5054 KGFFDPNTHENLTYLQLLQRATLDPE 5079
G D + + +T ++ +++ + PE
Sbjct: 1169 GGIVDIFSDQRVTLVEAIEKRLISPE 1194
Score = 46.6 bits (109), Expect = 6e-04
Identities = 53/239 (22%), Positives = 101/239 (42%), Gaps = 39/239 (16%)
Query: 2771 PGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGE- 2829
P +E +S+ +A+ ++ + E QA TG +D + RL++ EA G++ E
Sbjct: 989 PETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQRLTLAEAKKEGLLTNEA 1048
Query: 2830 -----IQEKLLSAERA-VTGYT--------DPYTGQQ------------------ISLFQ 2857
+ ++ E + Y+ D +GQ+ ++L Q
Sbjct: 1049 VLSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYLEVIPFSDIKDGVSDKVLTLSQ 1108
Query: 2858 AMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDT 2917
A+Q + +++LEAQ TGG+ID R+ + A DE M R++A
Sbjct: 1109 AIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQVLN 1168
Query: 2918 KGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELR-----CALRD 2971
G D + + +T V+ + + + P+ M+Q+ + H+ E + CAL++
Sbjct: 1169 GGIVDIFSDQRVTLVEAIEKRLISPELA-NMIQIDSSEFSDHRAQIEKQEGIEVCALQN 1226
Score = 46.6 bits (109), Expect = 6e-04
Identities = 53/239 (22%), Positives = 101/239 (42%), Gaps = 39/239 (16%)
Query: 3305 PGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGE- 3363
P +E +S+ +A+ ++ + E QA TG +D + RL++ EA G++ E
Sbjct: 989 PETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQRLTLAEAKKEGLLTNEA 1048
Query: 3364 -----IQEKLLSAERA-VTGYT--------DPYTGQQ------------------ISLFQ 3391
+ ++ E + Y+ D +GQ+ ++L Q
Sbjct: 1049 VLSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYLEVIPFSDIKDGVSDKVLTLSQ 1108
Query: 3392 AMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDT 3451
A+Q + +++LEAQ TGG+ID R+ + A DE M R++A
Sbjct: 1109 AIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQVLN 1168
Query: 3452 KGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELR-----CALRD 3505
G D + + +T V+ + + + P+ M+Q+ + H+ E + CAL++
Sbjct: 1169 GGIVDIFSDQRVTLVEAIEKRLISPELA-NMIQIDSSEFSDHRAQIEKQEGIEVCALQN 1226
Score = 46.6 bits (109), Expect = 6e-04
Identities = 53/239 (22%), Positives = 101/239 (42%), Gaps = 39/239 (16%)
Query: 3839 PGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGE- 3897
P +E +S+ +A+ ++ + E QA TG +D + RL++ EA G++ E
Sbjct: 989 PETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQRLTLAEAKKEGLLTNEA 1048
Query: 3898 -----IQEKLLSAERA-VTGYT--------DPYTGQQ------------------ISLFQ 3925
+ ++ E + Y+ D +GQ+ ++L Q
Sbjct: 1049 VLSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYLEVIPFSDIKDGVSDKVLTLSQ 1108
Query: 3926 AMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDT 3985
A+Q + +++LEAQ TGG+ID R+ + A DE M R++A
Sbjct: 1109 AIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQVLN 1168
Query: 3986 KGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELR-----CALRD 4039
G D + + +T V+ + + + P+ M+Q+ + H+ E + CAL++
Sbjct: 1169 GGIVDIFSDQRVTLVEAIEKRLISPELA-NMIQIDSSEFSDHRAQIEKQEGIEVCALQN 1226
Score = 46.6 bits (109), Expect = 6e-04
Identities = 53/239 (22%), Positives = 101/239 (42%), Gaps = 39/239 (16%)
Query: 4373 PGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGE- 4431
P +E +S+ +A+ ++ + E QA TG +D + RL++ EA G++ E
Sbjct: 989 PETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQRLTLAEAKKEGLLTNEA 1048
Query: 4432 -----IQEKLLSAERA-VTGYT--------DPYTGQQ------------------ISLFQ 4459
+ ++ E + Y+ D +GQ+ ++L Q
Sbjct: 1049 VLSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYLEVIPFSDIKDGVSDKVLTLSQ 1108
Query: 4460 AMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDT 4519
A+Q + +++LEAQ TGG+ID R+ + A DE M R++A
Sbjct: 1109 AIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQVLN 1168
Query: 4520 KGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELR-----CALRD 4573
G D + + +T V+ + + + P+ M+Q+ + H+ E + CAL++
Sbjct: 1169 GGIVDIFSDQRVTLVEAIEKRLISPELA-NMIQIDSSEFSDHRAQIEKQEGIEVCALQN 1226
Score = 41.6 bits (96), Expect = 0.020
Identities = 30/110 (27%), Positives = 57/110 (51%), Gaps = 3/110 (2%)
Query: 4944 DPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVRE 5003
D V + L++ +A+ G V K+L A+ G D TG++++L A+++ L V E
Sbjct: 1097 DGVSDKVLTLSQAIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKL-VDE 1155
Query: 5004 HGIRLLEA-QIATGGVIDPVHSHRVPVDVAYRRGYFDEEM-NRVLADPSD 5051
+ +R++ + Q+ GG++D RV + A + E+ N + D S+
Sbjct: 1156 NMVRIIASHQVLNGGIVDIFSDQRVTLVEAIEKRLISPELANMIQIDSSE 1205
Score = 35.4 bits (80), Expect = 1.5
Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 4/118 (3%)
Query: 4970 LLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPV 5029
+LSA+ G TGQ++ L +A+ + ++ ++L+E G D +
Sbjct: 727 VLSAQLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDSQTCESLTT 786
Query: 5030 DVAYRRGYFDEEM--NRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFL 5085
+ G DE++ N ++AD + G DP T + + LD ET L
Sbjct: 787 EEVINEGLMDEKLLHNVLMADKA--ISGVLDPRTQTLCSVKDAVTVGLLDKETATRIL 842
Score = 35.0 bits (79), Expect = 1.9
Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 1/114 (0%)
Query: 3398 IVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDP 3457
++ E + +L AQ+ GG+ ++ ++ A RG L + + +GFFD
Sbjct: 719 LLEEATLNVLSAQLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDS 778
Query: 3458 NTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPG 3511
T E+LT +++ + D +L S V + C+++DA VT G
Sbjct: 779 QTCESLTTEEVINEGLMDEKLLHNVLMADKAISGVLDPRTQTLCSVKDA-VTVG 831
Score = 34.3 bits (77), Expect = 3.3
Identities = 19/78 (24%), Positives = 37/78 (47%)
Query: 5000 IVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDP 5059
++ E + +L AQ+ GG+ ++ ++ A RG L + + +GFFD
Sbjct: 719 LLEEATLNVLSAQLLDGGIFHEQTGQKLLLNEAISRGIVPSHTAVKLMEKLNMFQGFFDS 778
Query: 5060 NTHENLTYLQLLQRATLD 5077
T E+LT +++ +D
Sbjct: 779 QTCESLTTEEVINEGLMD 796
>gi|156104874 envoplakin [Homo sapiens]
Length = 2033
Score = 126 bits (316), Expect = 6e-28
Identities = 71/191 (37%), Positives = 111/191 (58%)
Query: 1573 IAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPAENRKLTVEEAFKAG 1632
IAG+ T + SI A+ +++L P T LLEAQAATG I+D + +V +A + G
Sbjct: 1827 IAGIYDTTTDNKCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAMERG 1886
Query: 1633 MFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGIID 1692
+ + +LL+A++A TG DP T +++S+ +A+QK + RE + L+ Q TGG+ID
Sbjct: 1887 LIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLTGGLID 1946
Query: 1693 PVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDPET 1752
P + R+P+ A G EE+ ++L D S K DP + E L+Y + + RC +DP +
Sbjct: 1947 PKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCRKDPLS 2006
Query: 1753 GLYLLQIIKKG 1763
GL LL +G
Sbjct: 2007 GLLLLPAALEG 2017
Score = 122 bits (305), Expect = 1e-26
Identities = 74/196 (37%), Positives = 111/196 (56%), Gaps = 5/196 (2%)
Query: 2760 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 2819
IAG+ D K SI A+ K +L P T LLEAQAATG ++D + R SV +
Sbjct: 1827 IAGIYDTTTDN-----KCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHK 1881
Query: 2820 AVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 2879
A+ G++ ++LL+A++A TG DP T +++S+ +A+QK + RE + L+ Q T
Sbjct: 1882 AMERGLIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLT 1941
Query: 2880 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCV 2939
GG+IDP + R+P+ A G EE+ ++L D S K DP + E L+Y + + RC
Sbjct: 1942 GGLIDPKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCR 2001
Query: 2940 PDPDTGLYMLQLAGRG 2955
DP +GL +L A G
Sbjct: 2002 KDPLSGLLLLPAALEG 2017
Score = 122 bits (305), Expect = 1e-26
Identities = 74/196 (37%), Positives = 111/196 (56%), Gaps = 5/196 (2%)
Query: 3294 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 3353
IAG+ D K SI A+ K +L P T LLEAQAATG ++D + R SV +
Sbjct: 1827 IAGIYDTTTDN-----KCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHK 1881
Query: 3354 AVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 3413
A+ G++ ++LL+A++A TG DP T +++S+ +A+QK + RE + L+ Q T
Sbjct: 1882 AMERGLIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLT 1941
Query: 3414 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCV 3473
GG+IDP + R+P+ A G EE+ ++L D S K DP + E L+Y + + RC
Sbjct: 1942 GGLIDPKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCR 2001
Query: 3474 PDPDTGLYMLQLAGRG 3489
DP +GL +L A G
Sbjct: 2002 KDPLSGLLLLPAALEG 2017
Score = 122 bits (305), Expect = 1e-26
Identities = 74/196 (37%), Positives = 111/196 (56%), Gaps = 5/196 (2%)
Query: 3828 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 3887
IAG+ D K SI A+ K +L P T LLEAQAATG ++D + R SV +
Sbjct: 1827 IAGIYDTTTDN-----KCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHK 1881
Query: 3888 AVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 3947
A+ G++ ++LL+A++A TG DP T +++S+ +A+QK + RE + L+ Q T
Sbjct: 1882 AMERGLIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLT 1941
Query: 3948 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCV 4007
GG+IDP + R+P+ A G EE+ ++L D S K DP + E L+Y + + RC
Sbjct: 1942 GGLIDPKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCR 2001
Query: 4008 PDPDTGLYMLQLAGRG 4023
DP +GL +L A G
Sbjct: 2002 KDPLSGLLLLPAALEG 2017
Score = 122 bits (305), Expect = 1e-26
Identities = 74/196 (37%), Positives = 111/196 (56%), Gaps = 5/196 (2%)
Query: 4362 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 4421
IAG+ D K SI A+ K +L P T LLEAQAATG ++D + R SV +
Sbjct: 1827 IAGIYDTTTDN-----KCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHK 1881
Query: 4422 AVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 4481
A+ G++ ++LL+A++A TG DP T +++S+ +A+QK + RE + L+ Q T
Sbjct: 1882 AMERGLIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLT 1941
Query: 4482 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCV 4541
GG+IDP + R+P+ A G EE+ ++L D S K DP + E L+Y + + RC
Sbjct: 1942 GGLIDPKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCR 2001
Query: 4542 PDPDTGLYMLQLAGRG 4557
DP +GL +L A G
Sbjct: 2002 KDPLSGLLLLPAALEG 2017
Score = 122 bits (305), Expect = 1e-26
Identities = 72/186 (38%), Positives = 108/186 (58%)
Query: 612 IAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAA 671
IAG+ + + SI A K +L P T LLEAQAATG I+D + + +SV +A+
Sbjct: 1827 IAGIYDTTTDNKCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAMERG 1886
Query: 672 VIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVID 731
+I +LL+A++A TG DP T +++S+ +A+QKG + RE + L+ Q TGG+ID
Sbjct: 1887 LIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLTGGLID 1946
Query: 732 PVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPET 791
P + R+P+ A G + L +L D S K DP + E L+Y + + RC +DP +
Sbjct: 1947 PKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCRKDPLS 2006
Query: 792 GLYLLP 797
GL LLP
Sbjct: 2007 GLLLLP 2012
Score = 120 bits (302), Expect = 3e-26
Identities = 73/195 (37%), Positives = 111/195 (56%), Gaps = 5/195 (2%)
Query: 4896 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 4955
IAG+ D K SI A+ K +L P T LLEAQAATG ++D + R SV +
Sbjct: 1827 IAGIYDTTTDN-----KCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHK 1881
Query: 4956 AVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 5015
A+ G++ ++LL+A++A TG DP T +++S+ +A+QK + RE + L+ Q T
Sbjct: 1882 AMERGLIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLT 1941
Query: 5016 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRAT 5075
GG+IDP + R+P+ A G EE+ ++L D S K DP + E L+Y + + R
Sbjct: 1942 GGLIDPKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCR 2001
Query: 5076 LDPETGLLFLSLSLQ 5090
DP +GLL L +L+
Sbjct: 2002 KDPLSGLLLLPAALE 2016
Score = 120 bits (301), Expect = 3e-26
Identities = 73/196 (37%), Positives = 111/196 (56%), Gaps = 5/196 (2%)
Query: 2226 IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEE 2285
IAG+ D K SI A+ K +L P T LLEAQAATG ++D + R SV +
Sbjct: 1827 IAGIYDTTTDN-----KCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHK 1881
Query: 2286 PVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIAT 2345
+ G++ + ++LL+A++A TG DP T +++S+ +A+QK + RE + L+ Q T
Sbjct: 1882 AMERGLIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLT 1941
Query: 2346 GGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCV 2405
GG+IDP + R+P+ A G EE+ ++L D S K DP + E L+Y + + RC
Sbjct: 1942 GGLIDPKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCR 2001
Query: 2406 PDPDTGLYMLQLAGRG 2421
DP +GL +L A G
Sbjct: 2002 KDPLSGLLLLPAALEG 2017
Score = 119 bits (299), Expect = 6e-26
Identities = 65/186 (34%), Positives = 107/186 (57%)
Query: 1899 IAGVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVG 1958
