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Search of human proteins with 19923592
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
(747 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens] 1520 0.0
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi... 788 0.0
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap... 437 e-122
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap... 437 e-122
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap... 437 e-122
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap... 437 e-122
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap... 437 e-122
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap... 437 e-122
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap... 437 e-122
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [... 218 2e-56
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ... 218 2e-56
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [... 218 2e-56
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [... 213 7e-55
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [... 213 7e-55
gi|4505531 oxysterol binding protein [Homo sapiens] 114 3e-25
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa... 110 4e-24
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa... 110 4e-24
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens] 102 1e-21
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [... 89 2e-17
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H... 89 2e-17
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens] 82 2e-15
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [... 80 7e-15
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [... 80 7e-15
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [... 75 2e-13
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [... 75 2e-13
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [... 75 2e-13
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [... 75 2e-13
gi|14165452 alpha 3 type IV collagen binding protein isoform 2 [... 67 8e-11
gi|194294543 alpha 3 type IV collagen binding protein isoform 3 ... 67 8e-11
gi|5031717 alpha 3 type IV collagen binding protein isoform 1 [H... 67 8e-11
>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
Length = 747
Score = 1520 bits (3936), Expect = 0.0
Identities = 747/747 (100%), Positives = 747/747 (100%)
Query: 1 MQGGEPVSTMKVSESEGKLEGQATAVTPNKNSSCGGGISSSSSSRGGSAKGWQYSDHMEN 60
MQGGEPVSTMKVSESEGKLEGQATAVTPNKNSSCGGGISSSSSSRGGSAKGWQYSDHMEN
Sbjct: 1 MQGGEPVSTMKVSESEGKLEGQATAVTPNKNSSCGGGISSSSSSRGGSAKGWQYSDHMEN 60
Query: 61 VYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDS 120
VYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDS
Sbjct: 61 VYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDS 120
Query: 121 HTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSN 180
HTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSN
Sbjct: 121 HTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSN 180
Query: 181 SPISQRRPSQNAISFFNVGHSKLQSLSKRTNLPPDHLVEVREMMSHAEGQQRDLIRRIEC 240
SPISQRRPSQNAISFFNVGHSKLQSLSKRTNLPPDHLVEVREMMSHAEGQQRDLIRRIEC
Sbjct: 181 SPISQRRPSQNAISFFNVGHSKLQSLSKRTNLPPDHLVEVREMMSHAEGQQRDLIRRIEC 240
Query: 241 LPTSGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKI 300
LPTSGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKI
Sbjct: 241 LPTSGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKI 300
Query: 301 SLSNHYKNGADQPFATDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDL 360
SLSNHYKNGADQPFATDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDL
Sbjct: 301 SLSNHYKNGADQPFATDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDL 360
Query: 361 GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGAT 420
GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGAT
Sbjct: 361 GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGAT 420
Query: 421 AEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQG 480
AEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQG
Sbjct: 421 AEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQG 480
Query: 481 VTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFL 540
VTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFL
Sbjct: 481 VTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFL 540
