Search of human proteins with 20149594

Search of human proteins with 20149594

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
         (724 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]          1430   0.0  
gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s...  1263   0.0  
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s...  1263   0.0  
gi|4507677 heat shock protein 90kDa beta, member 1 [Homo sapiens]     657   0.0  
gi|155722983 TNF receptor-associated protein 1 [Homo sapiens]         196   6e-50
gi|34878777 ring finger protein 20 [Homo sapiens]                      55   2e-07
gi|221219020 NYD-SP11 protein [Homo sapiens]                           50   1e-05
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]            49   1e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    49   2e-05
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]       49   2e-05
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ...    49   2e-05
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    48   3e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    48   3e-05
gi|148746183 ubiquitin specific protease 35 [Homo sapiens]             48   3e-05
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    47   6e-05
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    47   6e-05
gi|38569484 kinesin family member 21A [Homo sapiens]                   47   6e-05
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          47   8e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    46   1e-04
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]     46   1e-04
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is...    46   1e-04
gi|17975763 myelin transcription factor 1 [Homo sapiens]               45   2e-04
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]       45   2e-04
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]       45   2e-04
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]        45   2e-04
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    45   2e-04
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    45   2e-04
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    45   2e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     45   2e-04
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...    45   3e-04

>gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
          Length = 724

 Score = 1430 bits (3702), Expect = 0.0
 Identities = 724/724 (100%), Positives = 724/724 (100%)

Query: 1   MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT 60
           MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT
Sbjct: 1   MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT 60

Query: 61  DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG 120
           DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG
Sbjct: 61  DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG 120

Query: 121 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK 180
           ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK
Sbjct: 121 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK 180

Query: 181 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE 240
           VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE
Sbjct: 181 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE 240

Query: 241 DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE 300
           DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE
Sbjct: 241 DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE 300

Query: 301 YGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRV 360
           YGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRV
Sbjct: 301 YGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRV 360

Query: 361 FIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA 420
           FIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA
Sbjct: 361 FIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA 420

Query: 421 EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQ 480
           EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQ
Sbjct: 421 EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQ 480

Query: 481 KSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEG 540
           KSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEG
Sbjct: 481 KSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEG 540

Query: 541 LELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTA 600
           LELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTA
Sbjct: 541 LELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTA 600

Query: 601 NMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFE 660
           NMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFE
Sbjct: 601 NMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFE 660

Query: 661 TALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRM 720
           TALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRM
Sbjct: 661 TALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRM 720

Query: 721 EEVD 724
           EEVD
Sbjct: 721 EEVD 724


>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
           sapiens]
          Length = 732

 Score = 1263 bits (3268), Expect = 0.0
 Identities = 628/732 (85%), Positives = 684/732 (93%), Gaps = 8/732 (1%)

Query: 1   MPEEVHHG-----EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIR 55
           MPEE         EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIR
Sbjct: 1   MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR 60

Query: 56  YESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFME 115
           YESLTDPSKLDSGKEL I++IPN Q+RTLT+VDTGIGMTKADLINNLGTIAKSGTKAFME
Sbjct: 61  YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120

Query: 116 ALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPI 175
           ALQAGADISMIGQFGVGFYSAYLVAEKV VITKHNDDEQYAWESSAGGSFTVR D GEP+
Sbjct: 121 ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM 180

Query: 176 GRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKG 235
           GRGTKVILHLKEDQTEYLEERR+KE+VKKHSQFIGYPITL++EKER+KE+SDDEAEE++ 
Sbjct: 181 GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED 240

Query: 236 ---EKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRN 292
              EKE+E+K+ E+KP+IEDVGSDEE++     KKK KKIKEKYIDQEELNKTKPIWTRN
Sbjct: 241 KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN 300

Query: 293 PDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNN 352
           PDDIT EEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF+PRRAPFDLFEN+KKKNN
Sbjct: 301 PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN 360

Query: 353 IKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKC 412
           IKLYVRRVFIMD+C+ELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKN+VKKC
Sbjct: 361 IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC 420

Query: 413 LELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEY 472
           LELF+ELAEDKENYKKFYE FSKN+KLGIHEDS NR++LSELLRY+TS SGDEM SL +Y
Sbjct: 421 LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY 480

Query: 473 VSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKS 532
            +RMKE QK IYYITGE+K+QVANSAFVER+RK G EV+YM EPIDEYCVQQLKEF+GK+
Sbjct: 481 CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT 540

Query: 533 LVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIV 592
           LVSVTKEGLELPEDEEEKKK EE K KFENLCK+MK+IL+KKVEKV +SNRLV+SPCCIV
Sbjct: 541 LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV 600

Query: 593 TSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVK 652
           TSTYGWTANMERIMKAQALRDNSTMGYM AKKHLEINPDH I+ETLRQKAEADKNDK+VK
Sbjct: 601 TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK 660

Query: 653 DLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLE 712
           DLV+LL+ETALLSSGFSLEDPQTH+NRIYRMIKLGLGIDED+  A++ +AAV +E+PPLE
Sbjct: 661 DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE 720

Query: 713 GDEDASRMEEVD 724
           GD+D SRMEEVD
Sbjct: 721 GDDDTSRMEEVD 732


>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
           sapiens]
          Length = 854

 Score = 1263 bits (3268), Expect = 0.0
 Identities = 628/732 (85%), Positives = 684/732 (93%), Gaps = 8/732 (1%)

Query: 1   MPEEVHHG-----EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIR 55
           MPEE         EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIR
Sbjct: 123 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR 182

Query: 56  YESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFME 115
           YESLTDPSKLDSGKEL I++IPN Q+RTLT+VDTGIGMTKADLINNLGTIAKSGTKAFME
Sbjct: 183 YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 242

Query: 116 ALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPI 175
           ALQAGADISMIGQFGVGFYSAYLVAEKV VITKHNDDEQYAWESSAGGSFTVR D GEP+
Sbjct: 243 ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM 302

Query: 176 GRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKG 235
           GRGTKVILHLKEDQTEYLEERR+KE+VKKHSQFIGYPITL++EKER+KE+SDDEAEE++ 
Sbjct: 303 GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED 362

Query: 236 ---EKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRN 292
              EKE+E+K+ E+KP+IEDVGSDEE++     KKK KKIKEKYIDQEELNKTKPIWTRN
Sbjct: 363 KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN 422

Query: 293 PDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNN 352
           PDDIT EEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF+PRRAPFDLFEN+KKKNN
Sbjct: 423 PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN 482

Query: 353 IKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKC 412
           IKLYVRRVFIMD+C+ELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKN+VKKC
Sbjct: 483 IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC 542

Query: 413 LELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEY 472
           LELF+ELAEDKENYKKFYE FSKN+KLGIHEDS NR++LSELLRY+TS SGDEM SL +Y
Sbjct: 543 LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY 602

Query: 473 VSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKS 532
            +RMKE QK IYYITGE+K+QVANSAFVER+RK G EV+YM EPIDEYCVQQLKEF+GK+
Sbjct: 603 CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT 662

Query: 533 LVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIV 592
           LVSVTKEGLELPEDEEEKKK EE K KFENLCK+MK+IL+KKVEKV +SNRLV+SPCCIV
Sbjct: 663 LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV 722

Query: 593 TSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVK 652
           TSTYGWTANMERIMKAQALRDNSTMGYM AKKHLEINPDH I+ETLRQKAEADKNDK+VK
Sbjct: 723 TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK 782

Query: 653 DLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLE 712
           DLV+LL+ETALLSSGFSLEDPQTH+NRIYRMIKLGLGIDED+  A++ +AAV +E+PPLE
Sbjct: 783 DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE 842

Query: 713 GDEDASRMEEVD 724
           GD+D SRMEEVD
Sbjct: 843 GDDDTSRMEEVD 854


>gi|4507677 heat shock protein 90kDa beta, member 1 [Homo sapiens]
          Length = 803

 Score =  657 bits (1696), Expect = 0.0
 Identities = 353/737 (47%), Positives = 495/737 (67%), Gaps = 34/737 (4%)

Query: 4   EVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPS 63
           ++    E+ E FAFQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR  SLTD +
Sbjct: 65  QIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDEN 124

Query: 64  KLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQA 119
            L   +EL + I  + ++  L + DTG+GMT+ +L+ NLGTIAKSGT  F+    EA + 
Sbjct: 125 ALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQED 184

Query: 120 GADIS-MIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGR 177
           G   S +IGQFGVGFYSA+LVA+KV+V +KHN+D Q+ WES +   F+V AD  G  +GR
Sbjct: 185 GQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSN-EFSVIADPRGNTLGR 243

Query: 178 GTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEK 237
           GT + L LKE+ ++YLE   +K +VKK+SQFI +PI ++  K    E  ++  EEE+  K
Sbjct: 244 GTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKT---ETVEEPMEEEEAAK 300

