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Search of human proteins with 20070331
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
sapiens]
(736 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap... 1506 0.0
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap... 1470 0.0
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap... 1457 0.0
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap... 1252 0.0
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap... 1172 0.0
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap... 1137 0.0
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap... 1137 0.0
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens] 437 e-122
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi... 428 e-119
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [... 237 3e-62
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [... 237 3e-62
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [... 221 2e-57
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ... 221 2e-57
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [... 221 2e-57
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa... 156 7e-38
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa... 124 4e-28
gi|4505531 oxysterol binding protein [Homo sapiens] 115 1e-25
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [... 109 8e-24
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H... 109 8e-24
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens] 102 2e-21
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [... 100 8e-21
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [... 99 1e-20
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [... 99 1e-20
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [... 90 9e-18
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [... 90 9e-18
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [... 90 9e-18
gi|54792084 pleckstrin homology domain containing, family A (pho... 89 1e-17
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens] 86 1e-16
gi|14165452 alpha 3 type IV collagen binding protein isoform 2 [... 83 1e-15
gi|194294543 alpha 3 type IV collagen binding protein isoform 3 ... 83 1e-15
>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
sapiens]
Length = 736
Score = 1506 bits (3898), Expect = 0.0
Identities = 736/736 (100%), Positives = 736/736 (100%)
Query: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI
Sbjct: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
Query: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120
DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD
Sbjct: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120
Query: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180
KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA
Sbjct: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180
Query: 181 KDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP 240
KDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP
Sbjct: 181 KDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP 240
Query: 241 VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE 300
VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE
Sbjct: 241 VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE 300
Query: 301 FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD 360
FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD
Sbjct: 301 FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD 360
Query: 361 DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI 420
DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI
Sbjct: 361 DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI 420
Query: 421 SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS 480
SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS
Sbjct: 421 SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS 480
Query: 481 EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG 540
EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG
Sbjct: 481 EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG 540
Query: 541 QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG 600
QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG
Sbjct: 541 QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG 600
Query: 601 KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ 660
KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ
Sbjct: 601 KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ 660
Query: 661 NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC 720
NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC
Sbjct: 661 NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC 720
Query: 721 WVYDEPLLKRLGAAKH 736
WVYDEPLLKRLGAAKH
Sbjct: 721 WVYDEPLLKRLGAAKH 736
>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
sapiens]
Length = 723
Score = 1470 bits (3806), Expect = 0.0
Identities = 723/736 (98%), Positives = 723/736 (98%), Gaps = 13/736 (1%)
Query: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI
Sbjct: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
Query: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120
DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD
Sbjct: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120
Query: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180
KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA
Sbjct: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180
Query: 181 KDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP 240
K STINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP
Sbjct: 181 K-------------STINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP 227
Query: 241 VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE 300
VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE
Sbjct: 228 VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE 287
Query: 301 FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD 360
FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD
Sbjct: 288 FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD 347
Query: 361 DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI 420
DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI
Sbjct: 348 DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI 407
Query: 421 SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS 480
SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS
Sbjct: 408 SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS 467
Query: 481 EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG 540
EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG
Sbjct: 468 EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG 527
Query: 541 QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG 600
QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG
Sbjct: 528 QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG 587
Query: 601 KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ 660
KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ
Sbjct: 588 KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ 647
Query: 661 NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC 720
NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC
Sbjct: 648 NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC 707
Query: 721 WVYDEPLLKRLGAAKH 736
WVYDEPLLKRLGAAKH
Sbjct: 708 WVYDEPLLKRLGAAKH 723
>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
sapiens]
Length = 746
Score = 1457 bits (3772), Expect = 0.0
Identities = 723/759 (95%), Positives = 723/759 (95%), Gaps = 36/759 (4%)
Query: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI
