Search of human proteins with 19923838

Search of human proteins with 19923838

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923838 solute carrier family 13 (sodium/sulfate
symporters), member 1 [Homo sapiens]
         (595 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923838 solute carrier family 13 (sodium/sulfate symporters)...  1198   0.0  
gi|31795546 solute carrier family 13 (sodium/sulfate symporters)...   585   e-167
gi|4506979 solute carrier family 13, member 2 isoform b [Homo sa...   518   e-147
gi|225637549 solute carrier family 13, member 2 isoform a [Homo ...   495   e-140
gi|29171306 solute carrier family 13, member 5 isoform a [Homo s...   491   e-139
gi|31377715 solute carrier family 13 member 3 isoform a [Homo sa...   463   e-130
gi|225637552 solute carrier family 13, member 2 isoform c [Homo ...   453   e-127
gi|58761541 solute carrier family 13 member 3 isoform b [Homo sa...   437   e-122
gi|219802232 solute carrier family 13, member 5 isoform b [Homo ...   403   e-112
gi|157266326 oculocutaneous albinism II [Homo sapiens]                 52   1e-06
gi|167736355 mucin 4 isoform a [Homo sapiens]                          33   0.74 
gi|38348366 suprabasin [Homo sapiens]                                  32   2.2  
gi|239749916 PREDICTED: hypothetical protein XP_002347212 [Homo ...    31   2.8  
gi|239744219 PREDICTED: hypothetical protein XP_002343076 [Homo ...    31   2.8  
gi|102467481 sphingomyelin phosphodiesterase 4 isoform 2 [Homo s...    30   6.3  
gi|102467484 sphingomyelin phosphodiesterase 4 isoform 1 [Homo s...    30   6.3  

>gi|19923838 solute carrier family 13 (sodium/sulfate symporters),
           member 1 [Homo sapiens]
          Length = 595

 Score = 1198 bits (3100), Expect = 0.0
 Identities = 595/595 (100%), Positives = 595/595 (100%)

Query: 1   MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL 60
           MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL
Sbjct: 1   MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL 60

Query: 61  LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP 120
           LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP
Sbjct: 61  LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP 120

Query: 121 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG 180
           AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG
Sbjct: 121 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG 180

Query: 181 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLT 240
           LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLT
Sbjct: 181 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLT 240

Query: 241 CLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSW 300
           CLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSW
Sbjct: 241 CLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSW 300

Query: 301 IWLQWLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALL 360
           IWLQWLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALL
Sbjct: 301 IWLQWLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALL 360

Query: 361 WFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSP 420
           WFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSP
Sbjct: 361 WFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSP 420

Query: 421 LITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLM 480
           LITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLM
Sbjct: 421 LITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLM 480

Query: 481 VTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVF 540
           VTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVF
Sbjct: 481 VTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVF 540

Query: 541 SYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP 595
           SYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP
Sbjct: 541 SYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP 595


>gi|31795546 solute carrier family 13 (sodium/sulfate symporters),
           member 4 [Homo sapiens]
          Length = 626

 Score =  585 bits (1509), Expect = e-167
 Identities = 300/612 (49%), Positives = 406/612 (66%), Gaps = 33/612 (5%)

Query: 7   ILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLML 66
           +L  R+ L VV   L+LLPLP++  + EA CAY L V A +W++EA+PL   AL+P+ + 
Sbjct: 7   LLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAFLY 66

Query: 67  PMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLG 126
           P FG++ S +VA+ YFK+  LLL+GVIC+A ++EKWNLHKRIAL+MV+M G  P  L L 
Sbjct: 67  PFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLC 126

Query: 127 FMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEV---------EATQMTYFNGST 177
           FM  T  LSMWLSNTST AMVMPI EAV+Q++++AE E          EA  ++    ++
Sbjct: 127 FMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNS 186

Query: 178 NHGLEI----DES-------VNGHEINERKEKTKPVPGYNNDTGKISSKVELE------- 219
              LE+    +ES       ++   +N     T P+   N   GK     + +       
Sbjct: 187 QPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKPQVLTPS 246

Query: 220 -KNSGMRTKYRTKKGHVTRKLTCLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRC 278
            +   +  KYR+    +  K   L I+YS+TIGGLTTI GTST+LIF E+FN +YP    
Sbjct: 247 PRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQYPAAEV 306

Query: 279 LNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGKTKTVQQKACAEV-IKQEY 337
           +NFG+WF FSFP +LI+L++SW W+ WLFLG NFKE     K K  +++  +E  I++EY
Sbjct: 307 VNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEKRIQEEY 366

Query: 338 QKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFF 397
           +KLG I Y E+VT   FI+M +LWF+R+PGFVPGW + F E  G+ TD+TV++ +G L F
Sbjct: 367 EKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDSFF-EKKGYRTDATVSVFLGFLLF 425