Query: 238 EEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDIT 297
           EE+++ D+E         +EE++   +KK KTKK+++   D E +N  KPIW R   ++ 
Sbjct: 301 EEKEESDDE------AAVEEEEE---EKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVE 351

Query: 298 QEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFEN--KKKKNNIKL 355
           ++EY  FYKS + + +D +A  HF+ EG++ F+++LF+P  AP  LF+    KK + IKL
Sbjct: 352 EDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKL 411

Query: 356 YVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLEL 415
           YVRRVFI D   +++P+YLNF++GVVDS+DLPLN+SRE LQQ K+LKVIRK +V+K L++
Sbjct: 412 YVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDM 471

Query: 416 FSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSR 475
             ++A+DK N   F++ F  N+KLG+ ED +NR RL++LLR+ +S    ++TSL +YV R
Sbjct: 472 IKKIADDKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVER 530

Query: 476 MKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVS 535
           MKE Q  IY++ G S+++  +S FVER+ K+G+EV+Y+TEP+DEYC+Q L EFDGK   +
Sbjct: 531 MKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQN 590

Query: 536 VTKEGLELPEDEEEKKKMEESKAKFENLCKLMKE-ILDKKVEKVTISNRLVSSPCCIVTS 594
           V KEG++  E E+ K+  E  + +FE L   MK+  L  K+EK  +S RL  SPC +V S
Sbjct: 591 VAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVAS 650

Query: 595 TYGWTANMERIMKAQAL---RDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAV 651
            YGW+ NMERIMKAQA    +D ST  Y   KK  EINP HP++  + ++ + D++DK V
Sbjct: 651 QYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTV 710

Query: 652 KDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDED----EVAAEEPNAAVPDE 707
            DL V+LFETA L SG+ L D + + +RI RM++L L ID D    E   EEP     D 
Sbjct: 711 LDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDT 770

Query: 708 IPPLEGDEDASRMEEVD 724
               E DED    EE+D
Sbjct: 771 TEDTEQDED----EEMD 783



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 4/56 (7%)

Query: 227 DDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL 282
           D + EEE  E+ EE  +D  +   +D   DEE D G D++++T   KE   +++EL
Sbjct: 752 DAKVEEEPEEEPEETAEDTTEDTEQD--EDEEMDVGTDEEEET--AKESTAEKDEL 803


>gi|155722983 TNF receptor-associated protein 1 [Homo sapiens]
          Length = 704

 Score =  196 bits (498), Expect = 6e-50
 Identities = 115/421 (27%), Positives = 225/421 (53%), Gaps = 21/421 (4%)

Query: 276 YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFI 335
           Y++   +N  + IW  +P D+ + ++ EFY+ +    +      H+  +  L  R++ ++
Sbjct: 286 YLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYV 345

Query: 336 PRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREML 395
           P   P     +++  +++ LY R+V I     +++P++L FIRGVVDSED+PLN+SRE+L
Sbjct: 346 PDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELL 405

Query: 396 QQSKILKVIRKNIVKKCLELF-SELAEDKENYKKFYEAFSKNLKLGI--HEDSTNRRRLS 452
           Q+S +++ +R  + ++ ++ F  +  +D E Y KF+E +   ++ GI    +   +  ++
Sbjct: 406 QESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIA 465

Query: 453 ELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVV 511
           +LLRY +S     ++TSLSEY SRM+   ++IYY+   ++    +S + E ++K+  EV+
Sbjct: 466 KLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVL 525

Query: 512 YMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEE--------SKAKFENL 563
           +  E  DE  +  L+EFD K L+SV     ++  D  +++K E+        S+ + E L
Sbjct: 526 FCFEQFDELTLLHLREFDKKKLISVE---TDIVVDHYKEEKFEDRSPAAECLSEKETEEL 582

Query: 564 CKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAK 623
              M+ +L  +V  V ++ RL + P  +     G        ++ Q L         + +
Sbjct: 583 MAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQ 639

Query: 624 KHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRM 683
             LEINP H +++ L Q   ++      + LV  ++E A++++G  ++DP+    R+  +
Sbjct: 640 PTLEINPRHALIKKLNQLRASEPG--LAQLLVDQIYENAMIAAGL-VDDPRAMVGRLNEL 696

Query: 684 I 684
           +
Sbjct: 697 L 697



 Score =  178 bits (451), Expect = 2e-44
 Identities = 97/209 (46%), Positives = 143/209 (68%), Gaps = 11/209 (5%)

Query: 17  FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDII 76
           FQAE  +L+ ++  + YS KE+F+RELISNASDAL+K+R++ ++D   L    E++I + 
Sbjct: 90  FQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALP---EMEIHLQ 146

Query: 77  PNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS--MIGQFGVGFY 134
            N ++ T+T+ DTGIGMT+ +L++NLGTIA+SG+KAF++ALQ  A+ S  +IGQFGVGFY
Sbjct: 147 TNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFY 206

Query: 135 SAYLVAEKVVVITKHNDDEQ--YAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEY 192
           SA++VA++V V ++        Y W S   G F +    G  +  GTK+I+HLK D  E+
Sbjct: 207 SAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASG--VRTGTKIIIHLKSDCKEF 264

Query: 193 LEERRVKEVVKKHSQFIGYPITLYLEKER 221
             E RV++VV K+S F+ +P  LYL   R
Sbjct: 265 SSEARVRDVVTKYSNFVSFP--LYLNGRR 291


>gi|34878777 ring finger protein 20 [Homo sapiens]
          Length = 975

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 87/397 (21%), Positives = 169/397 (42%), Gaps = 61/397 (15%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           E+ERE+E  + E E E+ E+E+E + + EK K+++  S++E DS KDK+K       K  
Sbjct: 566 EEERERERREKERERER-EREKEKEREREKQKLKE--SEKERDSAKDKEKGKHDDGRK-- 620

Query: 278 DQEELNKTKPIWTRNPDDITQEE--YGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFI 335
            + E+ K   I  +   +  +E     + Y+S   +  D + +     + + E   L   
Sbjct: 621 KEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDL--- 677

Query: 336 PRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREML 395
            R+   DL E+K+KK N K+            E   EYL     +   E+        +L
Sbjct: 678 -RQRLKDL-EDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAKQEE------EALL 729

Query: 396 QQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGIHEDSTNRRRLSEL 454
            +  +     +++ ++ + L  +L E D  N+K   E    N             ++ +L
Sbjct: 730 SEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSN-------------QIHKL 776

Query: 455 LRYHTSQSGDEMTSLS-------EYVSRMKETQKSIYYITGESKEQVA-NSAFVERVRKR 506
           L+    +  D++ +L        + V +++E +  +    G  ++++   +  +E  +++
Sbjct: 777 LKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGEKELGLRTQALEMNKRK 836

Query: 507 GFEVVYMTEPID---EYCVQQLKEFDGKSLV-SVTKEG-----LELPEDEEEKKKMEESK 557
             E   + + +    E   ++L +F  + +  SVTKE          ED    ++  E+ 
Sbjct: 837 AMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDMFNFKRAQEDISRLRRKLETT 896

Query: 558 AKFENLCK----LMKEILDKKVEKVTISNRLVSSPCC 590
            K +N+ K    LM+EI D K          ++ PCC
Sbjct: 897 KKPDNVPKCDEILMEEIKDYKAR--------LTCPCC 925


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 48/166 (28%), Positives = 85/166 (51%), Gaps = 32/166 (19%)

Query: 184  HLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKD 243
            H  E+    L+E   +E +               E+ERE+E   +E EEE+  +EEE++ 
Sbjct: 2225 HFSEEMESLLDELEKQESLSSEE-----------EEEREEE---EEREEEEVREEEEERK 2270

Query: 244  DEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGE 303
            +EE+ + + V  +EE+   K KKKK KK KE+  ++EE+ + K       ++I  EE  E
Sbjct: 2271 EEEEGEEKQVEKEEEE---KKKKKKEKK-KEEVQEKEEVFEEK-------EEIMSEEETE 2319

Query: 304  FYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKK 349
               SL+++ E+    +  S+E +++ R    + +   F L E ++K
Sbjct: 2320 ---SLSDEEEEE---ESCSLEEEVD-REKEILKKEKQFKLQEQRRK 2358



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 23/97 (23%), Positives = 51/97 (52%), Gaps = 14/97 (14%)

Query: 218  EKEREKEISD-DEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIK--- 273
            +K +EK  S  DE E E+   EE +   +E  K E + S+EE++  ++++++ ++++   
Sbjct: 2207 DKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEE 2266

Query: 274  ----------EKYIDQEELNKTKPIWTRNPDDITQEE 300
                      EK +++EE  K K    +  +++ ++E
Sbjct: 2267 EERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE 2303


