Guide to the Human Genome
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Search of human proteins with 20070331

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
sapiens]
         (736 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap...  1506   0.0  
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap...  1470   0.0  
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap...  1457   0.0  
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap...  1252   0.0  
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap...  1172   0.0  
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap...  1137   0.0  
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap...  1137   0.0  
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]          437   e-122
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi...   428   e-119
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [...   237   3e-62
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [...   237   3e-62
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [...   221   2e-57
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ...   221   2e-57
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [...   221   2e-57
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa...   156   7e-38
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa...   124   4e-28
gi|4505531 oxysterol binding protein [Homo sapiens]                   115   1e-25
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [...   109   8e-24
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H...   109   8e-24
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]      102   2e-21
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [...   100   8e-21
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [...    99   1e-20
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [...    99   1e-20
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [...    90   9e-18
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [...    90   9e-18
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [...    90   9e-18
gi|54792084 pleckstrin homology domain containing, family A (pho...    89   1e-17
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]    86   1e-16
gi|14165452 alpha 3 type IV collagen binding protein isoform 2 [...    83   1e-15
gi|194294543 alpha 3 type IV collagen binding protein isoform 3 ...    83   1e-15

>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
           sapiens]
          Length = 736

 Score = 1506 bits (3898), Expect = 0.0
 Identities = 736/736 (100%), Positives = 736/736 (100%)

Query: 1   MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
           MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI
Sbjct: 1   MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60

Query: 61  DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120
           DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD
Sbjct: 61  DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120

Query: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180
           KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA
Sbjct: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180

Query: 181 KDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP 240
           KDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP
Sbjct: 181 KDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP 240

Query: 241 VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE 300
           VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE
Sbjct: 241 VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE 300

Query: 301 FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD 360
           FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD
Sbjct: 301 FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD 360

Query: 361 DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI 420
           DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI
Sbjct: 361 DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI 420

Query: 421 SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS 480
           SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS
Sbjct: 421 SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS 480

Query: 481 EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG 540
           EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG
Sbjct: 481 EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG 540

Query: 541 QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG 600
           QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG
Sbjct: 541 QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG 600

Query: 601 KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ 660
           KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ
Sbjct: 601 KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ 660

Query: 661 NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC 720
           NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC
Sbjct: 661 NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC 720

Query: 721 WVYDEPLLKRLGAAKH 736
           WVYDEPLLKRLGAAKH
Sbjct: 721 WVYDEPLLKRLGAAKH 736


>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
           sapiens]
          Length = 723

 Score = 1470 bits (3806), Expect = 0.0
 Identities = 723/736 (98%), Positives = 723/736 (98%), Gaps = 13/736 (1%)

Query: 1   MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
           MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI
Sbjct: 1   MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60

Query: 61  DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120
           DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD
Sbjct: 61  DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120

Query: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180
           KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA
Sbjct: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180

Query: 181 KDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP 240
           K             STINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP
Sbjct: 181 K-------------STINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP 227

Query: 241 VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE 300
           VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE
Sbjct: 228 VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE 287

Query: 301 FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD 360
           FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD
Sbjct: 288 FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD 347

Query: 361 DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI 420
           DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI
Sbjct: 348 DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI 407

Query: 421 SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS 480
           SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS
Sbjct: 408 SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS 467

Query: 481 EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG 540
           EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG
Sbjct: 468 EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG 527

Query: 541 QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG 600
           QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG
Sbjct: 528 QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG 587

Query: 601 KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ 660
           KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ
Sbjct: 588 KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ 647

Query: 661 NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC 720
           NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC
Sbjct: 648 NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC 707

Query: 721 WVYDEPLLKRLGAAKH 736
           WVYDEPLLKRLGAAKH
Sbjct: 708 WVYDEPLLKRLGAAKH 723


>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
           sapiens]
          Length = 746

 Score = 1457 bits (3772), Expect = 0.0
 Identities = 723/759 (95%), Positives = 723/759 (95%), Gaps = 36/759 (4%)

Query: 1   MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
           MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI
Sbjct: 1   MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60

Query: 61  DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQ-------------- 106
           DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQ              
Sbjct: 61  DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGIS 120

Query: 107 ---------GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE 157
                    GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE
Sbjct: 121 PVLEFSKIIGLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE 180

Query: 158 TLKETTNSMVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMP 217
           TLKETTNSMVESIKHCIVLLQIAK             STINPVDAIYQPSPLEPVISTMP
Sbjct: 181 TLKETTNSMVESIKHCIVLLQIAK-------------STINPVDAIYQPSPLEPVISTMP 227

Query: 218 SQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVN 277
           SQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVN
Sbjct: 228 SQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVN 287

Query: 278 LSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTE 337
           LSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTE
Sbjct: 288 LSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTE 347

Query: 338 SLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFI 397
           SLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFI
Sbjct: 348 SLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFI 407

Query: 398 LERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPI 457
           LERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPI
Sbjct: 408 LERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPI 467

Query: 458 LGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKI 517
           LGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKI
Sbjct: 468 LGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKI 527

Query: 518 QFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGEC 577
           QFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGEC
Sbjct: 528 QFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGEC 587

Query: 578 NINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGE 637
           NINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGE
Sbjct: 588 NINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGE 647

Query: 638 NTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRA 697
           NTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRA
Sbjct: 648 NTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRA 707

Query: 698 EARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGAAKH 736
           EARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 708 EARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGAAKH 746


>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
           sapiens]
          Length = 626

 Score = 1252 bits (3239), Expect = 0.0
 Identities = 617/630 (97%), Positives = 617/630 (97%), Gaps = 13/630 (2%)

Query: 107 GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM 166
           GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM
Sbjct: 10  GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM 69

Query: 167 VESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEP 226
           VESIKHCIVLLQIAK             STINPVDAIYQPSPLEPVISTMPSQTVLPPEP
Sbjct: 70  VESIKHCIVLLQIAK-------------STINPVDAIYQPSPLEPVISTMPSQTVLPPEP 116

Query: 227 VQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEF 286
           VQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEF
Sbjct: 117 VQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEF 176

Query: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346
           SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG
Sbjct: 177 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 236

Query: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406
           TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM
Sbjct: 237 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 296

