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Search of human proteins with 20270303
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20270303 ras homolog gene family, member T2 [Homo sapiens]
(618 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20270303 ras homolog gene family, member T2 [Homo sapiens] 1251 0.0
gi|75750470 ras homolog gene family, member T1 isoform 3 [Homo s... 749 0.0
gi|75750476 ras homolog gene family, member T1 isoform 2 [Homo s... 729 0.0
gi|75750480 ras homolog gene family, member T1 isoform 1 [Homo s... 716 0.0
gi|4757764 ras homolog gene family, member B [Homo sapiens] 70 4e-12
gi|38016957 ras homolog gene family, member F [Homo sapiens] 67 4e-11
gi|46249393 ras homolog gene family, member G [Homo sapiens] 66 8e-11
gi|10835049 ras homolog gene family, member A [Homo sapiens] 65 1e-10
gi|111494251 ras homolog gene family, member C precursor [Homo s... 65 2e-10
gi|111494248 ras homolog gene family, member C precursor [Homo s... 65 2e-10
gi|28395033 ras homolog gene family, member C precursor [Homo sa... 65 2e-10
gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens] 64 3e-10
gi|50263042 ras-like protein TC10 [Homo sapiens] 63 7e-10
gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens] 63 9e-10
gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens] 63 9e-10
gi|7656900 ras homolog D [Homo sapiens] 63 9e-10
gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi... 62 2e-09
gi|11034843 ras homolog gene family, member U [Homo sapiens] 62 2e-09
gi|229577148 ras homolog gene family, member V [Homo sapiens] 61 3e-09
gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra... 61 3e-09
gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens] 60 5e-09
gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil... 60 6e-09
gi|4758996 Ras-related protein Rab-33A [Homo sapiens] 58 2e-08
gi|40255119 RAS and EF-hand domain containing [Homo sapiens] 57 4e-08
gi|4885069 ras homolog gene family, member E [Homo sapiens] 57 5e-08
gi|16903164 ras homolog gene family, member J [Homo sapiens] 56 9e-08
gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens] 55 2e-07
gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Ra... 54 3e-07
gi|4885581 Rho family GTPase 2 [Homo sapiens] 53 9e-07
gi|4757770 ras homolog gene family, member H [Homo sapiens] 52 2e-06
>gi|20270303 ras homolog gene family, member T2 [Homo sapiens]
Length = 618
Score = 1251 bits (3238), Expect = 0.0
Identities = 618/618 (100%), Positives = 618/618 (100%)
Query: 1 MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSE 60
MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSE
Sbjct: 1 MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSE 60
Query: 61 AEQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKS 120
AEQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKS
Sbjct: 61 AEQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKS 120
Query: 121 DLRSGSSMEAVLPIMSQFPEIETCVECSAKNLRNISELFYYAQKAVLHPTAPLYDPEAKQ 180
DLRSGSSMEAVLPIMSQFPEIETCVECSAKNLRNISELFYYAQKAVLHPTAPLYDPEAKQ
Sbjct: 121 DLRSGSSMEAVLPIMSQFPEIETCVECSAKNLRNISELFYYAQKAVLHPTAPLYDPEAKQ 180
Query: 181 LRPACAQALTRIFRLSDQDLDQALSDEELNAFQKSCFGHPLAPQALEDVKTVVCRNVAGG 240
LRPACAQALTRIFRLSDQDLDQALSDEELNAFQKSCFGHPLAPQALEDVKTVVCRNVAGG
Sbjct: 181 LRPACAQALTRIFRLSDQDLDQALSDEELNAFQKSCFGHPLAPQALEDVKTVVCRNVAGG 240
Query: 241 VREDRLTLDGFLFLNTLFIQRGRHETTWTILRRFGYSDALELTADYLSPLIHVPPGCSTE 300
VREDRLTLDGFLFLNTLFIQRGRHETTWTILRRFGYSDALELTADYLSPLIHVPPGCSTE
Sbjct: 241 VREDRLTLDGFLFLNTLFIQRGRHETTWTILRRFGYSDALELTADYLSPLIHVPPGCSTE 300
Query: 301 LNHLGYQFVQRVFEKHDQDRDGALSPVELQSLFSVFPAAPWGPELPRTVRTEAGRLPLHG 360
LNHLGYQFVQRVFEKHDQDRDGALSPVELQSLFSVFPAAPWGPELPRTVRTEAGRLPLHG
Sbjct: 301 LNHLGYQFVQRVFEKHDQDRDGALSPVELQSLFSVFPAAPWGPELPRTVRTEAGRLPLHG 360
Query: 361 YLCQWTLVTYLDVRSCLGHLGYLGYPTLCEQDQAHAITVTREKRLDQEKGQTQRSVLLCK 420
YLCQWTLVTYLDVRSCLGHLGYLGYPTLCEQDQAHAITVTREKRLDQEKGQTQRSVLLCK
Sbjct: 361 YLCQWTLVTYLDVRSCLGHLGYLGYPTLCEQDQAHAITVTREKRLDQEKGQTQRSVLLCK 420
Query: 421 VVGARGVGKSAFLQAFLGRGLGHQDTREQPPGYAIDTVQVNGQEKYLILCEVGTDGLLAT 480
VVGARGVGKSAFLQAFLGRGLGHQDTREQPPGYAIDTVQVNGQEKYLILCEVGTDGLLAT