>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 27/71 (38%), Positives = 45/71 (63%), Gaps = 7/71 (9%)

Query: 210 GYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKT 269
           G P+     +E E+E+ ++E EEEK E EEE++ +EEK +      DEE++  + KK + 
Sbjct: 115 GLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEE------DEEEEEKEGKKMEE 168

Query: 270 KKIKEKYIDQE 280
           +K++E+ ID E
Sbjct: 169 EKVEEE-IDTE 178



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 19/65 (29%), Positives = 44/65 (67%), Gaps = 9/65 (13%)

Query: 231 EEEKGEKEEEDKDDEEKPKIEDVGSDEE------DDSGKDKKKKTKKIKEKYIDQE---E 281
           EEE+ E+EEE+ ++EEK + ++   +EE      ++  ++++K+ KK++E+ +++E   E
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178

Query: 282 LNKTK 286
           + +T+
Sbjct: 179 IQRTQ 183



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 22/62 (35%), Positives = 36/62 (58%), Gaps = 10/62 (16%)

Query: 185 LKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDD 244
           ++E++ E  EE + +E  +   +          EKE EKE  D+E EE++G+K EE+K +
Sbjct: 123 VEEEEEEVEEEEKEEEKEEDEEEE---------EKEEEKE-EDEEEEEKEGKKMEEEKVE 172

Query: 245 EE 246
           EE
Sbjct: 173 EE 174



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 18/68 (26%), Positives = 38/68 (55%), Gaps = 3/68 (4%)

Query: 217 LEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKY 276
           L   R   +  +E   ++G   EE++ +EE+ ++E+   +EE +  +++++K    +EK 
Sbjct: 97  LSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKE---EEKE 153

Query: 277 IDQEELNK 284
            D+EE  K
Sbjct: 154 EDEEEEEK 161


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 106/524 (20%), Positives = 210/524 (40%), Gaps = 51/524 (9%)

Query: 217  LEKEREKEISDDEAEEEKGEKEEEDKDDEEKPK------IED--VGSDEEDDSGKDKKKK 268
            LE+ ++K + D EA  ++ E++    D  EK K      ++D  V  D +     + +KK
Sbjct: 1390 LEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKK 1449

Query: 269  TKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLE 328
             KK  +   +++ ++  +    R+  +    E      SL    E+ L  K        +
Sbjct: 1450 QKKFDQLLAEEKSIS-ARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQ 1508

Query: 329  FRALLFIPRRAPFDLFEN----KKKKNNIKLYVR--RVFIMDSCDELIPEYLNFIRGVVD 382
             RA +     +  D+ +N    +K K  ++  V   R  + +  DEL       +R  V+
Sbjct: 1509 LRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVN 1568

Query: 383  SEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENY------KKFYEAFSKN 436
             + +     R++  + +  +  ++ ++K+  EL +EL ++++        KK  E   K+
Sbjct: 1569 MQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKD 1628

Query: 437  LKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSE-------YVSRMKETQKSIYYITGE 489
            L+  I   +  R  + + LR   +Q  D    L E         ++ KE++K +  +  E
Sbjct: 1629 LEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAE 1688

Query: 490  SKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLE--LPEDE 547
              +     A  ER R+      +  +  DE   +      GKS +   K  LE  + + E
Sbjct: 1689 ILQLQEELASSERARR------HAEQERDELADEITNSASGKSALLDEKRRLEARIAQLE 1742

Query: 548  EEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMK 607
            EE   +EE ++  E    L+ +   K   +V   N  +++       +      +ER  K
Sbjct: 1743 EE---LEEEQSNME----LLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNK 1795

Query: 608  AQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSG 667
                +     G + +K    I+     +  L ++ E +  ++A  + +V   E  L    
Sbjct: 1796 ELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIF 1855

Query: 668  FSLEDPQTHSNRI--------YRMIKLGLGIDEDEVAAEEPNAA 703
              +ED + H+++          RM +L   ++E E  A   NA+
Sbjct: 1856 MQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANAS 1899



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 96/519 (18%), Positives = 204/519 (39%), Gaps = 56/519 (10%)

Query: 221  REKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQE 280
            +EK++ +D   E   +  EE++  +   KI     ++++    D +++ KK +EK   ++
Sbjct: 999  KEKKLMEDRIAECSSQLAEEEEKAKNLAKIR----NKQEVMISDLEERLKK-EEK--TRQ 1051

Query: 281  ELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEG--------QLEFRAL 332
            EL K K        D+ Q++  E    + ++ +  LA K   ++G         L     
Sbjct: 1052 ELEKAKRKLDGETTDL-QDQIAELQAQI-DELKLQLAKKEEELQGALARGDDETLHKNNA 1109

Query: 333  LFIPRRAPFDL------FENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDL 386
            L + R     +      FE++K   N K   ++  + +  + L  E  + +      ++L
Sbjct: 1110 LKVVRELQAQIAELQEDFESEKASRN-KAEKQKRDLSEELEALKTELEDTLDTTAAQQEL 1168

Query: 387  PLNISREMLQQSKILKVIRKNIVKKCLEL-------FSELAEDKENYKKFYEAFSKNLKL 439
                 +E+ +  K L+   KN   +  ++         EL+E  E  K+F     KN K 
Sbjct: 1169 RTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKN-KQ 1227

Query: 440  GIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVAN--- 496
            G+  D+       ++L+   ++S  +   L   V  +         +  E  E+ +    
Sbjct: 1228 GLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQN 1287

Query: 497  -----SAFVERVRKRGFEVVYMTEPIDEYC--VQQLKEFDGKSLVSVTKEGLELPEDEEE 549
                 S  +E   K+G +       ++      Q+L + + +  ++++    +L   EEE
Sbjct: 1288 ELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQL---EEE 1344

Query: 550  KKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQ 609
            K  ++E + + E   K +++ +     ++  + + V      + S     A  + +  A+
Sbjct: 1345 KNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLE--EAKKKLLKDAE 1402

Query: 610  ALR---DNSTMGY---MMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETAL 663
            AL    +   + Y      K  L+   D   V+   Q+  A   +K  K    LL E   
Sbjct: 1403 ALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKS 1462

Query: 664  LSSGFSLEDPQTHS---NRIYRMIKLGLGIDEDEVAAEE 699
            +S+ ++ E  +  +    +  + + L   ++E   A EE
Sbjct: 1463 ISARYAEERDRAEAEAREKETKALSLARALEEALEAKEE 1501


>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
          Length = 1083

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 21/105 (20%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPK-------------IEDVGSDEE--DDSG 262
           EKE E E  ++E EEE+ ++EEE++DD+  PK             ++D   DE+  +D  
Sbjct: 37  EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGA 96

Query: 263 KDKKKKTKKIKEKYIDQEE--LNKTKPIWTRNPDDITQEEYGEFY 305
           +D  +K   I    +D++     + + +W     D  +EE GE+Y
Sbjct: 97  EDILEKASNIDNVVLDEDRSGARRLQNLWR----DQREEELGEYY 137



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 17/114 (14%)

Query: 218 EKEREKEISDDEAEEEK-----GEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTK-- 270
           + ER  +  + E +EE+      EKEEE +D+EE+ + E+   +EE++      KK +  
Sbjct: 14  DSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHG 73

Query: 271 -------KIKEKYIDQEEL-NKTKPIWTR--NPDDITQEEYGEFYKSLTNDWED 314
                   + ++Y D+++  +  + I  +  N D++  +E     + L N W D
Sbjct: 74  GFILDEADVDDEYEDEDQWEDGAEDILEKASNIDNVVLDEDRSGARRLQNLWRD 127


>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
           sapiens]
          Length = 1150

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 12/97 (12%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           +KE++K+   DE +++K  +E +D+ DE KPK    G D++    +D++KK  K K+   
Sbjct: 799 KKEKDKKSKKDERKDKK--EERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSK 856

Query: 278 DQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWED 314
           D +E            +D  Q+EY         D ED
Sbjct: 857 DDDE----------TEEDNNQDEYDPMEAEEAEDEED 883



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 21/71 (29%), Positives = 34/71 (47%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           +K ++    DDE EE+  + E +  + EE    ED   +EE     DK+   +  KE+  
Sbjct: 849 DKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPS 908

Query: 278 DQEELNKTKPI 288
             +E  KT+ I
Sbjct: 909 KDKEKEKTQMI 919



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 30/156 (19%), Positives = 74/156 (47%), Gaps = 6/156 (3%)

Query: 132 GFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSF---TVRADHGEPIGRGTKVILHLKED 188
           G +   +++  V++  +  D++++++E S         ++ D G  I    K +L L E 
Sbjct: 740 GKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRI---YKSLLSLPEK 796

