Search of human proteins with 20631958

Search of human proteins with 20631958

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20631958 BCL2-associated X protein isoform alpha [Homo
sapiens]
         (192 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20631958 BCL2-associated X protein isoform alpha [Homo sapiens]    391   e-109
gi|242117893 BCL2-associated X protein isoform sigma [Homo sapiens]   352   8e-98
gi|4757838 BCL2-associated X protein isoform beta [Homo sapiens]      323   7e-89
gi|20631964 BCL2-associated X protein isoform delta [Homo sapiens]    268   2e-72
gi|72198189 B-cell lymphoma protein 2 alpha isoform [Homo sapiens]     63   1e-10
gi|20336335 BCL2-like 1 isoform 1 [Homo sapiens]                       62   3e-10
gi|72198346 B-cell lymphoma protein 2 beta isoform [Homo sapiens]      60   1e-09
gi|11386165 myeloid cell leukemia sequence 1 isoform 1 [Homo sap...    58   4e-09
gi|4757842 BCL2-like 2 protein [Homo sapiens]                          57   7e-09
gi|14210524 BCL2-related ovarian killer [Homo sapiens]                 57   1e-08
gi|239751987 PREDICTED: hypothetical protein XP_002348091 [Homo ...    56   2e-08
gi|4502363 BCL2-antagonist/killer 1 [Homo sapiens]                     54   6e-08
gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens]            54   8e-08
gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens]          51   7e-07
gi|9966783 BCL2-like 10 (apoptosis facilitator) [Homo sapiens]         39   0.002
gi|21040330 BCL2-like 14 isoform 1 [Homo sapiens]                      34   0.087
gi|21040328 BCL2-like 14 isoform 1 [Homo sapiens]                      34   0.087
gi|195947374 claudin 5 [Homo sapiens]                                  31   0.57 
gi|195947372 claudin 5 [Homo sapiens]                                  31   0.57 
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     30   1.6  
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     30   1.6  
gi|7657058 eukaryotic translation initiation factor 2B, subunit ...    30   1.6  
gi|6005830 plakophilin 3 [Homo sapiens]                                29   2.2  
gi|189303549 speedy homolog E4 [Homo sapiens]                          29   2.8  
gi|73623035 sperm associated antigen 5 [Homo sapiens]                  28   6.3  
gi|183979973 claudin 19 isoform a [Homo sapiens]                       27   8.2  
gi|183979975 claudin 19 isoform b [Homo sapiens]                       27   8.2  
gi|66730423 hypothetical protein LOC389384 [Homo sapiens]              27   8.2  

>gi|20631958 BCL2-associated X protein isoform alpha [Homo sapiens]
          Length = 192

 Score =  391 bits (1004), Expect = e-109
 Identities = 192/192 (100%), Positives = 192/192 (100%)

Query: 1   MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60
           MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
Sbjct: 1   MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60

Query: 61  ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120
           ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
Sbjct: 61  ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120

Query: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV 180
           VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV
Sbjct: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV 180

Query: 181 LTASLTIWKKMG 192
           LTASLTIWKKMG
Sbjct: 181 LTASLTIWKKMG 192


>gi|242117893 BCL2-associated X protein isoform sigma [Homo sapiens]
          Length = 179

 Score =  352 bits (904), Expect = 8e-98
 Identities = 179/192 (93%), Positives = 179/192 (93%), Gaps = 13/192 (6%)

Query: 1   MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60
           MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
Sbjct: 1   MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60

Query: 61  ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120
           ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
Sbjct: 61  ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120

Query: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV 180
           VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGW             TVTIFVAGV
Sbjct: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGW-------------TVTIFVAGV 167

Query: 181 LTASLTIWKKMG 192
           LTASLTIWKKMG
Sbjct: 168 LTASLTIWKKMG 179


>gi|4757838 BCL2-associated X protein isoform beta [Homo sapiens]
          Length = 218

 Score =  323 bits (827), Expect = 7e-89
 Identities = 160/162 (98%), Positives = 160/162 (98%)

Query: 1   MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60
           MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
Sbjct: 1   MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60

Query: 61  ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120
           ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
Sbjct: 61  ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120

Query: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLL 162
           VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGW  LL
Sbjct: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLL 162


>gi|20631964 BCL2-associated X protein isoform delta [Homo sapiens]
          Length = 143

 Score =  268 bits (686), Expect = 2e-72
 Identities = 142/192 (73%), Positives = 142/192 (73%), Gaps = 49/192 (25%)