IAG+ +T S+ A K ++ LLEAQAATG ++D +R++ SV +A++ G
Sbjct: 1827 IAGIYDTTTDNKCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAMERG 1886
Query: 1959 LVNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVID 2018
L+ +RLL A++A TG DP T + + +A+QK + + L L+VQ TGG+ID
Sbjct: 1887 LIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLTGGLID 1946
Query: 2019 PQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDT 2078
P+ R+P++ A G + +++ L+ D+ K DP ++E++SY+E RCR +
Sbjct: 1947 PKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCRKDPLS 2006
Query: 2079 GWVLFP 2084
G +L P
Sbjct: 2007 GLLLLP 2012
Score = 118 bits (296), Expect = 1e-25
Identities = 67/186 (36%), Positives = 109/186 (58%)
Query: 1248 VAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVG 1307
+AG+ + K SI AV +L GQ+LLEAQ A+G +VD L+ +R SV A++ G
Sbjct: 1827 IAGIYDTTTDNKCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAMERG 1886
Query: 1308 LVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVD 1367
L+ +++L A++A G DP ++ LS+ +A++KG +P+ LP LQVQ TGG++D
Sbjct: 1887 LIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLTGGLID 1946
Query: 1368 PVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSET 1427
P +P A G++ + +Q+L K DP ++++++Y++ RC D +
Sbjct: 1947 PKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCRKDPLS 2006
Query: 1428 GLLLLP 1433
GLLLLP
Sbjct: 2007 GLLLLP 2012
Score = 109 bits (273), Expect = 6e-23
Identities = 78/223 (34%), Positives = 117/223 (52%), Gaps = 10/223 (4%)
Query: 8 PLPVPGTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAAMEQGLLP 67
PL P ST S + +LG G P IAG+Y + S+ A+ + +L
Sbjct: 1800 PLASPAPQSTSFFSP----SFSLGLGDDSFP----IAGIYDTTTDNKCSIKTAVAKNMLD 1851
Query: 68 AGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYG 127
GQ LLEAQAATGG+VDL + V KA+++GL+ ++LL A++A TG DP
Sbjct: 1852 PITGQKLLEAQAATGGIVDLLSRERYSVHKAMERGLIENTSTQRLLNAQKAFTGIEDPVT 1911
Query: 128 GEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLLDRETWHK 187
++L++ +A+ K + R L+VQ TGGL+DP + + + A G++ E
Sbjct: 1912 KKRLSVGEAVQKGWMPRESVLPHLQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELAQL 1971
Query: 188 LSELEPGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALLP 230
L + DL +P + ERL+Y + + RC + P SGL LLP
Sbjct: 1972 LQDESSYEKDL--TDPISKERLSYKEAMGRCRKDPLSGLLLLP 2012
Score = 105 bits (262), Expect = 1e-21
Identities = 65/186 (34%), Positives = 99/186 (53%), Gaps = 3/186 (1%)
Query: 932 VGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRG 991
+ G+ + + S+ A+ + +L P LLEAQAATG I+D S E SV +A+ RG
Sbjct: 1827 IAGIYDTTTDNKCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAMERG 1886
Query: 992 VVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIID 1051
++ RL A+ A G DP + K++SV +A++KG +P E L+ Q TGG+ID
Sbjct: 1887 LIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLTGGLID 1946
Query: 1052 PTSHHHLPMPVAIQRGYVDQEMETAL---SSSSETFPTPDGQGRTSYAQLLEECPRDETS 1108
P +P+ A+ G + +E+ L SS + P + R SY + + C +D S
Sbjct: 1947 PKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCRKDPLS 2006
Query: 1109 GLHLLP 1114
GL LLP
Sbjct: 2007 GLLLLP 2012
Score = 93.6 bits (231), Expect = 5e-18
Identities = 60/186 (32%), Positives = 98/186 (52%), Gaps = 5/186 (2%)
Query: 287 VAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAG 346
+AG+ +K S A +++L T LLEAQAAT +VD ++ +R V +A+ G
Sbjct: 1827 IAGIYDTTTDNKCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAMERG 1886
Query: 347 LVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVC 406
L+ ++LL A++A TG DP + ++ + +A++KG + R L L Q TGGL+
Sbjct: 1887 LIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLTGGLID 1946
Query: 407 PARRLRLPLEAALRCGCLDEDTQRQLSQAGSFSDG-----THGGLRYEQLLALCVTDPET 461
P R R+P++ AL G + E+ + L S+ + L Y++ + C DP +
Sbjct: 1947 PKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCRKDPLS 2006
Query: 462 GLAFLP 467
GL LP
Sbjct: 2007 GLLLLP 2012
Score = 55.5 bits (132), Expect = 1e-06
Identities = 44/145 (30%), Positives = 66/145 (45%), Gaps = 1/145 (0%)
Query: 278 RRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRL 337
++ LE + G+V L + S +A L+ + LL AQ A + DP+T +RL
Sbjct: 1856 QKLLEAQAATGGIVDLLSRERYSVHKAMERGLIENTSTQRLLNAQKAFTGIEDPVTKKRL 1915
Query: 338 WVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDA 397
V EAV+ G + E L + G DP +IP+ QA+ G++ LA L D
Sbjct: 1916 SVGEAVQKGWMPRESVLPHLQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELAQLLQDE 1975
Query: 398 QLATGGLVCPARRLRLPLEAAL-RC 421
L P + RL + A+ RC
Sbjct: 1976 SSYEKDLTDPISKERLSYKEAMGRC 2000
Score = 53.1 bits (126), Expect = 7e-06
Identities = 83/374 (22%), Positives = 147/374 (39%), Gaps = 65/374 (17%)
Query: 368 DPFSGSQIPLFQAMKKGLVDRPLALRLLD-----AQLATGG-------LVCPARRLRLPL 415
+P +G + ++A K+G++DR L+L + ++ T G L+ + +
Sbjct: 1690 EPETGKDMSPYEAYKRGIIDRGQYLQLQELECDWEEVTTSGPCGEESVLLDRKSGKQYSI 1749
Query: 416 EAALRCGCLDEDTQRQLSQAGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGG 475
EAALRC + ++ + + DG H + LL T P + L+ G
Sbjct: 1750 EAALRCRRISKE------EYHLYKDG-HLPISEFALLVAGETKPSSSLSI----GSIISK 1798
Query: 476 EPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGT 535
P P Q+ S + + S+G L + F
Sbjct: 1799 SPLASP-----APQSTSFFSPSFSLG--------LGDDSF-------------------- 1825
Query: 536 LSVEKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAE-----IIDQDLYERLEHGQ 590
+A T + + + D +T +LL+A+ I+D ER +
Sbjct: 1826 ----PIAGIYDTTTDNKCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHK 1881
Query: 591 ATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAAT 650
A + + S QR L G+ P +++RLS+ EA KG + + L L+ Q T
Sbjct: 1882 AMERGLIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLT 1941
Query: 651 GFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGL 710
G +IDPK +++AL + +I ++ L TDP + +++S +AM +
Sbjct: 1942 GGLIDPKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCR 2001
Query: 711 IVREHGIRLLEAQI 724
G+ LL A +
Sbjct: 2002 KDPLSGLLLLPAAL 2015
Score = 48.1 bits (113), Expect = 2e-04
Identities = 120/566 (21%), Positives = 206/566 (36%), Gaps = 115/566 (20%)
Query: 827 QGQRVSAWELINSEYFSEGRRRQLLRRYRQR---EVTLGQVAKLLEAETQRQADIMLPAL 883
+ +R WE++N E + R + RR R+R TLG+ E+E QR D A
Sbjct: 1533 EDERARVWEMLNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARD---QAD 1589
Query: 884 RSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQR 943
+ + Q L A +++Q Q L + E+ LL + GQ
Sbjct: 1590 QECGRLQQELRA--LERQKQQQTLQ--LQEESKLLSQKTESER--------QKAAQRGQE 1637
Query: 944 LSLYQA--MRQKLLGPRVALALLEAQAATGTIMDPH---SPESLSVDEAVRRGVVGPELY 998
LS +A +R+K + T+ D H S E LS + R + ++
Sbjct: 1638 LSRLEAAILREKD----------QIYEKERTLRDLHAKVSREELSQETQTRETNLSTKI- 1686
Query: 999 GRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQ-----VATGG----- 1048
+P +GK +S ++A K+G+I Q +L E + V T G
Sbjct: 1687 -----------SILEPETGKDMSPYEAYKRGIIDRGQYLQLQELECDWEEVTTSGPCGEE 1735
Query: 1049 --IIDPTSHHHLPMPVAIQRGYVDQE------------METALSSSSETFPTPDGQGRTS 1094
++D S + A++ + +E E AL + ET P+ S
Sbjct: 1736 SVLLDRKSGKQYSIEAALRCRRISKEEYHLYKDGHLPISEFALLVAGETKPSSS----LS 1791
Query: 1095 YAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGTSLWDLLSSCHFT 1154
++ + P P P+S + + P A + D + C
Sbjct: 1792 IGSIISKSPLAS-------PAPQSTSFFSPSFSLGLGDDSFPIAGIYDTTTD--NKCSIK 1842
Query: 1155 EEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDAGII 1214
+ +L+ + T +LL + LL++ R V ++ G+I
Sbjct: 1843 TAVAKNMLDPI-----TGQKLLEAQAATGGIVDLLSRERYSVHKA---------MERGLI 1888
Query: 1215 TQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTG 1274
+ + L ++ + E P K L S+ +AV+ G +P
Sbjct: 1889 ENTSTQRLLNAQKAFTGI-EDPVTKKRL------------------SVGEAVQKGWMPRE 1929
Query: 1275 LGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRA 1334
L+ Q +G L+DP R+ ++ A+ G++ EL++ L DP S+
Sbjct: 1930 SVLPHLQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKE 1989
Query: 1335 SLSLWQAMEKGLVPQNEGLPLLQVQL 1360
LS +AM + GL LL L
Sbjct: 1990 RLSYKEAMGRCRKDPLSGLLLLPAAL 2015
Score = 44.3 bits (103), Expect = 0.003
Identities = 41/182 (22%), Positives = 77/182 (42%), Gaps = 9/182 (4%)
Query: 1835 IEETETQNQ-GIKVAAIRG---EVTAADLFNSR-----VIDQKTLHTLRVGRTGGQALST 1885
I +T T N+ IK A + +T L ++ ++D + V + + L
Sbjct: 1830 IYDTTTDNKCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAMERGLIE 1889
Query: 1886 LECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCT 1945
+ L G+ P T++ +S+ EA +K +P L+ Q TG L+DP
Sbjct: 1890 NTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLTGGLIDPKR 1949
Query: 1946 RQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALR 2005
++ + +A+ G+++EEL + L DP + + + +AM + + L
Sbjct: 1950 TGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCRKDPLSGLL 2009
Query: 2006 LL 2007
LL
Sbjct: 2010 LL 2011
Score = 35.4 bits (80), Expect = 1.5
Identities = 26/97 (26%), Positives = 42/97 (43%)
Query: 1317 LGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQ 1376
LG AG D + S+ A+ K ++ G LL+ Q ATGG+VD +
Sbjct: 1820 LGDDSFPIAGIYDTTTDNKCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSV 1879
Query: 1377 AAACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVT 1413
A GL++ ++Q L K DP + +++
Sbjct: 1880 HKAMERGLIENTSTQRLLNAQKAFTGIEDPVTKKRLS 1916
>gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]
Length = 3062
Score = 92.4 bits (228), Expect = 1e-17
Identities = 111/481 (23%), Positives = 208/481 (43%), Gaps = 81/481 (16%)
Query: 1899 IAGVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVG 1958
IAG +T EV+S+ +A + LI LLE Q L+ P R+ + +A G
Sbjct: 1229 IAGTIDQTTGEVLSVFQAVLRGLIDYDTGIRLLETQLMISGLISPELRKCFDLKDAKSHG 1288
Query: 1959 LVNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVID 2018
L++E++ +L + +A A+ TIP+ A+ + +I ++ A+++LE+ ++TG ++
Sbjct: 1289 LIDEQILCQLKELSKAKE-IISAASPTTIPVLDALAQSMITESMAIKVLEILLSTGSLVI 1347
Query: 2019 PQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDT 2078
P +L L+ A+++ + +++ + ++++M K +DP T EKVS ++ +R QE+T
Sbjct: 1348 PATGEQLTLQKAFQQNLVSSALFSKVLERQNMCKDLIDPCTSEKVSLIDMVQRSTLQENT 1407
Query: 2079 GWVLFPVNKAARDSEHIDDETRRALEAEQVEITVGR-FRGQKPTLWALLNSEYVTEEKKL 2137
G L PV R E ++ + GR + L++ E +
Sbjct: 1408 GMWLLPV---------------RPQEGGRITLKCGRNISILRAAHEGLIDRETMFRLLSA 1452
Query: 2138 QLVR--MYRTHTRRALQTVAQLILELIEKQETSNKHLWFQ----GI-----RRQITASEL 2186
QL+ + +++ + + TV + + E + ++T++ L +Q GI +++T E
Sbjct: 1453 QLLSGGLINSNSGQRM-TVEEAVREGVIDRDTASSILTYQVQTGGIIQSNPAKRLTVDEA 1511
Query: 2187 LSSAIITEEML-------------------QDLETGRSTTQELMEDDRVKRYLEGTSCIA 2227
+ +IT + T S QEL+ ++ + L G IA
Sbjct: 1512 VQCDLITSSSALLVLEAQRGYVGLIWPHSGEIFPTSSSLQQELITNELAYKILNGRQKIA 1571
Query: 2228 GVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVL--------------LEA-------Q 2266
+ +P Q + + A G++ TA +L LEA
Sbjct: 1572 ALYIPESSQ-----VIGLDAAKQLGIIDNNTASILKNITLPDKMPDLGDLEACKNARRWL 1626
Query: 2267 AATGFVIDPVRNLR-----LSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISL 2321
+ F V + R EEPV SE +KL + + Y D TGQ++ L
Sbjct: 1627 SFCKFQPSTVHDYRQEEDVFDGEEPVTTQT--SEETKKLFLSYLMINSYMDANTGQRLLL 1684
Query: 2322 F 2322
+
Sbjct: 1685 Y 1685
Score = 90.1 bits (222), Expect = 5e-17
Identities = 91/382 (23%), Positives = 158/382 (41%), Gaps = 63/382 (16%)
Query: 43 IAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQG 102
IAG + +G+ SV+ A+ +GL+ G LLE Q GL+ + + A G
Sbjct: 1229 IAGTIDQTTGEVLSVFQAVLRGLIDYDTGIRLLETQLMISGLISPELRKCFDLKDAKSHG 1288
Query: 103 LVG----LELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATG 158
L+ +LKE A E + P + + A+ + ++ ++ LE+ L+TG
Sbjct: 1289 LIDEQILCQLKELSKAKEIISAASPTT-----IPVLDALAQSMITESMAIKVLEILLSTG 1343
Query: 159 GLVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERC 218
LV PA G + + A Q L+ + K+ E + DL ++P T E+++ +++R
Sbjct: 1344 SLVIPATGEQLTLQKAFQQNLVSSALFSKVLERQNMCKDL--IDPCTSEKVSLIDMVQRS 1401
Query: 219 VRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVR 278
+G+ LLP+
Sbjct: 1402 TLQENTGMWLLPV----------------------------------------------- 1414
Query: 279 RYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLW 338
R EG G + L G S +AA E L+ T LL AQ + L++ +GQR+
Sbjct: 1415 RPQEG-----GRITLKCGRNISILRAAHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMT 1469
Query: 339 VDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQ 398
V+EAVR G++ + +L + G ++ + +A++ L+ AL +L+AQ
Sbjct: 1470 VEEAVREGVIDRDTASSILTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLVLEAQ 1529
Query: 399 LATGGLVCPARRLRLPLEAALR 420
GL+ P P ++L+
Sbjct: 1530 RGYVGLIWPHSGEIFPTSSSLQ 1551
Score = 89.4 bits (220), Expect = 9e-17
Identities = 95/411 (23%), Positives = 178/411 (43%), Gaps = 31/411 (7%)