Query: 398 LIPAKTLT---KTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGL 454
           LIPAK      K     +  +    P+ITWK+FQ  MPW+I ILVGGG+ALA G + SGL
Sbjct: 426 LIPAKKPCFGKKNDGENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASGSKSSGL 485

Query: 455 SKWIGNKLSPLGSLPAWLIILISSLMVTSLTEVASNPATITLFLPILSPLAEAIHVNPLY 514
           S WIGN++  L SLP W + L++ ++V+ +TE  SNPATIT+FLPIL  L+E +H+NPLY
Sbjct: 486 STWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLHINPLY 545

Query: 515 ILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIV 574
            LIP T+C SFA +LPV NPPNAIVFSYGH ++ DMVKAGLGVN++G+ +VM+ I TW V
Sbjct: 546 TLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAINTWGV 605

Query: 575 PMFDLYTYPSWA 586
            +F L TYP+WA
Sbjct: 606 SLFHLDTYPAWA 617


>gi|4506979 solute carrier family 13, member 2 isoform b [Homo
           sapiens]
          Length = 592

 Score =  518 bits (1335), Expect = e-147
 Identities = 278/602 (46%), Positives = 400/602 (66%), Gaps = 38/602 (6%)

Query: 10  YRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLMLPMF 69
           YR +L V F  ++LLPLPI++ +KEA CAY + ++A FW TEALPL+VTAL P ++ PM 
Sbjct: 11  YRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLILFPMM 70

Query: 70  GIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMS 129
           GI+ + +VA  Y KD +LL  G + +A ++E WNLHKRIAL+++++VGV PA L LGFM 
Sbjct: 71  GIVDASEVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLILGFML 130

Query: 130 STAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHGLEIDESVNG 189
            TAFLSMW+SNT+T+AM++PIA AV+ Q+ +++A     +     GS N   E+ E    
Sbjct: 131 VTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQASSNVEE-----GSNNPTFELQEP--- 182

Query: 190 HEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLTCLCIAYSST 249
              + +KE TK   G        SS+         R     K  H+T+ ++ LC+ YS++
Sbjct: 183 ---SPQKEVTKLDNGQALPVTSASSEG--------RAHLSQKHLHLTQCMS-LCVCYSAS 230

Query: 250 IGGLTTITGTSTNLIFAEYFNTRYP-DCRCLNFGSWFTFSFPAALIILLLSWIWLQWLFL 308
           IGG+ T+TGT+ NL+     N+ +P +   +NF SWF+F+FP  +I+LLL+W+WLQ LFL
Sbjct: 231 IGGIATLTGTAPNLVLQGQINSLFPQNGNVVNFASWFSFAFPTMVILLLLAWLWLQILFL 290

Query: 309 GFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGF 368
           GFNF++ F  G+    QQ+A   VI+ E++ LGP+ + E    +LF+I+ LLWF+R+PGF
Sbjct: 291 GFNFRKNFGIGEKMQEQQQAAYCVIQTEHRLLGPMTFAEKAISILFVILVLLWFTREPGF 350

Query: 369 VPGWSAL-FSEYPG--FATDSTVALLIGLLFFLIPAKT--LTKTTPT-GEIVAFDYSPLI 422
             GW  L F    G    +D TVA+ IG++ F+IP+K   LT+     G++ A     L+
Sbjct: 351 FLGWGNLAFPNAKGESMVSDGTVAIFIGIIMFIIPSKFPGLTQDPENPGKLKA--PLGLL 408

Query: 423 TWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVT 482
            WK     MPW+I +L+GGG+ALA G E SGLS+W+GNKL+PL S+PA  I +I SL+V 
Sbjct: 409 DWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVA 468

Query: 483 SLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSY 542
           + TE  SN AT T+FLPIL+ +A+AI ++PLY+++P TL TS AF+LPVA PPNAIVFS+
Sbjct: 469 TFTECTSNVATTTIFLPILASMAQAICLHPLYVMLPCTLATSLAFMLPVATPPNAIVFSF 528

Query: 543 GHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWA---------PAMSNET 593
           G LKV+DM +AG  +NI+GV ++ L I +W +P+F L+++PSWA         P+++N T
Sbjct: 529 GDLKVLDMARAGFLLNIIGVLIIALAINSWGIPLFSLHSFPSWAQSNTTAQCLPSLANTT 588

Query: 594 MP 595
            P
Sbjct: 589 TP 590


>gi|225637549 solute carrier family 13, member 2 isoform a [Homo
           sapiens]
          Length = 641

 Score =  495 bits (1275), Expect = e-140
 Identities = 278/651 (42%), Positives = 400/651 (61%), Gaps = 87/651 (13%)

Query: 10  YRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLMLPMF 69
           YR +L V F  ++LLPLPI++ +KEA CAY + ++A FW TEALPL+VTAL P ++ PM 
Sbjct: 11  YRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLILFPMM 70

