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Search of human proteins with 19923830
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923830 pre-B-cell leukemia homeobox interacting protein 1
[Homo sapiens]
(731 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923830 pre-B-cell leukemia homeobox interacting protein 1 [... 1490 0.0
gi|75677574 cell cycle progression 1 isoform 2 [Homo sapiens] 116 6e-26
gi|75677585 cell cycle progression 1 isoform 1 [Homo sapiens] 116 6e-26
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 55 2e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 54 4e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 54 5e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 54 5e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 53 1e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 53 1e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 53 1e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 53 1e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 53 1e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 53 1e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 53 1e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 53 1e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 53 1e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 53 1e-06
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 52 2e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 51 3e-06
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 50 7e-06
gi|148746195 trichohyalin [Homo sapiens] 50 7e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 50 1e-05
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 48 4e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 48 4e-05
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 47 5e-05
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 47 6e-05
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 46 1e-04
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 46 1e-04
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens] 46 1e-04
gi|117168269 coiled-coil domain containing 33 isoform 2 [Homo sa... 46 1e-04
>gi|19923830 pre-B-cell leukemia homeobox interacting protein 1
[Homo sapiens]
Length = 731
Score = 1490 bits (3858), Expect = 0.0
Identities = 731/731 (100%), Positives = 731/731 (100%)
Query: 1 MASCPDSDNSWVLAGSESLPVETLGPASRMDPESERALQAPHSPSKTDGKELAGTMDGEG 60
MASCPDSDNSWVLAGSESLPVETLGPASRMDPESERALQAPHSPSKTDGKELAGTMDGEG
Sbjct: 1 MASCPDSDNSWVLAGSESLPVETLGPASRMDPESERALQAPHSPSKTDGKELAGTMDGEG 60
Query: 61 TLFQTESPQSGSILTEETEVKGTLEGDVCGVEPPGPGDTVVQGDLQETTVVTGLGPDTQD 120
TLFQTESPQSGSILTEETEVKGTLEGDVCGVEPPGPGDTVVQGDLQETTVVTGLGPDTQD
Sbjct: 61 TLFQTESPQSGSILTEETEVKGTLEGDVCGVEPPGPGDTVVQGDLQETTVVTGLGPDTQD 120
Query: 121 LEGQSPPQSLPSTPKAAWIREEGRCSSSDDDTDVDMEGLRRRRGREAGPPQPMVPLAVEN 180
LEGQSPPQSLPSTPKAAWIREEGRCSSSDDDTDVDMEGLRRRRGREAGPPQPMVPLAVEN
Sbjct: 121 LEGQSPPQSLPSTPKAAWIREEGRCSSSDDDTDVDMEGLRRRRGREAGPPQPMVPLAVEN 180
Query: 181 QAGGEGAGGELGISLNMCLLGALVLLGLGVLLFSGGLSESETGPMEEVERQVLPDPEVLE 240
QAGGEGAGGELGISLNMCLLGALVLLGLGVLLFSGGLSESETGPMEEVERQVLPDPEVLE
Sbjct: 181 QAGGEGAGGELGISLNMCLLGALVLLGLGVLLFSGGLSESETGPMEEVERQVLPDPEVLE 240
Query: 241 AVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLM 300
AVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLM
Sbjct: 241 AVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLM 300
Query: 301 HQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGP 360
HQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGP
Sbjct: 301 HQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGP 360
Query: 361 QGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDAS 420
QGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDAS
Sbjct: 361 QGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDAS 420
Query: 421 RGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWD 480
RGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWD
Sbjct: 421 RGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWD 480
Query: 481 GQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKE 540
GQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKE
Sbjct: 481 GQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKE 540
Query: 541 PPRKSGSFHSSGEKQKQPRWREGTKDSHDPLPSWAELLRPKYRAPQGCSGVDECARQEGL 600
PPRKSGSFHSSGEKQKQPRWREGTKDSHDPLPSWAELLRPKYRAPQGCSGVDECARQEGL
Sbjct: 541 PPRKSGSFHSSGEKQKQPRWREGTKDSHDPLPSWAELLRPKYRAPQGCSGVDECARQEGL 600
Query: 601 TFFGTELAPVRQQELASLLRTYLARLPWAGQLTKELPLSPAFFGEDGIFRHDRLRFRDFV 660
TFFGTELAPVRQQELASLLRTYLARLPWAGQLTKELPLSPAFFGEDGIFRHDRLRFRDFV
Sbjct: 601 TFFGTELAPVRQQELASLLRTYLARLPWAGQLTKELPLSPAFFGEDGIFRHDRLRFRDFV 660
Query: 661 DALEDSLEEVAVQQTGDDDEVDDFEDFIFSHFFGDKALKKRSGKKDKHSQSPRAAGPREG 720
DALEDSLEEVAVQQTGDDDEVDDFEDFIFSHFFGDKALKKRSGKKDKHSQSPRAAGPREG
Sbjct: 661 DALEDSLEEVAVQQTGDDDEVDDFEDFIFSHFFGDKALKKRSGKKDKHSQSPRAAGPREG 720
Query: 721 HSHSHHHHHRG 731
HSHSHHHHHRG
Sbjct: 721 HSHSHHHHHRG 731
>gi|75677574 cell cycle progression 1 isoform 2 [Homo sapiens]
Length = 757
Score = 116 bits (291), Expect = 6e-26
Identities = 172/771 (22%), Positives = 309/771 (40%), Gaps = 124/771 (16%)
Query: 6 DSDNS--WVLAGSESLPVETLG---------PA---SRMDPESERALQAPHSPSKTDGKE 51
DSD+S W + E +E L PA S ++ E +ALQ S +G
Sbjct: 7 DSDSSCGWTVISHEGSDIEMLNSVTPTDSCEPAPECSSLEQEELQALQIEQGESSQNGTV 66
Query: 52 LAGTMDGEGTLFQTESPQSGSILTEETEVK------GTL--EGDVCGVEPPGPGDTVVQG 103
L E T + S +I EE ++ GT + D+ +EPP + G
Sbjct: 67 LM-----EETAYPALEETSSTIEAEEQKIPEDSIYIGTASDDSDIVTLEPPKLEEI---G 118
Query: 104 DLQETTVVTGLGPDTQDLEGQSPPQSLPSTPKAAWIREEGRCSSSDDDT-DVDMEGLRRR 162
+ + V + ++ S Q P+ + + SS D+T + RRR
Sbjct: 119 NQEVVIVEEAQSSEDFNMGSSSSSQYTFCQPETVFSSQPSDDESSSDETSNQPSPAFRRR 178
Query: 163 RGRE----AGPPQPMVPLAVENQAGGEGAGGELGISLNMCLLGALVL-LGLGVLLFSGGL 217
R R+ A + + E + E + + LN C++ ALV+ + +G F G +
Sbjct: 179 RARKKTVSASESEDRLVAEQETEPSKELSKRQFSSGLNKCVILALVIAISMGFGHFYGTI 238
Query: 218 SESETGPMEEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAK 277
+ +++ R++ D + D +D L + Q + + K K
Sbjct: 239 QIQKR---QQLVRKIHEDE-----LNDMKDYLSQCQQ-----------EQESFIDYKSLK 279
Query: 278 ENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRAR 337
EN L + E S Q L EN LR +L++ E +L+ EL +LR +
Sbjct: 280 EN-----LARCWTLTEAEKMSFETQKTNLATENQYLRVSLEKEEKALSSLQEELNKLREQ 334
Query: 338 LQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQE 397
++ LE +G + + ++ +++ E++ + SFL Q+E L EA+ L++E
Sbjct: 335 IRILED---KGTSTELV------KENQKLKQHLEEEKQKKHSFLSQRETLLTEAKMLKRE 385
Query: 398 LERQR----RLLGSVQQDLERSLQDASRGDPAHAG----------LAELGHRLAQKLQGL 443
LER+R L G +QQ L S + L EL +L + Q
Sbjct: 386 LERERLVTTALRGELQQLSGSQLHGKSDSPNVYTEKKEIAILRERLTELERKLTFEQQRS 445
Query: 444 ENW--------GQDPGVSANASKAWHQKSHFQNSRE----WSGKEKWWDGQRDRKAEHWK 491
+ W Q+ + K + SH ++ ++ +D ++ E +
Sbjct: 446 DLWERLYVEAKDQNGKQGTDGKKKGGRGSHRAKNKSKETFLGSVKETFDAMKNSTKEFVR 505
Query: 492 HKKE------ESGRERKKNWGGQEDREPAGRWKEGRPRV-EESGSKKEGKRQGPKEPPR- 543
H KE E+ +E K + + +K+ + +E G+K+ G + E PR
Sbjct: 506 HHKEKIKQAKEAVKENLKKFSDSV-KSTFRHFKDTTKNIFDEKGNKRFGATKEAAEKPRT 564
Query: 544 -------------------KSGSFHSSGEKQKQPRWREGTKDSHDPLPSWAELLRPKYRA 584
+ + + G K+K ++E K+++ S R +
Sbjct: 565 VFSDYLHPQYKAPTENHHNRGPTMQNDGRKEKPVHFKEFRKNTNSKKCSPGHDCRENSHS 624
Query: 585 -PQGCSGVDECARQEGLTFFGTELAPVRQQELASLLRTYLARLPWAGQLTKELPLSPAFF 643
+ CSGV +CA+QE ++ F T + P+R E +++ Y+ + EL F
Sbjct: 625 FRKACSGVFDCAQQESMSLFNTVVNPIRMDEFRQIIQRYMLKELDTFCHWNELDQFINKF 684
Query: 644 GEDGIFRHDRLRFRDFVDALEDSLEEVAVQQTGDDDEVDDFEDFIFSHFFG 694
+G+F HD+ F DFV+ ++D L + + +D + +++I+ HFFG
Sbjct: 685 FLNGVFIHDQKLFTDFVNDVKDYLRNMKEYEVDNDGVFEKLDEYIYRHFFG 735
>gi|75677585 cell cycle progression 1 isoform 1 [Homo sapiens]
Length = 757
Score = 116 bits (291), Expect = 6e-26
Identities = 172/771 (22%), Positives = 309/771 (40%), Gaps = 124/771 (16%)
Query: 6 DSDNS--WVLAGSESLPVETLG---------PA---SRMDPESERALQAPHSPSKTDGKE 51
DSD+S W + E +E L PA S ++ E +ALQ S +G
Sbjct: 7 DSDSSCGWTVISHEGSDIEMLNSVTPTDSCEPAPECSSLEQEELQALQIEQGESSQNGTV 66
Query: 52 LAGTMDGEGTLFQTESPQSGSILTEETEVK------GTL--EGDVCGVEPPGPGDTVVQG 103
L E T + S +I EE ++ GT + D+ +EPP + G
Sbjct: 67 LM-----EETAYPALEETSSTIEAEEQKIPEDSIYIGTASDDSDIVTLEPPKLEEI---G 118
Query: 104 DLQETTVVTGLGPDTQDLEGQSPPQSLPSTPKAAWIREEGRCSSSDDDT-DVDMEGLRRR 162
+ + V + ++ S Q P+ + + SS D+T + RRR
Sbjct: 119 NQEVVIVEEAQSSEDFNMGSSSSSQYTFCQPETVFSSQPSDDESSSDETSNQPSPAFRRR 178
Query: 163 RGRE----AGPPQPMVPLAVENQAGGEGAGGELGISLNMCLLGALVL-LGLGVLLFSGGL 217
R R+ A + + E + E + + LN C++ ALV+ + +G F G +
Sbjct: 179 RARKKTVSASESEDRLVAEQETEPSKELSKRQFSSGLNKCVILALVIAISMGFGHFYGTI 238
Query: 218 SESETGPMEEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAK 277
+ +++ R++ D + D +D L + Q + + K K
Sbjct: 239 QIQKR---QQLVRKIHEDE-----LNDMKDYLSQCQQ-----------EQESFIDYKSLK 279
Query: 278 ENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRAR 337
EN L + E S Q L EN LR +L++ E +L+ EL +LR +
Sbjct: 280 EN-----LARCWTLTEAEKMSFETQKTNLATENQYLRVSLEKEEKALSSLQEELNKLREQ 334
Query: 338 LQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQE 397
++ LE +G + + ++ +++ E++ + SFL Q+E L EA+ L++E
Sbjct: 335 IRILED---KGTSTELV------KENQKLKQHLEEEKQKKHSFLSQRETLLTEAKMLKRE 385
Query: 398 LERQR----RLLGSVQQDLERSLQDASRGDPAHAG----------LAELGHRLAQKLQGL 443
LER+R L G +QQ L S + L EL +L + Q
Sbjct: 386 LERERLVTTALRGELQQLSGSQLHGKSDSPNVYTEKKEIAILRERLTELERKLTFEQQRS 445
Query: 444 ENW--------GQDPGVSANASKAWHQKSHFQNSRE----WSGKEKWWDGQRDRKAEHWK 491
+ W Q+ + K + SH ++ ++ +D ++ E +
Sbjct: 446 DLWERLYVEAKDQNGKQGTDGKKKGGRGSHRAKNKSKETFLGSVKETFDAMKNSTKEFVR 505
Query: 492 HKKE------ESGRERKKNWGGQEDREPAGRWKEGRPRV-EESGSKKEGKRQGPKEPPR- 543
H KE E+ +E K + + +K+ + +E G+K+ G + E PR
Sbjct: 506 HHKEKIKQAKEAVKENLKKFSDSV-KSTFRHFKDTTKNIFDEKGNKRFGATKEAAEKPRT 564
Query: 544 -------------------KSGSFHSSGEKQKQPRWREGTKDSHDPLPSWAELLRPKYRA 584
+ + + G K+K ++E K+++ S R +
Sbjct: 565 VFSDYLHPQYKAPTENHHNRGPTMQNDGRKEKPVHFKEFRKNTNSKKCSPGHDCRENSHS 624
Query: 585 -PQGCSGVDECARQEGLTFFGTELAPVRQQELASLLRTYLARLPWAGQLTKELPLSPAFF 643
+ CSGV +CA+QE ++ F T + P+R E +++ Y+ + EL F
Sbjct: 625 FRKACSGVFDCAQQESMSLFNTVVNPIRMDEFRQIIQRYMLKELDTFCHWNELDQFINKF 684
Query: 644 GEDGIFRHDRLRFRDFVDALEDSLEEVAVQQTGDDDEVDDFEDFIFSHFFG 694
+G+F HD+ F DFV+ ++D L + + +D + +++I+ HFFG
Sbjct: 685 FLNGVFIHDQKLFTDFVNDVKDYLRNMKEYEVDNDGVFEKLDEYIYRHFFG 735
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 55.1 bits (131), Expect = 2e-07
Identities = 84/351 (23%), Positives = 147/351 (41%), Gaps = 45/351 (12%)
Query: 227 EVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQ 286
E+ R + D E+ E + L+E+LQ S L N+ L KL E + L Q
Sbjct: 269 ELYRNTITDEELKE----KNAKLQEKLQLVESEKSEIQL-NVKELKRKL--ERAKLLLPQ 321
Query: 287 AQLQAQKE----ELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLE 342
QLQA+ + ELQS+ + + EEN QQ E E ++Q+ ++Q E
Sbjct: 322 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 381
Query: 343 ADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQR 402
+ +R + ++ IREQ + + E +++E++ + + + ++ E+ R
Sbjct: 382 -EKIR-------------EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 427
Query: 403 RLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQ 462
R Q+++ ++ R E +K Q E + +K W Q
Sbjct: 428 R-----QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 482
Query: 463 KSHFQNSRE--WSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQE---DREPAGRW 517
+ + E +EK W Q ++ E K ++EE +E+++ W +E ++E R
Sbjct: 483 EEKIREQEEKIREQEEKMW-RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 541
Query: 518 KEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEK---QKQPRWREGTK 565
KE EE K+E K R+ H EK Q++ WR+ K
Sbjct: 542 KEKIHEQEEKIRKQEEKMW------RQEEKMHDQEEKIREQEEKVWRQEEK 586
Score = 47.4 bits (111), Expect = 5e-05
Identities = 55/307 (17%), Positives = 132/307 (42%), Gaps = 25/307 (8%)
Query: 273 DKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQ 332
+K+ ++ + IR + +++ Q+E + + + EE + +++ E E +++
Sbjct: 382 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 441
Query: 333 QLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQ 392
+L ++ E + +R + Q ++ IREQ R QE E +Q+E++ + +
Sbjct: 442 ELEEKMH--EQEKIREQE-------EKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEE 491
Query: 393 ALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKL--QGLENWGQDP 450
+R++ E+ R + + E+ ++ R + E R +++ Q + Q+
Sbjct: 492 KIREQEEKMWRQEEKIHEQ-EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEE 550
Query: 451 GVSANASKAWHQKSHFQNSRE---------WSGKEKWWD-GQRDRKAEHWKHKKEESGRE 500
+ K W Q+ + E W +EK + ++ R+ E ++EE +E
Sbjct: 551 KIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQE 610
Query: 501 RKKNWGGQEDR--EPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQP 558
+++ G QE++ E + +E ++ K + + +E K ++Q++
Sbjct: 611 QEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 670
Query: 559 RWREGTK 565
W + K
Sbjct: 671 MWEQEEK 677
Score = 35.4 bits (80), Expect = 0.19
Identities = 25/131 (19%), Positives = 63/131 (48%)
Query: 273 DKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQ 332
+K+ + + IR + ++ Q+E+++ + + EE+ + Q+ E E ++
Sbjct: 564 EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 623
Query: 333 QLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQ 392
+ ++Q E R + + + + ++ IREQ QE E +Q+E++ + +
Sbjct: 624 EQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 683
Query: 393 ALRQELERQRR 403
++++ E+ RR
Sbjct: 684 KMQEQEEKMRR 694
Score = 33.5 bits (75), Expect = 0.72
Identities = 29/185 (15%), Positives = 84/185 (45%), Gaps = 1/185 (0%)
Query: 217 LSESETGPMEEVERQVLPDPEVLEAVGDRQDGLR-EQLQAPVPPDSVPSLQNMGLLLDKL 275
+ E E E+ E+ + ++ E R++ R EQ + + + + + +K+
Sbjct: 486 IREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKI 545
Query: 276 AKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLR 335
++ + IR + ++ Q+E++ + + EE+ + +++ E R E ++++
Sbjct: 546 HEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE 605
Query: 336 ARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALR 395
Q E + +C + + ++ +R Q + +E E +Q+E++ + + ++
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 665
Query: 396 QELER 400
++ E+
Sbjct: 666 EQEEK 670
Score = 33.5 bits (75), Expect = 0.72
Identities = 24/130 (18%), Positives = 62/130 (47%)
Query: 273 DKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQ 332
+K+ ++ + IR + +++ Q+E Q + EE+ + +Q+ E R E +++
Sbjct: 585 EKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR 644
Query: 333 QLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQ 392
+ +++ E + + + + ++ + EQ + QE E +Q+E++ +
Sbjct: 645 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 704
Query: 393 ALRQELERQR 402
LRQ+ E+ +
Sbjct: 705 RLRQQEEKMQ 714
Score = 32.0 bits (71), Expect = 2.1
Identities = 28/162 (17%), Positives = 75/162 (46%), Gaps = 12/162 (7%)
Query: 240 EAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEEL--- 296
E + D+++ +REQ + + Q +K+ ++ + IR + Q Q+E++
Sbjct: 564 EKMHDQEEKIREQEEKVWRQEEKIREQE-----EKIREQEEKIREQEEMTQEQEEKMGEQ 618
Query: 297 -QSLMHQPKGLEEENAQLRGA---LQQGEAFQRALESELQQLRARLQGLEADCVRGPDGV 352
+ + Q + ++E+ ++R +++ E R E ++++ +Q E + +
Sbjct: 619 EEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 678
Query: 353 CLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQAL 394
C + + ++ +R Q + E E+ +Q+E+++ + L
Sbjct: 679 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 54.3 bits (129), Expect = 4e-07
Identities = 80/349 (22%), Positives = 150/349 (42%), Gaps = 42/349 (12%)
Query: 227 EVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQ 286
E+ R + D E+ E + L+E+LQ S L N+ L KL E + L Q
Sbjct: 208 ELYRNTITDEELKE----KNAKLQEKLQLVESEKSEIQL-NVKELKRKL--ERAKLLLPQ 260
Query: 287 AQLQAQKE----ELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLE 342
QLQA+ + ELQS+ + + EEN QQ E E ++Q+ ++Q E
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Query: 343 ADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQR 402
+ +R + ++ IREQ + + E +++E++ + + + ++ E+ R
Sbjct: 321 -EKIR-------------EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
Query: 403 RLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQ 462
R L + + E +++ + E +K Q E + +K W Q
Sbjct: 367 R-LEEMMWEKEEKIRELEEKMHEQEKIRE----QEEKRQEEEKIREQEKRQEQEAKMWRQ 421
Query: 463 KSHFQNSRE--WSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQED-REPAGRWKE 519
+ + E ++K W Q ++ E K ++EE +E+++ W +E RE W++
Sbjct: 422 EEKIREQEEKIREQEKKMW-RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 480
Query: 520 GRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEK---QKQPRWREGTK 565
+E ++E R+ ++ R+ H EK Q++ WR+ K
Sbjct: 481 -----KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEK 524
Score = 41.2 bits (95), Expect = 0.003
Identities = 51/301 (16%), Positives = 128/301 (42%), Gaps = 21/301 (6%)
Query: 266 QNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQR 325
+ M L + + ++ + IR L+ ++ Q++ + + K EEE + + Q+ EA
Sbjct: 363 EKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ---EEKRQEEEKIREQEKRQEQEAKMW 419
Query: 326 ALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKE 385
E ++++ +++ E R + + + IRE+ R+++ E+ ++K
Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKI--------HEQEKIREEEKRQEQEEMWRQEEKI 471
Query: 386 QLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLEN 445
+ + E ++++ Q + +++ E+ + + + E ++ ++ + +
Sbjct: 472 REQEEIWRQKEKMHEQEK----IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527
Query: 446 WGQDPGVSANASKAWHQKSHFQNSREWSGK--EKWWDGQRDRKAEHWKHKKEESGRERKK 503
Q+ + K Q+ Q E G+ EK + ++ R+ E ++EE RE+K+
Sbjct: 528 --QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKE 585
Query: 504 NWGGQEDR--EPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWR 561
QE++ E + +E ++E K + + E K +Q++ W
Sbjct: 586 KIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 645
Query: 562 E 562
+
Sbjct: 646 Q 646
Score = 36.6 bits (83), Expect = 0.085
Identities = 32/164 (19%), Positives = 77/164 (46%), Gaps = 27/164 (16%)
Query: 240 EAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSL 299
E + D+++ +REQ + M +K+ ++ + IR + +++ Q+E +Q
Sbjct: 502 EKMHDQEEKIREQEE------------KMWRQEEKIREQEEKIREQEEKIREQEEMMQE- 548
Query: 300 MHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRG 359
+ G +EE Q + +++ E R E ++++ + +++ E
Sbjct: 549 QEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIW------------- 595
Query: 360 PQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRR 403
+ ++ IREQ QE E +Q+E++ + + ++++ E+ RR
Sbjct: 596 -EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 638
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 53.9 bits (128), Expect = 5e-07
Identities = 86/364 (23%), Positives = 146/364 (40%), Gaps = 57/364 (15%)
Query: 227 EVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQ 286
E+ R + D E+ E + L+E+LQ S L N+ L KL E + L Q
Sbjct: 208 ELYRNTITDEELKE----KNAKLQEKLQLVESEKSEIQL-NVKELKRKL--ERAKLLLPQ 260
Query: 287 AQLQAQKE----ELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLE 342
QLQA+ + ELQS+ + + EEN QQ E E ++Q+ ++Q
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ--- 317
Query: 343 ADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQL-EAEAQALRQE---- 397
+ ++ IREQ + +E E +Q+E + E E + RQE
Sbjct: 318 ------------------EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 359
Query: 398 -----LERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGH------RLAQKLQGLENW 446
+ RQ ++ ++ + R + + L E H +K Q E
Sbjct: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 419
Query: 447 GQDPGVSANASKAWHQKSHFQNSRE--WSGKEKWWDGQRDRKAEHWKHKKEESGRERKKN 504
+ +K W Q+ + E ++K W Q ++ E K ++EE +E+++
Sbjct: 420 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW-RQEEKIHEQEKIREEEKRQEQEEM 478
Query: 505 WGGQE---DREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWR 561
W +E ++E R KE EE K+E K +E R+ +Q++ WR
Sbjct: 479 WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQ---EEKIREQEEKMWR 535
Query: 562 EGTK 565
+ K
Sbjct: 536 QEEK 539
Score = 46.2 bits (108), Expect = 1e-04
Identities = 41/241 (17%), Positives = 107/241 (44%), Gaps = 10/241 (4%)
Query: 273 DKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQ 332
+K+ ++ + IR + ++ Q+E+++ + + EE+ + +++ E R E +
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
Query: 333 QLRA----RLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLE 388
Q + + Q E R + + + + ++ IREQ + QE E KQ+E++
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
Query: 389 AEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQ 448
+ + ++++ E+ R +++ E + + + + E ++ ++ + + W Q
Sbjct: 616 EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM--WRQ 673
Query: 449 DPGVSANASKAWHQKSHFQNSREW--SGKEKWWDGQRD--RKAEHWKHKKEESGRERKKN 504
+ + K Q+ + E +EK W+ + + E + ++E+ R+ +K
Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733
Query: 505 W 505
