Guide to the Human Genome
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Search of human proteins with 20665034

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20665034 tenascin XB isoform 2 [Homo sapiens]
         (673 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20665034 tenascin XB isoform 2 [Homo sapiens]                     1388   0.0  
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]          1388   0.0  
gi|153946395 tenascin C precursor [Homo sapiens]                      521   e-147
gi|157384973 tenascin R [Homo sapiens]                                466   e-131
gi|62988324 tenascin N [Homo sapiens]                                 384   e-106
gi|8051586 ficolin 2 isoform b precursor [Homo sapiens]               197   3e-50
gi|61744445 ficolin 2 isoform a precursor [Homo sapiens]              197   3e-50
gi|8051584 ficolin 1 precursor [Homo sapiens]                         191   2e-48
gi|223029463 fibrinogen C domain containing 1 [Homo sapiens]          188   2e-47
gi|223029461 fibrinogen C domain containing 1 [Homo sapiens]          188   2e-47
gi|20532340 angiopoietin 1 [Homo sapiens]                             177   4e-44
gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens]              176   8e-44
gi|23111005 microfibrillar-associated protein 4 [Homo sapiens]        174   2e-43
gi|27754776 ficolin 3 isoform 1 precursor [Homo sapiens]              174   2e-43
gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]               172   7e-43
gi|7705276 angiopoietin 4 [Homo sapiens]                              171   3e-42
gi|169646754 angiopoietin 2 isoform c precursor [Homo sapiens]        168   2e-41
gi|169646749 angiopoietin 2 isoform b precursor [Homo sapiens]        168   2e-41
gi|4557315 angiopoietin 2 isoform a precursor [Homo sapiens]          168   2e-41
gi|4757752 angiopoietin-like 1 precursor [Homo sapiens]               167   3e-41
gi|10863949 angiopoietin-like 7 [Homo sapiens]                        164   2e-40
gi|29893555 angiopoietin-like 6 [Homo sapiens]                        161   2e-39
gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E preprop...   160   5e-39
gi|42544202 fibrinogen-like 1 precursor [Homo sapiens]                158   1e-38
gi|42544200 fibrinogen-like 1 precursor [Homo sapiens]                158   1e-38
gi|42544198 fibrinogen-like 1 precursor [Homo sapiens]                158   1e-38
gi|42544189 fibrinogen-like 1 precursor [Homo sapiens]                158   1e-38
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]      148   2e-35
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]      148   2e-35
gi|5730075 fibrinogen-like 2 precursor [Homo sapiens]                 148   2e-35

>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
          Length = 673

 Score = 1388 bits (3593), Expect = 0.0
 Identities = 673/673 (100%), Positives = 673/673 (100%)

Query: 1   MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
           MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK
Sbjct: 1   MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60

Query: 61  RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
           RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV
Sbjct: 61  RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120

Query: 121 PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
           PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART
Sbjct: 121 PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180

Query: 181 LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK 240
           LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK
Sbjct: 181 LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK 240

Query: 241 LQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNP 300
           LQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNP
Sbjct: 241 LQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNP 300

Query: 301 VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT 360
           VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT
Sbjct: 301 VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT 360

Query: 361 GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGL 420
           GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGL
Sbjct: 361 GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGL 420

Query: 421 FPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGN 480
           FPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGN
Sbjct: 421 FPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGN 480

Query: 481 RERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLT 540
           RERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLT
Sbjct: 481 RERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLT 540

Query: 541 QAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSAR 600
           QAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSAR
Sbjct: 541 QAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSAR 600

Query: 601 DRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMK 660
           DRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMK
Sbjct: 601 DRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMK 660

Query: 661 LRPRNFRSPAGGG 673
           LRPRNFRSPAGGG
Sbjct: 661 LRPRNFRSPAGGG 673


>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
          Length = 4242

 Score = 1388 bits (3593), Expect = 0.0
 Identities = 673/673 (100%), Positives = 673/673 (100%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK
Sbjct: 3570 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 3629

Query: 61   RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
            RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV
Sbjct: 3630 RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 3689

Query: 121  PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
            PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART
Sbjct: 3690 PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 3749

Query: 181  LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK 240
            LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK
Sbjct: 3750 LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK 3809

Query: 241  LQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNP 300
            LQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNP
Sbjct: 3810 LQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNP 3869

Query: 301  VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT 360
            VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT
Sbjct: 3870 VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT 3929

Query: 361  GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGL 420
            GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGL
Sbjct: 3930 GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGL 3989

Query: 421  FPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGN 480
            FPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGN
Sbjct: 3990 FPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGN 4049

Query: 481  RERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLT 540
            RERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLT
Sbjct: 4050 RERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLT 4109

Query: 541  QAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSAR 600
            QAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSAR
Sbjct: 4110 QAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSAR 4169

Query: 601  DRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMK 660
            DRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMK
Sbjct: 4170 DRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMK 4229

Query: 661  LRPRNFRSPAGGG 673
            LRPRNFRSPAGGG
Sbjct: 4230 LRPRNFRSPAGGG 4242



 Score =  232 bits (592), Expect = 7e-61
 Identities = 172/527 (32%), Positives = 249/527 (47%), Gaps = 50/527 (9%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            +RLSW+VAQGPFDSFVVQY DT+GQP+A+ V  DQ  + +  LEP   Y+FLLYGL  GK
Sbjct: 3463 LRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGK 3522

Query: 61   RLGPLSAEGTTG---------LAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAF 111
            RLGP+SA G T          LAP      E  PRL  L+VTD T  S+RL+W    G F
Sbjct: 3523 RLGPVSALGMTAPEEDTPAPELAPEAPEPPE-EPRLGVLTVTDTTPDSMRLSWSVAQGPF 3581

Query: 112  DSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLR----- 166
            DSF++++        + + +P   + L+V G +   ++  L   T Y   LYGL      
Sbjct: 3582 DSFVVQYE-------DTNGQP---QALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRL 3631

Query: 167  GPHKADSIQGTARTLSPVLES-PR--DLQFSEIRETSAKVNWMPPPSRADSFKVSYQLAD 223
            GP  A+   G A       ES PR   L  +++  +S ++NW  PP   DSF + + +  
Sbjct: 3632 GPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPS 3691

Query: 224  GG--EP-------QSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTG---FLT 271
                EP       + + V G   +  L+ L  G  Y +T+  +RG  +++ + G    L+
Sbjct: 3692 PSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLS 3751

Query: 272  TVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQV-TAPGAPPLQAETPGSAVDYPLH 330
             V + P  L+   + E  A ++W PP +  D++ V    A G  P   +  G A    L 
Sbjct: 3752 PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQ 3811

Query: 331  DLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPA 390
             L+    Y  TV  +RG   + P +   TT  + P  L A  +T   A+L W +PP  P 
Sbjct: 3812 GLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHW-KPPQNPV 3870

Query: 391  G-YLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTG 449
              Y +    PG    +   PG    + L  L   T+Y A ++ + G +L  P S +FTTG
Sbjct: 3871 DTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTG 3930

Query: 450  GLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGG 496
               +  PRD    ++      RT+ +       RP        T GG
Sbjct: 3931 ---LEAPRD----LEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGG 3970



 Score =  195 bits (496), Expect = 1e-49
 Identities = 145/501 (28%), Positives = 220/501 (43%), Gaps = 54/501 (10%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            + LSW++ QG FDSF VQY+D +G+PQ + V G++S++ + GLEP   Y+  LYGLHEG+
Sbjct: 2966 LSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQ 3025

Query: 61   RLGPLSAEGTTGLAPAGQTSEES---------RPRLSQLSVTDVTTSSLRLNWEAPPGAF 111
            R+GP+SA G T      +T++           +PRL +L+VTD T  SL L+W  P G F
Sbjct: 3026 RVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQF 3085

Query: 112  DSFLLRF--GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPH 169
            D FL+++  G   P            + + VPG      +  L     Y + LYG  G  
Sbjct: 3086 DHFLVQYRNGDGQP------------KAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 3133

Query: 170  KADSIQGTA----RTLSP------VLESPRDLQFSEIRET-----SAKVNWMPPPSRADS 214
            +   +         T SP        E+P +    E+  T     S  ++W  P  R DS
Sbjct: 3134 RVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDS 3193

Query: 215  FKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVP 274
            F V Y+  D G+PQ V+V G+     + GL PG +Y++ +  +   +   P++    T P
Sbjct: 3194 FTVQYKDRD-GQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAP 3252

Query: 275  DGPT---------QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAV 325
              PT         +L    +T     L W   Q P D++ VQ       P      G   
Sbjct: 3253 -LPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLR 3311

Query: 326  DYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLE---APR--DLEAKEVTPRTALL 380
               +  L     Y   + GL+      P  +   T  +   +PR  +L   + TP +  L
Sbjct: 3312 AVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGL 3371

Query: 381  TWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLP 440
            +WT P      +++ +    G+ Q + +        + GL PS  Y   L  + G+  L 
Sbjct: 3372 SWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLG 3431

Query: 441  PVSTSFTTGGLRIPFPRDCGE 461
            P+S   TT  L    P   GE
Sbjct: 3432 PISADSTTAPLEKELPPHLGE 3452



 Score =  191 bits (485), Expect = 2e-48
 Identities = 145/476 (30%), Positives = 216/476 (45%), Gaps = 41/476 (8%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            + LSW+V QG FDSF VQY+D +GQPQ + V G++S++ + GLEP   Y+  LYGLHEG+
Sbjct: 3180 LSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQ 3239

Query: 61   RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
            R+GP+S  G T   P   T     PRL +L+V  VT+ S+ L+W    G FDSFL+++  
Sbjct: 3240 RVGPVSTVGITAPLP---TPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQY-- 3294

Query: 121  PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
               +  +P   P       V G   +  +  L     Y   L+GL+   +   +   ART
Sbjct: 3295 -RDAQGQPQAVP-------VSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEART 3346

Query: 181  LSPVLESPR--DLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQART 238
                  SPR  +L  ++    S  ++W  P    DSF V Y+  D G  Q V V    R 
Sbjct: 3347 APDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKD-GRLQVVPVAANQRE 3405

Query: 239  QKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVP---DGPTQLRALNLTEGFAV---L 292
              +QGL P  +Y   +  + G +   P++   TT P   + P  L  L + E  +    L
Sbjct: 3406 VTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRL 3465

Query: 293  HWKPPQNPVDTYDVQVT----APGAPPLQAE---------TPGSAVDYPLHDLVLHTNY- 338
             W   Q P D++ VQ       P A P+ A+          PG    + L+ L+      
Sbjct: 3466 SWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLG 3525

Query: 339  TATVRGLRGPNLTSPASITFTTGLEAPRD-----LEAKEVTPRTALLTWTEPPVRPAGYL 393
              +  G+  P   +PA        E P +     L   + TP +  L+W+        ++
Sbjct: 3526 PVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFV 3585

Query: 394  LSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTG 449
            + +    GQ Q +L+ G  +   + GL PST Y   L  +     L P+S   TTG
Sbjct: 3586 VQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTG 3641



 Score =  184 bits (468), Expect = 2e-46
 Identities = 155/528 (29%), Positives = 215/528 (40%), Gaps = 83/528 (15%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            + LSW+V QG FDSF VQY+D +G+PQA+ V G +SK+ + GLEP   Y+  LYGLHEG+
Sbjct: 2538 LSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGR 2597

Query: 61   RLGPLSAEG-------TTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDS 113
            RLGP+SA G       TT   P        +PRL +L++TD T  SL L+W  P G FD 
Sbjct: 2598 RLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDH 2657

Query: 114  FLLRF--GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171
            FL+++  G   P            + + VPG      +  L     Y + LYG  G  + 
Sbjct: 2658 FLVQYRNGDGQP------------KAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRV 2705

Query: 172  DSIQ------GTARTLSP------VLESPRDLQFSEIRET-----SAKVNWMPPPSRADS 214
              I           T SP        E P +    E+  T     S  ++W  P    DS
Sbjct: 2706 GPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDS 2765

Query: 215  FKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYE-----------VTVVSVRGF--E 261
            F V Y+  D G PQ ++V G+     + GL PG +Y+           V  VS  G   +
Sbjct: 2766 FTVQYKDRD-GRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTED 2824

Query: 262  ESEPLTGFLTTVPDGPTQLRALNLTEGFAV-----LHWKPPQNPVDTYDVQVTAPGAPPL 316
            E+E      TT P+ P + R   LT   A      L W  P+   D + VQ       P 
Sbjct: 2825 EAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPK 2884

Query: 317  QAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT------------GLEA 364
                PG      +  L     Y   + G  G     P S+   T              EA
Sbjct: 2885 VVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEA 2944

Query: 365  PR--------DLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQ 416
            P         +L     +P +  L+WT P  R   + + +    G+ Q + + G  +   
Sbjct: 2945 PEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVT 3004

Query: 417  LLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQ 464
            + GL P   Y   L  +     + PVS    T       P+D  E  Q
Sbjct: 3005 VGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTA------PKDEAETTQ 3046



 Score =  177 bits (448), Expect = 4e-44
 Identities = 142/516 (27%), Positives = 205/516 (39%), Gaps = 96/516 (18%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            + LSW+V QG FDSF VQY+D +G+PQ + V G++S++ + GLEP   Y+  LYGLHEG+
Sbjct: 2111 LSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGR 2170

Query: 61   RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF-- 118
            R+GP+SA G T        +  ++ RL Q++V D+T+ SL L+W  P G FD FL++F  
Sbjct: 2171 RVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKN 2230

Query: 119  GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA------- 171
            G   P            + + VPG      +  L     Y + LYG  G  +        
Sbjct: 2231 GDGQP------------KAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVG 2278

Query: 172  ------DSIQGTARTLSPVLESPRDLQFSEIRETSA-----KVNWMPPPSRADSFKVSYQ 220
                  D     A T  P  E P   +  E+  T A      ++W  P  + D F V Y+
Sbjct: 2279 LTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYK 2338

Query: 221  LADGGEPQSVQVDGQARTQKLQGLIPGARYE--------------VTVVSVRGFEE---- 262
              D G+P++ +V G      + GL P  +Y+              V+ + V   EE    
Sbjct: 2339 NGD-GQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPS 2397

Query: 263  ------------SEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTA 310
                         EPL G LT     P  L           L W  PQ   D++ VQ   
Sbjct: 2398 PTEPSMEAPEPPEEPLLGELTVTGSSPDSLS----------LSWTVPQGRFDSFTVQYKD 2447

Query: 311  PGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT---------- 360
                P      G   +  +  L     Y   + GL       P S    T          
Sbjct: 2448 RDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETP 2507

Query: 361  -----GLEAP--------RDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL 407
                 G EAP         +L     +P +  L+WT P  R   + + +    G+ Q + 
Sbjct: 2508 SPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVR 2567

Query: 408  LPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVS 443
            + G  +   + GL P   Y   L  +     L PVS
Sbjct: 2568 VGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVS 2603



 Score =  175 bits (443), Expect = 1e-43
 Identities = 148/576 (25%), Positives = 218/576 (37%), Gaps = 87/576 (15%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            + LSW V +G FDSF +QY D +GQ Q + + GD++ I +SGLE    Y   LYG  +GK
Sbjct: 1897 LHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGK 1956

Query: 61   RLGPLSAEGTT-------GLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDS 113
             +GP+  E  T          P        +PRL +L+VTD T  SL L+W  P G FD 
Sbjct: 1957 HVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDH 2016