Sbjct: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
Query: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQ-------------- 106
DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQ
Sbjct: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGIS 120
Query: 107 ---------GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE 157
GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE
Sbjct: 121 PVLEFSKIIGLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE 180
Query: 158 TLKETTNSMVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMP 217
TLKETTNSMVESIKHCIVLLQIAK STINPVDAIYQPSPLEPVISTMP
Sbjct: 181 TLKETTNSMVESIKHCIVLLQIAK-------------STINPVDAIYQPSPLEPVISTMP 227
Query: 218 SQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVN 277
SQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVN
Sbjct: 228 SQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVN 287
Query: 278 LSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTE 337
LSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTE
Sbjct: 288 LSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTE 347
Query: 338 SLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFI 397
SLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFI
Sbjct: 348 SLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFI 407
Query: 398 LERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPI 457
LERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPI
Sbjct: 408 LERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPI 467
Query: 458 LGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKI 517
LGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKI
Sbjct: 468 LGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKI 527
Query: 518 QFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGEC 577
QFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGEC
Sbjct: 528 QFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGEC 587
Query: 578 NINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGE 637
NINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGE
Sbjct: 588 NINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGE 647
Query: 638 NTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRA 697
NTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRA
Sbjct: 648 NTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRA 707
Query: 698 EARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGAAKH 736
EARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 708 EARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGAAKH 746
>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
sapiens]
Length = 626
Score = 1252 bits (3239), Expect = 0.0
Identities = 617/630 (97%), Positives = 617/630 (97%), Gaps = 13/630 (2%)
Query: 107 GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM 166
GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM
Sbjct: 10 GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM 69
Query: 167 VESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEP 226
VESIKHCIVLLQIAK STINPVDAIYQPSPLEPVISTMPSQTVLPPEP
Sbjct: 70 VESIKHCIVLLQIAK-------------STINPVDAIYQPSPLEPVISTMPSQTVLPPEP 116
Query: 227 VQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEF 286
VQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEF
Sbjct: 117 VQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEF 176
Query: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346
SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG
Sbjct: 177 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 236
Query: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406
TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM
Sbjct: 237 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 296
Query: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHW 466
YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHW
Sbjct: 297 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHW 356
Query: 467 TLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 526
TLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTK
Sbjct: 357 TLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 416
Query: 527 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGY 586
SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGY
Sbjct: 417 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGY 476
Query: 587 SANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKK 646
SANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKK
Sbjct: 477 SANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKK 536
Query: 647 LPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKE 706
LPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKE
Sbjct: 537 LPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKE 596
Query: 707 IQWETRLFHEDGECWVYDEPLLKRLGAAKH 736
IQWETRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 597 IQWETRLFHEDGECWVYDEPLLKRLGAAKH 626
>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
sapiens]
Length = 571
Score = 1172 bits (3032), Expect = 0.0
Identities = 571/571 (100%), Positives = 571/571 (100%)
Query: 166 MVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPE 225
MVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPE
Sbjct: 1 MVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPE 60
Query: 226 PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 285
PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE
Sbjct: 61 PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 120
Query: 286 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 345
FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN
Sbjct: 121 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 180
Query: 346 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 405
GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE
Sbjct: 181 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 240
Query: 406 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 465
MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH
Sbjct: 241 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 300
Query: 466 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 525
WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT
Sbjct: 301 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 360
Query: 526 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 585
KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG
Sbjct: 361 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 420
Query: 586 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 645
YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK
Sbjct: 421 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 480
Query: 646 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 705
KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK
Sbjct: 481 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 540
Query: 706 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 736
EIQWETRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 541 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 571
>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 1137 bits (2940), Expect = 0.0
Identities = 558/571 (97%), Positives = 558/571 (97%), Gaps = 13/571 (2%)
Query: 166 MVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPE 225
MVESIKHCIVLLQIAK STINPVDAIYQPSPLEPVISTMPSQTVLPPE
Sbjct: 1 MVESIKHCIVLLQIAK-------------STINPVDAIYQPSPLEPVISTMPSQTVLPPE 47
Query: 226 PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 285
PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE
Sbjct: 48 PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 107