W
Sbjct: 734 W 734
Score = 43.5 bits (101), Expect = 7e-04
Identities = 59/344 (17%), Positives = 144/344 (41%), Gaps = 34/344 (9%)
Query: 226 EEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLL 285
E++ RQ E E + ++++ +REQ + + + +++ E ++
Sbjct: 300 EKMWRQEEKIQEWEEKIQEQEEKIREQ------EEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 286 QAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADC 345
Q ++ +KEE + Q + + E+ ++R + E E ++++L ++ E +
Sbjct: 354 QEEMMWEKEE--KMRRQEEMMWEKEEKMR----RQEEMMWEKEEKIRELEEKMH--EQEK 405
Query: 346 VRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLL 405
+R + Q ++ IREQ R QE E +Q+E++ + + +R++ ++ R
Sbjct: 406 IREQE-------EKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 457
Query: 406 GSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKL--QGLENWGQDPGVSANASKAWHQK 463
+ + E+ ++ R + E +++ Q + Q+ + K W Q+
Sbjct: 458 EKIHEQ-EKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516
Query: 464 SHFQNSREW--SGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGR 521
+ E +EK W + + + ++EE E++K W ++ +E +
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 522 PRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTK 565
++ E K + + +E K ++Q++ W++ K
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKR-------QEQEEKMWKQEEK 613
Score = 41.2 bits (95), Expect = 0.003
Identities = 55/279 (19%), Positives = 115/279 (41%), Gaps = 16/279 (5%)
Query: 272 LDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESEL 331
L++ E + IR + + +++E + + Q K E+E R + E ++ E E
Sbjct: 396 LEEKMHEQEKIR----EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451
Query: 332 QQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKA-----IREQGPREQEPELSFLKQKEQ 386
+ R + E + +R + Q +K I Q + E E KQ+E+
Sbjct: 452 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEK 511
Query: 387 LEAEAQALRQELERQRRLLGSV--QQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLE 444
+ + + +R++ E+ R + Q++ R ++ R + ++ ++ Q +
Sbjct: 512 VWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDK 571
Query: 445 NWGQDPGVSANASKAWHQKSHF---QNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRER 501
W Q+ + K W Q+ + R+ ++ W ++ R+ E ++EE RE+
Sbjct: 572 MWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ 631
Query: 502 KKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKE 540
++ QE+ K G EE ++E K Q +E
Sbjct: 632 EEKIREQEEMTQEQEEKMGEQ--EEKMCEQEEKMQEQEE 668
Score = 30.8 bits (68), Expect = 4.7
Identities = 23/130 (17%), Positives = 61/130 (46%)
Query: 273 DKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQ 332
+K+ ++ + IR + +++ Q+E Q + EE+ + +Q+ E E +++
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 333 QLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQ 392
+ +++ E + + + + ++ + EQ + QE E +Q+E++ +
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 393 ALRQELERQR 402
LRQ+ E+ +
Sbjct: 739 RLRQQEEKMQ 748
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 53.9 bits (128), Expect = 5e-07
Identities = 74/389 (19%), Positives = 159/389 (40%), Gaps = 50/389 (12%)
Query: 225 MEEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRL 284
+ E E ++ ++ E V ++ + Q Q D +Q + ++ K ++
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEET 465
Query: 285 LQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEAD 344
++ Q + +++ +++ Q EE+ Q + +Q E + E E Q + + +
Sbjct: 466 MREQEEKMQKQEENMWEQ----EEKEWQQQRLPEQKE---KLWEQEKMQEQEEKIWEQEE 518
Query: 345 CVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRL 404
+R + + Q K R++ REQE ++ +Q+E++ + Q + + ER +
Sbjct: 519 KIRDQEEMW------GQEKKMWRQEKMREQEDQM--WEQEEKMRDQEQKMWDQEERMEKK 570
Query: 405 LGSVQQ---DLERSLQDASRGDPAHAGLAE---LGHRLAQKLQGLEN---------WGQD 449
++ D E +++ R + E + +K+Q E W Q+
Sbjct: 571 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630
Query: 450 PGVSANASKAWHQKSHFQNSREWSGKEKWWDGQR--DRKAEHWKHKK---EESGRERKKN 504
+ K W Q+ + W +EK W+ QR ++K + W+H+K +E +E+++
Sbjct: 631 EKMQEQEEKMWEQE-----EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685
Query: 505 WGGQEDREPAGR------WKEGRPRVEESGSKKEGKRQGPKEPPR----KSGSFHSSGEK 554
QE E + W + + R EES ++E K + +E R K ++
Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745
Query: 555 QKQPRWREGTKDSHDPLPSWAELLRPKYR 583
Q++ W + K W + P+ +
Sbjct: 746 QEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774
Score = 53.5 bits (127), Expect = 7e-07
Identities = 61/321 (19%), Positives = 133/321 (41%), Gaps = 28/321 (8%)
Query: 273 DKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQ 332
+K +E +++R + Q+Q Q+E++ + + EE+ + L + E R E +++
Sbjct: 334 EKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393
Query: 333 QLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPEL----SFLKQKEQLE 388
R+ + + + Q +K E+ +EQE + ++++E++
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR 453
Query: 389 AEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQ 448
+ +R+E E R +Q+ E ++ + + L E +L W Q
Sbjct: 454 EREKKMREEEETMREQEEKMQKQ-EENMWEQEEKEWQQQRLPEQKEKL---------WEQ 503
Query: 449 DPGVSANASKAWHQKSHFQNSRE-WSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGG 507
+ + K W Q+ ++ E W ++K W ++ R+ E ++EE R++++
Sbjct: 504 EK-MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 562
Query: 508 QEDR-------EPAGRW-KEGRPRVEESGSKKEGKRQGPKEPPR----KSGSFHSSGEKQ 555
QE+R + W +E + R EE ++E K + +E R K ++Q
Sbjct: 563 QEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 622
Query: 556 KQPRWREGTKDSHDPLPSWAE 576
++ W + K W +
Sbjct: 623 EEKMWEQEEKMQEQEEKMWEQ 643
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/315 (18%), Positives = 135/315 (42%), Gaps = 31/315 (9%)
Query: 273 DKLAKENQDIRLLQAQLQAQKEEL-----------QSLMHQPKGLEEENAQLRGALQQ-- 319
++L ++ + IR + ++ Q+E L + + Q K L E+ +LR ++
Sbjct: 279 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 338
Query: 320 GEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGP--REQEPE 377
+ R E ++Q+ ++ E + + R + +K +REQ R+QE
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398
Query: 378 L----SFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELG 433
+ L++KE+ E + + +++E+ R Q+ E+ +D + E
Sbjct: 399 MWEQDERLREKEERMREQEKMWEQVEKMRE--EKKMQEQEKKTRDQEEKMQEEERIRERE 456
Query: 434 HRLAQKLQGLENWGQDPGVSANASKAWHQ-KSHFQNSREWSGKEKWWDGQRDRKAEHWKH 492
++ ++ + + Q+ + W Q + +Q R KEK W+ ++ ++ E
Sbjct: 457 KKMREEEETMRE--QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 514
Query: 493 KKEESGRERKKNWGGQEDREPAGRWKEGRPRVEES--GSKKEGKRQGPKEPPRKSGSFHS 550
++EE R++++ WG ++ W++ + R +E ++E R ++ +
Sbjct: 515 EQEEKIRDQEEMWGQEKK-----MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEK 569
Query: 551 SGEKQKQPRWREGTK 565
++Q++ W + K
Sbjct: 570 KTQEQEKKTWDQEEK 584
Score = 46.2 bits (108), Expect = 1e-04
Identities = 60/302 (19%), Positives = 128/302 (42%), Gaps = 15/302 (4%)
Query: 278 ENQDIRLLQAQLQAQKEELQSLMHQPKG--LEEENAQLRGALQQGEAFQRALESELQQLR 335
E +I+L +L+ + E + L+ Q + L+EE + L++ E R E ++ +
Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 299
Query: 336 ARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALR 395
RL+ E + + + +K +REQ +E E +QKE E E Q
Sbjct: 300 ERLREQEGKMREQEEKMW-------RQEKRLREQEKELREQEKELREQKELREQEEQMQE 352
Query: 396 QELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSAN 455
QE E+ +++ E+ + R + E ++ + + + W QD +
Sbjct: 353 QE-EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM--WEQDERLREK 409
Query: 456 ASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAG 515
+ Q+ ++ + ++K + ++ + + K ++EE RER+K +E+ E
Sbjct: 410 EERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKM--REEEETMR 467
Query: 516 RWKEGRPRVEESGSKKEGKR-QGPKEPPRKSGSFHSSGEKQKQPRWREGTKDSHDPLPSW 574
+E + EE+ ++E K Q + P +K + ++++ + E + D W
Sbjct: 468 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 527
Query: 575 AE 576
+
Sbjct: 528 GQ 529
Score = 44.7 bits (104), Expect = 3e-04
Identities = 57/292 (19%), Positives = 129/292 (44%), Gaps = 38/292 (13%)
Query: 226 EEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLL 285
E+++ Q E E + ++++ + EQ + P + + + M +K+ ++ + I
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ-EKMQEQEEKIWEQ 689
Query: 286 QAQLQAQKEELQSLMHQPKGLEEENAQLRGA-LQQGEAFQRALESELQQLRARLQGLEAD 344
+ + +E+ + Q K EEE+ + R +++ E R E ++Q+ ++Q E +
Sbjct: 690 EKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEE 749
Query: 345 CVRGPDGVCLSGGRGPQGDKAIREQGPREQEPEL---SFLKQKEQLEAEAQALRQELERQ 401
+ + Q +K +Q EQ+ +L ++++E++ + + +R + E+
Sbjct: 750 MWEQEEKMW------EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKM 803
Query: 402 RRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLEN--WGQDPGVSANASKA 459
R Q++ R ++ RG +K+ G E WGQ+ + K
Sbjct: 804 RG-----QEEKMRGQEEKMRGQE-------------EKMWGQEEKMWGQEEKMWGQEEKM 845
Query: 460 WHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDR 511
W Q+ + + G+E ++ R+ E +EE RE+++ GQE++
Sbjct: 846 WGQEEKMEEKMQ--GQE-----EKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 37.7 bits (86), Expect = 0.038
Identities = 54/268 (20%), Positives = 118/268 (44%), Gaps = 25/268 (9%)
Query: 290 QAQKEELQSLMHQPKGLEEENAQLRGA-LQQGEAFQRALESELQQLRARLQGLEADCVRG 348
+ Q++E ++ + K EEE + R +++ E R E ++Q+ ++Q E
Sbjct: 570 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQ 629
Query: 349 PDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQL-EAEAQALRQELERQRRLLGS 407
+ + + + ++ + EQ + E + +QKE+L E E +++++ Q +
Sbjct: 630 EEKMQEQEEKMWEQEEKMWEQEEKMWEQQ-RLPEQKEKLWEHEKMQEQEKMQEQEEKIWE 688
Query: 408 VQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQ 467
Q+ +E+ Q+ + + E ++ + E ++ + K Q+ Q
Sbjct: 689 -QEKMEKKTQEQEKKTWDQEKMREEESMREREKKMRE---EEEMMREQEEKMQEQEEKMQ 744
Query: 468 NSRE--WSGKEKWWDGQR---------DRKAEHWKHKKEESGRERKKNWGGQE---DREP 513
E W +EK W+ + ++K + W+H+K + E++K W +E D+E
Sbjct: 745 EQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ---EQEKIWEQEEKMRDQEE 801
Query: 514 AGRWKEGRPRVEESGSK-KEGKRQGPKE 540
R +E + R +E + +E K G +E
Sbjct: 802 KMRGQEEKMRGQEEKMRGQEEKMWGQEE 829
Score = 36.2 bits (82), Expect = 0.11
Identities = 62/327 (18%), Positives = 138/327 (42%), Gaps = 39/327 (11%)
Query: 225 MEEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRL 284
M E E+++ + E++ ++ E++Q + M +K+ ++ + +
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQE--------EKMWEQEEKMQEQEEKMWE 642
Query: 285 LQAQLQAQKEEL---QSLMHQPKGL-EEENAQLRGALQQGEAF---QRALESELQQLRAR 337
+ ++ Q+E++ Q L Q + L E E Q + +Q+ E Q +E + Q+ +
Sbjct: 643 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Query: 338 LQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQE 397
E +R + + + + ++ +REQ + QE E +Q+E++ + + + ++
Sbjct: 703 TWDQEK--MREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQ 760
Query: 398 LER---QRRLLGSVQQDLERS-LQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVS 453
E+ Q+RL ++ E +Q+ + + + +K++G E
Sbjct: 761 EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQ----EEKMRGQEE-------- 808
Query: 454 ANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREP 513
+ +K Q + W +EK W GQ ++ W +++ G+E K Q E
Sbjct: 809 --KMRGQEEKMRGQEEKMWGQEEKMW-GQEEKM---WGQEEKMWGQEEKMEEKMQGQEEK 862
Query: 514 AGRWKEGRPRVEESGSKKEGKRQGPKE 540
+E EE ++E K +G +E
Sbjct: 863 MREQEEKMRGQEEKMREQEEKMRGQEE 889
Score = 31.2 bits (69), Expect = 3.6
Identities = 51/334 (15%), Positives = 142/334 (42%), Gaps = 19/334 (5%)
Query: 240 EAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEEL--- 296
E + ++++ +Q + P + + + M +K+ ++ + IR Q ++ Q++++
Sbjct: 478 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD-QEEMWGQEKKMWRQ 536
Query: 297 QSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSG 356
+ + Q + E+ ++R Q+ + +E + Q+ + E + +R + +
Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQE-EKMREEERMRERE 595
Query: 357 GRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELER---QRRLLGSVQQDL- 412
+ + ++ +REQ + QE E +Q+E++ + + ++++ E+ Q + ++ +
Sbjct: 596 KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Query: 413 -ERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQK------SH 465
++ L + H + E Q+ + E + K W Q+ S
Sbjct: 656 EQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM 715
Query: 466 FQNSREWSGKEKWWDGQRDR---KAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRP 522
+ ++ +E+ Q ++ + E + ++EE + +K W +E R E +
Sbjct: 716 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKE 775
Query: 523 RVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQK 556
++ E +E ++ +E + G+++K
Sbjct: 776 KLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEK 809
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 52.8 bits (125), Expect = 1e-06
Identities = 79/391 (20%), Positives = 157/391 (40%), Gaps = 66/391 (16%)
Query: 217 LSESETGPMEEVERQVLPDPEVLEAVGDRQDGLR------EQLQAPVPPDSVPSLQNMGL 270
L++ P E+ R + D E+ E + Q+ LR ++Q V D L+ L
Sbjct: 195 LTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVK-DLKRKLERAQL 253
Query: 271 LL---------DKLAKENQDIRL-LQAQL----------QAQKEEL----QSLMHQPKGL 306
LL D+L KE Q + LQAQ+ Q Q+E++ + + Q + +
Sbjct: 254 LLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKM 313
Query: 307 EEENAQLRGA---LQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGD 363
E+ ++R + + E E ++++ ++ E + + + + +
Sbjct: 314 CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQE 373
Query: 364 KAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGD 423
+ IREQ + QE E +Q+E++ + + ++++ RQ + + + + ++ R +
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 424 PAHAGLAELGHRLAQKLQGLEN----------------WGQDPGVSANASKAWHQ----- 462
L E+ +KL+ +E Q+ + K W Q
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 463 ---KSHFQNSREWSGKEKWWDGQRDRKAEHWK-HKKEESGRERKKNWGGQEDR--EPAGR 516
K Q + W +EK W+ + + + K ++EE RE++ QE++ E R
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 517 WKEGRPRVEESGSKKE-----GKRQGPKEPP 542
+E R+ + G K E G+ G + P
Sbjct: 554 LQELEERLGKLGQKAELLGGAGRESGSQRLP 584
Score = 47.4 bits (111), Expect = 5e-05
Identities = 55/226 (24%), Positives = 100/226 (44%), Gaps = 26/226 (11%)
Query: 363 DKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLE-----RSLQ 417
D+ ++E+ QE +K +++ + L+++LER + LL Q +E + LQ
Sbjct: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ 272
Query: 418 DASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQ--KSHFQNSREWSGK 475
S A EL + L Q+ Q + W Q+ + K Q K Q + W +
Sbjct: 273 SVSAKLQAQVEENELWNLLNQQ-QEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
Query: 476 EKWWDGQ---RDRKAEHWKHKK-----EESGRERKKNWGGQEDR-----EPAGRWKEGRP 522
EK + + R+++ + W+ ++ EE RE+++ QE++ E +E
Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMW 391
Query: 523 RVEESGSKKEGKRQGPKEPPRKSGSFHSSGEK---QKQPRWREGTK 565
R EE ++E KRQ ++ R+ EK Q++ WR+ K
Sbjct: 392 RQEEKIREQEEKRQ--EKMWRQEKKMREQDEKIREQEEEMWRQEEK 435
Score = 37.0 bits (84), Expect = 0.065
Identities = 54/315 (17%), Positives = 133/315 (42%), Gaps = 34/315 (10%)
Query: 268 MGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRAL 327
MG ++KL KE A EL + L+E+NA+L+ L+ E+ + +
Sbjct: 188 MGTYIEKLTKERD----------APSLELYRNTITDEELKEKNAELQEKLRLVESEKSEI 237
Query: 328 ESELQQLRARLQGLEADCVRGPDGVCLSGGR-GPQGDKAIREQGPREQEPELSFL---KQ 383
+ ++ L+ +L+ A + + + R G + + + +E EL L +Q
Sbjct: 238 QLNVKDLKRKLE--RAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQ 295
Query: 384 KEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGL 443
+E++ + + ++++ E+ +++ E+ + + + E ++ ++ + +
Sbjct: 296 EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKI 355
Query: 444 ENWGQDPGVSANASKAWHQKSHF--QNSREWSGKEKWW-------DGQRDRKAEHWKHKK 494
Q+ + K W Q+ Q+ + +E+ W + + R+ + W+ +K
Sbjct: 356 RE--QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413
Query: 495 -----EESGRERKKNWGGQED--REPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGS 547
+E RE+++ QE+ RE ++ ++ E K + + + +E K
Sbjct: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473
Query: 548 FHSSGEKQKQPRWRE 562
++Q++ WR+
Sbjct: 474 QEEKIQEQEEKTWRQ 488
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 52.8 bits (125), Expect = 1e-06
Identities = 54/292 (18%), Positives = 131/292 (44%), Gaps = 13/292 (4%)
Query: 277 KENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRA 336
K ++ I L + A EL + L+++NA+L+ L+ E+ + ++ +++L+
Sbjct: 156 KADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKR 215
Query: 337 RLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQ 396
+L+ + + + ++ +REQ + ++ E +Q+E+L + +R+
Sbjct: 216 KLERAKFLLPQVQTNTLQE--EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE 273
Query: 397 ELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANA 456
+ E+ RR +++ E+ L++ + L E ++ ++ + + W Q+ +
Sbjct: 274 QEEKMRRQEKRLREQ-EKELREQEKELREQKKLREQEEQMQEQEEKM--WEQEEKMREQE 330
Query: 457 SKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWK-----HKKEESGRERKKNWGGQEDR 511
K W Q+ + +++ RD++ W+ +KEE RE++K W +E
Sbjct: 331 EKMWRQEERLWEQEKQMREQE--QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKM 388
Query: 512 EPAGRWKEGRPRV-EESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWRE 562
+ R +E ++ EE + +E + + K+ ++Q+ P +E
Sbjct: 389 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440
Score = 52.8 bits (125), Expect = 1e-06
Identities = 64/328 (19%), Positives = 138/328 (42%), Gaps = 36/328 (10%)
Query: 273 DKLAKENQDIRLLQAQLQAQKEEL-----------QSLMHQPKGLEEENAQLRGALQQ-- 319
++L ++ + IR + ++ Q+E L + + Q K L E+ +LR ++
Sbjct: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
Query: 320 GEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELS 379
+ R E ++Q+ ++ E + + R + +K +REQ + ++ E
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Query: 380 FLKQKEQLEAEAQALR------------QELERQRRLLGSVQQDLERSLQDASRGDPAHA 427
+Q E+L + + +R QE ER R ++++ E + +
Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420
Query: 428 GLAELGHRLAQKLQGLEN----WGQDPGVSANASKAWHQKSHFQNSRE-WSGKEKWWDGQ 482
+ E + Q+ + E W Q+ + K W Q+ ++ E W ++K W +
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEK-MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 479
Query: 483 RDRKAEHWKHKKEESGRERKKNWGGQEDR--EPAGRWKEGRPRVEES---GSKKEGKRQG 537
+ R+ E ++EE R++++ QE+R E R +E R+ E ++E R+
Sbjct: 480 KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREE 539
Query: 538 PKEPPRKSGSFHSSGEKQKQPRWREGTK 565
K ++ ++ + +++ R RE K
Sbjct: 540 KKTQEQEKKTWDQEEKMREEERMREREK 567
Score = 47.0 bits (110), Expect = 6e-05
Identities = 57/320 (17%), Positives = 139/320 (43%), Gaps = 29/320 (9%)
Query: 240 EAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSL 299
E + ++++ +R+Q + + + M D++ ++ + +R + ++ Q+E +
Sbjct: 453 EKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM--- 509
Query: 300 MHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRG 359
Q + L E+ ++R + + ++ E + Q + + + + +R + + +
Sbjct: 510 WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM 569
Query: 360 PQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSV-QQDLERSLQD 418
+ ++ +REQ + QE E +Q+E++ + + ++++ E+ + +Q+ E +Q+
Sbjct: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE 629
Query: 419 ASRGDPAHAGLAELGHRLAQKLQGLEN--WGQDPGVSANASKAWHQKSHFQNSRE-WSGK 475
E+ +K+Q E W Q+ + K Q+ Q E +
Sbjct: 630 QE----------EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679
Query: 476 EKWWDGQRDRKAEH-----------WKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRV 524
E+ GQ ++ E W +++ G+E K WG +E RE R ++ + ++
Sbjct: 680 EEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKM-WGQEEMREKEERIRDQKEKM 738
Query: 525 EESGSKKEGKRQGPKEPPRK 544
+E + E + P PP K
Sbjct: 739 QERLPEHEERCSEPCLPPSK 758
Score = 42.7 bits (99), Expect = 0.001
Identities = 60/365 (16%), Positives = 148/365 (40%), Gaps = 16/365 (4%)
Query: 219 ESETGPMEEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKE 278
E E +++ Q E E + ++++ +REQ + + Q + +
Sbjct: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 279 NQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARL 338
+Q+ R+ + + +++E + + +EE Q +++ E R E +++ ++
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM 415
Query: 339 QGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQEL 398
Q E + + Q +K ++ +EQE ++ ++K + + E +++
Sbjct: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 475
Query: 399 ERQRRLLGSVQQ--DLERSLQDASRGD-PAHAGLAELGHRLAQKLQGLEN----WGQDPG 451
RQ ++ Q + E ++D + + E RL +K + + W Q+
Sbjct: 476 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEK 535
Query: 452 VSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDR 511
+ +K+ Q + W +EK + +R R+ E ++EE RE+++ QE++
Sbjct: 536 MREE------KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
Query: 512 EPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDSHDPL 571
R +E + +E +++ ++ +E ++Q++ W + K
Sbjct: 590 M---REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646
Query: 572 PSWAE 576
W +
Sbjct: 647 KMWEQ 651
Score = 42.4 bits (98), Expect = 0.002
