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Search of human proteins with 207450721
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|207450721 ganglioside induced differentiation associated
protein 2 isoform b [Homo sapiens]
(496 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|207450721 ganglioside induced differentiation associated prot... 996 0.0
gi|8923143 ganglioside induced differentiation associated protei... 970 0.0
gi|13569840 MACRO domain containing 1 [Homo sapiens] 122 1e-27
gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens] 120 2e-27
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens] 84 4e-16
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens] 74 2e-13
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi... 74 2e-13
gi|29336043 caytaxin [Homo sapiens] 63 7e-10
gi|162287219 prune homolog 2 [Homo sapiens] 60 3e-09
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi... 59 1e-08
gi|168480080 BCL2/adenovirus E1B 19kD interacting protein 2 [Hom... 55 1e-07
gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens] 55 1e-07
gi|4758496 H2A histone family, member Y isoform 2 [Homo sapiens] 54 3e-07
gi|93141020 H2A histone family, member Y isoform 2 [Homo sapiens] 54 3e-07
gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens] 54 3e-07
gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Hom... 52 1e-06
gi|228008343 BCL2/adenovirus E1B 19kD interacting protein like i... 52 2e-06
gi|109715844 BCL2/adenovirus E1B 19kD interacting protein like i... 52 2e-06
gi|8923920 H2A histone family, member Y2 [Homo sapiens] 48 2e-05
gi|226371718 poly (ADP-ribose) polymerase family, member 9 isofo... 48 2e-05
gi|226371716 poly (ADP-ribose) polymerase family, member 9 isofo... 48 2e-05
gi|226371714 poly (ADP-ribose) polymerase family, member 9 isofo... 48 2e-05
gi|226371712 poly (ADP-ribose) polymerase family, member 9 isofo... 48 2e-05
gi|226371710 poly (ADP-ribose) polymerase family, member 9 isofo... 48 2e-05
gi|226371706 poly (ADP-ribose) polymerase family, member 9 isofo... 48 2e-05
gi|109826564 neurofibromin isoform 1 [Homo sapiens] 40 0.004
gi|4557793 neurofibromin isoform 2 [Homo sapiens] 40 0.004
gi|165377137 poly (ADP-ribose) polymerase family, member 15 isof... 39 0.014
gi|4506541 retinaldehyde binding protein 1 [Homo sapiens] 33 0.60
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens] 32 1.3
>gi|207450721 ganglioside induced differentiation associated protein
2 isoform b [Homo sapiens]
Length = 496
Score = 996 bits (2574), Expect = 0.0
Identities = 496/496 (100%), Positives = 496/496 (100%)
Query: 1 MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWK 60
MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWK
Sbjct: 1 MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWK 60
Query: 61 GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL
Sbjct: 61 GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
Query: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLED 180
AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLED
Sbjct: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLED 180
Query: 181 ATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPAD 240
ATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPAD
Sbjct: 181 ATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPAD 240
Query: 241 IGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKL 300
IGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKL
Sbjct: 241 IGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKL 300
Query: 301 ILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNI 360
ILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNI
Sbjct: 301 ILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNI 360
Query: 361 PVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRN 420
PVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRN
Sbjct: 361 PVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRN 420
Query: 421 LKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD 480
LKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD
Sbjct: 421 LKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD 480