Query: 70  GIMPSKK-------------------------------------------------VASA 80
           GI+ + +                                                 VA  
Sbjct: 71  GIVDASEIIQRPFPSSFESPGECQSVGMSVTASHNLGGTVGDSRVFPPLSHVSTCQVAVE 130

Query: 81  YFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSSTAFLSMWLSN 140
           Y KD +LL  G + +A ++E WNLHKRIAL+++++VGV PA L LGFM  TAFLSMW+SN
Sbjct: 131 YLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLILGFMLVTAFLSMWISN 190

Query: 141 TSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHGLEIDESVNGHEINERKEKTK 200
           T+T+AM++PIA AV+ Q+ +++A     +     GS N   E+ E       + +KE TK
Sbjct: 191 TATSAMMVPIAHAVLDQLHSSQASSNVEE-----GSNNPTFELQEP------SPQKEVTK 239

Query: 201 PVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLTCLCIAYSSTIGGLTTITGTS 260
              G        SS+         R     K  H+T+ ++ LC+ YS++IGG+ T+TGT+
Sbjct: 240 LDNGQALPVTSASSEG--------RAHLSQKHLHLTQCMS-LCVCYSASIGGIATLTGTA 290

Query: 261 TNLIFAEYFNTRYP-DCRCLNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCG 319
            NL+     N+ +P +   +NF SWF+F+FP  +I+LLL+W+WLQ LFLGFNF++ F  G
Sbjct: 291 PNLVLQGQINSLFPQNGNVVNFASWFSFAFPTMVILLLLAWLWLQILFLGFNFRKNFGIG 350

Query: 320 KTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSAL-FSE 378
           +    QQ+A   VI+ E++ LGP+ + E    +LF+I+ LLWF+R+PGF  GW  L F  
Sbjct: 351 EKMQEQQQAAYCVIQTEHRLLGPMTFAEKAISILFVILVLLWFTREPGFFLGWGNLAFPN 410

Query: 379 YPG--FATDSTVALLIGLLFFLIPAKT--LTKTTPT-GEIVAFDYSPLITWKEFQSFMPW 433
             G    +D TVA+ IG++ F+IP+K   LT+     G++ A     L+ WK     MPW
Sbjct: 411 AKGESMVSDGTVAIFIGIIMFIIPSKFPGLTQDPENPGKLKA--PLGLLDWKTVNQKMPW 468

Query: 434 DIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSLTEVASNPAT 493
           +I +L+GGG+ALA G E SGLS+W+GNKL+PL S+PA  I +I SL+V + TE  SN AT
Sbjct: 469 NIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATFTECTSNVAT 528

Query: 494 ITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKA 553
            T+FLPIL+ +A+AI ++PLY+++P TL TS AF+LPVA PPNAIVFS+G LKV+DM +A
Sbjct: 529 TTIFLPILASMAQAICLHPLYVMLPCTLATSLAFMLPVATPPNAIVFSFGDLKVLDMARA 588

Query: 554 GLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWA---------PAMSNETMP 595
           G  +NI+GV ++ L I +W +P+F L+++PSWA         P+++N T P
Sbjct: 589 GFLLNIIGVLIIALAINSWGIPLFSLHSFPSWAQSNTTAQCLPSLANTTTP 639


>gi|29171306 solute carrier family 13, member 5 isoform a [Homo
           sapiens]
          Length = 568

 Score =  491 bits (1264), Expect = e-139
 Identities = 258/596 (43%), Positives = 377/596 (63%), Gaps = 40/596 (6%)

Query: 5   SYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSL 64
           SY+  ++ F+ +  T L+LLPL I++  K   CAY + ++A +W TE +PL+VT+L+P L
Sbjct: 6   SYVSKFKSFVILFVTPLLLLPLVILMPAKFVRCAYVIILMAIYWCTEVIPLAVTSLMPVL 65

Query: 65  MLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLT 124
           + P+F I+ S++V   Y KD ++L +G + +A ++E+WNLHKRIAL+ ++ VG  PA L 
Sbjct: 66  LFPLFQILDSRQVCVQYMKDTNMLFLGGLIVAVAVERWNLHKRIALRTLLWVGAKPARLM 125

Query: 125 LGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHGLEID 184
           LGFM  TA LSMW+SNT+T AM++PI EA++QQ+       EAT     + +T  GLE+ 
Sbjct: 126 LGFMGVTALLSMWISNTATTAMMVPIVEAILQQM-------EAT-----SAATEAGLELV 173

Query: 185 ESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLTCLCI 244
           +          K K K +PG         S+V  E  +  + + + +K  + + +T LCI
Sbjct: 174 D----------KGKAKELPG---------SQVIFEGPTLGQQEDQERK-RLCKAMT-LCI 212