Query: 685 ERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAY 744
++ + G D TG+ +S+FQA+ +GLI + GIRLLE Q+ G+I P + A
Sbjct: 1226 DKVIAGTIDQTTGEVLSVFQAVLRGLIDYDTGIRLLETQLMISGLISPELRKCFDLKDAK 1285
Query: 745 RRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSP 804
G D+ + L L K + + L L + + + +L + +
Sbjct: 1286 SHGLIDEQI-LCQLKELSKAKEIISAASPTTIPVLDALAQSMITESMAIKVLEILLSTGS 1344
Query: 805 LVDSAT------QQAFQ-NLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQR 857
LV AT Q+AFQ NL+ S + + ++ +LI+ + +++R +
Sbjct: 1345 LVIPATGEQLTLQKAFQQNLVSSALFSKVLERQNMCKDLIDPCTSEKVSLIDMVQRSTLQ 1404
Query: 858 EVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALL 917
E T LL Q I L R+ +++ + G+ID++ + ++L+ +
Sbjct: 1405 ENT---GMWLLPVRPQEGGRITLKCGRN-ISILRAAHEGLIDRETMFRLLSAQLLS---- 1456
Query: 918 LMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPH 977
GG+ SGQR+++ +A+R+ ++ A ++L Q TG I+ +
Sbjct: 1457 ---------------GGLINSNSGQRMTVEEAVREGVIDRDTASSILTYQVQTGGIIQSN 1501
Query: 978 SPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAA 1037
+ L+VDEAV+ ++ + A+ G P SG+ ++++ LI E A
Sbjct: 1502 PAKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPHSGEIFPTSSSLQQELITNELAY 1561
Query: 1038 RLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSETFPTPD 1088
++L + + P S + + A Q G +D + L + + PD
Sbjct: 1562 KILNGRQKIAALYIPESSQVIGLDAAKQLGIIDNNTASILKNITLPDKMPD 1612
Score = 80.1 bits (196), Expect = 5e-14
Identities = 86/401 (21%), Positives = 170/401 (42%), Gaps = 23/401 (5%)
Query: 1646 ERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGIIDPVHSHRVPVDVAY 1705
++ + G D TG+ +S+FQA+ + LI + GIRLLE Q+ G+I P + A
Sbjct: 1226 DKVIAGTIDQTTGEVLSVFQAVLRGLIDYDTGIRLLETQLMISGLISPELRKCFDLKDAK 1285
Query: 1706 RCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLYLLQIIKKGEN 1765
G DE++ L + S K + + L L + + + +L+I+ +
Sbjct: 1286 SHGLIDEQILCQLKELSK-AKEIISAASPTTIPVLDALAQSMITESMAIKVLEILLSTGS 1344
Query: 1766 YVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLE 1825
V + LQ + +L+SS F++ +R+ + + E
Sbjct: 1345 LVIPATGEQLTLQKAFQQ--------------NLVSSALFSKVLERQNMCKDLIDPCTSE 1390
Query: 1826 KLLEIITTTIEETETQNQGIKVAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALST 1885
K+ +I T +N G+ + +R + I K + + R + L
Sbjct: 1391 KV-SLIDMVQRSTLQENTGMWLLPVRPQEGGR-------ITLKCGRNISILRAAHEGLID 1442
Query: 1886 LECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCT 1945
E + L G+ ++ + M++ EA R+ +I A+ +L Q TG ++
Sbjct: 1443 RETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVIDRDTASSILTYQVQTGGIIQSNP 1502
Query: 1946 RQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALR 2005
++L+VDEAV L+ +L+A+R G P +G+ P ++Q++LI A +
Sbjct: 1503 AKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPHSGEIFPTSSSLQQELITNELAYK 1562
Query: 2006 LLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISD 2046
+L + + P+ + L+ A + G + + +++ +
Sbjct: 1563 ILNGRQKIAALYIPESSQVIGLDAAKQLGIIDNNTASILKN 1603
Score = 80.1 bits (196), Expect = 5e-14
Identities = 85/405 (20%), Positives = 164/405 (40%), Gaps = 36/405 (8%)
Query: 1321 ERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAAC 1380
++ AG D + LS++QA+ +GL+ + G+ LL+ QL G++ P A
Sbjct: 1226 DKVIAGTIDQTTGEVLSVFQAVLRGLIDYDTGIRLLETQLMISGLISPELRKCFDLKDAK 1285
Query: 1381 RLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVL 1440
GL+D Q L + K + S L + + +S
Sbjct: 1286 SHGLIDEQILCQLKELSKAKEIISAASPTTIPVLDALAQSMITES--------------- 1330
Query: 1441 EVDDHTAVALRAMKVPVSTGRF----KGCSVSLWDLLLSEYVGA---DKRRELVALCRSG 1493
+A++ +++ +STG G ++L V + K E +C+
Sbjct: 1331 -------MAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLERQNMCKD- 1382
Query: 1494 RAAALRQVVSAVTALVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTT 1553
+ S +L++ +R LQ V ++ R L + + L
Sbjct: 1383 ---LIDPCTSEKVSLIDMVQRSTLQENTGMWLLPVRPQEGGRITLKCGRNISILRAAH-- 1437
Query: 1554 VKEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGF 1613
+ + + +++ R L G++ + +RM++ EA+R ++ TA +L Q TG
Sbjct: 1438 -EGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVIDRDTASSILTYQVQTGG 1496
Query: 1614 IIDPAENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIV 1673
II ++LTV+EA + + + + +L A+R G P++G+ ++Q++LI
Sbjct: 1497 IIQSNPAKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPHSGEIFPTSSSLQQELIT 1556
Query: 1674 REHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRIL 1718
E ++L + + P S + +D A + G D IL
Sbjct: 1557 NELAYKILNGRQKIAALYIPESSQVIGLDAAKQLGIIDNNTASIL 1601
Score = 79.7 bits (195), Expect = 7e-14
Identities = 84/342 (24%), Positives = 139/342 (40%), Gaps = 54/342 (15%)
Query: 50 ASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELK 109
AS V A+ Q ++ + +LE +TG LV A G+ L + KA QQ LV L
Sbjct: 1311 ASPTTIPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALF 1370
Query: 110 EKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLV 169
K+L + DP EK++L + + + G L V+ GG + G +
Sbjct: 1371 SKVLERQNMCKDLIDPCTSEKVSLIDMVQRSTLQENTGMWLLPVRPQEGGRITLKCGRNI 1430
Query: 170 APEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALL 229
+ A H+GL+DRET +L + +G L +N N+ +R+T
Sbjct: 1431 SILRAAHEGLIDRETMFRLLSAQLLSGGL--INSNSGQRMTV------------------ 1470
Query: 230 PLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAG 289
E+AV REG +D + + Y TG G
Sbjct: 1471 -------------------------EEAV---REG---VIDRDTASSILTYQVQTG---G 1496
Query: 290 VVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVS 349
++ + + +A L+ +AL +LEAQ L+ P +G+ +++ L++
Sbjct: 1497 IIQSNPAKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPHSGEIFPTSSSLQQELIT 1556
Query: 350 PELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLA 391
EL ++L Q + + P S I L A + G++D A
Sbjct: 1557 NELAYKILNGRQKIAALYIPESSQVIGLDAAKQLGIIDNNTA 1598
Score = 78.6 bits (192), Expect = 2e-13
Identities = 90/418 (21%), Positives = 180/418 (43%), Gaps = 49/418 (11%)
Query: 1002 KRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMP 1061
++ + IAG D +G+ +SVFQA+ +GLI ++ RLLE Q+ G+I P +
Sbjct: 1223 EKLDKVIAGTIDQTTGEVLSVFQAVLRGLIDYDTGIRLLETQLMISGLISPELRKCFDLK 1282
Query: 1062 VAIQRGYVDQEMETALSSSSETFPTPDGQGRTSYAQL--LEECPRDETSGLHLLPLPESA 1119
A G +D+++ L S+ T+ L L + E+ + +L + S
Sbjct: 1283 DAKSHGLIDEQILCQLKELSKAKEIISAASPTTIPVLDALAQSMITESMAIKVLEILLST 1342
Query: 1120 -----PALPTEEQVQRSLQAVPGAKDGTSLWDLLSSCHFTEE-QRRGLLEDVQEGRTTVP 1173
PA + +Q++ Q +L+SS F++ +R+ + +D+ + T+
Sbjct: 1343 GSLVIPATGEQLTLQKAFQQ-----------NLVSSALFSKVLERQNMCKDLIDPCTSEK 1391
Query: 1174 -QLLASVQR---------WVQETKLLAQARVMVPGPRGEVPAVWLLDAGIITQETLEALA 1223
L+ VQR W+ + R+ + R + + G+I +ET+ L
Sbjct: 1392 VSLIDMVQRSTLQENTGMWLLPVRPQEGGRITLKCGRN-ISILRAAHEGLIDRETMFRLL 1450
Query: 1224 QGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQ 1283
AQ+ G++ SG + ++ +AVR+G++ +L Q
Sbjct: 1451 S-----AQLLS--------------GGLINSNSGQRMTVEEAVREGVIDRDTASSILTYQ 1491
Query: 1284 VASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAME 1343
V +G ++ +RL+V++AV+ L+ + + +A+R G P+S +++
Sbjct: 1492 VQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPHSGEIFPTSSSLQ 1551
Query: 1344 KGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNK 1401
+ L+ +L + + P + AA +LG++D T+ +L + +K
Sbjct: 1552 QELITNELAYKILNGRQKIAALYIPESSQVIGLDAAKQLGIIDNNTASILKNITLPDK 1609
Score = 77.0 bits (188), Expect = 4e-13
Identities = 88/414 (21%), Positives = 162/414 (39%), Gaps = 43/414 (10%)
Query: 1970 KAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLET 2029
K ++ G D TG+ + +FQA+ + LI+ +RLLE Q+ G+I P+ L+
Sbjct: 1224 KLDKVIAGTIDQTTGEVLSVFQAVLRGLIDYDTGIRLLETQLMISGLISPELRKCFDLKD 1283
Query: 2030 AYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWVLFPVNKAA 2089
A G + + I + +E +E+ P PV A
Sbjct: 1284 AKSHGLIDEQILCQL---------------KELSKAKEIISAASP------TTIPVLDAL 1322
Query: 2090 RDSEHIDDETRRALEAEQVEITVGRF----RGQKPTLWALLNSEYVTE---EKKLQLVRM 2142
S + + LE + ++ G G++ TL V+ K L+ M
Sbjct: 1323 AQSMITESMAIKVLE---ILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLERQNM 1379
Query: 2143 YRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLET 2202
+ LI + N +W +R Q IT + +++
Sbjct: 1380 CKDLIDPCTSEKVSLIDMVQRSTLQENTGMWLLPVRPQ-------EGGRITLKCGRNISI 1432
Query: 2203 GRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVL 2262
R+ + L++ + + R L G++ Q +M++ +A+ +GV+ TA +
Sbjct: 1433 LRAAHEGLIDRETMFRLLSAQLLSGGLINSNSGQ-----RMTVEEAVREGVIDRDTASSI 1487
Query: 2263 LEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEIQEKLLSAERAVTGYTDPYTGQQISLF 2322
L Q TG +I RL+V+E V ++ S +L A+R G P++G+
Sbjct: 1488 LTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPHSGEIFPTS 1547
Query: 2323 QAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVL 2376
++Q++LI E ++L + + P S + +D A + G D +L
Sbjct: 1548 SSLQQELITNELAYKILNGRQKIAALYIPESSQVIGLDAAKQLGIIDNNTASIL 1601
Score = 76.3 bits (186), Expect = 7e-13
Identities = 79/323 (24%), Positives = 128/323 (39%), Gaps = 58/323 (17%)
Query: 106 LELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQ 165
++++EKL ++ G D GE L++FQA+ + ++D G LE QL GL+ P
Sbjct: 1219 VKVEEKL---DKVIAGTIDQTTGEVLSVFQAVLRGLIDYDTGIRLLETQLMISGLISPEL 1275
Query: 166 GVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLNPNTLERLTYHQLLERCVRAPGSG 225
+ A GL+D + +L EL
Sbjct: 1276 RKCFDLKDAKSHGLIDEQILCQLKELSKAKE----------------------------- 1306
Query: 226 LALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTG 285
+SAA + +LD A + E S +V L TG
Sbjct: 1307 ---------------IISAASPTTIPVLDALAQSMITE--------SMAIKVLEILLSTG 1343
Query: 286 SVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRA 345
S+ V+ G + + +A ++L+ +LE Q L+DP T +++ + + V+
Sbjct: 1344 SL---VIPATGEQLTLQKAFQQNLVSSALFSKVLERQNMCKDLIDPCTSEKVSLIDMVQR 1400
Query: 346 GLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLV 405
+ LL G G I + +A +GL+DR RLL AQL +GGL+
Sbjct: 1401 STLQENTGMWLLPVRPQEGGRITLKCGRNISILRAAHEGLIDRETMFRLLSAQLLSGGLI 1460
Query: 406 CPARRLRLPLEAALRCGCLDEDT 428
R+ +E A+R G +D DT
Sbjct: 1461 NSNSGQRMTVEEAVREGVIDRDT 1483
Score = 75.9 bits (185), Expect = 1e-12
Identities = 87/436 (19%), Positives = 174/436 (39%), Gaps = 50/436 (11%)
Query: 1542 KTLDE-----LSQGTTTVKEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHIL 1596
KTL E S+ ++E VK + IAG + Q T E +S+ +A+ R ++
Sbjct: 1193 KTLQESYNLLFSESLKQLQESQTSGDVKVEEKLDKVIAGTIDQTTGEVLSVFQAVLRGLI 1252
Query: 1597 RPGTALVLLEAQAATGFIIDPAENRKLTVEEAFKAGMFGKETYVKL--LSAERAVTGYTD 1654
T + LLE Q +I P + +++A G+ ++ +L LS + +
Sbjct: 1253 DYDTGIRLLETQLMISGLISPELRKCFDLKDAKSHGLIDEQILCQLKELSKAKEIISAAS 1312
Query: 1655 PYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEM 1714
P T I + A+ + +I I++LE ++TG ++ P ++ + A++ +
Sbjct: 1313 PTT---IPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSAL 1369
Query: 1715 NRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLYLLQI---------IKKGEN 1765
+ + + K DP T E ++ + +++R TG++LL + +K G N
Sbjct: 1370 FSKVLERQNMCKDLIDPCTSEKVSLIDMVQRSTLQENTGMWLLPVRPQEGGRITLKCGRN 1429
Query: 1766 YVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLE 1825
+ A ++ T + LLS + + + E + G ++
Sbjct: 1430 ISILRAAHEGLIDRETMFRLLSA---------QLLSGGLINSNSGQRMTVEEAVREGVID 1480
Query: 1826 KLLEIITTTIEETETQNQGIKVAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALST 1885
+ ++I + Q GI + +T + +I T AL
Sbjct: 1481 R---DTASSILTYQVQTGGIIQSNPAKRLTVDEAVQCDLI------------TSSSALLV 1525
Query: 1886 LECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCT 1945
LE + Y+ G+ P + E+ + ++ELI A +L + L P +
Sbjct: 1526 LEAQRGYV-------GLIWPHSGEIFPTSSSLQQELITNELAYKILNGRQKIAALYIPES 1578
Query: 1946 RQKLSVDEAVDVGLVN 1961
Q + +D A +G+++
Sbjct: 1579 SQVIGLDAAKQLGIID 1594
Score = 72.0 bits (175), Expect = 1e-11
Identities = 55/222 (24%), Positives = 105/222 (47%), Gaps = 10/222 (4%)
Query: 4871 AQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTAL 4930
++ K LQE VK + IAG + DQ E +S++QA+ +G++ T +
Sbjct: 1204 SESLKQLQESQTSGDVKVEEKLDKVIAGTI----DQT-TGEVLSVFQAVLRGLIDYDTGI 1258
Query: 4931 VLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEI--QEKLLSAERAVTGYTDPYTGQQ 4988
LLE Q +I P +++A + G++ +I Q K LS + + P T
Sbjct: 1259 RLLETQLMISGLISPELRKCFDLKDAKSHGLIDEQILCQLKELSKAKEIISAASPTT--- 1315
Query: 4989 ISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 5048
I + A+ + +I I++LE ++TG ++ P ++ + A+++ + + +
Sbjct: 1316 IPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLE 1375
Query: 5049 PSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSLQ 5090
+ K DP T E ++ + ++QR+TL TG+ L + Q
Sbjct: 1376 RQNMCKDLIDPCTSEKVSLIDMVQRSTLQENTGMWLLPVRPQ 1417
Score = 72.0 bits (175), Expect = 1e-11