Sbjct: 421 VVGARGVGKSAFLQAFLGRGLGHQDTREQPPGYAIDTVQVNGQEKYLILCEVGTDGLLAT 480
Query: 481 SLDATCDVACLMFDGSDPKSFAHCASVYKHHYMDGQTPCLFVSSKADLPEGVAVSGPSPA 540
SLDATCDVACLMFDGSDPKSFAHCASVYKHHYMDGQTPCLFVSSKADLPEGVAVSGPSPA
Sbjct: 481 SLDATCDVACLMFDGSDPKSFAHCASVYKHHYMDGQTPCLFVSSKADLPEGVAVSGPSPA 540
Query: 541 EFCRKHRLPAPVPFSCAGPAEPSTTIFTQLATMAAFPHLVHAELHPSSFWLRGLLGVVGA 600
EFCRKHRLPAPVPFSCAGPAEPSTTIFTQLATMAAFPHLVHAELHPSSFWLRGLLGVVGA
Sbjct: 541 EFCRKHRLPAPVPFSCAGPAEPSTTIFTQLATMAAFPHLVHAELHPSSFWLRGLLGVVGA 600
Query: 601 AVAAVLSFSLYRVLVKSQ 618
AVAAVLSFSLYRVLVKSQ
Sbjct: 601 AVAAVLSFSLYRVLVKSQ 618
>gi|75750470 ras homolog gene family, member T1 isoform 3 [Homo
sapiens]
Length = 618
Score = 749 bits (1934), Expect = 0.0
Identities = 372/622 (59%), Positives = 468/622 (75%), Gaps = 8/622 (1%)
Query: 1 MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSE 60
M++DVRILL+GE +VGKTSLI+SLV EEFPEEVPPRAEEITIPADVTPE+VPTHIVDYSE
Sbjct: 1 MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
Query: 61 AEQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKS 120
AEQ+DE+L +EI +ANV+C+VY V+ + +I+K+ ++WIPL+N T + R+P+ILVGNKS
Sbjct: 61 AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
Query: 121 DLRSGSSMEAVLPIMSQFPEIETCVECSAKNLRNISELFYYAQKAVLHPTAPLYDPEAKQ 180
DL SSME +LPIM+Q+ EIETCVECSAKNL+NISELFYYAQKAVLHPT PLY PE K+
Sbjct: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
Query: 181 LRPACAQALTRIFRLSDQDLDQALSDEELNAFQKSCFGHPLAPQALEDVKTVVCRNVAGG 240
++PAC +ALTRIF++SDQD D L+D ELN FQ+ CF PLAPQALEDVK VV ++++ G
Sbjct: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
Query: 241 VREDRLTLDGFLFLNTLFIQRGRHETTWTILRRFGYSDALELTADYLSPLIHVPPGCSTE 300
V + LTL GFLFL+TLFIQRGRHETTWT+LRRFGY D L+LT +YL PL+ +PP C+TE
Sbjct: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
Query: 301 LNHLGYQFVQRVFEKHDQDRDGALSPVELQSLFSVFPAAPWGPELPRTVRT-EAGRLPLH 359
LNH Y F+Q F+KHD DRD ALSP EL+ LF VFP PWGP++ TV T E G +
Sbjct: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
Query: 360 GYLCQWTLVTYLDVRSCLGHLGYLGYPTLCEQD-QAHAITVTREKRLDQEKGQTQRSVLL 418
G+L QWTL TYLDV+ CL +LGYLGY L EQ+ QA A+TVTR+K++D +K QTQR+V
Sbjct: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
Query: 419 CKVVGARGVGKSAFLQAFLGRGLGHQD--TREQPPGYAIDTVQVNGQEKYLILCEVGTDG 476
C V+G + GKS LQA LGR L Q + YAI+TV V GQEKYL+L ++
Sbjct: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
Query: 477 LLATSLDATCDVACLMFDGSDPKSFAHCASVYKHHYMDGQTPCLFVSSKADLPEGVAVSG 536
L T + CDV CL++D S+PKSF +CA ++K H+MD + PCL V++K+DL E
Sbjct: 481 FL-TEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYS 539
Query: 537 PSPAEFCRKHRLPAPVPFSCAGPAEPSTTIFTQLATMAAFPHLVHAELHPSSFWLRGLLG 596
SP +FCRKH++P P F+C PS IF +L TMA +PH+ A+L S+FWLR
Sbjct: 540 ISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASF- 598
Query: 597 VVGAAVAAVLSFSLYRVLVKSQ 618
GA V AVL F++Y+ L+K +
Sbjct: 599 --GATVFAVLGFAMYKALLKQR 618
>gi|75750476 ras homolog gene family, member T1 isoform 2 [Homo
sapiens]
Length = 659
Score = 729 bits (1882), Expect = 0.0
Identities = 372/663 (56%), Positives = 468/663 (70%), Gaps = 49/663 (7%)
Query: 1 MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSE 60
M++DVRILL+GE +VGKTSLI+SLV EEFPEEVPPRAEEITIPADVTPE+VPTHIVDYSE
Sbjct: 1 MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
Query: 61 AEQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKS 120
AEQ+DE+L +EI +ANV+C+VY V+ + +I+K+ ++WIPL+N T + R+P+ILVGNKS
Sbjct: 61 AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
Query: 121 DLRSGSSMEAVLPIMSQFPEIETCVECSAKNLRNISELFYYAQKAVLHPTAPLYDPEAKQ 180
DL SSME +LPIM+Q+ EIETCVECSAKNL+NISELFYYAQKAVLHPT PLY PE K+
Sbjct: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
Query: 181 LRPACAQALTRIFRLSDQDLDQALSDEELNAFQKSCFGHPLAPQALEDVKTVVCRNVAGG 240
++PAC +ALTRIF++SDQD D L+D ELN FQ+ CF PLAPQALEDVK VV ++++ G
Sbjct: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
Query: 241 VREDRLTLDGFLFLNTLFIQRGRHETTWTILRRFGYSDALELTADYLSPLIHVPPGCSTE 300
V + LTL GFLFL+TLFIQRGRHETTWT+LRRFGY D L+LT +YL PL+ +PP C+TE
Sbjct: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
Query: 301 LNHLGYQFVQRVFEKHDQDRDGALSPVELQSLFSVFPAAPWGPELPRTVRT-EAGRLPLH 359
LNH Y F+Q F+KHD DRD ALSP EL+ LF VFP PWGP++ TV T E G +