Query: 245 AYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCL-NFGSWFTFSFPAALIILLLSWIWL 303
            Y+++IGG  T+TGT  N++     N  +PD + L NF SWF F+FP  L++LL +W+WL
Sbjct: 213 CYAASIGGTATLTGTGPNVVLLGQMNELFPDSKDLVNFASWFAFAFPNMLVMLLFAWLWL 272

Query: 304 QWLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFS 363
           Q++++ FNFK+ + CG      +KA  +V+++EY+KLGP+ + EI  L+ F ++ +LWFS
Sbjct: 273 QFVYMRFNFKKSWGCGLESKKNEKAALKVLQEEYRKLGPLSFAEINVLICFFLLVILWFS 332

Query: 364 RDPGFVPGWS--ALFSEYPGFATDSTVALLIGLLFFLIPAK----TLTKTTPTGEIVAFD 417
           RDPGF+PGW   A       + +D+TVA+ +  L F++P++         T       F 
Sbjct: 333 RDPGFMPGWLTVAWVEGETKYVSDATVAIFVATLLFIVPSQKPKFNFRSQTEEERKTPFY 392

Query: 418 YSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILIS 477
             PL+ WK  Q  +PW I +L+GGGFALA G E SGLS W+G ++ PL ++P   I LI 
Sbjct: 393 PPPLLDWKVTQEKVPWGIVLLLGGGFALAKGSEASGLSVWMGKQMEPLHAVPPAAITLIL 452

Query: 478 SLMVTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNA 537
           SL+V   TE  SN AT TLFLPI + ++ +I +NPLYI++P TL  SFAF+LPVA PPNA
Sbjct: 453 SLLVAVFTECTSNVATTTLFLPIFASMSRSIGLNPLYIMLPCTLSASFAFMLPVATPPNA 512

Query: 538 IVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNET 593
           IVF+YGHLKV DMVK G+ +NI+GV  V L + TW   +FDL  +P WA     ET
Sbjct: 513 IVFTYGHLKVADMVKTGVIMNIIGVFCVFLAVNTWGRAIFDLDHFPDWANVTHIET 568


>gi|31377715 solute carrier family 13 member 3 isoform a [Homo
           sapiens]
          Length = 602

 Score =  463 bits (1191), Expect = e-130
 Identities = 243/585 (41%), Positives = 365/585 (62%), Gaps = 20/585 (3%)

Query: 11  RRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLMLPMFG 70
           RR L ++FT L LLP+   L  KE  C + + ++A +W TEALPLSVTALLP ++ P  G
Sbjct: 15  RRLLVLLFTPLALLPVVFALPPKEGRCLFVILLMAVYWCTEALPLSVTALLPIVLFPFMG 74

Query: 71  IMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSS 130
           I+PS KV   YF D + L +  + +A++IE+WNLH+RIALK++M+VGV PA L LG M +
Sbjct: 75  ILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQPARLILGMMVT 134

Query: 131 TAFLSMWLSNTSTAAMVMPIAEAVVQQIINA-EAEVEATQMTYFNGSTNHGLEIDESVNG 189
           T+FLSMWLSNT++ AM++PIA A+++ +    E   + +Q +  N +           NG
Sbjct: 135 TSFLSMWLSNTASTAMMLPIANAILKSLFGQKEVRKDPSQESEENTAAVRR-------NG 187

Query: 190 HEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTK--KGHVTRKLTCLCIAYS 247
                 + +        +  G+    ++L  +S    +YR    KG +      + I YS
Sbjct: 188 LHTVPTEMQFLASTEAKDHPGETEVPLDLPADSRKEDEYRRNIWKGFL------ISIPYS 241

Query: 248 STIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQWLF 307
           ++IGG  T+TGT+ NLI      + +P C  +NFGSWF F+FP  L+ LL  W+W+ +L+
Sbjct: 242 ASIGGTATLTGTAPNLILLGQLKSFFPQCDVVNFGSWFIFAFPLMLLFLLAGWLWISFLY 301

Query: 308 LGFNFKEMFKC-GKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDP 366
            G +F+   K   + +T  +     VI++EYQ LGPI++ E    +LF + A+L F+RDP
Sbjct: 302 GGLSFRGWRKNKSEIRTNAEDRARAVIREEYQNLGPIKFAEQAVFILFCMFAILLFTRDP 361

Query: 367 GFVPGWSALFSEYPGFATDSTVAL-LIGLLFFLIPAKTLTKTTPTGEIVAFDYSPLITWK 425
            F+PGW++LF+  PGF +D+   + ++ +LFF    +   K     +    +  PL+TWK
Sbjct: 362 KFIPGWASLFN--PGFLSDAVTGVAIVTILFFFPSQRPSLKWWFDFKAPNTETEPLLTWK 419