Identities = 95/412 (23%), Positives = 165/412 (40%), Gaps = 50/412 (12%)
Query: 360 EQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAAL 419
++ + G D +G + +FQA+ +GL+D +RLL+ QL GL+ P R L+ A
Sbjct: 1226 DKVIAGTIDQTTGEVLSVFQAVLRGLIDYDTGIRLLETQLMISGLISPELRKCFDLKDAK 1285
Query: 420 RCGCLDEDTQ---RQLSQAGSF-SDGTHGGLRYEQLLALCVTDPETGLAFLP--LSGG-- 471
G +DE ++LS+A S + + LA + + L LS G
Sbjct: 1286 SHGLIDEQILCQLKELSKAKEIISAASPTTIPVLDALAQSMITESMAIKVLEILLSTGSL 1345
Query: 472 --PRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAIS---SEQRAM 526
P GE ++ + +Q L ++ V + + L + SE +S QR+
Sbjct: 1346 VIPATGEQLT---LQKAFQQNLVSSALFSKVLERQNMCKDLIDPCTSEKVSLIDMVQRST 1402
Query: 527 LAQQYQEGTLSVE-KLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYER 585
L + L V + ++ + + R GL D T LL A+++
Sbjct: 1403 LQENTGMWLLPVRPQEGGRITLKCGRNISILRAAHEGLIDRETMFRLLSAQLLS------ 1456
Query: 586 LEHGQATAKDVGSLASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLE 645
GL+ S +R+++ EA +G++ TA +L
Sbjct: 1457 ---------------------------GGLINSNSGQRMTVEEAVREGVIDRDTASSILT 1489
Query: 646 AQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQA 705
Q TG II K +V+EA++ +I +L A+R G P++G+ +
Sbjct: 1490 YQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPHSGEIFPTSSS 1549
Query: 706 MQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLIL 757
+Q+ LI E ++L + + P S + +D A + G D IL
Sbjct: 1550 LQQELITNELAYKILNGRQKIAALYIPESSQVIGLDAAKQLGIIDNNTASIL 1601
Score = 68.9 bits (167), Expect = 1e-10
Identities = 77/339 (22%), Positives = 146/339 (43%), Gaps = 43/339 (12%)
Query: 3803 AQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTAL 3862
++ K LQE VK + IAG + DQ E +S++QA+ +G++ T +
Sbjct: 1204 SESLKQLQESQTSGDVKVEEKLDKVIAGTI----DQT-TGEVLSVFQAVLRGLIDYDTGI 1258
Query: 3863 VLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEI--QEKLLSAERAVTGYTDPYTGQQ 3920
LLE Q +I P +++A + G++ +I Q K LS + + P T
Sbjct: 1259 RLLETQLMISGLISPELRKCFDLKDAKSHGLIDEQILCQLKELSKAKEIISAASPTT--- 1315
Query: 3921 ISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 3980
I + A+ + +I I++LE ++TG ++ P ++ + A+++ + + +
Sbjct: 1316 IPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLE 1375
Query: 3981 PSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL-----------AGRG----SA 4025
+ K DP T E ++ + +++R +TG+++L + GR A
Sbjct: 1376 RQNMCKDLIDPCTSEKVSLIDMVQRSTLQENTGMWLLPVRPQEGGRITLKCGRNISILRA 1435
Query: 4026 VHQ--LSEELRCALRDARVTPGS--GALQGQSVSVWELLFYREVSEDRRQDLLSRYRAST 4081
H+ + E L A++ G + GQ ++V E + + D +L+ Y+ T
Sbjct: 1436 AHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVIDRDTASSILT-YQVQT 1494
Query: 4082 -----------LTVEELGATLTSLLAQAQAQARAEAEAG 4109
LTV+E A L+ + A EA+ G
Sbjct: 1495 GGIIQSNPAKRLTVDE--AVQCDLITSSSALLVLEAQRG 1531
Score = 68.2 bits (165), Expect = 2e-10
Identities = 77/339 (22%), Positives = 146/339 (43%), Gaps = 43/339 (12%)
Query: 2735 AQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTAL 2794
++ K LQE VK + IAG + DQ E +S++QA+ +G++ T +
Sbjct: 1204 SESLKQLQESQTSGDVKVEEKLDKVIAGTI----DQT-TGEVLSVFQAVLRGLIDYDTGI 1258
Query: 2795 VLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEI--QEKLLSAERAVTGYTDPYTGQQ 2852
LLE Q +I P +++A + G++ +I Q K LS + + P T
Sbjct: 1259 RLLETQLMISGLISPELRKCFDLKDAKSHGLIDEQILCQLKELSKAKEIISAASPTT--- 1315
Query: 2853 ISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 2912
I + A+ + +I I++LE ++TG ++ P ++ + A+++ + + +
Sbjct: 1316 IPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLE 1375
Query: 2913 PSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL-----------AGRG----SA 2957
+ K DP T E ++ + +++R +TG+++L + GR A
Sbjct: 1376 RQNMCKDLIDPCTSEKVSLIDMVQRSTLQENTGMWLLPVRPQEGGRITLKCGRNISILRA 1435
Query: 2958 VHQ--LSEELRCALRDARVTPGS--GALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGT 3013
H+ + E L A++ G + GQ ++V E + + D +L+ Y+ T
Sbjct: 1436 AHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVIDRDTASSILT-YQVQT 1494
Query: 3014 -----------LTVEELGATLTSLLAQAQAQARAEAEAG 3041
LTV+E A L+ + A EA+ G
Sbjct: 1495 GGIIQSNPAKRLTVDE--AVQCDLITSSSALLVLEAQRG 1531
Score = 68.2 bits (165), Expect = 2e-10
Identities = 77/339 (22%), Positives = 146/339 (43%), Gaps = 43/339 (12%)
Query: 3269 AQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTAL 3328
++ K LQE VK + IAG + DQ E +S++QA+ +G++ T +
Sbjct: 1204 SESLKQLQESQTSGDVKVEEKLDKVIAGTI----DQT-TGEVLSVFQAVLRGLIDYDTGI 1258
Query: 3329 VLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEI--QEKLLSAERAVTGYTDPYTGQQ 3386
LLE Q +I P +++A + G++ +I Q K LS + + P T
Sbjct: 1259 RLLETQLMISGLISPELRKCFDLKDAKSHGLIDEQILCQLKELSKAKEIISAASPTT--- 1315
Query: 3387 ISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 3446
I + A+ + +I I++LE ++TG ++ P ++ + A+++ + + +
Sbjct: 1316 IPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLE 1375
Query: 3447 PSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL-----------AGRG----SA 3491
+ K DP T E ++ + +++R +TG+++L + GR A
Sbjct: 1376 RQNMCKDLIDPCTSEKVSLIDMVQRSTLQENTGMWLLPVRPQEGGRITLKCGRNISILRA 1435
Query: 3492 VHQ--LSEELRCALRDARVTPGS--GALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGT 3547
H+ + E L A++ G + GQ ++V E + + D +L+ Y+ T
Sbjct: 1436 AHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVIDRDTASSILT-YQVQT 1494
Query: 3548 -----------LTVEELGATLTSLLAQAQAQARAEAEAG 3575
LTV+E A L+ + A EA+ G
Sbjct: 1495 GGIIQSNPAKRLTVDE--AVQCDLITSSSALLVLEAQRG 1531
Score = 68.2 bits (165), Expect = 2e-10
Identities = 77/339 (22%), Positives = 146/339 (43%), Gaps = 43/339 (12%)
Query: 4337 AQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTAL 4396
++ K LQE VK + IAG + DQ E +S++QA+ +G++ T +
Sbjct: 1204 SESLKQLQESQTSGDVKVEEKLDKVIAGTI----DQT-TGEVLSVFQAVLRGLIDYDTGI 1258
Query: 4397 VLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEI--QEKLLSAERAVTGYTDPYTGQQ 4454
LLE Q +I P +++A + G++ +I Q K LS + + P T
Sbjct: 1259 RLLETQLMISGLISPELRKCFDLKDAKSHGLIDEQILCQLKELSKAKEIISAASPTT--- 1315
Query: 4455 ISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLAD 4514
I + A+ + +I I++LE ++TG ++ P ++ + A+++ + + +
Sbjct: 1316 IPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLE 1375
Query: 4515 PSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQL-----------AGRG----SA 4559
+ K DP T E ++ + +++R +TG+++L + GR A
Sbjct: 1376 RQNMCKDLIDPCTSEKVSLIDMVQRSTLQENTGMWLLPVRPQEGGRITLKCGRNISILRA 1435
Query: 4560 VHQ--LSEELRCALRDARVTPGS--GALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGT 4615
H+ + E L A++ G + GQ ++V E + + D +L+ Y+ T
Sbjct: 1436 AHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVIDRDTASSILT-YQVQT 1494
Query: 4616 -----------LTVEELGATLTSLLAQAQAQARAEAEAG 4643
LTV+E A L+ + A EA+ G
Sbjct: 1495 GGIIQSNPAKRLTVDE--AVQCDLITSSSALLVLEAQRG 1531
Score = 67.8 bits (164), Expect = 3e-10
Identities = 47/187 (25%), Positives = 88/187 (47%), Gaps = 1/187 (0%)
Query: 1248 VAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVG 1307
+AG + Q +G S+ QAV GL+ G RLLE Q+ L+ P + ++DA G
Sbjct: 1229 IAGTIDQTTGEVLSVFQAVLRGLIDYDTGIRLLETQLMISGLISPELRKCFDLKDAKSHG 1288
Query: 1308 LVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVD 1367
L+ ++ QL + +A S ++ + A+ + ++ ++ + +L++ L+TG +V
Sbjct: 1289 LIDEQILCQLKELSKAKE-IISAASPTTIPVLDALAQSMITESMAIKVLEILLSTGSLVI 1347
Query: 1368 PVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSET 1427
P G L A + L+ + + K DP ++V+ + +R T
Sbjct: 1348 PATGEQLTLQKAFQQNLVSSALFSKVLERQNMCKDLIDPCTSEKVSLIDMVQRSTLQENT 1407
Query: 1428 GLLLLPL 1434
G+ LLP+
Sbjct: 1408 GMWLLPV 1414
Score = 65.9 bits (159), Expect = 1e-09
Identities = 106/515 (20%), Positives = 199/515 (38%), Gaps = 65/515 (12%)
Query: 480 PPFIKYS-TRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSV 538
PPF K + + +ST +S + + L+ + ++ E+R L +Q + S
Sbjct: 1143 PPFSKQKISSEEISTKKEQLSEAL---QTIQLFLAKHGDKMTDEERNELEKQVKTLQESY 1199
Query: 539 EKLAAELSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGS 598
L +E L+++ + V D V G IDQ E L QA + +
Sbjct: 1200 NLLFSESLKQLQESQTSGDVKVEEKLDKVIAGT------IDQTTGEVLSVFQAVLRGLID 1253
Query: 599 LASAQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKA 658
+ R L+ I+GL+ P ++ + +A+ GL+ L E A II +
Sbjct: 1254 YDTGIRLLETQLMISGLISPELRKCFDLKDAKSHGLIDEQILCQLKELSKAKE-IISAAS 1312
Query: 659 NKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIR 718
V +AL ++I + K+L + P TG+Q++L +A Q+ L+ +
Sbjct: 1313 PTTIPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSK 1372
Query: 719 LLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTY 778
+LE Q +IDP S +V + +R + + LL G N++
Sbjct: 1373 VLERQNMCKDLIDPCTSEKVSLIDMVQRSTLQENTGMWLLPVRPQEGGRITLKCGRNISI 1432
Query: 779 LQLLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELIN 838
L+ + D ET LL L++S + GQR++ E +
Sbjct: 1433 LRAAHEGLIDRETMFRLLSAQLLSGGLINSNS-----------------GQRMTVEEAV- 1474
Query: 839 SEYFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGII 898
R+ + + +L + Q I+ R+TV + ++ +I
Sbjct: 1475 ----------------REGVIDRDTASSILTYQVQ-TGGIIQSNPAKRLTVDEAVQCDLI 1517
Query: 899 DQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPR 958
S ALL+++ R Y+ G+ SG+ +++Q+L+
Sbjct: 1518 ------------TSSSALLVLEAQRGYV-------GLIWPHSGEIFPTSSSLQQELITNE 1558
Query: 959 VALALLEAQAATGTIMDPHSPESLSVDEAVRRGVV 993
+A +L + + P S + + +D A + G++
Sbjct: 1559 LAYKILNGRQKIAALYIPESSQVIGLDAAKQLGII 1593
Score = 65.5 bits (158), Expect = 1e-09
Identities = 84/423 (19%), Positives = 179/423 (42%), Gaps = 64/423 (15%)
Query: 2117 GQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQG 2176
G+ P ++SE ++ +K+ ALQT+ + + +K ++
Sbjct: 1141 GKPPFSKQKISSEEISTKKE---------QLSEALQTIQLFLAKHGDKMTDEERN----E 1187
Query: 2177 IRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQ 2236
+ +Q+ + + + +E + Q E+ T+ ++ ++++ + + GT DQ
Sbjct: 1188 LEKQVKTLQESYNLLFSESLKQLQES--QTSGDVKVEEKLDKVIAGTI----------DQ 1235
Query: 2237 PGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEPVPAGVVGSEI 2296
E +S++QA+ +G++ T + LLE Q +I P +++ G++ +I
Sbjct: 1236 T-TGEVLSVFQAVLRGLIDYDTGIRLLETQLMISGLISPELRKCFDLKDAKSHGLIDEQI 1294
Query: 2297 --QEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHS 2354
Q K LS + + P T I + A+ + +I I++LE ++TG ++ P
Sbjct: 1295 LCQLKELSKAKEIISAASPTT---IPVLDALAQSMITESMAIKVLEILLSTGSLVIPATG 1351
Query: 2355 HRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYM 2414
++ + A+++ + + + + K DP T E ++ + +++R +TG+++
Sbjct: 1352 EQLTLQKAFQQNLVSSALFSKVLERQNMCKDLIDPCTSEKVSLIDMVQRSTLQENTGMWL 1411
Query: 2415 LQL-----------AGRG----SAVHQ--LSEELRCALRDARVTPGS--GALQGQSVSVW 2455
L + GR A H+ + E L A++ G + GQ ++V
Sbjct: 1412 LPVRPQEGGRITLKCGRNISILRAAHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVE 1471
Query: 2456 ELLFYREVSEDRRQDLLSRYRAGT-----------LTVEELGATLTSLLAQAQAQARAEA 2504
E + + D +L+ Y+ T LTV+E A L+ + A EA
Sbjct: 1472 EAVREGVIDRDTASSILT-YQVQTGGIIQSNPAKRLTVDE--AVQCDLITSSSALLVLEA 1528
Query: 2505 EAG 2507
+ G
Sbjct: 1529 QRG 1531
Score = 59.7 bits (143), Expect = 7e-08
Identities = 51/253 (20%), Positives = 114/253 (45%), Gaps = 13/253 (5%)
Query: 1825 EKLLEIITTTIEETETQNQGIKVAAIRGEV---TAADLFNSRVI-------DQKTLHTLR 1874
EKL ++I TI++T + + A +RG + T L ++++ + + L+
Sbjct: 1223 EKLDKVIAGTIDQTTGEVLSVFQAVLRGLIDYDTGIRLLETQLMISGLISPELRKCFDLK 1282
Query: 1875 VGRTGGQALSTLECVKPYLEGSDCIAGVTVPSTREVMSLHEASRKELIPAAFATWLLEAQ 1934
++ G + C L + I P+T V+ +A + +I + A +LE
Sbjct: 1283 DAKSHGLIDEQILCQLKELSKAKEIISAASPTTIPVL---DALAQSMITESMAIKVLEIL 1339
Query: 1935 AATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTIPLFQAMQ 1994
+TG L+ P T ++L++ +A LV+ L ++L+ + DP T + + L +Q
Sbjct: 1340 LSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLERQNMCKDLIDPCTSEKVSLIDMVQ 1399
Query: 1995 KQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRF 2054
+ +++ + LL V+ GG I + + + A G + ++ + + +
Sbjct: 1400 RSTLQENTGMWLLPVRPQEGGRITLKCGRNISILRAAHEGLIDRETMFRLLSAQLLSGGL 1459
Query: 2055 VDPNTQEKVSYRE 2067
++ N+ ++++ E
Sbjct: 1460 INSNSGQRMTVEE 1472
Score = 58.5 bits (140), Expect = 2e-07
Identities = 70/307 (22%), Positives = 129/307 (42%), Gaps = 24/307 (7%)
Query: 4791 VSVWDVLFSSYLSEARRDELLA-QHAAGALGLPDLVAVLTRVIEETEERLSKVSF-RGLR 4848
+ V D L S ++E+ ++L + G+L +P LT + +S F + L
Sbjct: 1316 IPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLE 1375
Query: 4849 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 4908
RQ +L +L D+ Q + TLQE T M L+P + Q G
Sbjct: 1376 RQNMCKDLIDPCTSEKVSLIDMVQRS-TLQENTGM---------------WLLPVRPQEG 1419
Query: 4909 RQ------EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVV 4962
+ +SI +A +G++ T LL AQ +G +I+ R++VEEAV GV+