Identities = 64/373 (17%), Positives = 156/373 (41%), Gaps = 53/373 (14%)
Query: 225 MEEVERQVLPDPEVL----EAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQ 280
M E E+++ E + E + ++++ +REQ + + + + + K+ +E +
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEE 406
Query: 281 DIRLLQAQLQAQKE---ELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRAR 337
+R + ++Q Q+E E + Q + L E+ +L + E ++ E E +++R
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE-EKIR-- 463
Query: 338 LQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQE 397
+ + + G + + + + + EQ + ++ E Q+E++ + + LR++
Sbjct: 464 ----DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519
Query: 398 LERQRRLLGSVQQ------------------DLERSLQDASRGDPAHAGLAELGHRLAQK 439
ER R QQ D E +++ R + E + ++
Sbjct: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 579
Query: 440 LQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGR 499
+ ++ Q+ + K W Q+ Q +EK W +++ + W+ ++E+ +
Sbjct: 580 EEKMQE--QEEKMREQEEKMWEQEEKMQEQ-----EEKMW----EQEEKMWEQEEEDKMQ 628
Query: 500 ERKKNWGGQEDR---------EPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRK-SGSFH 549
E+++ QE++ E + +E ++ E K +G+ + +E K G
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
Query: 550 SSGEKQKQPRWRE 562
E++++ R +E
Sbjct: 689 KMREQEEKMRGQE 701
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 52.8 bits (125), Expect = 1e-06
Identities = 71/320 (22%), Positives = 133/320 (41%), Gaps = 42/320 (13%)
Query: 286 QAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADC 345
+A++QA+ + ++ +EEE +R L+ E + E ELQ LRAR + EA
Sbjct: 1430 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1489
Query: 346 VRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEA-----------QAL 394
+ + + + ++++ R+++ E+ L + + EAEA + L
Sbjct: 1490 RQAQE-------EAERLRRQVQDESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEEL 1541
Query: 395 RQELERQRRLLGSVQQDLERSLQDA--SRGDPAHAGLAELGHRLAQKLQGLENWGQDPGV 452
R + E R L + + R +Q A + A A L A+K LE Q+ V
Sbjct: 1542 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1601
Query: 453 SA-----NASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGG 507
+ A + Q++ + +RE + +R+ E W+ K E+ R R +
Sbjct: 1602 AVAQLREEAERRAQQQAEAERARE----------EAERELERWQLKANEALRLRLQ---- 1647
Query: 508 QEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDS 567
E+ + ++ +++E +R+G E + E +KQ + EGT +
Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT--A 1705
Query: 568 HDPLPSWAELLRPKYRAPQG 587
L + EL+R + QG
Sbjct: 1706 QQRLAAEQELIRLRAETEQG 1725
Score = 48.9 bits (115), Expect = 2e-05
Identities = 44/157 (28%), Positives = 75/157 (47%), Gaps = 16/157 (10%)
Query: 278 ENQDIR---LLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQL 334
E Q +R L + +L+ Q++ + Q E+E +LR +QGE ++ LE EL +L
Sbjct: 1680 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1739
Query: 335 R-------ARLQGLEADC--VRGPDGVCL-SGGRGPQGDKAIREQGPREQEPELSFLKQK 384
+ + Q LEA+ VR V L S R + ++ E+ + E E ++
Sbjct: 1740 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1799
Query: 385 EQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASR 421
+ A +AL +E +RQR+L ++D R +A R
Sbjct: 1800 AEEAARLRALAEEAKRQRQL---AEEDAARQRAEAER 1833
Score = 47.4 bits (111), Expect = 5e-05
Identities = 63/274 (22%), Positives = 112/274 (40%), Gaps = 21/274 (7%)
Query: 287 AQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCV 346
++L+ QK ++ + Q + +EEE L+ + ++ A + LE EL ++R+ + D +
Sbjct: 1904 SELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE----DTL 1959
Query: 347 RGPDGVCLSGGRGPQGDKAIREQGPREQEPELS-FLKQKEQLEAEAQALRQELER----- 400
R + L R Q A E+ RE E + L +E+ + +A +E+ER
Sbjct: 1960 RSKEQAELEAARQRQL-AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 2018
Query: 401 --QRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLA--QKLQGLENWGQD-----PG 451
RRL +Q+ R LQ A E H A QK Q L+ Q
Sbjct: 2019 EEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQ 2078
Query: 452 VSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQED- 510
+ A A + +R + +E ++ +AE K EE + R + E
Sbjct: 2079 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2138
Query: 511 REPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRK 544
R+ A + R + E++ +++ E +K
Sbjct: 2139 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2172
Score = 39.7 bits (91), Expect = 0.010
Identities = 88/386 (22%), Positives = 146/386 (37%), Gaps = 44/386 (11%)
Query: 286 QAQLQAQKE--ELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEA 343
QA+ QA++E ELQ M +EE + A + +R+++ ELQQLR +
Sbjct: 1381 QAKAQAEREAKELQQRM------QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1434
Query: 344 DCVRGPDGVCLSGGRGPQGDKAIR---EQGPREQ---EPELSFLKQK-EQLEAEAQALRQ 396
R + S R + + +R E R++ E EL L+ + E+ EA+ + ++
Sbjct: 1435 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1494
Query: 397 ELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDP------ 450
E ER RR + Q ++ + + A A A R Q L+ L ++
Sbjct: 1495 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQ 1554
Query: 451 -------GVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEH--WKHKKEESGRER 501
V A S+ S EK +R + EH +EE+ R
Sbjct: 1555 AEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRA 1614
Query: 502 KKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWR 561
++ + RE A R E R + ++ R +E ++ + EKQK+ R
Sbjct: 1615 QQQAEAERAREEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1671
Query: 562 EGTK--DSHDPLPSWAELLRPKYR---------APQGCSGVDECARQEGLTFFGTELAPV 610
E + + + EL + A Q + E R T G + +
Sbjct: 1672 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL 1731
Query: 611 RQQELASLLRTYLARLPWAGQLTKEL 636
++ELA L R A +L EL
Sbjct: 1732 LEEELARLQREAAAATQKRQELEAEL 1757
Score = 37.4 bits (85), Expect = 0.050
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 39/188 (20%)
Query: 260 DSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQ--SLMHQPKGLEEENAQLRGAL 317
+ V +Q + + + + + +R A+L+ +KE+LQ + + Q K E + Q L
Sbjct: 2426 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2485
Query: 318 QQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPE 377
Q+ +A Q++ SE L R + +E +++ +
Sbjct: 2486 QETQALQQSFLSEKDSLLQRERFIE------------------------------QEKAK 2515
Query: 378 LSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGD-PAHAGLAELGHRL 436
L L Q E A+AQ LR+E +RQ++ + +Q L S+++A R A G+ R
Sbjct: 2516 LEQLFQDEV--AKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGV----RRK 2569
Query: 437 AQKLQGLE 444
++LQ LE
Sbjct: 2570 QEELQQLE 2577
Score = 37.0 bits (84), Expect = 0.065
Identities = 67/306 (21%), Positives = 125/306 (40%), Gaps = 39/306 (12%)
Query: 243 GDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQ 302
G++Q L E+ A + ++ + Q L +LAK ++ +L A +EE +S +
Sbjct: 1725 GEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1784
Query: 303 PKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQG 362
K E A L + A RAL E ++ R Q E D R
Sbjct: 1785 SKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---QLAEEDAARQ-------------- 1827
Query: 363 DKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRG 422
R + R +L+ + + +L+ EA+ +E E + L + +D + Q
Sbjct: 1828 ----RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED--EAFQRRRLE 1881
Query: 423 DPAHAGLAELGHRLAQKLQGLEN-WGQDPGVSANASKAWHQ--------KSHFQNSREWS 473
+ A A++ RLAQ + ++ + G+ + + Q K+ F+ +
Sbjct: 1882 EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGK 1941
Query: 474 GKEKWWDGQRDRKAEHWKHKKEESGRE--RKKNWGGQEDREPAGRWKEGRPRVEES-GSK 530
+ + G+ AE KE++ E R++ +E+R R +E RV++S ++
Sbjct: 1942 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER----RRREAEERVQKSLAAE 1997
Query: 531 KEGKRQ 536
+E RQ
Sbjct: 1998 EEAARQ 2003
Score = 36.6 bits (83), Expect = 0.085
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 3/123 (2%)
Query: 277 KENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRA 336
++ Q ++ QA Q+ E SL+ + + +E+E A+L Q A + L E Q+ +
Sbjct: 2480 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ- 2538
Query: 337 RLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQ 396
Q +E + R + + R + ++ +R + Q+ E +Q+E L E Q LR+
Sbjct: 2539 --QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2596
Query: 397 ELE 399
+L+
Sbjct: 2597 QLQ 2599
Score = 35.0 bits (79), Expect = 0.25
Identities = 67/318 (21%), Positives = 122/318 (38%), Gaps = 17/318 (5%)
Query: 230 RQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQL 289
R+ + + E L+ + Q R Q QA + Q + + A++
Sbjct: 2108 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2167
Query: 290 QAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGP 349
+ K+ + + Q +E+E LR L++ + + L+ ELQ+L+A + EA R
Sbjct: 2168 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQ 2225
Query: 350 DGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQ----LEAEAQALRQELERQRRLL 405
L R Q ++ + + E E L+ K+ L+ EA+ ++Q E R L
Sbjct: 2226 VEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-L 2283
Query: 406 GSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSH 465
Q+ R Q A LAE L +K+Q ++ + + A A QK
Sbjct: 2284 SVAAQEAARLRQLAEEDLAQQRALAE--KMLKEKMQAVQ---EATRLKAEAELLQQQKEL 2338
Query: 466 FQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREP--AGRWKEGRPR 523
Q ++K Q+ + + E+ R+R+ + +R + R
Sbjct: 2339 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2398
Query: 524 VEESGS--KKEGKRQGPK 539
EE +K+ + G K
Sbjct: 2399 AEEDAQRFRKQAEEIGEK 2416
Score = 30.4 bits (67), Expect = 6.1
Identities = 47/183 (25%), Positives = 77/183 (42%), Gaps = 21/183 (11%)
Query: 283 RLLQAQLQAQKEELQSLMHQ-PKGLEEEN---AQLRG-----ALQQGEAFQRALESELQQ 333
R +A+LQ+++ Q + L+EE+ AQLR A QQ EA + E+E +
Sbjct: 1572 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1631
Query: 334 LRARLQGLEADCVR-----GPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLE 388
R +L+ EA +R L+ + + + R + E ++Q+E E
Sbjct: 1632 ERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAE 1691
Query: 389 AEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRL-------AQKLQ 441
E + RQ E + + +Q+L R + +G+ L E RL QK Q
Sbjct: 1692 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1751
Query: 442 GLE 444
LE
Sbjct: 1752 ELE 1754
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 52.8 bits (125), Expect = 1e-06
Identities = 71/320 (22%), Positives = 133/320 (41%), Gaps = 42/320 (13%)
Query: 286 QAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADC 345
+A++QA+ + ++ +EEE +R L+ E + E ELQ LRAR + EA
Sbjct: 1434 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1493
Query: 346 VRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEA-----------QAL 394
+ + + + ++++ R+++ E+ L + + EAEA + L
Sbjct: 1494 RQAQE-------EAERLRRQVQDESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEEL 1545
Query: 395 RQELERQRRLLGSVQQDLERSLQDA--SRGDPAHAGLAELGHRLAQKLQGLENWGQDPGV 452
R + E R L + + R +Q A + A A L A+K LE Q+ V
Sbjct: 1546 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1605
Query: 453 SA-----NASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGG 507
+ A + Q++ + +RE + +R+ E W+ K E+ R R +
Sbjct: 1606 AVAQLREEAERRAQQQAEAERARE----------EAERELERWQLKANEALRLRLQ---- 1651
Query: 508 QEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDS 567
E+ + ++ +++E +R+G E + E +KQ + EGT +
Sbjct: 1652 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT--A 1709
Query: 568 HDPLPSWAELLRPKYRAPQG 587
L + EL+R + QG
Sbjct: 1710 QQRLAAEQELIRLRAETEQG 1729
Score = 48.9 bits (115), Expect = 2e-05
Identities = 44/157 (28%), Positives = 75/157 (47%), Gaps = 16/157 (10%)
Query: 278 ENQDIR---LLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQL 334
E Q +R L + +L+ Q++ + Q E+E +LR +QGE ++ LE EL +L
Sbjct: 1684 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1743
Query: 335 R-------ARLQGLEADC--VRGPDGVCL-SGGRGPQGDKAIREQGPREQEPELSFLKQK 384
+ + Q LEA+ VR V L S R + ++ E+ + E E ++
Sbjct: 1744 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1803
Query: 385 EQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASR 421
+ A +AL +E +RQR+L ++D R +A R
Sbjct: 1804 AEEAARLRALAEEAKRQRQL---AEEDAARQRAEAER 1837
Score = 47.4 bits (111), Expect = 5e-05
Identities = 63/274 (22%), Positives = 112/274 (40%), Gaps = 21/274 (7%)
Query: 287 AQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCV 346
++L+ QK ++ + Q + +EEE L+ + ++ A + LE EL ++R+ + D +
Sbjct: 1908 SELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE----DTL 1963
Query: 347 RGPDGVCLSGGRGPQGDKAIREQGPREQEPELS-FLKQKEQLEAEAQALRQELER----- 400
R + L R Q A E+ RE E + L +E+ + +A +E+ER
Sbjct: 1964 RSKEQAELEAARQRQL-AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 2022
Query: 401 --QRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLA--QKLQGLENWGQD-----PG 451
RRL +Q+ R LQ A E H A QK Q L+ Q
Sbjct: 2023 EEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQ 2082
Query: 452 VSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQED- 510
+ A A + +R + +E ++ +AE K EE + R + E
Sbjct: 2083 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2142
Query: 511 REPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRK 544
R+ A + R + E++ +++ E +K
Sbjct: 2143 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2176
Score = 39.7 bits (91), Expect = 0.010
Identities = 88/386 (22%), Positives = 146/386 (37%), Gaps = 44/386 (11%)
Query: 286 QAQLQAQKE--ELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEA 343
QA+ QA++E ELQ M +EE + A + +R+++ ELQQLR +
Sbjct: 1385 QAKAQAEREAKELQQRM------QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1438
Query: 344 DCVRGPDGVCLSGGRGPQGDKAIR---EQGPREQ---EPELSFLKQK-EQLEAEAQALRQ 396
R + S R + + +R E R++ E EL L+ + E+ EA+ + ++
Sbjct: 1439 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1498
Query: 397 ELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDP------ 450
E ER RR + Q ++ + + A A A R Q L+ L ++
Sbjct: 1499 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQ 1558
Query: 451 -------GVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEH--WKHKKEESGRER 501
V A S+ S EK +R + EH +EE+ R
Sbjct: 1559 AEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRA 1618
Query: 502 KKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWR 561
++ + RE A R E R + ++ R +E ++ + EKQK+ R
Sbjct: 1619 QQQAEAERAREEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1675
Query: 562 EGTK--DSHDPLPSWAELLRPKYR---------APQGCSGVDECARQEGLTFFGTELAPV 610
E + + + EL + A Q + E R T G + +
Sbjct: 1676 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL 1735
Query: 611 RQQELASLLRTYLARLPWAGQLTKEL 636
++ELA L R A +L EL
Sbjct: 1736 LEEELARLQREAAAATQKRQELEAEL 1761
Score = 37.4 bits (85), Expect = 0.050
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 39/188 (20%)
Query: 260 DSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQ--SLMHQPKGLEEENAQLRGAL 317
+ V +Q + + + + + +R A+L+ +KE+LQ + + Q K E + Q L
Sbjct: 2430 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2489
Query: 318 QQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPE 377
Q+ +A Q++ SE L R + +E +++ +
Sbjct: 2490 QETQALQQSFLSEKDSLLQRERFIE------------------------------QEKAK 2519
Query: 378 LSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGD-PAHAGLAELGHRL 436
L L Q E A+AQ LR+E +RQ++ + +Q L S+++A R A G+ R
Sbjct: 2520 LEQLFQDEV--AKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGV----RRK 2573
Query: 437 AQKLQGLE 444
++LQ LE
Sbjct: 2574 QEELQQLE 2581
Score = 37.0 bits (84), Expect = 0.065
Identities = 67/306 (21%), Positives = 125/306 (40%), Gaps = 39/306 (12%)
Query: 243 GDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQ 302
G++Q L E+ A + ++ + Q L +LAK ++ +L A +EE +S +
Sbjct: 1729 GEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1788
Query: 303 PKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQG 362
K E A L + A RAL E ++ R Q E D R
Sbjct: 1789 SKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---QLAEEDAARQ-------------- 1831
Query: 363 DKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRG 422
R + R +L+ + + +L+ EA+ +E E + L + +D + Q
Sbjct: 1832 ----RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED--EAFQRRRLE 1885
Query: 423 DPAHAGLAELGHRLAQKLQGLEN-WGQDPGVSANASKAWHQ--------KSHFQNSREWS 473
+ A A++ RLAQ + ++ + G+ + + Q K+ F+ +
Sbjct: 1886 EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGK 1945
Query: 474 GKEKWWDGQRDRKAEHWKHKKEESGRE--RKKNWGGQEDREPAGRWKEGRPRVEES-GSK 530
+ + G+ AE KE++ E R++ +E+R R +E RV++S ++
Sbjct: 1946 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER----RRREAEERVQKSLAAE 2001
Query: 531 KEGKRQ 536
+E RQ
Sbjct: 2002 EEAARQ 2007
Score = 36.6 bits (83), Expect = 0.085
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 3/123 (2%)
Query: 277 KENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRA 336
++ Q ++ QA Q+ E SL+ + + +E+E A+L Q A + L E Q+ +
Sbjct: 2484 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ- 2542
Query: 337 RLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQ 396
Q +E + R + + R + ++ +R + Q+ E +Q+E L E Q LR+
Sbjct: 2543 --QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2600
Query: 397 ELE 399
+L+
Sbjct: 2601 QLQ 2603
Score = 35.0 bits (79), Expect = 0.25
Identities = 67/318 (21%), Positives = 122/318 (38%), Gaps = 17/318 (5%)
Query: 230 RQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQL 289
R+ + + E L+ + Q R Q QA + Q + + A++
Sbjct: 2112 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2171
Query: 290 QAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGP 349
+ K+ + + Q +E+E LR L++ + + L+ ELQ+L+A + EA R
Sbjct: 2172 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQ 2229
Query: 350 DGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQ----LEAEAQALRQELERQRRLL 405
L R Q ++ + + E E L+ K+ L+ EA+ ++Q E R L
Sbjct: 2230 VEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-L 2287
Query: 406 GSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSH 465
Q+ R Q A LAE L +K+Q ++ + + A A QK
Sbjct: 2288 SVAAQEAARLRQLAEEDLAQQRALAE--KMLKEKMQAVQ---EATRLKAEAELLQQQKEL 2342
Query: 466 FQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREP--AGRWKEGRPR 523
Q ++K Q+ + + E+ R+R+ + +R + R
Sbjct: 2343 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2402
Query: 524 VEESGS--KKEGKRQGPK 539
EE +K+ + G K
Sbjct: 2403 AEEDAQRFRKQAEEIGEK 2420
Score = 30.4 bits (67), Expect = 6.1
Identities = 47/183 (25%), Positives = 77/183 (42%), Gaps = 21/183 (11%)
Query: 283 RLLQAQLQAQKEELQSLMHQ-PKGLEEEN---AQLRG-----ALQQGEAFQRALESELQQ 333
R +A+LQ+++ Q + L+EE+ AQLR A QQ EA + E+E +
Sbjct: 1576 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1635
Query: 334 LRARLQGLEADCVR-----GPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLE 388
R +L+ EA +R L+ + + + R + E ++Q+E E
Sbjct: 1636 ERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAE 1695
Query: 389 AEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRL-------AQKLQ 441
E + RQ E + + +Q+L R + +G+ L E RL QK Q
Sbjct: 1696 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1755
Query: 442 GLE 444
LE
Sbjct: 1756 ELE 1758
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 52.8 bits (125), Expect = 1e-06
Identities = 71/320 (22%), Positives = 133/320 (41%), Gaps = 42/320 (13%)
Query: 286 QAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADC 345
+A++QA+ + ++ +EEE +R L+ E + E ELQ LRAR + EA
Sbjct: 1430 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1489
Query: 346 VRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEA-----------QAL 394
+ + + + ++++ R+++ E+ L + + EAEA + L
Sbjct: 1490 RQAQE-------EAERLRRQVQDESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEEL 1541
Query: 395 RQELERQRRLLGSVQQDLERSLQDA--SRGDPAHAGLAELGHRLAQKLQGLENWGQDPGV 452
R + E R L + + R +Q A + A A L A+K LE Q+ V
Sbjct: 1542 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1601
Query: 453 SA-----NASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGG 507
+ A + Q++ + +RE + +R+ E W+ K E+ R R +
Sbjct: 1602 AVAQLREEAERRAQQQAEAERARE----------EAERELERWQLKANEALRLRLQ---- 1647
Query: 508 QEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDS 567
E+ + ++ +++E +R+G E + E +KQ + EGT +
Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT--A 1705
Query: 568 HDPLPSWAELLRPKYRAPQG 587
L + EL+R + QG
Sbjct: 1706 QQRLAAEQELIRLRAETEQG 1725
Score = 48.9 bits (115), Expect = 2e-05
Identities = 44/157 (28%), Positives = 75/157 (47%), Gaps = 16/157 (10%)
Query: 278 ENQDIR---LLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQL 334
E Q +R L + +L+ Q++ + Q E+E +LR +QGE ++ LE EL +L
Sbjct: 1680 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1739
Query: 335 R-------ARLQGLEADC--VRGPDGVCL-SGGRGPQGDKAIREQGPREQEPELSFLKQK 384
+ + Q LEA+ VR V L S R + ++ E+ + E E ++
Sbjct: 1740 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1799
Query: 385 EQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASR 421
+ A +AL +E +RQR+L ++D R +A R