Sbjct: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
Query: 360 GYLCQWTLVTYLDVRSCLGHLGYLGYPTLCEQD-QAHAITVTREKRLDQEKGQTQRSVLL 418
G+L QWTL TYLDV+ CL +LGYLGY L EQ+ QA A+TVTR+K++D +K QTQR+V
Sbjct: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
Query: 419 CKVVGARGVGKSAFLQAFLGRGLGHQD--TREQPPGYAIDTVQVNGQEKYLILCEVGTDG 476
C V+G + GKS LQA LGR L Q + YAI+TV V GQEKYL+L ++
Sbjct: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
Query: 477 LLATSLDATCDVACLMFDGSDPKSFAHCASVYKHHYMDGQTPCLFVSSKADLPEGVAVSG 536
L T + CDV CL++D S+PKSF +CA ++K H+MD + PCL V++K+DL E
Sbjct: 481 FL-TEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYS 539
Query: 537 PSPAEFCRKHRLPAPVPFSCAGPAEPSTTIFTQLATMAAFP------------------- 577
SP +FCRKH++P P F+C PS IF +L TMA +P
Sbjct: 540 ISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHARLRCMCTCNRCTFCICQ 599
Query: 578 ----------------------HLVHAELHPSSFWLRGLLGVVGAAVAAVLSFSLYRVLV 615
H+ A+L S+FWLR GA V AVL F++Y+ L+
Sbjct: 600 NFLNSDLLQSVKNKIFTAVLNRHVTQADLKSSTFWLRASF---GATVFAVLGFAMYKALL 656
Query: 616 KSQ 618
K +
Sbjct: 657 KQR 659
>gi|75750480 ras homolog gene family, member T1 isoform 1 [Homo
sapiens]
Length = 691
Score = 716 bits (1849), Expect = 0.0
Identities = 354/581 (60%), Positives = 442/581 (76%), Gaps = 5/581 (0%)
Query: 1 MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSE 60
M++DVRILL+GE +VGKTSLI+SLV EEFPEEVPPRAEEITIPADVTPE+VPTHIVDYSE
Sbjct: 1 MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
Query: 61 AEQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKS 120
AEQ+DE+L +EI +ANV+C+VY V+ + +I+K+ ++WIPL+N T + R+P+ILVGNKS
Sbjct: 61 AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
Query: 121 DLRSGSSMEAVLPIMSQFPEIETCVECSAKNLRNISELFYYAQKAVLHPTAPLYDPEAKQ 180
DL SSME +LPIM+Q+ EIETCVECSAKNL+NISELFYYAQKAVLHPT PLY PE K+
Sbjct: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
Query: 181 LRPACAQALTRIFRLSDQDLDQALSDEELNAFQKSCFGHPLAPQALEDVKTVVCRNVAGG 240
++PAC +ALTRIF++SDQD D L+D ELN FQ+ CF PLAPQALEDVK VV ++++ G
Sbjct: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
Query: 241 VREDRLTLDGFLFLNTLFIQRGRHETTWTILRRFGYSDALELTADYLSPLIHVPPGCSTE 300
V + LTL GFLFL+TLFIQRGRHETTWT+LRRFGY D L+LT +YL PL+ +PP C+TE
Sbjct: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
Query: 301 LNHLGYQFVQRVFEKHDQDRDGALSPVELQSLFSVFPAAPWGPELPRTVRT-EAGRLPLH 359
LNH Y F+Q F+KHD DRD ALSP EL+ LF VFP PWGP++ TV T E G +
Sbjct: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
Query: 360 GYLCQWTLVTYLDVRSCLGHLGYLGYPTLCEQD-QAHAITVTREKRLDQEKGQTQRSVLL 418
G+L QWTL TYLDV+ CL +LGYLGY L EQ+ QA A+TVTR+K++D +K QTQR+V
Sbjct: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
Query: 419 CKVVGARGVGKSAFLQAFLGRGLGHQD--TREQPPGYAIDTVQVNGQEKYLILCEVGTDG 476
C V+G + GKS LQA LGR L Q + YAI+TV V GQEKYL+L ++
Sbjct: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
Query: 477 LLATSLDATCDVACLMFDGSDPKSFAHCASVYKHHYMDGQTPCLFVSSKADLPEGVAVSG 536
L T + CDV CL++D S+PKSF +CA ++K H+MD + PCL V++K+DL E
Sbjct: 481 FL-TEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYS 539
Query: 537 PSPAEFCRKHRLPAPVPFSCAGPAEPSTTIFTQLATMAAFP 577
SP +FCRKH++P P F+C PS IF +L TMA +P
Sbjct: 540 ISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP 580
Score = 37.4 bits (85), Expect = 0.041
Identities = 18/41 (43%), Positives = 26/41 (63%), Gaps = 3/41 (7%)
Query: 578 HLVHAELHPSSFWLRGLLGVVGAAVAAVLSFSLYRVLVKSQ 618
H+ A+L S+FWLR GA V AVL F++Y+ L+K +
Sbjct: 654 HVTQADLKSSTFWLRASF---GATVFAVLGFAMYKALLKQR 691
>gi|4757764 ras homolog gene family, member B [Homo sapiens]
Length = 196
Score = 70.5 bits (171), Expect = 4e-12
Identities = 52/176 (29%), Positives = 79/176 (44%), Gaps = 17/176 (9%)
Query: 6 RILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSEAEQT 64
+++++G+ GKT L++ +EFPE VP E +V ++V + D + E
Sbjct: 7 KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
Query: 65 DEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDLRS 124
D +V+ + + V ++E I KW+P V P VPIILV NK DLRS
Sbjct: 67 DRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFC---PNVPIILVANKKDLRS 123
Query: 125 GSSMEAVLPIMSQFP-------------EIETCVECSAKNLRNISELFYYAQKAVL 167
+ L M Q P + +ECSAK + E+F A +A L