Query: 481 ARVRSTRSSPSPGMVY 496
ARVRSTRSSPSPGMVY
Sbjct: 481 ARVRSTRSSPSPGMVY 496
>gi|8923143 ganglioside induced differentiation associated protein 2
isoform a [Homo sapiens]
Length = 497
Score = 970 bits (2507), Expect = 0.0
Identities = 486/497 (97%), Positives = 487/497 (97%), Gaps = 3/497 (0%)
Query: 1 MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWK 60
MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWK
Sbjct: 1 MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWK 60
Query: 61 GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL
Sbjct: 61 GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
Query: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLED 180
AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLED
Sbjct: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLED 180
Query: 181 ATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPAD 240
ATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPAD
Sbjct: 181 ATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPAD 240
Query: 241 IGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKL 300
IGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKL
Sbjct: 241 IGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKL 300
Query: 301 ILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNI 360
ILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNI
Sbjct: 301 ILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNI 360
Query: 361 PVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRN 420
PVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRN
Sbjct: 361 PVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRN 420
Query: 421 LKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD 480
LKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD
Sbjct: 421 LKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD 480
Query: 481 ARVRS---TRSSPSPGM 494
AR T PSP +
Sbjct: 481 ARENGPYYTSYPPSPDL 497
>gi|13569840 MACRO domain containing 1 [Homo sapiens]
Length = 325
Score = 122 bits (305), Expect = 1e-27
Identities = 66/177 (37%), Positives = 100/177 (56%), Gaps = 1/177 (0%)
Query: 49 NKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCR 108
+K +N K+ L + D+ L AIVN +N SL V I AGP L ++ + L+ C+
Sbjct: 147 DKQLNEKISLLRSDITKLEVDAIVNAANSSLLGGGGVDGCIHRAAGPLLTDECRTLQSCK 206
Query: 109 TGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCV 168
TG+AK+T G+ L A+++IHTVGP + + L SCY + L L E + SV F
Sbjct: 207 TGKAKITGGYRLPAKYVIHTVGPIAYGEPSASQAAELRSCYLSSLDLLLEHRLRSVAFPC 266
Query: 169 INSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAV-SDLEEGTYQKLLPLYFP 224
I++ GYP E A I L T+R +LE H + +++++ V + +E Y+ LP YFP
Sbjct: 267 ISTGVFGYPCEAAAEIVLATLREWLEQHKDKVDRLIICVFLEKDEDIYRSRLPHYFP 323
>gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens]
Length = 425
Score = 120 bits (302), Expect = 2e-27
Identities = 79/264 (29%), Positives = 131/264 (49%), Gaps = 27/264 (10%)
Query: 10 FVDVDTLPSWGDSCQDE-LNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNC 68
++ ++++ SW + + + N + T E Q K + KV L++GD+ LL
Sbjct: 34 YIPLNSILSWKEEMKGKGQNDEENTQETSQ---------VKKSLTEKVSLYRGDITLLEV 84
Query: 69 TAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNLAARFIIHT 128
AIVN +N SL V I AGP L + + L GC TG AK+T G++L A+++IHT
Sbjct: 85 DAIVNAANASLLGGGGVDGCIHRAAGPCLLAECRNLNGCDTGHAKITCGYDLPAKYVIHT 144
Query: 129 VGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRT 188
VGP + + + L +CY++ L+L KE ++ SV F I++ G+P E A IAL T
Sbjct: 145 VGPIARGHINGSHKEDLANCYKSSLKLVKENNIRSVAFPCISTGIYGFPNEPAAVIALNT 204
Query: 189 VRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPADIGNAEGEP 248
++ +L + +++++F V L + F K+ N + D N E E
Sbjct: 205 IKEWLAKNHHEVDRIIFCV----------FLEVDFKIYKKKMNE---FFSVDDNNEEEED 251
Query: 249 VVPERQIRISEKPGAPEDNQEEED 272
V +++ PE+ Q E+
Sbjct: 252 V----EMKEDSDENGPEEKQSVEE 271
>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
Length = 439
Score = 83.6 bits (205), Expect = 4e-16
Identities = 52/160 (32%), Positives = 78/160 (48%), Gaps = 1/160 (0%)
Query: 333 DIASLKALYQTGVDNCGRTVMVVVGRNIPVT-LIDMDKALLYFIHVMDHIAVKEYVLVYF 391
DIA + + G D GR ++V +P + +D K L Y H +D +Y L+Y