Query: 286 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 345
FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN
Sbjct: 108 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 167
Query: 346 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 405
GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE
Sbjct: 168 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 227
Query: 406 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 465
MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH
Sbjct: 228 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 287
Query: 466 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 525
WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT
Sbjct: 288 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 347
Query: 526 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 585
KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG
Sbjct: 348 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 407
Query: 586 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 645
YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK
Sbjct: 408 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 467
Query: 646 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 705
KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK
Sbjct: 468 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 527
Query: 706 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 736
EIQWETRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 528 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 558
>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 1137 bits (2940), Expect = 0.0
Identities = 558/571 (97%), Positives = 558/571 (97%), Gaps = 13/571 (2%)
Query: 166 MVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPE 225
MVESIKHCIVLLQIAK STINPVDAIYQPSPLEPVISTMPSQTVLPPE
Sbjct: 1 MVESIKHCIVLLQIAK-------------STINPVDAIYQPSPLEPVISTMPSQTVLPPE 47
Query: 226 PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 285
PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE
Sbjct: 48 PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 107
Query: 286 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 345
FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN
Sbjct: 108 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 167
Query: 346 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 405
GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE
Sbjct: 168 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 227
Query: 406 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 465
MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH
Sbjct: 228 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 287
Query: 466 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 525
WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT
Sbjct: 288 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 347
Query: 526 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 585
KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG
Sbjct: 348 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 407
Query: 586 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 645
YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK
Sbjct: 408 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 467
Query: 646 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 705
KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK
Sbjct: 468 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 527
Query: 706 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 736
EIQWETRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 528 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 558
>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
Length = 747
Score = 437 bits (1123), Expect = e-122
Identities = 214/398 (53%), Positives = 285/398 (71%), Gaps = 20/398 (5%)
Query: 348 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 407
+D ++ D+ D ++DD G+VEE +SVI+HLLSQ++LGMDLT+VVLPTFILE+RSLLEMY
Sbjct: 345 ADDEIEDTCDHKEDDL--GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMY 402
Query: 408 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 467
ADF +HPDLF++I++ +DRM++ V++YL++FH GRKG++AKKPYNPI+GE F C W
Sbjct: 403 ADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWK 462
Query: 468 LPNDTEENTELVSEGPVPWVSKNS----------------VTFVAEQVSHHPPISAFYAE 511
+P +E + + S V+ ++ V FVAEQVSHHPP+S FYAE
Sbjct: 463 MPK-SEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAE 521
Query: 512 CFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWV 571
C +K+ NAH+WTKSKFLGMSIGV +G+G +S L++ E Y + P Y RSILTVPWV
Sbjct: 522 CTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWV 581
Query: 572 ELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYA 631
ELGG+ ++NC+KTGYSA+I FHTKPFYGGK HR+TAE+ C ++GEWN V+
Sbjct: 582 ELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEF 641
Query: 632 KYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRL 691
Y+ GE T +VD KL + KK+VR LE Q+ +ESR LWK+VT +L+ +ID ATE KH L
Sbjct: 642 TYSNGE-TKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTL 700
Query: 692 EERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 729
EERQR E R R E W+T+ F ++G+ WVY +PL K
Sbjct: 701 EERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWK 738
Score = 77.0 bits (188), Expect = 6e-14
Identities = 40/97 (41%), Positives = 58/97 (59%), Gaps = 2/97 (2%)
Query: 7 GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
G L K+TN++ GWQYR+FVL+ AGLL Y+ + ++ RG ++L GAVI DED
Sbjct: 63 GYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVN-EQSRNQKPRGTLQLAGAVISPSDEDSH 121
Query: 67 TFTI-TVDQKTFHFQARDADEREKWIHALEETILRHT 102
TFT+ + + +A DA ER+ W+ L+ HT
Sbjct: 122 TFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHT 158
>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
sapiens]
Length = 764
Score = 428 bits (1100), Expect = e-119
Identities = 210/420 (50%), Positives = 282/420 (67%), Gaps = 14/420 (3%)
Query: 319 SVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHL 378
++L +S+ +P+ + S L S+ + D+ D ++ E G +E+ +S+I+HL
Sbjct: 348 AILPNSAEDEQTSQPEPEPNSGSELV--LSEDEKSDNEDK--EETELGVMEDQRSIILHL 403
Query: 379 LSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYL 438
+SQ++LGMDLTKVVLPTFILE+RSLLEMYADF AHPDL ++I+ P++R++ V++YL
Sbjct: 404 ISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYL 463
Query: 439 SAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPV-----PWVSKNS-- 491
+AFH GRKG++AKKPYNPI+GE F C W +P D + S P P S
Sbjct: 464 TAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPMADDPSKS 523
Query: 492 --VTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDY 549
+ FVAEQVSHHPPIS FY EC K++ N H+WTKSKF+GMS+GV IG+G + L++
Sbjct: 524 YKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEH 583
Query: 550 DEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEI 609
E Y+ T P+ Y RSILT+PWVELGG+ +INC+KTGYSA +IFHTKPFYGGK HR+TAE+
Sbjct: 584 GEEYVFTLPSAYARSILTIPWVELGGKVSINCAKTGYSATVIFHTKPFYGGKVHRVTAEV 643
Query: 610 FSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLW 669
C GEWNG + Y GE V +DT LP+ KK+R LE Q ESR+LW
Sbjct: 644 KHNPTNTIVCKAHGEWNGTLEFTYNNGETKV-IDTTTLPVYPKKIRPLEKQGPMESRNLW 702
Query: 670 KDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 729
++VT L++ DIDAATE K LEE+QR E R+R+ W+ + F ++G+ WVY PL K
Sbjct: 703 REVTRYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYFIQEGDGWVYFNPLWK 762
Score = 70.5 bits (171), Expect = 5e-12
Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 2/98 (2%)
Query: 5 MEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDED 64
+EG LSK+TN+++GWQ R+FVLD+ AG+L Y+ + ++ RG + L GA++ + DE