Query: 1   MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60
           MDGSGEQPRGGGPTSSEQIMKTGALLL                                 
Sbjct: 1   MDGSGEQPRGGGPTSSEQIMKTGALLL--------------------------------- 27

Query: 61  ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120
                           Q MIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
Sbjct: 28  ----------------QGMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 71

Query: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV 180
           VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV
Sbjct: 72  VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV 131

Query: 181 LTASLTIWKKMG 192
           LTASLTIWKKMG
Sbjct: 132 LTASLTIWKKMG 143


>gi|72198189 B-cell lymphoma protein 2 alpha isoform [Homo sapiens]
          Length = 239

 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 41/133 (30%), Positives = 63/133 (47%), Gaps = 14/133 (10%)

Query: 40  GEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTD------SPREVFF 93
           G A   AL PVP           L++ GD  D +   +R  A + +       + R  F 
Sbjct: 79  GAAAGPALSPVPPVVHLT-----LRQAGD--DFSRRYRRDFAEMSSQLHLTPFTARGRFA 131

Query: 94  RVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQ 153
            V  ++F DG  NWGR+VA F F   + ++++  ++  L+  I  W  ++L   L  WIQ
Sbjct: 132 TVVEELFRDG-VNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQ 190

Query: 154 DQGGWDGLLSYFG 166
           D GGWD  +  +G
Sbjct: 191 DNGGWDAFVELYG 203


>gi|20336335 BCL2-like 1 isoform 1 [Homo sapiens]
          Length = 233

 Score = 62.0 bits (149), Expect = 3e-10
 Identities = 36/116 (31%), Positives = 57/116 (49%), Gaps = 13/116 (11%)

Query: 59  LSECLKRIGDELDSNMELQRMIAAVDTDSPREV--------FFRVAADMFSDGNFNWGRV 110
           + + L+  GDE     EL+   A  D  S   +        F +V  ++F DG  NWGR+
Sbjct: 86  VKQALREAGDEF----ELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRI 140

Query: 111 VALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFG 166
           VA F F   L ++++  ++  L+  I  W   +L + L  WIQ+ GGWD  +  +G
Sbjct: 141 VAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG 196


>gi|72198346 B-cell lymphoma protein 2 beta isoform [Homo sapiens]
          Length = 205

 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 41/129 (31%), Positives = 61/129 (47%), Gaps = 14/129 (10%)

Query: 40  GEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTD------SPREVFF 93
           G A   AL PVP           L++ GD  D +   +R  A + +       + R  F 
Sbjct: 79  GAAAGPALSPVPPVVHLT-----LRQAGD--DFSRRYRRDFAEMSSQLHLTPFTARGRFA 131

Query: 94  RVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQ 153
            V  ++F DG  NWGR+VA F F   + ++++  ++  L+  I  W  ++L   L  WIQ
Sbjct: 132 TVVEELFRDG-VNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQ 190

Query: 154 DQGGWDGLL 162
           D GGW G L
Sbjct: 191 DNGGWVGAL 199


>gi|11386165 myeloid cell leukemia sequence 1 isoform 1 [Homo
           sapiens]
          Length = 350

 Score = 58.2 bits (139), Expect = 4e-09
 Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 4/116 (3%)

Query: 54  ASTKKLSECLKRIGDELDSNME--LQRMIAAVDTDSPREV--FFRVAADMFSDGNFNWGR 109
           A+++K  E L+R+GD +  N E   Q M+  +D  +  +V    RV   +FSDG  NWGR
Sbjct: 204 ATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGR 263

Query: 110 VVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYF 165
           +V L  F + +            I  +     D L      W+  Q GWDG + +F
Sbjct: 264 IVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFF 319


>gi|4757842 BCL2-like 2 protein [Homo sapiens]
          Length = 193

 Score = 57.4 bits (137), Expect = 7e-09
 Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 16/131 (12%)

Query: 40  GEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAA----VDTDSPREVFFRV 95
           GE P  A DP         L + ++  GDE ++         A    V   S ++ F +V
Sbjct: 34  GEGP--AADP---------LHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQV 82

Query: 96  AADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQ 155
           + ++F  G  NWGR+VA F F + L  +++  ++  L+  +  W + +L  RL  WI   
Sbjct: 83  SDELFQGGP-NWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETRLADWIHSS 141