Query: 189 QTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKP 248
           + +  ++++ K+  +K  +      T   + +R K   D + +E++ E+++EDK  ++  
Sbjct: 797 EDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSK 856

Query: 249 KIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNK 284
             ++   D   D     + +  + +E   D+EE+ K
Sbjct: 857 DDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTK 892



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 20/157 (12%)

Query: 139 VAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKEDQTEYLEERR 197
           + EK+    K  D EQ   E   G +  +    H   +   T  +  L+++    LE R 
Sbjct: 597 LVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKE----LESRA 652

Query: 198 VKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDE 257
           +     K SQ I   +T  L+ E +KE   ++ E EK EKEE D+DD+ K          
Sbjct: 653 LSSKGLK-SQLIAR-LTKQLKVEEQKE---EQKELEKSEKEE-DEDDDRK---------S 697

Query: 258 EDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPD 294
           EDD  ++++K+ ++I+ +  ++  +   +P    +P+
Sbjct: 698 EDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPN 734


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 33/122 (27%), Positives = 67/122 (54%), Gaps = 8/122 (6%)

Query: 183 LHLKEDQTEYLEER--RVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE 240
           +H +E++    EE+  R +E +++  +     I    EK RE+E    E EE+ GE+EE+
Sbjct: 566 MHDQEEKIREQEEKVWRQEEKIREQEE----KIREQEEKIREQEEMTQEQEEKMGEQEEK 621

Query: 241 DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL--NKTKPIWTRNPDDITQ 298
             + EEK + ++     +++  ++++KK ++ +EK  +QEE+   + + +W +      Q
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 681

Query: 299 EE 300
           EE
Sbjct: 682 EE 683



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 31/125 (24%), Positives = 65/125 (52%), Gaps = 9/125 (7%)

Query: 183 LHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDK 242
           +H +E++    EE+  ++  K H Q     I    EK   +E    E EE+  E+EE+ +
Sbjct: 545 IHEQEEKIRKQEEKMWRQEEKMHDQ--EEKIREQEEKVWRQEEKIREQEEKIREQEEKIR 602

Query: 243 DDEE--KPKIEDVGSDEE-----DDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDD 295
           + EE  + + E +G  EE     ++  +++++K ++ +EK  +QE+  + +    R  ++
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662

Query: 296 ITQEE 300
           + QE+
Sbjct: 663 MMQEQ 667



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 27/118 (22%), Positives = 60/118 (50%), Gaps = 14/118 (11%)

Query: 183 LHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDK 242
           +H +E   E  E+R+ +E +++             EK +E+E      EE+  E+EE+ +
Sbjct: 447 MHEQEKIREQEEKRQEEEKIREQ------------EKRQEQEAKMWRQEEKIREQEEKIR 494

Query: 243 DDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE 300
           + EEK   ++    E++   +++K++ +  +E +  +E++ + + IW +      QEE
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQ--EEMWRQEEKIREQEEIWRQKEKIHEQEE 550



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 24/108 (22%), Positives = 61/108 (56%), Gaps = 6/108 (5%)

Query: 194 EERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEK-GEKEEEDKDDEEKPKIED 252
           E+ +++E  K+  Q       ++ ++E+ +E  +   ++EK  E+EE+ +  EEK   ++
Sbjct: 509 EQEKIREEEKRQEQE-----EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQE 563

Query: 253 VGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE 300
               ++++  +++++K  + +EK  +QEE  + +    R  +++TQE+
Sbjct: 564 EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQ 611



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 64/374 (17%), Positives = 152/374 (40%), Gaps = 32/374 (8%)

Query: 204 KHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGK 263
           K  Q +   +   +E+       + + EE+   +EE+ ++ EEK         E+++  +
Sbjct: 333 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK-------IQEQEEKIR 385

Query: 264 DKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSV 323
           ++++K ++ +EK   QEE+   K    R  +++  E+  +  +     WE    ++    
Sbjct: 386 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 445

Query: 324 EGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDS 383
           +   + +      +R   +    ++K+   +  + R       +E I E    IR   + 
Sbjct: 446 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ------EEKIREQEEKIR---EQ 496

Query: 384 EDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHE 443
           E+       ++ +Q KI +  ++   ++      ++ E +E +++         K  IHE
Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ---------KEKIHE 547

Query: 444 DSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERV 503
                R+  E +     +  D+   + E   ++   ++ I     + +EQ       E +
Sbjct: 548 QEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEM 607

Query: 504 RKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENL 563
            +   E   M E  ++ C Q+ K  + +  +   +E +      E++KK+ E + K    
Sbjct: 608 TQEQEE--KMGEQEEKMCEQEEKMQEQEEKMRRQEEKI-----REQEKKIREQEEKIREQ 660

Query: 564 CKLMKEILDKKVEK 577
            ++M+E  +K  E+
Sbjct: 661 EEMMQEQEEKMWEQ 674



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 20/63 (31%), Positives = 39/63 (61%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           EK RE+E    E EE+  E+EE  ++ EEK   ++    E+++  +++++K ++ +EK  
Sbjct: 641 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 700

Query: 278 DQE 280
           +QE
Sbjct: 701 EQE 703



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 23/100 (23%), Positives = 57/100 (57%), Gaps = 13/100 (13%)

Query: 186 KEDQTEYLEERRVKEVVKK-HSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDD 244
           ++++  + +E +++E+ +K H Q          EK RE+E  +   EEEK  ++E+ ++ 
Sbjct: 428 RQEEMMWEKEEKIRELEEKMHEQ----------EKIREQE--EKRQEEEKIREQEKRQEQ 475

Query: 245 EEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNK 284
           E K   ++    E+++  +++++K  + +EK  +QE++ +
Sbjct: 476 EAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE 515



 Score = 33.9 bits (76), Expect = 0.55
 Identities = 25/102 (24%), Positives = 55/102 (53%), Gaps = 1/102 (0%)

Query: 183 LHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDK 242
           L+ ++++  + +E +++E  +K  Q     I    EK RE+E      EE   EKEE+ +
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEK-IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 413

Query: 243 DDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNK 284
             EE    ++     +++   +K++K ++++EK  +QE++ +
Sbjct: 414 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 455



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 24/96 (25%), Positives = 51/96 (53%), Gaps = 9/96 (9%)

Query: 186 KEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDE 245
           +E+ T+  EE+  ++  K   Q          EK +E+E      EE+  E+E++ ++ E
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQE---------EKMQEQEEKMRRQEEKIREQEKKIREQE 654

Query: 246 EKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEE 281
           EK + ++    E+++   ++++K  + +EK  +QEE
Sbjct: 655 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 690



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 21/82 (25%), Positives = 45/82 (54%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           EK R +E    E E++  E+EE+ ++ EE  + ++    E+++   ++++K ++ +EK  
Sbjct: 634 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 693

Query: 278 DQEELNKTKPIWTRNPDDITQE 299
            QEE    + +  R  ++  QE
Sbjct: 694 RQEEKMWEQEVRLRQQEEKMQE 715



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 20/86 (23%), Positives = 46/86 (53%)

Query: 196 RRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGS 255
           RR +E++ +  + +     +  EKE +    +++  E++  +E+E+K  EE+   E    
Sbjct: 413 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 472

Query: 256 DEEDDSGKDKKKKTKKIKEKYIDQEE 281
            E++     +++K ++ +EK  +QEE
Sbjct: 473 QEQEAKMWRQEEKIREQEEKIREQEE 498



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 26/110 (23%), Positives = 56/110 (50%), Gaps = 5/110 (4%)

Query: 173 EPIGRGTKVILHLKEDQTEYLEE-RRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAE 231
           E +G   + +   +E   E  E+ RR +E +++  +     I    EK RE+E    E E
Sbjct: 613 EKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEK----KIREQEEKIREQEEMMQEQE 668

Query: 232 EEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEE 281
           E+  E+EE+  + EEK + ++     +++   +++ + ++ +EK  + +E
Sbjct: 669 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 29/93 (31%), Positives = 54/93 (58%), Gaps = 12/93 (12%)

Query: 194 EERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDV 253
           E+R+ KE  KK         T   EK +EKE  + + + ++ +K+EE++ +EE+ + E+ 
Sbjct: 35  EKRKEKEKKKK---------TKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEE 85

Query: 254 GSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTK 286
             +EE + G+ +KKK K+ ++   ++EE  K K
Sbjct: 86  KEEEEKEEGRRRKKKKKRRRK---EEEEEKKKK 115



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 29/88 (32%), Positives = 53/88 (60%), Gaps = 9/88 (10%)

Query: 186 KEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDD- 244
           K+ +T+  E+R+ KE  +K  +          +K++E+E  ++E EEE+ EKEEE+K++ 
Sbjct: 42  KKKKTKETEKRKEKEEEEKKRK-------RKRKKKKEEEEREEEEEEEEEEKEEEEKEEG 94