Sbjct: 66 DIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYL 125
Query: 392 HTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDK 451
H + N +L+ Y D KYK+N+KA+Y VHPT K F K
Sbjct: 126 HHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQK 185
Query: 452 IHHVDSLHQLFSAISPEQIDFPPFVLEYDARVRSTRSSPS 491
I +V+ L +L + EQ+ P VL+YD ++ST+ SP+
Sbjct: 186 IFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPA 225
>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
Length = 555
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/166 (29%), Positives = 75/166 (45%), Gaps = 1/166 (0%)
Query: 328 SEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTL-IDMDKALLYFIHVMDHIAVKEY 386
S D+A L G D GR V+ +P + +D + L Y + +D +Y
Sbjct: 133 SHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDY 192
Query: 387 VLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVS 446
+VYFH + N +L+ Y D KYK+NLKA+Y VHPT KV
Sbjct: 193 TIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLISH 252
Query: 447 GLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYDARVRSTRSSPSP 492
K+ + + L +L + +Q+ PP VL YD +++S +P
Sbjct: 253 KFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTP 298
>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo
sapiens]
Length = 433
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/166 (29%), Positives = 75/166 (45%), Gaps = 1/166 (0%)
Query: 328 SEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTL-IDMDKALLYFIHVMDHIAVKEY 386
S D+A L G D GR V+ +P + +D + L Y + +D +Y
Sbjct: 11 SHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDY 70
Query: 387 VLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVS 446
+VYFH + N +L+ Y D KYK+NLKA+Y VHPT KV
Sbjct: 71 TIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLISH 130
Query: 447 GLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYDARVRSTRSSPSP 492
K+ + + L +L + +Q+ PP VL YD +++S +P
Sbjct: 131 KFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTP 176
>gi|29336043 caytaxin [Homo sapiens]
Length = 371
Score = 62.8 bits (151), Expect = 7e-10
Identities = 36/127 (28%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Query: 367 MDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYF 426
M+ LY I ++ + ++Y++VY + T +LKK Y ++D + ++NLK++
Sbjct: 211 MENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLII 270
Query: 427 VHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEY-DARVRS 485
VHP++ + F +KI +V SL L I E + P VL+Y + R+++
Sbjct: 271 VHPSWFIRTVLAISRPFISVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKA 330
Query: 486 TRSSPSP 492
R S P
Sbjct: 331 RRESARP 337
>gi|162287219 prune homolog 2 [Homo sapiens]
Length = 3088
Score = 60.5 bits (145), Expect = 3e-09
Identities = 32/130 (24%), Positives = 62/130 (47%)
Query: 367 MDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYF 426
M+ LY I ++ + ++Y++VY + T ++KK Y ++D + ++NLK+
Sbjct: 2939 MENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFII 2998
Query: 427 VHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYDARVRST 486
VHP++ + F S KI +V+SL +L I + I P +++ D +R
Sbjct: 2999 VHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLDEELREA 3058
Query: 487 RSSPSPGMVY 496
+ +Y
Sbjct: 3059 SEAAKTSCLY 3068
>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
sapiens]
Length = 464
Score = 58.9 bits (141), Expect = 1e-08
Identities = 51/197 (25%), Positives = 79/197 (40%), Gaps = 32/197 (16%)
Query: 328 SEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTL-IDMDKALLYFIHVMDHIAVKEY 386
S D+A L G D GR V+ +P + +D + L Y + +D +Y
Sbjct: 11 SHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDY 70
Query: 387 VLVYFH---------------TLTSEYNHLDSDF-----------LKK-----LYDVVDV 415
+VYFH + E++ D D LK+ L D
Sbjct: 71 TIVYFHYGLNSRNKPSLGWLQSAYKEFDRKDGDLTMWPRLVSNSKLKRSSHLSLPKYWDY 130
Query: 416 KYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPF 475
+YK+NLKA+Y VHPT KV K+ + + L +L + +Q+ PP
Sbjct: 131 RYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPE 190
Query: 476 VLEYDARVRSTRSSPSP 492
VL YD +++S +P
Sbjct: 191 VLRYDEKLQSLHEGRTP 207
>gi|168480080 BCL2/adenovirus E1B 19kD interacting protein 2 [Homo
sapiens]
Length = 435