Sbjct: 1800 AEEAARLRALAEEAKRQRQL---AEEDAARQRAEAER 1833
Score = 47.4 bits (111), Expect = 5e-05
Identities = 63/274 (22%), Positives = 112/274 (40%), Gaps = 21/274 (7%)
Query: 287 AQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCV 346
++L+ QK ++ + Q + +EEE L+ + ++ A + LE EL ++R+ + D +
Sbjct: 1904 SELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE----DTL 1959
Query: 347 RGPDGVCLSGGRGPQGDKAIREQGPREQEPELS-FLKQKEQLEAEAQALRQELER----- 400
R + L R Q A E+ RE E + L +E+ + +A +E+ER
Sbjct: 1960 RSKEQAELEAARQRQL-AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 2018
Query: 401 --QRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLA--QKLQGLENWGQD-----PG 451
RRL +Q+ R LQ A E H A QK Q L+ Q
Sbjct: 2019 EEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQ 2078
Query: 452 VSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQED- 510
+ A A + +R + +E ++ +AE K EE + R + E
Sbjct: 2079 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2138
Query: 511 REPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRK 544
R+ A + R + E++ +++ E +K
Sbjct: 2139 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2172
Score = 39.7 bits (91), Expect = 0.010
Identities = 88/386 (22%), Positives = 146/386 (37%), Gaps = 44/386 (11%)
Query: 286 QAQLQAQKE--ELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEA 343
QA+ QA++E ELQ M +EE + A + +R+++ ELQQLR +
Sbjct: 1381 QAKAQAEREAKELQQRM------QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1434
Query: 344 DCVRGPDGVCLSGGRGPQGDKAIR---EQGPREQ---EPELSFLKQK-EQLEAEAQALRQ 396
R + S R + + +R E R++ E EL L+ + E+ EA+ + ++
Sbjct: 1435 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1494
Query: 397 ELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDP------ 450
E ER RR + Q ++ + + A A A R Q L+ L ++
Sbjct: 1495 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQ 1554
Query: 451 -------GVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEH--WKHKKEESGRER 501
V A S+ S EK +R + EH +EE+ R
Sbjct: 1555 AEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRA 1614
Query: 502 KKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWR 561
++ + RE A R E R + ++ R +E ++ + EKQK+ R
Sbjct: 1615 QQQAEAERAREEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1671
Query: 562 EGTK--DSHDPLPSWAELLRPKYR---------APQGCSGVDECARQEGLTFFGTELAPV 610
E + + + EL + A Q + E R T G + +
Sbjct: 1672 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL 1731
Query: 611 RQQELASLLRTYLARLPWAGQLTKEL 636
++ELA L R A +L EL
Sbjct: 1732 LEEELARLQREAAAATQKRQELEAEL 1757
Score = 37.4 bits (85), Expect = 0.050
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 39/188 (20%)
Query: 260 DSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQ--SLMHQPKGLEEENAQLRGAL 317
+ V +Q + + + + + +R A+L+ +KE+LQ + + Q K E + Q L
Sbjct: 2426 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2485
Query: 318 QQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPE 377
Q+ +A Q++ SE L R + +E +++ +
Sbjct: 2486 QETQALQQSFLSEKDSLLQRERFIE------------------------------QEKAK 2515
Query: 378 LSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGD-PAHAGLAELGHRL 436
L L Q E A+AQ LR+E +RQ++ + +Q L S+++A R A G+ R
Sbjct: 2516 LEQLFQDEV--AKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGV----RRK 2569
Query: 437 AQKLQGLE 444
++LQ LE
Sbjct: 2570 QEELQQLE 2577
Score = 37.0 bits (84), Expect = 0.065
Identities = 67/306 (21%), Positives = 125/306 (40%), Gaps = 39/306 (12%)
Query: 243 GDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQ 302
G++Q L E+ A + ++ + Q L +LAK ++ +L A +EE +S +
Sbjct: 1725 GEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1784
Query: 303 PKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQG 362
K E A L + A RAL E ++ R Q E D R
Sbjct: 1785 SKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---QLAEEDAARQ-------------- 1827
Query: 363 DKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRG 422
R + R +L+ + + +L+ EA+ +E E + L + +D + Q
Sbjct: 1828 ----RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED--EAFQRRRLE 1881
Query: 423 DPAHAGLAELGHRLAQKLQGLEN-WGQDPGVSANASKAWHQ--------KSHFQNSREWS 473
+ A A++ RLAQ + ++ + G+ + + Q K+ F+ +
Sbjct: 1882 EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGK 1941
Query: 474 GKEKWWDGQRDRKAEHWKHKKEESGRE--RKKNWGGQEDREPAGRWKEGRPRVEES-GSK 530
+ + G+ AE KE++ E R++ +E+R R +E RV++S ++
Sbjct: 1942 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER----RRREAEERVQKSLAAE 1997
Query: 531 KEGKRQ 536
+E RQ
Sbjct: 1998 EEAARQ 2003
Score = 36.6 bits (83), Expect = 0.085
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 3/123 (2%)
Query: 277 KENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRA 336
++ Q ++ QA Q+ E SL+ + + +E+E A+L Q A + L E Q+ +
Sbjct: 2480 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ- 2538
Query: 337 RLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQ 396
Q +E + R + + R + ++ +R + Q+ E +Q+E L E Q LR+
Sbjct: 2539 --QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2596
Query: 397 ELE 399
+L+
Sbjct: 2597 QLQ 2599
Score = 35.0 bits (79), Expect = 0.25
Identities = 67/318 (21%), Positives = 122/318 (38%), Gaps = 17/318 (5%)
Query: 230 RQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQL 289
R+ + + E L+ + Q R Q QA + Q + + A++
Sbjct: 2108 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2167
Query: 290 QAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGP 349
+ K+ + + Q +E+E LR L++ + + L+ ELQ+L+A + EA R
Sbjct: 2168 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQ 2225
Query: 350 DGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQ----LEAEAQALRQELERQRRLL 405
L R Q ++ + + E E L+ K+ L+ EA+ ++Q E R L
Sbjct: 2226 VEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-L 2283
Query: 406 GSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSH 465
Q+ R Q A LAE L +K+Q ++ + + A A QK
Sbjct: 2284 SVAAQEAARLRQLAEEDLAQQRALAE--KMLKEKMQAVQ---EATRLKAEAELLQQQKEL 2338
Query: 466 FQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREP--AGRWKEGRPR 523
Q ++K Q+ + + E+ R+R+ + +R + R
Sbjct: 2339 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2398
Query: 524 VEESGS--KKEGKRQGPK 539
EE +K+ + G K
Sbjct: 2399 AEEDAQRFRKQAEEIGEK 2416
Score = 30.4 bits (67), Expect = 6.1
Identities = 47/183 (25%), Positives = 77/183 (42%), Gaps = 21/183 (11%)
Query: 283 RLLQAQLQAQKEELQSLMHQ-PKGLEEEN---AQLRG-----ALQQGEAFQRALESELQQ 333
R +A+LQ+++ Q + L+EE+ AQLR A QQ EA + E+E +
Sbjct: 1572 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1631
Query: 334 LRARLQGLEADCVR-----GPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLE 388
R +L+ EA +R L+ + + + R + E ++Q+E E
Sbjct: 1632 ERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAE 1691
Query: 389 AEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRL-------AQKLQ 441
E + RQ E + + +Q+L R + +G+ L E RL QK Q
Sbjct: 1692 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1751
Query: 442 GLE 444
LE
Sbjct: 1752 ELE 1754
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 52.8 bits (125), Expect = 1e-06
Identities = 71/320 (22%), Positives = 133/320 (41%), Gaps = 42/320 (13%)
Query: 286 QAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADC 345
+A++QA+ + ++ +EEE +R L+ E + E ELQ LRAR + EA
Sbjct: 1398 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1457
Query: 346 VRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEA-----------QAL 394
+ + + + ++++ R+++ E+ L + + EAEA + L
Sbjct: 1458 RQAQE-------EAERLRRQVQDESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEEL 1509
Query: 395 RQELERQRRLLGSVQQDLERSLQDA--SRGDPAHAGLAELGHRLAQKLQGLENWGQDPGV 452
R + E R L + + R +Q A + A A L A+K LE Q+ V
Sbjct: 1510 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1569
Query: 453 SA-----NASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGG 507
+ A + Q++ + +RE + +R+ E W+ K E+ R R +
Sbjct: 1570 AVAQLREEAERRAQQQAEAERARE----------EAERELERWQLKANEALRLRLQ---- 1615
Query: 508 QEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDS 567
E+ + ++ +++E +R+G E + E +KQ + EGT +
Sbjct: 1616 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT--A 1673
Query: 568 HDPLPSWAELLRPKYRAPQG 587
L + EL+R + QG
Sbjct: 1674 QQRLAAEQELIRLRAETEQG 1693
Score = 48.9 bits (115), Expect = 2e-05
Identities = 44/157 (28%), Positives = 75/157 (47%), Gaps = 16/157 (10%)
Query: 278 ENQDIR---LLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQL 334
E Q +R L + +L+ Q++ + Q E+E +LR +QGE ++ LE EL +L
Sbjct: 1648 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1707
Query: 335 R-------ARLQGLEADC--VRGPDGVCL-SGGRGPQGDKAIREQGPREQEPELSFLKQK 384
+ + Q LEA+ VR V L S R + ++ E+ + E E ++
Sbjct: 1708 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1767
Query: 385 EQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASR 421
+ A +AL +E +RQR+L ++D R +A R
Sbjct: 1768 AEEAARLRALAEEAKRQRQL---AEEDAARQRAEAER 1801
Score = 47.4 bits (111), Expect = 5e-05
Identities = 63/274 (22%), Positives = 112/274 (40%), Gaps = 21/274 (7%)
Query: 287 AQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCV 346
++L+ QK ++ + Q + +EEE L+ + ++ A + LE EL ++R+ + D +
Sbjct: 1872 SELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE----DTL 1927
Query: 347 RGPDGVCLSGGRGPQGDKAIREQGPREQEPELS-FLKQKEQLEAEAQALRQELER----- 400
R + L R Q A E+ RE E + L +E+ + +A +E+ER
Sbjct: 1928 RSKEQAELEAARQRQL-AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 1986
Query: 401 --QRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLA--QKLQGLENWGQD-----PG 451
RRL +Q+ R LQ A E H A QK Q L+ Q
Sbjct: 1987 EEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQ 2046
Query: 452 VSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQED- 510
+ A A + +R + +E ++ +AE K EE + R + E
Sbjct: 2047 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2106
Query: 511 REPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRK 544
R+ A + R + E++ +++ E +K
Sbjct: 2107 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2140
Score = 39.7 bits (91), Expect = 0.010
Identities = 88/386 (22%), Positives = 146/386 (37%), Gaps = 44/386 (11%)
Query: 286 QAQLQAQKE--ELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEA 343
QA+ QA++E ELQ M +EE + A + +R+++ ELQQLR +
Sbjct: 1349 QAKAQAEREAKELQQRM------QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1402
Query: 344 DCVRGPDGVCLSGGRGPQGDKAIR---EQGPREQ---EPELSFLKQK-EQLEAEAQALRQ 396
R + S R + + +R E R++ E EL L+ + E+ EA+ + ++
Sbjct: 1403 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1462
Query: 397 ELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDP------ 450
E ER RR + Q ++ + + A A A R Q L+ L ++
Sbjct: 1463 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQ 1522
Query: 451 -------GVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEH--WKHKKEESGRER 501
V A S+ S EK +R + EH +EE+ R
Sbjct: 1523 AEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRA 1582
Query: 502 KKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWR 561
++ + RE A R E R + ++ R +E ++ + EKQK+ R
Sbjct: 1583 QQQAEAERAREEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1639
Query: 562 EGTK--DSHDPLPSWAELLRPKYR---------APQGCSGVDECARQEGLTFFGTELAPV 610
E + + + EL + A Q + E R T G + +
Sbjct: 1640 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL 1699
Query: 611 RQQELASLLRTYLARLPWAGQLTKEL 636
++ELA L R A +L EL
Sbjct: 1700 LEEELARLQREAAAATQKRQELEAEL 1725
Score = 37.4 bits (85), Expect = 0.050
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 39/188 (20%)
Query: 260 DSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQ--SLMHQPKGLEEENAQLRGAL 317
+ V +Q + + + + + +R A+L+ +KE+LQ + + Q K E + Q L
Sbjct: 2394 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2453
Query: 318 QQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPE 377
Q+ +A Q++ SE L R + +E +++ +
Sbjct: 2454 QETQALQQSFLSEKDSLLQRERFIE------------------------------QEKAK 2483
Query: 378 LSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGD-PAHAGLAELGHRL 436
L L Q E A+AQ LR+E +RQ++ + +Q L S+++A R A G+ R
Sbjct: 2484 LEQLFQDEV--AKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGV----RRK 2537
Query: 437 AQKLQGLE 444
++LQ LE
Sbjct: 2538 QEELQQLE 2545
Score = 37.0 bits (84), Expect = 0.065
Identities = 67/306 (21%), Positives = 125/306 (40%), Gaps = 39/306 (12%)
Query: 243 GDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQ 302
G++Q L E+ A + ++ + Q L +LAK ++ +L A +EE +S +
Sbjct: 1693 GEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1752
Query: 303 PKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQG 362
K E A L + A RAL E ++ R Q E D R
Sbjct: 1753 SKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---QLAEEDAARQ-------------- 1795
Query: 363 DKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRG 422
R + R +L+ + + +L+ EA+ +E E + L + +D + Q
Sbjct: 1796 ----RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED--EAFQRRRLE 1849
Query: 423 DPAHAGLAELGHRLAQKLQGLEN-WGQDPGVSANASKAWHQ--------KSHFQNSREWS 473
+ A A++ RLAQ + ++ + G+ + + Q K+ F+ +
Sbjct: 1850 EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGK 1909
Query: 474 GKEKWWDGQRDRKAEHWKHKKEESGRE--RKKNWGGQEDREPAGRWKEGRPRVEES-GSK 530
+ + G+ AE KE++ E R++ +E+R R +E RV++S ++
Sbjct: 1910 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER----RRREAEERVQKSLAAE 1965
Query: 531 KEGKRQ 536
+E RQ
Sbjct: 1966 EEAARQ 1971
Score = 36.6 bits (83), Expect = 0.085
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 3/123 (2%)
Query: 277 KENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRA 336
++ Q ++ QA Q+ E SL+ + + +E+E A+L Q A + L E Q+ +
Sbjct: 2448 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ- 2506
Query: 337 RLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQ 396
Q +E + R + + R + ++ +R + Q+ E +Q+E L E Q LR+
Sbjct: 2507 --QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2564
Query: 397 ELE 399
+L+
Sbjct: 2565 QLQ 2567
Score = 35.0 bits (79), Expect = 0.25
Identities = 67/318 (21%), Positives = 122/318 (38%), Gaps = 17/318 (5%)
Query: 230 RQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQL 289
R+ + + E L+ + Q R Q QA + Q + + A++
Sbjct: 2076 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2135
Query: 290 QAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGP 349
+ K+ + + Q +E+E LR L++ + + L+ ELQ+L+A + EA R
Sbjct: 2136 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQ 2193
Query: 350 DGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQ----LEAEAQALRQELERQRRLL 405
L R Q ++ + + E E L+ K+ L+ EA+ ++Q E R L
Sbjct: 2194 VEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-L 2251
Query: 406 GSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSH 465
Q+ R Q A LAE L +K+Q ++ + + A A QK
Sbjct: 2252 SVAAQEAARLRQLAEEDLAQQRALAE--KMLKEKMQAVQ---EATRLKAEAELLQQQKEL 2306
Query: 466 FQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREP--AGRWKEGRPR 523
Q ++K Q+ + + E+ R+R+ + +R + R
Sbjct: 2307 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2366
Query: 524 VEESGS--KKEGKRQGPK 539
EE +K+ + G K
Sbjct: 2367 AEEDAQRFRKQAEEIGEK 2384
Score = 30.4 bits (67), Expect = 6.1
Identities = 47/183 (25%), Positives = 77/183 (42%), Gaps = 21/183 (11%)
Query: 283 RLLQAQLQAQKEELQSLMHQ-PKGLEEEN---AQLRG-----ALQQGEAFQRALESELQQ 333
R +A+LQ+++ Q + L+EE+ AQLR A QQ EA + E+E +
Sbjct: 1540 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1599
Query: 334 LRARLQGLEADCVR-----GPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLE 388
R +L+ EA +R L+ + + + R + E ++Q+E E
Sbjct: 1600 ERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAE 1659
Query: 389 AEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRL-------AQKLQ 441
E + RQ E + + +Q+L R + +G+ L E RL QK Q
Sbjct: 1660 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1719
Query: 442 GLE 444
LE
Sbjct: 1720 ELE 1722
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 52.8 bits (125), Expect = 1e-06
Identities = 71/320 (22%), Positives = 133/320 (41%), Gaps = 42/320 (13%)
Query: 286 QAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADC 345
+A++QA+ + ++ +EEE +R L+ E + E ELQ LRAR + EA
Sbjct: 1567 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1626
Query: 346 VRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEA-----------QAL 394
+ + + + ++++ R+++ E+ L + + EAEA + L
Sbjct: 1627 RQAQE-------EAERLRRQVQDESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEEL 1678
Query: 395 RQELERQRRLLGSVQQDLERSLQDA--SRGDPAHAGLAELGHRLAQKLQGLENWGQDPGV 452
R + E R L + + R +Q A + A A L A+K LE Q+ V
Sbjct: 1679 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1738
Query: 453 SA-----NASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGG 507
+ A + Q++ + +RE + +R+ E W+ K E+ R R +
Sbjct: 1739 AVAQLREEAERRAQQQAEAERARE----------EAERELERWQLKANEALRLRLQ---- 1784
Query: 508 QEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDS 567
E+ + ++ +++E +R+G E + E +KQ + EGT +
Sbjct: 1785 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT--A 1842
Query: 568 HDPLPSWAELLRPKYRAPQG 587
L + EL+R + QG
Sbjct: 1843 QQRLAAEQELIRLRAETEQG 1862
Score = 48.9 bits (115), Expect = 2e-05
Identities = 44/157 (28%), Positives = 75/157 (47%), Gaps = 16/157 (10%)
Query: 278 ENQDIR---LLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQL 334
E Q +R L + +L+ Q++ + Q E+E +LR +QGE ++ LE EL +L
Sbjct: 1817 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1876
Query: 335 R-------ARLQGLEADC--VRGPDGVCL-SGGRGPQGDKAIREQGPREQEPELSFLKQK 384
+ + Q LEA+ VR V L S R + ++ E+ + E E ++
Sbjct: 1877 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1936
Query: 385 EQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASR 421
+ A +AL +E +RQR+L ++D R +A R
Sbjct: 1937 AEEAARLRALAEEAKRQRQL---AEEDAARQRAEAER 1970
Score = 47.4 bits (111), Expect = 5e-05
Identities = 63/274 (22%), Positives = 112/274 (40%), Gaps = 21/274 (7%)
Query: 287 AQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCV 346
++L+ QK ++ + Q + +EEE L+ + ++ A + LE EL ++R+ + D +
Sbjct: 2041 SELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE----DTL 2096
Query: 347 RGPDGVCLSGGRGPQGDKAIREQGPREQEPELS-FLKQKEQLEAEAQALRQELER----- 400
R + L R Q A E+ RE E + L +E+ + +A +E+ER
Sbjct: 2097 RSKEQAELEAARQRQL-AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 2155
Query: 401 --QRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLA--QKLQGLENWGQD-----PG 451
RRL +Q+ R LQ A E H A QK Q L+ Q
Sbjct: 2156 EEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQ 2215
Query: 452 VSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQED- 510
+ A A + +R + +E ++ +AE K EE + R + E
Sbjct: 2216 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2275
Query: 511 REPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRK 544
R+ A + R + E++ +++ E +K
Sbjct: 2276 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2309
Score = 39.7 bits (91), Expect = 0.010
Identities = 88/386 (22%), Positives = 146/386 (37%), Gaps = 44/386 (11%)
Query: 286 QAQLQAQKE--ELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEA 343
QA+ QA++E ELQ M +EE + A + +R+++ ELQQLR +
Sbjct: 1518 QAKAQAEREAKELQQRM------QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1571
Query: 344 DCVRGPDGVCLSGGRGPQGDKAIR---EQGPREQ---EPELSFLKQK-EQLEAEAQALRQ 396
R + S R + + +R E R++ E EL L+ + E+ EA+ + ++
Sbjct: 1572 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1631
Query: 397 ELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDP------ 450
E ER RR + Q ++ + + A A A R Q L+ L ++
Sbjct: 1632 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQ 1691
Query: 451 -------GVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEH--WKHKKEESGRER 501
V A S+ S EK +R + EH +EE+ R
Sbjct: 1692 AEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRA 1751
Query: 502 KKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWR 561
++ + RE A R E R + ++ R +E ++ + EKQK+ R
Sbjct: 1752 QQQAEAERAREEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1808
Query: 562 EGTK--DSHDPLPSWAELLRPKYR---------APQGCSGVDECARQEGLTFFGTELAPV 610
E + + + EL + A Q + E R T G + +
Sbjct: 1809 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL 1868
Query: 611 RQQELASLLRTYLARLPWAGQLTKEL 636
++ELA L R A +L EL
Sbjct: 1869 LEEELARLQREAAAATQKRQELEAEL 1894
Score = 37.4 bits (85), Expect = 0.050
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 39/188 (20%)
Query: 260 DSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQ--SLMHQPKGLEEENAQLRGAL 317
+ V +Q + + + + + +R A+L+ +KE+LQ + + Q K E + Q L
Sbjct: 2563 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2622
Query: 318 QQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPE 377
Q+ +A Q++ SE L R + +E +++ +
Sbjct: 2623 QETQALQQSFLSEKDSLLQRERFIE------------------------------QEKAK 2652