Query: 245 -EEKPKIEDVGSDEEDDSGKDKKKKTKK 271
              K K +    +EE++  K +++KTKK
Sbjct: 95  RRRKKKKKRRRKEEEEEKKKKRRRKTKK 122



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 20/110 (18%)

Query: 188 DQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEED------ 241
           ++TE  EE   KE  +K  +          EK +EKE      E EK +++EE+      
Sbjct: 14  EETEETEEEEEKEGKRKEKR---------KEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64

Query: 242 -----KDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTK 286
                K++EE+ + E+   +E+++  K++ ++ KK K++   +EE  K K
Sbjct: 65  KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 6/86 (6%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           +K+++K+   +E EE +  +EEE+K+ + K K       +E    K+KKKKTK+ +++  
Sbjct: 1   KKKKKKKKETEETEETEETEEEEEKEGKRKEK------RKEKRKEKEKKKKTKETEKRKE 54

Query: 278 DQEELNKTKPIWTRNPDDITQEEYGE 303
            +EE  K K    +  ++  +EE  E
Sbjct: 55  KEEEEKKRKRKRKKKKEEEEREEEEE 80


>gi|148746183 ubiquitin specific protease 35 [Homo sapiens]
          Length = 1018

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 25/73 (34%), Positives = 47/73 (64%), Gaps = 5/73 (6%)

Query: 212 PITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKK 271
           P +LY+E    KE     ++EE+ E+EEE K  EE+ + E+VG +EE   G+ +++K ++
Sbjct: 654 PTSLYIEGLDSKEAGGQSSQEERIEREEEGK--EERTEKEEVGEEEESTRGEGEREKEEE 711

Query: 272 IKEKYIDQEELNK 284
           ++E   ++E++ K
Sbjct: 712 VEE---EEEKVEK 721



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 8/83 (9%)

Query: 187 EDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEE 246
           E + E  EER  KE V +  +      +   E EREKE  + E EEEK EKE E K+ E+
Sbjct: 678 EREEEGKEERTEKEEVGEEEE------STRGEGEREKE-EEVEEEEEKVEKETE-KEAEQ 729

Query: 247 KPKIEDVGSDEEDDSGKDKKKKT 269
           + + + +G+    D+     ++T
Sbjct: 730 EKEEDSLGAGTHPDAAIPSGERT 752



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 17/56 (30%), Positives = 34/56 (60%)

Query: 220 EREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEK 275
           ERE+E  ++  E+E+  +EEE    E + + E+   +EE+   K+ +K+ ++ KE+
Sbjct: 678 EREEEGKEERTEKEEVGEEEESTRGEGEREKEEEVEEEEEKVEKETEKEAEQEKEE 733


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 36/144 (25%), Positives = 66/144 (45%), Gaps = 22/144 (15%)

Query: 146  ITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKH 205
            ++  + ++    ES      +   D   P  R  K    L+E+Q  Y ++++ + +  + 
Sbjct: 1336 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA-ELEENQRSYKQKKKRRRIKVQE 1394

Query: 206  SQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDS---G 262
                        +   E + + +E EEEK E+EEE++++EE+ +      DE DDS   G
Sbjct: 1395 ------------DSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE------DENDDSKSPG 1436

Query: 263  KDKKKKTKKIKEKYIDQEELNKTK 286
            K +KK  K +K+  +  E  N  K
Sbjct: 1437 KGRKKIRKILKDDKLRTETQNALK 1460



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 37/146 (25%), Positives = 66/146 (45%), Gaps = 23/146 (15%)

Query: 226  SDDEAEEEK---GEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI----D 278
            SDDE EE K   G++ EE+  DEE     +  SD + +  K  + + + ++ K      +
Sbjct: 1254 SDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGE 1313

Query: 279  QEELNKTKP-----IWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALL 333
              E  KTKP     +  RN   ++ E+      S  +D+++    +  S E + E R   
Sbjct: 1314 SGEEKKTKPKEHKEVKGRNRRKVSSED------SEDSDFQESGVSEEVS-ESEDEQRPRT 1366

Query: 334  FIPRRAPFD----LFENKKKKNNIKL 355
               ++A  +     ++ KKK+  IK+
Sbjct: 1367 RSAKKAELEENQRSYKQKKKRRRIKV 1392



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 16/61 (26%), Positives = 34/61 (55%), Gaps = 5/61 (8%)

Query: 219  KEREKEISDDEAEEEKGEKEEEDKDDEEKPK-----IEDVGSDEEDDSGKDKKKKTKKIK 273
            K+ E+   D+EA+ +   + + D ++ +KP+     +    +  + +SG++KK K K+ K
Sbjct: 1267 KQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHK 1326

Query: 274  E 274
            E
Sbjct: 1327 E 1327



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 25/111 (22%), Positives = 53/111 (47%), Gaps = 9/111 (8%)

Query: 194  EERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEE-EDKDDEEKPKIED 252
            EE++ K   K+H +  G        ++   E S+D   +E G  EE  + +DE++P+   
Sbjct: 1316 EEKKTKP--KEHKEVKGRN-----RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRS 1368

Query: 253  VGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGE 303
                E +++ +  K+K K+ + K + ++  ++ K       ++  +EE  E
Sbjct: 1369 AKKAELEENQRSYKQKKKRRRIK-VQEDSSSENKSNSEEEEEEKEEEEEEE 1418



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 11/80 (13%)

Query: 216  YLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKK--------- 266
            +L+K++  E S+D+ ++ K   EE+ K  + K K+  +    E  S   +K         
Sbjct: 930  FLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICH 989

Query: 267  --KKTKKIKEKYIDQEELNK 284
              K  K+IK    D E+ +K
Sbjct: 990  FPKGIKQIKNGTTDGEKKSK 1009



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 5/51 (9%)

Query: 223  KEISDDEAEEEKGEKEEEDKDDEEKPKIED-----VGSDEEDDSGKDKKKK 268
            K+I +   + EK  K+  DK  ++K ++ D      G  +  DS +DKK K
Sbjct: 995  KQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSK 1045


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 36/144 (25%), Positives = 66/144 (45%), Gaps = 22/144 (15%)

Query: 146  ITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKH 205
            ++  + ++    ES      +   D   P  R  K    L+E+Q  Y ++++ + +  + 
Sbjct: 1374 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA-ELEENQRSYKQKKKRRRIKVQE 1432

Query: 206  SQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDS---G 262
                        +   E + + +E EEEK E+EEE++++EE+ +      DE DDS   G
Sbjct: 1433 ------------DSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE------DENDDSKSPG 1474

Query: 263  KDKKKKTKKIKEKYIDQEELNKTK 286
            K +KK  K +K+  +  E  N  K
Sbjct: 1475 KGRKKIRKILKDDKLRTETQNALK 1498



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 37/146 (25%), Positives = 66/146 (45%), Gaps = 23/146 (15%)

Query: 226  SDDEAEEEK---GEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI----D 278
            SDDE EE K   G++ EE+  DEE     +  SD + +  K  + + + ++ K      +
Sbjct: 1292 SDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGE 1351

Query: 279  QEELNKTKP-----IWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALL 333
              E  KTKP     +  RN   ++ E+      S  +D+++    +  S E + E R   
Sbjct: 1352 SGEEKKTKPKEHKEVKGRNRRKVSSED------SEDSDFQESGVSEEVS-ESEDEQRPRT 1404

Query: 334  FIPRRAPFD----LFENKKKKNNIKL 355
               ++A  +     ++ KKK+  IK+
Sbjct: 1405 RSAKKAELEENQRSYKQKKKRRRIKV 1430



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 16/61 (26%), Positives = 34/61 (55%), Gaps = 5/61 (8%)

Query: 219  KEREKEISDDEAEEEKGEKEEEDKDDEEKPK-----IEDVGSDEEDDSGKDKKKKTKKIK 273
            K+ E+   D+EA+ +   + + D ++ +KP+     +    +  + +SG++KK K K+ K
Sbjct: 1305 KQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHK 1364

Query: 274  E 274
            E
Sbjct: 1365 E 1365



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 25/111 (22%), Positives = 53/111 (47%), Gaps = 9/111 (8%)

Query: 194  EERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEE-EDKDDEEKPKIED 252
            EE++ K   K+H +  G        ++   E S+D   +E G  EE  + +DE++P+   
Sbjct: 1354 EEKKTKP--KEHKEVKGRN-----RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRS 1406

Query: 253  VGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGE 303
                E +++ +  K+K K+ + K + ++  ++ K       ++  +EE  E
Sbjct: 1407 AKKAELEENQRSYKQKKKRRRIK-VQEDSSSENKSNSEEEEEEKEEEEEEE 1456