Query: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHW 466
           YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHW
Sbjct: 297 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHW 356

Query: 467 TLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 526
           TLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTK
Sbjct: 357 TLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 416

Query: 527 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGY 586
           SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGY
Sbjct: 417 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGY 476

Query: 587 SANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKK 646
           SANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKK
Sbjct: 477 SANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKK 536

Query: 647 LPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKE 706
           LPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKE
Sbjct: 537 LPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKE 596

Query: 707 IQWETRLFHEDGECWVYDEPLLKRLGAAKH 736
           IQWETRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 597 IQWETRLFHEDGECWVYDEPLLKRLGAAKH 626


>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
           sapiens]
          Length = 571

 Score = 1172 bits (3032), Expect = 0.0
 Identities = 571/571 (100%), Positives = 571/571 (100%)

Query: 166 MVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPE 225
           MVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPE
Sbjct: 1   MVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPE 60

Query: 226 PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 285
           PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE
Sbjct: 61  PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 120

Query: 286 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 345
           FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN
Sbjct: 121 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 180

Query: 346 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 405
           GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE
Sbjct: 181 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 240

Query: 406 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 465
           MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH
Sbjct: 241 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 300

Query: 466 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 525
           WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT
Sbjct: 301 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 360

Query: 526 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 585
           KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG
Sbjct: 361 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 420

Query: 586 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 645
           YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK
Sbjct: 421 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 480

Query: 646 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 705
           KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK
Sbjct: 481 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 540

Query: 706 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 736
           EIQWETRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 541 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 571


>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score = 1137 bits (2940), Expect = 0.0
 Identities = 558/571 (97%), Positives = 558/571 (97%), Gaps = 13/571 (2%)

Query: 166 MVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPE 225
           MVESIKHCIVLLQIAK             STINPVDAIYQPSPLEPVISTMPSQTVLPPE
Sbjct: 1   MVESIKHCIVLLQIAK-------------STINPVDAIYQPSPLEPVISTMPSQTVLPPE 47

Query: 226 PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 285
           PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE
Sbjct: 48  PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 107

Query: 286 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 345
           FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN
Sbjct: 108 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 167

Query: 346 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 405
           GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE
Sbjct: 168 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 227

Query: 406 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 465
           MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH
Sbjct: 228 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 287

Query: 466 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 525
           WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT
Sbjct: 288 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 347

Query: 526 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 585
           KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG
Sbjct: 348 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 407

Query: 586 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 645
           YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK
Sbjct: 408 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 467

Query: 646 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 705
           KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK
Sbjct: 468 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 527

Query: 706 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 736
           EIQWETRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 528 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 558


>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score = 1137 bits (2940), Expect = 0.0
 Identities = 558/571 (97%), Positives = 558/571 (97%), Gaps = 13/571 (2%)

Query: 166 MVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPE 225
           MVESIKHCIVLLQIAK             STINPVDAIYQPSPLEPVISTMPSQTVLPPE
Sbjct: 1   MVESIKHCIVLLQIAK-------------STINPVDAIYQPSPLEPVISTMPSQTVLPPE 47

Query: 226 PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 285
           PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE
Sbjct: 48  PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 107

Query: 286 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 345
           FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN
Sbjct: 108 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 167

Query: 346 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 405
           GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE
Sbjct: 168 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 227

Query: 406 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 465
           MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH
Sbjct: 228 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 287

Query: 466 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 525
           WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT
Sbjct: 288 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 347

Query: 526 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 585
           KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG
Sbjct: 348 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 407

Query: 586 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 645
           YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK
Sbjct: 408 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 467

Query: 646 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 705
           KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK
Sbjct: 468 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 527

Query: 706 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 736
           EIQWETRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 528 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 558


>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
          Length = 747

 Score =  437 bits (1123), Expect = e-122
 Identities = 214/398 (53%), Positives = 285/398 (71%), Gaps = 20/398 (5%)

Query: 348 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 407
           +D ++ D+ D ++DD   G+VEE +SVI+HLLSQ++LGMDLT+VVLPTFILE+RSLLEMY
Sbjct: 345 ADDEIEDTCDHKEDDL--GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMY 402

Query: 408 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 467
           ADF +HPDLF++I++    +DRM++ V++YL++FH GRKG++AKKPYNPI+GE F C W 
Sbjct: 403 ADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWK 462

Query: 468 LPNDTEENTELVSEGPVPWVSKNS----------------VTFVAEQVSHHPPISAFYAE 511
           +P  +E  + + S      V+ ++                V FVAEQVSHHPP+S FYAE
Sbjct: 463 MPK-SEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAE 521

Query: 512 CFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWV 571
           C  +K+  NAH+WTKSKFLGMSIGV  +G+G +S L++ E Y  + P  Y RSILTVPWV
Sbjct: 522 CTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWV 581

Query: 572 ELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYA 631
           ELGG+ ++NC+KTGYSA+I FHTKPFYGGK HR+TAE+         C ++GEWN V+  
Sbjct: 582 ELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEF 641

Query: 632 KYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRL 691
            Y+ GE T +VD  KL + KK+VR LE Q+ +ESR LWK+VT +L+  +ID ATE KH L
Sbjct: 642 TYSNGE-TKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTL 700

Query: 692 EERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 729
           EERQR E R R E    W+T+ F ++G+ WVY +PL K
Sbjct: 701 EERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWK 738



 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 40/97 (41%), Positives = 58/97 (59%), Gaps = 2/97 (2%)

Query: 7   GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
           G L K+TN++ GWQYR+FVL+  AGLL Y+ + ++      RG ++L GAVI   DED  
Sbjct: 63  GYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVN-EQSRNQKPRGTLQLAGAVISPSDEDSH 121

Query: 67  TFTI-TVDQKTFHFQARDADEREKWIHALEETILRHT 102
           TFT+     + +  +A DA ER+ W+  L+     HT
Sbjct: 122 TFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHT 158


>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
           sapiens]
          Length = 764

 Score =  428 bits (1100), Expect = e-119
 Identities = 210/420 (50%), Positives = 282/420 (67%), Gaps = 14/420 (3%)

Query: 319 SVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHL 378
           ++L +S+      +P+   +  S L    S+ +  D+ D   ++ E G +E+ +S+I+HL
Sbjct: 348 AILPNSAEDEQTSQPEPEPNSGSELV--LSEDEKSDNEDK--EETELGVMEDQRSIILHL 403