Query: 378 LSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGD-PAHAGLAELGHRL 436
L L Q E A+AQ LR+E +RQ++ + +Q L S+++A R A G+ R
Sbjct: 2653 LEQLFQDEV--AKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGV----RRK 2706
Query: 437 AQKLQGLE 444
++LQ LE
Sbjct: 2707 QEELQQLE 2714
Score = 37.0 bits (84), Expect = 0.065
Identities = 67/306 (21%), Positives = 125/306 (40%), Gaps = 39/306 (12%)
Query: 243 GDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQ 302
G++Q L E+ A + ++ + Q L +LAK ++ +L A +EE +S +
Sbjct: 1862 GEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1921
Query: 303 PKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQG 362
K E A L + A RAL E ++ R Q E D R
Sbjct: 1922 SKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---QLAEEDAARQ-------------- 1964
Query: 363 DKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRG 422
R + R +L+ + + +L+ EA+ +E E + L + +D + Q
Sbjct: 1965 ----RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED--EAFQRRRLE 2018
Query: 423 DPAHAGLAELGHRLAQKLQGLEN-WGQDPGVSANASKAWHQ--------KSHFQNSREWS 473
+ A A++ RLAQ + ++ + G+ + + Q K+ F+ +
Sbjct: 2019 EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGK 2078
Query: 474 GKEKWWDGQRDRKAEHWKHKKEESGRE--RKKNWGGQEDREPAGRWKEGRPRVEES-GSK 530
+ + G+ AE KE++ E R++ +E+R R +E RV++S ++
Sbjct: 2079 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER----RRREAEERVQKSLAAE 2134
Query: 531 KEGKRQ 536
+E RQ
Sbjct: 2135 EEAARQ 2140
Score = 36.6 bits (83), Expect = 0.085
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 3/123 (2%)
Query: 277 KENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRA 336
++ Q ++ QA Q+ E SL+ + + +E+E A+L Q A + L E Q+ +
Sbjct: 2617 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ- 2675
Query: 337 RLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQ 396
Q +E + R + + R + ++ +R + Q+ E +Q+E L E Q LR+
Sbjct: 2676 --QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2733
Query: 397 ELE 399
+L+
Sbjct: 2734 QLQ 2736
Score = 35.0 bits (79), Expect = 0.25
Identities = 67/318 (21%), Positives = 122/318 (38%), Gaps = 17/318 (5%)
Query: 230 RQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQL 289
R+ + + E L+ + Q R Q QA + Q + + A++
Sbjct: 2245 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2304
Query: 290 QAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGP 349
+ K+ + + Q +E+E LR L++ + + L+ ELQ+L+A + EA R
Sbjct: 2305 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQ 2362
Query: 350 DGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQ----LEAEAQALRQELERQRRLL 405
L R Q ++ + + E E L+ K+ L+ EA+ ++Q E R L
Sbjct: 2363 VEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-L 2420
Query: 406 GSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSH 465
Q+ R Q A LAE L +K+Q ++ + + A A QK
Sbjct: 2421 SVAAQEAARLRQLAEEDLAQQRALAE--KMLKEKMQAVQ---EATRLKAEAELLQQQKEL 2475
Query: 466 FQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREP--AGRWKEGRPR 523
Q ++K Q+ + + E+ R+R+ + +R + R
Sbjct: 2476 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2535
Query: 524 VEESGS--KKEGKRQGPK 539
EE +K+ + G K
Sbjct: 2536 AEEDAQRFRKQAEEIGEK 2553
Score = 30.4 bits (67), Expect = 6.1
Identities = 47/183 (25%), Positives = 77/183 (42%), Gaps = 21/183 (11%)
Query: 283 RLLQAQLQAQKEELQSLMHQ-PKGLEEEN---AQLRG-----ALQQGEAFQRALESELQQ 333
R +A+LQ+++ Q + L+EE+ AQLR A QQ EA + E+E +
Sbjct: 1709 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1768
Query: 334 LRARLQGLEADCVR-----GPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLE 388
R +L+ EA +R L+ + + + R + E ++Q+E E
Sbjct: 1769 ERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAE 1828
Query: 389 AEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRL-------AQKLQ 441
E + RQ E + + +Q+L R + +G+ L E RL QK Q
Sbjct: 1829 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1888
Query: 442 GLE 444
LE
Sbjct: 1889 ELE 1891
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 52.8 bits (125), Expect = 1e-06
Identities = 71/320 (22%), Positives = 133/320 (41%), Gaps = 42/320 (13%)
Query: 286 QAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADC 345
+A++QA+ + ++ +EEE +R L+ E + E ELQ LRAR + EA
Sbjct: 1408 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1467
Query: 346 VRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEA-----------QAL 394
+ + + + ++++ R+++ E+ L + + EAEA + L
Sbjct: 1468 RQAQE-------EAERLRRQVQDESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEEL 1519
Query: 395 RQELERQRRLLGSVQQDLERSLQDA--SRGDPAHAGLAELGHRLAQKLQGLENWGQDPGV 452
R + E R L + + R +Q A + A A L A+K LE Q+ V
Sbjct: 1520 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1579
Query: 453 SA-----NASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGG 507
+ A + Q++ + +RE + +R+ E W+ K E+ R R +
Sbjct: 1580 AVAQLREEAERRAQQQAEAERARE----------EAERELERWQLKANEALRLRLQ---- 1625
Query: 508 QEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDS 567
E+ + ++ +++E +R+G E + E +KQ + EGT +
Sbjct: 1626 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT--A 1683
Query: 568 HDPLPSWAELLRPKYRAPQG 587
L + EL+R + QG
Sbjct: 1684 QQRLAAEQELIRLRAETEQG 1703
Score = 48.9 bits (115), Expect = 2e-05
Identities = 44/157 (28%), Positives = 75/157 (47%), Gaps = 16/157 (10%)
Query: 278 ENQDIR---LLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQL 334
E Q +R L + +L+ Q++ + Q E+E +LR +QGE ++ LE EL +L
Sbjct: 1658 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1717
Query: 335 R-------ARLQGLEADC--VRGPDGVCL-SGGRGPQGDKAIREQGPREQEPELSFLKQK 384
+ + Q LEA+ VR V L S R + ++ E+ + E E ++
Sbjct: 1718 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1777
Query: 385 EQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASR 421
+ A +AL +E +RQR+L ++D R +A R
Sbjct: 1778 AEEAARLRALAEEAKRQRQL---AEEDAARQRAEAER 1811
Score = 47.4 bits (111), Expect = 5e-05
Identities = 63/274 (22%), Positives = 112/274 (40%), Gaps = 21/274 (7%)
Query: 287 AQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCV 346
++L+ QK ++ + Q + +EEE L+ + ++ A + LE EL ++R+ + D +
Sbjct: 1882 SELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE----DTL 1937
Query: 347 RGPDGVCLSGGRGPQGDKAIREQGPREQEPELS-FLKQKEQLEAEAQALRQELER----- 400
R + L R Q A E+ RE E + L +E+ + +A +E+ER
Sbjct: 1938 RSKEQAELEAARQRQL-AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 1996
Query: 401 --QRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLA--QKLQGLENWGQD-----PG 451
RRL +Q+ R LQ A E H A QK Q L+ Q
Sbjct: 1997 EEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQ 2056
Query: 452 VSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQED- 510
+ A A + +R + +E ++ +AE K EE + R + E
Sbjct: 2057 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2116
Query: 511 REPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRK 544
R+ A + R + E++ +++ E +K
Sbjct: 2117 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2150
Score = 39.7 bits (91), Expect = 0.010
Identities = 88/386 (22%), Positives = 146/386 (37%), Gaps = 44/386 (11%)
Query: 286 QAQLQAQKE--ELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEA 343
QA+ QA++E ELQ M +EE + A + +R+++ ELQQLR +
Sbjct: 1359 QAKAQAEREAKELQQRM------QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1412
Query: 344 DCVRGPDGVCLSGGRGPQGDKAIR---EQGPREQ---EPELSFLKQK-EQLEAEAQALRQ 396
R + S R + + +R E R++ E EL L+ + E+ EA+ + ++
Sbjct: 1413 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1472
Query: 397 ELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDP------ 450
E ER RR + Q ++ + + A A A R Q L+ L ++
Sbjct: 1473 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQ 1532
Query: 451 -------GVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEH--WKHKKEESGRER 501
V A S+ S EK +R + EH +EE+ R
Sbjct: 1533 AEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRA 1592
Query: 502 KKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWR 561
++ + RE A R E R + ++ R +E ++ + EKQK+ R
Sbjct: 1593 QQQAEAERAREEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1649
Query: 562 EGTK--DSHDPLPSWAELLRPKYR---------APQGCSGVDECARQEGLTFFGTELAPV 610
E + + + EL + A Q + E R T G + +
Sbjct: 1650 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL 1709
Query: 611 RQQELASLLRTYLARLPWAGQLTKEL 636
++ELA L R A +L EL
Sbjct: 1710 LEEELARLQREAAAATQKRQELEAEL 1735
Score = 37.4 bits (85), Expect = 0.050
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 39/188 (20%)
Query: 260 DSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQ--SLMHQPKGLEEENAQLRGAL 317
+ V +Q + + + + + +R A+L+ +KE+LQ + + Q K E + Q L
Sbjct: 2404 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2463
Query: 318 QQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPE 377
Q+ +A Q++ SE L R + +E +++ +
Sbjct: 2464 QETQALQQSFLSEKDSLLQRERFIE------------------------------QEKAK 2493
Query: 378 LSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGD-PAHAGLAELGHRL 436
L L Q E A+AQ LR+E +RQ++ + +Q L S+++A R A G+ R
Sbjct: 2494 LEQLFQDEV--AKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGV----RRK 2547
Query: 437 AQKLQGLE 444
++LQ LE
Sbjct: 2548 QEELQQLE 2555
Score = 37.0 bits (84), Expect = 0.065
Identities = 67/306 (21%), Positives = 125/306 (40%), Gaps = 39/306 (12%)
Query: 243 GDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQ 302
G++Q L E+ A + ++ + Q L +LAK ++ +L A +EE +S +
Sbjct: 1703 GEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1762
Query: 303 PKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQG 362
K E A L + A RAL E ++ R Q E D R
Sbjct: 1763 SKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---QLAEEDAARQ-------------- 1805
Query: 363 DKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRG 422
R + R +L+ + + +L+ EA+ +E E + L + +D + Q
Sbjct: 1806 ----RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED--EAFQRRRLE 1859
Query: 423 DPAHAGLAELGHRLAQKLQGLEN-WGQDPGVSANASKAWHQ--------KSHFQNSREWS 473
+ A A++ RLAQ + ++ + G+ + + Q K+ F+ +
Sbjct: 1860 EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGK 1919
Query: 474 GKEKWWDGQRDRKAEHWKHKKEESGRE--RKKNWGGQEDREPAGRWKEGRPRVEES-GSK 530
+ + G+ AE KE++ E R++ +E+R R +E RV++S ++
Sbjct: 1920 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER----RRREAEERVQKSLAAE 1975
Query: 531 KEGKRQ 536
+E RQ
Sbjct: 1976 EEAARQ 1981
Score = 36.6 bits (83), Expect = 0.085
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 3/123 (2%)
Query: 277 KENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRA 336
++ Q ++ QA Q+ E SL+ + + +E+E A+L Q A + L E Q+ +
Sbjct: 2458 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ- 2516
Query: 337 RLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQ 396
Q +E + R + + R + ++ +R + Q+ E +Q+E L E Q LR+
Sbjct: 2517 --QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2574
Query: 397 ELE 399
+L+
Sbjct: 2575 QLQ 2577
Score = 35.0 bits (79), Expect = 0.25
Identities = 67/318 (21%), Positives = 122/318 (38%), Gaps = 17/318 (5%)
Query: 230 RQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQL 289
R+ + + E L+ + Q R Q QA + Q + + A++
Sbjct: 2086 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2145
Query: 290 QAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGP 349
+ K+ + + Q +E+E LR L++ + + L+ ELQ+L+A + EA R
Sbjct: 2146 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQ 2203
Query: 350 DGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQ----LEAEAQALRQELERQRRLL 405
L R Q ++ + + E E L+ K+ L+ EA+ ++Q E R L
Sbjct: 2204 VEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-L 2261
Query: 406 GSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSH 465
Q+ R Q A LAE L +K+Q ++ + + A A QK
Sbjct: 2262 SVAAQEAARLRQLAEEDLAQQRALAE--KMLKEKMQAVQ---EATRLKAEAELLQQQKEL 2316
Query: 466 FQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREP--AGRWKEGRPR 523
Q ++K Q+ + + E+ R+R+ + +R + R
Sbjct: 2317 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2376
Query: 524 VEESGS--KKEGKRQGPK 539
EE +K+ + G K
Sbjct: 2377 AEEDAQRFRKQAEEIGEK 2394
Score = 30.4 bits (67), Expect = 6.1
Identities = 47/183 (25%), Positives = 77/183 (42%), Gaps = 21/183 (11%)
Query: 283 RLLQAQLQAQKEELQSLMHQ-PKGLEEEN---AQLRG-----ALQQGEAFQRALESELQQ 333
R +A+LQ+++ Q + L+EE+ AQLR A QQ EA + E+E +
Sbjct: 1550 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1609
Query: 334 LRARLQGLEADCVR-----GPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLE 388
R +L+ EA +R L+ + + + R + E ++Q+E E
Sbjct: 1610 ERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAE 1669
Query: 389 AEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRL-------AQKLQ 441
E + RQ E + + +Q+L R + +G+ L E RL QK Q
Sbjct: 1670 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1729
Query: 442 GLE 444
LE
Sbjct: 1730 ELE 1732
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 52.8 bits (125), Expect = 1e-06
Identities = 71/320 (22%), Positives = 133/320 (41%), Gaps = 42/320 (13%)
Query: 286 QAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADC 345
+A++QA+ + ++ +EEE +R L+ E + E ELQ LRAR + EA
Sbjct: 1416 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1475
Query: 346 VRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEA-----------QAL 394
+ + + + ++++ R+++ E+ L + + EAEA + L
Sbjct: 1476 RQAQE-------EAERLRRQVQDESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEEL 1527
Query: 395 RQELERQRRLLGSVQQDLERSLQDA--SRGDPAHAGLAELGHRLAQKLQGLENWGQDPGV 452
R + E R L + + R +Q A + A A L A+K LE Q+ V
Sbjct: 1528 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1587
Query: 453 SA-----NASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGG 507
+ A + Q++ + +RE + +R+ E W+ K E+ R R +
Sbjct: 1588 AVAQLREEAERRAQQQAEAERARE----------EAERELERWQLKANEALRLRLQ---- 1633
Query: 508 QEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDS 567
E+ + ++ +++E +R+G E + E +KQ + EGT +
Sbjct: 1634 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT--A 1691
Query: 568 HDPLPSWAELLRPKYRAPQG 587
L + EL+R + QG
Sbjct: 1692 QQRLAAEQELIRLRAETEQG 1711
Score = 48.9 bits (115), Expect = 2e-05
Identities = 44/157 (28%), Positives = 75/157 (47%), Gaps = 16/157 (10%)
Query: 278 ENQDIR---LLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQL 334
E Q +R L + +L+ Q++ + Q E+E +LR +QGE ++ LE EL +L
Sbjct: 1666 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1725
Query: 335 R-------ARLQGLEADC--VRGPDGVCL-SGGRGPQGDKAIREQGPREQEPELSFLKQK 384
+ + Q LEA+ VR V L S R + ++ E+ + E E ++
Sbjct: 1726 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1785
Query: 385 EQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASR 421
+ A +AL +E +RQR+L ++D R +A R
Sbjct: 1786 AEEAARLRALAEEAKRQRQL---AEEDAARQRAEAER 1819
Score = 47.4 bits (111), Expect = 5e-05
Identities = 63/274 (22%), Positives = 112/274 (40%), Gaps = 21/274 (7%)
Query: 287 AQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCV 346
++L+ QK ++ + Q + +EEE L+ + ++ A + LE EL ++R+ + D +
Sbjct: 1890 SELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE----DTL 1945
Query: 347 RGPDGVCLSGGRGPQGDKAIREQGPREQEPELS-FLKQKEQLEAEAQALRQELER----- 400
R + L R Q A E+ RE E + L +E+ + +A +E+ER
Sbjct: 1946 RSKEQAELEAARQRQL-AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 2004
Query: 401 --QRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLA--QKLQGLENWGQD-----PG 451
RRL +Q+ R LQ A E H A QK Q L+ Q
Sbjct: 2005 EEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQ 2064
Query: 452 VSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQED- 510
+ A A + +R + +E ++ +AE K EE + R + E
Sbjct: 2065 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2124
Query: 511 REPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRK 544
R+ A + R + E++ +++ E +K
Sbjct: 2125 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2158
Score = 39.7 bits (91), Expect = 0.010
Identities = 88/386 (22%), Positives = 146/386 (37%), Gaps = 44/386 (11%)
Query: 286 QAQLQAQKE--ELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEA 343
QA+ QA++E ELQ M +EE + A + +R+++ ELQQLR +
Sbjct: 1367 QAKAQAEREAKELQQRM------QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1420
Query: 344 DCVRGPDGVCLSGGRGPQGDKAIR---EQGPREQ---EPELSFLKQK-EQLEAEAQALRQ 396
R + S R + + +R E R++ E EL L+ + E+ EA+ + ++
Sbjct: 1421 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1480
Query: 397 ELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDP------ 450
E ER RR + Q ++ + + A A A R Q L+ L ++
Sbjct: 1481 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQ 1540
Query: 451 -------GVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEH--WKHKKEESGRER 501
V A S+ S EK +R + EH +EE+ R
Sbjct: 1541 AEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRA 1600
Query: 502 KKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWR 561
++ + RE A R E R + ++ R +E ++ + EKQK+ R
Sbjct: 1601 QQQAEAERAREEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1657
Query: 562 EGTK--DSHDPLPSWAELLRPKYR---------APQGCSGVDECARQEGLTFFGTELAPV 610
E + + + EL + A Q + E R T G + +
Sbjct: 1658 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL 1717
Query: 611 RQQELASLLRTYLARLPWAGQLTKEL 636
++ELA L R A +L EL
Sbjct: 1718 LEEELARLQREAAAATQKRQELEAEL 1743
Score = 37.4 bits (85), Expect = 0.050
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 39/188 (20%)
Query: 260 DSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQ--SLMHQPKGLEEENAQLRGAL 317
+ V +Q + + + + + +R A+L+ +KE+LQ + + Q K E + Q L
Sbjct: 2412 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2471
Query: 318 QQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPE 377
Q+ +A Q++ SE L R + +E +++ +
Sbjct: 2472 QETQALQQSFLSEKDSLLQRERFIE------------------------------QEKAK 2501
Query: 378 LSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGD-PAHAGLAELGHRL 436
L L Q E A+AQ LR+E +RQ++ + +Q L S+++A R A G+ R
Sbjct: 2502 LEQLFQDEV--AKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGV----RRK 2555
Query: 437 AQKLQGLE 444
++LQ LE
Sbjct: 2556 QEELQQLE 2563
Score = 37.0 bits (84), Expect = 0.065
Identities = 67/306 (21%), Positives = 125/306 (40%), Gaps = 39/306 (12%)
Query: 243 GDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQ 302
G++Q L E+ A + ++ + Q L +LAK ++ +L A +EE +S +
Sbjct: 1711 GEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1770
Query: 303 PKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQG 362
K E A L + A RAL E ++ R Q E D R
Sbjct: 1771 SKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---QLAEEDAARQ-------------- 1813
Query: 363 DKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRG 422
R + R +L+ + + +L+ EA+ +E E + L + +D + Q
Sbjct: 1814 ----RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED--EAFQRRRLE 1867
Query: 423 DPAHAGLAELGHRLAQKLQGLEN-WGQDPGVSANASKAWHQ--------KSHFQNSREWS 473
+ A A++ RLAQ + ++ + G+ + + Q K+ F+ +
Sbjct: 1868 EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGK 1927
Query: 474 GKEKWWDGQRDRKAEHWKHKKEESGRE--RKKNWGGQEDREPAGRWKEGRPRVEES-GSK 530
+ + G+ AE KE++ E R++ +E+R R +E RV++S ++
Sbjct: 1928 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER----RRREAEERVQKSLAAE 1983
Query: 531 KEGKRQ 536
+E RQ
Sbjct: 1984 EEAARQ 1989
Score = 36.6 bits (83), Expect = 0.085
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 3/123 (2%)
Query: 277 KENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRA 336
++ Q ++ QA Q+ E SL+ + + +E+E A+L Q A + L E Q+ +
Sbjct: 2466 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ- 2524
Query: 337 RLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQ 396
Q +E + R + + R + ++ +R + Q+ E +Q+E L E Q LR+
Sbjct: 2525 --QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2582
Query: 397 ELE 399
+L+
Sbjct: 2583 QLQ 2585
Score = 35.0 bits (79), Expect = 0.25
Identities = 67/318 (21%), Positives = 122/318 (38%), Gaps = 17/318 (5%)
Query: 230 RQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQL 289
R+ + + E L+ + Q R Q QA + Q + + A++
Sbjct: 2094 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2153
Query: 290 QAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGP 349
+ K+ + + Q +E+E LR L++ + + L+ ELQ+L+A + EA R
Sbjct: 2154 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQ 2211
Query: 350 DGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQ----LEAEAQALRQELERQRRLL 405
L R Q ++ + + E E L+ K+ L+ EA+ ++Q E R L
Sbjct: 2212 VEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-L 2269
Query: 406 GSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSH 465
Q+ R Q A LAE L +K+Q ++ + + A A QK
Sbjct: 2270 SVAAQEAARLRQLAEEDLAQQRALAE--KMLKEKMQAVQ---EATRLKAEAELLQQQKEL 2324
Query: 466 FQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREP--AGRWKEGRPR 523
Q ++K Q+ + + E+ R+R+ + +R + R
Sbjct: 2325 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2384
Query: 524 VEESGS--KKEGKRQGPK 539
EE +K+ + G K