Query: 156 GGWDGLLSYFG 166
           GGW    + +G
Sbjct: 142 GGWAEFTALYG 152


>gi|14210524 BCL2-related ovarian killer [Homo sapiens]
          Length = 212

 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 46/159 (28%), Positives = 76/159 (47%), Gaps = 14/159 (8%)

Query: 13  PTSSEQIMKTGALLLQGFIQDRAGRMG--GEAPELALDPVPQDASTKKLSECLKRIGDEL 70
           PT  E + +  AL  + ++  R  R G    APE A  PVP      ++   L R+GDEL
Sbjct: 22  PTDKELVAQAKALGRE-YVHARLLRAGLSWSAPERAA-PVP--GRLAEVCAVLLRLGDEL 77

Query: 71  DS-------NMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLK 123
           +        N+  Q  I+        + F  VA  +FS G   WG+VV+L+  A+ L + 
Sbjct: 78  EMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSAG-ITWGKVVSLYAVAAGLAVD 136

Query: 124 ALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLL 162
            +    P ++  ++    +F+R+ L  W++ +GGW  +L
Sbjct: 137 CVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVL 175


>gi|239751987 PREDICTED: hypothetical protein XP_002348091 [Homo
           sapiens]
          Length = 211

 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 37/149 (24%), Positives = 69/149 (46%), Gaps = 6/149 (4%)

Query: 32  QDRAGRMGGEAPELALDPVPQDASTKKLSECLKRIGDELDS--NMELQRMIAAVD--TDS 87
           Q+  G      PE+   P+   ++  ++   L  IGD+++   + E Q M+  +    ++
Sbjct: 47  QEAEGAAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAEN 106

Query: 88  PREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRER 147
             E F ++A+ +F  G  NWGRVVAL  F+ +L L      +   +  +  + +DF+   
Sbjct: 107 AYEYFTKIASSLFESG-INWGRVVALLGFSYRLALHIYQRGLTGFLGQVTRFVVDFMLHH 165

Query: 148 LLG-WIQDQGGWDGLLSYFGTPTWQTVTI 175
            +  WI  +GGW   L+    P    + +
Sbjct: 166 CIARWIAQRGGWVAALNLGNGPILNVLVV 194


>gi|4502363 BCL2-antagonist/killer 1 [Homo sapiens]
          Length = 211

 Score = 54.3 bits (129), Expect = 6e-08
 Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 6/149 (4%)

Query: 32  QDRAGRMGGEAPELALDPVPQDASTKKLSECLKRIGDELDS--NMELQRMIAAVD--TDS 87
           Q+  G      PE+   P+   ++  ++   L  IGD+++   + E Q M+  +    ++
Sbjct: 47  QEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAEN 106

Query: 88  PREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRER 147
             E F ++A  +F  G  NWGRVVAL  F  +L L      +   +  +  + +DF+   
Sbjct: 107 AYEYFTKIATSLFESG-INWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHH 165

Query: 148 LLG-WIQDQGGWDGLLSYFGTPTWQTVTI 175
            +  WI  +GGW   L+    P    + +
Sbjct: 166 CIARWIAQRGGWVAALNLGNGPILNVLVV 194


>gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens]
          Length = 175

 Score = 53.9 bits (128), Expect = 8e-08
 Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 10/151 (6%)

Query: 50  VPQDAS-TKKLSECLKRIGDELDSNMELQRM-----IAAVDTDSPREVFFRVAADMFSDG 103
           +PQ  S   K S  L+ +   +   +E         +  V  D+ R +F +V    F DG
Sbjct: 23  IPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDG 82

Query: 104 NFNWGRVVALFYFASKLVLKALCTKVP---ELIRTIMGWTLDFLRERLLGWIQDQGGWD- 159
             NWGR+V +F F   L+ K L  ++    +  + I  +  +F+      WI+  GGW+ 
Sbjct: 83  IINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWEN 142

Query: 160 GLLSYFGTPTWQTVTIFVAGVLTASLTIWKK 190
           G +  F   +     + V G +   L++ K+
Sbjct: 143 GFVKKFEPKSGWMTFLEVTGKICEMLSLLKQ 173


>gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens]
          Length = 163

 Score = 50.8 bits (120), Expect = 7e-07
 Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 9/118 (7%)