Query: 114  FLLRF--GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171
            FL+++  G   P            + + VPG      +  L     Y + LYG  G  + 
Sbjct: 2017 FLVQYRNGDGQP------------KAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRM 2064

Query: 172  DSI---------QGTARTLSPVLESPR--------DLQFSEIRETSAKVNWMPPPSRADS 214
              +         + T     P +E+P         +L  +     S  ++W  P  R DS
Sbjct: 2065 GPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDS 2124

Query: 215  FKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTV- 273
            F V Y+  D G PQ V+V G+     + GL PG +Y++ +  +       P++    T  
Sbjct: 2125 FTVQYKDRD-GRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAP 2183

Query: 274  ----PDGPT------QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGS 323
                PD P       Q+   ++T     L W  P+   D + VQ       P     PG 
Sbjct: 2184 EEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGH 2243

Query: 324  AVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAP------------------ 365
                 +  L     Y   + G  G     P S     GL AP                  
Sbjct: 2244 EDGVTISGLEPDHKYKMNLYGFHGGQRVGPVS---AVGLTAPGKDEEMAPASTEPPTPEP 2300

Query: 366  ------RDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLG 419
                   +L   + TP +  L+WT P  +   +L+ +    GQ +   +PG      + G
Sbjct: 2301 PIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISG 2360

Query: 420  LFPSTSYNARLQAMWGQSLLPPVST-SFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLN 478
            L P   Y   L    G   + PVS    T      P P +   E            + + 
Sbjct: 2361 LEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVT 2420

Query: 479  GNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRD 514
            G+    L++          W V Q R D  T  ++D
Sbjct: 2421 GSSPDSLSL---------SWTVPQGRFDSFTVQYKD 2447



 Score =  174 bits (440), Expect = 3e-43
 Identities = 136/491 (27%), Positives = 216/491 (43%), Gaps = 55/491 (11%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            + L W+V QG FDSF VQY+D +G+P+A+ V G +S++ + GLEP   Y+  LYGLHEG+
Sbjct: 1388 LSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQ 1447

Query: 61   RLGPLSAEGTTGLAPAGQ-----TSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFL 115
            R+GP+SA G T  AP  +     T     PRL +L+VTDVT +S+ L+W  P G FDSF+
Sbjct: 1448 RVGPVSAVGVT--APQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFI 1505

Query: 116  LRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQ 175
            +++        +P   P       V   +    + +L     Y + +YGL    +   + 
Sbjct: 1506 VQY---KDKDGQPQVVP-------VAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLS 1555

Query: 176  GTARTL----SPVLESPR--------DLQFSEIRETSAKVNWMPPPSRADSFKVSYQLAD 223
                T     +P  E+ +        +L  ++I   S  ++W  P    DSF V Y+  D
Sbjct: 1556 VVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRD 1615

Query: 224  GGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTV------PDGP 277
             G+PQ V V    R   +  L P  +Y+  +  ++  +   P++    TV      P  P
Sbjct: 1616 -GQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAP 1674

Query: 278  TQLRALNLTE---GFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVL 334
             +L  L +T+       L W  P+   D++ VQ      P +     G      +  L  
Sbjct: 1675 PRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQV-VPVEGHERSVTVTPLDA 1733

Query: 335  HTNYTATVRGLRGPNLTSPASITFT---------TGLEAP------RDLEAKEVTPRTAL 379
               Y   + GL G     P +   T         TG + P       +L+   VT  +  
Sbjct: 1734 GRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVG 1793

Query: 380  LTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLL 439
            L+WT P  +   +++ +    GQ Q + + G +    + GL P+  Y   L  +     +
Sbjct: 1794 LSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRV 1853

Query: 440  PPVSTSFTTGG 450
             P+S    T G
Sbjct: 1854 GPISAVAITAG 1864



 Score =  169 bits (429), Expect = 6e-42
 Identities = 145/520 (27%), Positives = 218/520 (41%), Gaps = 69/520 (13%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            +RLSW+VAQGPFDSF+VQY+D  GQPQA+ V GD++++ + GL+P   Y+  LYGL   +
Sbjct: 1277 LRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQ 1336

Query: 61   RLGPLS----------AEGTTGLAPAGQTSEES--RPRLSQLSVTDVTTSSLRLNWEAPP 108
            R+GP S           + T      G  + ES   P L +L+VT  +  SL L W  P 
Sbjct: 1337 RVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQ 1396

Query: 109  GAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGP 168
            G+FDSF          T++   R    R + V G      +  L  G  Y + LYGL   
Sbjct: 1397 GSFDSF----------TVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEG 1446

Query: 169  HKADSIQGTART------LSPVLESPRDLQFSEIRET-----SAKVNWMPPPSRADSFKV 217
             +   +     T        P  ESP + +  E+  T     S  ++W  P  + DSF V
Sbjct: 1447 QRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIV 1506

Query: 218  SYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGP 277
             Y+  D G+PQ V V    R   +  L P  +Y++ +  +   +   PL+  + T P  P
Sbjct: 1507 QYKDKD-GQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPP 1565

Query: 278  T---------------QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPG 322
                            +L   ++T     L W  P+   D++ VQ       P       
Sbjct: 1566 APATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAA 1625

Query: 323  SAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASI---TFTTGLEAP------RDLEAKEV 373
               +  + DL     Y   + G++     SP S+   T   G  +P       +L   + 
Sbjct: 1626 DQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDP 1685

Query: 374  TPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAM 433
            TP +  L+WT P  +   +++ F    G  Q + + G   S  +  L     Y   L  +
Sbjct: 1686 TPDSLRLSWTVPEGQFDSFVVQFKDKDGP-QVVPVEGHERSVTVTPLDAGRKYRFLLYGL 1744

Query: 434  WGQSLLPPVSTSFT---------TGGLRIPFPRDCGEEMQ 464
             G+    P++   T         TG  R P PR  GEE+Q
Sbjct: 1745 LGKKRHGPLTADGTTEARSAMDDTGTKRPPKPR-LGEELQ 1783



 Score =  169 bits (429), Expect = 6e-42
 Identities = 137/490 (27%), Positives = 210/490 (42%), Gaps = 58/490 (11%)

Query: 3    LSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRL 62
            LSW+V +G FDSF+VQY+D +GQPQ + V  DQ ++ +  LEP   Y+  +YGLH+G+R+
Sbjct: 1492 LSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRM 1551

Query: 63   GPLSAEGTTGLAPAGQTSEESR----PRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118
            GPLS    T   P    +E S+    PRL +L+VTD+T  S+ L+W  P G FDSF++++
Sbjct: 1552 GPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY 1611

Query: 119  GVPSPSTLEPHPRPLL--QRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQG 176
                    +P   P+   QRE+ +P         DL     Y   L+G++   +   +  
Sbjct: 1612 ---KDRDGQPQVVPVAADQREVTIP---------DLEPSRKYKFLLFGIQDGKRRSPVSV 1659

Query: 177  TARTLSPVLESP------RDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSV 230
             A+T++    SP       +L  ++    S +++W  P  + DSF V ++  DG  PQ V
Sbjct: 1660 EAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDG--PQVV 1717

Query: 231  QVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTV------------PDGP- 277
             V+G  R+  +  L  G +Y   +  + G +   PLT   TT             P  P 
Sbjct: 1718 PVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPR 1777

Query: 278  --TQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLH 335
               +L+   +T+    L W  P+   D++ VQ       P      GS  +  +  L   
Sbjct: 1778 LGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPA 1837

Query: 336  TNYTATVRGLRGPNLTSPAS-ITFTTGLE------------APR----DLEAKEVTPRTA 378
              Y   + GL       P S +  T G E            AP     +L  +E T  T 
Sbjct: 1838 HRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTL 1897

Query: 379  LLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSL 438
             L+W         + + +    GQ Q + + G      L GL     Y   L        
Sbjct: 1898 HLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKH 1957

Query: 439  LPPVSTSFTT 448
            + PV     T
Sbjct: 1958 VGPVHVEALT 1967



 Score =  166 bits (421), Expect = 5e-41
 Identities = 134/506 (26%), Positives = 212/506 (41%), Gaps = 75/506 (14%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            + LSW+V +G FD+F+VQY D +G+PQ + V+G +   ++S L+P   YRF L+G+   K
Sbjct: 1175 LHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKK 1234

Query: 61   RLGPLSAEGTTGLAPAGQTSEE-------SRPRLSQLSVTDVTTSSLRLNWEAPPGAFDS 113
            R GPL+A+GTT    A +  EE        +P L +L+VT VT  SLRL+W    G FDS
Sbjct: 1235 RYGPLTADGTT----APERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDS 1290

Query: 114  FLLRFGVPSPSTLEPHPRPLL--QRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171
            F++++     +  +P   P+   + E+ VPG         L     Y + LYGLRG  + 
Sbjct: 1291 FMVQY---KDAQGQPQAVPVAGDENEVTVPG---------LDPDRKYKMNLYGLRGRQRV 1338

Query: 172  DSIQGTARTL---------------SPVLESPRDLQFSEIRET-----SAKVNWMPPPSR 211
                  A+T                +   ESP +    E+  T     S  + W  P   
Sbjct: 1339 GPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGS 1398

Query: 212  ADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLT 271
             DSF V Y+  D G P++V+V G+     + GL PG +Y++ +  +   +   P++    
Sbjct: 1399 FDSFTVQYKDRD-GRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGV 1457

Query: 272  TVP---------DGPT-----QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQ 317
            T P         + P      +L   ++T     L W  P+   D++ VQ       P  
Sbjct: 1458 TAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQV 1517

Query: 318  AETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPR----------- 366
                    +  +++L     Y   + GL       P S+   T    P            
Sbjct: 1518 VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLE 1577

Query: 367  ----DLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFP 422
                +L   ++TP +  L+WT P      +++ +    GQ Q + +        +  L P
Sbjct: 1578 PRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEP 1637

Query: 423  STSYNARLQAMWGQSLLPPVSTSFTT 448
            S  Y   L  +       PVS    T
Sbjct: 1638 SRKYKFLLFGIQDGKRRSPVSVEAKT 1663



 Score =  164 bits (414), Expect = 3e-40
 Identities = 135/497 (27%), Positives = 204/497 (41%), Gaps = 61/497 (12%)

Query: 3    LSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRL 62
            L W+V +G FDSFV+QY+D +GQPQ + V+G Q   +I+ L+P   Y+F+LYG    KR 
Sbjct: 1080 LRWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRH 1139

Query: 63   GPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPS 122
            GPL AE    + P    S  + P L  L VTD T  SL L+W  P G FD+F++++    
Sbjct: 1140 GPLVAEAK--ILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQY---- 1193

Query: 123  PSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLR-----GPHKADSIQGT 177
                    R    + + V G   S V+  L     Y  TL+G+      GP  AD     
Sbjct: 1194 ------RDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAP 1247

Query: 178  ARTLSP----VLESP--RDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQ 231
             R   P     LE P   +L  + +   S +++W       DSF V Y+ A  G+PQ+V 
Sbjct: 1248 ERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQ-GQPQAVP 1306

Query: 232  VDGQARTQKLQGLIPGARYEVTVVSVRG------------------FEESEPLTGFLTTV 273
            V G      + GL P  +Y++ +  +RG                   +E+   T   T  
Sbjct: 1307 VAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEA 1366

Query: 274  PDGPT-----QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYP 328
            P+ P      +L     +     L W  PQ   D++ VQ       P      G   +  
Sbjct: 1367 PESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVT 1426

Query: 329  LHDLVLHTNYTATVRGLR-----GP----NLTSPASITFTTGLEAP-----RDLEAKEVT 374
            +  L     Y   + GL      GP     +T+P         E+P      +L   +VT
Sbjct: 1427 VGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVT 1486

Query: 375  PRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMW 434
            P +  L+WT P  +   +++ +    GQ Q + +        +  L P   Y   +  + 
Sbjct: 1487 PNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLH 1546

Query: 435  GQSLLPPVSTSFTTGGL 451
                + P+S    T  L
Sbjct: 1547 DGQRMGPLSVVIVTAPL 1563



 Score =  163 bits (412), Expect = 5e-40
 Identities = 146/577 (25%), Positives = 226/577 (39%), Gaps = 84/577 (14%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            + LSW+V +G FD F+VQY + +GQP+A+ V G +  + ISGLEP   Y+  LYG H G+
Sbjct: 2003 LSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQ 2062

Query: 61   RLGPLSAEGTTG--------LAPAGQTSEES-RPRLSQLSVTDVTTSSLRLNWEAPPGAF 111
            R+GP+S  G T           P+ +  E +  P L +L+VT  +  SL L+W  P G F
Sbjct: 2063 RMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRF 2122

Query: 112  DSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171
            DSF +++        +   RP + R   V G      +  L  G  Y + LYGL    + 
Sbjct: 2123 DSFTVQY-------KDRDGRPQVVR---VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRV 2172

Query: 172  DSIQGTARTLSPVLESP---------RDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLA 222
              +     T +P  ESP           +   +I   S  ++W  P  + D F V ++  
Sbjct: 2173 GPVSAVGVT-APEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNG 2231

Query: 223  DGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVP-------- 274
            D G+P++V+V G      + GL P  +Y++ +    G +   P++    T P        
Sbjct: 2232 D-GQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAP 2290

Query: 275  ---DGPT----------QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETP 321
               + PT          +L   + T     L W  P+   D + VQ       P     P
Sbjct: 2291 ASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVP 2350

Query: 322  GSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT------------GLEAPR--- 366
            G      +  L     Y   + G  G     P S    T             +EAP    
Sbjct: 2351 GHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPE 2410

Query: 367  -----DLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLF 421
                 +L     +P +  L+WT P  R   + + +    G+ Q + + G  +   + GL 
Sbjct: 2411 EPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLE 2470

Query: 422  PSTSYNARLQAMWGQSLLPPVSTSFTTGGL----RIPFPRDCGEEMQNGAGASRTSTIFL 477
            P   Y   L  +     + PVST   T         P P + G E            + +
Sbjct: 2471 PGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTV 2530

Query: 478  NGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRD 514
             G+    L++          W V Q R D  T  ++D
Sbjct: 2531 TGSSPDSLSL---------SWTVPQGRFDSFTVQYKD 2558



 Score =  159 bits (402), Expect = 8e-39
 Identities = 132/466 (28%), Positives = 193/466 (41%), Gaps = 34/466 (7%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            + LSW V +G FD F+VQY + +GQP+A+ V G +  + ISGLEP   Y+  LYG H G+
Sbjct: 3074 LSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 3133

Query: 61   RLGPLSAEGTT------GLAPAGQTSE-ESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDS 113
            R+GP+SA G T         P+ +  E    P L +L+VT  +  SL L+W  P G FDS
Sbjct: 3134 RVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDS 3193

Query: 114  FLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLR-----GP 168
            F          T++   R    + + V G      +  L  G  Y + LYGL      GP
Sbjct: 3194 F----------TVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGP 3243

Query: 169  HKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQ 228
                 I     T  PV     +L  + +   S  ++W       DSF V Y+ A  G+PQ
Sbjct: 3244 VSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQ-GQPQ 3302

Query: 229  SVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEG 288
            +V V G  R   + GL P  +Y+  +  ++  +   P+     T PD     R   LT  
Sbjct: 3303 AVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVT 3362