Sbjct: 2385 AEEDAQRFRKQAEEIGEK 2402
Score = 30.4 bits (67), Expect = 6.1
Identities = 47/183 (25%), Positives = 77/183 (42%), Gaps = 21/183 (11%)
Query: 283 RLLQAQLQAQKEELQSLMHQ-PKGLEEEN---AQLRG-----ALQQGEAFQRALESELQQ 333
R +A+LQ+++ Q + L+EE+ AQLR A QQ EA + E+E +
Sbjct: 1558 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1617
Query: 334 LRARLQGLEADCVR-----GPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLE 388
R +L+ EA +R L+ + + + R + E ++Q+E E
Sbjct: 1618 ERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAE 1677
Query: 389 AEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRL-------AQKLQ 441
E + RQ E + + +Q+L R + +G+ L E RL QK Q
Sbjct: 1678 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1737
Query: 442 GLE 444
LE
Sbjct: 1738 ELE 1740
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 52.8 bits (125), Expect = 1e-06
Identities = 71/320 (22%), Positives = 133/320 (41%), Gaps = 42/320 (13%)
Query: 286 QAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADC 345
+A++QA+ + ++ +EEE +R L+ E + E ELQ LRAR + EA
Sbjct: 1457 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1516
Query: 346 VRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEA-----------QAL 394
+ + + + ++++ R+++ E+ L + + EAEA + L
Sbjct: 1517 RQAQE-------EAERLRRQVQDESQRKRQAEVE-LASRVKAEAEAAREKQRALQALEEL 1568
Query: 395 RQELERQRRLLGSVQQDLERSLQDA--SRGDPAHAGLAELGHRLAQKLQGLENWGQDPGV 452
R + E R L + + R +Q A + A A L A+K LE Q+ V
Sbjct: 1569 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1628
Query: 453 SA-----NASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGG 507
+ A + Q++ + +RE + +R+ E W+ K E+ R R +
Sbjct: 1629 AVAQLREEAERRAQQQAEAERARE----------EAERELERWQLKANEALRLRLQ---- 1674
Query: 508 QEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDS 567
E+ + ++ +++E +R+G E + E +KQ + EGT +
Sbjct: 1675 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT--A 1732
Query: 568 HDPLPSWAELLRPKYRAPQG 587
L + EL+R + QG
Sbjct: 1733 QQRLAAEQELIRLRAETEQG 1752
Score = 48.9 bits (115), Expect = 2e-05
Identities = 44/157 (28%), Positives = 75/157 (47%), Gaps = 16/157 (10%)
Query: 278 ENQDIR---LLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQL 334
E Q +R L + +L+ Q++ + Q E+E +LR +QGE ++ LE EL +L
Sbjct: 1707 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1766
Query: 335 R-------ARLQGLEADC--VRGPDGVCL-SGGRGPQGDKAIREQGPREQEPELSFLKQK 384
+ + Q LEA+ VR V L S R + ++ E+ + E E ++
Sbjct: 1767 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1826
Query: 385 EQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASR 421
+ A +AL +E +RQR+L ++D R +A R
Sbjct: 1827 AEEAARLRALAEEAKRQRQL---AEEDAARQRAEAER 1860
Score = 47.4 bits (111), Expect = 5e-05
Identities = 63/274 (22%), Positives = 112/274 (40%), Gaps = 21/274 (7%)
Query: 287 AQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCV 346
++L+ QK ++ + Q + +EEE L+ + ++ A + LE EL ++R+ + D +
Sbjct: 1931 SELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE----DTL 1986
Query: 347 RGPDGVCLSGGRGPQGDKAIREQGPREQEPELS-FLKQKEQLEAEAQALRQELER----- 400
R + L R Q A E+ RE E + L +E+ + +A +E+ER
Sbjct: 1987 RSKEQAELEAARQRQL-AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 2045
Query: 401 --QRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLA--QKLQGLENWGQD-----PG 451
RRL +Q+ R LQ A E H A QK Q L+ Q
Sbjct: 2046 EEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQ 2105
Query: 452 VSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQED- 510
+ A A + +R + +E ++ +AE K EE + R + E
Sbjct: 2106 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2165
Query: 511 REPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRK 544
R+ A + R + E++ +++ E +K
Sbjct: 2166 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2199
Score = 39.7 bits (91), Expect = 0.010
Identities = 88/386 (22%), Positives = 146/386 (37%), Gaps = 44/386 (11%)
Query: 286 QAQLQAQKE--ELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEA 343
QA+ QA++E ELQ M +EE + A + +R+++ ELQQLR +
Sbjct: 1408 QAKAQAEREAKELQQRM------QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1461
Query: 344 DCVRGPDGVCLSGGRGPQGDKAIR---EQGPREQ---EPELSFLKQK-EQLEAEAQALRQ 396
R + S R + + +R E R++ E EL L+ + E+ EA+ + ++
Sbjct: 1462 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1521
Query: 397 ELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDP------ 450
E ER RR + Q ++ + + A A A R Q L+ L ++
Sbjct: 1522 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQ 1581
Query: 451 -------GVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEH--WKHKKEESGRER 501
V A S+ S EK +R + EH +EE+ R
Sbjct: 1582 AEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRA 1641
Query: 502 KKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWR 561
++ + RE A R E R + ++ R +E ++ + EKQK+ R
Sbjct: 1642 QQQAEAERAREEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER 1698
Query: 562 EGTK--DSHDPLPSWAELLRPKYR---------APQGCSGVDECARQEGLTFFGTELAPV 610
E + + + EL + A Q + E R T G + +
Sbjct: 1699 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQL 1758
Query: 611 RQQELASLLRTYLARLPWAGQLTKEL 636
++ELA L R A +L EL
Sbjct: 1759 LEEELARLQREAAAATQKRQELEAEL 1784
Score = 37.4 bits (85), Expect = 0.050
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 39/188 (20%)
Query: 260 DSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQ--SLMHQPKGLEEENAQLRGAL 317
+ V +Q + + + + + +R A+L+ +KE+LQ + + Q K E + Q L
Sbjct: 2453 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLL 2512
Query: 318 QQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPE 377
Q+ +A Q++ SE L R + +E +++ +
Sbjct: 2513 QETQALQQSFLSEKDSLLQRERFIE------------------------------QEKAK 2542
Query: 378 LSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGD-PAHAGLAELGHRL 436
L L Q E A+AQ LR+E +RQ++ + +Q L S+++A R A G+ R
Sbjct: 2543 LEQLFQDEV--AKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGV----RRK 2596
Query: 437 AQKLQGLE 444
++LQ LE
Sbjct: 2597 QEELQQLE 2604
Score = 37.0 bits (84), Expect = 0.065
Identities = 67/306 (21%), Positives = 125/306 (40%), Gaps = 39/306 (12%)
Query: 243 GDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQ 302
G++Q L E+ A + ++ + Q L +LAK ++ +L A +EE +S +
Sbjct: 1752 GEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1811
Query: 303 PKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQG 362
K E A L + A RAL E ++ R Q E D R
Sbjct: 1812 SKQRLEAEAGRFRELAEEAARLRALAEEAKRQR---QLAEEDAARQ-------------- 1854
Query: 363 DKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRG 422
R + R +L+ + + +L+ EA+ +E E + L + +D + Q
Sbjct: 1855 ----RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED--EAFQRRRLE 1908
Query: 423 DPAHAGLAELGHRLAQKLQGLEN-WGQDPGVSANASKAWHQ--------KSHFQNSREWS 473
+ A A++ RLAQ + ++ + G+ + + Q K+ F+ +
Sbjct: 1909 EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGK 1968
Query: 474 GKEKWWDGQRDRKAEHWKHKKEESGRE--RKKNWGGQEDREPAGRWKEGRPRVEES-GSK 530
+ + G+ AE KE++ E R++ +E+R R +E RV++S ++
Sbjct: 1969 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER----RRREAEERVQKSLAAE 2024
Query: 531 KEGKRQ 536
+E RQ
Sbjct: 2025 EEAARQ 2030
Score = 36.6 bits (83), Expect = 0.085
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 3/123 (2%)
Query: 277 KENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRA 336
++ Q ++ QA Q+ E SL+ + + +E+E A+L Q A + L E Q+ +
Sbjct: 2507 QQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ- 2565
Query: 337 RLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQ 396
Q +E + R + + R + ++ +R + Q+ E +Q+E L E Q LR+
Sbjct: 2566 --QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2623
Query: 397 ELE 399
+L+
Sbjct: 2624 QLQ 2626
Score = 35.0 bits (79), Expect = 0.25
Identities = 67/318 (21%), Positives = 122/318 (38%), Gaps = 17/318 (5%)
Query: 230 RQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQL 289
R+ + + E L+ + Q R Q QA + Q + + A++
Sbjct: 2135 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2194
Query: 290 QAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGP 349
+ K+ + + Q +E+E LR L++ + + L+ ELQ+L+A + EA R
Sbjct: 2195 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQ 2252
Query: 350 DGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQ----LEAEAQALRQELERQRRLL 405
L R Q ++ + + E E L+ K+ L+ EA+ ++Q E R L
Sbjct: 2253 VEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-L 2310
Query: 406 GSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSH 465
Q+ R Q A LAE L +K+Q ++ + + A A QK
Sbjct: 2311 SVAAQEAARLRQLAEEDLAQQRALAE--KMLKEKMQAVQ---EATRLKAEAELLQQQKEL 2365
Query: 466 FQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREP--AGRWKEGRPR 523
Q ++K Q+ + + E+ R+R+ + +R + R
Sbjct: 2366 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2425
Query: 524 VEESGS--KKEGKRQGPK 539
EE +K+ + G K
Sbjct: 2426 AEEDAQRFRKQAEEIGEK 2443
Score = 30.4 bits (67), Expect = 6.1
Identities = 47/183 (25%), Positives = 77/183 (42%), Gaps = 21/183 (11%)
Query: 283 RLLQAQLQAQKEELQSLMHQ-PKGLEEEN---AQLRG-----ALQQGEAFQRALESELQQ 333
R +A+LQ+++ Q + L+EE+ AQLR A QQ EA + E+E +
Sbjct: 1599 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1658
Query: 334 LRARLQGLEADCVR-----GPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLE 388
R +L+ EA +R L+ + + + R + E ++Q+E E
Sbjct: 1659 ERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAE 1718
Query: 389 AEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRL-------AQKLQ 441
E + RQ E + + +Q+L R + +G+ L E RL QK Q
Sbjct: 1719 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1778
Query: 442 GLE 444
LE
Sbjct: 1779 ELE 1781
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 52.0 bits (123), Expect = 2e-06
Identities = 58/201 (28%), Positives = 97/201 (48%), Gaps = 34/201 (16%)
Query: 272 LDKLAKENQDIRLLQAQLQAQKEELQSLMHQPK-GLEEENAQLRGALQQGEAFQRALESE 330
L K+ + R+ KE+ +L+ + + + +E +LR LQ+ E + E
Sbjct: 1222 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRE 1281
Query: 331 LQQLRARLQGLEADCVR-GPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQK-EQLE 388
LQ+LR +++ L+++ R G + L QG A+ E+ +E E L+Q+ + E
Sbjct: 1282 LQELRRQMKMLDSENTRLGRELAEL------QGRLALGERAEKESRRETLGLRQRLLKGE 1335
Query: 389 AEAQALRQELE---------------RQRRLLGSVQQ--DLERSLQDASRG-----DPAH 426
A + +RQEL+ R+RRLLGS+++ E+ D +RG + A
Sbjct: 1336 ASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAAR 1395
Query: 427 AGLAELGHRLAQ---KLQGLE 444
A AELG RL+ + QGLE
Sbjct: 1396 AEAAELGLRLSAAEGRAQGLE 1416
Score = 49.7 bits (117), Expect = 1e-05
Identities = 50/167 (29%), Positives = 71/167 (42%), Gaps = 21/167 (12%)
Query: 264 SLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAF 323
SL + L + LA++ D+ L AQL+ +K LQ Q E+E R E
Sbjct: 737 SLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQA---EQEATVAR------EEQ 787
Query: 324 QRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQ 383
+R E L+Q AR QGLE S Q +A+ +Q P + +Q
Sbjct: 788 ERLEELRLEQEVAR-QGLEG-----------SLRVAEQAQEALEQQLPTLRHERSQLQEQ 835
Query: 384 KEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLA 430
QL + QELE+ RR + LER+ ++ HAGLA
Sbjct: 836 LAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLA 882
Score = 45.8 bits (107), Expect = 1e-04
Identities = 58/209 (27%), Positives = 97/209 (46%), Gaps = 11/209 (5%)
Query: 218 SESETGPME-EVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPD-SVPSLQNMGLLLDK- 274
SE + G ++ VER +V E+ G +D +R +A S+ S ++ L L K
Sbjct: 1696 SEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKA 1755
Query: 275 LAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQL 334
L D ++LQ +L A ++ L Q L E+ LRG + E + E +LQQL
Sbjct: 1756 LTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQL 1815
Query: 335 RARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQAL 394
R L+ + + L+ + Q ++ + ++ + L+ L + E+ E E AL
Sbjct: 1816 REVLRQRQEG-----EAAALNTVQKLQDERRLLQERLGSLQRALAQL-EAEKREVERSAL 1869
Query: 395 RQELER--QRRLLGSVQQDLERSLQDASR 421
R E +R RR L V+++ RS +D R
Sbjct: 1870 RLEKDRVALRRTLDKVEREKLRSHEDTVR 1898
Score = 42.0 bits (97), Expect = 0.002
Identities = 54/230 (23%), Positives = 92/230 (40%), Gaps = 41/230 (17%)
Query: 230 RQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRL----- 284
R + D ++ ++ + L P P +P+ + LL L +ENQ ++
Sbjct: 36 RDLAQDAQITSLPALIREIVTRNLSQPESPVLLPATEMASLL--SLQEENQLLQQELSRV 93
Query: 285 --LQAQLQAQKEEL------------QSLMHQPKGLEEENAQLRGALQQGEAFQRALESE 330
L AQ +A+++EL Q+L +P LE + RG ++Q +R L+ E
Sbjct: 94 EDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEP--RGLVRQSVELRRQLQEE 151
Query: 331 LQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAE 390
R +LQ + +G + + R Q L + K+ +LE +
Sbjct: 152 QASYRRKLQAYQ------------------EGQQRQAQLVQRLQGKILQYKKRCSELEQQ 193
Query: 391 AQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKL 440
ELE+QR QDLE +L A LA++ L ++L
Sbjct: 194 LLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQL 243
Score = 41.2 bits (95), Expect = 0.003
Identities = 67/282 (23%), Positives = 132/282 (46%), Gaps = 37/282 (13%)
Query: 275 LAKENQDIRLLQAQLQAQ----------KEELQSLMHQPKG----LEEENAQLRGALQ-Q 319
L KE +L+QA+ +AQ +E+LQ L + + LE E AQL+ LQ +
Sbjct: 964 LDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQRE 1023
Query: 320 GEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELS 379
E LE+E ++L + L+ + +G+ L+ ++ ++Q +E E +
Sbjct: 1024 QEELLARLEAEKEELSEEIAALQQE---RDEGLLLA--------ESEKQQALSLKESEKT 1072
Query: 380 FLKQKEQLEAEAQA-LRQELERQRRLLGSVQQDLERSLQDASRGD--PAHAGLAELGHRL 436
L +K + A + E+ERQ+R S +Q+ +RS +A + A E
Sbjct: 1073 ALSEKLMGTRHSLATISLEMERQKRDAQS-RQEQDRSTVNALTSELRDLRAQREEAAAAH 1131
Query: 437 AQKLQGLENWGQDPGVSAN-----ASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWK 491
AQ+++ L+ +D G + A + Q +++R+ +E ++ R+++ +
Sbjct: 1132 AQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGR 1191
Query: 492 H-KKEESGRERKKNWGGQEDREPAGRWKEG-RPRVEESGSKK 531
+++E+G R+ G ++RE R E R V+++ S++
Sbjct: 1192 EVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESER 1233
Score = 40.8 bits (94), Expect = 0.005
Identities = 74/334 (22%), Positives = 130/334 (38%), Gaps = 47/334 (14%)
Query: 207 GLGVLLFSGGLSESETGPMEEVERQVLPDPEVLEAVGDR----QDGLREQLQAPVPP-DS 261
GLG+ S GL +E+ +E+Q L ++ E + D+ +D ++Q+Q+ + D
Sbjct: 339 GLGL---STGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADL 395
Query: 262 VPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQP---------KGLE----- 307
+ +GL + +L K+N + + L + E L+SL Q +GL+
Sbjct: 396 SARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQTLRD 455
Query: 308 ---------EENAQLRGALQQGEAFQRALESELQQL-----RARLQGLEADCVRGPDGVC 353
E QL G+ + +A +L Q R G RGP C
Sbjct: 456 LAQAVLSDSESGVQLSGSERTADASNGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPAC 515
Query: 354 LSGGRGPQGDKAIRE--------QGPREQEPEL--SFLKQKEQLEAEAQALRQELERQRR 403
A+ + +G E +L + KQ E+E +AL ++L+R R
Sbjct: 516 SDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRD 575
Query: 404 LLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQK 463
Q E + ++ R A+ L+ LA LQ + ++ +A ++
Sbjct: 576 KTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEE 635
Query: 464 SHFQNSR-EWSGKEKWWDGQRDRKAEHWKHKKEE 496
Q R E ++ DG R R+ H++ E
Sbjct: 636 LRRQRDRLEEEQEDAVQDGARVRRELERSHRQLE 669
Score = 40.8 bits (94), Expect = 0.005
Identities = 68/243 (27%), Positives = 108/243 (44%), Gaps = 32/243 (13%)
Query: 227 EVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQN--MGLLLDKLAKENQDIRL 284
E +RQVL E L+A RQ + Q+ + V +L+ L L ++ E Q +L
Sbjct: 1760 EHDRQVLQ--ERLDAA--RQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQL 1815
Query: 285 LQAQLQAQKEE------LQSLMHQPKGLEEENAQLRGALQQGEAFQRA-------LESEL 331
+ Q Q+ E +Q L + + L+E L+ AL Q EA +R LE +
Sbjct: 1816 REVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDR 1875
Query: 332 QQLRARLQGLEADCVRG-PDGVCLSGGRG--------PQGDKAIREQGPREQEPELSFLK 382
LR L +E + +R D V LS +G + + A ++ ++ E ++ L+
Sbjct: 1876 VALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLE 1935
Query: 383 QKE---QLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHA-GLAELGHRLAQ 438
Q QLE +AQ + EL+++ L S Q ER+L+ R GL E L
Sbjct: 1936 QSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVRGLEEQVSTLKG 1995
Query: 439 KLQ 441
+LQ
Sbjct: 1996 QLQ 1998
Score = 40.4 bits (93), Expect = 0.006
Identities = 64/273 (23%), Positives = 104/273 (38%), Gaps = 45/273 (16%)
Query: 226 EEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQN-MGLLLDKLAKENQDIRL 284
+EV RQ L L Q+ L +QL P LQ + L +L+ Q++
Sbjct: 797 QEVARQGLEGS--LRVAEQAQEALEQQL--PTLRHERSQLQEQLAQLSRQLSGREQELEQ 852
Query: 285 LQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEAD 344
+ + Q Q E L+ + + L +E+A L L E R L E +LR + LE
Sbjct: 853 ARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGS 912
Query: 345 CVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLK-QKEQLEAEAQALRQELERQRR 403
E + +L+ L+ ++EQLEAE QAL E
Sbjct: 913 LF--------------------------EVQRQLAQLEARREQLEAEGQALLLAKETLTG 946
Query: 404 LLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQK 463
L ++Q + + + AS +AQKL E Q S +A H++
Sbjct: 947 ELAGLRQQIIATQEKASLDK----------ELMAQKLVQAEREAQ---ASLREQRAAHEE 993
Query: 464 SHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEE 496
+ RE + + +R + + ++EE
Sbjct: 994 DLQRLQREKEAAWRELEAERAQLQSQLQREQEE 1026
Score = 39.3 bits (90), Expect = 0.013
Identities = 40/170 (23%), Positives = 78/170 (45%), Gaps = 18/170 (10%)
Query: 278 ENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRAR 337
++ + L+ + L ++ ++Q + + + ++ LR L E+ +RALE +LQ+LR +
Sbjct: 517 DSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDK 576
Query: 338 LQG-LEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFL----KQKEQLEAEAQ 392
G ++A R Q ++ E RE+ L +Q E+L E +
Sbjct: 577 TDGAMQAH---------EDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQERE 627
Query: 393 ALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQG 442
L+ E RR ++++ E ++QD +R E HR ++L+G
Sbjct: 628 KLQAAQEELRRQRDRLEEEQEDAVQDGARVRRE----LERSHRQLEQLEG 673
Score = 37.0 bits (84), Expect = 0.065
Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 6/185 (3%)
Query: 276 AKENQDIRL--LQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQ 333
A+ + D RL +QA+L Q+E ++ + + ++ A L +LQ E+ RA + ++ +
Sbjct: 1566 ARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISK 1625
Query: 334 LRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQA 393
++A LE D R + + S R + + R Q L EA+AQA
Sbjct: 1626 MKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGL----SDREAQAQA 1681
Query: 394 LRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVS 453
L+ ++ +R + + R + A A + E L K++GL S
Sbjct: 1682 LQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSAS 1741
Query: 454 ANASK 458
N+++
Sbjct: 1742 LNSTR 1746
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 51.2 bits (121), Expect = 3e-06
Identities = 56/213 (26%), Positives = 97/213 (45%), Gaps = 17/213 (7%)
Query: 372 REQEPELSFLKQ-KEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLA 430
RE+E E+ K+ K++ E+E + R+E E+++R +++ ER + RG G
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKR-----EREKERKRE---RGKKEKKGER 90
Query: 431 ELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHW 490
+ R +K + + G K +K + S+E +E+ + +R+ + E
Sbjct: 91 KKEERERKKRRREKE--NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER- 147
Query: 491 KHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKK-EGKR-QGPKEPPRKSGSF 548
+ KKEE +ER++ + +R+ G +E R E KK E R + KE RK
Sbjct: 148 ERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207
Query: 549 HSSGEKQKQPRWREGTKDSHDPLPSWAELLRPK 581
K+K+ R +E KD +W E R K
Sbjct: 208 RKKERKKKEERKKERQKDRQ---TNWREKERGK 237
Score = 43.9 bits (102), Expect = 5e-04
Identities = 49/200 (24%), Positives = 90/200 (45%), Gaps = 19/200 (9%)
Query: 367 REQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAH 426
R++G +E+E E ++KE+ E E + +E ER+R G ++ ER ++ R
Sbjct: 48 RKEGKKERESE----RKKERREREKRKREREKERKRER-GKKEKKGERKKEERERKKRRR 102
Query: 427 AGLAELGH-RLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQR-D 484
+ G + +K + + G+ + +K + RE +E+ + +R +
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE 162
Query: 485 RKAEHWKH--KKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPP 542
RK K +KEE +E+++ + +R R KE R R E KKE K++ ++
Sbjct: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE-RERKERRERKKERKKKEERKKE 221
Query: 543 RKSGSFHSSGEKQKQPRWRE 562
R +K +Q WRE
Sbjct: 222 R---------QKDRQTNWRE 232
Score = 32.3 bits (72), Expect = 1.6
Identities = 35/173 (20%), Positives = 77/173 (44%), Gaps = 8/173 (4%)
Query: 358 RGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQ 417
RG + K R++ RE++ ++KE E E + R++ E++ R S ++ ER +
Sbjct: 81 RGKKEKKGERKKEERERKKRR---REKENKEGEEKEKRKKKEKKERGRTS-KEGKERERK 136