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 11/80 (13%)

Query: 216  YLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKK--------- 266
            +L+K++  E S+D+ ++ K   EE+ K  + K K+  +    E  S   +K         
Sbjct: 968  FLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICH 1027

Query: 267  --KKTKKIKEKYIDQEELNK 284
              K  K+IK    D E+ +K
Sbjct: 1028 FPKGIKQIKNGTTDGEKKSK 1047



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 5/51 (9%)

Query: 223  KEISDDEAEEEKGEKEEEDKDDEEKPKIED-----VGSDEEDDSGKDKKKK 268
            K+I +   + EK  K+  DK  ++K ++ D      G  +  DS +DKK K
Sbjct: 1033 KQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSK 1083


>gi|38569484 kinesin family member 21A [Homo sapiens]
          Length = 1661

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 10/107 (9%)

Query: 186 KEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDE 245
           KED T+  +E++ ++ V +            LE E  +E+SD E EEE+ E+EE+D D  
Sbjct: 562 KEDNTDTDQEKKEEKGVSERENN-------ELEVEESQEVSDHEDEEEEEEEEEDDIDGG 614

Query: 246 EKPKIEDVGSDEEDDSGKDKKKKTKK--IKEKYIDQEELNKTKPIWT 290
           E     D  SDE+ +   D    T +  IK+K ID+ E N  K + T
Sbjct: 615 ESSDESDSESDEKANYQADLANITCEIAIKQKLIDELE-NSQKRLQT 660


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 27/96 (28%), Positives = 54/96 (56%), Gaps = 5/96 (5%)

Query: 220 EREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYID- 278
           E   E  D++ E+E+G++EEE++ +EE    ++ G D ED+  ++++++ ++ +E+  D 
Sbjct: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDH 171

Query: 279 QEELNKTKPIWTRNPDDITQEEYGEF----YKSLTN 310
           Q   + T+ +     DD   +EY  +     KSL N
Sbjct: 172 QMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLN 207



 Score = 36.6 bits (83), Expect = 0.084
 Identities = 25/104 (24%), Positives = 49/104 (47%), Gaps = 9/104 (8%)

Query: 212 PITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKK 271
           P  +  +     E  D +  E+  EKEE++ ++  +   E    DEED+ G   +++ ++
Sbjct: 77  PFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEG--DREEEEE 134

Query: 272 IKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 315
           I+E+  D +E  +       + +D  +EE  E  +    + EDH
Sbjct: 135 IEEEDEDDDEDGE-------DVEDEEEEEEEEEEEEEEEENEDH 171


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 31/117 (26%), Positives = 65/117 (55%), Gaps = 3/117 (2%)

Query: 186 KEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDE 245
           ++++  + +E +++E  +K  Q     I    EK RE+E    E EE+ GE+EE+  + E
Sbjct: 602 EQEEKMWKQEEKIREQEEK-IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 660

Query: 246 EKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL--NKTKPIWTRNPDDITQEE 300
           EK + ++     +++  ++++KK ++ +EK  +QEE+   + + +W +      QEE
Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 717



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 20/64 (31%), Positives = 42/64 (65%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           EK RE+E    E EE+  ++EE+ ++ EEK + ++    E+++  +++++ T++ +EK  
Sbjct: 591 EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG 650

Query: 278 DQEE 281
           +QEE
Sbjct: 651 EQEE 654



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 28/116 (24%), Positives = 59/116 (50%), Gaps = 10/116 (8%)

Query: 185 LKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDD 244
           ++E +  + EE ++ E  K   +          EK +E+E      EE+  E+EE+    
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEE----------EKRQEQEDKMWRQEEKIREQEEKVWRQ 589

Query: 245 EEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE 300
           EEK + ++    E+++    +++K ++ +EK  +QEE  + +    R  +++TQE+
Sbjct: 590 EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ 645



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 22/84 (26%), Positives = 50/84 (59%), Gaps = 1/84 (1%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           EK +E+E    + EE+  E+EE+ ++ EEK + ++    E+++  +++++K  + +EK  
Sbjct: 598 EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 657

Query: 278 DQEE-LNKTKPIWTRNPDDITQEE 300
           +QEE + + +    R  + I ++E
Sbjct: 658 EQEEKMQEQEETMWRQEEKIREQE 681



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 65/388 (16%), Positives = 171/388 (44%), Gaps = 52/388 (13%)

Query: 186 KEDQTEYLEERRVKEVVKK-HSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDD 244
           ++++  + +E +++E+ +K H Q          EK RE+E  +   EEEK  ++E+ ++ 
Sbjct: 381 RQEEMMWEKEEKIRELEEKMHEQ----------EKIREQE--EKRQEEEKIREQEKRQEQ 428

Query: 245 EEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL------NKTKPIWTRNPDDITQ 298
           E K   ++    E+++  ++++KK  + +EK  +QE++       + + +W R  + I +
Sbjct: 429 EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW-RQEEKIHE 487

Query: 299 EEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVR 358
           +E     K   ++ E+ +  +   V  Q E                E K ++   K++ +
Sbjct: 488 QEEIWRQKEKMHEQEEKIRKQEEKVWRQEE-----------KIREQEEKIREQEEKMWRQ 536

Query: 359 RVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSE 418
              I +  +    E     +  +  E+       +M +Q + ++   + + ++  ++  +
Sbjct: 537 EEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQ 596

Query: 419 LAEDKENYKKFYEAFSK---------NLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSL 469
             + +E  +K ++   K           +  I E     R   E+ +    + G++   +
Sbjct: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 656

Query: 470 SEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFD 529
            E   +M+E +++++    + +EQ       +++R++  ++    E + E   Q+ K ++
Sbjct: 657 CEQEEKMQEQEETMWRQEEKIREQ------EKKIREQEEKIREQEEMMQE---QEEKMWE 707

Query: 530 GKSLVSVTKEGLELPEDEEEKKKMEESK 557
            +  +   +E +   +++EEK + +E K
Sbjct: 708 QEEKMCEQEEKM---QEQEEKMRRQEEK 732



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 26/118 (22%), Positives = 61/118 (51%), Gaps = 14/118 (11%)

Query: 183 LHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDK 242
           +H +E   E  E+R+ +E +++             EK +E+E      EE+  E+EE+ +
Sbjct: 400 MHEQEKIREQEEKRQEEEKIREQ------------EKRQEQEAKMWRQEEKIREQEEKIR 447

Query: 243 DDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE 300
           + E+K   ++    E++   +++K++ +  +E +  +E++++ + IW +      QEE
Sbjct: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQ--EEMWRQEEKIHEQEEIWRQKEKMHEQEE 503



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 20/63 (31%), Positives = 39/63 (61%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           EK RE+E    E EE+  E+EE  ++ EEK   ++    E+++  +++++K ++ +EK  
Sbjct: 675 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734

Query: 278 DQE 280
           +QE
Sbjct: 735 EQE 737



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 23/105 (21%), Positives = 55/105 (52%), Gaps = 10/105 (9%)

Query: 185 LKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDD 244
           ++E++    +E   ++  K H Q     I    EK  E+E    + EE+   +EE+ ++ 
Sbjct: 466 IREEEKRQEQEEMWRQEEKIHEQ---EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQ 522

Query: 245 EEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIW 289
           EEK +       E+++    +++K ++ +E + ++E++++ + IW
Sbjct: 523 EEKIR-------EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIW 560



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 22/90 (24%), Positives = 49/90 (54%), Gaps = 8/90 (8%)

Query: 186 KEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDE 245
           ++++T + +E +++E  KK        I    EK RE+E    E EE+  E+EE+  + E
Sbjct: 665 EQEETMWRQEEKIREQEKK--------IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 716

Query: 246 EKPKIEDVGSDEEDDSGKDKKKKTKKIKEK 275
           EK + ++     +++   +++ + ++ +EK
Sbjct: 717 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 70/373 (18%), Positives = 155/373 (41%), Gaps = 35/373 (9%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           EK +E E    E EE+  E+EE+ ++ EEK + ++    E+++  + +++   + +EK  
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366

Query: 278 DQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPR 337
            QEE+   K    R  +++  E+  E  + L     +   ++    + Q E +       
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEK-EEKIRELEEKMHEQEKIREQEEKRQEEEKI------ 419

Query: 338 RAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQ 397
                  + K+++   K++ +        +E I E    IR   + E        ++ +Q
Sbjct: 420 -----REQEKRQEQEAKMWRQ--------EEKIREQEEKIR---EQEKKMWRQEEKIHEQ 463

Query: 398 SKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNR-----RRLS 452
            KI +  ++   ++      ++ E +E +++  +   +  K+   E+   R     R   
Sbjct: 464 EKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE 523