Query: 289  FAV-----LHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVR 343
             A      L W  P+   D++ VQ               +  +  +  L     Y   + 
Sbjct: 3363 DATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLY 3422

Query: 344  GLRGPNLTSPASITFTTG---LEAP---RDLEAKEVTPRTALLTWTEPPVRPAGYLLSFH 397
            GL G     P S   TT     E P    +L   E T  +  L+WT        +++ + 
Sbjct: 3423 GLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYR 3482

Query: 398  TPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVS 443
               GQ + + +     +  +  L P   Y   L  + G   L PVS
Sbjct: 3483 DTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVS 3528



 Score =  125 bits (313), Expect = 2e-28
 Identities = 119/488 (24%), Positives = 184/488 (37%), Gaps = 56/488 (11%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQ-PQALLVDGDQSKILISGLEPSTPYRFLLYGLHEG 59
            +R+ W+     F  F ++     G      ++ GD  + L+    P TPY   L+G+  G
Sbjct: 977  LRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPG 1036

Query: 60   -KRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118
             K   P+  +G               PRL +L+VTD T+ SL L W  P G FDSF++++
Sbjct: 1037 GKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQY 1096

Query: 119  GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTA 178
                        R    + + V G + SAV+  L  G  Y   LYG  G  +   +   A
Sbjct: 1097 ----------KDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEA 1146

Query: 179  RTLSPVLESP------RDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQV 232
            + L     SP       +L  ++    S  ++W  P  + D+F V Y+  D G PQ V V
Sbjct: 1147 KILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRD-GRPQVVPV 1205

Query: 233  DGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPT-------------- 278
            +G  R+  +  L P  +Y  T+  +   +   PLT   TT P+                 
Sbjct: 1206 EGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLG 1265

Query: 279  QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNY 338
            +L    +T     L W   Q P D++ VQ       P      G   +  +  L     Y
Sbjct: 1266 ELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKY 1325

Query: 339  TATVRGLRGPNLTSPASITFTT---------------GLEAPR--------DLEAKEVTP 375
               + GLRG     P S+   T               G EAP         +L     +P
Sbjct: 1326 KMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSP 1385

Query: 376  RTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWG 435
             +  L WT P      + + +    G+ + + + G  +   + GL P   Y   L  +  
Sbjct: 1386 DSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHE 1445

Query: 436  QSLLPPVS 443
               + PVS
Sbjct: 1446 GQRVGPVS 1453



 Score =  102 bits (253), Expect = 2e-21
 Identities = 134/577 (23%), Positives = 199/577 (34%), Gaps = 87/577 (15%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            + L W   Q   D FVV Y     Q   L V  +    L++ L P   Y  +      G+
Sbjct: 856  LELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEY-VVTVTAERGR 914

Query: 61   RLG-PLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVT----------------------T 97
             +  P S    TG +P G       P  S  S T                         T
Sbjct: 915  AVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDET 974

Query: 98   SSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTL 157
              LR+ W A P  F  F LR  VP               E ++PG    A++     GT 
Sbjct: 975  GRLRVVWTAQPDTFAYFQLRMRVPEGPG---------AHEEVLPGDVRQALVPPPPPGTP 1025

Query: 158  YSLTLYGL-RGPHKADSI----------QGTARTLSPVLESPR--DLQFSEIRETSAKVN 204
            Y L+L+G+  G   +D I          +   ++  P    PR  +L  ++    S  + 
Sbjct: 1026 YELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGP----PRLGELTVTDRTSDSLLLR 1081

Query: 205  WMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESE 264
            W  P    DSF + Y+  D G+PQ V V+G  R+  +  L PG +Y+  +    G +   
Sbjct: 1082 WTVPEGEFDSFVIQYKDRD-GQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHG 1140

Query: 265  PLTGFLTTVPDG------PTQLRALNLTE---GFAVLHWKPPQNPVDTYDVQVTAPGAPP 315
            PL      +P        P  L  L +T+       L W  P+   DT+ VQ       P
Sbjct: 1141 PLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRP 1200

Query: 316  LQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTG------------LE 363
                  G    + +  L     Y  T+ G+       P +   TT             LE
Sbjct: 1201 QVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLE 1260

Query: 364  AP--RDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLF 421
             P   +L    VTP +  L+WT        +++ +    GQ Q + + G      + GL 
Sbjct: 1261 QPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLD 1320

Query: 422  PSTSYNARLQAMWGQSLLPPVSTSFTTGGL----RIPFPRDCGEEMQNGAGASRTSTIFL 477
            P   Y   L  + G+  + P S    T         P P + G E            + +
Sbjct: 1321 PDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTV 1380

Query: 478  NGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRD 514
             G+    L++F         W V Q   D  T  ++D
Sbjct: 1381 TGSSPDSLSLF---------WTVPQGSFDSFTVQYKD 1408



 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 53/159 (33%), Positives = 71/159 (44%), Gaps = 3/159 (1%)

Query: 294 WKPPQNPVDTYDVQ---VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNL 350
           W P   PVD Y++Q    T   +PP  A  P SA  Y    L     Y  TVR LRG + 
Sbjct: 769 WTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSW 828

Query: 351 TSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPG 410
             PAS T TT ++ P+DL    VTP T  L W  P      +++S+ + G Q   + +P 
Sbjct: 829 GLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPP 888

Query: 411 GITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTG 449
                 L  L P   Y   + A  G+++  P S    TG
Sbjct: 889 EADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTG 927



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 61/198 (30%), Positives = 91/198 (45%), Gaps = 15/198 (7%)

Query: 196 IRETSAKVNWMPPPSRADSFKVSY-QLADGGEPQ-SVQVDGQARTQKLQGLIPGARYEVT 253
           + ET+ +  W P P   D++++ +    +G  P  + +V   A     +GL PG  Y+VT
Sbjct: 760 LEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVT 819

Query: 254 VVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGA 313
           V ++RG     P +  +TT+ DGP  LR + +T     L W  PQ  VD + V   + G 
Sbjct: 820 VRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGN 879

Query: 314 PPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEV 373
             ++ E P  A    L DL+    Y  TV   RG  ++ PAS+   TG            
Sbjct: 880 QRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTG-----------S 928

Query: 374 TPRTALLTWTEPPVRPAG 391
           +P   L T  EPP  P+G
Sbjct: 929 SPLGLLGTTDEPP--PSG 944



 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 96/415 (23%), Positives = 162/415 (39%), Gaps = 61/415 (14%)

Query: 76   AGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQ 135
            AG+   E  P +  + +  +  +++R  W   PG  D++ ++F +P+     P   P   
Sbjct: 741  AGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQF-IPTTEGASP---PFTA 796

Query: 136  RELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSE 195
            R   VP +  +   R L  G  Y +T+  LRG          ++T++ +++ P+DL+   
Sbjct: 797  R---VPSSASAYDQRGLAPGQEYQVTVRALRGTSWG---LPASKTITTMIDGPQDLRVVA 850

Query: 196  IRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVV 255
            +  T+ ++ W+ P +  D F VSY ++ G +   ++V  +A    L  L+PG  Y VTV 
Sbjct: 851  VTPTTLELGWLRPQAEVDRFVVSY-VSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVT 909

Query: 256  SVRGFEESEPLT----------GFLTTV----PDGPT------------------QLRAL 283
            + RG   S P +          G L T     P GP+                  +LR L
Sbjct: 910  AERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVL 969

Query: 284  NLTE-GFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAET-PGSAVDYPLHDLVLHTNYTAT 341
               E G   + W    +    + +++  P  P    E  PG      +      T Y  +
Sbjct: 970  GRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELS 1029

Query: 342  VRGLRGPNLTSPASITFTTGL-----------EAPRDLEAKEVTPRTA---LLTWTEPPV 387
            + G+  P    P+      G+             P  L    VT RT+   LL WT P  
Sbjct: 1030 LHGV--PPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEG 1087

Query: 388  RPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPV 442
                +++ +    GQ Q + + G   S  +  L P   Y   L    G+    P+
Sbjct: 1088 EFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPL 1142



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 108/493 (21%), Positives = 179/493 (36%), Gaps = 57/493 (11%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTN---GQPQALLVDGDQSKILISGLEPSTPYRFLLYGLH 57
            +R  W+ A GP D++ +Q+  T      P    V    S     GL P   Y+  +  L 
Sbjct: 765  VRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALR 824

Query: 58   EGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFL-- 115
                       GT+   PA +T          L V  VT ++L L W  P    D F+  
Sbjct: 825  -----------GTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVS 873

Query: 116  --------LRFGVP--SPSTLEPHPRPLLQRELMVPGTRHSAVL--RDLRSGTLYS-LTL 162
                    +R  VP  +  TL     P ++  + V   R  AV     +R+ T  S L L
Sbjct: 874  YVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGL 933

Query: 163  YGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIR-----ETS-AKVNWMPPPSRADSFK 216
             G            T    +P+L+  R  +  E+R     ET   +V W   P     F+
Sbjct: 934  LGTTDEPPPSGPSTTQGAQAPLLQQ-RPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQ 992

Query: 217  VSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSV-RGFEESEPL--TGFLTTV 273
            +  ++ +G       + G  R   +    PG  YE+++  V  G + S+P+   G +   
Sbjct: 993  LRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKD 1052

Query: 274  PD------GPTQLRALNLTEGFA---VLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSA 324
             +      GP +L  L +T+  +   +L W  P+   D++ +Q       P      G  
Sbjct: 1053 EEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQ 1112

Query: 325  VDYPLHDLVLHTNYTATVRGLRGPN----LTSPASITFTTGLEAPR-----DLEAKEVTP 375
                +  L     Y   + G  G      L + A I   +           +L   + TP
Sbjct: 1113 RSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTP 1172

Query: 376  RTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWG 435
             +  L+WT P  +   +++ +    G+ Q + + G   S  +  L P   Y   L  +  
Sbjct: 1173 DSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIAN 1232

Query: 436  QSLLPPVSTSFTT 448
            +    P++   TT
Sbjct: 1233 KKRYGPLTADGTT 1245


>gi|153946395 tenascin C precursor [Homo sapiens]
          Length = 2201

 Score =  521 bits (1341), Expect = e-147
 Identities = 275/671 (40%), Positives = 387/671 (57%), Gaps = 23/671 (3%)

Query: 3    LSWSVAQGPFDSFVVQYEDTNG--QPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            +SW  ++  FDSF+V   D+     PQ   + G Q K+ + GL     Y  ++ G  +G 
Sbjct: 1547 VSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGH 1606

Query: 61   RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
            +  PL AE  T          E+ P +  L V+D T    RL+W A  G FD+F+L+   
Sbjct: 1607 QTKPLRAEIVT----------EAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRD 1656

Query: 121  PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
                + EP     L+  L+ P    +  +  LR  T Y + LYG+    ++ ++   A T
Sbjct: 1657 TKKQS-EP-----LEITLLAP--ERTRDITGLREATEYEIELYGISKGRRSQTVSAIATT 1708

Query: 181  LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK 240
                + SP+++ FS+I E SA V+W  P ++ +SF+++Y    GG P  V VDG     +
Sbjct: 1709 ---AMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTR 1765

Query: 241  LQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNP 300
            L  LIPG  Y V++++++GFEESEP++G  TT  DGP+ L   N+T+  A+  W+P    
Sbjct: 1766 LVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIAT 1825

Query: 301  VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT 360
            VD+Y +  T    P +     G+ V+Y L DL   T YT  +   +GP  +S  +  FTT
Sbjct: 1826 VDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTT 1885

Query: 361  GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGL 420
             L++PRDL A EV   TALLTW  P     GYLL + +  G  +E+++    TS+ L  L
Sbjct: 1886 DLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADL 1945

Query: 421  FPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGN 480
             PST Y A++QA+ G      + T FTT GL  PFP+DC + M NG   S   TI+LNG+
Sbjct: 1946 SPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNGDTTSGLYTIYLNGD 2005

Query: 481  RERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLT 540
            +   L VFCDM +DGGGW+VF RR +G+ +F+++W+ YA GFG+   EFWLG + L+ +T
Sbjct: 2006 KAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLDNLNKIT 2065

Query: 541  QAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSAR 600
              G Y +RVDLR   E  FA YD F V  A   Y+L +EGY GTAGDSM+YH+G  FS  
Sbjct: 2066 AQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFSTF 2125

Query: 601  DRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMK 660
            D+D +S + +CA+SY+GA+WYRNCH  NL G YG     QGV+W+HWKG E S+ F EMK
Sbjct: 2126 DKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHWKGHEHSIQFAEMK 2185

Query: 661  LRPRNFRSPAG 671
            LRP NFR+  G
Sbjct: 2186 LRPSNFRNLEG 2196



 Score =  150 bits (378), Expect = 5e-36
 Identities = 126/459 (27%), Positives = 206/459 (44%), Gaps = 35/459 (7%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNG--QPQALLVDGDQSKILISGLEPSTPYRFLLYGLHE 58
            +RL+W+ A   ++ FV+Q ++ N     Q L + G    + I GLE +TPYR  +YG+  
Sbjct: 1363 LRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR 1422

Query: 59   GKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118
            G R   LSAE +T             P +  L+V+D+T  S  L+W A  G F++F +  
Sbjct: 1423 GYRTPVLSAEASTA----------KEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEI 1472

Query: 119  GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTA 178
             + S   LE         E  + G   +A +  L   T + + L GL    +  +I  TA
Sbjct: 1473 -IDSNRLLE-------TVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATA 1524

Query: 179  RTLS-PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGG---EPQSVQVDG 234
             T + P+LE   +L  S+I      V+WM   +  DSF V+  + D G   +PQ   + G
Sbjct: 1525 TTEALPLLE---NLTISDINPYGFTVSWMASENAFDSFLVT--VVDSGKLLDPQEFTLSG 1579

Query: 235  QARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTT--VPDGPTQLRALNLTEGFAVL 292
              R  +L+GLI G  YEV V       +++PL   + T   P+    L +    +GF  L
Sbjct: 1580 TQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFR-L 1638

Query: 293  HWKPPQNPVDTYDVQV--TAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNL 350
             W   +   D + +++  T   + PL+           +  L   T Y   + G+     
Sbjct: 1639 SWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRR 1698

Query: 351  TSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSF-HTPGGQNQEILLP 409
            +   S   TT + +P+++   ++T  +A ++W  P  +   + +++    GG    + + 
Sbjct: 1699 SQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVD 1758

Query: 410  GGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 448
            G  T  +L+ L P   Y   + AM G     PVS SFTT
Sbjct: 1759 GTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTT 1797



 Score =  137 bits (345), Expect = 3e-32
 Identities = 112/446 (25%), Positives = 188/446 (42%), Gaps = 38/446 (8%)

Query: 15   FVVQYEDTN--GQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTG 72
            ++V Y  T+  G      V GDQ+  +I  LEP   Y   ++ + E K+  P+SA   T 
Sbjct: 652  YLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATY 711

Query: 73   L-APAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPR 131
            L AP G            L    +  +S+ + W+    AF+++ + F       +     
Sbjct: 712  LPAPEG------------LKFKSIKETSVEVEWDPLDIAFETWEIIF-----RNMNKEDE 754

Query: 132  PLLQRELMVPGTRHSAVLRDLRSGTLYSLTLY----GLRGPHKADSIQGTARTLSPVLES 187
              + + L  P T +      L  G  Y ++L+      RGP       G  R  +  L++
Sbjct: 755  GEITKSLRRPETSYRQT--GLAPGQEYEISLHIVKNNTRGP-------GLKRVTTTRLDA 805