Query: 379 LSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYL 438
           +SQ++LGMDLTKVVLPTFILE+RSLLEMYADF AHPDL ++I+    P++R++  V++YL
Sbjct: 404 ISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYL 463

Query: 439 SAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPV-----PWVSKNS-- 491
           +AFH GRKG++AKKPYNPI+GE F C W +P D  +     S  P      P     S  
Sbjct: 464 TAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPMADDPSKS 523

Query: 492 --VTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDY 549
             + FVAEQVSHHPPIS FY EC  K++  N H+WTKSKF+GMS+GV  IG+G +  L++
Sbjct: 524 YKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEH 583

Query: 550 DEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEI 609
            E Y+ T P+ Y RSILT+PWVELGG+ +INC+KTGYSA +IFHTKPFYGGK HR+TAE+
Sbjct: 584 GEEYVFTLPSAYARSILTIPWVELGGKVSINCAKTGYSATVIFHTKPFYGGKVHRVTAEV 643

Query: 610 FSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLW 669
                    C   GEWNG +   Y  GE  V +DT  LP+  KK+R LE Q   ESR+LW
Sbjct: 644 KHNPTNTIVCKAHGEWNGTLEFTYNNGETKV-IDTTTLPVYPKKIRPLEKQGPMESRNLW 702

Query: 670 KDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 729
           ++VT  L++ DIDAATE K  LEE+QR E R+R+     W+ + F ++G+ WVY  PL K
Sbjct: 703 REVTRYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYFIQEGDGWVYFNPLWK 762



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 2/98 (2%)

Query: 5   MEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDED 64
           +EG LSK+TN+++GWQ R+FVLD+ AG+L Y+ + ++      RG + L GA++ + DE 
Sbjct: 77  LEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVN-EQSKHQKPRGVLSLSGAIVSLSDEA 135

Query: 65  DSTFTI-TVDQKTFHFQARDADEREKWIHALEETILRH 101
                + + + + F  +A DA E++ W+  L      H
Sbjct: 136 PHMLVVYSANGEMFKLRAADAKEKQFWVTQLRACAKYH 173


>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
           [Homo sapiens]
          Length = 847

 Score =  237 bits (604), Expect = 3e-62
 Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)

Query: 288 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 347
           YS   D+  + D+ H    S   ++  S  +   T     +S   P+  E L  +     
Sbjct: 285 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 340

Query: 348 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 407
           S  +L ++ +    +  +   EE+KS+I  LL QVR GMDL+KVVLPTFILE RS L+  
Sbjct: 341 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 397

Query: 408 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 467
           +D++ H D     + +++P  R+ +VVKWYLS F+   KG   KKPYNPILGE F+C W 
Sbjct: 398 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 455

Query: 468 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 526
            P                    NS TF +AEQVSHHPPISAFY          +  I  K
Sbjct: 456 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 497

Query: 527 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 585
           SKF G S+     G+  ++ L+  E Y++T P  + + IL     +ELGG  NI C KTG
Sbjct: 498 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 557

Query: 586 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 641
           YSA + F  KPF G     ++I+ ++     K+   ++EG W+  V      T  + VF 
Sbjct: 558 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 615

Query: 642 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 698
               D K+  +I+  V K E+Q ++ES  LW+ VT  +  +D   AT+ K+ LEE QR  
Sbjct: 616 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 674

Query: 699 ARERKEKEIQWETRLFHED 717
           AR+RK K  +W  +LF  D
Sbjct: 675 ARDRKTKNEEWSCKLFELD 693


>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
           [Homo sapiens]
          Length = 889

 Score =  237 bits (604), Expect = 3e-62
 Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)

Query: 288 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 347
           YS   D+  + D+ H    S   ++  S  +   T     +S   P+  E L  +     
Sbjct: 327 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 382

Query: 348 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 407
           S  +L ++ +    +  +   EE+KS+I  LL QVR GMDL+KVVLPTFILE RS L+  
Sbjct: 383 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 439

Query: 408 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 467
           +D++ H D     + +++P  R+ +VVKWYLS F+   KG   KKPYNPILGE F+C W 
Sbjct: 440 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 497

Query: 468 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 526
            P                    NS TF +AEQVSHHPPISAFY          +  I  K
Sbjct: 498 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 539

Query: 527 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 585
           SKF G S+     G+  ++ L+  E Y++T P  + + IL     +ELGG  NI C KTG
Sbjct: 540 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 599

Query: 586 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 641
           YSA + F  KPF G     ++I+ ++     K+   ++EG W+  V      T  + VF 
Sbjct: 600 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 657

Query: 642 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 698
               D K+  +I+  V K E+Q ++ES  LW+ VT  +  +D   AT+ K+ LEE QR  
Sbjct: 658 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 716

Query: 699 ARERKEKEIQWETRLFHED 717
           AR+RK K  +W  +LF  D
Sbjct: 717 ARDRKTKNEEWSCKLFELD 735


>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
           [Homo sapiens]
          Length = 879

 Score =  221 bits (563), Expect = 2e-57
 Identities = 156/462 (33%), Positives = 234/462 (50%), Gaps = 47/462 (10%)

Query: 280 PNTVPEFSYSS------SEDEFYDADEFHQSGSS-------PKRLIDSSGSASVLTHSSS 326
           P T P+ S SS      S     D D F  +GSS        K   ++   +   T   S
Sbjct: 261 PGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHS 320

Query: 327 GNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSVIMHLLSQV 382
             +    D +E+  + +  GT+  +     ++  +  EA  VE    E+KS++  LL Q+
Sbjct: 321 RKTESGSDQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSLMWTLLKQL 378

Query: 383 RLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFH 442
           R GMDL++VVLPTF+LE RS L   +D++ H DL    + ++D   RM  V++WYLS F+
Sbjct: 379 RPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFY 438

Query: 443 AGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHH 502
              KG   KKPYNPILGE F+C W  P  T+  T                 ++AEQVSHH
Sbjct: 439 KKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FYIAEQVSHH 479

Query: 503 PPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYG 562
           PP+SAF+          +  I  KS+F G S+     G+  ++ L+  E Y LT P  + 
Sbjct: 480 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 539