Query: 50  VPQDAS-TKKLSECLKRIGDELDSNMELQRM-----IAAVDTDSPREVFFRVAADMFSDG 103
           +PQ  S   K S  L+ +   +   +E         +  V  D+ R +F +V    F DG
Sbjct: 23  IPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDG 82

Query: 104 NFNWGRVVALFYFASKLVLKALCTKVP---ELIRTIMGWTLDFLRERLLGWIQDQGGW 158
             NWGR+V +F F   L+ K L  ++    +  + I  +  +F+      WI+  GGW
Sbjct: 83  IINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGW 140


>gi|9966783 BCL2-like 10 (apoptosis facilitator) [Homo sapiens]
          Length = 204

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 25/110 (22%)

Query: 107 WGRVVALFYFASKLVLKALCTKV--------PELIRTIMGWTLD------FLRERLLG-- 150
           WGRVV L  FA  L+ +              P L         D       L  RL+G  
Sbjct: 94  WGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQH 153

Query: 151 --WIQDQGGWDGLLSYFGTP----TW--QTVTIFVAGVL-TASLTIWKKM 191
             W+Q QGGWDG   +F TP     W  Q V  F++ +L TA + +W ++
Sbjct: 154 RAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRL 203


>gi|21040330 BCL2-like 14 isoform 1 [Homo sapiens]
          Length = 327

 Score = 33.9 bits (76), Expect = 0.087
 Identities = 27/110 (24%), Positives = 48/110 (43%), Gaps = 6/110 (5%)

Query: 58  KLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRV-VALFYF 116
           K+ E LK  GD+L+  ++  + +     D      F+   D    G    G   V    F
Sbjct: 211 KIVELLKYSGDQLERKLKKDKALMGHFQDGLSYSVFKTITDQVLMGVDPRGESEVKAQGF 270

Query: 117 ASKLVLKALCTKVPEL----IRTIMGWTLDFLRERLLGWIQDQGGWDGLL 162
            + LV+  +  K+  +    +  ++G+   +L+E    WIQ  GGW+ +L
Sbjct: 271 KAALVID-VTAKLTAIDNHPMNRVLGFGTKYLKENFSPWIQQHGGWEKIL 319


>gi|21040328 BCL2-like 14 isoform 1 [Homo sapiens]
          Length = 327

 Score = 33.9 bits (76), Expect = 0.087
 Identities = 27/110 (24%), Positives = 48/110 (43%), Gaps = 6/110 (5%)

Query: 58  KLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRV-VALFYF 116
           K+ E LK  GD+L+  ++  + +     D      F+   D    G    G   V    F
Sbjct: 211 KIVELLKYSGDQLERKLKKDKALMGHFQDGLSYSVFKTITDQVLMGVDPRGESEVKAQGF 270

Query: 117 ASKLVLKALCTKVPEL----IRTIMGWTLDFLRERLLGWIQDQGGWDGLL 162
            + LV+  +  K+  +    +  ++G+   +L+E    WIQ  GGW+ +L
Sbjct: 271 KAALVID-VTAKLTAIDNHPMNRVLGFGTKYLKENFSPWIQQHGGWEKIL 319


>gi|195947374 claudin 5 [Homo sapiens]
          Length = 303

 Score = 31.2 bits (69), Expect = 0.57
 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)

Query: 148 LLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTASLTIWK 189
           +LG +    GW GL+   G P WQ VT F+   +  + T WK
Sbjct: 93  ILGLVLCLVGWGGLILACGLPMWQ-VTAFLDHNIVTAQTTWK 133


>gi|195947372 claudin 5 [Homo sapiens]
          Length = 303

 Score = 31.2 bits (69), Expect = 0.57
 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)

Query: 148 LLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTASLTIWK 189
           +LG +    GW GL+   G P WQ VT F+   +  + T WK
Sbjct: 93  ILGLVLCLVGWGGLILACGLPMWQ-VTAFLDHNIVTAQTTWK 133


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 29.6 bits (65), Expect = 1.6
 Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 7/64 (10%)

Query: 3   GSGEQPRGGG---PTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKL 59
           GSG     G    P+SS     + +     F Q R G MGG  P  A    PQ  +T  L
Sbjct: 240 GSGAAAAAGSKPPPSSSASASSSSS----SFAQQRFGAMGGGGPSAAGGGTPQPTATPTL 295

Query: 60  SECL 63
           ++ L
Sbjct: 296 NQLL 299


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 29.6 bits (65), Expect = 1.6
 Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 7/64 (10%)