Query: 426 EFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSLT 485
           + Q  +PW+I +L+GGGFA+A GCEESGLS WIG +L PL ++P  L +L+ ++++   T
Sbjct: 420 KAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFT 479

Query: 486 EVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHL 545
           E ASN ATI +FLP+L+ LA  + V+PLY++IP T+  SFAF+LPV+ PPN+I F+ GHL
Sbjct: 480 EFASNTATIIIFLPVLAELAIRLRVHPLYLMIPGTVGCSFAFMLPVSTPPNSIAFASGHL 539

Query: 546 KVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMS 590
            V DMV+ GL +N++GV ++ L + TW   +F L T+P WA   S
Sbjct: 540 LVKDMVRTGLLMNLMGVLLLSLAMNTWAQTIFQLGTFPDWADMYS 584


>gi|225637552 solute carrier family 13, member 2 isoform c [Homo
           sapiens]
          Length = 549

 Score =  453 bits (1166), Expect = e-127
 Identities = 250/555 (45%), Positives = 363/555 (65%), Gaps = 39/555 (7%)

Query: 57  VTALLPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMV 116
           +   +P L+LP+  ++PSK VA  Y KD +LL  G + +A ++E WNLHKRIAL+++++V
Sbjct: 16  IVFFVPILLLPLPILVPSK-VAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIV 74

Query: 117 GVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGS 176
           GV PA L LGFM  TAFLSMW+SNT+T+AM++PIA AV+ Q+ +++A     +     GS
Sbjct: 75  GVRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQASSNVEE-----GS 129

Query: 177 TNHGLEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVT 236
            N   E+ E       + +KE TK   G        SS+         R     K  H+T
Sbjct: 130 NNPTFELQEP------SPQKEVTKLDNGQALPVTSASSEG--------RAHLSQKHLHLT 175

Query: 237 RKLTCLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYP-DCRCLNFGSWFTFSFPAALII 295
           + ++ LC+ YS++IGG+ T+TGT+ NL+     N+ +P +   +NF SWF+F+FP  +I+
Sbjct: 176 QCMS-LCVCYSASIGGIATLTGTAPNLVLQGQINSLFPQNGNVVNFASWFSFAFPTMVIL 234

Query: 296 LLLSWIWLQWLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFI 355
           LLL+W+WLQ LFLGFNF++ F  G+    QQ+A   VI+ E++ LGP+ + E    +LF+
Sbjct: 235 LLLAWLWLQILFLGFNFRKNFGIGEKMQEQQQAAYCVIQTEHRLLGPMTFAEKAISILFV 294

Query: 356 IMALLWFSRDPGFVPGWSAL-FSEYPG--FATDSTVALLIGLLFFLIPAKT--LTKTTPT 410
           I+ LLWF+R+PGF  GW  L F    G    +D TVA+ IG++ F+IP+K   LT+    
Sbjct: 295 ILVLLWFTREPGFFLGWGNLAFPNAKGESMVSDGTVAIFIGIIMFIIPSKFPGLTQDPEN 354

Query: 411 -GEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLP 469
            G++ A     L+ WK     MPW+I +L+GGG+ALA G E SGLS+W+GNKL+PL S+P
Sbjct: 355 PGKLKA--PLGLLDWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQSVP 412

Query: 470 AWLIILISSLMVTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLL 529
           A  I +I SL+V + TE  SN AT T+FLPIL+ +A+AI ++PLY+++P TL TS AF+L
Sbjct: 413 APAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAICLHPLYVMLPCTLATSLAFML 472

Query: 530 PVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWA--- 586
           PVA PPNAIVFS+G LKV+DM +AG  +NI+GV ++ L I +W +P+F L+++PSWA   
Sbjct: 473 PVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSWGIPLFSLHSFPSWAQSN 532

Query: 587 ------PAMSNETMP 595
                 P+++N T P
Sbjct: 533 TTAQCLPSLANTTTP 547



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 4/80 (5%)

Query: 26  LPIVLHTKEAECAYTLFVVATFWLTEALPLSV-TALLPSLMLPMFGIMPSKKVASAYFKD 84
           LPI+    +A C + L+V+    L  +L   +  A  P+ ++  FG +    +A A    
Sbjct: 441 LPILASMAQAICLHPLYVMLPCTLATSLAFMLPVATPPNAIVFSFGDLKVLDMARA---G 497

Query: 85  FHLLLIGVICLATSIEKWNL 104
           F L +IGV+ +A +I  W +
Sbjct: 498 FLLNIIGVLIIALAINSWGI 517


>gi|58761541 solute carrier family 13 member 3 isoform b [Homo
           sapiens]
          Length = 555

 Score =  437 bits (1124), Expect = e-122
 Identities = 230/552 (41%), Positives = 346/552 (62%), Gaps = 20/552 (3%)