Query: 563 RSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFC 619
           + IL     +ELGG+  I C+K  + A + F  KPF+GG    ++I+ +I S   ++   
Sbjct: 540 KGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS--GEEVLA 597

Query: 620 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRSLWKDVTFN 675
           S+ G W+  ++ K     ++    T    + ++++R+    LE+Q E ES  LW+ VT  
Sbjct: 598 SLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRA 657

Query: 676 LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 717
           +   D   AT+ K  LEE QR  ARER+E  + W+ +LFH D
Sbjct: 658 ISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 699


>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  221 bits (563), Expect = 2e-57
 Identities = 156/462 (33%), Positives = 234/462 (50%), Gaps = 47/462 (10%)

Query: 280 PNTVPEFSYSS------SEDEFYDADEFHQSGSS-------PKRLIDSSGSASVLTHSSS 326
           P T P+ S SS      S     D D F  +GSS        K   ++   +   T   S
Sbjct: 193 PGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHS 252

Query: 327 GNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSVIMHLLSQV 382
             +    D +E+  + +  GT+  +     ++  +  EA  VE    E+KS++  LL Q+
Sbjct: 253 RKTESGSDQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSLMWTLLKQL 310

Query: 383 RLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFH 442
           R GMDL++VVLPTF+LE RS L   +D++ H DL    + ++D   RM  V++WYLS F+
Sbjct: 311 RPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFY 370

Query: 443 AGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHH 502
              KG   KKPYNPILGE F+C W  P  T+  T                 ++AEQVSHH
Sbjct: 371 KKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FYIAEQVSHH 411

Query: 503 PPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYG 562
           PP+SAF+          +  I  KS+F G S+     G+  ++ L+  E Y LT P  + 
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471

Query: 563 RSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFC 619
           + IL     +ELGG+  I C+K  + A + F  KPF+GG    ++I+ +I S   ++   
Sbjct: 472 KGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS--GEEVLA 529

Query: 620 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRSLWKDVTFN 675
           S+ G W+  ++ K     ++    T    + ++++R+    LE+Q E ES  LW+ VT  
Sbjct: 530 SLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRA 589

Query: 676 LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 717
           +   D   AT+ K  LEE QR  ARER+E  + W+ +LFH D
Sbjct: 590 ISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631


>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  221 bits (563), Expect = 2e-57
 Identities = 156/462 (33%), Positives = 234/462 (50%), Gaps = 47/462 (10%)

Query: 280 PNTVPEFSYSS------SEDEFYDADEFHQSGSS-------PKRLIDSSGSASVLTHSSS 326
           P T P+ S SS      S     D D F  +GSS        K   ++   +   T   S
Sbjct: 193 PGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHS 252

Query: 327 GNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSVIMHLLSQV 382
             +    D +E+  + +  GT+  +     ++  +  EA  VE    E+KS++  LL Q+
Sbjct: 253 RKTESGSDQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSLMWTLLKQL 310

Query: 383 RLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFH 442
           R GMDL++VVLPTF+LE RS L   +D++ H DL    + ++D   RM  V++WYLS F+
Sbjct: 311 RPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFY 370

Query: 443 AGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHH 502
              KG   KKPYNPILGE F+C W  P  T+  T                 ++AEQVSHH
Sbjct: 371 KKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FYIAEQVSHH 411

Query: 503 PPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYG 562
           PP+SAF+          +  I  KS+F G S+     G+  ++ L+  E Y LT P  + 
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471

Query: 563 RSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFC 619
           + IL     +ELGG+  I C+K  + A + F  KPF+GG    ++I+ +I S   ++   
Sbjct: 472 KGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS--GEEVLA 529

Query: 620 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRSLWKDVTFN 675
           S+ G W+  ++ K     ++    T    + ++++R+    LE+Q E ES  LW+ VT  
Sbjct: 530 SLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRA 589

Query: 676 LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 717
           +   D   AT+ K  LEE QR  ARER+E  + W+ +LFH D
Sbjct: 590 ISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631


>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
           sapiens]
          Length = 950

 Score =  156 bits (394), Expect = 7e-38
 Identities = 195/797 (24%), Positives = 303/797 (38%), Gaps = 180/797 (22%)

Query: 6   EGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSK-DKMMRGSRRGCVRLRGAVIGIDDED 64
           EGPL K +    GW+  W VL++  G+LS+Y  + D +    R+GC  L  AV  +   D
Sbjct: 239 EGPLWKSSRFF-GWRLFWVVLEH--GVLSWYRKQPDAVHNIYRQGCKHLTQAVCTVKSTD 295

Query: 65  DSTFTITVDQKTFH-FQARD---ADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120
              F I     T H F+         RE W+ A+EE     T              QD  
Sbjct: 296 SCLFFIKCFDDTIHGFRVPKNSLQQSREDWLEAIEEHSAYSTHYCS----------QD-- 343

Query: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180
            +LT+ +    +    LK   +K Q+C++   R+         ++ ++ IK C     +A
Sbjct: 344 -QLTDEEEEDTVSAADLKKSLEKAQSCQQRLDRE--------ISNFLKMIKEC----DMA 390

Query: 181 KDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP 240
           K+          + S +  V+ + + S    V  T         E V+  K EQ      
Sbjct: 391 KEM---------LPSFLQKVEVVSEASRETCVALTDCLNLFTKQEGVRNFKLEQEQEKNK 441

Query: 241 V-GPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDAD 299
           +    L TL         S   G SPP+S L                    SEDEFYDA 
Sbjct: 442 ILSEALETLATEHHELEQSLVKG-SPPASIL--------------------SEDEFYDA- 479

Query: 300 EFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDR 359
               S S  +R +    + +  +    G  L               G+    + +  D  
Sbjct: 480 ---LSDSESERSLSRLEAVTARSFEEEGEHL---------------GSRKHRMSEEKDCG 521

Query: 360 DDDAEAGSVEEHKSVI---------MHLLSQVR--LGMDLTKVVLPTFILERRSLLEMYA 408
             DA +  +++H++ +           + S +R  +GM+L+K+ +P    E  S L+   
Sbjct: 522 GGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLT 581