Score = 55.5 bits (132), Expect = 1e-07
Identities = 29/124 (23%), Positives = 57/124 (45%)
Query: 367 MDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYF 426
MD Y I ++ + + Y++VY + T+ +L+K Y +D + ++NLK++
Sbjct: 308 MDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMPSLGWLRKCYQQIDRRLRKNLKSLII 367
Query: 427 VHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYDARVRST 486
VHP++ + F S KI +V +L +L + E + P + + D +
Sbjct: 368 VHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQVDQELNGK 427
Query: 487 RSSP 490
+ P
Sbjct: 428 QDEP 431
>gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens]
Length = 369
Score = 55.5 bits (132), Expect = 1e-07
Identities = 46/185 (24%), Positives = 84/185 (45%), Gaps = 13/185 (7%)
Query: 32 TTAEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFM 91
T A+ F + +S FL K+ + + D+A ++ A+V+ +N V ++
Sbjct: 178 TPADGFTVLSTKSLFL-----GQKLQVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEK 232
Query: 92 LAGPDLKE---DLQKLKG-CRTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYS 147
G + E +L+K G A ++ G L A+F+IH P + + E L
Sbjct: 233 KGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGA---DKCEELLEK 289
Query: 148 CYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRR-FLEIHGETIEKVVFA 206
+N L LA ++ + S+ F I S + G+P + A + L+ + F+ +I+ V F
Sbjct: 290 TVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFV 349
Query: 207 VSDLE 211
+ D E
Sbjct: 350 LFDSE 354
>gi|4758496 H2A histone family, member Y isoform 2 [Homo sapiens]
Length = 371
Score = 53.9 bits (128), Expect = 3e-07
Identities = 38/147 (25%), Positives = 69/147 (46%), Gaps = 8/147 (5%)
Query: 70 AIVNTSNESLTDKNPVSESIFMLAGPDLKE---DLQKLKG-CRTGEAKLTKGFNLAARFI 125
AI+N +N + K+ + ++ G + E +L+K G A ++ G L A+F+
Sbjct: 213 AIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFV 272
Query: 126 IHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIA 185
IH P + + E L +N L LA ++ + S+ F I S + G+P + A +
Sbjct: 273 IHCNSPVWGA---DKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLI 329
Query: 186 LRTVRR-FLEIHGETIEKVVFAVSDLE 211
L+ + F+ +I+ V F + D E
Sbjct: 330 LKAISSYFVSTMSSSIKTVYFVLFDSE 356
>gi|93141020 H2A histone family, member Y isoform 2 [Homo sapiens]
Length = 371
Score = 53.9 bits (128), Expect = 3e-07
Identities = 38/147 (25%), Positives = 69/147 (46%), Gaps = 8/147 (5%)
Query: 70 AIVNTSNESLTDKNPVSESIFMLAGPDLKE---DLQKLKG-CRTGEAKLTKGFNLAARFI 125
AI+N +N + K+ + ++ G + E +L+K G A ++ G L A+F+
Sbjct: 213 AIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFV 272
Query: 126 IHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIA 185
IH P + + E L +N L LA ++ + S+ F I S + G+P + A +
Sbjct: 273 IHCNSPVWGA---DKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLI 329
Query: 186 LRTVRR-FLEIHGETIEKVVFAVSDLE 211
L+ + F+ +I+ V F + D E
Sbjct: 330 LKAISSYFVSTMSSSIKTVYFVLFDSE 356
>gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens]
Length = 372
Score = 53.9 bits (128), Expect = 3e-07
Identities = 38/147 (25%), Positives = 69/147 (46%), Gaps = 8/147 (5%)
Query: 70 AIVNTSNESLTDKNPVSESIFMLAGPDLKE---DLQKLKG-CRTGEAKLTKGFNLAARFI 125
AI+N +N + K+ + ++ G + E +L+K G A ++ G L A+F+
Sbjct: 214 AIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFV 273
Query: 126 IHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIA 185
IH P + + E L +N L LA ++ + S+ F I S + G+P + A +
Sbjct: 274 IHCNSPVWGA---DKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLI 330
Query: 186 LRTVRR-FLEIHGETIEKVVFAVSDLE 211
L+ + F+ +I+ V F + D E
Sbjct: 331 LKAISSYFVSTMSSSIKTVYFVLFDSE 357
>gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Homo
sapiens]
Length = 1801
Score = 52.0 bits (123), Expect = 1e-06
Identities = 36/127 (28%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
Query: 56 VVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKED---LQKLKG-CRTGE 111
+++ +GD+A L +VN SNE L ++ ++ AGP+L+ D + K +G G
Sbjct: 804 LIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGN 863
Query: 112 AKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINS 171
A ++K L +IH VGP++ L + L LA++ S+ I+S
Sbjct: 864 ATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISS 923