Query: 3   GSGEQPRGGG---PTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKL 59
           GSG     G    P+SS     + +     F Q R G MGG  P  A    PQ  +T  L
Sbjct: 240 GSGAAAAAGSKPPPSSSASASSSSS----SFAQQRFGAMGGGGPSAAGGGTPQPTATPTL 295

Query: 60  SECL 63
           ++ L
Sbjct: 296 NQLL 299


>gi|7657058 eukaryotic translation initiation factor 2B, subunit 2
          beta, 39kDa [Homo sapiens]
          Length = 351

 Score = 29.6 bits (65), Expect = 1.6
 Identities = 16/37 (43%), Positives = 20/37 (54%)

Query: 9  RGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPEL 45
          RGGGP SSE++ +    LL+  I D      GE  EL
Sbjct: 24 RGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMEL 60


>gi|6005830 plakophilin 3 [Homo sapiens]
          Length = 797

 Score = 29.3 bits (64), Expect = 2.2
 Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 10/106 (9%)

Query: 3   GSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGR-MGGEAPELALDPVPQDASTKKLSE 61
           G  + P     + S  I       LQ F      R +GG  P   L+PV +  S + LS 
Sbjct: 227 GGLDWPEATEVSPSRTIRAPAVRTLQRFQSSHRSRGVGGAVPGAVLEPVARAPSVRSLSL 286

Query: 62  CLKRIG--------DELDSNMELQRMIAAV-DTDSPREVFFRVAAD 98
            L   G        +   S+  LQR+ +   D D P  V + +A+D
Sbjct: 287 SLADSGHLPDVHGFNSYGSHRTLQRLSSGFDDIDLPSAVKYLMASD 332


>gi|189303549 speedy homolog E4 [Homo sapiens]
          Length = 237

 Score = 28.9 bits (63), Expect = 2.8
 Identities = 16/47 (34%), Positives = 22/47 (46%)

Query: 39 GGEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDT 85
          G  AP +   P PQ    K+ SE      +EL+  +EL+R     DT
Sbjct: 34 GPSAPWIDPSPQPQSLGLKRKSEWSDESEEELEEELELERAPEPEDT 80


>gi|73623035 sperm associated antigen 5 [Homo sapiens]
          Length = 1193

 Score = 27.7 bits (60), Expect = 6.3
 Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 41  EAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMF 100
           E+ E  LDP+PQ +ST K SE      D L + M    ++        +++ F    D  
Sbjct: 96  ESDEQPLDPIPQISSTPKTSE---EAVDPLGNYMVKTIVLVPSPLGQQQDMIFEARLDTM 152

Query: 101 SDGN 104
           ++ N
Sbjct: 153 AETN 156


>gi|183979973 claudin 19 isoform a [Homo sapiens]
          Length = 224

 Score = 27.3 bits (59), Expect = 8.2
 Identities = 11/37 (29%), Positives = 20/37 (54%)

Query: 147 RLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTA 183
           +LLG+    GGW G+++    P W+  +     ++TA
Sbjct: 7   QLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITA 43


>gi|183979975 claudin 19 isoform b [Homo sapiens]
          Length = 211

 Score = 27.3 bits (59), Expect = 8.2
 Identities = 11/37 (29%), Positives = 20/37 (54%)

Query: 147 RLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTA 183
           +LLG+    GGW G+++    P W+  +     ++TA
Sbjct: 7   QLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITA 43


>gi|66730423 hypothetical protein LOC389384 [Homo sapiens]
          Length = 652

 Score = 27.3 bits (59), Expect = 8.2
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 12/73 (16%)

Query: 9   RGGGPTSSEQ-----IMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSECL 63
           R GG  S  Q     +  TGAL       D +    G   E  L    QDA  + + E L
Sbjct: 202 RRGGEDSDHQSFLIKVDGTGAL-------DVSPHATGHQQEEELKKPDQDAIIQMIVELL 254

Query: 64  KRIGDELDSNMEL 76
           KR+GD+ +    L
Sbjct: 255 KRVGDQWEEEQSL 267


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,364,191
Number of Sequences: 37866
Number of extensions: 312586
Number of successful extensions: 690
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 656
Number of HSP's gapped (non-prelim): 30
length of query: 192
length of database: 18,247,518
effective HSP length: 97
effective length of query: 95
effective length of database: 14,574,516
effective search space: 1384579020
effective search space used: 1384579020
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.