Sbjct: 77 LEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVN-EQSKHQKPRGVLSLSGAIVSLSDEA 135
Query: 65 DSTFTI-TVDQKTFHFQARDADEREKWIHALEETILRH 101
+ + + + F +A DA E++ W+ L H
Sbjct: 136 PHMLVVYSANGEMFKLRAADAKEKQFWVTQLRACAKYH 173
>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
[Homo sapiens]
Length = 847
Score = 237 bits (604), Expect = 3e-62
Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)
Query: 288 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 347
YS D+ + D+ H S ++ S + T +S P+ E L +
Sbjct: 285 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 340
Query: 348 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 407
S +L ++ + + + EE+KS+I LL QVR GMDL+KVVLPTFILE RS L+
Sbjct: 341 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 397
Query: 408 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 467
+D++ H D + +++P R+ +VVKWYLS F+ KG KKPYNPILGE F+C W
Sbjct: 398 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 455
Query: 468 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 526
P NS TF +AEQVSHHPPISAFY + I K
Sbjct: 456 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 497
Query: 527 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 585
SKF G S+ G+ ++ L+ E Y++T P + + IL +ELGG NI C KTG
Sbjct: 498 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 557
Query: 586 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 641
YSA + F KPF G ++I+ ++ K+ ++EG W+ V T + VF
Sbjct: 558 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 615
Query: 642 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 698
D K+ +I+ V K E+Q ++ES LW+ VT + +D AT+ K+ LEE QR
Sbjct: 616 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 674
Query: 699 ARERKEKEIQWETRLFHED 717
AR+RK K +W +LF D
Sbjct: 675 ARDRKTKNEEWSCKLFELD 693
>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
[Homo sapiens]
Length = 889
Score = 237 bits (604), Expect = 3e-62
Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)
Query: 288 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 347
YS D+ + D+ H S ++ S + T +S P+ E L +
Sbjct: 327 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 382
Query: 348 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 407
S +L ++ + + + EE+KS+I LL QVR GMDL+KVVLPTFILE RS L+
Sbjct: 383 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 439
Query: 408 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 467
+D++ H D + +++P R+ +VVKWYLS F+ KG KKPYNPILGE F+C W
Sbjct: 440 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 497
Query: 468 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 526
P NS TF +AEQVSHHPPISAFY + I K
Sbjct: 498 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 539
Query: 527 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 585
SKF G S+ G+ ++ L+ E Y++T P + + IL +ELGG NI C KTG
Sbjct: 540 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 599
Query: 586 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 641
YSA + F KPF G ++I+ ++ K+ ++EG W+ V T + VF
Sbjct: 600 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 657
Query: 642 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 698
D K+ +I+ V K E+Q ++ES LW+ VT + +D AT+ K+ LEE QR
Sbjct: 658 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 716
Query: 699 ARERKEKEIQWETRLFHED 717
AR+RK K +W +LF D
Sbjct: 717 ARDRKTKNEEWSCKLFELD 735
>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
[Homo sapiens]
Length = 879
Score = 221 bits (563), Expect = 2e-57
Identities = 156/462 (33%), Positives = 234/462 (50%), Gaps = 47/462 (10%)
Query: 280 PNTVPEFSYSS------SEDEFYDADEFHQSGSS-------PKRLIDSSGSASVLTHSSS 326
P T P+ S SS S D D F +GSS K ++ + T S
Sbjct: 261 PGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHS 320
Query: 327 GNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSVIMHLLSQV 382
+ D +E+ + + GT+ + ++ + EA VE E+KS++ LL Q+
Sbjct: 321 RKTESGSDQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSLMWTLLKQL 378
Query: 383 RLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFH 442
R GMDL++VVLPTF+LE RS L +D++ H DL + ++D RM V++WYLS F+
Sbjct: 379 RPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFY 438
Query: 443 AGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHH 502
KG KKPYNPILGE F+C W P T+ T ++AEQVSHH
Sbjct: 439 KKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FYIAEQVSHH 479
Query: 503 PPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYG 562
PP+SAF+ + I KS+F G S+ G+ ++ L+ E Y LT P +
Sbjct: 480 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 539
Query: 563 RSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFC 619
+ IL +ELGG+ I C+K + A + F KPF+GG ++I+ +I S ++
Sbjct: 540 KGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS--GEEVLA 597
Query: 620 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRSLWKDVTFN 675
S+ G W+ ++ K ++ T + ++++R+ LE+Q E ES LW+ VT
Sbjct: 598 SLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRA 657
Query: 676 LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 717
+ D AT+ K LEE QR ARER+E + W+ +LFH D
Sbjct: 658 ISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 699
>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 221 bits (563), Expect = 2e-57
Identities = 156/462 (33%), Positives = 234/462 (50%), Gaps = 47/462 (10%)
Query: 280 PNTVPEFSYSS------SEDEFYDADEFHQSGSS-------PKRLIDSSGSASVLTHSSS 326
P T P+ S SS S D D F +GSS K ++ + T S
Sbjct: 193 PGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHS 252
Query: 327 GNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSVIMHLLSQV 382
+ D +E+ + + GT+ + ++ + EA VE E+KS++ LL Q+
Sbjct: 253 RKTESGSDQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSLMWTLLKQL 310
Query: 383 RLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFH 442
R GMDL++VVLPTF+LE RS L +D++ H DL + ++D RM V++WYLS F+
Sbjct: 311 RPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFY 370
Query: 443 AGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHH 502
KG KKPYNPILGE F+C W P T+ T ++AEQVSHH
Sbjct: 371 KKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FYIAEQVSHH 411
Query: 503 PPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYG 562
PP+SAF+ + I KS+F G S+ G+ ++ L+ E Y LT P +
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471
Query: 563 RSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFC 619
+ IL +ELGG+ I C+K + A + F KPF+GG ++I+ +I S ++
Sbjct: 472 KGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS--GEEVLA 529
Query: 620 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRSLWKDVTFN 675
S+ G W+ ++ K ++ T + ++++R+ LE+Q E ES LW+ VT
Sbjct: 530 SLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRA 589
Query: 676 LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 717
+ D AT+ K LEE QR ARER+E + W+ +LFH D
Sbjct: 590 ISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631
>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 221 bits (563), Expect = 2e-57
Identities = 156/462 (33%), Positives = 234/462 (50%), Gaps = 47/462 (10%)
Query: 280 PNTVPEFSYSS------SEDEFYDADEFHQSGSS-------PKRLIDSSGSASVLTHSSS 326
P T P+ S SS S D D F +GSS K ++ + T S
Sbjct: 193 PGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHS 252
Query: 327 GNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSVIMHLLSQV 382
+ D +E+ + + GT+ + ++ + EA VE E+KS++ LL Q+
Sbjct: 253 RKTESGSDQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSLMWTLLKQL 310
Query: 383 RLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFH 442
R GMDL++VVLPTF+LE RS L +D++ H DL + ++D RM V++WYLS F+
Sbjct: 311 RPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFY 370