Query: 44  VATFWLTEALPLSVTALLPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWN 103
           +A +W TEALPLSVTALLP ++ P  GI+PS KV   YF D + L +  + +A++IE+WN
Sbjct: 1   MAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWN 60

Query: 104 LHKRIALKMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINA-E 162
           LH+RIALK++M+VGV PA L LG M +T+FLSMWLSNT++ AM++PIA A+++ +    E
Sbjct: 61  LHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLFGQKE 120

Query: 163 AEVEATQMTYFNGSTNHGLEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNS 222
              + +Q +  N +           NG      + +        +  G+    ++L  +S
Sbjct: 121 VRKDPSQESEENTAAVRR-------NGLHTVPTEMQFLASTEAKDHPGETEVPLDLPADS 173

Query: 223 GMRTKYRTK--KGHVTRKLTCLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLN 280
               +YR    KG +      + I YS++IGG  T+TGT+ NLI      + +P C  +N
Sbjct: 174 RKEDEYRRNIWKGFL------ISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQCDVVN 227

Query: 281 FGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKC-GKTKTVQQKACAEVIKQEYQK 339
           FGSWF F+FP  L+ LL  W+W+ +L+ G +F+   K   + +T  +     VI++EYQ 
Sbjct: 228 FGSWFIFAFPLMLLFLLAGWLWISFLYGGLSFRGWRKNKSEIRTNAEDRARAVIREEYQN 287

Query: 340 LGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVAL-LIGLLFFL 398
           LGPI++ E    +LF + A+L F+RDP F+PGW++LF+  PGF +D+   + ++ +LFF 
Sbjct: 288 LGPIKFAEQAVFILFCMFAILLFTRDPKFIPGWASLFN--PGFLSDAVTGVAIVTILFFF 345

Query: 399 IPAKTLTKTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWI 458
              +   K     +    +  PL+TWK+ Q  +PW+I +L+GGGFA+A GCEESGLS WI
Sbjct: 346 PSQRPSLKWWFDFKAPNTETEPLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWI 405

Query: 459 GNKLSPLGSLPAWLIILISSLMVTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIP 518
           G +L PL ++P  L +L+ ++++   TE ASN ATI +FLP+L+ LA  + V+PLY++IP
Sbjct: 406 GGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHPLYLMIP 465

Query: 519 STLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFD 578
            T+  SFAF+LPV+ PPN+I F+ GHL V DMV+ GL +N++GV ++ L + TW   +F 
Sbjct: 466 GTVGCSFAFMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTWAQTIFQ 525

Query: 579 LYTYPSWAPAMS 590
           L T+P WA   S
Sbjct: 526 LGTFPDWADMYS 537


>gi|219802232 solute carrier family 13, member 5 isoform b [Homo
           sapiens]
          Length = 522

 Score =  403 bits (1036), Expect = e-112
 Identities = 228/597 (38%), Positives = 333/597 (55%), Gaps = 88/597 (14%)

Query: 5   SYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSL 64
           SY+  ++ F+ +  T L+LLPL I++  K   CAY + ++A +W TE +PL+VT+L+P L
Sbjct: 6   SYVSKFKSFVILFVTPLLLLPLVILMPAKFVRCAYVIILMAIYWCTEVIPLAVTSLMPVL 65

Query: 65  MLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLT 124
           + P+F I+ S++V   Y KD ++L +G + +A ++E+WNLHKRIAL+ ++ VG  PA L 
Sbjct: 66  LFPLFQILDSRQVCVQYMKDTNMLFLGGLIVAVAVERWNLHKRIALRTLLWVGAKPARLM 125

Query: 125 LGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHGLEID 184
           LGFM  TA LSMW+SNT+T AM++PI EA++QQ       +EAT     + +T  GLE+ 
Sbjct: 126 LGFMGVTALLSMWISNTATTAMMVPIVEAILQQ-------MEAT-----SAATEAGLELV 173

Query: 185 ESVNGHEINERKEKTKPVPGYNNDTGKISSKVELE-KNSGMRTKYRTKKGHVTRKLTCLC 243
           +          K K K +PG         S+V  E    G +     K+     K   LC
Sbjct: 174 D----------KGKAKELPG---------SQVIFEGPTLGQQEDQERKR---LCKAMTLC 211

Query: 244 IAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCL-NFGSWFTFSFPAALIILLLSWIW 302
           I Y+++IGG  T+TGT  N++     N  +PD + L NF SWF F+FP  L++LL +W+W
Sbjct: 212 ICYAASIGGTATLTGTGPNVVLLGQMNELFPDSKDLVNFASWFAFAFPNMLVMLLFAWLW 271

Query: 303 LQWLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWF 362
           LQ++++ FNFK+ + CG      +KA  +V+++EY+KLGP+ + EI  L+ F ++ +LWF
Sbjct: 272 LQFVYMRFNFKKSWGCGLESKKNEKAALKVLQEEYRKLGPLSFAEINVLICFFLLVILWF 331