Query: 188  PRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLAD-GGEPQSVQVDGQARTQKLQGLIP 246
            P  ++  ++ +T+A + W  P +  D  +++Y + D  G+  ++ +        +  L P
Sbjct: 806  PSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKP 865

Query: 247  GARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDV 306
               YEV+++S RG   S P     TT  D P  LR ++ T+    L W+  +  +D+Y +
Sbjct: 866  DTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRI 925

Query: 307  QVTA-PGAPPLQAETPGS---AVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGL 362
            +     G    + + P S        L  L   T Y   V  ++    ++PA+I   T L
Sbjct: 926  KYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATEL 985

Query: 363  EAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFP 422
            + P+DL+  E    +  L W  P  +   Y L++  P GQ   + LP   TS+ L GL P
Sbjct: 986  DTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEP 1045

Query: 423  STSYNARLQAMWGQSLLPPVSTSFTT 448
               YN  L A  G+    P     +T
Sbjct: 1046 GQEYNVLLTAEKGRHKSKPARVKAST 1071



 Score =  124 bits (311), Expect = 3e-28
 Identities = 126/482 (26%), Positives = 206/482 (42%), Gaps = 73/482 (15%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQA--LLVDGDQSKILISGLEPSTPYRFLLYGLHE 58
            +RL+W+ A   ++ F++Q ++ N    A  L V G    + I GL+ +TPY   +YG+ +
Sbjct: 1090 LRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQ 1149

Query: 59   GKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118
            G R   LSAE +TG            P L ++ V +V   +L+LNW AP GA++ F ++ 
Sbjct: 1150 GYRTPVLSAEASTG----------ETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQ- 1198

Query: 119  GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTA 178
             V    T+E        + L VPG   S  L  L++ T Y++T+ G+        +  + 
Sbjct: 1199 -VQEADTVE------AAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPL--SV 1249

Query: 179  RTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADG-GEPQSVQVDGQAR 237
              L+  +    +L  +E+   + ++NW  P    D F +  Q AD   E  ++ V G  R
Sbjct: 1250 EVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLR 1309

Query: 238  TQKLQGLIPGARYEVTV-VSVRGFEESEPLTGFLTTVPDGPTQLRALNLTE---GFAVLH 293
            + ++ GL  G  Y VT+   VRG   + PL   +  V +   QL  L ++E       L+
Sbjct: 1310 SMEIPGLRAGTPYTVTLHGEVRG-HSTRPLA--VEVVTEDLPQLGDLAVSEVGWDGLRLN 1366

Query: 294  WKPPQNPVDTYDVQV------------TAPGA------PPLQAETPGSAVDYPLHDLVLH 335
            W    N  + + +QV            T PG+      P L+A TP     Y        
Sbjct: 1367 WTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIY-------- 1418

Query: 336  TNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLS 395
                  +RG R P L++ AS   T       +L   ++TP +  L+W    +   G   +
Sbjct: 1419 ----GVIRGYRTPVLSAEAS---TAKEPEIGNLNVSDITPESFNLSW----MATDGIFET 1467

Query: 396  FHTPGGQNQEIL------LPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTG 449
            F      +  +L      + G   +  + GL PST +   L  +        +S + TT 
Sbjct: 1468 FTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTE 1527

Query: 450  GL 451
             L
Sbjct: 1528 AL 1529



 Score =  109 bits (272), Expect = 9e-24
 Identities = 115/461 (24%), Positives = 187/461 (40%), Gaps = 39/461 (8%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLY---GLH 57
            + L W      FD + + Y    GQ   + +  + +  ++ GLEP   Y  LL    G H
Sbjct: 1001 LTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRH 1060

Query: 58   EGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLR 117
            + K   P   + +T          E  P L  L+VT+V    LRLNW A   A++ F+++
Sbjct: 1061 KSK---PARVKAST----------EQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQ 1107

Query: 118  FGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGT 177
              V   + +E        R L VPG+  +  +  L++ T Y++++YG+   ++   +   
Sbjct: 1108 --VQEANKVE------AARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAE 1159

Query: 178  ARTLSPVLESPR--DLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGE-PQSVQVDG 234
            A T     E+P   ++  +E+   + K+NW  P    + F +  Q AD  E  Q++ V G
Sbjct: 1160 AST----GETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPG 1215

Query: 235  QARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTT--VPDGPTQLRALNLTEGFAVL 292
              R+  L GL     Y +T+  V     + PL+  + T  VPD    L    ++     L
Sbjct: 1216 GLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPD-MGNLTVTEVSWDALRL 1274

Query: 293  HWKPPQNPVDTYDVQVTAPG--APPLQAETPGSAVDYPLHDLVLHTNYTATVRG-LRGPN 349
            +W  P    D + +QV              PGS     +  L   T YT T+ G +RG +
Sbjct: 1275 NWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHS 1334

Query: 350  LTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQN--QEIL 407
                A    T  L    DL   EV      L WT        +++           Q + 
Sbjct: 1335 TRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLT 1394

Query: 408  LPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 448
            LPG + +  + GL  +T Y   +  +      P +S   +T
Sbjct: 1395 LPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEAST 1435



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 68/280 (24%), Positives = 111/280 (39%), Gaps = 31/280 (11%)

Query: 188 PRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPG 247
           P+DL  +E+ E +  + W       +   V     +GG     +V G   +  +Q L PG
Sbjct: 626 PKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPG 685

Query: 248 ARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDV- 306
             Y + V ++   ++S P++  + T    P  L+  ++ E    + W P     +T+++ 
Sbjct: 686 VEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEII 745

Query: 307 ----------QVTAPGAPPLQAE-----TPGSAVDYPLHDLVLHTNYTATVRGLRGPNLT 351
                     ++T     P  +       PG   +  LH +  +T         RGP L 
Sbjct: 746 FRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNT---------RGPGLK 796

Query: 352 SPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPG--GQNQEILLP 409
                  TT L+AP  +E K+VT  TAL+TW +P     G  L++      G    I L 
Sbjct: 797 RVT----TTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLT 852

Query: 410 GGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTG 449
                + +  L P T Y   L +  G     P   +FTTG
Sbjct: 853 EDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTG 892


>gi|157384973 tenascin R [Homo sapiens]
          Length = 1358

 Score =  466 bits (1200), Expect = e-131
 Identities = 248/669 (37%), Positives = 359/669 (53%), Gaps = 22/669 (3%)

Query: 3    LSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRL 62
            L W+ A GP D + + +  ++G    + V  D++   ++ LEP   Y   +      ++ 
Sbjct: 704  LIWTKASGPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQS 763

Query: 63   GPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPS 122
               + +  TG  P           +S L  + VT+SS+ + W  P    D  +L +    
Sbjct: 764  LESTVDAFTGFRP-----------ISHLHFSHVTSSSVNITWSDPSPPADRLILNYS--- 809

Query: 123  PSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLS 182
                 P        E+ +  T+  AVL  L+  T Y + L  + G   ++ I G+  T  
Sbjct: 810  -----PRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITT-- 862

Query: 183  PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQ 242
              ++ P+D+  S + + S  V+W PP +  D ++VSY+    G   S  V        + 
Sbjct: 863  -GIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTIT 921

Query: 243  GLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVD 302
             L P   YE+++ SVRG EESE +   + T  D P  L A N+T   A+L WK P   V+
Sbjct: 922  RLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVE 981

Query: 303  TYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGL 362
             Y + +T            G + ++ L DL+  T+YTAT+    GP  +   S  F+T L
Sbjct: 982  NYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTLL 1041

Query: 363  EAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFP 422
            + P +L A EVT ++AL++W  P      Y+L++ +  G  +E+++    T  +L GL  
Sbjct: 1042 DPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLE 1101

Query: 423  STSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRE 482
            +T Y   LQA    +     ST+FTTGG   P P+DC + + NG   S    IFLNG   
Sbjct: 1102 NTDYTVLLQAAQDTTWSSITSTAFTTGGRVFPHPQDCAQHLMNGDTLSGVYPIFLNGELS 1161

Query: 483  RPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQA 542
            + L V+CDM TDGGGW+VFQRR +GQTDF+R W DY  GFGN+  EFWLG + +H +T  
Sbjct: 1162 QKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGLDNIHRITSQ 1221

Query: 543  GDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDR 602
            G Y +RVD+R G EA FA YD F V+ +   Y+L +  Y+GTAGDS+SYH G  FS  DR
Sbjct: 1222 GRYELRVDMRDGQEAAFASYDRFSVEDSRNLYKLRIGSYNGTAGDSLSYHQGRPFSTEDR 1281

Query: 603  DPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLR 662
            D +  + +CA+SY+GAWWY+NCH  NLNG YG +   QG++WYHWKG EFS+PF EMK+R
Sbjct: 1282 DNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQGINWYHWKGHEFSIPFVEMKMR 1341

Query: 663  PRNFRSPAG 671
            P N R  AG
Sbjct: 1342 PYNHRLMAG 1350



 Score =  121 bits (304), Expect = 2e-27
 Identities = 99/377 (26%), Positives = 164/377 (43%), Gaps = 25/377 (6%)

Query: 90  LSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVL 149
           L V  ++  S+ L W+ P    +  +         + +P     LQ +  VPG      +
Sbjct: 332 LRVAGISDRSIELEWDGPMAVTEYVI---------SYQPTALGGLQLQQRVPGDWSGVTI 382

Query: 150 RDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPP 209
            +L  G  Y++++Y +       S+  TA+  +  L +P+ LQF  I ET+ +V W P  
Sbjct: 383 TELEPGLTYNISVYAVIS--NILSLPITAKVATH-LSTPQGLQFKTITETTVEVQWEPFS 439

Query: 210 SRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGF 269
              D +++S+   +       QV     +    GL PG  Y V VV+++    S P +  
Sbjct: 440 FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499

Query: 270 LTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVD----TYDVQVTAPGAPPLQAETPGSAV 325
           ++TV DGPTQ+   ++++  A + W PP+  VD     Y +     G    + + P S  
Sbjct: 500 VSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLS-- 557

Query: 326 DYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEP 385
            Y +  L   + Y  +V  +RG N +  A+  FTT ++AP++L     T  +  L W   
Sbjct: 558 QYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNS 617

Query: 386 PVRPAGYLLSFHT-PGGQNQEILLPGGI---TSHQLLGLFPSTSYNARLQAMWGQSLLPP 441
                 Y + + T  G Q  E+L+P GI   T   L  L P T Y   + A+       P
Sbjct: 618 EAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVP 677

Query: 442 VSTSFTTGGLRIPFPRD 458
            + +  T    +  PRD
Sbjct: 678 ATMNART---ELDSPRD 691



 Score =  120 bits (301), Expect = 4e-27
 Identities = 111/456 (24%), Positives = 184/456 (40%), Gaps = 30/456 (6%)

Query: 1   MRLSWSVAQGPFDSFVVQYEDTNGQPQALL-VDGDQSKILISGLEPSTPYRFLLYGLHEG 59
           + + W      FD + + +   N +   +  V  D +    +GL+P   Y   +  L E 
Sbjct: 431 VEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQ 490

Query: 60  KRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFG 119
            R  P SA  +T +   G T         Q+ V DV+ +   + W  P    D  LL++G
Sbjct: 491 ARSPPTSASVSTVID--GPT---------QILVRDVSDTVAFVEWIPPRAKVDFILLKYG 539

Query: 120 VPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTAR 179
           +          R      L  P +++S  ++ LR G+ Y +++  +RG +++DS      
Sbjct: 540 LVGGEGGRTTFR------LQPPLSQYS--VQALRPGSRYEVSVSAVRGTNESDS---ATT 588

Query: 180 TLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVD---GQA 236
             +  +++P++L+      TS  + W    +    +KV Y    G +   V V    G  
Sbjct: 589 QFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPT 648

Query: 237 RTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKP 296
               L  L+PG  Y V + +V   ++S P T    T  D P  L     +E    L W  
Sbjct: 649 TRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTK 708

Query: 297 PQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASI 356
              P+D Y +  T       +   P     Y L DL     Y  +V   RG   +  +++
Sbjct: 709 ASGPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTV 768

Query: 357 TFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL---LPGGIT 413
              TG      L    VT  +  +TW++P   PA  L+  ++P  + +E++   L     
Sbjct: 769 DAFTGFRPISHLHFSHVTSSSVNITWSDPS-PPADRLILNYSPRDEEEEMMEVSLDATKR 827

Query: 414 SHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTG 449
              L+GL P+T Y   L A+ G     P+  S TTG
Sbjct: 828 HAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTG 863



 Score =  119 bits (298), Expect = 9e-27
 Identities = 120/458 (26%), Positives = 190/458 (41%), Gaps = 38/458 (8%)

Query: 1   MRLSWSVAQGPF--DSFVVQYEDT--NGQPQALLVDGDQSKILISGLEPSTPYRFLLYGL 56
           + L W    GP     +V+ Y+ T   G      V GD S + I+ LEP   Y   +Y +
Sbjct: 342 IELEWD---GPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAV 398

Query: 57  HEGKRLGPLSAEGTTGLA-PAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFL 115
                  P++A+  T L+ P G            L    +T +++ + WE    +FD + 
Sbjct: 399 ISNILSLPITAKVATHLSTPQG------------LQFKTITETTVEVQWEPFSFSFDGWE 446

Query: 116 LRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQ 175
           + F +P  +        + Q    VP    S     L+ G  Y + +  L+   ++    
Sbjct: 447 ISF-IPKNN----EGGVIAQ----VPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPP-- 495

Query: 176 GTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADG-GEPQSVQVDG 234
            T+ ++S V++ P  +   ++ +T A V W+PP ++ D   + Y L  G G   + ++  
Sbjct: 496 -TSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQP 554

Query: 235 QARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHW 294
                 +Q L PG+RYEV+V +VRG  ES+  T   TT  D P  LR  + T     L W
Sbjct: 555 PLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEW 614

Query: 295 KPPQNPVDTYD-VQVTAPGAPPLQAETP---GSAVDYPLHDLVLHTNYTATVRGLRGPNL 350
              +  V  Y  V  T  G    +   P   G      L DLV  T Y   +  +     
Sbjct: 615 DNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674

Query: 351 TSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPG 410
           + PA++   T L++PRDL     +  +  L WT+       Y ++F    G   E+ +P 
Sbjct: 675 SVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIASEVTVPK 734

Query: 411 GITSHQLLGLFPSTSYNARLQAMWG-QSLLPPVSTSFT 447
             TS+ L  L P   Y   + A  G Q  L     +FT
Sbjct: 735 DRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFT 772



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 60/265 (22%), Positives = 108/265 (40%), Gaps = 5/265 (1%)

Query: 188 PRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQ-LADGGEPQSVQVDGQARTQKLQGLIP 246
           P DL+ + I + S ++ W   P     + +SYQ  A GG     +V G      +  L P
Sbjct: 329 PEDLRVAGISDRSIELEW-DGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEP 387

Query: 247 GARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDV 306
           G  Y ++V +V     S P+T  + T    P  L+   +TE    + W+P     D +++
Sbjct: 388 GLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEI 447

Query: 307 Q-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAP 365
             +       + A+ P     +    L     Y   V  L+    + P S + +T ++ P
Sbjct: 448 SFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGP 507