Query: 443 AGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHH 502
KG KKPYNPILGE F+C W P T+ T ++AEQVSHH
Sbjct: 371 KKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FYIAEQVSHH 411
Query: 503 PPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYG 562
PP+SAF+ + I KS+F G S+ G+ ++ L+ E Y LT P +
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471
Query: 563 RSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFC 619
+ IL +ELGG+ I C+K + A + F KPF+GG ++I+ +I S ++
Sbjct: 472 KGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS--GEEVLA 529
Query: 620 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRSLWKDVTFN 675
S+ G W+ ++ K ++ T + ++++R+ LE+Q E ES LW+ VT
Sbjct: 530 SLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRA 589
Query: 676 LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 717
+ D AT+ K LEE QR ARER+E + W+ +LFH D
Sbjct: 590 ISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631
>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
sapiens]
Length = 950
Score = 156 bits (394), Expect = 7e-38
Identities = 195/797 (24%), Positives = 303/797 (38%), Gaps = 180/797 (22%)
Query: 6 EGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSK-DKMMRGSRRGCVRLRGAVIGIDDED 64
EGPL K + GW+ W VL++ G+LS+Y + D + R+GC L AV + D
Sbjct: 239 EGPLWKSSRFF-GWRLFWVVLEH--GVLSWYRKQPDAVHNIYRQGCKHLTQAVCTVKSTD 295
Query: 65 DSTFTITVDQKTFH-FQARD---ADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120
F I T H F+ RE W+ A+EE T QD
Sbjct: 296 SCLFFIKCFDDTIHGFRVPKNSLQQSREDWLEAIEEHSAYSTHYCS----------QD-- 343
Query: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180
+LT+ + + LK +K Q+C++ R+ ++ ++ IK C +A
Sbjct: 344 -QLTDEEEEDTVSAADLKKSLEKAQSCQQRLDRE--------ISNFLKMIKEC----DMA 390
Query: 181 KDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP 240
K+ + S + V+ + + S V T E V+ K EQ
Sbjct: 391 KEM---------LPSFLQKVEVVSEASRETCVALTDCLNLFTKQEGVRNFKLEQEQEKNK 441
Query: 241 V-GPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDAD 299
+ L TL S G SPP+S L SEDEFYDA
Sbjct: 442 ILSEALETLATEHHELEQSLVKG-SPPASIL--------------------SEDEFYDA- 479
Query: 300 EFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDR 359
S S +R + + + + G L G+ + + D
Sbjct: 480 ---LSDSESERSLSRLEAVTARSFEEEGEHL---------------GSRKHRMSEEKDCG 521
Query: 360 DDDAEAGSVEEHKSVI---------MHLLSQVR--LGMDLTKVVLPTFILERRSLLEMYA 408
DA + +++H++ + + S +R +GM+L+K+ +P E S L+
Sbjct: 522 GGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLT 581
Query: 409 DFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTL 468
++ H L S DP +RM V + +SA + KP+NP+LGE +
Sbjct: 582 EYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--VASQWERTGKPFNPLLGETY------ 633
Query: 469 PNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSK 528
ELV + ++EQVSHHPPISAF+AE N F+ I+ K K
Sbjct: 634 --------ELVRD-------DLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLK 678
Query: 529 FLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVP-WVELGGECNINCSKTGYS 587
F G S+ G + L+++E Y T P +I+ W+E G I KTG
Sbjct: 679 FWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDK 738
Query: 588 ANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKL 647
+ F +G + H++ I KK C++ G+W +Y+ + + KK
Sbjct: 739 CVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKN 797
Query: 648 PIIKKKVRKLEDQNEYE---------------SRSLWK---------------------- 670
KK +++ E + S LW+
Sbjct: 798 TEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLN 857
Query: 671 -------------DVTFNLKIR-----DIDAATEAKHRLEERQRAEARERKEKEIQWETR 712
D IR +ID A+E K RLEE+QRA + R + E W+TR
Sbjct: 858 EVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTR 917
Query: 713 LFHE------DGECWVY 723
FH+ + W+Y
Sbjct: 918 WFHQGPNPYNGAQDWIY 934
>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
sapiens]
Length = 437
Score = 124 bits (310), Expect = 4e-28
Identities = 106/402 (26%), Positives = 161/402 (40%), Gaps = 86/402 (21%)
Query: 384 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 443
+GM+L+K+ +P E S L+ ++ H L S DP +RM V + +SA
Sbjct: 44 IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--V 101
Query: 444 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 503
+ KP+NP+LGE + ELV + ++EQVSHHP
Sbjct: 102 ASQWERTGKPFNPLLGETY--------------ELVRDDL-------GFRLISEQVSHHP 140
Query: 504 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 563
PISAF+AE N F+ I+ K KF G S+ G + L+++E Y T P
Sbjct: 141 PISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVH 200
Query: 564 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 622
+I+ W+E G I KTG + F +G + H++ I KK C++
Sbjct: 201 NIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALY 259
Query: 623 GEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYE---------------SRS 667
G+W +Y+ + + KK KK +++ E + S
Sbjct: 260 GKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVL 319
Query: 668 LWK-----------------------------------DVTFNLKIR-----DIDAATEA 687
LW+ D IR +ID A+E
Sbjct: 320 LWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEE 379
Query: 688 KHRLEERQRAEARERKEKEIQWETRLFHE------DGECWVY 723
K RLEE+QRA + R + E W+TR FH+ + W+Y
Sbjct: 380 KKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY 421
>gi|4505531 oxysterol binding protein [Homo sapiens]
Length = 807
Score = 115 bits (288), Expect = 1e-25
Identities = 187/782 (23%), Positives = 307/782 (39%), Gaps = 175/782 (22%)
Query: 3 SIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDD 62
S EG L KWTN +KG+Q RWFVL + GLLSYY SK + MR + RG + L A I
Sbjct: 89 SAREGWLFKWTNYIKGYQRRWFVL--SNGLLSYYRSKAE-MRHTCRGTINL--ATANITV 143
Query: 63 EDDSTFTIT-VDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLD-SGFVPSVQDFD 120
ED F I+ +T+H +A ER++W+ ALE + L D SG SV D
Sbjct: 144 EDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEESVSQTD 203
Query: 121 KKLTEADAYLQIL---IEQLKLFDD--------------KLQNCK-EDEQRKKIETLKE- 161
K TE L+ L +E L +D +L++ K E +KI+ + E
Sbjct: 204 K--TELQNTLRTLSSKVEDLSTCNDLIAKHGTALQRSLSELESLKLPAESNEKIKQVNER 261
Query: 162 ------TTNSMVESIKHCIVLLQI--AKDQSNAEKHADGMISTINPVDAI-YQPSPLEPV 212
T+N+M+ + + ++L Q K Q + + D I ++ + Q + LE
Sbjct: 262 ATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLE-- 319
Query: 213 ISTMPSQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTS 272
TVLP TP + GSG S
Sbjct: 320 -RAFRGATVLPAN-----------------------------TPGNVGSGKDQCCSG--- 346
Query: 273 PSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKR 332
+ S E+EF+DA E + L H +G
Sbjct: 347 ----------KGDMSDEDDENEFFDAPEIITMPEN-------------LGHKRTG----- 378
Query: 333 PDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGS-----VEEHKSVIMHLLSQVRLGMD 387
S++S +SD L + + + ++ + + + S+ + + + +G +
Sbjct: 379 --------SNISGASSDISLDEQYKHQLEETKKEKRTRIPYKPNYSLNLWSIMKNCIGKE 430
Query: 388 LTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKG 447
L+K+ +P E S+L+ + + +L + ++ +++ V + +S++
Sbjct: 431 LSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSY--STTV 488
Query: 448 SVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISA 507
KP+NP+LGE F+ + + +N + EQVSHHPP +A
Sbjct: 489 FRTSKPFNPLLGETFE--------------------LDRLEENGYRSLCEQVSHHPPAAA 528
Query: 508 FYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDY--DEHYILTFPNGYGRSI 565
+AE N I SKF G + + + G + C+ + HY +I
Sbjct: 529 HHAESKN-GWTLRQEIKITSKFRGKYLSIMPL--GTIHCIFHATGHHYTWKKVTTTVHNI 585
Query: 566 LTVP-WVELGGECNINCSKTGYSANIIFHTKPFYG-GKKHRITAEIFSPNDKKSFCSIEG 623
+ W++ GE +I KTG N+ F ++ ++T E+ P+ K F ++ G
Sbjct: 586 IVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHF-ALLG 644
Query: 624 EWNGVM---YAKYATGEN-------TVFVDTKKLPIIKKKVRKLEDQNEYESRSL----- 668
W+ M + GEN + ++ + K+ +N Y L