Query: 541 GMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASI 600
GMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASI
Sbjct: 541 GMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASI 600
Query: 601 TFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLAVTK 660
TFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLAVTK
Sbjct: 601 TFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLAVTK 660
Query: 661 KRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKT 720
KRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKT
Sbjct: 661 KRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKT 720
Query: 721 KYFIKEGDGWVYHKPLWKIIPTTQPAE 747
KYFIKEGDGWVYHKPLWKIIPTTQPAE
Sbjct: 721 KYFIKEGDGWVYHKPLWKIIPTTQPAE 747
>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
sapiens]
Length = 764
Score = 788 bits (2034), Expect = 0.0
Identities = 406/718 (56%), Positives = 501/718 (69%), Gaps = 20/718 (2%)
Query: 35 GGGISSSSSSRGGSAKGWQYSDHMENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVN 94
GGG SS S S G + G L KYTNL+ GWQ R+FVL+ EAG+L+YFVN
Sbjct: 51 GGGSRSSPGSVAASPSGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVN 110
Query: 95 EQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICT 154
EQS++QKPRG L L+GA++S SDE H V +A+GE +KLRA DAKE+Q WV++L+ C
Sbjct: 111 EQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKEKQFWVTQLRACA 170
Query: 155 QHHTEAIGKNNPPLKSRSFSL----ASSSNSPISQRRPSQNAISFFNVGHSKLQSLSKRT 210
++H E K+ P +SRS +L +S SP SQR S A + H K + ++R
Sbjct: 171 KYHMEMNSKSAPSSRSRSLTLLPHGTPNSASPCSQRHLSVGAPGVVTITHHKSPAAARRA 230
Query: 211 NLP-PDHLVEVREMMSHAEGQQRDLIRRIECLPTSGHLSSLDQDLLMLKATSMATMNCLN 269
L EVREMM+ EGQQ++L+ IE LP SG L++LDQDLL+LKATS AT++CL
Sbjct: 231 KSQYSGQLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLG 290
Query: 270 DCFHILQLQ-HASHQKGSLP--SGTTIEWLEPKISLSNHYKNGA--DQPFATDQSKPVAV 324
+C ++LQ H + Q P S + W K + KNG P A+ +
Sbjct: 291 ECLNLLQQSVHQAGQPSQKPGASENILGWHGSKSHSTEQLKNGTLGSLPSASANITWAIL 350
Query: 325 PEEQPVAESGLLAREP----EEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLSQLKLG 380
P ++ EP E + ++DE D D +E +LG +E+QRS+ILHL+SQLKLG
Sbjct: 351 PNSAEDEQTSQPEPEPNSGSELVLSEDEKSDNEDKEETELGVMEDQRSIILHLISQLKLG 410
Query: 381 MDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGR 440
MDLT+VVLPTFILEKRSLLEMYADFM+HPDL +AIT GAT E+R+I FVEYYLT+FHEGR
Sbjct: 411 MDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYLTAFHEGR 470
Query: 441 KGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCY 500
KGA+AKKPYNPIIGETFHCSW++PK V +S S H P++ + S Y
Sbjct: 471 KGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEH-PMADDP-----SKSY 524
Query: 501 TVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHG 560
+RFVAEQVSHHPP+S FY EC E+++CVN HVWTKSKF+GMS+GV+M+GEG+L LLEHG
Sbjct: 525 KLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEHG 584
Query: 561 EEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVK 620
EEY F+LP AYARSILT+PWVELGGKVS+NCAKTGYSA++ FHTKPFYGGK+HRVTAEVK
Sbjct: 585 EEYVFTLPSAYARSILTIPWVELGGKVSINCAKTGYSATVIFHTKPFYGGKVHRVTAEVK 644
Query: 621 HNITNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKN 680
HN TNT+VC+ GEWN LEFTY+NGETK +D T L V K++RPLEKQ P ESR LW+
Sbjct: 645 HNPTNTIVCKAHGEWNGTLEFTYNNGETKVIDTTTLPVYPKKIRPLEKQGPMESRNLWRE 704
Query: 681 VTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWK 738
VT LR +ID ATE K LEE+QR EER R TPWK KYFI+EGDGWVY PLWK
Sbjct: 705 VTRYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYFIQEGDGWVYFNPLWK 762
>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
sapiens]
Length = 736
Score = 437 bits (1123), Expect = e-122
Identities = 214/398 (53%), Positives = 285/398 (71%), Gaps = 20/398 (5%)
Query: 345 ADDEIEDTCDHKEDDL--GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMY 402
+D ++ D+ D ++DD G+VEE +SVI+HLLSQ++LGMDLT+VVLPTFILE+RSLLEMY
Sbjct: 348 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 407
Query: 403 ADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWK 462
ADF +HPDLF++I++ +DRM++ V++YL++FH GRKG++AKKPYNPI+GE F C W
Sbjct: 408 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 467
Query: 463 MPK-SEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAE 521
+P +E + + S V+ ++ V FVAEQVSHHPP+S FYAE
Sbjct: 468 LPNDTEENTELVSEGPVPWVSKNS----------------VTFVAEQVSHHPPISAFYAE 511