Query: 409 DFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTL 468
           ++  H  L    S   DP +RM  V  + +SA     +     KP+NP+LGE +      
Sbjct: 582 EYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--VASQWERTGKPFNPLLGETY------ 633

Query: 469 PNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSK 528
                   ELV +             ++EQVSHHPPISAF+AE  N    F+  I+ K K
Sbjct: 634 --------ELVRD-------DLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLK 678

Query: 529 FLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVP-WVELGGECNINCSKTGYS 587
           F G S+     G   +  L+++E Y  T P     +I+    W+E  G   I   KTG  
Sbjct: 679 FWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDK 738

Query: 588 ANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKL 647
             + F     +G + H++   I     KK  C++ G+W   +Y+      +    + KK 
Sbjct: 739 CVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKN 797

Query: 648 PIIKKKVRKLEDQNEYE---------------SRSLWK---------------------- 670
              KK  +++    E +               S  LW+                      
Sbjct: 798 TEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLN 857

Query: 671 -------------DVTFNLKIR-----DIDAATEAKHRLEERQRAEARERKEKEIQWETR 712
                        D      IR     +ID A+E K RLEE+QRA  + R + E  W+TR
Sbjct: 858 EVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTR 917

Query: 713 LFHE------DGECWVY 723
            FH+        + W+Y
Sbjct: 918 WFHQGPNPYNGAQDWIY 934


>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
           sapiens]
          Length = 437

 Score =  124 bits (310), Expect = 4e-28
 Identities = 106/402 (26%), Positives = 161/402 (40%), Gaps = 86/402 (21%)

Query: 384 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 443
           +GM+L+K+ +P    E  S L+   ++  H  L    S   DP +RM  V  + +SA   
Sbjct: 44  IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--V 101

Query: 444 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 503
             +     KP+NP+LGE +              ELV +             ++EQVSHHP
Sbjct: 102 ASQWERTGKPFNPLLGETY--------------ELVRDDL-------GFRLISEQVSHHP 140

Query: 504 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 563
           PISAF+AE  N    F+  I+ K KF G S+     G   +  L+++E Y  T P     
Sbjct: 141 PISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVH 200

Query: 564 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 622
           +I+    W+E  G   I   KTG    + F     +G + H++   I     KK  C++ 
Sbjct: 201 NIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALY 259

Query: 623 GEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYE---------------SRS 667
           G+W   +Y+      +    + KK    KK  +++    E +               S  
Sbjct: 260 GKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVL 319

Query: 668 LWK-----------------------------------DVTFNLKIR-----DIDAATEA 687
           LW+                                   D      IR     +ID A+E 
Sbjct: 320 LWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEE 379

Query: 688 KHRLEERQRAEARERKEKEIQWETRLFHE------DGECWVY 723
           K RLEE+QRA  + R + E  W+TR FH+        + W+Y
Sbjct: 380 KKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY 421


>gi|4505531 oxysterol binding protein [Homo sapiens]
          Length = 807

 Score =  115 bits (288), Expect = 1e-25
 Identities = 187/782 (23%), Positives = 307/782 (39%), Gaps = 175/782 (22%)

Query: 3   SIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDD 62
           S  EG L KWTN +KG+Q RWFVL  + GLLSYY SK + MR + RG + L  A   I  
Sbjct: 89  SAREGWLFKWTNYIKGYQRRWFVL--SNGLLSYYRSKAE-MRHTCRGTINL--ATANITV 143

Query: 63  EDDSTFTIT-VDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLD-SGFVPSVQDFD 120
           ED   F I+    +T+H +A    ER++W+ ALE    +    L   D SG   SV   D
Sbjct: 144 EDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEESVSQTD 203

Query: 121 KKLTEADAYLQIL---IEQLKLFDD--------------KLQNCK-EDEQRKKIETLKE- 161
           K  TE    L+ L   +E L   +D              +L++ K   E  +KI+ + E 
Sbjct: 204 K--TELQNTLRTLSSKVEDLSTCNDLIAKHGTALQRSLSELESLKLPAESNEKIKQVNER 261

Query: 162 ------TTNSMVESIKHCIVLLQI--AKDQSNAEKHADGMISTINPVDAI-YQPSPLEPV 212
                 T+N+M+ + +  ++L Q    K Q + +   D  I     ++ +  Q + LE  
Sbjct: 262 ATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLE-- 319

Query: 213 ISTMPSQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTS 272
                  TVLP                               TP + GSG     S    
Sbjct: 320 -RAFRGATVLPAN-----------------------------TPGNVGSGKDQCCSG--- 346

Query: 273 PSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKR 332
                       + S    E+EF+DA E      +             L H  +G     
Sbjct: 347 ----------KGDMSDEDDENEFFDAPEIITMPEN-------------LGHKRTG----- 378

Query: 333 PDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGS-----VEEHKSVIMHLLSQVRLGMD 387
                   S++S  +SD  L + +  + ++ +         + + S+ +  + +  +G +
Sbjct: 379 --------SNISGASSDISLDEQYKHQLEETKKEKRTRIPYKPNYSLNLWSIMKNCIGKE 430

Query: 388 LTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKG 447
           L+K+ +P    E  S+L+   +   + +L    +  ++  +++  V  + +S++      
Sbjct: 431 LSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSY--STTV 488

Query: 448 SVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISA 507
               KP+NP+LGE F+                    +  + +N    + EQVSHHPP +A
Sbjct: 489 FRTSKPFNPLLGETFE--------------------LDRLEENGYRSLCEQVSHHPPAAA 528

Query: 508 FYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDY--DEHYILTFPNGYGRSI 565
            +AE  N        I   SKF G  + +  +  G + C+ +    HY          +I
Sbjct: 529 HHAESKN-GWTLRQEIKITSKFRGKYLSIMPL--GTIHCIFHATGHHYTWKKVTTTVHNI 585

Query: 566 LTVP-WVELGGECNINCSKTGYSANIIFHTKPFYG-GKKHRITAEIFSPNDKKSFCSIEG 623
           +    W++  GE +I   KTG   N+ F    ++      ++T E+  P+ K  F ++ G
Sbjct: 586 IVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHF-ALLG 644

Query: 624 EWNGVM---YAKYATGEN-------TVFVDTKKLPIIKKKVRKLEDQNEYESRSL----- 668
            W+  M     +   GEN           +  ++ + K+       +N Y    L     
Sbjct: 645 TWDEKMECFKVQPVIGENGGDARQRGHEAEESRVMLWKRNPLPKNAENMYYFSELALTLN 704