Sbjct: 645 TWDEKMECFKVQPVIGENGGDARQRGHEAEESRVMLWKRNPLPKNAENMYYFSELALTLN 704
Query: 669 -WKDVTFNLKIR-----------DIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHE 716
W+ T R D A K RLEE+QR +R+++E E T E
Sbjct: 705 AWESGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRL-SRKKREAEAMKAT----E 759
Query: 717 DG 718
DG
Sbjct: 760 DG 761
>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
[Homo sapiens]
Length = 480
Score = 109 bits (273), Expect = 8e-24
Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)
Query: 384 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 443
+G++L+K+ +P E S L+ ++ H L S Q P +RM V + +SA
Sbjct: 84 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 141
Query: 444 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 503
+ KP+NP+LGE + EL+ E F++EQVSHHP
Sbjct: 142 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 180
Query: 504 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 563
PISAF++E N F+ I+ K KF G S+ G + L ++E Y T P
Sbjct: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240
Query: 564 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 622
+++ W+E G I +TG+ + F +G + H++ I N KK F I
Sbjct: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 299
Query: 623 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 658
G+W ++ K E++ D+ +P+ ++ V+ +
Sbjct: 300 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 359
Query: 659 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 686
+ S ++ +F + + +++ E
Sbjct: 360 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 419
Query: 687 --AKHRLEERQRAEARERKEKEIQWETRLFH 715
K RLEE+QR RER ++E +W+TR F+
Sbjct: 420 SQEKERLEEKQREARRERAKEEAEWQTRWFY 450
>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
sapiens]
Length = 468
Score = 109 bits (273), Expect = 8e-24
Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)
Query: 384 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 443
+G++L+K+ +P E S L+ ++ H L S Q P +RM V + +SA
Sbjct: 72 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 129
Query: 444 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 503
+ KP+NP+LGE + EL+ E F++EQVSHHP
Sbjct: 130 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 168
Query: 504 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 563
PISAF++E N F+ I+ K KF G S+ G + L ++E Y T P
Sbjct: 169 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 228
Query: 564 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 622
+++ W+E G I +TG+ + F +G + H++ I N KK F I
Sbjct: 229 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 287
Query: 623 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 658
G+W ++ K E++ D+ +P+ ++ V+ +
Sbjct: 288 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 347
Query: 659 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 686
+ S ++ +F + + +++ E
Sbjct: 348 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 407
Query: 687 --AKHRLEERQRAEARERKEKEIQWETRLFH 715
K RLEE+QR RER ++E +W+TR F+
Sbjct: 408 SQEKERLEEKQREARRERAKEEAEWQTRWFY 438
>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
Length = 916
Score = 102 bits (253), Expect = 2e-21
Identities = 176/750 (23%), Positives = 282/750 (37%), Gaps = 129/750 (17%)
Query: 6 EGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDD 65
EG L KWTN +KG+Q RWFVL GLLSYY ++ +M + RG + L A ID ED
Sbjct: 186 EGWLLKWTNYLKGYQRRWFVL--GNGLLSYYRNQGEMAH-TCRGTINLSTA--HIDTEDS 240
Query: 66 STFTITVDQKTFHFQARDADEREKWIHALEETILR--HTLQLQGLDSGFVPSVQDFDKKL 123
+T +++H +A +R++WI ALE + + DSG D D+
Sbjct: 241 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSG------DDDEAT 294
Query: 124 TEAD-AYLQILIEQLKLFDDKLQNCKE---------DEQRKKIETLKETTNSMVESIKHC 173
T AD + L ++ L L D L C + +++ LK + S E +K
Sbjct: 295 TPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSES-GEKLKVV 353
Query: 174 IVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSE 233
+ + SNA MI+ + + I + Q L E Q E
Sbjct: 354 NERATLFRITSNA------MINACRDFLELAE-------IHSRKWQRALQYEQEQRVHLE 400
Query: 234 QRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSED 293
+ L H P + S S LT E S +
Sbjct: 401 ETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGSLLTPKG----------EDSEEDEDT 450
Query: 294 EFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDT-TESLN-SSLSNGTSDAD 351
E++DA E DS+ +V+T + + T T S++ SS N A
Sbjct: 451 EYFDAME------------DSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGAS 498
Query: 352 LFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFF 411
L + + + S+ + + + +G +L+++ +P E S+L+ +
Sbjct: 499 LVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDL 558
Query: 412 AHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPND 471
+ L ++M V + +S++ KP+NP+LGE F+ D
Sbjct: 559 EYHHLLDKAVHCTSSVEQMCLVAAFSVSSY--STTVHRIAKPFNPMLGETFEL------D 610
Query: 472 TEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT------ 525
++ L S + EQVSHHPP +A Y F+ H W+
Sbjct: 611 RLDDMGLRS--------------LCEQVSHHPPSAAHYV--------FSKHGWSLWQEIT 648
Query: 526 -KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVP-WVELGGECNINCSK 583
SKF G I + +G + HY+ +I+ W++ G+ I K
Sbjct: 649 ISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHK 708
Query: 584 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEW------NGVMYAKYAT-- 635
T + F ++ + R + S + K+ + G W + VM++ ++
Sbjct: 709 TNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPS 768
Query: 636 --GENTVFVDTKKLPIIKKKVRKLEDQ-------------NEYE------SRSLWKDVTF 674
G+ T ++ KK E+ NE+E L D
Sbjct: 769 SDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRL 828
Query: 675 NLKIRDIDAATEAKHRLEERQRAEARERKE 704
K R +A TE K RLEE+QR R R E
Sbjct: 829 MEKGRWDEANTE-KQRLEEKQRLSRRRRLE 857
>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
[Homo sapiens]
Length = 820
Score = 99.8 bits (247), Expect = 8e-21
Identities = 181/808 (22%), Positives = 306/808 (37%), Gaps = 140/808 (17%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSVK-KSSKCIDL 117
Query: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADAYL 130
++ +H + + + ++W+ L H + Q + F V F T D+
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKLRH----HRMYRQNEIAMFPHEVNHFFSGSTITDSSS 173
Query: 131 QIL--IEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM----VESIKHCIVLLQIAKDQS 184
+ I K QN + ET + E ++ C +KD +
Sbjct: 174 GVFDSISSRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKC------SKDLA 227
Query: 185 NAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLP-PEPVQLCKSEQRPSSLPVGP 243
+ + M + +D +++ P I+ + Q P PV+L S S+L G
Sbjct: 228 HCHAYLVEMSQLLQSMDVLHRTYSA-PAINAI--QVPKPFSGPVRLHSSNPNLSTLDFGE 284
Query: 244 VLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQ 303
+ T S S L +H + F+ S+E E
Sbjct: 285 ------EKNYSDGSETSSEFSKMQEDLCHIAH-KVYFTLRSAFNIMSAEREKLKQLMEQD 337
Query: 304 SGSSP-------KRLIDSSGSAS---VLTHSSSGNSLKRPDTTESLN------------S 341
+ SSP K + S S L H S S R T+SL+ S
Sbjct: 338 ASSSPSAQVIGLKNALSSENSRDENRALVHQLSNES--RLSITDSLSEFFDAQEVLLSPS 395
Query: 342 SLSNGTSDADLF--DSHDDRDDDAEAGSVEEHKSVIMHLLSQVR---------------- 383
S N SD D + D D+ D + ++ + + +L R
Sbjct: 396 SSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPS 455
Query: 384 -------------LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRM 430
+G DL+KV +P + E + L+ + + +L + P +RM
Sbjct: 456 SSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERM 515
Query: 431 VQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVS 488
V V + +SA+ + R GS KP+NP+LGE ++C + E
Sbjct: 516 VYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC--------------IRED------ 552
Query: 489 KNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLD 548
F +EQVSHHPPISA +AE ++ F + K+KF G S+ + IG V+