Query: 363 SRDPGFVPGW--SALFSEYPGFATDSTVALLIGLLFFLIPAK----TLTKTTPTGEIVAF 416
           SRDPGF+PGW   A       + +D+TVA+ +  L F++P++         T       F
Sbjct: 332 SRDPGFMPGWLTVAWVEGETKYVSDATVAIFVATLLFIVPSQKPKFNFRSQTEEERKTPF 391

Query: 417 DYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILI 476
              PL+ WK  Q  +PW I +L+GGGFALA G E SGLS W+G ++ PL ++P   I LI
Sbjct: 392 YPPPLLDWKVTQEKVPWGIVLLLGGGFALAKGSEASGLSVWMGKQMEPLHAVPPAAITLI 451

Query: 477 SSLMVTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPN 536
            SL+V   TE  SN AT TLFLPI +                                  
Sbjct: 452 LSLLVAVFTECTSNVATTTLFLPIFA---------------------------------- 477

Query: 537 AIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNET 593
                        MVK G+ +NI+GV  V L + TW   +FDL  +P WA     ET
Sbjct: 478 ------------SMVKTGVIMNIIGVFCVFLAVNTWGRAIFDLDHFPDWANVTHIET 522


>gi|157266326 oculocutaneous albinism II [Homo sapiens]
          Length = 838

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 40/173 (23%), Positives = 74/173 (42%), Gaps = 13/173 (7%)

Query: 421 LITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLM 480
           ++ W +F++        L+ G   L     E+G   +   K   L     W +I++  L+
Sbjct: 379 VVEWIDFETLA------LLFGMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIMLCLI 432

Query: 481 VTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSF-AFLLPVANPPNAIV 539
              L+    N  T+ LF P+   L E ++++P  +LI   + T+       + +PPN I+
Sbjct: 433 AAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVII 492

Query: 540 FSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNE 592
            S   L+ + +  AG        A + +GIC  ++  F L     W   + N+
Sbjct: 493 VSNQELRKMGLDFAGF------TAHMFIGICLVLLVCFPLLRLLYWNRKLYNK 539


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 33.1 bits (74), Expect = 0.74
 Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 7/67 (10%)

Query: 479  LMVTSLTEVASNPATITLFLPIL-SPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNA 537
            L VTSL+ V++   T    LP+  +  A   H  PL + IPS++ T     LPV +P +A
Sbjct: 3681 LPVTSLSSVSTGDTTP---LPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSA 3737

Query: 538  IVFSYGH 544
               S GH
Sbjct: 3738 ---STGH 3741



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 4/62 (6%)

Query: 484  LTEVASNPATITLFLPILSPLAEAI-HVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSY 542
            +T+ +S     T  LP+ SP + +  H  PL++ IPS+  T     LPV    +A   S 
Sbjct: 3331 VTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSA---ST 3387

Query: 543  GH 544
            GH
Sbjct: 3388 GH 3389



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 21/62 (33%), Positives = 34/62 (54%), Gaps = 4/62 (6%)

Query: 477  SSLMVTSLTEVASNPATITLFLPILSPLAEAI-HVNPLYILIPSTLCTSFAFLLPVANPP 535
            +SL+VT  + V++   T    LP+ S  + +  HV PL++  PS+  T  A  LPV +  
Sbjct: 1263 TSLLVTDTSSVSTGDTTP---LPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLS 1319

Query: 536  NA 537
            +A
Sbjct: 1320 SA 1321



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 21/62 (33%), Positives = 34/62 (54%), Gaps = 4/62 (6%)

Query: 477  SSLMVTSLTEVASNPATITLFLPILSPLAEAI-HVNPLYILIPSTLCTSFAFLLPVANPP 535
            +SL+VT  + V++   T    LP+ S  + +  HV PL++  PS+  T  A  LPV +  
Sbjct: 1471 TSLLVTDTSSVSTGDTTP---LPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLS 1527

Query: 536  NA 537
            +A
Sbjct: 1528 SA 1529



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 4/62 (6%)

Query: 477  SSLMVTSLTEVASNPATITLFLPILSPLAEAI-HVNPLYILIPSTLCTSFAFLLPVANPP 535
            +SL VTSL+ V++   T    LP+ SP + +  H  PL++   S+  T  A  LPV +  
Sbjct: 2271 TSLPVTSLSSVSTGDTTP---LPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLS 2327

Query: 536  NA 537
            +A
Sbjct: 2328 SA 2329



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 4/79 (5%)

Query: 479  LMVTSLTEVASNPATITLFLPILSPLAEAI-HVNPLYILIPSTLCTSFAFLLPVANPPNA 537
            L VTSL+ V++   T    LP+ SP + +  H  PL +   S+  T  A  LPV +  +A
Sbjct: 2961 LPVTSLSSVSTGDTTP---LPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSA 3017