Sbjct: 124 DEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAAL 179
>gi|38016957 ras homolog gene family, member F [Homo sapiens]
Length = 211
Score = 67.4 bits (163), Expect = 4e-11
Identities = 48/180 (26%), Positives = 82/180 (45%), Gaps = 17/180 (9%)
Query: 2 RRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRA-EEITIPADVTPEKVPTHIVDYSE 60
R++++I+++G+ GKTSL++ FPE P E+ T V ++V ++ D +
Sbjct: 17 RKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAG 76
Query: 61 AEQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKS 120
E D ++V + YDV + + + KW P V T +P++L+G K+
Sbjct: 77 QEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEV---THFCRGIPMVLIGCKT 133
Query: 121 DLRSGSSM-----EAVLPIMSQFPEIETC--------VECSAKNLRNISELFYYAQKAVL 167
DLR A L ++ + C +ECSAK N+ ++F A K L
Sbjct: 134 DLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVAL 193
>gi|46249393 ras homolog gene family, member G [Homo sapiens]
Length = 191
Score = 66.2 bits (160), Expect = 8e-11
Identities = 49/182 (26%), Positives = 81/182 (44%), Gaps = 17/182 (9%)
Query: 3 RDVRILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSEA 61
+ ++ +++G+ VGKT L++ FP+E +P + + + V V ++ D +
Sbjct: 2 QSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQ 61
Query: 62 EQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSD 121
E+ D + NV + + ++ + E +R KW P V P VPI+LVG K D
Sbjct: 62 EEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEV---CHHCPDVPILLVGTKKD 118
Query: 122 LRSGSSMEAVLPIMSQFP-------------EIETCVECSAKNLRNISELFYYAQKAVLH 168
LR+ L Q P +ECSA + E+F A +AVL+
Sbjct: 119 LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLN 178
Query: 169 PT 170
PT
Sbjct: 179 PT 180
>gi|10835049 ras homolog gene family, member A [Homo sapiens]
Length = 193
Score = 65.5 bits (158), Expect = 1e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 17/176 (9%)
Query: 6 RILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSEAEQT 64
+++++G+ GKT L++ ++FPE VP E +V ++V + D + E
Sbjct: 7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
Query: 65 DEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDLRS 124
D +V+ + + + ++E I KW P V P VPIILVGNK DLR+
Sbjct: 67 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC---PNVPIILVGNKKDLRN 123
Query: 125 GSSMEAVLPIMSQFPEIET-------------CVECSAKNLRNISELFYYAQKAVL 167
L M Q P +ECSAK + E+F A +A L
Sbjct: 124 DEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL 179
>gi|111494251 ras homolog gene family, member C precursor [Homo
sapiens]
Length = 193
Score = 64.7 bits (156), Expect = 2e-10
Identities = 50/176 (28%), Positives = 76/176 (43%), Gaps = 17/176 (9%)
Query: 6 RILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSEAEQT 64
+++++G+ GKT L++ ++FPE VP E +V ++V + D + E
Sbjct: 7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66
Query: 65 DEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDLRS 124
D +V+ + + + ++E I KW P V P VPIILVGNK DLR
Sbjct: 67 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC---PNVPIILVGNKKDLRQ 123
Query: 125 GSSMEAVLPIMSQFP-------------EIETCVECSAKNLRNISELFYYAQKAVL 167
L M Q P +ECSAK + E+F A +A L
Sbjct: 124 DEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL 179
>gi|111494248 ras homolog gene family, member C precursor [Homo
sapiens]
Length = 193
Score = 64.7 bits (156), Expect = 2e-10
Identities = 50/176 (28%), Positives = 76/176 (43%), Gaps = 17/176 (9%)
Query: 6 RILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSEAEQT 64
+++++G+ GKT L++ ++FPE VP E +V ++V + D + E
Sbjct: 7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66
Query: 65 DEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDLRS 124
D +V+ + + + ++E I KW P V P VPIILVGNK DLR
Sbjct: 67 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC---PNVPIILVGNKKDLRQ 123
Query: 125 GSSMEAVLPIMSQFP-------------EIETCVECSAKNLRNISELFYYAQKAVL 167
L M Q P +ECSAK + E+F A +A L
Sbjct: 124 DEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL 179
>gi|28395033 ras homolog gene family, member C precursor [Homo
sapiens]
Length = 193
Score = 64.7 bits (156), Expect = 2e-10
Identities = 50/176 (28%), Positives = 76/176 (43%), Gaps = 17/176 (9%)
Query: 6 RILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSEAEQT 64