Query: 669 -WKDVTFNLKIR-----------DIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHE 716
            W+  T     R             D A   K RLEE+QR  +R+++E E    T    E
Sbjct: 705 AWESGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRL-SRKKREAEAMKAT----E 759

Query: 717 DG 718
           DG
Sbjct: 760 DG 761


>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
           [Homo sapiens]
          Length = 480

 Score =  109 bits (273), Expect = 8e-24
 Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)

Query: 384 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 443
           +G++L+K+ +P    E  S L+   ++  H  L    S Q  P +RM  V  + +SA   
Sbjct: 84  VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 141

Query: 444 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 503
             +     KP+NP+LGE +              EL+ E            F++EQVSHHP
Sbjct: 142 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 180

Query: 504 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 563
           PISAF++E  N    F+  I+ K KF G S+     G   +  L ++E Y  T P     
Sbjct: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240

Query: 564 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 622
           +++    W+E  G   I   +TG+   + F     +G + H++   I   N KK F  I 
Sbjct: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 299

Query: 623 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 658
           G+W   ++                     K    E++   D+     +P+ ++ V+ +  
Sbjct: 300 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 359

Query: 659 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 686
                  +     S  ++   +F + + +++   E                         
Sbjct: 360 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 419

Query: 687 --AKHRLEERQRAEARERKEKEIQWETRLFH 715
              K RLEE+QR   RER ++E +W+TR F+
Sbjct: 420 SQEKERLEEKQREARRERAKEEAEWQTRWFY 450


>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
           sapiens]
          Length = 468

 Score =  109 bits (273), Expect = 8e-24
 Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)

Query: 384 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 443
           +G++L+K+ +P    E  S L+   ++  H  L    S Q  P +RM  V  + +SA   
Sbjct: 72  VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 129

Query: 444 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 503
             +     KP+NP+LGE +              EL+ E            F++EQVSHHP
Sbjct: 130 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 168

Query: 504 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 563
           PISAF++E  N    F+  I+ K KF G S+     G   +  L ++E Y  T P     
Sbjct: 169 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 228

Query: 564 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 622
           +++    W+E  G   I   +TG+   + F     +G + H++   I   N KK F  I 
Sbjct: 229 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 287

Query: 623 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 658
           G+W   ++                     K    E++   D+     +P+ ++ V+ +  
Sbjct: 288 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 347

Query: 659 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 686
                  +     S  ++   +F + + +++   E                         
Sbjct: 348 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 407

Query: 687 --AKHRLEERQRAEARERKEKEIQWETRLFH 715
              K RLEE+QR   RER ++E +W+TR F+
Sbjct: 408 SQEKERLEEKQREARRERAKEEAEWQTRWFY 438


>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
          Length = 916

 Score =  102 bits (253), Expect = 2e-21
 Identities = 176/750 (23%), Positives = 282/750 (37%), Gaps = 129/750 (17%)

Query: 6   EGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDD 65
           EG L KWTN +KG+Q RWFVL    GLLSYY ++ +M   + RG + L  A   ID ED 
Sbjct: 186 EGWLLKWTNYLKGYQRRWFVL--GNGLLSYYRNQGEMAH-TCRGTINLSTA--HIDTEDS 240

Query: 66  STFTITVDQKTFHFQARDADEREKWIHALEETILR--HTLQLQGLDSGFVPSVQDFDKKL 123
               +T   +++H +A    +R++WI ALE    +    +     DSG      D D+  
Sbjct: 241 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSG------DDDEAT 294

Query: 124 TEAD-AYLQILIEQLKLFDDKLQNCKE---------DEQRKKIETLKETTNSMVESIKHC 173
           T AD + L   ++ L L  D L  C +              +++ LK  + S  E +K  
Sbjct: 295 TPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSES-GEKLKVV 353

Query: 174 IVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSE 233
                + +  SNA      MI+       + +       I +   Q  L  E  Q    E
Sbjct: 354 NERATLFRITSNA------MINACRDFLELAE-------IHSRKWQRALQYEQEQRVHLE 400

Query: 234 QRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSED 293
           +    L           H  P   +  S      S LT             E S    + 
Sbjct: 401 ETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGSLLTPKG----------EDSEEDEDT 450

Query: 294 EFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDT-TESLN-SSLSNGTSDAD 351
           E++DA E            DS+   +V+T +   +      T T S++ SS  N    A 
Sbjct: 451 EYFDAME------------DSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGAS 498

Query: 352 LFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFF 411
           L      +         + + S+ +  + +  +G +L+++ +P    E  S+L+   +  
Sbjct: 499 LVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDL 558

Query: 412 AHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPND 471
            +  L           ++M  V  + +S++          KP+NP+LGE F+       D
Sbjct: 559 EYHHLLDKAVHCTSSVEQMCLVAAFSVSSY--STTVHRIAKPFNPMLGETFEL------D 610

Query: 472 TEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT------ 525
             ++  L S              + EQVSHHPP +A Y         F+ H W+      
Sbjct: 611 RLDDMGLRS--------------LCEQVSHHPPSAAHYV--------FSKHGWSLWQEIT 648

Query: 526 -KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVP-WVELGGECNINCSK 583
             SKF G  I +  +G   +       HY+         +I+    W++  G+  I   K
Sbjct: 649 ISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHK 708

Query: 584 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEW------NGVMYAKYAT-- 635
           T     + F    ++  +  R    + S +  K+   + G W      + VM++  ++  
Sbjct: 709 TNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPS 768

Query: 636 --GENTVFVDTKKLPIIKKKVRKLEDQ-------------NEYE------SRSLWKDVTF 674
             G+      T    ++ KK    E+              NE+E         L  D   
Sbjct: 769 SDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRL 828

Query: 675 NLKIRDIDAATEAKHRLEERQRAEARERKE 704
             K R  +A TE K RLEE+QR   R R E
Sbjct: 829 MEKGRWDEANTE-KQRLEEKQRLSRRRRLE 857


>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
           [Homo sapiens]
          Length = 820

 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 181/808 (22%), Positives = 306/808 (37%), Gaps = 140/808 (17%)