Query: 172 AKRGYPL 178
G+PL
Sbjct: 924 GVFGFPL 930
Score = 50.8 bits (120), Expect = 3e-06
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 5/142 (3%)
Query: 55 KVVLWKGDVALLNCTAIVNTSNESLT-DKNPVSESIFMLAGPDLKEDLQKLK---GCRTG 110
+++L K V +VN+ L + P+S+S+ AGP+L+E+L + G
Sbjct: 1015 QMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMG 1074
Query: 111 EAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVIN 170
T +NL R+++H V P++++ T++ + R +++ + S+ S+ F I
Sbjct: 1075 TVLKTSSWNLDCRYVLHVVAPEWRNG-STSSLKIMEDIIRECMEITESLSLKSIAFPAIG 1133
Query: 171 SAKRGYPLEDATHIALRTVRRF 192
+ G+P + + V +F
Sbjct: 1134 TGNLGFPKNIFAELIISEVFKF 1155
Score = 35.0 bits (79), Expect = 0.16
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 11/104 (10%)
Query: 61 GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
GD+ IVN+++ S K VS++I AG +++ + + R + +T G L
Sbjct: 1234 GDITKEEADVIVNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYIITGGGFL 1293
Query: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSV 164
+ IIH +G + + S +VLQ ++++ SS+
Sbjct: 1294 RCKNIIHVIG-----------GNDVKSSVSSVLQECEKKNYSSI 1326
>gi|228008343 BCL2/adenovirus E1B 19kD interacting protein like
isoform b [Homo sapiens]
Length = 275
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/122 (26%), Positives = 57/122 (46%)
Query: 359 NIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYK 418
+IP M+ Y + ++ + + Y+LV+ TS ++++ Y +D + +
Sbjct: 145 SIPNYTYVMEHLFRYMVGTLELLVAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLR 204
Query: 419 RNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLE 478
+NL+A+ VH T+ K F S KI +DSL +L IS +Q+ P V +
Sbjct: 205 KNLRALVVVHATWYVKAFLALLRPFISSKFTRKIRFLDSLGELAQLISLDQVHIPEAVRQ 264
Query: 479 YD 480
D
Sbjct: 265 LD 266
>gi|109715844 BCL2/adenovirus E1B 19kD interacting protein like
isoform a [Homo sapiens]
Length = 357
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/122 (26%), Positives = 57/122 (46%)
Query: 359 NIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYK 418
+IP M+ Y + ++ + + Y+LV+ TS ++++ Y +D + +
Sbjct: 227 SIPNYTYVMEHLFRYMVGTLELLVAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLR 286
Query: 419 RNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLE 478
+NL+A+ VH T+ K F S KI +DSL +L IS +Q+ P V +
Sbjct: 287 KNLRALVVVHATWYVKAFLALLRPFISSKFTRKIRFLDSLGELAQLISLDQVHIPEAVRQ 346
Query: 479 YD 480
D
Sbjct: 347 LD 348
>gi|8923920 H2A histone family, member Y2 [Homo sapiens]
Length = 372
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/154 (21%), Positives = 71/154 (46%), Gaps = 8/154 (5%)
Query: 63 VALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCR----TGEAKLTKGF 118
+ + IV+ + + K + +++ G + E +++L+ + EA +++
Sbjct: 207 IGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKEFLETVKELRKSQGPLEVAEAAVSQSS 266
Query: 119 NLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPL 178
LAA+F+IH P++ S E L +N L A+++ + SV F S + +P
Sbjct: 267 GLAAKFVIHCHIPQWGS---DKCEEQLEETIKNCLSAAEDKKLKSVAFPPFPSGRNCFPK 323
Query: 179 EDATHIALRTV-RRFLEIHGETIEKVVFAVSDLE 211
+ A + L+ + F + +++ V F + D E
Sbjct: 324 QTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSE 357
>gi|226371718 poly (ADP-ribose) polymerase family, member 9 isoform
c [Homo sapiens]
Length = 710
Score = 47.8 bits (112), Expect = 2e-05
Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Query: 24 QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81
Q++ T QE +S ++ K + ++ L WK D+ A+VN +NE L
Sbjct: 51 QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 110
Query: 82 KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137
++ ++ G +++E+ ++ GE +T L + IIH VGP++
Sbjct: 111 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 170
Query: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194
+ L ++L + K + +V ++S +PL T + T+R L+
Sbjct: 171 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 229
Score = 46.6 bits (109), Expect = 5e-05
Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)
Query: 34 AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93
+E+ QE T + ++ ++V +G + IVN+ N PV++SI A
Sbjct: 264 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 321