Query: 366 RDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQ--NQEILLPGGITSHQLLGLFPS 423
             +  ++V+   A + W  P  +    LL +   GG+       L   ++ + +  L P 
Sbjct: 508 TQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPG 567

Query: 424 TSYNARLQAMWGQSLLPPVSTSFTT 448
           + Y   + A+ G +     +T FTT
Sbjct: 568 SRYEVSVSAVRGTNESDSATTQFTT 592


>gi|62988324 tenascin N [Homo sapiens]
          Length = 1299

 Score =  384 bits (985), Expect = e-106
 Identities = 234/674 (34%), Positives = 341/674 (50%), Gaps = 29/674 (4%)

Query: 3    LSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRL 62
            +SW   Q   D +VV+Y    G+ + + V  +QS  +++GL P   Y      +H   + 
Sbjct: 638  VSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYM-----VHVWAQK 692

Query: 63   GPLSAEGTTGLAPAGQTSEESRPRLSQLSVTD-VTTSSLRLNWEAPPGAFDSFLLRFGVP 121
            G   ++     A   QT  +S   L    VTD VT +   ++W+      D +++R+   
Sbjct: 693  GDQESKKADTKA---QTDIDSPQNL----VTDRVTENMATVSWDPVRATIDRYVVRYTSA 745

Query: 122  SPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTL 181
                          RE+ V   + S VL  LR G  Y++ ++  +G  ++      A+T 
Sbjct: 746  KDGET---------REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQT- 795

Query: 182  SPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKL 241
               ++SP++L    + E +A V+W P  +  D + V Y  A+G E + V V  +  +  L
Sbjct: 796  --DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANG-ETREVPVGKEQSSTVL 852

Query: 242  QGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPV 301
             GL PG  Y V V + +G +ES+       T  DGP  L    +TE  A + W P Q  +
Sbjct: 853  TGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPVQATI 912

Query: 302  DTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTG 361
            D Y V+ T+      +           L  L     Y   V   +G   +  A     T 
Sbjct: 913  DKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTE 972

Query: 362  LEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLF 421
            L+ PR+L    VT    +LTWT P  +  GY+L++  P G  +E+ L        L GL 
Sbjct: 973  LDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLE 1032

Query: 422  PSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNR 481
               +Y   L A  G      VST+ +T G R P P DC +  QN   AS   TI+L+G+ 
Sbjct: 1033 QGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNSNAASGLYTIYLHGDA 1092

Query: 482  ERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQ 541
             RPL V+CDMETDGGGW+VFQRR  GQ DF++ W  Y  GFG+   EFWLG + LH+LT 
Sbjct: 1093 SRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTT 1152

Query: 542  A--GDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSA 599
                 Y +RVDL+  +E+ +A YD F V S+ E Y+L +  Y GTAGD+++YH+G  F+ 
Sbjct: 1153 GTPARYEVRVDLQTANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDALTYHNGWKFTT 1212

Query: 600  RDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEM 659
             DRD +  L +CA+++ G WWY+NCH AN NG YG T   +GV+W  WKG EFS+P+ E+
Sbjct: 1213 FDRDNDIALSNCALTHHGGWWYKNCHLANPNGRYGETKHSEGVNWEPWKGHEFSIPYVEL 1272

Query: 660  KLRPRNF-RSPAGG 672
            K+RP  + R P  G
Sbjct: 1273 KIRPHGYSREPVLG 1286



 Score =  115 bits (289), Expect = 1e-25
 Identities = 107/406 (26%), Positives = 165/406 (40%), Gaps = 22/406 (5%)

Query: 31  VDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQL 90
           V  +Q    I GL P T Y   L  +       P     TT LA  G             
Sbjct: 309 VPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAW---------- 358

Query: 91  SVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLR 150
            VTD T +SL + WE P    D + LR+G  +   +     P    +   P +R+   + 
Sbjct: 359 -VTDETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVP----KSSDPKSRYD--IT 411

Query: 151 DLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPS 210
            L  GT Y +T+  +RG  +   I    RT    ++SP ++    + E +A V+W P  +
Sbjct: 412 GLHPGTEYKITVVPMRGELEGKPILLNGRT---EIDSPTNVVTDRVTEDTATVSWDPVQA 468

Query: 211 RADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFL 270
             D + V Y  AD G+ + + V     +  L GL PG  Y+V V + RG + S+      
Sbjct: 469 VIDKYVVRYTSAD-GDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNA 527

Query: 271 TTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYP-L 329
            T  D P  L    +TE  A + W P Q  +D Y V+ T+      +    G       L
Sbjct: 528 LTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVL 587

Query: 330 HDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRP 389
             L     YT  V   +G   +  A     T +++P++L    VT   A ++W       
Sbjct: 588 TGLRPGVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAI 647

Query: 390 AGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWG 435
             Y++ + + GG+ +E+ +    +S  L GL P   Y   + A  G
Sbjct: 648 DKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKG 693



 Score =  112 bits (281), Expect = 9e-25
 Identities = 102/439 (23%), Positives = 169/439 (38%), Gaps = 31/439 (7%)

Query: 3   LSWSVAQGPFDSFVVQYEDTNGQPQALLV----DGDQSKILISGLEPSTPYRFLLYGLHE 58
           + W       D + ++Y    GQ  A +        +S+  I+GL P T Y+  +  +  
Sbjct: 369 VEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRG 428

Query: 59  GKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTD-VTTSSLRLNWEAPPGAFDSFLLR 117
                P+   G T +                  VTD VT  +  ++W+      D +++R
Sbjct: 429 ELEGKPILLNGRTEIDSPTNV------------VTDRVTEDTATVSWDPVQAVIDKYVVR 476

Query: 118 FGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGT 177
           +      T          +E+ V     S VL  L+ G  Y + ++  RG   +      
Sbjct: 477 YTSADGDT----------KEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTN 526

Query: 178 ARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQAR 237
           A T    ++SP +L    + E +A ++W P  +  D + V Y  AD  E + V V  +  
Sbjct: 527 ALT---EIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQS 583

Query: 238 TQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPP 297
           +  L GL PG  Y V V + +G  ES+       T  D P  L    +TE  A + W P 
Sbjct: 584 STVLTGLRPGVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPV 643

Query: 298 QNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASIT 357
           Q  +D Y V+ T+ G    +           L  L     Y   V   +G   +  A   
Sbjct: 644 QAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTK 703

Query: 358 FTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSF-HTPGGQNQEILLPGGITSHQ 416
             T +++P++L    VT   A ++W         Y++ +     G+ +E+ +    +S  
Sbjct: 704 AQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTV 763

Query: 417 LLGLFPSTSYNARLQAMWG 435
           L GL P   Y   + A  G
Sbjct: 764 LTGLRPGVEYTVHVWAQKG 782



 Score =  100 bits (249), Expect = 4e-21
 Identities = 99/373 (26%), Positives = 153/373 (41%), Gaps = 24/373 (6%)

Query: 68  EGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLE 127
           EG TGL  A   + +       L +   T  SL ++WE P    D +LL +         
Sbjct: 252 EGFTGLDCAQVVTPQG------LQLLKNTEDSLLVSWE-PSSQVDHYLLSY--------Y 296

Query: 128 PHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLES 187
           P  + L  +++ VP  +HS  +  L  GT Y +TL  ++    +      A T   VL +
Sbjct: 297 PLGKELSGKQIQVPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGT 356

Query: 188 PRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQV----DGQARTQKLQG 243
                 ++  E S  V W  P +  D +K+ Y    G E   V V    D ++R   + G
Sbjct: 357 ---AWVTDETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSR-YDITG 412

Query: 244 LIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDT 303
           L PG  Y++TVV +RG  E +P+     T  D PT +    +TE  A + W P Q  +D 
Sbjct: 413 LHPGTEYKITVVPMRGELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDK 472

Query: 304 YDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLE 363
           Y V+ T+      +           L  L     Y   V   RG   +  A     T ++
Sbjct: 473 YVVRYTSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEID 532

Query: 364 APRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQ-NQEILLPGGITSHQLLGLFP 422
           +P +L    VT  TA ++W         Y++ + +   Q  +E+L+    +S  L GL P
Sbjct: 533 SPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRP 592

Query: 423 STSYNARLQAMWG 435
              Y   + A  G
Sbjct: 593 GVEYTVHVWAQKG 605


>gi|8051586 ficolin 2 isoform b precursor [Homo sapiens]
          Length = 275

 Score =  197 bits (501), Expect = 3e-50
 Identities = 102/215 (47%), Positives = 135/215 (62%), Gaps = 11/215 (5%)

Query: 456 PRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDW 515
           PR C + +  G   S   TI+L   R  PL V CDM+TDGGGW VFQRR+DG  DF+RDW
Sbjct: 64  PRTCKDLLDRGHFLSGWHTIYLPDCR--PLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDW 121

Query: 516 EDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDL-RAGDEAVFAQYDSFHVDSAAEYY 574
             Y  GFG+  GEFWLGN+ +H+LT  G   +RVDL    D   FA+Y SF V   AE Y
Sbjct: 122 ATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKY 181

Query: 575 RLHLEGY-HGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLY 633
            L L  +  G+AGDS+++H+   FS +D+D +    +CAV ++GAWWY+NCH +NLNG Y
Sbjct: 182 NLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRY 241

Query: 634 -----GSTVDHQGVSWYHWKGFEFSVPFTEMKLRP 663
                GS  +  G++W   KG+ +S   +EMK+RP
Sbjct: 242 LRGTHGSFAN--GINWKSGKGYNYSYKVSEMKVRP 274


>gi|61744445 ficolin 2 isoform a precursor [Homo sapiens]
          Length = 313

 Score =  197 bits (501), Expect = 3e-50
 Identities = 102/215 (47%), Positives = 135/215 (62%), Gaps = 11/215 (5%)

Query: 456 PRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDW 515
           PR C + +  G   S   TI+L   R  PL V CDM+TDGGGW VFQRR+DG  DF+RDW
Sbjct: 102 PRTCKDLLDRGHFLSGWHTIYLPDCR--PLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDW 159

Query: 516 EDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDL-RAGDEAVFAQYDSFHVDSAAEYY 574
             Y  GFG+  GEFWLGN+ +H+LT  G   +RVDL    D   FA+Y SF V   AE Y
Sbjct: 160 ATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKY 219

Query: 575 RLHLEGY-HGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLY 633
            L L  +  G+AGDS+++H+   FS +D+D +    +CAV ++GAWWY+NCH +NLNG Y
Sbjct: 220 NLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRY 279

Query: 634 -----GSTVDHQGVSWYHWKGFEFSVPFTEMKLRP 663
                GS  +  G++W   KG+ +S   +EMK+RP
Sbjct: 280 LRGTHGSFAN--GINWKSGKGYNYSYKVSEMKVRP 312


>gi|8051584 ficolin 1 precursor [Homo sapiens]
          Length = 326

 Score =  191 bits (484), Expect = 2e-48
 Identities = 99/213 (46%), Positives = 136/213 (63%), Gaps = 7/213 (3%)

Query: 456 PRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDW 515
           PR+C + +  G   S   TI+L   R  PL V CDM+TDGGGW VFQRRMDG  DF+RDW
Sbjct: 115 PRNCKDLLDRGYFLSGWHTIYLPDCR--PLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDW 172

Query: 516 EDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGD-EAVFAQYDSFHVDSAAEYY 574
             Y  GFG+  GEFWLGN+ +H+LT  G   +RVDL   +    FA+Y SF V   AE Y
Sbjct: 173 AAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKY 232

Query: 575 RLHLEGY-HGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLY 633
           +L L  +  G+AG+S++ H+ + FS +D+D +    +CA  ++GAWWY +CH +NLNGLY
Sbjct: 233 KLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLY 292

Query: 634 --GSTVDH-QGVSWYHWKGFEFSVPFTEMKLRP 663
             G    +  G++W   KG+++S   +EMK+RP
Sbjct: 293 LMGPHESYANGINWSAAKGYKYSYKVSEMKVRP 325


>gi|223029463 fibrinogen C domain containing 1 [Homo sapiens]
          Length = 461

 Score =  188 bits (477), Expect = 2e-47
 Identities = 95/217 (43%), Positives = 130/217 (59%), Gaps = 10/217 (4%)

Query: 456 PRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDW 515
           PRDC + + +G       ++F   +      V+CDM TDGGGW VFQRR DG  +F+R W
Sbjct: 241 PRDCLDVLLSGQQDDGVYSVFPT-HYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGW 299

Query: 516 EDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDE-AVFAQYDS-----FHVDS 569
           + Y  GFG ++GE WLG + +H+LT    Y + VDL   +    +A+Y S     F VD 
Sbjct: 300 DAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDP 359

Query: 570 AAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANL 629
             + Y L +  Y GTAGDS+  HSG  F+ +DRD +    +CA  YRGAWWYRNCH +NL
Sbjct: 360 EEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNL 419

Query: 630 NGLY--GSTVDH-QGVSWYHWKGFEFSVPFTEMKLRP 663
           NG Y  G+   +  GV W  W G+++S+ F+EMK+RP
Sbjct: 420 NGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRP 456


>gi|223029461 fibrinogen C domain containing 1 [Homo sapiens]
          Length = 461

 Score =  188 bits (477), Expect = 2e-47
 Identities = 95/217 (43%), Positives = 130/217 (59%), Gaps = 10/217 (4%)

Query: 456 PRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDW 515
           PRDC + + +G       ++F   +      V+CDM TDGGGW VFQRR DG  +F+R W
Sbjct: 241 PRDCLDVLLSGQQDDGVYSVFPT-HYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGW 299

Query: 516 EDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDE-AVFAQYDS-----FHVDS 569
           + Y  GFG ++GE WLG + +H+LT    Y + VDL   +    +A+Y S     F VD 
Sbjct: 300 DAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDP 359

Query: 570 AAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANL 629
             + Y L +  Y GTAGDS+  HSG  F+ +DRD +    +CA  YRGAWWYRNCH +NL
Sbjct: 360 EEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNL 419

Query: 630 NGLY--GSTVDH-QGVSWYHWKGFEFSVPFTEMKLRP 663
           NG Y  G+   +  GV W  W G+++S+ F+EMK+RP
Sbjct: 420 NGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRP 456


>gi|20532340 angiopoietin 1 [Homo sapiens]
          Length = 498

 Score =  177 bits (448), Expect = 4e-44
 Identities = 90/220 (40%), Positives = 134/220 (60%), Gaps = 10/220 (4%)

Query: 454 PFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWR 513
           PF RDC +  Q G   S   TI++N N   P  VFC+M+ +GGGW V Q R DG  DF R
Sbjct: 282 PF-RDCADVYQAGFNKSGIYTIYIN-NMPEPKKVFCNMDVNGGGWTVIQHREDGSLDFQR 339

Query: 514 DWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGD-EAVFAQYDSFHVDSAAE 572
            W++Y  GFGN SGE+WLGNE + ++T    Y +R++L   +    ++QYD FH+ +  +
Sbjct: 340 GWKEYKMGFGNPSGEYWLGNEFIFAITSQRQYMLRIELMDWEGNRAYSQYDRFHIGNEKQ 399

Query: 573 YYRLHLEGYHGTAG--DSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLN 630
            YRL+L+G+ GTAG   S+  H G+ FS +D D ++ +  CA+   G WW+  C  +NLN
Sbjct: 400 NYRLYLKGHTGTAGKQSSLILH-GADFSTKDADNDNCMCKCALMLTGGWWFDACGPSNLN 458