Query: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
           KW   +KGW  R+F LD   G+L Y  S+  + R    GC+ +  +V+ +  +      +
Sbjct: 63  KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSVK-KSSKCIDL 117

Query: 71  TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADAYL 130
             ++  +H + +  +  ++W+  L      H +  Q   + F   V  F    T  D+  
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKLRH----HRMYRQNEIAMFPHEVNHFFSGSTITDSSS 173

Query: 131 QIL--IEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM----VESIKHCIVLLQIAKDQS 184
            +   I   K      QN  +           ET   +     E ++ C      +KD +
Sbjct: 174 GVFDSISSRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKC------SKDLA 227

Query: 185 NAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLP-PEPVQLCKSEQRPSSLPVGP 243
           +   +   M   +  +D +++     P I+ +  Q   P   PV+L  S    S+L  G 
Sbjct: 228 HCHAYLVEMSQLLQSMDVLHRTYSA-PAINAI--QVPKPFSGPVRLHSSNPNLSTLDFGE 284

Query: 244 VLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQ 303
                        + T S  S     L   +H  +       F+  S+E E         
Sbjct: 285 ------EKNYSDGSETSSEFSKMQEDLCHIAH-KVYFTLRSAFNIMSAEREKLKQLMEQD 337

Query: 304 SGSSP-------KRLIDSSGSAS---VLTHSSSGNSLKRPDTTESLN------------S 341
           + SSP       K  + S  S      L H  S  S  R   T+SL+            S
Sbjct: 338 ASSSPSAQVIGLKNALSSENSRDENRALVHQLSNES--RLSITDSLSEFFDAQEVLLSPS 395

Query: 342 SLSNGTSDADLF--DSHDDRDDDAEAGSVEEHKSVIMHLLSQVR---------------- 383
           S  N  SD D +  D  D+   D  +  ++  +  +  +L   R                
Sbjct: 396 SSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPS 455

Query: 384 -------------LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRM 430
                        +G DL+KV +P  + E  + L+   +   + +L    +    P +RM
Sbjct: 456 SSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERM 515

Query: 431 VQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVS 488
           V V  + +SA+ +   R GS   KP+NP+LGE ++C              + E       
Sbjct: 516 VYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC--------------IRED------ 552

Query: 489 KNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLD 548
                F +EQVSHHPPISA +AE  ++   F   +  K+KF G S+ +  IG   V+   
Sbjct: 553 -KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 609

Query: 549 YDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCSKTGYSANIIFHTKPFYGGKKHRIT 606
           + +H+          +IL+   W+E  GE  I N         + F    ++    H I 
Sbjct: 610 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 669

Query: 607 AEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE------DQ 660
             +F     K+   + G+W+  +Y    +    V+   +  P+ K   +         + 
Sbjct: 670 GTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW---RANPMPKGYEQYYSFTQFALEL 725

Query: 661 NEYE--SRSLW--KDVTFN-----LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWET 711
           NE +  S+SL    D  F      L+  +++ A   K R+E+ QR   R  +E  ++ + 
Sbjct: 726 NEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQP 785

Query: 712 RLFHE-DGECWVYDEPLL---KRLGAAK 735
           R F + D + WV +   L   K LG +K
Sbjct: 786 RFFRKSDDDSWVSNGTYLELRKDLGFSK 813


>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
           [Homo sapiens]
          Length = 938

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 491 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 548

Query: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 549 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 605

Query: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 606 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 662

Query: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 663 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 699

Query: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 583
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 700 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 759

Query: 584 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 641
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 760 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 819

Query: 642 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 683
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 820 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 871

Query: 684 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 725
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 872 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 918



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)

Query: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
           KW   +KGW  R+FVLD   G+L Y  +   + +G   G + +  +V+ I  +      +
Sbjct: 77  KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 131

Query: 71  TVDQKTFHFQARDADEREKWIHAL 94
             ++  +H + +  D  + W+  L
Sbjct: 132 DTEEHIYHLKVKSQDWFDAWVSKL 155


>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
           [Homo sapiens]
          Length = 934

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 487 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 544

Query: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 545 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 601

Query: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 602 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 658

Query: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 659 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 695

Query: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 583
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 696 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 755

Query: 584 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 641
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 756 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 815

Query: 642 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 683
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 816 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 867

Query: 684 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 725
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 868 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 914



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)

Query: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
           KW   +KGW  R+FVLD   G+L Y  +   + +G   G + +  +V+ I  +      +
Sbjct: 98  KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 152

Query: 71  TVDQKTFHFQARDADEREKWIHAL 94
             ++  +H + +  D  + W+  L
Sbjct: 153 DTEEHIYHLKVKSQDWFDAWVSKL 176


>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
           [Homo sapiens]
          Length = 851

 Score = 89.7 bits (221), Expect = 9e-18
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462

Query: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522

Query: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579

Query: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616

Query: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 582
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676

Query: 583 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 642
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734

Query: 643 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 687
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792

Query: 688 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 735
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
           KW   +KGW  R+F LD   G+L Y  S+  + R    GC+ +  +V+ +  +      +
Sbjct: 63  KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117

Query: 71  TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128
             ++  +H + +  +  ++W+  L      H +  Q   + F   V  F    T  D+
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171


>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
           [Homo sapiens]
          Length = 856

 Score = 89.7 bits (221), Expect = 9e-18
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 412 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 467

Query: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 468 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 527

Query: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 528 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 584

Query: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 585 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 621

Query: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 582
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 622 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 681

Query: 583 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 642
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 682 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 739

Query: 643 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 687
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 740 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 797

Query: 688 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 735
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 798 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 849



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
           KW   +KGW  R+F LD   G+L Y  S+  + R    GC+ +  +V+ +  +      +
Sbjct: 63  KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117

Query: 71  TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128
             ++  +H + +  +  ++W+  L      H +  Q   + F   V  F    T  D+
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171


>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
           [Homo sapiens]
          Length = 887

 Score = 89.7 bits (221), Expect = 9e-18
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 443 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 498

Query: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 499 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 558

Query: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 615

Query: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 616 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 652

Query: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 582
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 653 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 712

Query: 583 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 642
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 713 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 770

Query: 643 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 687
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 771 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 828

Query: 688 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 735
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 829 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 880