Sbjct: 1420 GRITLKCGRNISILRAAHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVI 1479
Query: 4963 GGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPV 5022
+ +L+ + G +++++ +A+Q DLI + +LEAQ G+I P
Sbjct: 1480 DRDTASSILTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPH 1539
Query: 5023 HSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGL 5082
P + ++ E+ + + + P + + + Q +D T
Sbjct: 1540 SGEIFPTSSSLQQELITNELAYKILNGRQKIAALYIPESSQVIGLDAAKQLGIIDNNTAS 1599
Query: 5083 LFLSLSL 5089
+ +++L
Sbjct: 1600 ILKNITL 1606
Score = 57.0 bits (136), Expect = 5e-07
Identities = 35/136 (25%), Positives = 66/136 (48%)
Query: 2775 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 2834
++M++ +A+ +GV+ TA +L Q TG +I RL+V+EAV ++ +
Sbjct: 1466 QRMTVEEAVREGVIDRDTASSILTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLV 1525
Query: 2835 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 2894
L A+R G P++G+ ++Q++LI E ++L + + P S + +D
Sbjct: 1526 LEAQRGYVGLIWPHSGEIFPTSSSLQQELITNELAYKILNGRQKIAALYIPESSQVIGLD 1585
Query: 2895 VAYRRGYFDEEMNRVL 2910
A + G D +L
Sbjct: 1586 AAKQLGIIDNNTASIL 1601
Score = 57.0 bits (136), Expect = 5e-07
Identities = 35/136 (25%), Positives = 66/136 (48%)
Query: 3309 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 3368
++M++ +A+ +GV+ TA +L Q TG +I RL+V+EAV ++ +
Sbjct: 1466 QRMTVEEAVREGVIDRDTASSILTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLV 1525
Query: 3369 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 3428
L A+R G P++G+ ++Q++LI E ++L + + P S + +D
Sbjct: 1526 LEAQRGYVGLIWPHSGEIFPTSSSLQQELITNELAYKILNGRQKIAALYIPESSQVIGLD 1585
Query: 3429 VAYRRGYFDEEMNRVL 3444
A + G D +L
Sbjct: 1586 AAKQLGIIDNNTASIL 1601
Score = 57.0 bits (136), Expect = 5e-07
Identities = 35/136 (25%), Positives = 66/136 (48%)
Query: 3843 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 3902
++M++ +A+ +GV+ TA +L Q TG +I RL+V+EAV ++ +
Sbjct: 1466 QRMTVEEAVREGVIDRDTASSILTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLV 1525
Query: 3903 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 3962
L A+R G P++G+ ++Q++LI E ++L + + P S + +D
Sbjct: 1526 LEAQRGYVGLIWPHSGEIFPTSSSLQQELITNELAYKILNGRQKIAALYIPESSQVIGLD 1585
Query: 3963 VAYRRGYFDEEMNRVL 3978
A + G D +L
Sbjct: 1586 AAKQLGIIDNNTASIL 1601
Score = 57.0 bits (136), Expect = 5e-07
Identities = 35/136 (25%), Positives = 66/136 (48%)
Query: 4377 EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKL 4436
++M++ +A+ +GV+ TA +L Q TG +I RL+V+EAV ++ +
Sbjct: 1466 QRMTVEEAVREGVIDRDTASSILTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLV 1525
Query: 4437 LSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVD 4496
L A+R G P++G+ ++Q++LI E ++L + + P S + +D
Sbjct: 1526 LEAQRGYVGLIWPHSGEIFPTSSSLQQELITNELAYKILNGRQKIAALYIPESSQVIGLD 1585
Query: 4497 VAYRRGYFDEEMNRVL 4512
A + G D +L
Sbjct: 1586 AAKQLGIIDNNTASIL 1601
Score = 56.2 bits (134), Expect = 8e-07
Identities = 65/260 (25%), Positives = 113/260 (43%), Gaps = 24/260 (9%)
Query: 2655 VSVWDVLFSSYLSEARRDELLA-QHAAGALGLPDLVAVLTRVIEETEERLSKVSF-RGLR 2712
+ V D L S ++E+ ++L + G+L +P LT + +S F + L
Sbjct: 1316 IPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLE 1375
Query: 2713 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 2772
RQ +L +L D+ Q + TLQE T M L+P + Q G
Sbjct: 1376 RQNMCKDLIDPCTSEKVSLIDMVQRS-TLQENTGM---------------WLLPVRPQEG 1419
Query: 2773 RQ------EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVV 2826
+ +SI +A +G++ T LL AQ +G +I+ R++VEEAV GV+
Sbjct: 1420 GRITLKCGRNISILRAAHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVI 1479
Query: 2827 GGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPV 2886
+ +L+ + G +++++ +A+Q DLI + +LEAQ G+I P
Sbjct: 1480 DRDTASSILTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPH 1539
Query: 2887 HSHRVPVDVAYRRGYFDEEM 2906
P + ++ E+
Sbjct: 1540 SGEIFPTSSSLQQELITNEL 1559
Score = 56.2 bits (134), Expect = 8e-07
Identities = 65/260 (25%), Positives = 113/260 (43%), Gaps = 24/260 (9%)
Query: 3189 VSVWDVLFSSYLSEARRDELLA-QHAAGALGLPDLVAVLTRVIEETEERLSKVSF-RGLR 3246
+ V D L S ++E+ ++L + G+L +P LT + +S F + L
Sbjct: 1316 IPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLE 1375
Query: 3247 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 3306
RQ +L +L D+ Q + TLQE T M L+P + Q G
Sbjct: 1376 RQNMCKDLIDPCTSEKVSLIDMVQRS-TLQENTGM---------------WLLPVRPQEG 1419
Query: 3307 RQ------EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVV 3360
+ +SI +A +G++ T LL AQ +G +I+ R++VEEAV GV+
Sbjct: 1420 GRITLKCGRNISILRAAHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVI 1479
Query: 3361 GGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPV 3420
+ +L+ + G +++++ +A+Q DLI + +LEAQ G+I P
Sbjct: 1480 DRDTASSILTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPH 1539
Query: 3421 HSHRVPVDVAYRRGYFDEEM 3440
P + ++ E+
Sbjct: 1540 SGEIFPTSSSLQQELITNEL 1559
Score = 56.2 bits (134), Expect = 8e-07
Identities = 65/260 (25%), Positives = 113/260 (43%), Gaps = 24/260 (9%)
Query: 3723 VSVWDVLFSSYLSEARRDELLA-QHAAGALGLPDLVAVLTRVIEETEERLSKVSF-RGLR 3780
+ V D L S ++E+ ++L + G+L +P LT + +S F + L
Sbjct: 1316 IPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLE 1375
Query: 3781 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 3840
RQ +L +L D+ Q + TLQE T M L+P + Q G
Sbjct: 1376 RQNMCKDLIDPCTSEKVSLIDMVQRS-TLQENTGM---------------WLLPVRPQEG 1419
Query: 3841 RQ------EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVV 3894
+ +SI +A +G++ T LL AQ +G +I+ R++VEEAV GV+
Sbjct: 1420 GRITLKCGRNISILRAAHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVI 1479
Query: 3895 GGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPV 3954
+ +L+ + G +++++ +A+Q DLI + +LEAQ G+I P
Sbjct: 1480 DRDTASSILTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPH 1539
Query: 3955 HSHRVPVDVAYRRGYFDEEM 3974
P + ++ E+
Sbjct: 1540 SGEIFPTSSSLQQELITNEL 1559
Score = 56.2 bits (134), Expect = 8e-07
Identities = 65/260 (25%), Positives = 113/260 (43%), Gaps = 24/260 (9%)
Query: 4257 VSVWDVLFSSYLSEARRDELLA-QHAAGALGLPDLVAVLTRVIEETEERLSKVSF-RGLR 4314
+ V D L S ++E+ ++L + G+L +P LT + +S F + L
Sbjct: 1316 IPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLE 1375
Query: 4315 RQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPG 4374
RQ +L +L D+ Q + TLQE T M L+P + Q G
Sbjct: 1376 RQNMCKDLIDPCTSEKVSLIDMVQRS-TLQENTGM---------------WLLPVRPQEG 1419
Query: 4375 RQ------EKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVV 4428
+ +SI +A +G++ T LL AQ +G +I+ R++VEEAV GV+
Sbjct: 1420 GRITLKCGRNISILRAAHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVI 1479
Query: 4429 GGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPV 4488
+ +L+ + G +++++ +A+Q DLI + +LEAQ G+I P
Sbjct: 1480 DRDTASSILTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPH 1539
Query: 4489 HSHRVPVDVAYRRGYFDEEM 4508
P + ++ E+
Sbjct: 1540 SGEIFPTSSSLQQELITNEL 1559
Score = 55.1 bits (131), Expect = 2e-06
Identities = 47/222 (21%), Positives = 96/222 (43%), Gaps = 8/222 (3%)
Query: 8 PLPVPGTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAAMEQGLLP 67
P +P ++ Q+ + +MA + S + + A+G+ ++ A +Q L+
Sbjct: 1313 PTTIPVLDALAQSMITESMAIKV------LEILLSTGSLVIPATGEQLTLQKAFQQNLVS 1366
Query: 68 AGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYG 127
+ L +LE Q L+D + + + +Q+ + LL G
Sbjct: 1367 SALFSKVLERQNMCKDLIDPCTSEKVSLIDMVQRSTLQENTGMWLLPVRPQEGGRITLKC 1426
Query: 128 GEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLLDRETWHK 187
G +++ +A + ++DR L QL +GGL++ G + E A +G++DR+T
Sbjct: 1427 GRNISILRAAHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVIDRDTASS 1486
Query: 188 LSELEPGTGDLRFLNPNTLERLTYHQLLERCVRAPGSGLALL 229
+ + TG + + N +RLT + ++ + S L +L
Sbjct: 1487 ILTYQVQTGGI--IQSNPAKRLTVDEAVQCDLITSSSALLVL 1526
Score = 55.1 bits (131), Expect = 2e-06
Identities = 48/220 (21%), Positives = 97/220 (44%), Gaps = 10/220 (4%)
Query: 1215 TQETLEALAQGTQSPAQVAEQPAVKAC--LWGTGCVAGVLLQPSGAKASIAQAVRDGLLP 1272
T L+ALAQ + + E A+K L TG +++ +G + ++ +A + L+
Sbjct: 1315 TIPVLDALAQ-----SMITESMAIKVLEILLSTG---SLVIPATGEQLTLQKAFQQNLVS 1366
Query: 1273 TGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYS 1332
+ L ++LE Q L+DP ++++S+ D V+ + L G
Sbjct: 1367 SALFSKVLERQNMCKDLIDPCTSEKVSLIDMVQRSTLQENTGMWLLPVRPQEGGRITLKC 1426
Query: 1333 RASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQV 1392
++S+ +A +GL+ + LL QL +GG+++ G + A R G++D T+
Sbjct: 1427 GRNISILRAAHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVIDRDTASS 1486
Query: 1393 LTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLL 1432
+ + ++T + + + S + LL+L
Sbjct: 1487 ILTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLVL 1526
Score = 51.2 bits (121), Expect = 3e-05
Identities = 38/159 (23%), Positives = 67/159 (42%), Gaps = 5/159 (3%)
Query: 45 GVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGLV 104
G+ SGQ +V A+ +G++ ++L Q TGG++ + L V +A+Q L+
Sbjct: 1458 GLINSNSGQRMTVEEAVREGVIDRDTASSILTYQVQTGGIIQSNPAKRLTVDEAVQCDLI 1517
Query: 105 GLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPA 164
+L A+R G P+ GE ++ +E++ L L + L P
Sbjct: 1518 TSSSALLVLEAQRGYVGLIWPHSGEIFPTSSSLQQELITNELAYKILNGRQKIAALYIPE 1577
Query: 165 QGVLVAPEPACHQGLLDRETWHKLSELE-----PGTGDL 198
++ + A G++D T L + P GDL
Sbjct: 1578 SSQVIGLDAAKQLGIIDNNTASILKNITLPDKMPDLGDL 1616
>gi|239749439 PREDICTED: similar to transcription factor 23 [Homo
sapiens]
Length = 167
Score = 43.9 bits (102), Expect = 0.004
Identities = 42/112 (37%), Positives = 57/112 (50%), Gaps = 18/112 (16%)
Query: 2578 AEEAPGARPQLQDARRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 2637
AE AP A ++D+R G PGPAG G G R G G + AAA AA R + QT
Sbjct: 15 AEPAPLAAA-IRDSRPGRTGPGPAGPGGGS-----RSGSG----RPAAANAARERSRVQT 64
Query: 2638 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 2681
LR A +E+QR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
Score = 40.8 bits (94), Expect = 0.035
Identities = 41/112 (36%), Positives = 56/112 (50%), Gaps = 18/112 (16%)
Query: 3112 AEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 3171
AE AP A ++D+ G PGPAG G G R G G + AAA AA R + QT
Sbjct: 15 AEPAPLAAA-IRDSRPGRTGPGPAGPGGGS-----RSGSG----RPAAANAARERSRVQT 64
Query: 3172 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 3215
LR A +E+QR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
Score = 40.8 bits (94), Expect = 0.035
Identities = 41/112 (36%), Positives = 56/112 (50%), Gaps = 18/112 (16%)
Query: 3646 AEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 3705
AE AP A ++D+ G PGPAG G G R G G + AAA AA R + QT
Sbjct: 15 AEPAPLAAA-IRDSRPGRTGPGPAGPGGGS-----RSGSG----RPAAANAARERSRVQT 64
Query: 3706 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 3749
LR A +E+QR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
Score = 40.8 bits (94), Expect = 0.035
Identities = 41/112 (36%), Positives = 56/112 (50%), Gaps = 18/112 (16%)
Query: 4714 AEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 4773
AE AP A ++D+ G PGPAG G G R G G + AAA AA R + QT
Sbjct: 15 AEPAPLAAA-IRDSRPGRTGPGPAGPGGGS-----RSGSG----RPAAANAARERSRVQT 64
Query: 4774 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 4817
LR A +E+QR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
Score = 39.3 bits (90), Expect = 0.10
Identities = 40/112 (35%), Positives = 55/112 (49%), Gaps = 18/112 (16%)
Query: 4180 AEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQT 4239
AE AP A ++D+ G PGPAG G G R G G + AAA A R + QT
Sbjct: 15 AEPAPLAAA-IRDSRPGRTGPGPAGPGGGS-----RSGSG----RPAAANAARERSRVQT 64
Query: 4240 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 4283
LR A +E+QR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
>gi|239743573 PREDICTED: similar to transcription factor 23 [Homo
sapiens]
Length = 167
Score = 43.9 bits (102), Expect = 0.004
Identities = 42/112 (37%), Positives = 57/112 (50%), Gaps = 18/112 (16%)
Query: 2578 AEEAPGARPQLQDARRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 2637
AE AP A ++D+R G PGPAG G G R G G + AAA AA R + QT
Sbjct: 15 AEPAPLAAA-IRDSRPGRTGPGPAGPGGGS-----RSGSG----RPAAANAARERSRVQT 64
Query: 2638 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 2681
LR A +E+QR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
Score = 40.8 bits (94), Expect = 0.035
Identities = 41/112 (36%), Positives = 56/112 (50%), Gaps = 18/112 (16%)
Query: 3112 AEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 3171
AE AP A ++D+ G PGPAG G G R G G + AAA AA R + QT
Sbjct: 15 AEPAPLAAA-IRDSRPGRTGPGPAGPGGGS-----RSGSG----RPAAANAARERSRVQT 64