Query: 418 DASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEK 477
+ + + + R ++ + + V + ++ + RE + KE+
Sbjct: 137 EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196
Query: 478 WWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSK 530
+ +R + E K +K++ R++++ Q+DR+ R KE R + K
Sbjct: 197 KKERERKERRERKKERKKKEERKKER----QKDRQTNWREKERGKRERKERKK 245
Score = 32.0 bits (71), Expect = 2.1
Identities = 20/98 (20%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Query: 472 WSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKK 531
W + + + + + + E K ++ E +ER++ + +RE + + G+ E+ G +K
Sbjct: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKK--EKKGERK 91
Query: 532 EGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDSHD 569
+ +R+ K K EK+K+ +E + S +
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKE 129
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 50.1 bits (118), Expect = 7e-06
Identities = 60/350 (17%), Positives = 147/350 (42%), Gaps = 18/350 (5%)
Query: 216 GLSESETGPMEEVERQVLP-DPEVLEAVGD--RQDGLREQLQAPVPPDSVPSLQNMGLLL 272
G + G + E E QV + +V E G Q+G + + V + G
Sbjct: 80 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG--- 136
Query: 273 DKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQ 332
++ ++ +R + Q++ Q+ +++ Q + E + + G +++ E R E ++
Sbjct: 137 -QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMG 195
Query: 333 QLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQ 392
+ ++ E + + + + ++ +R+Q + E E KQ+EQ++ + +
Sbjct: 196 EQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEE 255
Query: 393 ALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGV 452
+R++ E+ R +++ E+ L+ + + E ++ ++ + + +
Sbjct: 256 QMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ-TGEQEEQMREQEEQMREQEEQMRE 314
Query: 453 SANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDRE 512
+ ++ Q + W KE+ W ++K + WK +++ +E + Q+ E
Sbjct: 315 QEEQMREQEEQMGKQEEQMWEQKEQMW----EQKEQMWKQEEQMGEQEEQM----QKQEE 366
Query: 513 PAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWRE 562
+ +E + EE K+E Q K+ + GE+++Q R +E
Sbjct: 367 QVRKQEEQMRKQEEQMRKQE--EQMRKQEEQMGEQKEQMGEQKEQMREQE 414
Score = 50.1 bits (118), Expect = 7e-06
Identities = 76/351 (21%), Positives = 145/351 (41%), Gaps = 41/351 (11%)
Query: 216 GLSESETGPMEEVERQVLP-DPEVLEAVGD--RQDGLREQLQAPVPPDSVPSLQNMGLLL 272
G + G + E E QV + +V E G Q+G + + V + G
Sbjct: 115 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG--- 171
Query: 273 DKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQ 332
++ ++ +R + Q++ Q+ ++ Q EE+ + +Q+ E E +++
Sbjct: 172 -QVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR 230
Query: 333 QLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQ 392
+ ++ E + + V + + ++ +REQ + +E E LKQKEQ E E Q
Sbjct: 231 KQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ 290
Query: 393 ALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGV 452
QE E+ R Q++ R ++ R Q+ Q E Q+ +
Sbjct: 291 TGEQE-EQMRE-----QEEQMREQEEQMR---------------EQEEQMRE---QEEQM 326
Query: 453 SANASKAWHQKSHFQNSREWSGKEKWWDGQRDR-KAEHWKHKKEESGRERKKNWGGQEDR 511
+ W QK W KE+ W + + E K+EE R++++ QE+
Sbjct: 327 GKQEEQMWEQKEQM-----WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEE- 380
Query: 512 EPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWRE 562
+ + ++ R + E+ G +KE + KE R+ GE+++Q R +E
Sbjct: 381 QMRKQEEQMRKQEEQMGEQKEQMGE-QKEQMREQE--EQMGEQKEQMRKQE 428
Score = 45.1 bits (105), Expect = 2e-04
Identities = 63/347 (18%), Positives = 137/347 (39%), Gaps = 24/347 (6%)
Query: 216 GLSESETGPMEEVERQVLP-DPEVLEAVGD--RQDGLREQLQAPVPPDSVPSLQNMGLLL 272
G + G + E E QV + +V E G Q+G + + V + G
Sbjct: 52 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG--- 108
Query: 273 DKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQ 332
++ ++ +R + Q++ Q+ +++ Q + E + + G +++ E R E +++
Sbjct: 109 -QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 167
Query: 333 QLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQ 392
+ +++ E V G+ + + + EQ + E E KQ+EQ+ + +
Sbjct: 168 EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227
Query: 393 ALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRL----AQKLQGLENWGQ 448
+R++ E+ VQ+ E+ + + + E ++ Q L+ E Q
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287
Query: 449 DPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQ 508
+ + Q+ + E Q + E + ++E+ G++ ++ W
Sbjct: 288 EEQTGEQEEQMREQEEQMREQEE----------QMREQEEQMREQEEQMGKQEEQMW--- 334
Query: 509 EDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQ 555
E +E KE + EE ++E + Q +E RK E+Q
Sbjct: 335 EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQ 381
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 50.1 bits (118), Expect = 7e-06
Identities = 70/286 (24%), Positives = 123/286 (43%), Gaps = 22/286 (7%)
Query: 277 KENQDIRLLQAQLQAQKEELQSLMHQ-PKGLEEENAQLRGALQQGEAFQRALESELQQLR 335
+E ++ R + L+ ++E+LQ Q + L+EE QLR +Q +R E + QQ
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Query: 336 ARLQGL----EADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSF-LKQKEQLEAE 390
R Q L E + + R Q ++ +Q REQE L+++++ E
Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
Query: 391 AQALRQELERQRR---LLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWG 447
Q LR+E E +RR L Q E+ L+ + E R Q+L+ +
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 448 QDPGVSANASKAWHQKSHFQNSRE------------WSGKEKWWDG-QRDRKAEHWKHKK 494
++ + + H++ H Q RE W +E+ + +++R+ + K +
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 495 EESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKE 540
EE RER +E RE R ++ R +E ++ KRQ +E
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEE 526
Score = 48.1 bits (113), Expect = 3e-05
Identities = 65/288 (22%), Positives = 116/288 (40%), Gaps = 46/288 (15%)
Query: 274 KLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQ 333
+L ++ ++ + LQ + Q +++EL+ + + L +E Q + L++ E +++ LE E Q
Sbjct: 1699 QLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ--LRRQERYRKILEEE--Q 1754
Query: 334 LRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEA--EA 391
LR + + R + D+ RE+ QE E L+ +E E
Sbjct: 1755 LRPEREEQQL--------------RRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800
Query: 392 QALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPG 451
+ LRQE E Q+ L Q+D R + L E RL Q+ +D
Sbjct: 1801 EQLRQEREEQQ--LRPQQRD------GKYRWEEEQLQLEEQEQRLRQE--------RDRQ 1844
Query: 452 VSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDR 511
A A +KS + W +E+ +R+RK ++++ +R + G + +
Sbjct: 1845 YRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904
Query: 512 EPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPR 559
E G + P G Q P R S + E++ Q R
Sbjct: 1905 EGKGHGRLLEP----------GTHQFASVPVRSSPLYEYIQEQRSQYR 1942
Score = 46.6 bits (109), Expect = 8e-05
Identities = 67/293 (22%), Positives = 129/293 (44%), Gaps = 25/293 (8%)
Query: 274 KLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQ 333
K ++ Q +R + Q Q ++E + + L+E Q L + E ++ LE E Q
Sbjct: 1596 KFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ---QLHRQERDRKFLEEEPQL 1652
Query: 334 LRA-RLQGLEADCVRG--PDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQ-LEA 389
R R Q L D R + L G Q + R++ RE+E +L +++ + L+
Sbjct: 1653 RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQE 1712
Query: 390 EAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQD 449
E Q RQELER+ R ++Q+ E+ + R + L E R ++ Q L +D
Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQ--EQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Query: 450 PGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQE 509
+ + ++ + RE +++ + DRK ++E+ +ER++ +
Sbjct: 1771 --------RKFREEEQLRQERE---EQQLRSQESDRKF----REEEQLRQEREEQQLRPQ 1815
Query: 510 DREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWRE 562
R+ RW+E + ++EE + +R + + S +++Q W+E
Sbjct: 1816 QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKS-RREEQELWQE 1867
Score = 45.4 bits (106), Expect = 2e-04
Identities = 74/326 (22%), Positives = 139/326 (42%), Gaps = 57/326 (17%)
Query: 274 KLAKENQDIRLLQA-----QLQAQKEELQSLM---HQPKGLEEENAQLRGALQQGEAFQR 325
+L ++ ++ RL Q QL+ ++EE + + + K LE+E + R +Q E +
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577
Query: 326 ALESELQQLRARL---------QGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEP 376
L+ E ++ + RL Q L+ + V R Q ++ REQ + +EP
Sbjct: 578 LLKREEERRQQRLKREQEERLEQRLKREEVE----------RLEQEER--REQRLKREEP 625
Query: 377 E----LSFLKQKEQLEAEAQALRQELE--RQRRLLGSVQQD-LERSLQDASRGDPAHAGL 429
E LK +EQ E Q LR+E + R++RL +++ LE+ L+ + L
Sbjct: 626 EEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQEL 685
Query: 430 AE-----LGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRD 484
AE R+ ++ + W + A SK + + + R +E + +R
Sbjct: 686 AEEEQEQARERIKSRIPKWQ-WQLESEADARQSKVYSRPRKQEGQRRRQEQE---EKRRR 741
Query: 485 RKAE---------HWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKR 535
R++E H + ++EE R+ W +E E + RP + E ++E +
Sbjct: 742 RESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLRE---QRERQL 798
Query: 536 QGPKEPPRKSGSFHSSGEKQKQPRWR 561
+ + R+ EK+++ R R
Sbjct: 799 RAEERQQREQRFLPEEEEKEQRRRQR 824
Score = 42.7 bits (99), Expect = 0.001
Identities = 61/303 (20%), Positives = 119/303 (39%), Gaps = 44/303 (14%)
Query: 277 KENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRA 336
+E+Q+ R Q Q + QK Q LEEE + R L A Q L E Q L+
Sbjct: 857 QEDQERRRSQEQRRDQKWRWQ--------LEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
Query: 337 RLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQ 396
+ L+ + + R QE E + ++++ + E Q LR+
Sbjct: 909 EEEELQRE----------------------EREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 397 ELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANA 456
E E++RR Q+ ER + + L ++ + + + ++ +
Sbjct: 947 EREKRRR------QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
Query: 457 SKAWHQKSHFQNSREWSGKEKWWDGQRDR-----KAEHWKHKKEESGRE-RKKNWGGQED 510
+ ++ + +EW + + D + + E K + +E R+ R++ QE+
Sbjct: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE 1060
Query: 511 REPAGRWKEGRPR--VEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDSH 568
+ G +E R R +E K+E +Q ++ R+ E+++Q R E +
Sbjct: 1061 EQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE 1120
Query: 569 DPL 571
+ L
Sbjct: 1121 EQL 1123
Score = 42.4 bits (98), Expect = 0.002
Identities = 69/307 (22%), Positives = 119/307 (38%), Gaps = 51/307 (16%)
Query: 274 KLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGA----LQQGEAFQRALES 329
K +E Q +R + + + +EE Q + + EE L+ L + E ++ LE
Sbjct: 1431 KFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490
Query: 330 ELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEA 389
E QQLR + + D+ REQ R QEPE FL++++QL
Sbjct: 1491 E-QQLRRQ-----------------------ERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 390 EAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQD 449
+ +RQR+ L QQ + R D E R ++ Q L +D
Sbjct: 1527 Q--------QRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578
Query: 450 PGVSANASKAWHQKSH------FQNSREWSGKEKWWDGQRDRK---AEHWKHKKEESGRE 500
K Q+ Q R G+++ +RDRK E ++EE
Sbjct: 1579 RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ-ERDRKFREDEQLLQEREEQQLH 1637
Query: 501 RKKNWGGQEDREPAGRWKEGRPRVEESGSKK-----EGKRQGPKEPPRKSGSFHSSGEKQ 555
R++ + EP R +E ++ +K + ++G ++ R+ E++
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEE 1697
Query: 556 KQPRWRE 562
+Q R +E
Sbjct: 1698 QQLRRQE 1704
Score = 39.3 bits (90), Expect = 0.013
Identities = 59/295 (20%), Positives = 123/295 (41%), Gaps = 40/295 (13%)
Query: 273 DKLAKENQDIRLLQA--QLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESE 330
++L +E ++ R Q + +K+ELQ + + L EE + R LQ+ E R E E
Sbjct: 1001 EQLLREEREKRRRQEWERQYRKKDELQQ--EEEQLLREEREKRR--LQERERQYRE-EEE 1055
Query: 331 LQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAE 390
LQQ +L G E + R QE E + K++E + E
Sbjct: 1056 LQQEEEQLLGEERET-------------------------RRRQELERQYRKEEELQQEE 1090
Query: 391 AQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDP 450
Q LR+E E++RR Q+ ER ++ L ++ + + ++
Sbjct: 1091 EQLLREEPEKRRR------QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
Query: 451 GVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQED 510
V + ++ + +E + + + + + + + ++E+ +ER++ + +E+
Sbjct: 1145 EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQY--REE 1202
Query: 511 REPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTK 565
E + ++ R R E+ S + + + KE + + G + +Q R E ++
Sbjct: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQ 1257
Score = 37.4 bits (85), Expect = 0.050
Identities = 61/293 (20%), Positives = 111/293 (37%), Gaps = 28/293 (9%)
Query: 363 DKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRG 422
+K R + RE+E EL FL+++EQL+ +A Q+L+ + +Q+D ER R
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERA--QQLQEEE---DGLQEDQERRRSQEQRR 870
Query: 423 DPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWH--QKSHFQNSREWSGKEKWWD 480
D E ++ + P + K Q+ + RE K + +
Sbjct: 871 DQKWRWQLE-----EERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQE 925
Query: 481 GQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEES--GSKKEGKRQGP 538
+R + E ++EE ++ +++RE R + + EE G + E +R+
Sbjct: 926 QERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE 985
Query: 539 KEPPRKSGS---------FHSSGEKQKQPRWREGTKDSHDPLPSWAELLRP-----KYRA 584
+E + EK+++ W + + +LLR + +
Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE 1045
Query: 585 PQGCSGVDECARQEGLTFFGTELAPVRQQELASLLRTYLARLPWAGQLTKELP 637
+ +E +QE G E R+QEL R QL +E P
Sbjct: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Score = 35.0 bits (79), Expect = 0.25
Identities = 65/299 (21%), Positives = 124/299 (41%), Gaps = 14/299 (4%)
Query: 266 QNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQR 325
Q GL +K A+ + LLQ + Q+E+ + + + LEEE Q R +Q + +
Sbjct: 91 QATGLDEEKRARCDGKESLLQDR--RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL 148
Query: 326 ALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLK--Q 383
A E + + RL+ + D R + + Q + + R +E +L K +
Sbjct: 149 AEGEEQSEKQERLE--QRDRQRRDEELWR------QRQEWQEREERRAEEEQLQSCKGHE 200
Query: 384 KEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGL 443
E+ E Q R+EL RR +Q R QD + + L ++ + L
Sbjct: 201 TEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKL 260
Query: 444 ENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKK 503
+ + +K Q R +E+ QR R+ + + K+EE RE+++
Sbjct: 261 QEEEPQRQRELQEEEEQLRKLERQELRR-ERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Query: 504 NWGGQED-REPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWR 561
Q++ RE +E + R E+ +++ R+ +E R+ E++++ + R
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Score = 35.0 bits (79), Expect = 0.25
Identities = 65/352 (18%), Positives = 135/352 (38%), Gaps = 59/352 (16%)
Query: 277 KENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRA 336
+ Q +R Q + Q+EE H+ + E R ++ + +R E+E +
Sbjct: 414 RREQQLRREQQLRREQEEERHEQKHEQE--RREQRLKREQEERRDWLKREEETERHEQER 471
Query: 337 RLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQ 396
R Q L+ D +E+ RE+ +L +++EQ E Q LR+
Sbjct: 472 RKQQLKRD----------------------QEEERRERWLKLEEEERREQQERREQQLRR 509
Query: 397 ELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANA 456
E E +R +Q L+R ++ RL Q+L+ + ++
Sbjct: 510 EQEERR------EQRLKRQEEE---------------ERLQQRLRSEQQLRREQEERREQ 548
Query: 457 SKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGR 516
++ + R ++ + +RD+ K+EE R+++ +E E +
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLL-----KREEERRQQRLKREQEERLEQRLK 603
Query: 517 WKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDSHDPLPSWAE 576
+E +E ++ KR+ P+E R+ E+Q++ R ++ ++ + +
Sbjct: 604 REEVERLEQEERREQRLKREEPEEERRQQ---LLKSEEQEERRQQQLRREQQERREQRLK 660
Query: 577 LLRPKYRAPQGCSGVDECARQEGLTFFGTELAPVRQQELASLLRTYLARLPW 628
+ R Q E R+E ELA Q++ +++ + + W
Sbjct: 661 REEEEERLEQRLKREHEEERRE------QELAEEEQEQARERIKSRIPKWQW 706
Score = 33.1 bits (74), Expect = 0.94
Identities = 61/258 (23%), Positives = 100/258 (38%), Gaps = 41/258 (15%)
Query: 361 QGDKAIRE-QGPREQEPELSFLKQKEQLEAE--AQALRQELERQRRLLGSVQQDLERSLQ 417
QG K + E Q R QE E FLK+++QL + Q LRQ+ +R+ R +Q L R +
Sbjct: 1372 QGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFR---EEEQQLSRQER 1428
Query: 418 DAS-RGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKE 476
D R + E + ++ Q L + + ++ RE ++
Sbjct: 1429 DRKFREEEQQVRRQERERKFLEEEQQLRQ---------ERHRKFREEEQLLQERE---EQ 1476
Query: 477 KWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQ 536
+ +RDRK + + R+RK +EP R +EE +RQ
Sbjct: 1477 QLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE------RKFLEEEQQLHRQQRQ 1530
Query: 537 GPKEPPRKSGSFHSSGEKQKQPRWREGTKDSHDPLPSWAELLRPKYRAPQGCSGVDECAR 596
+ G++++Q R R+ ++ E LR + Q +R
Sbjct: 1531 RKFLQEEQQLRRQERGQQRRQDRDRKFREE---------EQLRQEREEQQ-------LSR 1574
Query: 597 QEGLTFFGTELAPVRQQE 614
QE F E VR+QE
Sbjct: 1575 QERDRKFRLEEQKVRRQE 1592
Score = 31.6 bits (70), Expect = 2.7
Identities = 62/337 (18%), Positives = 129/337 (38%), Gaps = 48/337 (14%)
Query: 219 ESETGPMEEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKE 278
E ET +E+ERQ + E+ + EQL P + ++ ++
Sbjct: 1067 ERETRRRQELERQYRKEEELQQE--------EEQLLREEPEKRRRQERERQCREEEELQQ 1118
Query: 279 NQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQ-QLRAR 337
++ L + + + +++EL+ + + +++E QL L++ +R E E Q +
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQL---LREEPEKRRRQELERQYREEEE 1175
Query: 338 LQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQE 397
LQ E +R EQ R QE E + +++E+L+ + + R
Sbjct: 1176 LQQEEEQLLR-------------------EEQEKRRQERERQY-REEEELQRQKRKQRYR 1215
Query: 398 LERQRR-LLGSVQQDLERSLQD-----ASRGDPAHAGLAELGHRLAQKLQGLENWGQDPG 451
E QR L + + E +++D R + L + R Q Q L++ +
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQ- 1274
Query: 452 VSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDR 511
++ Q R W +++ + + + E K K + +++ +E+R
Sbjct: 1275 ---------QERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREER 1325
Query: 512 EPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSF 548
E R +E + E + + + P + F
Sbjct: 1326 EEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 49.7 bits (117), Expect = 1e-05
Identities = 77/381 (20%), Positives = 153/381 (40%), Gaps = 66/381 (17%)
Query: 227 EVERQVLPDPEVLEAVGDRQDGLR------EQLQAPVPPDSVPSLQNMGLLL-------- 272
E+ R + D E+ E + Q+ LR ++Q V D L+ LLL
Sbjct: 205 ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVK-DLKRKLERAQLLLPQQQLQVE 263
Query: 273 -DKLAKENQDIRL-LQAQL----------QAQKEEL----QSLMHQPKGLEEENAQLRGA 316
D+L KE Q + LQAQ+ Q Q+E++ + + Q + + E+ ++R
Sbjct: 264 ADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQ 323
Query: 317 ---LQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPRE 373
+ + E E ++++ ++ E + + + + ++ IREQ +
Sbjct: 324 EEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383
Query: 374 QEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELG 433
QE E +Q+E++ + + ++++ RQ + + + + ++ R + L E+
Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM 443
Query: 434 HRLAQKLQGLEN----------------WGQDPGVSANASKAWHQ--------KSHFQNS 469
+KL+ +E Q+ + K W Q K Q
Sbjct: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
Query: 470 REWSGKEKWWDGQRDRKAEHWK-HKKEESGRERKKNWGGQEDR--EPAGRWKEGRPRVEE 526
+ W +EK W+ + + + K ++EE RE++ QE++ E R +E R+ +
Sbjct: 504 KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
Query: 527 SGSKKE-----GKRQGPKEPP 542
G K E G+ G + P
Sbjct: 564 LGQKAELLGGAGRESGSQRLP 584
Score = 48.1 bits (113), Expect = 3e-05
Identities = 58/239 (24%), Positives = 104/239 (43%), Gaps = 26/239 (10%)
Query: 350 DGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQ 409
D + L R D+ ++E+ QE +K +++ + L+++LER + LL Q
Sbjct: 200 DALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQ 259
Query: 410 QDLE-----RSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQ-- 462
+E + LQ S A EL + L Q+ Q + W Q+ + K Q
Sbjct: 260 LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQ-QEEKMWRQEEKIQEQEEKMCEQEL 318
Query: 463 KSHFQNSREWSGKEKWWDGQ---RDRKAEHWKHKK-----EESGRERKKNWGGQEDR--- 511
K Q + W +EK + + R+++ + W+ ++ EE RE+++ QE++
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE 378
Query: 512 --EPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEK---QKQPRWREGTK 565
E +E R EE ++E KRQ ++ R+ EK Q++ WR+ K
Sbjct: 379 QDEKIQEQEEEMWRQEEKIREQEEKRQ--EKMWRQEKKMREQDEKIREQEEEMWRQEEK 435
Score = 38.1 bits (87), Expect = 0.029
Identities = 54/315 (17%), Positives = 134/315 (42%), Gaps = 34/315 (10%)
Query: 268 MGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRAL 327
MG ++KL KE + L + EEL+ E+NA+L+ L+ E+ + +
Sbjct: 188 MGTYIEKLTKERDALSLELYRNTITDEELK----------EKNAELQEKLRLVESEKSEI 237
Query: 328 ESELQQLRARLQGLEADCVRGPDGVCLSGGR-GPQGDKAIREQGPREQEPELSFL---KQ 383