+++++G+ GKT L++ ++FPE VP E +V ++V + D + E
Sbjct: 7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66
Query: 65 DEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDLRS 124
D +V+ + + + ++E I KW P V P VPIILVGNK DLR
Sbjct: 67 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC---PNVPIILVGNKKDLRQ 123
Query: 125 GSSMEAVLPIMSQFP-------------EIETCVECSAKNLRNISELFYYAQKAVL 167
L M Q P +ECSAK + E+F A +A L
Sbjct: 124 DEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL 179
>gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]
Length = 191
Score = 64.3 bits (155), Expect = 3e-10
Identities = 51/195 (26%), Positives = 81/195 (41%), Gaps = 23/195 (11%)
Query: 5 VRILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSEAEQ 63
++ +++G+ VGKT L++S +FP E VP + + + E + D + E
Sbjct: 4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63
Query: 64 TDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDLR 123
D + +V V + V ++ E ++ KW+P + T P+ P +LVG + DLR
Sbjct: 64 YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEI---THHCPKTPFLLVGTQIDLR 120
Query: 124 SGSSMEAVLPIMSQFP-------------EIETCVECSAKNLRNISELFYYAQKAVLHPT 170
S L Q P + VECSA R + +F A A L P
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALEP- 179
Query: 171 APLYDPEAKQLRPAC 185
PE + R C
Sbjct: 180 -----PETQPKRKCC 189
>gi|50263042 ras-like protein TC10 [Homo sapiens]
Length = 205
Score = 63.2 bits (152), Expect = 7e-10
Identities = 47/179 (26%), Positives = 80/179 (44%), Gaps = 17/179 (9%)
Query: 5 VRILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSEAEQ 63
++ +++G+ VGKT L++S + FPEE VP + + V ++ + D + E
Sbjct: 10 LKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQED 69
Query: 64 TDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDLR 123
D +V + + V A+ + ++ +W+P + P VP +L+G + DLR
Sbjct: 70 YDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELK---EYAPNVPFLLIGTQIDLR 126
Query: 124 SGSSMEAVLPIMSQFP-----------EIETC--VECSAKNLRNISELFYYAQKAVLHP 169
A L M + P EI C VECSA + + +F A A+L P
Sbjct: 127 DDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTP 185
>gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]
Length = 191
Score = 62.8 bits (151), Expect = 9e-10
Identities = 47/182 (25%), Positives = 77/182 (42%), Gaps = 17/182 (9%)
Query: 5 VRILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSEAEQ 63
++ +++G+ VGKT L++S +FP E VP + + + E + D + E
Sbjct: 4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63
Query: 64 TDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDLR 123
D + +V V + V ++ E ++ KW+P + T P+ P +LVG + DLR
Sbjct: 64 YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEI---THHCPKTPFLLVGTQIDLR 120
Query: 124 SGSSMEAVLPIMSQFP-------------EIETCVECSAKNLRNISELFYYAQKAVLHPT 170
S L Q P + VECSA + + +F A A L P
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP 180
Query: 171 AP 172
P
Sbjct: 181 EP 182
>gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]
Length = 191
Score = 62.8 bits (151), Expect = 9e-10
Identities = 47/182 (25%), Positives = 77/182 (42%), Gaps = 17/182 (9%)
Query: 5 VRILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSEAEQ 63
++ +++G+ VGKT L++S +FP E VP + + + E + D + E
Sbjct: 4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63
Query: 64 TDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDLR 123
D + +V V + V ++ E ++ KW+P + T P+ P +LVG + DLR
Sbjct: 64 YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEI---THHCPKTPFLLVGTQIDLR 120
Query: 124 SGSSMEAVLPIMSQFP-------------EIETCVECSAKNLRNISELFYYAQKAVLHPT 170
S L Q P + VECSA + + +F A A L P
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP 180
Query: 171 AP 172
P
Sbjct: 181 EP 182
>gi|7656900 ras homolog D [Homo sapiens]
Length = 210
Score = 62.8 bits (151), Expect = 9e-10
Identities = 50/179 (27%), Positives = 82/179 (45%), Gaps = 17/179 (9%)
Query: 3 RDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRA-EEITIPADVTPEKVPTHIVDYSEA 61
R V+++L+G+ GKTSL++ FPE P E + V + V HI D +
Sbjct: 16 RSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKPVHLHIWDTAGQ 75
Query: 62 EQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSD 121
