Guide to the Human Genome
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Search of human proteins with 20149565

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20149565 small inducible cytokine B14 precursor [Homo
sapiens]
         (111 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20149565 small inducible cytokine B14 precursor [Homo sapiens]     230   2e-61
gi|4504155 chemokine (C-X-C motif) ligand 2 [Homo sapiens]             51   2e-07
gi|4504153 chemokine (C-X-C motif) ligand 1 [Homo sapiens]             47   3e-06
gi|54144650 chemokine (C-X-C motif) ligand 3 [Homo sapiens]            47   4e-06
gi|4505735 platelet factor 4 variant 1 [Homo sapiens]                  34   0.022
gi|4506851 chemokine (C-X-C motif) ligand 6 (granulocyte chemota...    34   0.029
gi|5174671 chemokine (C-C motif) ligand 26 precursor [Homo sapiens]    33   0.049
gi|4505733 platelet factor 4 (chemokine (C-X-C motif) ligand 4) ...    33   0.064
gi|4505981 pro-platelet basic protein precursor [Homo sapiens]         32   0.14 
gi|4503825 frizzled 1 [Homo sapiens]                                   30   0.32 
gi|170932505 neuromedin U receptor 2 [Homo sapiens]                    28   1.2  
gi|116235482 glycosyltransferase-like 1B [Homo sapiens]                27   2.7  
gi|4506291 protein tyrosine phosphatase, non-receptor type 2 iso...    27   4.6  
gi|18104982 protein tyrosine phosphatase, non-receptor type 2 [H...    27   4.6  
gi|18104980 protein tyrosine phosphatase, non-receptor type 2 is...    27   4.6  
gi|46909592 a disintegrin and metalloproteinase domain 15 isofor...    26   6.0  
gi|27436910 partner and localizer of BRCA2 [Homo sapiens]              26   7.8  
gi|241982802 HMG box domain containing 3 [Homo sapiens]                26   7.8  
gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent R...    26   7.8  
gi|22165427 small inducible cytokine A24 precursor [Homo sapiens]      26   7.8  

>gi|20149565 small inducible cytokine B14 precursor [Homo sapiens]
          Length = 111

 Score =  230 bits (587), Expect = 2e-61
 Identities = 111/111 (100%), Positives = 111/111 (100%)

Query: 1   MSLLPRRAPPVSMRLLAAALLLLLLALYTARVDGSKCKCSRKGPKIRYSDVKKLEMKPKY 60
           MSLLPRRAPPVSMRLLAAALLLLLLALYTARVDGSKCKCSRKGPKIRYSDVKKLEMKPKY
Sbjct: 1   MSLLPRRAPPVSMRLLAAALLLLLLALYTARVDGSKCKCSRKGPKIRYSDVKKLEMKPKY 60

Query: 61  PHCEEKMVIITTKSVSRYRGQEHCLHPKLQSTKRFIKWYNAWNEKRRVYEE 111
           PHCEEKMVIITTKSVSRYRGQEHCLHPKLQSTKRFIKWYNAWNEKRRVYEE
Sbjct: 61  PHCEEKMVIITTKSVSRYRGQEHCLHPKLQSTKRFIKWYNAWNEKRRVYEE 111


>gi|4504155 chemokine (C-X-C motif) ligand 2 [Homo sapiens]
          Length = 107

 Score = 51.2 bits (121), Expect = 2e-07
 Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 11/96 (11%)

Query: 8  APPVSMRLLAAALLLLLLALYTARVDGS------KCKCSRKGPKIRYSDVKKLEMKPKYP 61
          A P + RLL  ALLLLLL   + R  G+      +C+C +    I   +++ +++K   P
Sbjct: 8  AAPSNPRLLRVALLLLLLVAASRRAAGAPLATELRCQCLQTLQGIHLKNIQSVKVKSPGP 67

Query: 62 HCEEKMVIITTKSVSRYRGQEHCLHPKLQSTKRFIK 97
          HC +  VI T K+     GQ+ CL+P     K+ I+
Sbjct: 68 HCAQTEVIATLKN-----GQKACLNPASPMVKKIIE 98


>gi|4504153 chemokine (C-X-C motif) ligand 1 [Homo sapiens]
          Length = 107

 Score = 47.0 bits (110), Expect = 3e-06
 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 11/96 (11%)

Query: 8  APPVSMRLLAAALLLLLLALYTARVDGS------KCKCSRKGPKIRYSDVKKLEMKPKYP 61
          A P + RLL  ALLLLLL     R  G+      +C+C +    I   +++ + +K   P
Sbjct: 8  AAPSNPRLLRVALLLLLLVAAGRRAAGASVATELRCQCLQTLQGIHPKNIQSVNVKSPGP 67

Query: 62 HCEEKMVIITTKSVSRYRGQEHCLHPKLQSTKRFIK 97
          HC +  VI T K+     G++ CL+P     K+ I+
Sbjct: 68 HCAQTEVIATLKN-----GRKACLNPASPIVKKIIE 98


>gi|54144650 chemokine (C-X-C motif) ligand 3 [Homo sapiens]
          Length = 107