Query: 453 ELLRYHTSQSGDEMTSLSEYVSRMKETQK--SIYYITGESKEQVANSAF---VERVRKRG 507
           E +R    +   +   + E     +E +K      I  E K Q          E++R++ 
Sbjct: 524 EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE 583

Query: 508 FEVVYMTEPI--DEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCK 565
            +V    E I   E   Q+ +E   K    + ++  ++ E EE+ ++ EE   + E + +
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643

Query: 566 LMKEILDKKVEKV 578
             +E + ++ EK+
Sbjct: 644 EQEEKMGEQEEKM 656



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 24/105 (22%), Positives = 54/105 (51%), Gaps = 6/105 (5%)

Query: 196 RRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGS 255
           RR +E++ +  + +     +  EKE +    +++  E++  +E+E+K  EE+   E    
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 425

Query: 256 DEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE 300
            E++     +++K ++ +EK  +QE     K +W R  + I ++E
Sbjct: 426 QEQEAKMWRQEEKIREQEEKIREQE-----KKMW-RQEEKIHEQE 464



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 27/112 (24%), Positives = 55/112 (49%), Gaps = 15/112 (13%)

Query: 185 LKEDQTEYLEERRVKEVVKKHSQFIGY-----PITLYLEKEREKEIS----DDEAEEEKG 235
           ++E + +  EE +++E  K+  Q          I    EK RE+E      +++  E++ 
Sbjct: 406 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 465

Query: 236 EKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKK------KTKKIKEKYIDQEE 281
            +EEE + ++E+   ++    E+++  + K+K      K +K +EK   QEE
Sbjct: 466 IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE 517



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 23/101 (22%), Positives = 52/101 (51%), Gaps = 9/101 (8%)

Query: 183 LHLKEDQTEYLEER--RVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE 240
           +H +E++    EE+  R +E +++  + I        E+E +    +++  E++    EE
Sbjct: 498 MHEQEEKIRKQEEKVWRQEEKIREQEEKIR-------EQEEKMWRQEEKIREQEEMWREE 550

Query: 241 DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEE 281
           +K  E++   E+    E++D    +++K ++ +EK   QEE
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE 591


>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
          Length = 569

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 34/131 (25%), Positives = 69/131 (52%), Gaps = 8/131 (6%)

Query: 186 KEDQTEYLEERRVKEVVKK--HSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKD 243
           + +  EY  E   +E  +   HS+     +  + ++ +EKE  + + EEE  +KEE++++
Sbjct: 337 ESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEE 396

Query: 244 DEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGE 303
           +EE+ K ++   +EE+   K++++   K +E   D++E    KP      D  T+E YGE
Sbjct: 397 EEEEMKQKE---EEEEIRNKNEEEGESKDEE---DEDEDGGQKPEGEPQQDPGTEETYGE 450

Query: 304 FYKSLTNDWED 314
             +   ++ +D
Sbjct: 451 VEEEPLDEAQD 461


>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
           isoform b [Homo sapiens]
          Length = 1176

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 33/114 (28%), Positives = 56/114 (49%), Gaps = 6/114 (5%)

Query: 187 EDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEE 246
           +D + Y +   V E V   S+     +T  L +E E+E  ++E EEE+ E+EEE++D+E 
Sbjct: 268 DDFSLYYDSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEES 327

Query: 247 KPKIEDVGSDEEDDSGKDK-KKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQE 299
             +     SD    SG+ K KKK +K         +  K +P   + P  ++ +
Sbjct: 328 GNQ-----SDRSGSSGRRKAKKKWRKDSPWVKPSRKRRKREPPRAKEPRGVSND 376



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 16/44 (36%), Positives = 24/44 (54%)

Query: 518 DEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFE 561
           D Y V +  + D KS V    E L   E+EEE+++ EE + + E
Sbjct: 275 DSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEE 318


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 19/47 (40%), Positives = 35/47 (74%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKD 264
           E+E E+E  +DE EEE+ E+EEE++++EE+ + E+   +EE+++  D
Sbjct: 264 EEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPD 310



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 26/98 (26%), Positives = 55/98 (56%), Gaps = 3/98 (3%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           E+E E+E  ++E EEE  E+EEE++++EE+ + E+   +EE++  ++++     I ++  
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQE-- 315

Query: 278 DQEELNKTKPIWTRNPDDIT-QEEYGEFYKSLTNDWED 314
           D    +  K    R P+  + + EY    +  ++D +D
Sbjct: 316 DTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKD 353



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 20/69 (28%), Positives = 45/69 (65%), Gaps = 3/69 (4%)

Query: 217 LEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKY 276
           L  E E E  ++E EEE+ ++EEE++++EE+ + E+   +EE++  ++++++ ++     
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEE---EEEEEEEEEEEEEEEEAAPDV 311

Query: 277 IDQEELNKT 285
           I QE+ + T
Sbjct: 312 IFQEDTSHT 320



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 19/78 (24%), Positives = 49/78 (62%), Gaps = 2/78 (2%)

Query: 223 KEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL 282
           ++ + +E+ ++KG    E++D+EE+ + E+   DEE++  ++++++ ++ +E+  ++EE 
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300

Query: 283 NKTKPIWTRNPDDITQEE 300
            + +      PD I QE+
Sbjct: 301 EEEEE--EAAPDVIFQED 316



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 15/58 (25%), Positives = 41/58 (70%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEK 275
           E  ++K I   E E+E+ E+EEE+++++E+ + E+   +EE++  ++++++ ++ +E+
Sbjct: 247 ESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304


>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 2/97 (2%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           EKE E E  ++E EEE+ ++EEE++DD+  PK    G    D++  D + + +   E   
Sbjct: 37  EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED-- 94

Query: 278 DQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWED 314
             E++ + + I   N D++  +E     + L N W D
Sbjct: 95  GAEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRD 131


>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 2/97 (2%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           EKE E E  ++E EEE+ ++EEE++DD+  PK    G    D++  D + + +   E   
Sbjct: 37  EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED-- 94

Query: 278 DQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWED 314
             E++ + + I   N D++  +E     + L N W D
Sbjct: 95  GAEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRD 131


>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 2/97 (2%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           EKE E E  ++E EEE+ ++EEE++DD+  PK    G    D++  D + + +   E   
Sbjct: 37  EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED-- 94

Query: 278 DQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWED 314
             E++ + + I   N D++  +E     + L N W D
Sbjct: 95  GAEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRD 131


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 45/175 (25%), Positives = 76/175 (43%), Gaps = 21/175 (12%)

Query: 186 KEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKE-----ISDDEAEEEKGEKEEE 240
           K+ + +  E+ RVKE  ++  +          EKEREKE       D + E EK  ++++
Sbjct: 378 KDTREKIKEKERVKEKDREKER--------EREKEREKEKERGKNKDRDKEREKDREKDK 429

Query: 241 DKDDE-EKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQE 299
           +KD E E+ K  +   D+E +  +DK+K+ +K + K ID++     K   +R P      
Sbjct: 430 EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK---SRTP----PR 482

Query: 300 EYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIK 354
            Y    +S ++  E        S       + +     R+P     NKK K   K
Sbjct: 483 SYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 537



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 21/87 (24%), Positives = 44/87 (50%), Gaps = 13/87 (14%)

Query: 194 EERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDV 253
           + RR K   KK S+           +ER K  S   + +++ +  E+ K   EK ++++ 
Sbjct: 347 DRRRSKSPHKKRSK----------SRERRKSRSRSHSRDKRKDTREKIK---EKERVKEK 393

Query: 254 GSDEEDDSGKDKKKKTKKIKEKYIDQE 280
             ++E +  K+++K+ ++ K K  D+E
Sbjct: 394 DREKEREREKEREKEKERGKNKDRDKE 420


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 45/175 (25%), Positives = 76/175 (43%), Gaps = 21/175 (12%)

Query: 186 KEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKE-----ISDDEAEEEKGEKEEE 240
           K+ + +  E+ RVKE  ++  +          EKEREKE       D + E EK  ++++
Sbjct: 262 KDTREKIKEKERVKEKDREKER--------EREKEREKEKERGKNKDRDKEREKDREKDK 313

Query: 241 DKDDE-EKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQE 299
           +KD E E+ K  +   D+E +  +DK+K+ +K + K ID++     K   +R P      
Sbjct: 314 EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK---SRTP----PR 366

Query: 300 EYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIK 354
            Y    +S ++  E        S       + +     R+P     NKK K   K
Sbjct: 367 SYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 421



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 21/87 (24%), Positives = 44/87 (50%), Gaps = 13/87 (14%)

Query: 194 EERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDV 253
           + RR K   KK S+           +ER K  S   + +++ +  E+ K   EK ++++ 
Sbjct: 231 DRRRSKSPHKKRSK----------SRERRKSRSRSHSRDKRKDTREKIK---EKERVKEK 277