Query: 538  IVFSYGHLKVIDMVKAGLG 556
                   L V D   A  G
Sbjct: 3018 STGDTTPLPVTDTSSASTG 3036



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 10/82 (12%)

Query: 479  LMVTSLTEVASNPATITLFLPILSPLAEAI-HVNPLYILIPSTLCTSFAFLLPVANPPNA 537
            L VTSL+  ++   T    LP+ SP + +  H  PL++   S++ T     LPV +  +A
Sbjct: 2321 LPVTSLSSASTGDTTP---LPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSA 2377

Query: 538  IVFSYGH---LKVIDMVKAGLG 556
               S GH   L V D   A  G
Sbjct: 2378 ---SSGHTTPLPVTDASSASTG 2396



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 7/67 (10%)

Query: 479  LMVTSLTEVASNPATITLFLPIL-SPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNA 537
            L VTS +  ++  AT    LP+  +  A   H NPL++  PS+  T  A  LPV +  +A
Sbjct: 2897 LHVTSPSSASTGHATP---LPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSA 2953

Query: 538  IVFSYGH 544
               S GH
Sbjct: 2954 ---STGH 2957


>gi|38348366 suprabasin [Homo sapiens]
          Length = 247

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 8/104 (7%)

Query: 134 LSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHGLEIDESVNGHE-- 191
           LS W ++      V+   E + + + NAE EV        +G T+ G E+++  NG    
Sbjct: 19  LSGWAASDDPIEKVI---EGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNM 75

Query: 192 -INERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGH 234
             +  KE  K V G N+   K++   E+    G   K   K GH
Sbjct: 76  GSHTGKELDKGVQGLNHGMDKVAH--EINHGIGQAGKEAEKLGH 117


>gi|239749916 PREDICTED: hypothetical protein XP_002347212 [Homo
           sapiens]
          Length = 391

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 31/124 (25%), Positives = 62/124 (50%), Gaps = 10/124 (8%)

Query: 462 LSPLGSLPAWLIILISSLMVTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPS-- 519
           ++PL  +  +LI++ +SL+V  +T + S P ++ L  P ++ L   + + PL ++I S  
Sbjct: 185 ITPLVMVITFLIVVNTSLVVVLITLIVSPPPSLWLSAPCITSL--FVVIIPLVVVITSLI 242

Query: 520 TLCTSFAFLL--PVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMF 577
            + TS   +L   +   P+ IV     +  + +V A L V  + + VV+  +   I  + 
Sbjct: 243 VVITSLVVVLIAVIVVTPSLIVV----ISSLVVVIASLVVVFISLIVVISSLIVVITSLV 298

Query: 578 DLYT 581
            + T
Sbjct: 299 VVIT 302


>gi|239744219 PREDICTED: hypothetical protein XP_002343076 [Homo
           sapiens]
          Length = 398

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 31/124 (25%), Positives = 62/124 (50%), Gaps = 10/124 (8%)

Query: 462 LSPLGSLPAWLIILISSLMVTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPS-- 519
           ++PL  +  +LI++ +SL+V  +T + S P ++ L  P ++ L   + + PL ++I S  
Sbjct: 192 ITPLVMVITFLIVVNTSLVVVLITLIVSPPPSLWLSAPCITSL--FVVIIPLVVVITSLI 249

Query: 520 TLCTSFAFLL--PVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMF 577
            + TS   +L   +   P+ IV     +  + +V A L V  + + VV+  +   I  + 
Sbjct: 250 VVITSLVVVLIAVIVVTPSLIVV----ISSLVVVIASLVVVFISLIVVISSLIVVITSLV 305

Query: 578 DLYT 581
            + T
Sbjct: 306 VVIT 309


>gi|102467481 sphingomyelin phosphodiesterase 4 isoform 2 [Homo
           sapiens]
          Length = 866

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 13/40 (32%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query: 15  FVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALP 54
           F   +++   PLP+ LH + ++CAY  F++   +L+  LP
Sbjct: 199 FFALSLITQKPLPVSLHVRTSDCAY--FILVDRYLSWFLP 236


>gi|102467484 sphingomyelin phosphodiesterase 4 isoform 1 [Homo
           sapiens]
          Length = 837

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 13/40 (32%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query: 15  FVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALP 54
           F   +++   PLP+ LH + ++CAY  F++   +L+  LP
Sbjct: 199 FFALSLITQKPLPVSLHVRTSDCAY--FILVDRYLSWFLP 236


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.138    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,476,007
Number of Sequences: 37866
Number of extensions: 902007
Number of successful extensions: 2706
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2595
Number of HSP's gapped (non-prelim): 73
length of query: 595
length of database: 18,247,518
effective HSP length: 108
effective length of query: 487
effective length of database: 14,157,990
effective search space: 6894941130
effective search space used: 6894941130
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.