 Score = 46.6 bits (109), Expect = 4e-06
 Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 11/96 (11%)

Query: 8  APPVSMRLLAAALLLLLLALYTARVDGS------KCKCSRKGPKIRYSDVKKLEMKPKYP 61
          A P + RLL  ALLLLLL   + R  G+      +C+C +    I   +++ + ++   P
Sbjct: 8  AAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHLKNIQSVNVRSPGP 67

Query: 62 HCEEKMVIITTKSVSRYRGQEHCLHPKLQSTKRFIK 97
          HC +  VI T K+     G++ CL+P     ++ I+
Sbjct: 68 HCAQTEVIATLKN-----GKKACLNPASPMVQKIIE 98


>gi|4505735 platelet factor 4 variant 1 [Homo sapiens]
          Length = 104

 Score = 34.3 bits (77), Expect = 0.022
 Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 10/88 (11%)

Query: 15 LLAAALLLLLLALYTARVDGSK-----CKCSRKGPKIRYSDVKKLEMKPKYPHCEEKMVI 69
          +L  ALLLL + +  AR +  +     C C +   ++R   +  LE+    PHC    +I
Sbjct: 17 MLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLI 76

Query: 70 ITTKSVSRYRGQEHCLHPKLQSTKRFIK 97
           T K+     G++ CL  +    K+ IK
Sbjct: 77 ATLKN-----GRKICLDLQALLYKKIIK 99


>gi|4506851 chemokine (C-X-C motif) ligand 6 (granulocyte
           chemotactic protein 2) [Homo sapiens]
          Length = 114

 Score = 33.9 bits (76), Expect = 0.029
 Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 14/100 (14%)

Query: 7   RAPPVSMRLLAAALLLLLLAL---------YTARVDGSKCKCSRKGPKIRYSDVKKLEMK 57
           R P  S  L A   LLLLL            +A +   +C C R   ++    + KL++ 
Sbjct: 10  RVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNPKTIGKLQVF 69

Query: 58  PKYPHCEEKMVIITTKSVSRYRGQEHCLHPKLQSTKRFIK 97
           P  P C +  V+ + K+     G++ CL P+    K+ I+
Sbjct: 70  PAGPQCSKVEVVASLKN-----GKQVCLDPEAPFLKKVIQ 104


>gi|5174671 chemokine (C-C motif) ligand 26 precursor [Homo
          sapiens]
          Length = 94

 Score = 33.1 bits (74), Expect = 0.049
 Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 8/83 (9%)

Query: 15 LLAAALLLLLLALYTARVDGSKCKCSRKGPK-IRYSDVKKLEMKPKYPHCEEKMVIITTK 73
          +L A+LL L L   T   D SK  C +   K + ++ V+  E       C ++ VI TTK
Sbjct: 10 VLLASLLSLHLGTATRGSDISKTCCFQYSHKPLPWTWVRSYEFTSN--SCSQRAVIFTTK 67

Query: 74 SVSRYRGQEHCLHPKLQSTKRFI 96
               RG++ C HP+ +  +++I
Sbjct: 68 -----RGKKVCTHPRKKWVQKYI 85


>gi|4505733 platelet factor 4 (chemokine (C-X-C motif) ligand 4)
          [Homo sapiens]
          Length = 101

 Score = 32.7 bits (73), Expect = 0.064
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 10/88 (11%)

Query: 15 LLAAALLLLLLALYTARVDGSK-----CKCSRKGPKIRYSDVKKLEMKPKYPHCEEKMVI 69
          LL   LLLL L +  A  +  +     C C +   ++R   +  LE+    PHC    +I
Sbjct: 14 LLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLI 73

Query: 70 ITTKSVSRYRGQEHCLHPKLQSTKRFIK 97
           T K+     G++ CL  +    K+ IK
Sbjct: 74 ATLKN-----GRKICLDLQAPLYKKIIK 96


>gi|4505981 pro-platelet basic protein precursor [Homo sapiens]
          Length = 128

 Score = 31.6 bits (70), Expect = 0.14
 Identities = 17/62 (27%), Positives = 29/62 (46%), Gaps = 5/62 (8%)

Query: 36  KCKCSRKGPKIRYSDVKKLEMKPKYPHCEEKMVIITTKSVSRYRGQEHCLHPKLQSTKRF 95
           +C C +    I   +++ LE+  K  HC +  VI T K      G++ CL P     K+ 
Sbjct: 62  RCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKD-----GRKICLDPDAPRIKKI 116

Query: 96  IK 97
           ++
Sbjct: 117 VQ 118


>gi|4503825 frizzled 1 [Homo sapiens]
          Length = 647

 Score = 30.4 bits (67), Expect = 0.32
 Identities = 17/39 (43%), Positives = 22/39 (56%)

Query: 6  RRAPPVSMRLLAAALLLLLLALYTARVDGSKCKCSRKGP 44
          RR PPV  R LA  LLLLL  L    + G + + + +GP
Sbjct: 41 RRRPPVDPRRLARQLLLLLWLLEAPLLLGVRAQAAGQGP 79