Query: 254 GSDEEDDSGKDKKKKTKKIKEKYIDQE 280
             ++E +  K+++K+ ++ K K  D+E
Sbjct: 278 DREKEREREKEREKEKERGKNKDRDKE 304


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 28/103 (27%), Positives = 57/103 (55%), Gaps = 5/103 (4%)

Query: 185 LKEDQTEYLEERRVKEVVKKHSQFIGY-----PITLYLEKEREKEISDDEAEEEKGEKEE 239
           ++E + +  EE +++E  K+  Q          I    EK RE+E    E EE+ GE+EE
Sbjct: 359 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 418

Query: 240 EDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL 282
           +  + EE+ + ++     +++  ++++KK ++ +EK  +QEE+
Sbjct: 419 KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 461



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 33/131 (25%), Positives = 68/131 (51%), Gaps = 7/131 (5%)

Query: 173 EPIGRGTKVILHLKEDQTEYLEE-RRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAE 231
           E +G   + +   +E+  E  E+ RR +E +++  +     I    EK RE+E    E E
Sbjct: 411 EKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK----KIREQEEKIREQEEMMQEQE 466

Query: 232 EEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL--NKTKPIW 289
           E+ GE+E +  + E K + ++     +++  ++++KK ++ +EK  +QEE+   + + +W
Sbjct: 467 EKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 526

Query: 290 TRNPDDITQEE 300
            +      QEE
Sbjct: 527 EQEEKMCEQEE 537



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 20/63 (31%), Positives = 39/63 (61%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           EK RE+E    E EE+  E+EE  ++ EEK   ++    E+++  +++++K ++ +EK  
Sbjct: 495 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR 554

Query: 278 DQE 280
           +QE
Sbjct: 555 EQE 557



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 21/82 (25%), Positives = 46/82 (56%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           EK R +E    E E++  E+EE+ ++ EE  + ++    E+++   ++++K ++ +EK  
Sbjct: 488 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 547

Query: 278 DQEELNKTKPIWTRNPDDITQE 299
            QEE  + + +  R  ++  QE
Sbjct: 548 RQEEKMREQEVRLRQQEEKMQE 569



 Score = 33.9 bits (76), Expect = 0.55
 Identities = 27/128 (21%), Positives = 62/128 (48%), Gaps = 14/128 (10%)

Query: 187 EDQTEYLEE-----RRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEED 241
           ++Q E + E     RR +E++ +  + +     +  EKE +    +++  E++  +E+E+
Sbjct: 305 QEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 364

Query: 242 KDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL---------NKTKPIWTRN 292
           K  EE+   E     E++     +++K ++ +EK  +QEE+          + + +W + 
Sbjct: 365 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQE 424

Query: 293 PDDITQEE 300
            +   QEE
Sbjct: 425 EEMQEQEE 432



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 18/67 (26%), Positives = 40/67 (59%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           EK +E+E    E EE+  E+EE+ +  EE    ++     +++   +K++K ++++EK  
Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 354

Query: 278 DQEELNK 284
           +QE++ +
Sbjct: 355 EQEKIRE 361



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 18/79 (22%), Positives = 45/79 (56%)

Query: 222 EKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEE 281
           E+E    E EE+   +EE+ ++ E+K + ++    E+++  +++++K  + +EK  +QEE
Sbjct: 478 EQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 537

Query: 282 LNKTKPIWTRNPDDITQEE 300
             + +    R  ++  +E+
Sbjct: 538 KMQEQEEKMRRQEEKMREQ 556



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 22/96 (22%), Positives = 47/96 (48%)

Query: 218 EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
           EK R +E    E E++  E+EE+ ++ EE  + ++    E++    +++ K ++ +EK  
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMR 491

Query: 278 DQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWE 313
            QEE  + +    R  ++  +E+     +     WE
Sbjct: 492 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 527



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 23/97 (23%), Positives = 55/97 (56%), Gaps = 5/97 (5%)

Query: 188 DQTEYLEERRVKEVVKKHSQFIGYPITLYLEKE---REKEISDDEAEEEKGEKEEEDKDD 244
           +Q E + E+  +E++++  + +G       E+E   +E+E      EE+  E+E++ ++ 
Sbjct: 450 EQEEKIREQ--EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQ 507

Query: 245 EEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEE 281
           EEK + ++    E+++   ++++K  + +EK  +QEE
Sbjct: 508 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 544


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 33/119 (27%), Positives = 58/119 (48%), Gaps = 7/119 (5%)

Query: 181 VILHLKEDQTEYLE--ERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKE 238
           V  H+K    E ++  E+  KE V    Q     +T  + +E EKE  ++E +EE+G +E
Sbjct: 432 VSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEE 491

Query: 239 EEDKDDEEK---PKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPD 294
           EE +  EE+   P  E+  S E++     K++     + K  ++EE     P   ++P+
Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK--SPAEVKSPE 548



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 38/136 (27%), Positives = 62/136 (45%), Gaps = 12/136 (8%)

Query: 185 LKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEK-----EREKEISDDEAEEEKGEKEE 239
           LKED     +E   KE VK   +    P  + +++     E EK  +  + EE+K  K+E
Sbjct: 803 LKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE 862

Query: 240 E-DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL---NKTKPIWTRNPDD 295
           E  K +  KPK+E+    +E    K K+ K +  KE+  D++++    K  P      +D
Sbjct: 863 EAPKKEAPKPKVEE---KKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED 919

Query: 296 ITQEEYGEFYKSLTND 311
              +E  E  K   +D
Sbjct: 920 AKPKEKTEVAKKEPDD 935



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 7/117 (5%)

Query: 189 QTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKP 248
           + E  +E +VKE  KK  +          EK+  K+    + E  K + EE+ +   EKP
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP 885

Query: 249 KIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKP-----IWTRNPDDITQEE 300
           K   V + +E+   +DKKK     KE     E     KP     +  + PDD   +E
Sbjct: 886 KESKVEAKKEE--AEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 3/66 (4%)

Query: 219  KEREKEISDDEAEEEKGE-KEEEDKDDEEKPKIEDVGSDEEDDSGKD--KKKKTKKIKEK 275
            KE  K     EA  EK + KEE+ K  EEKPK E    +++    K+  K K  K  K  
Sbjct: 939  KEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSS 998

Query: 276  YIDQEE 281
              DQ++
Sbjct: 999  STDQKD 1004



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 21/89 (23%), Positives = 45/89 (50%), Gaps = 3/89 (3%)

Query: 218 EKEREKEISDDEAEEEKGEKE---EEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKE 274
           + E+E  I +++ EE +  +E   EE+K+ +E+   E+ G +EE+  G +++ K+   +E
Sbjct: 449 KSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEE 508

Query: 275 KYIDQEELNKTKPIWTRNPDDITQEEYGE 303
               ++E         ++P +    E  E
Sbjct: 509 AASPEKEAKSPVKEEAKSPAEAKSPEKEE 537


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 8/94 (8%)

Query: 218  EKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI 277
            +K  ++E S+DE+ EE+ E++EE+ + E K     +  +++DD G+DK K  K+      
Sbjct: 1504 QKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKR------ 1557

Query: 278  DQEELNKTKPIWTRNPDDITQEEYGEFYKSLTND 311
                  K KP+ +    D  Q+E  +   S T+D
Sbjct: 1558 --PNRGKAKPVVSDFDSDEEQDEREQSEGSGTDD 1589



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 35/139 (25%), Positives = 61/139 (43%), Gaps = 15/139 (10%)

Query: 148 KHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVI-LHLKEDQTEY------LEERRVKE 200
           K    ++ A E++ GG   +  D GEPI   +++  L +K   TE        E  +  +
Sbjct: 558 KRRRRKKKAEENAEGGESALGPD-GEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQ 616

Query: 201 VVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDD 260
           +        GY +        + E SD + EEE  E+E   ++ EEK  ++    + E+ 
Sbjct: 617 LDAWLEMNPGYEVA----PRSDSEESDSDYEEEDEEEESSRQETEEKILLD---PNSEEV 669

Query: 261 SGKDKKKKTKKIKEKYIDQ 279
           S KD K+  +  K+   D+
Sbjct: 670 SEKDAKQIIETAKQDVDDE 688


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,262,284
Number of Sequences: 37866
Number of extensions: 1268264
Number of successful extensions: 26059
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 527
Number of HSP's successfully gapped in prelim test: 463
Number of HSP's that attempted gapping in prelim test: 9585
Number of HSP's gapped (non-prelim): 8313
length of query: 724
length of database: 18,247,518
effective HSP length: 110
effective length of query: 614
effective length of database: 14,082,258
effective search space: 8646506412
effective search space used: 8646506412
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.