Query: 3172 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 3215
LR A +E+QR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
Score = 40.8 bits (94), Expect = 0.035
Identities = 41/112 (36%), Positives = 56/112 (50%), Gaps = 18/112 (16%)
Query: 3646 AEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 3705
AE AP A ++D+ G PGPAG G G R G G + AAA AA R + QT
Sbjct: 15 AEPAPLAAA-IRDSRPGRTGPGPAGPGGGS-----RSGSG----RPAAANAARERSRVQT 64
Query: 3706 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 3749
LR A +E+QR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
Score = 40.8 bits (94), Expect = 0.035
Identities = 41/112 (36%), Positives = 56/112 (50%), Gaps = 18/112 (16%)
Query: 4714 AEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 4773
AE AP A ++D+ G PGPAG G G R G G + AAA AA R + QT
Sbjct: 15 AEPAPLAAA-IRDSRPGRTGPGPAGPGGGS-----RSGSG----RPAAANAARERSRVQT 64
Query: 4774 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 4817
LR A +E+QR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
Score = 39.3 bits (90), Expect = 0.10
Identities = 40/112 (35%), Positives = 55/112 (49%), Gaps = 18/112 (16%)
Query: 4180 AEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQT 4239
AE AP A ++D+ G PGPAG G G R G G + AAA A R + QT
Sbjct: 15 AEPAPLAAA-IRDSRPGRTGPGPAGPGGGS-----RSGSG----RPAAANAARERSRVQT 64
Query: 4240 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 4283
LR A +E+QR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
>gi|239754900 PREDICTED: similar to transcription factor 23 [Homo
sapiens]
Length = 167
Score = 41.2 bits (95), Expect = 0.027
Identities = 41/112 (36%), Positives = 53/112 (47%), Gaps = 18/112 (16%)
Query: 2578 AEEAPGARPQLQDARRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 2637
AE AP A ++D R G PGPAG G G S R AA AA R + QT
Sbjct: 15 AEPAPLAAA-IRDXRPGRTGPGPAGLGGGSCSGSGRP---------AAENAARERSRVQT 64
Query: 2638 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 2681
LR A +EVQR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLEVQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
Score = 38.1 bits (87), Expect = 0.23
Identities = 40/112 (35%), Positives = 52/112 (46%), Gaps = 18/112 (16%)
Query: 3112 AEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 3171
AE AP A ++D G PGPAG G G S R AA AA R + QT
Sbjct: 15 AEPAPLAAA-IRDXRPGRTGPGPAGLGGGSCSGSGRP---------AAENAARERSRVQT 64
Query: 3172 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 3215
LR A +EVQR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLEVQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
Score = 38.1 bits (87), Expect = 0.23
Identities = 40/112 (35%), Positives = 52/112 (46%), Gaps = 18/112 (16%)
Query: 3646 AEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 3705
AE AP A ++D G PGPAG G G S R AA AA R + QT
Sbjct: 15 AEPAPLAAA-IRDXRPGRTGPGPAGLGGGSCSGSGRP---------AAENAARERSRVQT 64
Query: 3706 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 3749
LR A +EVQR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLEVQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
Score = 38.1 bits (87), Expect = 0.23
Identities = 40/112 (35%), Positives = 52/112 (46%), Gaps = 18/112 (16%)
Query: 4714 AEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 4773
AE AP A ++D G PGPAG G G S R AA AA R + QT
Sbjct: 15 AEPAPLAAA-IRDXRPGRTGPGPAGLGGGSCSGSGRP---------AAENAARERSRVQT 64
Query: 4774 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 4817
LR A +EVQR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLEVQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
Score = 36.6 bits (83), Expect = 0.66
Identities = 39/112 (34%), Positives = 51/112 (45%), Gaps = 18/112 (16%)
Query: 4180 AEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQT 4239
AE AP A ++D G PGPAG G G S R AA A R + QT
Sbjct: 15 AEPAPLAAA-IRDXRPGRTGPGPAGLGGGSCSGSGRP---------AAENAARERSRVQT 64
Query: 4240 LRDATMEVQRGQFQGRP---VSVWDVL-----FSSYLSEARRDELLAQHAAG 4283
LR A +EVQR P +S DVL + ++L+ + +D+ A AG
Sbjct: 65 LRHAFLEVQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDAEAPADAG 116
>gi|239754110 PREDICTED: hypothetical protein XP_002345881 [Homo
sapiens]
Length = 284
Score = 39.7 bits (91), Expect = 0.077
Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 2508 SPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPAL 2567
+P P PRE R + VG + G V D+ A + + A G LPA
Sbjct: 89 APAPAPRERARGLRLRTVVG-VAGVLVERDDLHALLAIQVIVQLLCAAAEARGAATLPAA 147
Query: 2568 TRRLTAIIEEAEEAPGARPQLQDARRGPREPGPAGRGDGDSG-RSQREGQGEGETQEAAA 2626
TA+ + PGA + G G G G G G R R G+G GE
Sbjct: 148 AATTTAL-----DGPGAGGGAERGGSGRSSAGGGGGGGGGGGGRGSRRGRGGGE--RGGP 200
Query: 2627 AAAAARRQEQTLR 2639
A A RR+ LR
Sbjct: 201 RAQAVRRRLSALR 213
Score = 39.7 bits (91), Expect = 0.077
Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 3042 SPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPAL 3101
+P P PRE R + VG + G V D+ A + + A G LPA
Sbjct: 89 APAPAPRERARGLRLRTVVG-VAGVLVERDDLHALLAIQVIVQLLCAAAEARGAATLPAA 147
Query: 3102 TRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSG-RSQREGQGEGETQEAAA 3160
TA+ + PGA + G G G G G G R R G+G GE
Sbjct: 148 AATTTAL-----DGPGAGGGAERGGSGRSSAGGGGGGGGGGGGRGSRRGRGGGE--RGGP 200
Query: 3161 AAAAARRQEQTLR 3173
A A RR+ LR
Sbjct: 201 RAQAVRRRLSALR 213
Score = 39.7 bits (91), Expect = 0.077
Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 3576 SPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPAL 3635
+P P PRE R + VG + G V D+ A + + A G LPA
Sbjct: 89 APAPAPRERARGLRLRTVVG-VAGVLVERDDLHALLAIQVIVQLLCAAAEARGAATLPAA 147
Query: 3636 TRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSG-RSQREGQGEGETQEAAA 3694
TA+ + PGA + G G G G G G R R G+G GE
Sbjct: 148 AATTTAL-----DGPGAGGGAERGGSGRSSAGGGGGGGGGGGGRGSRRGRGGGE--RGGP 200
Query: 3695 AAAAARRQEQTLR 3707
A A RR+ LR
Sbjct: 201 RAQAVRRRLSALR 213
Score = 39.7 bits (91), Expect = 0.077
Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 4644 SPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPAL 4703
+P P PRE R + VG + G V D+ A + + A G LPA
Sbjct: 89 APAPAPRERARGLRLRTVVG-VAGVLVERDDLHALLAIQVIVQLLCAAAEARGAATLPAA 147
Query: 4704 TRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSG-RSQREGQGEGETQEAAA 4762
TA+ + PGA + G G G G G G R R G+G GE
Sbjct: 148 AATTTAL-----DGPGAGGGAERGGSGRSSAGGGGGGGGGGGGRGSRRGRGGGE--RGGP 200
Query: 4763 AAAAARRQEQTLR 4775
A A RR+ LR
Sbjct: 201 RAQAVRRRLSALR 213
Score = 38.1 bits (87), Expect = 0.23
Identities = 39/133 (29%), Positives = 50/133 (37%), Gaps = 9/133 (6%)
Query: 4110 SPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPAL 4169
+P P PRE R + VG + G V D+ A + + A G LPA
Sbjct: 89 APAPAPRERARGLRLRTVVG-VAGVLVERDDLHALLAIQVIVQLLCAAAEARGAATLPAA 147
Query: 4170 TRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSG-RSQREGQGEGETQEAAA 4228
TA+ + PGA + G G G G G G R R G+G GE
Sbjct: 148 AATTTAL-----DGPGAGGGAERGGSGRSSAGGGGGGGGGGGGRGSRRGRGGGE--RGGP 200
Query: 4229 ATAAARRQEQTLR 4241
A RR+ LR
Sbjct: 201 RAQAVRRRLSALR 213
>gi|239748639 PREDICTED: hypothetical protein XP_002346752 [Homo
sapiens]
Length = 286
Score = 38.9 bits (89), Expect = 0.13
Identities = 40/135 (29%), Positives = 52/135 (38%), Gaps = 11/135 (8%)
Query: 3042 SPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPAL 3101
+P P PRE R + VG + G V D+ A + + A G LPA
Sbjct: 89 APAPAPRERARGLRLRTVVG-VAGVLVERDDLHALLAIQVIVQLLCAAAEARGAATLPAA 147
Query: 3102 TRRLTAIIEEAEEAPGARPQLQDAWRGPREP---GPAGRGDGDSGRSQREGQGEGETQEA 3158
TA+ + PGA + + G G G G G GR R G+G GE
Sbjct: 148 AATTTAL-----DGPGAGGGAEAQFLGGGRSSAGGGGGGGGGGGGRGSRRGRGGGE--RG 200
Query: 3159 AAAAAAARRQEQTLR 3173
A A RR+ LR
Sbjct: 201 GPRAQAVRRRLSALR 215
Score = 38.9 bits (89), Expect = 0.13
Identities = 40/135 (29%), Positives = 52/135 (38%), Gaps = 11/135 (8%)
Query: 3576 SPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPAL 3635
+P P PRE R + VG + G V D+ A + + A G LPA
Sbjct: 89 APAPAPRERARGLRLRTVVG-VAGVLVERDDLHALLAIQVIVQLLCAAAEARGAATLPAA 147
Query: 3636 TRRLTAIIEEAEEAPGARPQLQDAWRGPREP---GPAGRGDGDSGRSQREGQGEGETQEA 3692
TA+ + PGA + + G G G G G GR R G+G GE
Sbjct: 148 AATTTAL-----DGPGAGGGAEAQFLGGGRSSAGGGGGGGGGGGGRGSRRGRGGGE--RG 200
Query: 3693 AAAAAAARRQEQTLR 3707
A A RR+ LR
Sbjct: 201 GPRAQAVRRRLSALR 215
Score = 38.9 bits (89), Expect = 0.13
Identities = 40/135 (29%), Positives = 52/135 (38%), Gaps = 11/135 (8%)
Query: 4644 SPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPAL 4703
+P P PRE R + VG + G V D+ A + + A G LPA
Sbjct: 89 APAPAPRERARGLRLRTVVG-VAGVLVERDDLHALLAIQVIVQLLCAAAEARGAATLPAA 147
Query: 4704 TRRLTAIIEEAEEAPGARPQLQDAWRGPREP---GPAGRGDGDSGRSQREGQGEGETQEA 4760
TA+ + PGA + + G G G G G GR R G+G GE
Sbjct: 148 AATTTAL-----DGPGAGGGAEAQFLGGGRSSAGGGGGGGGGGGGRGSRRGRGGGE--RG 200
Query: 4761 AAAAAAARRQEQTLR 4775
A A RR+ LR
Sbjct: 201 GPRAQAVRRRLSALR 215
Score = 38.5 bits (88), Expect = 0.17
Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 5/132 (3%)
Query: 2508 SPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPAL 2567
+P P PRE R + VG + G V D+ A + + A G LPA
Sbjct: 89 APAPAPRERARGLRLRTVVG-VAGVLVERDDLHALLAIQVIVQLLCAAAEARGAATLPAA 147
Query: 2568 TRRLTAIIEEAEEAPGARPQLQDARRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAA 2627
TA+ + GA Q R G G G G GR R G+G GE
Sbjct: 148 AATTTAL-DGPGAGGGAEAQFLGGGRSSAGGGGGG-GGGGGGRGSRRGRGGGE--RGGPR 203
Query: 2628 AAAARRQEQTLR 2639
A A RR+ LR
Sbjct: 204 AQAVRRRLSALR 215
Score = 37.4 bits (85), Expect = 0.38
Identities = 39/135 (28%), Positives = 51/135 (37%), Gaps = 11/135 (8%)
Query: 4110 SPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPAL 4169
+P P PRE R + VG + G V D+ A + + A G LPA
Sbjct: 89 APAPAPRERARGLRLRTVVG-VAGVLVERDDLHALLAIQVIVQLLCAAAEARGAATLPAA 147
Query: 4170 TRRLTAIIEEAEEAPGARPQLQDAWRGPREP---GPAGRGDGDSGRSQREGQGEGETQEA 4226
TA+ + PGA + + G G G G G GR R G+G GE
Sbjct: 148 AATTTAL-----DGPGAGGGAEAQFLGGGRSSAGGGGGGGGGGGGRGSRRGRGGGE--RG 200
Query: 4227 AAATAAARRQEQTLR 4241
A RR+ LR
Sbjct: 201 GPRAQAVRRRLSALR 215
>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
Length = 755
Score = 38.9 bits (89), Expect = 0.13
Identities = 88/339 (25%), Positives = 122/339 (35%), Gaps = 81/339 (23%)
Query: 2353 HSHRVPVDVAYRRGYFDEEMNRVLA-----DPSDDTKGFFDPNTHENLTYVQLLRRCVPD 2407
H+HRV V YR G++DEE A P + + P + L R C D
Sbjct: 142 HTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQ------LLCRECRLD 195
Query: 2408 PDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPG-SGALQGQSVSVWELLFYREVSED 2466
P L LA A+R R PG G L G ++ EL R V ++
Sbjct: 196 PHLDHPCLPLAE--------------AVRARR--PGLEGLLAGVDNNLVELEAARRVEKE 239
Query: 2467 RRQDLLSR-YRAGTLTVEELGATLTSLLAQAQ---AQARAEAEAGSPRPDPREALRAATM 2522
L + R GT E L +LLAQ Q Q RA EA EA R
Sbjct: 240 ALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAA------EEAARERLA 293
Query: 2523 EVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAP 2582
E++ RA + A +S E+L+ G A+ +RL ++ AP
Sbjct: 294 ELEGREQVARAAAAF---ARRVLSLGREAEILSLEG-------AIAQRLRQ-LQGCPWAP 342
Query: 2583 GARP--------------------QLQDARRGPREPG---PAGRGDGDSGRSQREG---- 2615
G P +L + P++ G AG G+ +S+RE
Sbjct: 343 GPAPCLLPQLELHPGLLDKNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKT 402
Query: 2616 --QGEGETQEAAAAAAAARRQEQTLRD---ATMEVQRGQ 2649
QG + Q A + QT R+ T+E R Q
Sbjct: 403 ERQGGVQPQAGDGAQTPKEEKAQTTREEGAQTLEEDRAQ 441
Score = 37.7 bits (86), Expect = 0.29
Identities = 89/331 (26%), Positives = 121/331 (36%), Gaps = 65/331 (19%)
Query: 2887 HSHRVPVDVAYRRGYFDEEMNRVLA-----DPSDDTKGFFDPNTHENLTYVQLLRRCVPD 2941
H+HRV V YR G++DEE A P + + P + L R C D
Sbjct: 142 HTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQ------LLCRECRLD 195
Query: 2942 PDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPG-SGALQGQSVSVWELLFYREVSED 3000
P L LA A+R R PG G L G ++ EL R V ++
Sbjct: 196 PHLDHPCLPLAE--------------AVRARR--PGLEGLLAGVDNNLVELEAARRVEKE 239
Query: 3001 RRQDLLSR-YRAGTLTVEELGATLTSLLAQAQ---AQARAEAEAGSPRPDPREALRAATM 3056
L + R GT E L +LLAQ Q Q RA EA RE R A +
Sbjct: 240 ALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEA--ARE--RLAEL 295
Query: 3057 EVKVGRLRGRAVPVWDVLASG------YVSGAAREELLAEFGSGTLDLPALTRRLTAIIE 3110
E + R A VL+ G + GA + L G PA ++
Sbjct: 296 EGREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPA-----PCLLP 350
Query: 3111 EAEEAPGARP------QLQDAWRGPREPG---PAGRGDGDSGRSQREG------QGEGET 3155
+ E PG +L + P++ G AG G+ +S+RE QG +
Sbjct: 351 QLELHPGLLDKNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQP 410
Query: 3156 QEAAAAAAAARRQEQTLRD---ATMEVQRGQ 3183
Q A + QT R+ T+E R Q