Query: 631 GL-YGSTVDH---QGVSWYHWKGFEFSVPFTEMKLRPRNF 666
           G+ Y +  +H    G+ W+++KG  +S+  T M +RP +F
Sbjct: 459 GMFYTAGQNHGKLNGIKWHYFKGPSYSLRSTTMMIRPLDF 498


>gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens]
          Length = 288

 Score =  176 bits (445), Expect = 8e-44
 Identities = 94/214 (43%), Positives = 120/214 (56%), Gaps = 7/214 (3%)

Query: 454 PFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWR 513
           P PR+C E +  GA  S    + L   R  P  VFCDM+T+GGGWLVFQRR DG  DF+R
Sbjct: 77  PGPRNCRELLSQGATLSGWYHLCLPEGRALP--VFCDMDTEGGGWLVFQRRQDGSVDFFR 134

Query: 514 DWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLR-AGDEAVFAQYDSFHVDSAAE 572
            W  Y  GFGN   EFWLGNE LH LT  G++ +RV+L        FA Y +F +    +
Sbjct: 135 SWSSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVD 194

Query: 573 YYRLHLEGY-HGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNG 631
           +Y+L L  +  GTAGDS+S HSG  F+  D D +S   +CAV   GAWWY +C+ +NLNG
Sbjct: 195 HYQLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNG 254

Query: 632 LYG---STVDHQGVSWYHWKGFEFSVPFTEMKLR 662
            Y    +     G+ W   +G         M LR
Sbjct: 255 RYAVSEAAAHKYGIDWASGRGVGHPYRRVRMMLR 288


>gi|23111005 microfibrillar-associated protein 4 [Homo sapiens]
          Length = 255

 Score =  174 bits (442), Expect = 2e-43
 Identities = 92/217 (42%), Positives = 127/217 (58%), Gaps = 11/217 (5%)

Query: 456 PRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDW 515
           P DC +    G  +     I+ +G    P+ VFCDM T+GG W VFQ+R +G   F+R W
Sbjct: 38  PLDCDDIYAQGYQSDGVYLIYPSGPSV-PVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGW 96

Query: 516 EDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLR-AGDEAVFAQYDSFHVDSAA--- 571
            DY  GFG   GE+WLG + +H LT    Y +RVDL    +   +A+Y  F +   A   
Sbjct: 97  NDYKLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSA 156

Query: 572 --EYYRLHLEGYH-GTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYAN 628
             + Y L + G+  G AGDS+SYHSG  FS  DRD +  + +CA    GA+W+R+CH+AN
Sbjct: 157 EEDGYTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFAN 216

Query: 629 LNGLY--GSTVDH-QGVSWYHWKGFEFSVPFTEMKLR 662
           LNG Y  GS + +  G++W  WKGF +S+  TEMK+R
Sbjct: 217 LNGFYLGGSHLSYANGINWAQWKGFYYSLKRTEMKIR 253


>gi|27754776 ficolin 3 isoform 1 precursor [Homo sapiens]
          Length = 299

 Score =  174 bits (441), Expect = 2e-43
 Identities = 93/212 (43%), Positives = 119/212 (56%), Gaps = 7/212 (3%)

Query: 456 PRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDW 515
           PR+C E +  GA  S    + L   R  P  VFCDM+T+GGGWLVFQRR DG  DF+R W
Sbjct: 90  PRNCRELLSQGATLSGWYHLCLPEGRALP--VFCDMDTEGGGWLVFQRRQDGSVDFFRSW 147

Query: 516 EDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLR-AGDEAVFAQYDSFHVDSAAEYY 574
             Y  GFGN   EFWLGNE LH LT  G++ +RV+L        FA Y +F +    ++Y
Sbjct: 148 SSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHY 207

Query: 575 RLHLEGY-HGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLY 633
           +L L  +  GTAGDS+S HSG  F+  D D +S   +CAV   GAWWY +C+ +NLNG Y
Sbjct: 208 QLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNGRY 267

Query: 634 G---STVDHQGVSWYHWKGFEFSVPFTEMKLR 662
               +     G+ W   +G         M LR
Sbjct: 268 AVSEAAAHKYGIDWASGRGVGHPYRRVRMMLR 299


>gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]
          Length = 493

 Score =  172 bits (437), Expect = 7e-43
 Identities = 87/215 (40%), Positives = 128/215 (59%), Gaps = 11/215 (5%)

Query: 457 RDCGEEMQNGAGASRTSTIFL--NGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRD 514
           RDC + +++G     TS+I+L    N  R + V+CD   D GGW V QRR+DG  +F+R+
Sbjct: 276 RDCLQALEDGHD---TSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRN 332

Query: 515 WEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRA-GDEAVFAQYDSFHVDSAAEY 573
           WE Y  GFGNI GE+WLG E ++ LT  G+Y + V +       VFA+Y SF ++  +EY
Sbjct: 333 WETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEY 392

Query: 574 YRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLY 633
           Y+L L  YHG AGDS ++H+G  F+  DRD +    +CA   +G WWY  C ++NLNG++
Sbjct: 393 YKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVW 452

Query: 634 GSTVDHQ-----GVSWYHWKGFEFSVPFTEMKLRP 663
                ++     GV W  ++G  +S+    M +RP
Sbjct: 453 YRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487


>gi|7705276 angiopoietin 4 [Homo sapiens]
          Length = 503

 Score =  171 bits (432), Expect = 3e-42
 Identities = 88/214 (41%), Positives = 130/214 (60%), Gaps = 9/214 (4%)

Query: 457 RDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWE 516
           +DC E  ++GA AS   TI ++ N  +P  VFCD+++ GG W + QRR +G  +F R+W+
Sbjct: 289 QDCAEIQRSGASASGVYTIQVS-NATKPRKVFCDLQSSGGRWTLIQRRENGTVNFQRNWK 347

Query: 517 DYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLR--AGDEAVFAQYDSFHVDSAAEYY 574
           DY  GFG+ +GE WLGNE +H LT+   YS+RV+L+   G EA +AQY+ FH+ S  + Y
Sbjct: 348 DYKQGFGDPAGEHWLGNEVVHQLTRRAAYSLRVELQDWEGHEA-YAQYEHFHLGSENQLY 406

Query: 575 RLHLEGYHGTAG-DSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLY 633
           RL + GY G+AG  S      + FS  D D +  L  CA    G WW+  C  +NLNG+Y
Sbjct: 407 RLSVVGYSGSAGRQSSLVLQNTSFSTLDSDNDHCLCKCAQVMSGGWWFDACGLSNLNGVY 466

Query: 634 GSTVDHQ----GVSWYHWKGFEFSVPFTEMKLRP 663
               D++    G+ W+++KG  +S+  + M +RP
Sbjct: 467 YHAPDNKYKMDGIRWHYFKGPSYSLRASRMMIRP 500


>gi|169646754 angiopoietin 2 isoform c precursor [Homo sapiens]
          Length = 444

 Score =  168 bits (425), Expect = 2e-41
 Identities = 85/217 (39%), Positives = 124/217 (57%), Gaps = 9/217 (4%)

Query: 457 RDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWE 516
           RDC E  ++G   +   T+    + E  +  +CDME  GGGW + QRR DG  DF R W+
Sbjct: 230 RDCAEVFKSGHTTNGIYTLTFPNSTEE-IKAYCDMEAGGGGWTIIQRREDGSVDFQRTWK 288

Query: 517 DYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLR--AGDEAVFAQYDSFHVDSAAEYY 574
           +Y  GFGN SGE+WLGNE +  LT    Y +++ L+   G+EA ++ Y+ F++ S    Y
Sbjct: 289 EYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEA-YSLYEHFYLSSEELNY 347

Query: 575 RLHLEGYHGTAGDSMSY-HSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLY 633
           R+HL+G  GTAG   S    G+ FS +D D +  +  C+    G WW+  C  +NLNG+Y
Sbjct: 348 RIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMY 407

Query: 634 ----GSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNF 666
                +T    G+ WY+WKG  +S+  T M +RP +F
Sbjct: 408 YPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF 444


>gi|169646749 angiopoietin 2 isoform b precursor [Homo sapiens]
          Length = 495

 Score =  168 bits (425), Expect = 2e-41
 Identities = 85/217 (39%), Positives = 124/217 (57%), Gaps = 9/217 (4%)

Query: 457 RDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWE 516
           RDC E  ++G   +   T+    + E  +  +CDME  GGGW + QRR DG  DF R W+
Sbjct: 281 RDCAEVFKSGHTTNGIYTLTFPNSTEE-IKAYCDMEAGGGGWTIIQRREDGSVDFQRTWK 339

Query: 517 DYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLR--AGDEAVFAQYDSFHVDSAAEYY 574
           +Y  GFGN SGE+WLGNE +  LT    Y +++ L+   G+EA ++ Y+ F++ S    Y
Sbjct: 340 EYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEA-YSLYEHFYLSSEELNY 398

Query: 575 RLHLEGYHGTAGDSMSY-HSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLY 633
           R+HL+G  GTAG   S    G+ FS +D D +  +  C+    G WW+  C  +NLNG+Y
Sbjct: 399 RIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMY 458

Query: 634 ----GSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNF 666
                +T    G+ WY+WKG  +S+  T M +RP +F
Sbjct: 459 YPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF 495


>gi|4557315 angiopoietin 2 isoform a precursor [Homo sapiens]
          Length = 496

 Score =  168 bits (425), Expect = 2e-41
 Identities = 85/217 (39%), Positives = 124/217 (57%), Gaps = 9/217 (4%)

Query: 457 RDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWE 516
           RDC E  ++G   +   T+    + E  +  +CDME  GGGW + QRR DG  DF R W+
Sbjct: 282 RDCAEVFKSGHTTNGIYTLTFPNSTEE-IKAYCDMEAGGGGWTIIQRREDGSVDFQRTWK 340

Query: 517 DYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLR--AGDEAVFAQYDSFHVDSAAEYY 574
           +Y  GFGN SGE+WLGNE +  LT    Y +++ L+   G+EA ++ Y+ F++ S    Y
Sbjct: 341 EYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEA-YSLYEHFYLSSEELNY 399

Query: 575 RLHLEGYHGTAGDSMSY-HSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLY 633
           R+HL+G  GTAG   S    G+ FS +D D +  +  C+    G WW+  C  +NLNG+Y
Sbjct: 400 RIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMY 459

Query: 634 ----GSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNF 666
                +T    G+ WY+WKG  +S+  T M +RP +F
Sbjct: 460 YPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF 496


>gi|4757752 angiopoietin-like 1 precursor [Homo sapiens]
          Length = 491

 Score =  167 bits (423), Expect = 3e-41
 Identities = 85/244 (34%), Positives = 137/244 (56%), Gaps = 17/244 (6%)

Query: 436 QSLLPP--VSTSFTTGGLRIPFP--------RDCGEEMQNGAGASRTSTIFLNGNRERPL 485
           + L+PP  ++TS T    +IP          +DC +  + G   S    I    N   P+
Sbjct: 247 RDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPE-NSNGPM 305

Query: 486 NVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDY 545
            ++C+   D GGW V Q+R DG  +F+R+WE+Y  GFGNI GE+WLG E ++ L+   +Y
Sbjct: 306 QLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNY 365

Query: 546 SMRVDLRA-GDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDP 604
            + ++L    D+ V+A+Y SF ++  +E+YRL L  Y G AGDSM +H+G  F+  DRD 
Sbjct: 366 KLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDK 425

Query: 605 NSLLISCAVSYRGAWWYRNCHYANLNGL-----YGSTVDHQGVSWYHWKGFEFSVPFTEM 659
           +    +CA  ++G WWY  C ++NLNG+     +  +    G+ W  ++G  +S+   +M
Sbjct: 426 DMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQM 485

Query: 660 KLRP 663
            ++P
Sbjct: 486 MIKP 489


>gi|10863949 angiopoietin-like 7 [Homo sapiens]
          Length = 346

 Score =  164 bits (416), Expect = 2e-40
 Identities = 78/189 (41%), Positives = 115/189 (60%), Gaps = 7/189 (3%)

Query: 485 LNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGD 544
           L VFCDMET GGGW + QRR  G   F+RDW+ Y  GFG+I G+FWLGNE +H L++   
Sbjct: 158 LEVFCDMETSGGGWTIIQRRKSGLVSFYRDWKQYKQGFGSIRGDFWLGNEHIHRLSRQ-P 216

Query: 545 YSMRVDLRAGDEAV-FAQYDSFHVDSAAEYYRLHLEGYHGTAG-DSMSYHSGSVFSARDR 602
             +RV++   +  + +A+Y  F + +    YRL L  Y G  G D++ YH+ + FS +D+
Sbjct: 217 TRLRVEMEDWEGNLRYAEYSHFVLGNELNSYRLFLGNYTGNVGNDALQYHNNTAFSTKDK 276

Query: 603 DPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDH----QGVSWYHWKGFEFSVPFTE 658
           D ++ L  CA   +G +WY  C  +NLNG+Y    +H     G++WY W G  +S+   E
Sbjct: 277 DNDNCLDKCAQLRKGGYWYNCCTDSNLNGVYYRLGEHNKHLDGITWYGWHGSTYSLKRVE 336

Query: 659 MKLRPRNFR 667
           MK+RP +F+
Sbjct: 337 MKIRPEDFK 345


>gi|29893555 angiopoietin-like 6 [Homo sapiens]
          Length = 470

 Score =  161 bits (408), Expect = 2e-39
 Identities = 98/282 (34%), Positives = 147/282 (52%), Gaps = 22/282 (7%)

Query: 400 GGQNQEILLPGGITSHQLLGLFPSTSYNARL-------QAMWGQSLLPPVSTSFTTGGLR 452
           GGQ Q++L P  +     + L  STS  +R+       Q    Q    P+++    G   
Sbjct: 190 GGQ-QQVLPPPPLVPVVPVRLVGSTSDTSRMLDPAPEPQRDQTQRQQEPMASPMPAGHPA 248

Query: 453 IPFP-----RDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDG 507
           +P       +DC E  Q  AG  ++    L   R   ++V+C+ + +GGGW V QRR DG
Sbjct: 249 VPTKPVGPWQDCAEARQ--AGHEQSGVYELRVGRH-VVSVWCEQQLEGGGWTVIQRRQDG 305

Query: 508 QTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRA-GDEAVFAQYDSFH 566
             +F+  W+ Y  GFG   GE+WLG E ++ LT  GD+ + V L   G     A YD F 
Sbjct: 306 SVNFFTTWQHYKAGFGRPDGEYWLGLEPVYQLTSRGDHELLVLLEDWGGRGARAHYDGFS 365

Query: 567 VDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHY 626
           ++  +++YRL L  YHG AGDS+S+H+   FS  DRD +S   +CA+  RG WWY  C +
Sbjct: 366 LEPESDHYRLRLGQYHGDAGDSLSWHNDKPFSTVDRDRDSYSGNCALYQRGGWWYHACAH 425

Query: 627 ANLNGLYGSTVDHQ-----GVSWYHWKGFEFSVPFTEMKLRP 663
           +NLNG++     ++     GV W  ++G  +S+    M +RP
Sbjct: 426 SNLNGVWHHGGHYRSRYQDGVYWAEFRGGAYSLRKAAMLIRP 467


>gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E
           preproprotein [Homo sapiens]
          Length = 866