Sbjct: 553 -KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 609
Query: 549 YDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCSKTGYSANIIFHTKPFYGGKKHRIT 606
+ +H+ +IL+ W+E GE I N + F ++ H I
Sbjct: 610 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 669
Query: 607 AEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE------DQ 660
+F K+ + G+W+ +Y + V+ + P+ K + +
Sbjct: 670 GTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW---RANPMPKGYEQYYSFTQFALEL 725
Query: 661 NEYE--SRSLW--KDVTFN-----LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWET 711
NE + S+SL D F L+ +++ A K R+E+ QR R +E ++ +
Sbjct: 726 NEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQP 785
Query: 712 RLFHE-DGECWVYDEPLL---KRLGAAK 735
R F + D + WV + L K LG +K
Sbjct: 786 RFFRKSDDDSWVSNGTYLELRKDLGFSK 813
>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
[Homo sapiens]
Length = 938
Score = 99.4 bits (246), Expect = 1e-20
Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)
Query: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346
S S S EF+DA E S SS + ++S S ++ S S ++++ + NG
Sbjct: 491 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 548
Query: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406
F + R A + + ++L +G DL+KV +P + E + L+
Sbjct: 549 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 605
Query: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464
+ + +L S+ DP +RMV V + +S + + R GS KP+NP+LGE ++C
Sbjct: 606 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 662
Query: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524
+ E F +EQVSHHPPISA C +K F I
Sbjct: 663 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 699
Query: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 583
K+KF G S+ + +G V Y ++Y+ +IL+ W+E GE I +K
Sbjct: 700 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 759
Query: 584 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 641
+ + K Y + + K+ + G+W+ +Y A ++
Sbjct: 760 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 819
Query: 642 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 683
++ +L P++K + + + + R L + +++A
Sbjct: 820 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 871
Query: 684 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 725
A K R+EE QR+ R +E ++ + F + E WV ++
Sbjct: 872 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 918
Score = 34.7 bits (78), Expect = 0.33
Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+FVLD G+L Y + + +G G + + +V+ I + +
Sbjct: 77 KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 131
Query: 71 TVDQKTFHFQARDADEREKWIHAL 94
++ +H + + D + W+ L
Sbjct: 132 DTEEHIYHLKVKSQDWFDAWVSKL 155
>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
[Homo sapiens]
Length = 934
Score = 99.4 bits (246), Expect = 1e-20
Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)
Query: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346
S S S EF+DA E S SS + ++S S ++ S S ++++ + NG
Sbjct: 487 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 544
Query: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406
F + R A + + ++L +G DL+KV +P + E + L+
Sbjct: 545 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 601
Query: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464
+ + +L S+ DP +RMV V + +S + + R GS KP+NP+LGE ++C
Sbjct: 602 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 658
Query: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524
+ E F +EQVSHHPPISA C +K F I
Sbjct: 659 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 695
Query: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 583
K+KF G S+ + +G V Y ++Y+ +IL+ W+E GE I +K
Sbjct: 696 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 755
Query: 584 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 641
+ + K Y + + K+ + G+W+ +Y A ++
Sbjct: 756 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 815
Query: 642 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 683
++ +L P++K + + + + R L + +++A
Sbjct: 816 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 867
Query: 684 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 725
A K R+EE QR+ R +E ++ + F + E WV ++
Sbjct: 868 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 914
Score = 34.7 bits (78), Expect = 0.33
Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+FVLD G+L Y + + +G G + + +V+ I + +
Sbjct: 98 KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 152
Query: 71 TVDQKTFHFQARDADEREKWIHAL 94
++ +H + + D + W+ L
Sbjct: 153 DTEEHIYHLKVKSQDWFDAWVSKL 176
>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
[Homo sapiens]
Length = 851
Score = 89.7 bits (221), Expect = 9e-18
Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)
Query: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346
S + S EF+DA E S SS + I S S ++L + + L++
Sbjct: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462
Query: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406
D R ++ + + + +G DL+KV +P + E + L+
Sbjct: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522
Query: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464
+ + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C
Sbjct: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579
Query: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524
+ E F +EQVSHHPPISA +AE ++ F +
Sbjct: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616
Query: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 582
K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N
Sbjct: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676
Query: 583 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 642
+ F ++ H I +F K+ + G+W+ +Y + V+
Sbjct: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734
Query: 643 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 687
+ P+ K + + NE + S+SL D F L+ +++ A
Sbjct: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792
Query: 688 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 735
K R+E+ QR R +E ++ + R F + D + WV + L K LG +K
Sbjct: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844
Score = 38.9 bits (89), Expect = 0.017
Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
Query: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128
++ +H + + + ++W+ L H + Q + F V F T D+
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171
>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
[Homo sapiens]
Length = 856
Score = 89.7 bits (221), Expect = 9e-18
Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)
Query: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346
S + S EF+DA E S SS + I S S ++L + + L++
Sbjct: 412 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 467
Query: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406
D R ++ + + + +G DL+KV +P + E + L+
Sbjct: 468 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 527
Query: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464
+ + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C
Sbjct: 528 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 584
Query: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524
+ E F +EQVSHHPPISA +AE ++ F +
Sbjct: 585 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 621
Query: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 582
K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N
Sbjct: 622 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 681
Query: 583 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 642
+ F ++ H I +F K+ + G+W+ +Y + V+
Sbjct: 682 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 739
Query: 643 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 687