Query: 522 CTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWV 581
C +K+ NAH+WTKSKFLGMSIGV +G+G +S L++ E Y + P Y RSILTVPWV
Sbjct: 512 CFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWV 571
Query: 582 ELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEF 641
ELGG+ ++NC+KTGYSA+I FHTKPFYGGK HR+TAE+ C ++GEWN V+
Sbjct: 572 ELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYA 631
Query: 642 TYSNGE-TKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTL 700
Y+ GE T +VD KL + KK+VR LE Q+ +ESR LWK+VT +L+ +ID ATE KH L
Sbjct: 632 KYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRL 691
Query: 701 EERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWK 738
EERQR E R R E W+T+ F ++G+ WVY +PL K
Sbjct: 692 EERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 729
Score = 77.0 bits (188), Expect = 6e-14
Identities = 40/97 (41%), Positives = 58/97 (59%), Gaps = 2/97 (2%)
Query: 63 GYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVN-EQSRNQKPRGTLQLAGAVISPSDEDSH 121
G L K+TN++ GWQYR+FVL+ AGLL Y+ + ++ RG ++L GAVI DED
Sbjct: 7 GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
Query: 122 TFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHT 158
TFT+ + + +A DA ER+ W+ L+ HT
Sbjct: 67 TFTI-TVDQKTFHFQARDADEREKWIHALEETILRHT 102
>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
sapiens]
Length = 746
Score = 437 bits (1123), Expect = e-122
Identities = 214/398 (53%), Positives = 285/398 (71%), Gaps = 20/398 (5%)
Query: 345 ADDEIEDTCDHKEDDL--GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMY 402
+D ++ D+ D ++DD G+VEE +SVI+HLLSQ++LGMDLT+VVLPTFILE+RSLLEMY
Sbjct: 358 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 417
Query: 403 ADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWK 462
ADF +HPDLF++I++ +DRM++ V++YL++FH GRKG++AKKPYNPI+GE F C W
Sbjct: 418 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 477
Query: 463 MPK-SEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAE 521
+P +E + + S V+ ++ V FVAEQVSHHPP+S FYAE
Sbjct: 478 LPNDTEENTELVSEGPVPWVSKNS----------------VTFVAEQVSHHPPISAFYAE 521
Query: 522 CTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWV 581
C +K+ NAH+WTKSKFLGMSIGV +G+G +S L++ E Y + P Y RSILTVPWV
Sbjct: 522 CFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWV 581
Query: 582 ELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEF 641
ELGG+ ++NC+KTGYSA+I FHTKPFYGGK HR+TAE+ C ++GEWN V+
Sbjct: 582 ELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYA 641
Query: 642 TYSNGE-TKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTL 700
Y+ GE T +VD KL + KK+VR LE Q+ +ESR LWK+VT +L+ +ID ATE KH L
Sbjct: 642 KYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRL 701
Query: 701 EERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWK 738
EERQR E R R E W+T+ F ++G+ WVY +PL K
Sbjct: 702 EERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 739
Score = 77.0 bits (188), Expect = 6e-14
Identities = 40/97 (41%), Positives = 58/97 (59%), Gaps = 2/97 (2%)
Query: 63 GYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVN-EQSRNQKPRGTLQLAGAVISPSDEDSH 121
G L K+TN++ GWQYR+FVL+ AGLL Y+ + ++ RG ++L GAVI DED
Sbjct: 7 GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
Query: 122 TFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHT 158
TFT+ + + +A DA ER+ W+ L+ HT
Sbjct: 67 TFTI-TVDQKTFHFQARDADEREKWIHALEETILRHT 102
>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
sapiens]
Length = 723
Score = 437 bits (1123), Expect = e-122
Identities = 214/398 (53%), Positives = 285/398 (71%), Gaps = 20/398 (5%)
Query: 345 ADDEIEDTCDHKEDDL--GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMY 402
+D ++ D+ D ++DD G+VEE +SVI+HLLSQ++LGMDLT+VVLPTFILE+RSLLEMY
Sbjct: 335 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 394
Query: 403 ADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWK 462
ADF +HPDLF++I++ +DRM++ V++YL++FH GRKG++AKKPYNPI+GE F C W
Sbjct: 395 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 454
Query: 463 MPK-SEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAE 521
+P +E + + S V+ ++ V FVAEQVSHHPP+S FYAE
Sbjct: 455 LPNDTEENTELVSEGPVPWVSKNS----------------VTFVAEQVSHHPPISAFYAE 498
Query: 522 CTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWV 581