Sbjct: 411 QAGDGAQTPKEEKAQTTREEGAQTLEEDRAQ 441
Score = 37.7 bits (86), Expect = 0.29
Identities = 89/331 (26%), Positives = 121/331 (36%), Gaps = 65/331 (19%)
Query: 3421 HSHRVPVDVAYRRGYFDEEMNRVLA-----DPSDDTKGFFDPNTHENLTYVQLLRRCVPD 3475
H+HRV V YR G++DEE A P + + P + L R C D
Sbjct: 142 HTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQ------LLCRECRLD 195
Query: 3476 PDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPG-SGALQGQSVSVWELLFYREVSED 3534
P L LA A+R R PG G L G ++ EL R V ++
Sbjct: 196 PHLDHPCLPLAE--------------AVRARR--PGLEGLLAGVDNNLVELEAARRVEKE 239
Query: 3535 RRQDLLSR-YRAGTLTVEELGATLTSLLAQAQ---AQARAEAEAGSPRPDPREALRAATM 3590
L + R GT E L +LLAQ Q Q RA EA RE R A +
Sbjct: 240 ALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEA--ARE--RLAEL 295
Query: 3591 EVKVGRLRGRAVPVWDVLASG------YVSGAAREELLAEFGSGTLDLPALTRRLTAIIE 3644
E + R A VL+ G + GA + L G PA ++
Sbjct: 296 EGREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPA-----PCLLP 350
Query: 3645 EAEEAPGARP------QLQDAWRGPREPG---PAGRGDGDSGRSQREG------QGEGET 3689
+ E PG +L + P++ G AG G+ +S+RE QG +
Sbjct: 351 QLELHPGLLDKNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQP 410
Query: 3690 QEAAAAAAAARRQEQTLRD---ATMEVQRGQ 3717
Q A + QT R+ T+E R Q
Sbjct: 411 QAGDGAQTPKEEKAQTTREEGAQTLEEDRAQ 441
Score = 37.7 bits (86), Expect = 0.29
Identities = 89/331 (26%), Positives = 121/331 (36%), Gaps = 65/331 (19%)
Query: 4489 HSHRVPVDVAYRRGYFDEEMNRVLA-----DPSDDTKGFFDPNTHENLTYVQLLRRCVPD 4543
H+HRV V YR G++DEE A P + + P + L R C D
Sbjct: 142 HTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQ------LLCRECRLD 195
Query: 4544 PDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPG-SGALQGQSVSVWELLFYREVSED 4602
P L LA A+R R PG G L G ++ EL R V ++
Sbjct: 196 PHLDHPCLPLAE--------------AVRARR--PGLEGLLAGVDNNLVELEAARRVEKE 239
Query: 4603 RRQDLLSR-YRAGTLTVEELGATLTSLLAQAQ---AQARAEAEAGSPRPDPREALRAATM 4658
L + R GT E L +LLAQ Q Q RA EA RE R A +
Sbjct: 240 ALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEA--ARE--RLAEL 295
Query: 4659 EVKVGRLRGRAVPVWDVLASG------YVSGAAREELLAEFGSGTLDLPALTRRLTAIIE 4712
E + R A VL+ G + GA + L G PA ++
Sbjct: 296 EGREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPA-----PCLLP 350
Query: 4713 EAEEAPGARP------QLQDAWRGPREPG---PAGRGDGDSGRSQREG------QGEGET 4757
+ E PG +L + P++ G AG G+ +S+RE QG +
Sbjct: 351 QLELHPGLLDKNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQP 410
Query: 4758 QEAAAAAAAARRQEQTLRD---ATMEVQRGQ 4785
Q A + QT R+ T+E R Q
Sbjct: 411 QAGDGAQTPKEEKAQTTREEGAQTLEEDRAQ 441
Score = 35.4 bits (80), Expect = 1.5
Identities = 87/339 (25%), Positives = 121/339 (35%), Gaps = 81/339 (23%)
Query: 3955 HSHRVPVDVAYRRGYFDEEMNRVLA-----DPSDDTKGFFDPNTHENLTYVQLLRRCVPD 4009
H+HRV V YR G++DEE A P + + P + L R C D
Sbjct: 142 HTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQ------LLCRECRLD 195
Query: 4010 PDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPG-SGALQGQSVSVWELLFYREVSED 4068
P L LA A+R R PG G L G ++ EL R V ++
Sbjct: 196 PHLDHPCLPLAE--------------AVRARR--PGLEGLLAGVDNNLVELEAARRVEKE 239
Query: 4069 RRQDLLSR-YRASTLTVEELGATLTSLLAQAQ---AQARAEAEAGSPRPDPREALRAATM 4124
L + R T E L +LLAQ Q Q RA EA EA R
Sbjct: 240 ALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAA------EEAARERLA 293
Query: 4125 EVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAP 4184
E++ RA + A +S E+L+ G A+ +RL ++ AP
Sbjct: 294 ELEGREQVARAAAAF---ARRVLSLGREAEILSLEG-------AIAQRLRQ-LQGCPWAP 342
Query: 4185 GARP--------------------QLQDAWRGPREPG---PAGRGDGDSGRSQREG---- 4217
G P +L + P++ G AG G+ +S+RE
Sbjct: 343 GPAPCLLPQLELHPGLLDKNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKT 402
Query: 4218 --QGEGETQEAAAATAAARRQEQTLRD---ATMEVQRGQ 4251
QG + Q A + QT R+ T+E R Q
Sbjct: 403 ERQGGVQPQAGDGAQTPKEEKAQTTREEGAQTLEEDRAQ 441
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 38.5 bits (88), Expect = 0.17
Identities = 49/207 (23%), Positives = 86/207 (41%), Gaps = 23/207 (11%)
Query: 4061 FYREVSEDR--RQDLLSRYRASTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREA 4118
+ RE+ E R R ++ ++ + S ++ L A + L + + RA A R + +
Sbjct: 1657 YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADE 1716
Query: 4119 L------RAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRR 4172
+ ++A ++ K RL R + + L ++ E L F TL + L
Sbjct: 1717 ITNSASGKSALLDEK-RRLEARIAQLEEELEE---EQSNMELLNDRFRKTTLQVDTLNAE 1772
Query: 4173 LTAIIEEAEEAPGARPQL-----------QDAWRGPREPGPAGRGDGDSGRSQREGQGEG 4221
L A A+++ AR QL Q+ + A ++ Q E Q E
Sbjct: 1773 LAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQ 1832
Query: 4222 ETQEAAAATAAARRQEQTLRDATMEVQ 4248
E +E AAA RR E+ L++ M+V+
Sbjct: 1833 EAKERAAANKLVRRTEKKLKEIFMQVE 1859
Score = 37.4 bits (85), Expect = 0.38
Identities = 48/207 (23%), Positives = 85/207 (41%), Gaps = 23/207 (11%)
Query: 2459 FYREVSEDR--RQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREA 2516
+ RE+ E R R ++ ++ + ++ L A + L + + RA A R + +
Sbjct: 1657 YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADE 1716
Query: 2517 L------RAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRR 2570
+ ++A ++ K RL R + + L ++ E L F TL + L
Sbjct: 1717 ITNSASGKSALLDEK-RRLEARIAQLEEELEE---EQSNMELLNDRFRKTTLQVDTLNAE 1772
Query: 2571 LTAIIEEAEEAPGARPQL-----------QDARRGPREPGPAGRGDGDSGRSQREGQGEG 2619
L A A+++ AR QL Q+ + A ++ Q E Q E
Sbjct: 1773 LAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQ 1832
Query: 2620 ETQEAAAAAAAARRQEQTLRDATMEVQ 2646
E +E AAA RR E+ L++ M+V+
Sbjct: 1833 EAKERAAANKLVRRTEKKLKEIFMQVE 1859
Score = 35.0 bits (79), Expect = 1.9
Identities = 48/207 (23%), Positives = 84/207 (40%), Gaps = 23/207 (11%)
Query: 2993 FYREVSEDR--RQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREA 3050
+ RE+ E R R ++ ++ + ++ L A + L + + RA A R + +
Sbjct: 1657 YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADE 1716
Query: 3051 L------RAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRR 3104
+ ++A ++ K RL R + + L + E L F TL + L
Sbjct: 1717 ITNSASGKSALLDEK-RRLEARIAQLEEELEE---EQSNMELLNDRFRKTTLQVDTLNAE 1772
Query: 3105 LTAIIEEAEEAPGARPQL-----------QDAWRGPREPGPAGRGDGDSGRSQREGQGEG 3153
L A A+++ AR QL Q+ + A ++ Q E Q E
Sbjct: 1773 LAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQ 1832
Query: 3154 ETQEAAAAAAAARRQEQTLRDATMEVQ 3180
E +E AAA RR E+ L++ M+V+
Sbjct: 1833 EAKERAAANKLVRRTEKKLKEIFMQVE 1859
Score = 35.0 bits (79), Expect = 1.9
Identities = 48/207 (23%), Positives = 84/207 (40%), Gaps = 23/207 (11%)
Query: 3527 FYREVSEDR--RQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREA 3584
+ RE+ E R R ++ ++ + ++ L A + L + + RA A R + +
Sbjct: 1657 YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADE 1716
Query: 3585 L------RAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRR 3638
+ ++A ++ K RL R + + L + E L F TL + L
Sbjct: 1717 ITNSASGKSALLDEK-RRLEARIAQLEEELEE---EQSNMELLNDRFRKTTLQVDTLNAE 1772
Query: 3639 LTAIIEEAEEAPGARPQL-----------QDAWRGPREPGPAGRGDGDSGRSQREGQGEG 3687
L A A+++ AR QL Q+ + A ++ Q E Q E
Sbjct: 1773 LAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQ 1832
Query: 3688 ETQEAAAAAAAARRQEQTLRDATMEVQ 3714
E +E AAA RR E+ L++ M+V+
Sbjct: 1833 EAKERAAANKLVRRTEKKLKEIFMQVE 1859
Score = 35.0 bits (79), Expect = 1.9
Identities = 48/207 (23%), Positives = 84/207 (40%), Gaps = 23/207 (11%)
Query: 4595 FYREVSEDR--RQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREA 4652
+ RE+ E R R ++ ++ + ++ L A + L + + RA A R + +
Sbjct: 1657 YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADE 1716
Query: 4653 L------RAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRR 4706
+ ++A ++ K RL R + + L + E L F TL + L
Sbjct: 1717 ITNSASGKSALLDEK-RRLEARIAQLEEELEE---EQSNMELLNDRFRKTTLQVDTLNAE 1772
Query: 4707 LTAIIEEAEEAPGARPQL-----------QDAWRGPREPGPAGRGDGDSGRSQREGQGEG 4755
L A A+++ AR QL Q+ + A ++ Q E Q E
Sbjct: 1773 LAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQ 1832
Query: 4756 ETQEAAAAAAAARRQEQTLRDATMEVQ 4782
E +E AAA RR E+ L++ M+V+
Sbjct: 1833 EAKERAAANKLVRRTEKKLKEIFMQVE 1859
>gi|71274186 hypothetical protein LOC85449 [Homo sapiens]
Length = 1200
Score = 38.5 bits (88), Expect = 0.17
Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 13/172 (7%)
Query: 2436 RDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELG-ATLTSLLA 2494
R VTP +LQ W++L + R L + AGT + G AT S L
Sbjct: 480 RQPSVTPEKASLQHNGP--WKVLCSLYSPKPNRAKSLGK--AGTTQTKTSGPATAPSPLT 535
Query: 2495 QAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELL 2554
+ +A A EA AGSP P E ++G L + G RA R LL
Sbjct: 536 EEKA-ALPEASAGSPERGPTLEEEPPGPEPRIGALGVKVFRSRIACLPGGRDRAGRPLLL 594
Query: 2555 AEFGSGTLDLP-----ALTRRLTAI--IEEAEEAPGARPQLQDARRGPREPG 2599
G + P +T+ L+ + I E+ L DARR P +PG
Sbjct: 595 VSTTEGAWEAPWCTVSEVTKLLSYLCTIPRPEDKAKGLAVLIDARRQPPQPG 646
Score = 32.7 bits (73), Expect = 9.5
Identities = 48/172 (27%), Positives = 66/172 (38%), Gaps = 13/172 (7%)
Query: 2970 RDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELG-ATLTSLLA 3028
R VTP +LQ W++L + R L + AGT + G AT S L
Sbjct: 480 RQPSVTPEKASLQHNGP--WKVLCSLYSPKPNRAKSLGK--AGTTQTKTSGPATAPSPLT 535
Query: 3029 QAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELL 3088
+ +A A EA AGSP P E ++G L + G A R LL
Sbjct: 536 EEKA-ALPEASAGSPERGPTLEEEPPGPEPRIGALGVKVFRSRIACLPGGRDRAGRPLLL 594
Query: 3089 AEFGSGTLDLP-----ALTRRLTAI--IEEAEEAPGARPQLQDAWRGPREPG 3133
G + P +T+ L+ + I E+ L DA R P +PG
Sbjct: 595 VSTTEGAWEAPWCTVSEVTKLLSYLCTIPRPEDKAKGLAVLIDARRQPPQPG 646
Score = 32.7 bits (73), Expect = 9.5
Identities = 48/172 (27%), Positives = 66/172 (38%), Gaps = 13/172 (7%)
Query: 3504 RDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELG-ATLTSLLA 3562
R VTP +LQ W++L + R L + AGT + G AT S L
Sbjct: 480 RQPSVTPEKASLQHNGP--WKVLCSLYSPKPNRAKSLGK--AGTTQTKTSGPATAPSPLT 535
Query: 3563 QAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELL 3622
+ +A A EA AGSP P E ++G L + G A R LL
Sbjct: 536 EEKA-ALPEASAGSPERGPTLEEEPPGPEPRIGALGVKVFRSRIACLPGGRDRAGRPLLL 594
Query: 3623 AEFGSGTLDLP-----ALTRRLTAI--IEEAEEAPGARPQLQDAWRGPREPG 3667
G + P +T+ L+ + I E+ L DA R P +PG
Sbjct: 595 VSTTEGAWEAPWCTVSEVTKLLSYLCTIPRPEDKAKGLAVLIDARRQPPQPG 646
Score = 32.7 bits (73), Expect = 9.5
Identities = 48/172 (27%), Positives = 66/172 (38%), Gaps = 13/172 (7%)
Query: 4572 RDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELG-ATLTSLLA 4630
R VTP +LQ W++L + R L + AGT + G AT S L
Sbjct: 480 RQPSVTPEKASLQHNGP--WKVLCSLYSPKPNRAKSLGK--AGTTQTKTSGPATAPSPLT 535
Query: 4631 QAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELL 4690
+ +A A EA AGSP P E ++G L + G A R LL
Sbjct: 536 EEKA-ALPEASAGSPERGPTLEEEPPGPEPRIGALGVKVFRSRIACLPGGRDRAGRPLLL 594
Query: 4691 AEFGSGTLDLP-----ALTRRLTAI--IEEAEEAPGARPQLQDAWRGPREPG 4735
G + P +T+ L+ + I E+ L DA R P +PG
Sbjct: 595 VSTTEGAWEAPWCTVSEVTKLLSYLCTIPRPEDKAKGLAVLIDARRQPPQPG 646
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 37.0 bits (84), Expect = 0.50
Identities = 22/84 (26%), Positives = 34/84 (40%), Gaps = 8/84 (9%)
Query: 3111 EAEEAPGARPQLQDAWRGPREPGPA-----GRGDGDSGRSQ---REGQGEGETQEAAAAA 3162
E E+ G + + W G E G G G+G+ G + EG+GEGE +E
Sbjct: 940 EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEG 999
Query: 3163 AAARRQEQTLRDATMEVQRGQFQG 3186
E+ E + G+ +G
Sbjct: 1000 EEEGEGEEEGEGEGEEEEEGEVEG 1023
Score = 37.0 bits (84), Expect = 0.50
Identities = 22/84 (26%), Positives = 34/84 (40%), Gaps = 8/84 (9%)
Query: 3645 EAEEAPGARPQLQDAWRGPREPGPA-----GRGDGDSGRSQ---REGQGEGETQEAAAAA 3696
E E+ G + + W G E G G G+G+ G + EG+GEGE +E
Sbjct: 940 EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEG 999
Query: 3697 AAARRQEQTLRDATMEVQRGQFQG 3720
E+ E + G+ +G
Sbjct: 1000 EEEGEGEEEGEGEGEEEEEGEVEG 1023
Score = 37.0 bits (84), Expect = 0.50
Identities = 22/84 (26%), Positives = 34/84 (40%), Gaps = 8/84 (9%)
Query: 4713 EAEEAPGARPQLQDAWRGPREPGPA-----GRGDGDSGRSQ---REGQGEGETQEAAAAA 4764
E E+ G + + W G E G G G+G+ G + EG+GEGE +E
Sbjct: 940 EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEG 999
Query: 4765 AAARRQEQTLRDATMEVQRGQFQG 4788
E+ E + G+ +G
Sbjct: 1000 EEEGEGEEEGEGEGEEEEEGEVEG 1023
Score = 36.2 bits (82), Expect = 0.86
Identities = 22/84 (26%), Positives = 34/84 (40%), Gaps = 8/84 (9%)
Query: 4179 EAEEAPGARPQLQDAWRGPREPGPA-----GRGDGDSGRSQ---REGQGEGETQEAAAAT 4230
E E+ G + + W G E G G G+G+ G + EG+GEGE +E
Sbjct: 940 EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEG 999
Query: 4231 AAARRQEQTLRDATMEVQRGQFQG 4254
E+ E + G+ +G
Sbjct: 1000 EEEGEGEEEGEGEGEEEEEGEVEG 1023
Score = 32.7 bits (73), Expect = 9.5