 Score =  160 bits (404), Expect = 5e-39
 Identities = 96/237 (40%), Positives = 133/237 (56%), Gaps = 34/237 (14%)

Query: 457 RDCGEEMQNGAGASRTS--TIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRD 514
           RDC + +Q     +++    I L G+  +  +V+CD ET  GGWL+ Q+RMDG  +F R 
Sbjct: 630 RDCDDVLQTHPSGTQSGIFNIKLPGS-SKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRT 688

Query: 515 WEDYAHGFGNIS----GEFWLGNEALHSLTQAGDYSMRVDLR--AGDEAVFAQYDSFHVD 568
           W+DY  GFG+++    GEFWLGN+ LH LTQ G   +RV+L   AG+EA +A+Y  F V 
Sbjct: 689 WQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSV-LRVELEDWAGNEA-YAEY-HFRVG 745

Query: 569 SAAEYYRLHLEGYHGTAGDSM-----------SYHSGSVFSARDRDPNSLLISCAVSYRG 617
           S AE Y L +  Y GTAGD++           + H+   FS  DRD +    +CA  Y G
Sbjct: 746 SEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGG 805

Query: 618 AWWYRNCHYANLNGLY--GSTVD---------HQGVSWYHWKGFEFSVPFTEMKLRP 663
            WWY NC  ANLNG+Y  G + D           GV W  ++G ++S+    MK+RP
Sbjct: 806 GWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRP 862


>gi|42544202 fibrinogen-like 1 precursor [Homo sapiens]
          Length = 312

 Score =  158 bits (400), Expect = 1e-38
 Identities = 82/200 (41%), Positives = 116/200 (58%), Gaps = 20/200 (10%)

Query: 486 NVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNI---SGEFWLGNEALHSLTQA 542
           +V+CDM +DGGGW V QRR DG  +F R W+DY +GFGN     GE+WLGN+ LH LT  
Sbjct: 109 SVYCDM-SDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQKHGEYWLGNKNLHFLTTQ 167

Query: 543 GDYSMRVDLRAGDE-AVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSM-----------S 590
            DY++++DL   ++ + +AQY +F V     +Y L++  Y GTAGDS+           +
Sbjct: 168 EDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSLAGNFHPEVQWWA 227

Query: 591 YHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGS----TVDHQGVSWYH 646
            H    FS  DRD ++   +CA   +  WW+  CH ANLNG+Y S         G+ WY 
Sbjct: 228 SHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKTDNGIVWYT 287

Query: 647 WKGFEFSVPFTEMKLRPRNF 666
           W G+ +S+    MK+RP +F
Sbjct: 288 WHGWWYSLKSVVMKIRPNDF 307


>gi|42544200 fibrinogen-like 1 precursor [Homo sapiens]
          Length = 312

 Score =  158 bits (400), Expect = 1e-38
 Identities = 82/200 (41%), Positives = 116/200 (58%), Gaps = 20/200 (10%)

Query: 486 NVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNI---SGEFWLGNEALHSLTQA 542
           +V+CDM +DGGGW V QRR DG  +F R W+DY +GFGN     GE+WLGN+ LH LT  
Sbjct: 109 SVYCDM-SDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQKHGEYWLGNKNLHFLTTQ 167

Query: 543 GDYSMRVDLRAGDE-AVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSM-----------S 590
            DY++++DL   ++ + +AQY +F V     +Y L++  Y GTAGDS+           +
Sbjct: 168 EDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSLAGNFHPEVQWWA 227

Query: 591 YHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGS----TVDHQGVSWYH 646
            H    FS  DRD ++   +CA   +  WW+  CH ANLNG+Y S         G+ WY 
Sbjct: 228 SHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKTDNGIVWYT 287

Query: 647 WKGFEFSVPFTEMKLRPRNF 666
           W G+ +S+    MK+RP +F
Sbjct: 288 WHGWWYSLKSVVMKIRPNDF 307


>gi|42544198 fibrinogen-like 1 precursor [Homo sapiens]
          Length = 312

 Score =  158 bits (400), Expect = 1e-38
 Identities = 82/200 (41%), Positives = 116/200 (58%), Gaps = 20/200 (10%)

Query: 486 NVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNI---SGEFWLGNEALHSLTQA 542
           +V+CDM +DGGGW V QRR DG  +F R W+DY +GFGN     GE+WLGN+ LH LT  
Sbjct: 109 SVYCDM-SDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQKHGEYWLGNKNLHFLTTQ 167

Query: 543 GDYSMRVDLRAGDE-AVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSM-----------S 590
            DY++++DL   ++ + +AQY +F V     +Y L++  Y GTAGDS+           +
Sbjct: 168 EDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSLAGNFHPEVQWWA 227

Query: 591 YHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGS----TVDHQGVSWYH 646
            H    FS  DRD ++   +CA   +  WW+  CH ANLNG+Y S         G+ WY 
Sbjct: 228 SHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKTDNGIVWYT 287

Query: 647 WKGFEFSVPFTEMKLRPRNF 666
           W G+ +S+    MK+RP +F
Sbjct: 288 WHGWWYSLKSVVMKIRPNDF 307


>gi|42544189 fibrinogen-like 1 precursor [Homo sapiens]
          Length = 312

 Score =  158 bits (400), Expect = 1e-38
 Identities = 82/200 (41%), Positives = 116/200 (58%), Gaps = 20/200 (10%)

Query: 486 NVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNI---SGEFWLGNEALHSLTQA 542
           +V+CDM +DGGGW V QRR DG  +F R W+DY +GFGN     GE+WLGN+ LH LT  
Sbjct: 109 SVYCDM-SDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQKHGEYWLGNKNLHFLTTQ 167

Query: 543 GDYSMRVDLRAGDE-AVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSM-----------S 590
            DY++++DL   ++ + +AQY +F V     +Y L++  Y GTAGDS+           +
Sbjct: 168 EDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSLAGNFHPEVQWWA 227

Query: 591 YHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGS----TVDHQGVSWYH 646
            H    FS  DRD ++   +CA   +  WW+  CH ANLNG+Y S         G+ WY 
Sbjct: 228 SHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKTDNGIVWYT 287

Query: 647 WKGFEFSVPFTEMKLRPRNF 666
           W G+ +S+    MK+RP +F
Sbjct: 288 WHGWWYSLKSVVMKIRPNDF 307


>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
          Length = 2330

 Score =  148 bits (373), Expect = 2e-35
 Identities = 118/479 (24%), Positives = 203/479 (42%), Gaps = 31/479 (6%)

Query: 3    LSWSVAQGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGK 60
            + W  +  P   + V     NG  P      G DQ+++ I GL+P+  Y   +Y  +   
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619

Query: 61   RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
               PL     T +          RP+   L+ TDV   S+++ WE+P G    + + +  
Sbjct: 1620 ESQPLVQTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSS 1668

Query: 121  PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
            P     E  P P         G   +A L+ LR G+ Y++++  L    ++  + GT  T
Sbjct: 1669 PEDGIHELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1720

Query: 181  LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQ 239
              P   +P DL+F+++  TS    W PP  +   ++V     +   P + + +   + + 
Sbjct: 1721 AIP---APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1777

Query: 240  KLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPP 297
             + GL+   +YEV+V +++    S P  G +TT+ +   P + R  + TE    + W+  
Sbjct: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1837

Query: 298  QNPVDTYDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASI 356
               +  + V  V A G  P+Q         Y +  L   T+Y   +  L     +SP  I
Sbjct: 1838 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897

Query: 357  TFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITS 414
              +T ++AP +L     TP + L++W  P  R  GY++ +  PG   +E++     G+T 
Sbjct: 1898 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 1957

Query: 415  HQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTS 473
              + GL P T Y   + A+       P+     T   + PF    G +  NG     TS
Sbjct: 1958 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-VQKTPFVTHPGYDTGNGIQLPGTS 2015



 Score =  119 bits (299), Expect = 7e-27
 Identities = 108/440 (24%), Positives = 181/440 (41%), Gaps = 36/440 (8%)

Query: 1    MRLSWSVAQGP-FDSFVVQYEDTNGQPQALL---VDGDQSKILISGLEPSTPYRFLLYGL 56
            + +SW  +  P    + +    TNGQ    L   V  DQS      L P   Y   +Y +
Sbjct: 1191 LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250

Query: 57   HEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGA-FDSFL 115
             + K   P+S            T   + P  + L  T++   ++R+ W  PP     +FL
Sbjct: 1251 KDDKESVPIS-----------DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299

Query: 116  LRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQ 175
            +R+   SP   E         EL +  + ++ VL +L  GT Y +++  +   H++  ++
Sbjct: 1300 VRY---SPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1351

Query: 176  GTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLAD-GGEPQSVQVDG 234
            G  +T    L+SP  + FS+I   S  V+W+ P +    +++ +      G P+  +V  
Sbjct: 1352 GRQKT---GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408

Query: 235  QARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHW 294
               +  L  L PG  Y V++V++ G EES  L G  +TV D P  L  +  T    ++ W
Sbjct: 1409 SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISW 1468

Query: 295  KPPQNPVDTYDVQV--TAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRG----P 348
              P   V  Y +    T   +P  +   PGS     +  L    +YT TV  + G    P
Sbjct: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528

Query: 349  NLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILL 408
              + P SI + T ++ P  ++  +V   +  + W        GY ++     G       
Sbjct: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588

Query: 409  PGG--ITSHQLLGLFPSTSY 426
              G   T   + GL P+  Y
Sbjct: 1589 TAGPDQTEMTIEGLQPTVEY 1608



 Score =  117 bits (294), Expect = 3e-26
 Identities = 115/480 (23%), Positives = 197/480 (41%), Gaps = 57/480 (11%)

Query: 3    LSWSVAQ-GPFDSFVVQYEDTN--GQPQALLVDGDQSKILISGLEPSTPYRFLL-----Y 54
            + W+  Q      +++++   N  G+ +   + G  +   I GL+P   Y   L     Y
Sbjct: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687

Query: 55   GLHEGKRLGPLSAEGTTGLAP---AGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAF 111
            G  E  R    +   +T +      G+T+  S    +  SVT++T SS  ++W +     
Sbjct: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747

Query: 112  DSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171
              F + + +      EP       + L +P T  S  + DL  G  Y + +Y +    + 
Sbjct: 748  SGFRVEYELSEEGD-EP-------QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQ 799

Query: 172  DSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQ 231
              I  T++T +P  ++P D    ++ +TS  V W  P +    +++ Y  +  G    + 
Sbjct: 800  SLILSTSQTTAP--DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857

Query: 232  VDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPL--------TGFLTTVPDGPTQLRAL 283
            +   A +  L  L PG +Y +T+ +V   +ES P+        T    TVP  P  L+ +
Sbjct: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP-SPRDLQFV 916

Query: 284  NLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVR 343
             +T+    + W PP++ V  Y V V     P    +            L +  N  A V 
Sbjct: 917  EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQR-----------LPISRNTFAEVT 965

Query: 344  GLRGPNLT--------------SPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRP 389
            GL  P +T               P +   TT L+AP +L+    T  T L+ WT P  + 
Sbjct: 966  GL-SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024

Query: 390  AGYLLSFH-TPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 448
             GY L+   T  GQ ++  +   ++ + L  L P++ Y   L A+ G    P  +  FTT
Sbjct: 1025 TGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084



 Score =  106 bits (264), Expect = 8e-23
 Identities = 83/358 (23%), Positives = 143/358 (39%), Gaps = 26/358 (7%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHE 58
            ++++W   QG    + V Y         L    DG++    + GL P + Y   +  LH+
Sbjct: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707

Query: 59   GKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118
                 PL    +T +           P  + L  T VT +SL   W  P      + +R 
Sbjct: 1708 DMESQPLIGTQSTAI-----------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR- 1755

Query: 119  GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTA 178
                   + P  +    +E+ +     S V+  L   T Y +++Y L+    +   QG  
Sbjct: 1756 -------VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1808

Query: 179  RTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQART 238
             TL  V   PR  + ++  ET+  ++W         F+V    A+G  P    +    R+
Sbjct: 1809 TTLENV-SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRS 1867

Query: 239  QKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQ 298
              + GL PG  Y++ + ++     S P+    +T  D P+ LR L  T    ++ W+PP+
Sbjct: 1868 YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1927

Query: 299  NPVDTYDVQVTAPGAPPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSP 353
              +  Y ++   PG+PP +      PG   +  +  L   T YT  V  L+    + P
Sbjct: 1928 ARITGYIIKYEKPGSPPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEP 1984



 Score = 96.7 bits (239), Expect = 6e-20
 Identities = 108/467 (23%), Positives = 188/467 (40%), Gaps = 38/467 (8%)

Query: 5    WSVAQGPFDSFVVQYEDT-NGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLG 63
            WS  Q P   + + Y  +  G    L +    + + +S L+P   Y   +Y + E +   
Sbjct: 831  WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890

Query: 64   PLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSP 123
            P+  +  T   P   T    R     L   +VT   + + W  P  A   +  R  V   
Sbjct: 891  PVVIQQETTGTPRSDTVPSPR----DLQFVEVTDVKVTIMWTPPESAVTGY--RVDVIPV 944

Query: 124  STLEPHPRPLLQRELMVPGTRHS-AVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLS 182
            +    H + L       P +R++ A +  L  G  Y   ++ +   H  +S   TA+  +
Sbjct: 945  NLPGEHGQRL-------PISRNTFAEVTGLSPGVTYYFKVFAVS--HGRESKPLTAQQTT 995

Query: 183  PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQ 242
              L++P +LQF    +++  V W PP ++   ++++  L   G+P+   V        L+
Sbjct: 996  K-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR 1054

Query: 243  GLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALN--LTEGFAVLHWKPPQNP 300
             L P + Y V++V+++G +ES   TG  TT+  G + +   N  +TE   V+ W P    
Sbjct: 1055 NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG-SSIPPYNTEVTETTIVITWTPAPRI 1113

Query: 301  VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLR-GPNLTSPASITFT 359
                 V+ +  G  P +  +   ++   +  L     Y  T++ LR G    +P      
Sbjct: 1114 GFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV 1171

Query: 360  TGLEAPRDLEAKEVTPRTALLT--W---TEPPVRPAGYLLSFHTPGGQ---NQEILLPGG 411
            T L  P +L   E  P T +LT  W   T P +   GY ++     GQ   + E ++   
Sbjct: 1172 TPLSPPTNLHL-EANPDTGVLTVSWERSTTPDI--TGYRITTTPTNGQQGNSLEEVVHAD 1228

Query: 412  ITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRD 458
             +S     L P   YN  +  +       P+S +       +P P D
Sbjct: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA---VPPPTD 1272


>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
          Length = 2421

 Score =  148 bits (373), Expect = 2e-35
 Identities = 118/479 (24%), Positives = 203/479 (42%), Gaps = 31/479 (6%)

Query: 3    LSWSVAQGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGK 60
            + W  +  P   + V     NG  P      G DQ+++ I GL+P+  Y   +Y  +   
Sbjct: 1651 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1710

Query: 61   RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
               PL     T +          RP+   L+ TDV   S+++ WE+P G    + + +  
Sbjct: 1711 ESQPLVQTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSS 1759

Query: 121  PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
            P     E  P P         G   +A L+ LR G+ Y++++  L    ++  + GT  T
Sbjct: 1760 PEDGIHELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1811

Query: 181  LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQ 239
              P   +P DL+F+++  TS    W PP  +   ++V     +   P + + +   + + 
Sbjct: 1812 AIP---APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868