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
           KW   +KGW  R+F LD   G+L Y  S+  + R    GC+ +  +V+ +  +      +
Sbjct: 63  KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117

Query: 71  TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128
             ++  +H + +  +  ++W+  L      H +  Q   + F   V  F    T  D+
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171


>gi|54792084 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 3 [Homo
           sapiens]
          Length = 300

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 81/312 (25%), Positives = 140/312 (44%), Gaps = 42/312 (13%)

Query: 5   MEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDED 64
           MEG L KWTN + GWQ RWFVLD   G+LSYY S+D + +GS +G +++    I +   D
Sbjct: 1   MEGVLYKWTNYLTGWQPRWFVLD--NGILSYYDSQDDVCKGS-KGSIKMAVCEIKVHSAD 57

Query: 65  DSTFTITV-DQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKL 123
           ++   + +  ++ F+ +A +A ER++W+ AL  +    T      +     + +    K+
Sbjct: 58  NTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTKKEKEISETSESLKTKM 117

Query: 124 TEADAYLQILIEQLKLF------DDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLL 177
           +E   Y  +L++Q+         D+   +   +   +    L  T N+ + +++ C+ + 
Sbjct: 118 SELRLYCDLLMQQVHTIQEFVHHDENHSSPSAENMNEASSLLSATCNTFITTLEECVKIA 177

Query: 178 QIA-KDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRP 236
               K +     H D ++S ++       PSP++     M  ++V  P     C SE+  
Sbjct: 178 NAKFKPEMFQLHHPDPLVSPVS-------PSPVQ-----MMKRSVSHPGS---CSSERSS 222

Query: 237 SSL--PVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHV-------NLSPNTVPEFS 287
            S+  PV   L  L   +  T + T S    P      P H        +L+  T+PE S
Sbjct: 223 HSIKEPVS-TLHRLSQRRRRTYSDTDSCSDIPLEDPDRPVHCSKNTLNGDLASATIPEES 281

Query: 288 ------YSSSED 293
                  S SED
Sbjct: 282 RLMAKKQSESED 293


>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
          Length = 842

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 87/347 (25%), Positives = 145/347 (41%), Gaps = 43/347 (12%)

Query: 384 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 443
           +G DL+KV +P  + E  + L+   +   +  L    S   DP +RMV +  + +SA+ +
Sbjct: 487 IGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERMVYIAAFAVSAYSS 546

Query: 444 G--RKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSH 501
              R G    KP+NP+LGE ++C                E P          F++EQVSH
Sbjct: 547 TYHRAGC---KPFNPVLGETYEC----------------ERP-----DRGFRFISEQVSH 582

Query: 502 HPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGY 561
           HPPISA +AE  ++   F   +  K+KF G S+ +  +G   VS   + +H+        
Sbjct: 583 HPPISACHAE--SENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSC 640

Query: 562 GRSILT-VPWVELGGECNI-NCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFC 619
             ++L+   W+E  GE  I N   +     I F    ++    H +   + S    +   
Sbjct: 641 IHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLS-RSGRVLH 699

Query: 620 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKK------VRKLEDQNEYESRSLWKDVT 673
            + G+W+  +Y     G   ++      P  ++         +L +      RSL    T
Sbjct: 700 RLFGKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDT 759

Query: 674 ------FNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLF 714
                   L+  +I AA   K R+E+ QR   +  +E  I  + R F
Sbjct: 760 RLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFF 806



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 5/95 (5%)

Query: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
           KW   +KGW  R+FVL+   G+L Y T++  + +G   G + +R +V+ I ++      +
Sbjct: 59  KWP--LKGWHKRYFVLE--DGILHYATTRQDITKGKLHGSIDVRLSVMSI-NKKAQRIDL 113

Query: 71  TVDQKTFHFQARDADEREKWIHALEETILRHTLQL 105
             +   +H + +  D  + W+  L    L H L +
Sbjct: 114 DTEDNIYHLKIKSQDLFQSWVAQLRAHRLAHRLDM 148


>gi|14165452 alpha 3 type IV collagen binding protein isoform 2
           [Homo sapiens]
          Length = 598

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 62/175 (35%), Positives = 84/175 (48%), Gaps = 28/175 (16%)

Query: 7   GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
           G LSKWTN + GWQ RW VL  NA  LSYY S+D+   G R G + L  AVI   D D+ 
Sbjct: 28  GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCR-GSICLSKAVITPHDFDEC 84

Query: 67  TFTITVDQKTFHFQARDADEREKWIHALE----------ETILRHTLQLQGLDSG----F 112
            F I+V+   ++ +A+D D R++WI A+E          E+ LR    +  L SG     
Sbjct: 85  RFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYS 144

Query: 113 VPSVQDFDK------KLTEADAYLQILIEQLKLFDDKLQNC-----KEDEQRKKI 156
             S   F K      KL E + +  IL  Q+         C     K++ QR K+
Sbjct: 145 ATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKV 199


>gi|194294543 alpha 3 type IV collagen binding protein isoform 3
           [Homo sapiens]
          Length = 752

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 62/175 (35%), Positives = 84/175 (48%), Gaps = 28/175 (16%)

Query: 7   GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
           G LSKWTN + GWQ RW VL  NA  LSYY S+D+   G R G + L  AVI   D D+ 
Sbjct: 156 GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCR-GSICLSKAVITPHDFDEC 212

Query: 67  TFTITVDQKTFHFQARDADEREKWIHALE----------ETILRHTLQLQGLDSG----F 112
            F I+V+   ++ +A+D D R++WI A+E          E+ LR    +  L SG     
Sbjct: 213 RFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYS 272

Query: 113 VPSVQDFDK------KLTEADAYLQILIEQLKLFDDKLQNC-----KEDEQRKKI 156
             S   F K      KL E + +  IL  Q+         C     K++ QR K+
Sbjct: 273 ATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKV 327


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,491,995
Number of Sequences: 37866
Number of extensions: 1453551
Number of successful extensions: 8438
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 265
Number of HSP's that attempted gapping in prelim test: 7337
Number of HSP's gapped (non-prelim): 1154
length of query: 736
length of database: 18,247,518
effective HSP length: 110
effective length of query: 626
effective length of database: 14,082,258
effective search space: 8815493508
effective search space used: 8815493508
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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