Query: 94 GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150
G ++K + K + ++L TKGFNL ++I H + + S + L +
Sbjct: 322 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 376
Query: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207
L+ EQ+++S+ F + + E A I V F + H + T++ V+F
Sbjct: 377 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 436
Query: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232
E K+L L P+S +EE R
Sbjct: 437 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 471
>gi|226371716 poly (ADP-ribose) polymerase family, member 9 isoform
b [Homo sapiens]
Length = 819
Score = 47.8 bits (112), Expect = 2e-05
Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Query: 24 QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81
Q++ T QE +S ++ K + ++ L WK D+ A+VN +NE L
Sbjct: 51 QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 110
Query: 82 KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137
++ ++ G +++E+ ++ GE +T L + IIH VGP++
Sbjct: 111 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 170
Query: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194
+ L ++L + K + +V ++S +PL T + T+R L+
Sbjct: 171 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 229
Score = 46.6 bits (109), Expect = 5e-05
Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)
Query: 34 AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93
+E+ QE T + ++ ++V +G + IVN+ N PV++SI A
Sbjct: 264 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 321
Query: 94 GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150
G ++K + K + ++L TKGFNL ++I H + + S + L +
Sbjct: 322 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 376
Query: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207
L+ EQ+++S+ F + + E A I V F + H + T++ V+F
Sbjct: 377 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 436
Query: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232
E K+L L P+S +EE R
Sbjct: 437 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 471
>gi|226371714 poly (ADP-ribose) polymerase family, member 9 isoform
b [Homo sapiens]
Length = 819
Score = 47.8 bits (112), Expect = 2e-05
Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Query: 24 QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81
Q++ T QE +S ++ K + ++ L WK D+ A+VN +NE L
Sbjct: 51 QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 110
Query: 82 KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137
++ ++ G +++E+ ++ GE +T L + IIH VGP++
Sbjct: 111 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 170
Query: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194
+ L ++L + K + +V ++S +PL T + T+R L+
Sbjct: 171 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 229
Score = 46.6 bits (109), Expect = 5e-05
Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)
Query: 34 AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93
+E+ QE T + ++ ++V +G + IVN+ N PV++SI A
Sbjct: 264 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 321
Query: 94 GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150
G ++K + K + ++L TKGFNL ++I H + + S + L +
Sbjct: 322 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 376
Query: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207
L+ EQ+++S+ F + + E A I V F + H + T++ V+F
Sbjct: 377 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 436
Query: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232
E K+L L P+S +EE R
Sbjct: 437 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 471
>gi|226371712 poly (ADP-ribose) polymerase family, member 9 isoform
b [Homo sapiens]
Length = 819
Score = 47.8 bits (112), Expect = 2e-05
Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Query: 24 QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81
Q++ T QE +S ++ K + ++ L WK D+ A+VN +NE L
Sbjct: 51 QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 110
Query: 82 KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137
++ ++ G +++E+ ++ GE +T L + IIH VGP++
Sbjct: 111 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 170
Query: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194
+ L ++L + K + +V ++S +PL T + T+R L+