+ P+ K + + NE + S+SL D F L+ +++ A
Sbjct: 740 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 797
Query: 688 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 735
K R+E+ QR R +E ++ + R F + D + WV + L K LG +K
Sbjct: 798 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 849
Score = 38.9 bits (89), Expect = 0.017
Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
Query: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128
++ +H + + + ++W+ L H + Q + F V F T D+
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171
>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
[Homo sapiens]
Length = 887
Score = 89.7 bits (221), Expect = 9e-18
Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)
Query: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346
S + S EF+DA E S SS + I S S ++L + + L++
Sbjct: 443 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 498
Query: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406
D R ++ + + + +G DL+KV +P + E + L+
Sbjct: 499 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 558
Query: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464
+ + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C
Sbjct: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 615
Query: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524
+ E F +EQVSHHPPISA +AE ++ F +
Sbjct: 616 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 652
Query: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 582
K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N
Sbjct: 653 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 712
Query: 583 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 642
+ F ++ H I +F K+ + G+W+ +Y + V+
Sbjct: 713 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 770
Query: 643 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 687
+ P+ K + + NE + S+SL D F L+ +++ A
Sbjct: 771 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 828
Query: 688 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 735
K R+E+ QR R +E ++ + R F + D + WV + L K LG +K
Sbjct: 829 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 880
Score = 38.9 bits (89), Expect = 0.017
Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
Query: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128
++ +H + + + ++W+ L H + Q + F V F T D+
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171
>gi|54792084 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 3 [Homo
sapiens]
Length = 300
Score = 89.0 bits (219), Expect = 1e-17
Identities = 81/312 (25%), Positives = 140/312 (44%), Gaps = 42/312 (13%)
Query: 5 MEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDED 64
MEG L KWTN + GWQ RWFVLD G+LSYY S+D + +GS +G +++ I + D
Sbjct: 1 MEGVLYKWTNYLTGWQPRWFVLD--NGILSYYDSQDDVCKGS-KGSIKMAVCEIKVHSAD 57
Query: 65 DSTFTITV-DQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKL 123
++ + + ++ F+ +A +A ER++W+ AL + T + + + K+
Sbjct: 58 NTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTKKEKEISETSESLKTKM 117
Query: 124 TEADAYLQILIEQLKLF------DDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLL 177
+E Y +L++Q+ D+ + + + L T N+ + +++ C+ +
Sbjct: 118 SELRLYCDLLMQQVHTIQEFVHHDENHSSPSAENMNEASSLLSATCNTFITTLEECVKIA 177
Query: 178 QIA-KDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRP 236
K + H D ++S ++ PSP++ M ++V P C SE+
Sbjct: 178 NAKFKPEMFQLHHPDPLVSPVS-------PSPVQ-----MMKRSVSHPGS---CSSERSS 222
Query: 237 SSL--PVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHV-------NLSPNTVPEFS 287
S+ PV L L + T + T S P P H +L+ T+PE S
Sbjct: 223 HSIKEPVS-TLHRLSQRRRRTYSDTDSCSDIPLEDPDRPVHCSKNTLNGDLASATIPEES 281
Query: 288 ------YSSSED 293
S SED
Sbjct: 282 RLMAKKQSESED 293
>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
Length = 842
Score = 85.9 bits (211), Expect = 1e-16
Identities = 87/347 (25%), Positives = 145/347 (41%), Gaps = 43/347 (12%)
Query: 384 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 443
+G DL+KV +P + E + L+ + + L S DP +RMV + + +SA+ +
Sbjct: 487 IGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERMVYIAAFAVSAYSS 546
Query: 444 G--RKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSH 501
R G KP+NP+LGE ++C E P F++EQVSH
Sbjct: 547 TYHRAGC---KPFNPVLGETYEC----------------ERP-----DRGFRFISEQVSH 582
Query: 502 HPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGY 561
HPPISA +AE ++ F + K+KF G S+ + +G VS + +H+
Sbjct: 583 HPPISACHAE--SENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSC 640
Query: 562 GRSILT-VPWVELGGECNI-NCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFC 619
++L+ W+E GE I N + I F ++ H + + S +
Sbjct: 641 IHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLS-RSGRVLH 699
Query: 620 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKK------VRKLEDQNEYESRSLWKDVT 673
+ G+W+ +Y G ++ P ++ +L + RSL T
Sbjct: 700 RLFGKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDT 759
Query: 674 ------FNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLF 714
L+ +I AA K R+E+ QR + +E I + R F
Sbjct: 760 RLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFF 806
Score = 45.1 bits (105), Expect = 2e-04
Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+FVL+ G+L Y T++ + +G G + +R +V+ I ++ +
Sbjct: 59 KWP--LKGWHKRYFVLE--DGILHYATTRQDITKGKLHGSIDVRLSVMSI-NKKAQRIDL 113
Query: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQL 105
+ +H + + D + W+ L L H L +
Sbjct: 114 DTEDNIYHLKIKSQDLFQSWVAQLRAHRLAHRLDM 148
>gi|14165452 alpha 3 type IV collagen binding protein isoform 2
[Homo sapiens]
Length = 598
Score = 82.8 bits (203), Expect = 1e-15
Identities = 62/175 (35%), Positives = 84/175 (48%), Gaps = 28/175 (16%)
Query: 7 GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
G LSKWTN + GWQ RW VL NA LSYY S+D+ G R G + L AVI D D+
Sbjct: 28 GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCR-GSICLSKAVITPHDFDEC 84
Query: 67 TFTITVDQKTFHFQARDADEREKWIHALE----------ETILRHTLQLQGLDSG----F 112
F I+V+ ++ +A+D D R++WI A+E E+ LR + L SG
Sbjct: 85 RFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYS 144
Query: 113 VPSVQDFDK------KLTEADAYLQILIEQLKLFDDKLQNC-----KEDEQRKKI 156
S F K KL E + + IL Q+ C K++ QR K+
Sbjct: 145 ATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKV 199
>gi|194294543 alpha 3 type IV collagen binding protein isoform 3
[Homo sapiens]
Length = 752
Score = 82.8 bits (203), Expect = 1e-15
Identities = 62/175 (35%), Positives = 84/175 (48%), Gaps = 28/175 (16%)
Query: 7 GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
G LSKWTN + GWQ RW VL NA LSYY S+D+ G R G + L AVI D D+
Sbjct: 156 GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCR-GSICLSKAVITPHDFDEC 212
Query: 67 TFTITVDQKTFHFQARDADEREKWIHALE----------ETILRHTLQLQGLDSG----F 112
F I+V+ ++ +A+D D R++WI A+E E+ LR + L SG
Sbjct: 213 RFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYS 272
Query: 113 VPSVQDFDK------KLTEADAYLQILIEQLKLFDDKLQNC-----KEDEQRKKI 156
S F K KL E + + IL Q+ C K++ QR K+
Sbjct: 273 ATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKV 327
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,491,995
Number of Sequences: 37866
Number of extensions: 1453551
Number of successful extensions: 8438
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 265
Number of HSP's that attempted gapping in prelim test: 7337
Number of HSP's gapped (non-prelim): 1154
length of query: 736
length of database: 18,247,518
effective HSP length: 110
effective length of query: 626
effective length of database: 14,082,258
effective search space: 8815493508
effective search space used: 8815493508
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.