>gi|170932505 neuromedin U receptor 2 [Homo sapiens]
          Length = 415

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/32 (46%), Positives = 18/32 (56%)

Query: 63  CEEKMVIITTKSVSRYRGQEHCLHPKLQSTKR 94
           C   ++ ITT SV RY    H    KLQST+R
Sbjct: 130 CFASILSITTVSVERYVAILHPFRAKLQSTRR 161


>gi|116235482 glycosyltransferase-like 1B [Homo sapiens]
          Length = 721

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 4/42 (9%)

Query: 3  LLPRRAPPVSMRLLAAALLLLLLALYTARVDGSKCKCSRKGP 44
          +LPR  P    R L AA LLLLL L    + G    C R+ P
Sbjct: 1  MLPRGRP----RALGAAALLLLLLLLGFLLFGGDLGCERREP 38


>gi|4506291 protein tyrosine phosphatase, non-receptor type 2
           isoform 1 [Homo sapiens]
          Length = 415

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 10/41 (24%), Positives = 22/41 (53%)

Query: 28  YTARVDGSKCKCSRKGPKIRYSDVKKLEMKPKYPHCEEKMV 68
           Y A ++G+KC       + R+ ++ K ++ P + H   K++
Sbjct: 269 YMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIM 309


>gi|18104982 protein tyrosine phosphatase, non-receptor type 2 [Homo
           sapiens]
          Length = 353

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 10/41 (24%), Positives = 22/41 (53%)

Query: 28  YTARVDGSKCKCSRKGPKIRYSDVKKLEMKPKYPHCEEKMV 68
           Y A ++G+KC       + R+ ++ K ++ P + H   K++
Sbjct: 269 YMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIM 309


>gi|18104980 protein tyrosine phosphatase, non-receptor type 2
           isoform 2 [Homo sapiens]
          Length = 387

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 10/41 (24%), Positives = 22/41 (53%)

Query: 28  YTARVDGSKCKCSRKGPKIRYSDVKKLEMKPKYPHCEEKMV 68
           Y A ++G+KC       + R+ ++ K ++ P + H   K++
Sbjct: 269 YMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIM 309


>gi|46909592 a disintegrin and metalloproteinase domain 15 isoform 1
           preproprotein [Homo sapiens]
          Length = 772

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 16/51 (31%), Positives = 24/51 (47%)

Query: 13  MRLLAAALLLLLLALYTARVDGSKCKCSRKGPKIRYSDVKKLEMKPKYPHC 63
           + LL   +L++L A Y  R    +  C  KGP  +YS   +    P+  HC
Sbjct: 700 LSLLVLLVLVMLGASYWYRARLHQRLCQLKGPTCQYSLRGQPSPHPQGSHC 750


>gi|27436910 partner and localizer of BRCA2 [Homo sapiens]
          Length = 1186

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 4/61 (6%)

Query: 38  KCSRKGPKIRYSDVKKLEMKPKYPHCEEKMVIITTKSVSRY-RGQEHCLHPKLQSTKRFI 96
           K   + P  RY+  +K    P   HCE    ++ T S+S   R +E     K Q  K FI
Sbjct: 502 KAVAQAPGRRYTGKRKSACTPASDHCEP---LLPTSSLSIVNRSKEEVTSHKYQHEKLFI 558

Query: 97  K 97
           +
Sbjct: 559 Q 559


>gi|241982802 HMG box domain containing 3 [Homo sapiens]
          Length = 1292

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 14/46 (30%), Positives = 23/46 (50%), Gaps = 1/46 (2%)

Query: 43  GPKIRYSDVKKLEMKP-KYPHCEEKMVIITTKSVSRYRGQEHCLHP 87
           GP  R S VK +E+KP  +P  +    +     ++  RG+  C +P
Sbjct: 582 GPSNRTSQVKVVEVKPDMFPPYKYSCTVTLDLGLATSRGRGKCKNP 627


>gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac
           exchange factor 1 [Homo sapiens]
          Length = 1659

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 12/30 (40%), Positives = 17/30 (56%)

Query: 82  EHCLHPKLQSTKRFIKWYNAWNEKRRVYEE 111
           E+CLHP+ QS       +  + +K  VYEE
Sbjct: 118 EYCLHPEPQSQHELGNVFLKFKDKFCVYEE 147


>gi|22165427 small inducible cytokine A24 precursor [Homo sapiens]
          Length = 119

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 5/43 (11%)

Query: 63  CEEKMVIITTKSVSRYRGQEHCLHPKLQSTKRFIKWYNAWNEK 105
           C +  VI TTK     +GQ+ C  PK +  +R++K  +A  +K
Sbjct: 58  CLKAGVIFTTK-----KGQQFCGDPKQEWVQRYMKNLDAKQKK 95


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.134    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,317,699
Number of Sequences: 37866
Number of extensions: 154455
Number of successful extensions: 445
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 428
Number of HSP's gapped (non-prelim): 20
length of query: 111
length of database: 18,247,518
effective HSP length: 81
effective length of query: 30
effective length of database: 15,180,372
effective search space: 455411160
effective search space used: 455411160
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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