Sbjct: 171 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 229
Score = 46.6 bits (109), Expect = 5e-05
Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)
Query: 34 AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93
+E+ QE T + ++ ++V +G + IVN+ N PV++SI A
Sbjct: 264 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 321
Query: 94 GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150
G ++K + K + ++L TKGFNL ++I H + + S + L +
Sbjct: 322 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 376
Query: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207
L+ EQ+++S+ F + + E A I V F + H + T++ V+F
Sbjct: 377 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 436
Query: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232
E K+L L P+S +EE R
Sbjct: 437 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 471
>gi|226371710 poly (ADP-ribose) polymerase family, member 9 isoform
a [Homo sapiens]
Length = 854
Score = 47.8 bits (112), Expect = 2e-05
Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Query: 24 QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81
Q++ T QE +S ++ K + ++ L WK D+ A+VN +NE L
Sbjct: 86 QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 145
Query: 82 KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137
++ ++ G +++E+ ++ GE +T L + IIH VGP++
Sbjct: 146 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 205
Query: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194
+ L ++L + K + +V ++S +PL T + T+R L+
Sbjct: 206 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 264
Score = 46.6 bits (109), Expect = 5e-05
Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)
Query: 34 AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93
+E+ QE T + ++ ++V +G + IVN+ N PV++SI A
Sbjct: 299 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 356
Query: 94 GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150
G ++K + K + ++L TKGFNL ++I H + + S + L +
Sbjct: 357 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 411
Query: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207
L+ EQ+++S+ F + + E A I V F + H + T++ V+F
Sbjct: 412 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 471
Query: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232
E K+L L P+S +EE R
Sbjct: 472 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 506
>gi|226371706 poly (ADP-ribose) polymerase family, member 9 isoform
a [Homo sapiens]
Length = 854
Score = 47.8 bits (112), Expect = 2e-05
Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Query: 24 QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81
Q++ T QE +S ++ K + ++ L WK D+ A+VN +NE L
Sbjct: 86 QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 145
Query: 82 KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137
++ ++ G +++E+ ++ GE +T L + IIH VGP++
Sbjct: 146 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 205
Query: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194
+ L ++L + K + +V ++S +PL T + T+R L+
Sbjct: 206 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 264
Score = 46.6 bits (109), Expect = 5e-05
Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)
Query: 34 AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93
+E+ QE T + ++ ++V +G + IVN+ N PV++SI A
Sbjct: 299 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 356
Query: 94 GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150
G ++K + K + ++L TKGFNL ++I H + + S + L +
Sbjct: 357 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 411
Query: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207
L+ EQ+++S+ F + + E A I V F + H + T++ V+F
Sbjct: 412 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 471
Query: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232
E K+L L P+S +EE R
Sbjct: 472 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 506
>gi|109826564 neurofibromin isoform 1 [Homo sapiens]
Length = 2839
Score = 40.4 bits (93), Expect = 0.004
Identities = 39/159 (24%), Positives = 62/159 (38%), Gaps = 5/159 (3%)
Query: 329 EDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVL 388
E+ + +L YQ G G + V R I+ D + + + + K Y +
Sbjct: 1582 EEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEI 1641