+ D A+V+ + +DV+ + + I +W P VN +VPII+VG K+D
Sbjct: 76 DDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFC---KKVPIIVVGCKTD 132
Query: 122 LRSGSSM------EAVLPI-------MSQFPEIETCVECSAKNLRNISELFYYAQKAVL 167
LR S+ + P+ M++ +ECSA+ N+ +F A + L
Sbjct: 133 LRKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHDNVHAVFQEAAEVAL 191
>gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
sapiens]
Length = 192
Score = 62.0 bits (149), Expect = 2e-09
Identities = 53/180 (29%), Positives = 85/180 (47%), Gaps = 19/180 (10%)
Query: 5 VRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSEAEQT 64
++ +++G+ VGKT L++S FP E P + A+V + P ++ + A Q
Sbjct: 4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFD-NYSANVMVDSKPVNLGLWDTAGQE 62
Query: 65 D-EELRE-EIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDL 122
D + LR + +V + + + A+ E +R KW P V P PIILVG K DL
Sbjct: 63 DYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVR---HHCPSTPIILVGTKLDL 119
Query: 123 RSGSSM------EAVLPI-----MSQFPEIETC--VECSAKNLRNISELFYYAQKAVLHP 169
R + + PI ++ EI++ +ECSA R + +F A +AVL P
Sbjct: 120 RDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCP 179
>gi|11034843 ras homolog gene family, member U [Homo sapiens]
Length = 258
Score = 62.0 bits (149), Expect = 2e-09
Identities = 41/171 (23%), Positives = 78/171 (45%), Gaps = 17/171 (9%)
Query: 3 RDVRILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSEA 61
R V+ +L+G+ VGKTSL++S +P E +P + + V V + D +
Sbjct: 48 RGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQ 107
Query: 62 EQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSD 121
++ D+ ++ + + V ++ + + KW+P + P+ PIILVG +SD
Sbjct: 108 DEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIR---CHCPKAPIILVGTQSD 164
Query: 122 LRSGSSM-------------EAVLPIMSQFPEIETCVECSAKNLRNISELF 159
LR + E + ++ + + +ECSA +N+ E+F
Sbjct: 165 LREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVF 215
>gi|229577148 ras homolog gene family, member V [Homo sapiens]
Length = 236
Score = 61.2 bits (147), Expect = 3e-09
Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 20/171 (11%)
Query: 5 VRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSEAEQT 64
++ +L+G+ VGK+SLI+S +P P A + T V + P I + A Q
Sbjct: 32 IKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALD-TFSVQVLVDGAPVRIELWDTAGQE 90
Query: 65 D-EELREEIH-KANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDL 122
D + LR + +V + V + ++ + I KW+P + T P+ P++LVG ++DL
Sbjct: 91 DFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIR---THNPQAPVLLVGTQADL 147
Query: 123 RSGSSM---------EAVLP---IMSQFPEIETC--VECSAKNLRNISELF 159
R ++ E +P +I C +ECSA +N+ E+F
Sbjct: 148 RDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVF 198
>gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1
[Homo sapiens]
Length = 192
Score = 60.8 bits (146), Expect = 3e-09
Identities = 56/196 (28%), Positives = 88/196 (44%), Gaps = 25/196 (12%)
Query: 5 VRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSEAEQT 64
++ +++G+ VGKT L++S FP E P + A+V + P ++ + A Q
Sbjct: 4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFD-NYSANVMVDGKPVNLGLWDTAGQE 62
Query: 65 D-EELRE-EIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDL 122
D + LR + +V + + + A+ E +R KW P V P PIILVG K DL
Sbjct: 63 DYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVR---HHCPNTPIILVGTKLDL 119
Query: 123 RSGSSM------EAVLPI-----MSQFPEIETC--VECSAKNLRNISELFYYAQKAVLHP 169
R + + PI ++ EI +ECSA R + +F A +AVL P
Sbjct: 120 RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCP 179
Query: 170 TAPLYDPEAKQLRPAC 185
P K+ + C
Sbjct: 180 ------PPVKKRKRKC 189
>gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens]
Length = 229
Score = 60.5 bits (145), Expect = 5e-09
Identities = 51/190 (26%), Positives = 82/190 (43%), Gaps = 6/190 (3%)
Query: 3 RDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPA-DVTPEKVPTHIVDYSEA 61
RD R++++G A VGK++L+ F E P E + + HI D
Sbjct: 36 RDYRVVVVGTAGVGKSTLLHKWASGNFRHEYLPTIENTYCQLLGCSHGVLSLHITDSKSG 95
Query: 62 EQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSD 121
+ R I + + +VY V+++ T+E+++ + + + PI+LVGNKSD
Sbjct: 96 DGNRALQRHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKGNNLHKFPIVLVGNKSD 155
Query: 122 LRSGSSMEAVLPIMSQFPEIETC--VECSAKNLRNISELFYYAQKAVLHPTAPLYDPEAK 179
+ E L + C +E SAK N+ ELF+ PT L +PE K
Sbjct: 156 ---DTHREVALNDGATCAMEWNCAFMEISAKTDVNVQELFHMLLNYKKKPTTGLQEPEKK 212
Query: 180 QLRPACAQAL 189
P + L
Sbjct: 213 SQMPNTTEKL 222
>gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family,
small GTP binding protein Rac3) [Homo sapiens]
Length = 192
Score = 60.1 bits (144), Expect = 6e-09
Identities = 55/190 (28%), Positives = 88/190 (46%), Gaps = 20/190 (10%)
Query: 5 VRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSEAEQT 64
++ +++G+ VGKT L++S FP E P + A+V + P ++ + A Q
Sbjct: 4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFD-NYSANVMVDGKPVNLGLWDTAGQE 62
Query: 65 D-EELRE-EIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDL 122
D + LR + +V + + + A+ E +R KW P V P PI+LVG K DL
Sbjct: 63 DYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVR---HHCPHTPILLVGTKLDL 119
Query: 123 RSGSSM------EAVLPI-----MSQFPEIETC--VECSAKNLRNISELFYYAQKAVLHP 169
R + + PI ++ EI + +ECSA R + +F A +AVL P
Sbjct: 120 RDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCP 179
Query: 170 TAPLYDPEAK 179
P+ P K
Sbjct: 180 -PPVKKPGKK 188
>gi|4758996 Ras-related protein Rab-33A [Homo sapiens]
Length = 237
Score = 58.2 bits (139), Expect = 2e-08
Identities = 53/196 (27%), Positives = 90/196 (45%), Gaps = 24/196 (12%)
Query: 3 RDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPAD-------VTPEKVPTHI 55
R +I+++G++ VGKT L G FP++ E TI D + EK+ +
Sbjct: 35 RIFKIIVIGDSNVGKTCLTFRFCGGTFPDKT-----EATIGVDFREKTVEIEGEKIKVQV 89
Query: 56 VDYSEAEQTDEELREEIHK-ANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPII 114
D + E+ + + E ++ + V VYDV++ + ++ WI NG P VP +
Sbjct: 90 WDTAGQERFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNLK-MWIQECNGHAVP-PLVPKV 147
Query: 115 LVGNKSDLRSGSSMEAVLPIMSQFPEIETCVECSAKN---LRNISELF------YYAQKA 165
LVGNK DLR + + L + E SAK+ +N+ +F AQK+
Sbjct: 148 LVGNKCDLREQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKS 207
Query: 166 VLHPTAPLYDPEAKQL 181
+L+ A + ++L
Sbjct: 208 LLYRDAERQQGKVQKL 223
>gi|40255119 RAS and EF-hand domain containing [Homo sapiens]
Length = 740
Score = 57.4 bits (137), Expect = 4e-08
Identities = 49/174 (28%), Positives = 81/174 (46%), Gaps = 21/174 (12%)
Query: 6 RILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPAD-------VTPEKVPTHIVDY 58
+I+L G+A VGK+S ++ L EF E + T+ D V E+ + D
Sbjct: 543 KIVLAGDAAVGKSSFLMRLCKNEFRENI-----SATLGVDFQMKTLIVDGERTVLQLWDT 597
Query: 59 SEAEQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGN 118
+ E+ + KA+ V ++YDV+ E + IR +W+ ++ + VPI+LVGN
Sbjct: 598 AGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIR-EWVDMIEDAAHE--TVPIMLVGN 654
Query: 119 KSDLRSGSSMEAVLPIMSQFPEIETCV------ECSAKNLRNISELFYYAQKAV 166
K+D+R ++ E + F E E SAK+ NI E + + V
Sbjct: 655 KADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREV 708
>gi|4885069 ras homolog gene family, member E [Homo sapiens]
Length = 244
Score = 57.0 bits (136), Expect = 5e-08
Identities = 48/182 (26%), Positives = 82/182 (45%), Gaps = 22/182 (12%)
Query: 6 RILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSEAEQT 64
+I+++G++Q GKT+L+ + FPE VP E T ++ +++ + D S +
Sbjct: 25 KIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYY 84
Query: 65 DEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQG--PRVPIILVGNKSDL 122
D ++ V + +D+S T++ + KW G Q P ++LVG KSDL
Sbjct: 85 DNVRPLSYPDSDAVLICFDISRPETLDSVLKKW-----KGEIQEFCPNTKMLLVGCKSDL 139
Query: 123 RSGSSMEAVLPIMSQFP-------------EIETCVECSAKNLRN-ISELFYYAQKAVLH 168
R+ S L Q P T +ECSA N + ++F+ A A ++
Sbjct: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVN 199
Query: 169 PT 170
T
Sbjct: 200 KT 201
>gi|16903164 ras homolog gene family, member J [Homo sapiens]
Length = 214
Score = 56.2 bits (134), Expect = 9e-08
Identities = 41/182 (22%), Positives = 79/182 (43%), Gaps = 17/182 (9%)
Query: 2 RRDVRILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSE 60
++ ++ +++G+ VGKT L++S + FPEE VP + + V ++ + D +
Sbjct: 19 KKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAG 78
Query: 61 AEQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKS 120