Query: 240  KLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPP 297
             + GL+   +YEV+V +++    S P  G +TT+ +   P + R  + TE    + W+  
Sbjct: 1869 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1928

Query: 298  QNPVDTYDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASI 356
               +  + V  V A G  P+Q         Y +  L   T+Y   +  L     +SP  I
Sbjct: 1929 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988

Query: 357  TFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITS 414
              +T ++AP +L     TP + L++W  P  R  GY++ +  PG   +E++     G+T 
Sbjct: 1989 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048

Query: 415  HQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTS 473
              + GL P T Y   + A+       P+     T   + PF    G +  NG     TS
Sbjct: 2049 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-VQKTPFVTHPGYDTGNGIQLPGTS 2106



 Score =  129 bits (325), Expect = 7e-30
 Identities = 113/471 (23%), Positives = 197/471 (41%), Gaps = 39/471 (8%)

Query: 1    MRLSWSVAQG-PFDSFVVQYEDTNGQPQA--LLVDGDQSKILISGLEPSTPYRFLLYGLH 57
            MR++W+        +F+V+Y     +     L +    + ++++ L P T Y   +  ++
Sbjct: 1374 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1433

Query: 58   EGKRLGPLSAEGTTGL-APAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLL 116
            E     PL     TGL +P G            +  +D+T +S  ++W AP      + +
Sbjct: 1434 EQHESTPLRGRQKTGLDSPTG------------IDFSDITANSFTVHWIAPRATITGYRI 1481

Query: 117  RFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQG 176
            R     P      P     RE  VP +R+S  L +L  GT Y +++  L G  ++  + G
Sbjct: 1482 RH---HPEHFSGRP-----REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1533

Query: 177  TARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQ 235
               T+S V   PRDL+      TS  ++W  P      ++++Y    G  P Q   V G 
Sbjct: 1534 QQSTVSDV---PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1590

Query: 236  ARTQKLQGLIPGARYEVTVVSVRGFEE----SEPLTGFLTTVPDGPTQLRALNLTEGFAV 291
              T  + GL PG  Y +TV +V G  +    S+P++    T  D P+Q++  ++ +    
Sbjct: 1591 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1650

Query: 292  LHWKPPQNPVDTYDVQVTAPGAP-PLQAETPG-SAVDYPLHDLVLHTNYTATVRGLRGPN 349
            + W P  +PV  Y V  T    P P + +T G    +  +  L     Y  +V       
Sbjct: 1651 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1710

Query: 350  LTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL-- 407
             + P   T  T ++ P+ L   +V   +  + W  P  + + Y +++ +P     E+   
Sbjct: 1711 ESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1770

Query: 408  LPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRD 458
              G   + +L GL P + Y   + A+       P+  + +T    IP P D
Sbjct: 1771 PDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA---IPAPTD 1818



 Score =  119 bits (297), Expect = 1e-26
 Identities = 108/455 (23%), Positives = 184/455 (40%), Gaps = 28/455 (6%)

Query: 3    LSWSVAQGPFDSFVVQYEDTNGQP--QALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
            +SW         + + Y +T G    Q   V G +S   ISGL+P   Y   +Y +  G+
Sbjct: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGR 1615

Query: 61   RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
               P S++  +        +E  +P  SQ+ VTDV  +S+ + W         + +    
Sbjct: 1616 GDSPASSKPIS----INYRTEIDKP--SQMQVTDVQDNSISVKWLPSSSPVTGYRV---- 1665

Query: 121  PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
                T  P   P   +       +    +  L+    Y +++Y      ++  +  TA T
Sbjct: 1666 ----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721

Query: 181  LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQV-DGQARTQ 239
                ++ P+ L F+++   S K+ W  P  +   ++V+Y   + G  +     DG+  T 
Sbjct: 1722 ---NIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778

Query: 240  KLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQN 299
            +LQGL PG+ Y V+VV++    ES+PL G  +T    PT L+   +T       W PP  
Sbjct: 1779 ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNV 1838

Query: 300  PVDTYDVQVT--APGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASIT 357
             +  Y V+VT      P  +      +    +  L++ T Y  +V  L+    + PA   
Sbjct: 1839 QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV 1898

Query: 358  FTT--GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQN--QEILLPGGIT 413
             TT   +  PR     + T  T  ++W        G+ +      GQ   Q  + P  + 
Sbjct: 1899 VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKP-DVR 1957

Query: 414  SHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 448
            S+ + GL P T Y   L  +   +   PV    +T
Sbjct: 1958 SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992



 Score =  117 bits (294), Expect = 3e-26
 Identities = 115/480 (23%), Positives = 197/480 (41%), Gaps = 57/480 (11%)

Query: 3    LSWSVAQ-GPFDSFVVQYEDTN--GQPQALLVDGDQSKILISGLEPSTPYRFLL-----Y 54
            + W+  Q      +++++   N  G+ +   + G  +   I GL+P   Y   L     Y
Sbjct: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687

Query: 55   GLHEGKRLGPLSAEGTTGLAP---AGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAF 111
            G  E  R    +   +T +      G+T+  S    +  SVT++T SS  ++W +     
Sbjct: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747

Query: 112  DSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171
              F + + +      EP       + L +P T  S  + DL  G  Y + +Y +    + 
Sbjct: 748  SGFRVEYELSEEGD-EP-------QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQ 799

Query: 172  DSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQ 231
              I  T++T +P  ++P D    ++ +TS  V W  P +    +++ Y  +  G    + 
Sbjct: 800  SLILSTSQTTAP--DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857

Query: 232  VDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPL--------TGFLTTVPDGPTQLRAL 283
            +   A +  L  L PG +Y +T+ +V   +ES P+        T    TVP  P  L+ +
Sbjct: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP-SPRDLQFV 916

Query: 284  NLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVR 343
             +T+    + W PP++ V  Y V V     P    +            L +  N  A V 
Sbjct: 917  EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQR-----------LPISRNTFAEVT 965

Query: 344  GLRGPNLT--------------SPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRP 389
            GL  P +T               P +   TT L+AP +L+    T  T L+ WT P  + 
Sbjct: 966  GL-SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024

Query: 390  AGYLLSFH-TPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 448
             GY L+   T  GQ ++  +   ++ + L  L P++ Y   L A+ G    P  +  FTT
Sbjct: 1025 TGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084



 Score =  115 bits (287), Expect = 2e-25
 Identities = 99/406 (24%), Positives = 167/406 (41%), Gaps = 32/406 (7%)

Query: 31   VDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQL 90
            VD       ++GLEP   Y   +  L  G    P +    T + P            + L
Sbjct: 1316 VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPP-----------TDL 1364

Query: 91   SVTDVTTSSLRLNWEAPPGA-FDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVL 149
              T++   ++R+ W  PP     +FL+R+   SP   E         EL +  + ++ VL
Sbjct: 1365 RFTNIGPDTMRVTWAPPPSIDLTNFLVRY---SPVKNEEDVA-----ELSISPSDNAVVL 1416

Query: 150  RDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPP 209
             +L  GT Y +++  +   H++  ++G  +T    L+SP  + FS+I   S  V+W+ P 
Sbjct: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTGIDFSDITANSFTVHWIAPR 1473

Query: 210  SRADSFKVSYQLAD-GGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTG 268
            +    +++ +      G P+  +V     +  L  L PG  Y V++V++ G EES  L G
Sbjct: 1474 ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1533

Query: 269  FLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQV--TAPGAPPLQAETPGSAVD 326
              +TV D P  L  +  T    ++ W  P   V  Y +    T   +P  +   PGS   
Sbjct: 1534 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593

Query: 327  YPLHDLVLHTNYTATVRGLRG----PNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTW 382
              +  L    +YT TV  + G    P  + P SI + T ++ P  ++  +V   +  + W
Sbjct: 1594 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653

Query: 383  TEPPVRPAGYLLSFHTPGGQNQEILLPGG--ITSHQLLGLFPSTSY 426
                    GY ++     G         G   T   + GL P+  Y
Sbjct: 1654 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1699



 Score =  106 bits (264), Expect = 8e-23
 Identities = 83/358 (23%), Positives = 143/358 (39%), Gaps = 26/358 (7%)

Query: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHE 58
            ++++W   QG    + V Y         L    DG++    + GL P + Y   +  LH+
Sbjct: 1739 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1798

Query: 59   GKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118
                 PL    +T +           P  + L  T VT +SL   W  P      + +R 
Sbjct: 1799 DMESQPLIGTQSTAI-----------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR- 1846

Query: 119  GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTA 178
                   + P  +    +E+ +     S V+  L   T Y +++Y L+    +   QG  
Sbjct: 1847 -------VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1899

Query: 179  RTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQART 238
             TL  V   PR  + ++  ET+  ++W         F+V    A+G  P    +    R+
Sbjct: 1900 TTLENV-SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRS 1958

Query: 239  QKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQ 298
              + GL PG  Y++ + ++     S P+    +T  D P+ LR L  T    ++ W+PP+
Sbjct: 1959 YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 2018

Query: 299  NPVDTYDVQVTAPGAPPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSP 353
              +  Y ++   PG+PP +      PG   +  +  L   T YT  V  L+    + P
Sbjct: 2019 ARITGYIIKYEKPGSPPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEP 2075



 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 105/452 (23%), Positives = 183/452 (40%), Gaps = 35/452 (7%)

Query: 5    WSVAQGPFDSFVVQYEDT-NGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLG 63
            WS  Q P   + + Y  +  G    L +    + + +S L+P   Y   +Y + E +   
Sbjct: 831  WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890

Query: 64   PLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSP 123
            P+  +  T   P   T    R     L   +VT   + + W  P  A   +  R  V   
Sbjct: 891  PVVIQQETTGTPRSDTVPSPR----DLQFVEVTDVKVTIMWTPPESAVTGY--RVDVIPV 944

Query: 124  STLEPHPRPLLQRELMVPGTRHS-AVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLS 182
            +    H + L       P +R++ A +  L  G  Y   ++ +   H  +S   TA+  +
Sbjct: 945  NLPGEHGQRL-------PISRNTFAEVTGLSPGVTYYFKVFAVS--HGRESKPLTAQQTT 995

Query: 183  PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQ 242
              L++P +LQF    +++  V W PP ++   ++++  L   G+P+   V        L+
Sbjct: 996  K-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR 1054

Query: 243  GLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALN--LTEGFAVLHWKPPQNP 300
             L P + Y V++V+++G +ES   TG  TT+  G + +   N  +TE   V+ W P    
Sbjct: 1055 NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG-SSIPPYNTEVTETTIVITWTPAPRI 1113

Query: 301  VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLR-GPNLTSPASITFT 359
                 V+ +  G  P +  +   ++   +  L     Y  T++ LR G    +P      
Sbjct: 1114 GFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV 1171

Query: 360  TGLEAPRDLEAKEVTPRTALLT--W---TEPPVRPAGYLLSFHTPGGQ---NQEILLPGG 411
            T L  P +L   E  P T +LT  W   T P +   GY ++     GQ   + E ++   
Sbjct: 1172 TPLSPPTNLHL-EANPDTGVLTVSWERSTTPDI--TGYRITTTPTNGQQGNSLEEVVHAD 1228

Query: 412  ITSHQLLGLFPSTSYNARLQAMWGQSLLPPVS 443
             +S     L P   YN  +  +       P+S
Sbjct: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 101/440 (22%), Positives = 172/440 (39%), Gaps = 42/440 (9%)

Query: 24   GQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEES 83
            GQP+   V    SK  +  L+P++ Y   L  + +G +  P +    T L P       +
Sbjct: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQPGSSIPPYN 1095

Query: 84   RPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGT 143
                     T+VT +++ + W   P        + GV  PS     PR        V   
Sbjct: 1096 ---------TEVTETTIVITWTPAP----RIGFKLGV-RPSQGGEAPRE-------VTSD 1134

Query: 144  RHSAVLRDLRSGTLYSLTLYGLRGPHKADS--IQGTARTLSPVLESPRDLQFSEIRETSA 201
              S V+  L  G  Y  T+  LR   + D+  +      LSP    P +L      +T  
Sbjct: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP----PTNLHLEANPDTGV 1190

Query: 202  -KVNWMPPPSR-ADSFKVSYQLADGGEPQSVQ--VDGQARTQKLQGLIPGARYEVTVVSV 257
              V+W    +     ++++    +G +  S++  V     +     L PG  Y V+V +V
Sbjct: 1191 LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250

Query: 258  RGFEESEPLTGFLTTVPDGP--TQLRALNLTEGFAVLHWKP-PQNPVDTYDVQVTAPGA- 313
            +  +ES P++   T +P+ P  T L  +++T+    L W P   + +  Y + V A G  
Sbjct: 1251 KDDKESVPISD--TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEG 1308

Query: 314  -PPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKE 372
             P  +     S   Y +  L    +Y  +V  L     ++P ++T  T +  P DL    
Sbjct: 1309 IPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTN 1368

Query: 373  VTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQ---EILLPGGITSHQLLGLFPSTSYNAR 429
            + P T  +TW  PP       L  ++P    +   E+ +     +  L  L P T Y   
Sbjct: 1369 IGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVS 1428

Query: 430  LQAMWGQSLLPPVSTSFTTG 449
            + +++ Q    P+     TG
Sbjct: 1429 VSSVYEQHESTPLRGRQKTG 1448


>gi|5730075 fibrinogen-like 2 precursor [Homo sapiens]
          Length = 439

 Score =  148 bits (373), Expect = 2e-35
 Identities = 83/233 (35%), Positives = 124/233 (53%), Gaps = 27/233 (11%)

Query: 457 RDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWE 516
           +DC +    G  +S T  +  +  +     V+CDMET GGGW V Q R+DG T+F R W+
Sbjct: 211 KDCSDYYAIGKRSSETYRVTPDP-KNSSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQ 269

Query: 517 DYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLR-AGDEAVFAQYDSFHVDSAAEYYR 575
           DY  GFGN+  EFWLGN+ +H LT++ +  +R+DL       ++A YD F+V +    YR
Sbjct: 270 DYKAGFGNLRREFWLGNDKIHLLTKSKEMILRIDLEDFNGVELYALYDQFYVANEFLKYR 329

Query: 576 LHLEGYHGTAGDSMSY-----HSGSVFSARDRDPNSLLI-SCAVSYRGAWWYRNCHYANL 629
           LH+  Y+GTAGD++ +     H    F+  D+D +     +C + Y   WW+  C  ANL
Sbjct: 330 LHVGNYNGTAGDALRFNKHYNHDLKFFTTPDKDNDRYPSGNCGLYYSSGWWFDACLSANL 389

Query: 630 NGLYGSTVDHQ-------GVSWYHWK--------GFEFSVPFTEMKLRPRNFR 667
           NG Y     HQ       G+ W  W         G++ S    +M +RP++F+
Sbjct: 390 NGKY----YHQKYRGVRNGIFWGTWPGVSEAHPGGYKSSFKEAKMMIRPKHFK 438


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,245,765
Number of Sequences: 37866
Number of extensions: 1573178
Number of successful extensions: 5775
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 133
Number of HSP's that attempted gapping in prelim test: 3658
Number of HSP's gapped (non-prelim): 1116
length of query: 673
length of database: 18,247,518
effective HSP length: 109
effective length of query: 564
effective length of database: 14,120,124
effective search space: 7963749936
effective search space used: 7963749936
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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