Query: 389 VYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGL 448
V T T N +DFL K + V N+ AVY + + T + ++GL
Sbjct: 1642 VVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERL-LTGL 1700
Query: 449 K--DKIHHVDSLHQLFSAISPEQIDFP--PFVLEYDARV 483
K ++ +D +L I EQ P LE D +V
Sbjct: 1701 KGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKV 1739
>gi|4557793 neurofibromin isoform 2 [Homo sapiens]
Length = 2818
Score = 40.4 bits (93), Expect = 0.004
Identities = 39/159 (24%), Positives = 62/159 (38%), Gaps = 5/159 (3%)
Query: 329 EDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVL 388
E+ + +L YQ G G + V R I+ D + + + + K Y +
Sbjct: 1561 EEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEI 1620
Query: 389 VYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGL 448
V T T N +DFL K + V N+ AVY + + T + ++GL
Sbjct: 1621 VVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERL-LTGL 1679
Query: 449 K--DKIHHVDSLHQLFSAISPEQIDFP--PFVLEYDARV 483
K ++ +D +L I EQ P LE D +V
Sbjct: 1680 KGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKV 1718
>gi|165377137 poly (ADP-ribose) polymerase family, member 15 isoform
1 [Homo sapiens]
Length = 678
Score = 38.5 bits (88), Expect = 0.014
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 5/124 (4%)
Query: 58 LWKGDVALLNCTAIVNTSNESLT-DKNPVSESIFMLAGPDLKEDLQKLKGC---RTGEAK 113
L GDV + IVN+ +L P+S + AGP L+++L + + G
Sbjct: 93 LISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRRRETEEKVGNIF 152
Query: 114 LTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAK 173
+T G NL + ++H V P + + T+ + + + + L + S SS+ F +I +
Sbjct: 153 MTSGCNLDCKAVLHAVAPYWNNGAETSWQ-IMANIIKKCLTTVEVLSFSSITFPMIGTGS 211
Query: 174 RGYP 177
+P
Sbjct: 212 LQFP 215
Score = 31.6 bits (70), Expect = 1.7
Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 11/115 (9%)
Query: 61 GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
GD+A IVN++ + K+ VS +I AG ++ + L + +T G L
Sbjct: 311 GDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCL 370
Query: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRG 175
+ IIH G K + +VL+ +++ +SV I + G
Sbjct: 371 KCKIIIHVPGGK-----------DVRKTVTSVLEECEQRKYTSVSLPAIGTGNAG 414
>gi|4506541 retinaldehyde binding protein 1 [Homo sapiens]
Length = 317
Score = 33.1 bits (74), Expect = 0.60
Identities = 33/155 (21%), Positives = 61/155 (39%), Gaps = 25/155 (16%)
Query: 346 DNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYN------ 399
D GR VM+ N I D+ L + +++ + E + + +
Sbjct: 152 DKYGRVVMLFNIENWQSQEITFDEILQAYCFILEKLLENEETQINGFCIIENFKGFTMQQ 211
Query: 400 --HLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTT-------FSVSGLKD 450
L + L+K+ D++ + KA++F+H W+FTT F S L +
Sbjct: 212 AASLRTSDLRKMVDMLQDSFPARFKAIHFIH-------QPWYFTTTYNVVKPFLKSKLLE 264
Query: 451 KIH-HVDSLHQLFSAISPEQI--DFPPFVLEYDAR 482
++ H D L + I + DF + +YD +
Sbjct: 265 RVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGK 299
>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
Length = 888
Score = 32.0 bits (71), Expect = 1.3
Identities = 34/130 (26%), Positives = 60/130 (46%), Gaps = 12/130 (9%)
Query: 207 VSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPADIGNAEGEPVVPERQIR-ISEKPGAPE 265
VS+ ++ ++ PL S++E N Y D + + P V +R+ R S+K G+
Sbjct: 177 VSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSED--DNDWRPTVVKRKGRSASQKEGSDG 234
Query: 266 DNQEEEDEGLGVDLSFIG-----SHAFARMEGDIDKQRKLILQGQLSEAALQKQHQRNYN 320
DN+++EDEG G D H+ EG K++ + LS + + N +
Sbjct: 235 DNEDDEDEGSGSDEDENDEGNDEDHSSPASEGGCKKKKSKV----LSRNSADDEELTNDS 290
Query: 321 RWLCQARSED 330
L Q++S +
Sbjct: 291 LTLSQSKSNE 300
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,352,468
Number of Sequences: 37866
Number of extensions: 802760
Number of successful extensions: 2618
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 2560
Number of HSP's gapped (non-prelim): 67
length of query: 496
length of database: 18,247,518
effective HSP length: 106
effective length of query: 390
effective length of database: 14,233,722
effective search space: 5551151580
effective search space used: 5551151580
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.