C +K+ NAH+WTKSKFLGMSIGV +G+G +S L++ E Y + P Y RSILTVPWV
Sbjct: 499 CFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWV 558
Query: 582 ELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEF 641
ELGG+ ++NC+KTGYSA+I FHTKPFYGGK HR+TAE+ C ++GEWN V+
Sbjct: 559 ELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYA 618
Query: 642 TYSNGE-TKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTL 700
Y+ GE T +VD KL + KK+VR LE Q+ +ESR LWK+VT +L+ +ID ATE KH L
Sbjct: 619 KYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRL 678
Query: 701 EERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWK 738
EERQR E R R E W+T+ F ++G+ WVY +PL K
Sbjct: 679 EERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 716
Score = 77.0 bits (188), Expect = 6e-14
Identities = 40/97 (41%), Positives = 58/97 (59%), Gaps = 2/97 (2%)
Query: 63 GYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVN-EQSRNQKPRGTLQLAGAVISPSDEDSH 121
G L K+TN++ GWQYR+FVL+ AGLL Y+ + ++ RG ++L GAVI DED
Sbjct: 7 GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
Query: 122 TFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHT 158
TFT+ + + +A DA ER+ W+ L+ HT
Sbjct: 67 TFTI-TVDQKTFHFQARDADEREKWIHALEETILRHT 102
>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
sapiens]
Length = 626
Score = 437 bits (1123), Expect = e-122
Identities = 214/398 (53%), Positives = 285/398 (71%), Gaps = 20/398 (5%)
Query: 345 ADDEIEDTCDHKEDDL--GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMY 402
+D ++ D+ D ++DD G+VEE +SVI+HLLSQ++LGMDLT+VVLPTFILE+RSLLEMY
Sbjct: 238 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 297
Query: 403 ADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWK 462
ADF +HPDLF++I++ +DRM++ V++YL++FH GRKG++AKKPYNPI+GE F C W
Sbjct: 298 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 357
Query: 463 MPK-SEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAE 521
+P +E + + S V+ ++ V FVAEQVSHHPP+S FYAE
Sbjct: 358 LPNDTEENTELVSEGPVPWVSKNS----------------VTFVAEQVSHHPPISAFYAE 401
Query: 522 CTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWV 581
C +K+ NAH+WTKSKFLGMSIGV +G+G +S L++ E Y + P Y RSILTVPWV
Sbjct: 402 CFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWV 461
Query: 582 ELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEF 641
ELGG+ ++NC+KTGYSA+I FHTKPFYGGK HR+TAE+ C ++GEWN V+
Sbjct: 462 ELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYA 521
Query: 642 TYSNGE-TKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTL 700
Y+ GE T +VD KL + KK+VR LE Q+ +ESR LWK+VT +L+ +ID ATE KH L
Sbjct: 522 KYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRL 581
Query: 701 EERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWK 738
EERQR E R R E W+T+ F ++G+ WVY +PL K
Sbjct: 582 EERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 619
>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
sapiens]
Length = 571
Score = 437 bits (1123), Expect = e-122
Identities = 214/398 (53%), Positives = 285/398 (71%), Gaps = 20/398 (5%)
Query: 345 ADDEIEDTCDHKEDDL--GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMY 402
+D ++ D+ D ++DD G+VEE +SVI+HLLSQ++LGMDLT+VVLPTFILE+RSLLEMY
Sbjct: 183 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 242
Query: 403 ADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWK 462
ADF +HPDLF++I++ +DRM++ V++YL++FH GRKG++AKKPYNPI+GE F C W
Sbjct: 243 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 302
Query: 463 MPK-SEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAE 521
+P +E + + S V+ ++ V FVAEQVSHHPP+S FYAE
Sbjct: 303 LPNDTEENTELVSEGPVPWVSKNS----------------VTFVAEQVSHHPPISAFYAE 346
Query: 522 CTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWV 581
C +K+ NAH+WTKSKFLGMSIGV +G+G +S L++ E Y + P Y RSILTVPWV
Sbjct: 347 CFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWV 406
Query: 582 ELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEF 641
ELGG+ ++NC+KTGYSA+I FHTKPFYGGK HR+TAE+ C ++GEWN V+
Sbjct: 407 ELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYA 466
Query: 642 TYSNGE-TKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTL 700
Y+ GE T +VD KL + KK+VR LE Q+ +ESR LWK+VT +L+ +ID ATE KH L
Sbjct: 467 KYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRL 526