Identities = 16/48 (33%), Positives = 22/48 (45%)
Query: 2576 EEAEEAPGARPQLQDARRGPREPGPAGRGDGDSGRSQREGQGEGETQE 2623
EE EE G + + G E G + G + EG+GEGE +E
Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
Score = 32.7 bits (73), Expect = 9.5
Identities = 16/48 (33%), Positives = 22/48 (45%)
Query: 3110 EEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQE 3157
EE EE G + + G E G + G + EG+GEGE +E
Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
Score = 32.7 bits (73), Expect = 9.5
Identities = 16/48 (33%), Positives = 22/48 (45%)
Query: 3644 EEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQE 3691
EE EE G + + G E G + G + EG+GEGE +E
Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
Score = 32.7 bits (73), Expect = 9.5
Identities = 16/48 (33%), Positives = 22/48 (45%)
Query: 4178 EEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQE 4225
EE EE G + + G E G + G + EG+GEGE +E
Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
Score = 32.7 bits (73), Expect = 9.5
Identities = 16/48 (33%), Positives = 22/48 (45%)
Query: 4712 EEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQE 4759
EE EE G + + G E G + G + EG+GEGE +E
Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo
sapiens]
Length = 958
Score = 36.6 bits (83), Expect = 0.66
Identities = 50/168 (29%), Positives = 77/168 (45%), Gaps = 25/168 (14%)
Query: 3015 TVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVL 3074
T+ G +T A AQA+ R+ ++ P +P+ + A V + G+AV
Sbjct: 805 TISAPGKVVT---AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV-GKAVATAAQA 860
Query: 3075 ASGYV--SGAAREELLAEFGSGTLDL---PALTRRLTAIIEEAEEAP--GARPQLQDAWR 3127
+G SG++ EE +E + TL T ++ A + A+E+P GA P
Sbjct: 861 QTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT------ 914
Query: 3128 GPREPGP----AGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 3171
P + GP AG+ D DSG S E +G EA AA +A+ QE +
Sbjct: 915 PPGKTGPSAAQAGKQD-DSGSSSEESDSDG---EAPAAVTSAQDQESS 958
Score = 36.6 bits (83), Expect = 0.66
Identities = 50/168 (29%), Positives = 77/168 (45%), Gaps = 25/168 (14%)
Query: 3549 TVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVL 3608
T+ G +T A AQA+ R+ ++ P +P+ + A V + G+AV
Sbjct: 805 TISAPGKVVT---AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV-GKAVATAAQA 860
Query: 3609 ASGYV--SGAAREELLAEFGSGTLDL---PALTRRLTAIIEEAEEAP--GARPQLQDAWR 3661
+G SG++ EE +E + TL T ++ A + A+E+P GA P
Sbjct: 861 QTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT------ 914
Query: 3662 GPREPGP----AGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 3705
P + GP AG+ D DSG S E +G EA AA +A+ QE +
Sbjct: 915 PPGKTGPSAAQAGKQD-DSGSSSEESDSDG---EAPAAVTSAQDQESS 958
Score = 36.6 bits (83), Expect = 0.66
Identities = 50/168 (29%), Positives = 77/168 (45%), Gaps = 25/168 (14%)
Query: 4617 TVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVL 4676
T+ G +T A AQA+ R+ ++ P +P+ + A V + G+AV
Sbjct: 805 TISAPGKVVT---AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV-GKAVATAAQA 860
Query: 4677 ASGYV--SGAAREELLAEFGSGTLDL---PALTRRLTAIIEEAEEAP--GARPQLQDAWR 4729
+G SG++ EE +E + TL T ++ A + A+E+P GA P
Sbjct: 861 QTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT------ 914
Query: 4730 GPREPGP----AGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 4773
P + GP AG+ D DSG S E +G EA AA +A+ QE +
Sbjct: 915 PPGKTGPSAAQAGKQD-DSGSSSEESDSDG---EAPAAVTSAQDQESS 958
Score = 34.3 bits (77), Expect = 3.3
Identities = 48/164 (29%), Positives = 75/164 (45%), Gaps = 17/164 (10%)
Query: 2481 TVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVL 2540
T+ G +T A AQA+ R+ ++ P +P+ + A V + G+AV
Sbjct: 805 TISAPGKVVT---AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV-GKAVATAAQA 860
Query: 2541 ASGYV--SRAAREELLAEFGSGTLDL---PALTRRLTAIIEEAEEAP--GARPQLQDARR 2593
+G S ++ EE +E + TL T ++ A + A+E+P GA P +
Sbjct: 861 QTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT-PPGKT 919
Query: 2594 GPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAARRQEQT 2637
GP AG+ D DSG S E +G EA AA +A+ QE +
Sbjct: 920 GP-SAAQAGKQD-DSGSSSEESDSDG---EAPAAVTSAQDQESS 958
>gi|55749708 outer dense fiber of sperm tails 2-like isoform b [Homo
sapiens]
Length = 513
Score = 36.6 bits (83), Expect = 0.66
Identities = 35/141 (24%), Positives = 65/141 (46%), Gaps = 16/141 (11%)
Query: 1758 QIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTEDRKRELIQEY 1817
+I++K + Y NE L++ K + D+VVS + LS E +++ LI+ Y
Sbjct: 198 EILRKVHSIEYENETLN--LENTKLKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMY 255
Query: 1818 GAQSGGLEKLLEIITTTIEE--------TETQNQGIKVAAIRGEVTAADLFNSRVIDQKT 1869
Q L++ EI+ + E T+T+N+ ++ +RG++ + RV D T
Sbjct: 256 KTQVQKLQEAAEIVKSRCENLLHKNNQITKTKNKNVE--KMRGQMESHLKELERVCDSLT 313
Query: 1870 LHTLRVGRTGGQALSTLECVK 1890
R+ + +L+C K
Sbjct: 314 AAERRL----HECQESLQCCK 330
>gi|55749696 outer dense fiber of sperm tails 2-like isoform a [Homo
sapiens]
Length = 644
Score = 36.6 bits (83), Expect = 0.66
Identities = 35/141 (24%), Positives = 65/141 (46%), Gaps = 16/141 (11%)
Query: 1758 QIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTEDRKRELIQEY 1817
+I++K + Y NE L++ K + D+VVS + LS E +++ LI+ Y
Sbjct: 329 EILRKVHSIEYENETLN--LENTKLKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMY 386
Query: 1818 GAQSGGLEKLLEIITTTIEE--------TETQNQGIKVAAIRGEVTAADLFNSRVIDQKT 1869
Q L++ EI+ + E T+T+N+ ++ +RG++ + RV D T
Sbjct: 387 KTQVQKLQEAAEIVKSRCENLLHKNNQITKTKNKNVE--KMRGQMESHLKELERVCDSLT 444
Query: 1870 LHTLRVGRTGGQALSTLECVK 1890
R+ + +L+C K
Sbjct: 445 AAERRL----HECQESLQCCK 461
>gi|222537747 hypothetical protein LOC342979 [Homo sapiens]
Length = 673
Score = 36.2 bits (82), Expect = 0.86
Identities = 43/159 (27%), Positives = 61/159 (38%), Gaps = 43/159 (27%)
Query: 2500 ARAEAEAGSPRPDPREAL--RAATMEVKVGRLRGRAVP--VWDVL---------ASGYVS 2546
+ A SP P P + L RA E +VG +G V VW+ L A+G
Sbjct: 181 SEANGPCPSPIPTPEQGLSQRAVPSEGRVGEAKGGGVVSVVWEGLRATEDCATGATGPEL 240
Query: 2547 RAAREELLAEF-----GSGTLDLPALTRRLTAIIEEAEEAPG------------------ 2583
A EE++ E G+G+L+LPA + I+E E G
Sbjct: 241 EAKVEEVVLEAIGDRKGAGSLELPAWVKEDRGIVEVVWEGVGGSDAEAMGEIGRVPEVVQ 300
Query: 2584 -ARPQLQD------ARRGPREPGPAGRGDGDSGRSQREG 2615
+ P+LQ+ + G P + GDG G EG
Sbjct: 301 TSSPRLQERLEAAASIEGEDVPQGSPEGDGQGGSGGEEG 339
Score = 36.2 bits (82), Expect = 0.86
Identities = 43/159 (27%), Positives = 61/159 (38%), Gaps = 43/159 (27%)
Query: 4102 ARAEAEAGSPRPDPREAL--RAATMEVKVGRLRGRAVP--VWDVL---------ASGYVS 4148
+ A SP P P + L RA E +VG +G V VW+ L A+G
Sbjct: 181 SEANGPCPSPIPTPEQGLSQRAVPSEGRVGEAKGGGVVSVVWEGLRATEDCATGATGPEL 240
Query: 4149 RAAREELLAEF-----GSGTLDLPALTRRLTAIIEEAEEAPG------------------ 4185
A EE++ E G+G+L+LPA + I+E E G
Sbjct: 241 EAKVEEVVLEAIGDRKGAGSLELPAWVKEDRGIVEVVWEGVGGSDAEAMGEIGRVPEVVQ 300
Query: 4186 -ARPQLQD------AWRGPREPGPAGRGDGDSGRSQREG 4217
+ P+LQ+ + G P + GDG G EG
Sbjct: 301 TSSPRLQERLEAAASIEGEDVPQGSPEGDGQGGSGGEEG 339
Score = 35.4 bits (80), Expect = 1.5
Identities = 43/159 (27%), Positives = 61/159 (38%), Gaps = 43/159 (27%)
Query: 3034 ARAEAEAGSPRPDPREAL--RAATMEVKVGRLRGRAVP--VWDVL---------ASGYVS 3080
+ A SP P P + L RA E +VG +G V VW+ L A+G
Sbjct: 181 SEANGPCPSPIPTPEQGLSQRAVPSEGRVGEAKGGGVVSVVWEGLRATEDCATGATGPEL 240
Query: 3081 GAAREELLAEF-----GSGTLDLPALTRRLTAIIEEAEEAPG------------------ 3117
A EE++ E G+G+L+LPA + I+E E G
Sbjct: 241 EAKVEEVVLEAIGDRKGAGSLELPAWVKEDRGIVEVVWEGVGGSDAEAMGEIGRVPEVVQ 300
Query: 3118 -ARPQLQD------AWRGPREPGPAGRGDGDSGRSQREG 3149
+ P+LQ+ + G P + GDG G EG
Sbjct: 301 TSSPRLQERLEAAASIEGEDVPQGSPEGDGQGGSGGEEG 339
Score = 35.4 bits (80), Expect = 1.5
Identities = 43/159 (27%), Positives = 61/159 (38%), Gaps = 43/159 (27%)
Query: 3568 ARAEAEAGSPRPDPREAL--RAATMEVKVGRLRGRAVP--VWDVL---------ASGYVS 3614
+ A SP P P + L RA E +VG +G V VW+ L A+G
Sbjct: 181 SEANGPCPSPIPTPEQGLSQRAVPSEGRVGEAKGGGVVSVVWEGLRATEDCATGATGPEL 240
Query: 3615 GAAREELLAEF-----GSGTLDLPALTRRLTAIIEEAEEAPG------------------ 3651
A EE++ E G+G+L+LPA + I+E E G
Sbjct: 241 EAKVEEVVLEAIGDRKGAGSLELPAWVKEDRGIVEVVWEGVGGSDAEAMGEIGRVPEVVQ 300
Query: 3652 -ARPQLQD------AWRGPREPGPAGRGDGDSGRSQREG 3683
+ P+LQ+ + G P + GDG G EG
Sbjct: 301 TSSPRLQERLEAAASIEGEDVPQGSPEGDGQGGSGGEEG 339
Score = 35.4 bits (80), Expect = 1.5
Identities = 43/159 (27%), Positives = 61/159 (38%), Gaps = 43/159 (27%)
Query: 4636 ARAEAEAGSPRPDPREAL--RAATMEVKVGRLRGRAVP--VWDVL---------ASGYVS 4682
+ A SP P P + L RA E +VG +G V VW+ L A+G
Sbjct: 181 SEANGPCPSPIPTPEQGLSQRAVPSEGRVGEAKGGGVVSVVWEGLRATEDCATGATGPEL 240
Query: 4683 GAAREELLAEF-----GSGTLDLPALTRRLTAIIEEAEEAPG------------------ 4719
A EE++ E G+G+L+LPA + I+E E G
Sbjct: 241 EAKVEEVVLEAIGDRKGAGSLELPAWVKEDRGIVEVVWEGVGGSDAEAMGEIGRVPEVVQ 300
Query: 4720 -ARPQLQD------AWRGPREPGPAGRGDGDSGRSQREG 4751
+ P+LQ+ + G P + GDG G EG
Sbjct: 301 TSSPRLQERLEAAASIEGEDVPQGSPEGDGQGGSGGEEG 339
>gi|169214874 PREDICTED: hypothetical protein [Homo sapiens]
Length = 583
Score = 36.2 bits (82), Expect = 0.86
Identities = 25/75 (33%), Positives = 31/75 (41%), Gaps = 13/75 (17%)
Query: 2578 AEEAPGARPQLQDARRGPREPGPAGRGDGD-------------SGRSQREGQGEGETQEA 2624
A APG + R G P AGR G+ GR + +G E E QE
Sbjct: 94 ARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEP 153
Query: 2625 AAAAAAARRQEQTLR 2639
A AAA R+ Q L+
Sbjct: 154 ELAGAAAGREPQRLQ 168
Score = 33.1 bits (74), Expect = 7.2
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 13/75 (17%)
Query: 3112 AEEAPGARPQLQDAWRGPREPGPAGRGDGD-------------SGRSQREGQGEGETQEA 3158
A APG + G P AGR G+ GR + +G E E QE
Sbjct: 94 ARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEP 153
Query: 3159 AAAAAAARRQEQTLR 3173
A AAA R+ Q L+
Sbjct: 154 ELAGAAAGREPQRLQ 168
Score = 33.1 bits (74), Expect = 7.2
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 13/75 (17%)
Query: 3646 AEEAPGARPQLQDAWRGPREPGPAGRGDGD-------------SGRSQREGQGEGETQEA 3692
A APG + G P AGR G+ GR + +G E E QE
Sbjct: 94 ARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEP 153
Query: 3693 AAAAAAARRQEQTLR 3707
A AAA R+ Q L+
Sbjct: 154 ELAGAAAGREPQRLQ 168
Score = 33.1 bits (74), Expect = 7.2
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 13/75 (17%)
Query: 4714 AEEAPGARPQLQDAWRGPREPGPAGRGDGD-------------SGRSQREGQGEGETQEA 4760
A APG + G P AGR G+ GR + +G E E QE
Sbjct: 94 ARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEP 153
Query: 4761 AAAAAAARRQEQTLR 4775
A AAA R+ Q L+
Sbjct: 154 ELAGAAAGREPQRLQ 168
>gi|169215109 PREDICTED: hypothetical protein [Homo sapiens]
Length = 583
Score = 36.2 bits (82), Expect = 0.86
Identities = 25/75 (33%), Positives = 31/75 (41%), Gaps = 13/75 (17%)
Query: 2578 AEEAPGARPQLQDARRGPREPGPAGRGDGD-------------SGRSQREGQGEGETQEA 2624
A APG + R G P AGR G+ GR + +G E E QE
Sbjct: 94 ARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEP 153
Query: 2625 AAAAAAARRQEQTLR 2639
A AAA R+ Q L+
Sbjct: 154 ELAGAAAGREPQRLQ 168
Score = 33.1 bits (74), Expect = 7.2
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 13/75 (17%)
Query: 3112 AEEAPGARPQLQDAWRGPREPGPAGRGDGD-------------SGRSQREGQGEGETQEA 3158
A APG + G P AGR G+ GR + +G E E QE
Sbjct: 94 ARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEP 153
Query: 3159 AAAAAAARRQEQTLR 3173
A AAA R+ Q L+
Sbjct: 154 ELAGAAAGREPQRLQ 168
Score = 33.1 bits (74), Expect = 7.2
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 13/75 (17%)
Query: 3646 AEEAPGARPQLQDAWRGPREPGPAGRGDGD-------------SGRSQREGQGEGETQEA 3692
A APG + G P AGR G+ GR + +G E E QE
Sbjct: 94 ARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEP 153
Query: 3693 AAAAAAARRQEQTLR 3707
A AAA R+ Q L+
Sbjct: 154 ELAGAAAGREPQRLQ 168
Score = 33.1 bits (74), Expect = 7.2
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 13/75 (17%)
Query: 4714 AEEAPGARPQLQDAWRGPREPGPAGRGDGD-------------SGRSQREGQGEGETQEA 4760
A APG + G P AGR G+ GR + +G E E QE
Sbjct: 94 ARGAPGDHVAIAHRRHGDDSPPVAGRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEP 153
Query: 4761 AAAAAAARRQEQTLR 4775
A AAA R+ Q L+
Sbjct: 154 ELAGAAAGREPQRLQ 168
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 190,815,501
Number of Sequences: 37866
Number of extensions: 9024324
Number of successful extensions: 45004
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 36094
Number of HSP's gapped (non-prelim): 2256
length of query: 5090
length of database: 18,247,518
effective HSP length: 124
effective length of query: 4966
effective length of database: 13,552,134
effective search space: 67299897444
effective search space used: 67299897444
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.