E ++ +V + + V A+ ++ +W+P + P VP +L+G +
Sbjct: 79 QEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCM---PHVPYVLIGTQI 135
Query: 121 DLRSGSSMEAVLPIMSQFP-------------EIETCVECSAKNLRNISELFYYAQKAVL 167
DLR A L M + P + +ECSA + + +F A +
Sbjct: 136 DLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIF 195
Query: 168 HP 169
HP
Sbjct: 196 HP 197
>gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens]
Length = 298
Score = 54.7 bits (130), Expect = 2e-07
Identities = 50/161 (31%), Positives = 75/161 (46%), Gaps = 13/161 (8%)
Query: 6 RILLLGEAQVGKTSLILSLVGEE---FPEEVPPRAEEITIPADVTPEKVPTHIVDYSEAE 62
R++LLG+ VGKTSL G++ E++ E T+ D E +VD EAE
Sbjct: 82 RVVLLGDPGVGKTSLASLFAGKQERDLHEQLGEDVYERTLTVD--GEDTTLVVVDTWEAE 139
Query: 63 QTDEELREE--IHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKS 120
+ D+ +E + + +VY +++ + E I L T Q VPIILVGNK+
Sbjct: 140 KLDKSWSQESCLQGGSAYVIVYSIADRGSFESASELRIQLRR--THQADHVPIILVGNKA 197
Query: 121 DLRSGSSMEAVLPIMSQFPEIETC--VECSAKNLRNISELF 159
DL E + + C +E SA N++ELF
Sbjct: 198 DL--ARCREVSVEEGRACAVVFDCKFIETSATLQHNVAELF 236
>gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Rac1b
[Homo sapiens]
Length = 211
Score = 54.3 bits (129), Expect = 3e-07
Identities = 57/215 (26%), Positives = 90/215 (41%), Gaps = 44/215 (20%)
Query: 5 VRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSEAEQT 64
++ +++G+ VGKT L++S FP E P + A+V + P ++ + A Q
Sbjct: 4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFD-NYSANVMVDGKPVNLGLWDTAGQE 62
Query: 65 D-EELR--------------------EEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNG 103
D + LR ++ A+V + + + A+ E +R KW P V
Sbjct: 63 DYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVR- 121
Query: 104 GTTQGPRVPIILVGNKSDLRSGSSM------EAVLPI-----MSQFPEIETC--VECSAK 150
P PIILVG K DLR + + PI ++ EI +ECSA
Sbjct: 122 --HHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSAL 179
Query: 151 NLRNISELFYYAQKAVLHPTAPLYDPEAKQLRPAC 185
R + +F A +AVL P P K+ + C
Sbjct: 180 TQRGLKTVFDEAIRAVLCP------PPVKKRKRKC 208
>gi|4885581 Rho family GTPase 2 [Homo sapiens]
Length = 227
Score = 52.8 bits (125), Expect = 9e-07
Identities = 42/179 (23%), Positives = 86/179 (48%), Gaps = 22/179 (12%)
Query: 6 RILLLGEAQVGKTSLILSLVGEEFPEE-VPPRAEEITIPADVTPEKVPTHIVDYSEAEQT 64
+I+++G+A+ GKT+L+ + +P VP E T ++ ++ ++ D S +
Sbjct: 9 KIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYY 68
Query: 65 DEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQG--PRVPIILVGNKSDL 122
D ++ V + +D+S T++ + KW G TQ P ++LVG K D+
Sbjct: 69 DNVRPLAYPDSDAVLICFDISRPETLDSVLKKW-----QGETQEFCPNAKVVLVGCKLDM 123
Query: 123 RSG------SSMEAVLPIMSQFPEI-------ETCVECSAKNL-RNISELFYYAQKAVL 167
R+ S + ++P+ + + + VECS+++ R++ ++F+ A A L
Sbjct: 124 RTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASL 182
>gi|4757770 ras homolog gene family, member H [Homo sapiens]
Length = 191
Score = 51.6 bits (122), Expect = 2e-06
Identities = 43/176 (24%), Positives = 81/176 (46%), Gaps = 12/176 (6%)
Query: 1 MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSE 60
M ++ +L+G++ VGKTSL++ E FPE P E T DV + + + +
Sbjct: 1 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENT-GVDVFMDGIQISLGLWDT 59
Query: 61 A-EQTDEELRE-EIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGN 118
A +R +A+VV + Y V+ + ++ KWI + P P+++V
Sbjct: 60 AGNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNL---PCTPVLVVAT 116
Query: 119 KSDLRS-GSSMEAVLPIM-----SQFPEIETCVECSAKNLRNISELFYYAQKAVLH 168
++D R G + + M +Q + +ECSA + R + ++F A + ++
Sbjct: 117 QTDQREMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVN 172
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,452,685
Number of Sequences: 37866
Number of extensions: 1223975
Number of successful extensions: 3776
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 144
Number of HSP's that attempted gapping in prelim test: 3530
Number of HSP's gapped (non-prelim): 235
length of query: 618
length of database: 18,247,518
effective HSP length: 108
effective length of query: 510
effective length of database: 14,157,990
effective search space: 7220574900
effective search space used: 7220574900
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.