+ ++ L+ +L+ A + + + R G + + + +E EL L +Q
Sbjct: 238 QLNVKDLKRKLE--RAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQ 295
Query: 384 KEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGL 443
+E++ + + ++++ E+ +++ E+ + + + E ++ ++ + +
Sbjct: 296 EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKI 355
Query: 444 ENWGQDPGVSANASKAWHQKSHF--QNSREWSGKEKWW-------DGQRDRKAEHWKHKK 494
Q+ + K W Q+ Q+ + +E+ W + + R+ + W+ +K
Sbjct: 356 RE--QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413
Query: 495 -----EESGRERKKNWGGQED--REPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGS 547
+E RE+++ QE+ RE ++ ++ E K + + + +E K
Sbjct: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473
Query: 548 FHSSGEKQKQPRWRE 562
++Q++ WR+
Sbjct: 474 QEEKIQEQEEKTWRQ 488
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 47.8 bits (112), Expect = 4e-05
Identities = 71/320 (22%), Positives = 128/320 (40%), Gaps = 51/320 (15%)
Query: 272 LDKLAKENQDIRLLQAQLQAQKEELQSL-MHQPKGLEEENAQLRGALQQGEAFQRALESE 330
L K A E Q I+ + Q ++E + ++ + + K LE +N R L+ + F L++
Sbjct: 709 LIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSR-MLEDRDLFVMRLKAA 767
Query: 331 LQQL-RARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLE- 388
Q + +L+ E + ++ + R++E +++ ++KE+ E
Sbjct: 768 RQSVYEEKLKQFEERLAE------------ERHNRLEERKRQRKEERRITYYREKEEEEQ 815
Query: 389 --AEAQALRQELERQRRLLGSVQQDLE------RSLQDASRGDPAHAGLAELGHRLAQKL 440
AE Q L++ ER+R +++L + L++ R E R ++
Sbjct: 816 RRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEE 875
Query: 441 QGL---------ENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWK 491
+ L WG ++ W + + EK W + + + E
Sbjct: 876 RRLGDSSLSRKDSRWG-----DRDSEGTWRKGPEADSEWRRGPPEKEW-RRGEGRDEDRS 929
Query: 492 HKKEESGRERKKNWGGQEDREPAGRWKEGR-PRVEESGSKKEGKRQGPKEPPRKSGSFHS 550
H+++E ER + G EDREP+ R + R PR G R+GP+E F
Sbjct: 930 HRRDE---ERPRRLGDDEDREPSLRPDDDRVPR--RGMDDDRGPRRGPEE-----DRFSR 979
Query: 551 SGEKQKQPRWREGTKDSHDP 570
G +P WR T D P
Sbjct: 980 RGADDDRPSWR-NTDDDRPP 998
Score = 42.4 bits (98), Expect = 0.002
Identities = 70/340 (20%), Positives = 140/340 (41%), Gaps = 53/340 (15%)
Query: 277 KENQDIRLLQAQLQAQKEELQSL--MHQPKGLEEENAQLRGALQQGEAF--QRALESELQ 332
KE+Q I + ++ +KE L+SL + + LE+ A+L+ + E Q A E E +
Sbjct: 563 KEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKE 622
Query: 333 QLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQ 392
++ + ++ VR G + K I + E +P+ KQ EQLE E +
Sbjct: 623 RILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKK 682
Query: 393 ALRQELERQRRLLGSVQQ-------DLERSLQDASRGDPAHAGLAELGHRLA----QKLQ 441
L++ L+ Q + + ++ L +S + R + R+ ++ +
Sbjct: 683 ELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREK 742
Query: 442 GLENWG------QDPGVSANASKAWHQKSHFQNSREWSGK----------EKWWDGQRDR 485
LE+ +D + KA Q + + +++ + E+ + +R
Sbjct: 743 ALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEER 802
Query: 486 KAEHWKHKKEESGRERKKNW-GGQEDREPAGR---------WKEGRPRVEESGSKKEGK- 534
+ +++ K+EE R ++ +E+RE A R ++E ++EE KK +
Sbjct: 803 RITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRE 862
Query: 535 -----RQGPKEPPRKSGSFHSS------GEKQKQPRWREG 563
R+ +E R+ G S G++ + WR+G
Sbjct: 863 LEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKG 902
Score = 30.8 bits (68), Expect = 4.7
Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 13/85 (15%)
Query: 475 KEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGK 534
+E+ WD +++R ++ ++ + ER+++ DRE R RPR E G
Sbjct: 1199 EEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFR----RPRDE------GGW 1248
Query: 535 RQGPKEPPRKSGSFHSSGEKQKQPR 559
R+GP E +S S+ S + + R
Sbjct: 1249 RRGPAE---ESSSWRDSSRRDDRDR 1270
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 47.8 bits (112), Expect = 4e-05
Identities = 68/333 (20%), Positives = 132/333 (39%), Gaps = 45/333 (13%)
Query: 276 AKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQG-EAFQRAL--ESELQ 332
A ++++ + + + A+ + + Q EEN ++ G ++ E L ++E+
Sbjct: 578 AFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVS 637
Query: 333 QLRARLQGLEADCVRGP-DGVCLSGGRGPQG------DKAIREQG------PREQEPELS 379
+ +A+ G D G DG C G G + +K +++G P E E EL+
Sbjct: 638 EGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELA 697
Query: 380 FLK-----------QKEQLEAEAQALRQELER--QRRLLGSVQQDLERSLQDASRGDPAH 426
+ QKE+ + + QE+E + +++ +R ++ G+
Sbjct: 698 EKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKE 757
Query: 427 AGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQ---- 482
G E +K +G + G + Q + E G+EK G+
Sbjct: 758 EGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGG 817
Query: 483 --RDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSK-------KEG 533
+ K E + ++E G E + G E+ E G +EG + EE G + +EG
Sbjct: 818 EVEEGKGEREEEEEEGEGEEEE---GEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEG 874
Query: 534 KRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKD 566
+ +G +E G GE +++ EG ++
Sbjct: 875 EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEE 907
Score = 43.1 bits (100), Expect = 0.001
Identities = 60/301 (19%), Positives = 117/301 (38%), Gaps = 40/301 (13%)
Query: 290 QAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGP 349
+ +K++ + M +P E+E A+ ++ Q E E + R Q +E
Sbjct: 676 KGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEME------- 728
Query: 350 DGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSV- 408
GG G+ E+G RE+E E ++E E + R++ E +R+
Sbjct: 729 -----EGGEEEHGEGE-EEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAG 782
Query: 409 ---------------QQDLERSLQDASRGDPAHAGLAELG----HRLAQKLQGLENWGQD 449
+++ E ++ G G E G ++ +G E G+
Sbjct: 783 KEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEG 842
Query: 450 PGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGR----ERKKNW 505
+ + + E G+E+ +G+ + + E + + EE G E +
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 902
Query: 506 GGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTK 565
G+E+ E G +EG + EE G +EG+ +G +E G ++++ W EG +
Sbjct: 903 EGEEEGEGEGEEEEGEGKGEEEG--EEGEGEGEEEEGEGEGEDGEGEGEEEEGEW-EGEE 959
Query: 566 D 566
+
Sbjct: 960 E 960
Score = 41.6 bits (96), Expect = 0.003
Identities = 74/392 (18%), Positives = 149/392 (38%), Gaps = 34/392 (8%)
Query: 219 ESETGPMEEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKE 278
E E G +E +++ E G+ ++G RE+ + +K +
Sbjct: 714 EREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEE------------------EKEGEG 755
Query: 279 NQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARL 338
++ + + + +KEE + + G EE+ + G +GE + E ++ +
Sbjct: 756 KEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE-EGDQGEGEEEETEGRGEEKEEGGEV 814
Query: 339 QGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQEL 398
+G E + +G G G + + E+ +E E ++E E E + +E
Sbjct: 815 EGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEG 874
Query: 399 E---RQRRLLGSVQQDLE-RSLQDASRGDPAHAGLAELGHRLAQ---KLQGLENWGQDPG 451
E + G +++ E ++ G+ G E + + +G E G+
Sbjct: 875 EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934
Query: 452 VSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDR 511
+ + EW G+E+ +G+ + + E + E G E + G+E+
Sbjct: 935 EEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEE 994
Query: 512 EPAGRWKEGRPRVEESG---SKKEGKRQGPKEPPRKSG-SFHSSGEKQKQPRWREGTKDS 567
+EG E G ++EG+ +G E G GE++ + R +EG +
Sbjct: 995 GEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEE 1054
Query: 568 HDPLPSWAELLRPKYRAPQGCSGVDECARQEG 599
+ E KY+ +G +E RQ+G
Sbjct: 1055 NRRNREEEEEEEGKYQE----TGEEENERQDG 1082
Score = 32.7 bits (73), Expect = 1.2
Identities = 55/269 (20%), Positives = 105/269 (39%), Gaps = 19/269 (7%)
Query: 290 QAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGP 349
+ ++EE + + +G EE + ++GE + E E + +G
Sbjct: 841 EGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 900
Query: 350 DGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQ 409
+G G G +G++ E E+ E ++E+ E E + E E + +
Sbjct: 901 EGEGEEEGEG-EGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEE 959
Query: 410 QDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNS 469
++ E ++ G+ G E G + +G E G++ G + ++ +
Sbjct: 960 EEGEGEGEEEGEGE-GEEGEGE-GEEEEGEGEGEEEEGEEEGEEEGEGE---EEGEGEGE 1014
Query: 470 REWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGS 529
E G+ + + + E + + EE G ER+K G+E+R R E
Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENR-----------RNREEEE 1063
Query: 530 KKEGKRQ--GPKEPPRKSGSFHSSGEKQK 556
++EGK Q G +E R+ G + K K
Sbjct: 1064 EEEGKYQETGEEENERQDGEEYKKVSKIK 1092
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 47.4 bits (111), Expect = 5e-05
Identities = 45/169 (26%), Positives = 82/169 (48%), Gaps = 16/169 (9%)
Query: 265 LQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQ------ 318
LQ + LL + + Q RLLQ + + ++ + + L +G E Q R ++Q
Sbjct: 361 LQELELLQEA---QRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELK 417
Query: 319 -QGEAFQRALESELQQLRARLQG---LEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQ 374
+ A QR EL++++ RLQ LE R + V ++ R + ++ +Q + +
Sbjct: 418 EEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLK 477
Query: 375 EPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGD 423
E + ++++ +Q E + L+QE+ +Q R L QQ LE Q+ R D
Sbjct: 478 EEQERYIERAQQ---EKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRAD 523
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 47.0 bits (110), Expect = 6e-05
Identities = 49/237 (20%), Positives = 100/237 (42%), Gaps = 10/237 (4%)
Query: 308 EENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIR 367
E + Q + ++ + +R SE + R + + E D R D R Q D+ +
Sbjct: 231 ERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR--RQKERERQTDRKRQ 288
Query: 368 EQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHA 427
+ R++E E +Q+E+ + ++E ER+R + ER Q + D
Sbjct: 289 RRTERDRETERKRERQRERERERERNRKRERERER--------ERERERQRETERDREKE 340
Query: 428 GLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKA 487
+ + + G++ A + ++ Q++RE +E+ D R ++
Sbjct: 341 RERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKER 400
Query: 488 EHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRK 544
E K + RE +K ++DRE + GR R ++ G +++ +RQ ++ R+
Sbjct: 401 ERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQ 457
Score = 43.9 bits (102), Expect = 5e-04
Identities = 55/223 (24%), Positives = 87/223 (39%), Gaps = 33/223 (14%)
Query: 358 RGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQ-------ELERQRRLLGSVQQ 410
R + ++ Q RE+E E + +++E+ E E + RQ E ER+R+ +
Sbjct: 293 RDRETERKRERQRERERERERNRKRERER-ERERERERQRETERDREKERERKRKRQTEM 351
Query: 411 DLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSR 470
D ER+ Q G R A++ + E + + Q R
Sbjct: 352 DRERNRQTGREG-----------RRQAERERERERERDRQSAREREERERDRDRDRQKER 400
Query: 471 EWSGKEKWWDGQRDRKAEHWKHKKEES------GRERKKNWGGQEDREPAGRWKEGRPRV 524
E EK DGQR+ + + + K ES GRER+K G + DRE + GR R
Sbjct: 401 ERQ-TEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQR- 458
Query: 525 EESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQP-RWREGTKD 566
K+ P +SG S + + RW+ +D
Sbjct: 459 -----KRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPED 496
Score = 40.8 bits (94), Expect = 0.005
Identities = 48/253 (18%), Positives = 98/253 (38%), Gaps = 10/253 (3%)
Query: 325 RALESELQQLRARLQGLEADCVRGPDGVC---LSGGRGPQGDKAIREQGPREQEPELSFL 381
R E E + + R + E + RG D R +K Q RE++ +
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
Query: 382 KQKEQLEAEAQALRQELERQRRLLGSVQ-------QDLERSLQDASRGDPAHAGLAELGH 434
+QKE+ + + R+E ERQR + ++ ER + + + E
Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
Query: 435 RLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKK 494
+ + + + ++ + ++ R+ ++K + Q DRK + +
Sbjct: 235 QRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERD 294
Query: 495 EESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEK 554
E+ R+R++ + +RE + + R R E ++E +R KE RK +
Sbjct: 295 RETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354
Query: 555 QKQPRWREGTKDS 567
+ + REG + +
Sbjct: 355 RNRQTGREGRRQA 367
Score = 37.0 bits (84), Expect = 0.065
Identities = 38/178 (21%), Positives = 72/178 (40%), Gaps = 8/178 (4%)
Query: 398 LERQRRLLGSVQQDLERSLQDASR---GDPAHAGLAELGHRLAQKLQGLENWGQDPGVSA 454
L+ RR GS + R L A + GD + R +K Q D
Sbjct: 24 LDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERE--TDRKRER 81
Query: 455 NASKAWHQKSHFQNSREWSG---KEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDR 511
K H+K R+ +E+ D +RDR+ E +++++E RE ++ DR
Sbjct: 82 RREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDR 141
Query: 512 EPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDSHD 569
+ G+ + R R E +++ R+ ++ R + +++ R RE ++ +
Sbjct: 142 QTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN 199
Score = 34.3 bits (77), Expect = 0.42
Identities = 21/88 (23%), Positives = 44/88 (50%)
Query: 480 DGQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPK 539
D + +RK E + ++ E R RK+ + +RE + + R R +E K++ + + +
Sbjct: 294 DRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDR 353
Query: 540 EPPRKSGSFHSSGEKQKQPRWREGTKDS 567
E R++G ++++ R RE + S
Sbjct: 354 ERNRQTGREGRRQAERERERERERDRQS 381
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 46.2 bits (108), Expect = 1e-04
Identities = 80/317 (25%), Positives = 132/317 (41%), Gaps = 66/317 (20%)
Query: 271 LLDKLAKENQDIRLLQAQLQAQKEELQSL---MHQPKG-LEEENAQLRGALQQGEAFQRA 326
LL++ KE +DI +L+A+ + + EL++L HQ +G L++ +L Q+ E+ ++
Sbjct: 457 LLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKS 516
Query: 327 LE---SELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPEL---SF 380
E +E+ L+ +LQ + GR + + +Q + Q+ L S
Sbjct: 517 RELRIAEITHLQQQLQESQQML-----------GRLIPEKQILNDQLKQVQQNSLHRDSL 565
Query: 381 LKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKL 440
+ K LEA+ A RQ L Q L V+++ LQ+ D + L EL
Sbjct: 566 VTLKRALEAKELA-RQHLRDQ---LDEVEKETRSKLQEI---DIFNNQLKEL-------- 610
Query: 441 QGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGR- 499
+ H K Q + E+ +++RK + +KEE+ R
Sbjct: 611 -----------------REIHNKQQLQKQKSMEA-ERLKQKEQERKIIELEKQKEEAQRR 652
Query: 500 --ERKKNW-----GGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGS-FHSS 551
ER K W E + P +E + + EES KK+G+ +G +E K G FH
Sbjct: 653 AQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQH 712
Query: 552 GEKQK---QPRWREGTK 565
E K Q W K
Sbjct: 713 QEPAKPAVQAPWSTAEK 729
Score = 31.2 bits (69), Expect = 3.6
Identities = 51/193 (26%), Positives = 90/193 (46%), Gaps = 23/193 (11%)
Query: 239 LEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQ----DIRLLQAQLQAQKE 294
LEA+ D++ L +LQ D L ++ K + +I LQ QLQ ++
Sbjct: 482 LEALNDKKHQLEGKLQ-----DIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQ 536
Query: 295 ELQSLMHQPKGLEEENAQLR-GALQQGE--AFQRALESE---LQQLRARLQGLEADCVRG 348
L L+ + + L ++ Q++ +L + +RALE++ Q LR +L +E +
Sbjct: 537 MLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSK 596
Query: 349 PDGVCLSGGRGPQGDKAIREQGPREQEP-ELSFLKQKEQ----LEAEAQ---ALRQELER 400
+ + + + + +Q ++Q+ E LKQKEQ +E E Q A R+ ER
Sbjct: 597 LQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQER 656
Query: 401 QRRLLGSVQQDLE 413
++ L VQQ+ E
Sbjct: 657 DKQWLEHVQQEDE 669
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 46.2 bits (108), Expect = 1e-04
Identities = 80/317 (25%), Positives = 132/317 (41%), Gaps = 66/317 (20%)
Query: 271 LLDKLAKENQDIRLLQAQLQAQKEELQSL---MHQPKG-LEEENAQLRGALQQGEAFQRA 326
LL++ KE +DI +L+A+ + + EL++L HQ +G L++ +L Q+ E+ ++
Sbjct: 457 LLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKS 516
Query: 327 LE---SELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPEL---SF 380
E +E+ L+ +LQ + GR + + +Q + Q+ L S
Sbjct: 517 RELRIAEITHLQQQLQESQQML-----------GRLIPEKQILNDQLKQVQQNSLHRDSL 565
Query: 381 LKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKL 440
+ K LEA+ A RQ L Q L V+++ LQ+ D + L EL
Sbjct: 566 VTLKRALEAKELA-RQHLRDQ---LDEVEKETRSKLQEI---DIFNNQLKEL-------- 610
Query: 441 QGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGR- 499
+ H K Q + E+ +++RK + +KEE+ R
Sbjct: 611 -----------------REIHNKQQLQKQKSMEA-ERLKQKEQERKIIELEKQKEEAQRR 652
Query: 500 --ERKKNW-----GGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGS-FHSS 551
ER K W E + P +E + + EES KK+G+ +G +E K G FH
Sbjct: 653 AQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQH 712
Query: 552 GEKQK---QPRWREGTK 565
E K Q W K
Sbjct: 713 QEPAKPAVQAPWSTAEK 729
Score = 31.2 bits (69), Expect = 3.6
Identities = 51/193 (26%), Positives = 90/193 (46%), Gaps = 23/193 (11%)
Query: 239 LEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQ----DIRLLQAQLQAQKE 294
LEA+ D++ L +LQ D L ++ K + +I LQ QLQ ++
Sbjct: 482 LEALNDKKHQLEGKLQ-----DIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQ 536
Query: 295 ELQSLMHQPKGLEEENAQLR-GALQQGE--AFQRALESE---LQQLRARLQGLEADCVRG 348
L L+ + + L ++ Q++ +L + +RALE++ Q LR +L +E +
Sbjct: 537 MLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSK 596
Query: 349 PDGVCLSGGRGPQGDKAIREQGPREQEP-ELSFLKQKEQ----LEAEAQ---ALRQELER 400
+ + + + + +Q ++Q+ E LKQKEQ +E E Q A R+ ER
Sbjct: 597 LQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQER 656
Query: 401 QRRLLGSVQQDLE 413
++ L VQQ+ E
Sbjct: 657 DKQWLEHVQQEDE 669
>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
Length = 1194
Score = 46.2 bits (108), Expect = 1e-04
Identities = 58/237 (24%), Positives = 92/237 (38%), Gaps = 60/237 (25%)
Query: 239 LEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQL--------- 289
L +G +D L+ QL +P + + + L ++L + ++I L+A+
Sbjct: 60 LRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEH 119
Query: 290 -------------------QAQK-----------EELQSLMHQPKGLEEE-NAQLRGALQ 318
QAQ + L+SL K L+E+ +LR AL+
Sbjct: 120 LECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALE 179
Query: 319 QGEAFQRALESELQ-------QLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIR---- 367
+ + LE Q QL R GLE G DG L+ G GP GD R
Sbjct: 180 RVAVLEEELELSNQETLNLREQLSRRRSGLEEPGKDG-DGQTLANGLGPGGDSNRRTAEL 238
Query: 368 EQGPREQEPELSFLKQK--------EQLEAEAQALRQELERQRRLLGSVQQDLERSL 416
E+ Q E+ L+++ QLE E +EL + +Q+DL+ +L
Sbjct: 239 EEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDLKEAL 295
Score = 34.7 bits (78), Expect = 0.32
Identities = 58/264 (21%), Positives = 102/264 (38%), Gaps = 50/264 (18%)
Query: 219 ESETGPMEEVERQVLPDPEVL-EAVGDRQDGLREQLQ-APVPPDSVPSLQNMGLLLDKLA 276
E+E E + RQ L E + D + L++ LQ A P+ L L+K
Sbjct: 330 ENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAE 389
Query: 277 KEN----QDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQ 332
+ + + +R L+AQL+ + +ELQ + K ++ N +L + + + E
Sbjct: 390 ERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVD--KLLSESNERLQL 447
Query: 333 QLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQ 392
L+ R+ LE ++ E+ ++ + L KEQL AE +
Sbjct: 448 HLKERMGALEE-------------------KNSLSEEIANMKKLQDELLLNKEQLLAEME 488
Query: 393 ALRQELER---------QRRLLGS---VQQDLERSLQDASRGDPAHAGLAELGHRLAQKL 440
++ E+++ R L GS ++ +L + DP AG G R
Sbjct: 489 RMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAPTLPSGAHLDPYVAGSGRAGKR----- 543
Query: 441 QGLENWGQDPGVSANASKAWHQKS 464
G+ GV SK W + +
Sbjct: 544 ------GRWSGVKEEPSKDWERSA 561
>gi|117168269 coiled-coil domain containing 33 isoform 2 [Homo
sapiens]
Length = 367
Score = 45.8 bits (107), Expect = 1e-04
Identities = 45/174 (25%), Positives = 83/174 (47%), Gaps = 19/174 (10%)
Query: 255 APVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLR 314
AP DS + N + K+A++ +R + L+ + L+S + Q EEE Q +
Sbjct: 15 APGLIDSFSEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQ---EEEEGQGK 71
Query: 315 GALQQGEAF--QRALESEL--QQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQG 370
+ Q Q+ L SEL ++LR R+Q L+ + +R D + + + Q
Sbjct: 72 ASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDR---------EKELLLLYQA 122
Query: 371 PREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDP 424
Q+P+ + LKQ + + +AL + + Q +++ +++ LE LQD S+ P
Sbjct: 123 ---QQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPP 173
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.132 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,209,055
Number of Sequences: 37866
Number of extensions: 1915929
Number of successful extensions: 13551
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 189
Number of HSP's successfully gapped in prelim test: 582
Number of HSP's that attempted gapping in prelim test: 9600
Number of HSP's gapped (non-prelim): 3019
length of query: 731
length of database: 18,247,518
effective HSP length: 110
effective length of query: 621
effective length of database: 14,082,258
effective search space: 8745082218
effective search space used: 8745082218
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.