Query: 701 EERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWK 738
EERQR E R R E W+T+ F ++G+ WVY +PL K
Sbjct: 527 EERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 564
>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 437 bits (1123), Expect = e-122
Identities = 214/398 (53%), Positives = 285/398 (71%), Gaps = 20/398 (5%)
Query: 345 ADDEIEDTCDHKEDDL--GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMY 402
+D ++ D+ D ++DD G+VEE +SVI+HLLSQ++LGMDLT+VVLPTFILE+RSLLEMY
Sbjct: 170 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 229
Query: 403 ADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWK 462
ADF +HPDLF++I++ +DRM++ V++YL++FH GRKG++AKKPYNPI+GE F C W
Sbjct: 230 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 289
Query: 463 MPK-SEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAE 521
+P +E + + S V+ ++ V FVAEQVSHHPP+S FYAE
Sbjct: 290 LPNDTEENTELVSEGPVPWVSKNS----------------VTFVAEQVSHHPPISAFYAE 333
Query: 522 CTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWV 581
C +K+ NAH+WTKSKFLGMSIGV +G+G +S L++ E Y + P Y RSILTVPWV
Sbjct: 334 CFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWV 393
Query: 582 ELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEF 641
ELGG+ ++NC+KTGYSA+I FHTKPFYGGK HR+TAE+ C ++GEWN V+
Sbjct: 394 ELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYA 453
Query: 642 TYSNGE-TKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTL 700
Y+ GE T +VD KL + KK+VR LE Q+ +ESR LWK+VT +L+ +ID ATE KH L
Sbjct: 454 KYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRL 513
Query: 701 EERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWK 738
EERQR E R R E W+T+ F ++G+ WVY +PL K
Sbjct: 514 EERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 551
>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 437 bits (1123), Expect = e-122
Identities = 214/398 (53%), Positives = 285/398 (71%), Gaps = 20/398 (5%)
Query: 345 ADDEIEDTCDHKEDDL--GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMY 402
+D ++ D+ D ++DD G+VEE +SVI+HLLSQ++LGMDLT+VVLPTFILE+RSLLEMY
Sbjct: 170 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 229
Query: 403 ADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWK 462
ADF +HPDLF++I++ +DRM++ V++YL++FH GRKG++AKKPYNPI+GE F C W
Sbjct: 230 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 289
Query: 463 MPK-SEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAE 521
+P +E + + S V+ ++ V FVAEQVSHHPP+S FYAE
Sbjct: 290 LPNDTEENTELVSEGPVPWVSKNS----------------VTFVAEQVSHHPPISAFYAE 333
Query: 522 CTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWV 581
C +K+ NAH+WTKSKFLGMSIGV +G+G +S L++ E Y + P Y RSILTVPWV
Sbjct: 334 CFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWV 393
Query: 582 ELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEF 641
ELGG+ ++NC+KTGYSA+I FHTKPFYGGK HR+TAE+ C ++GEWN V+
Sbjct: 394 ELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYA 453
Query: 642 TYSNGE-TKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTL 700
Y+ GE T +VD KL + KK+VR LE Q+ +ESR LWK+VT +L+ +ID ATE KH L
Sbjct: 454 KYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRL 513
Query: 701 EERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWK 738
EERQR E R R E W+T+ F ++G+ WVY +PL K
Sbjct: 514 EERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 551
>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
[Homo sapiens]
Length = 879
Score = 218 bits (554), Expect = 2e-56
Identities = 137/414 (33%), Positives = 203/414 (49%), Gaps = 50/414 (12%)
Query: 316 TDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLS 375
+DQS+ P + + E E+ ++E EE +S++ LL
Sbjct: 327 SDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVS----------EENKSLMWTLLK 376
Query: 376 QLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTS 435
QL+ GMDL+RVVLPTF+LE RS L +D+ H DL A RM + +YL+
Sbjct: 377 QLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSG 436
Query: 436 FHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQV 495
F++ KG KKPYNPI+GETF C W P+++ S F
Sbjct: 437 FYKKPKGI--KKPYNPILGETFRCCWFHPQTD--SRTF---------------------- 470
Query: 496 GSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILS 555
++AEQVSHHPPVS F+ + C++ + KS+F G S+ + G+ L+
Sbjct: 471 --------YIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLT 522
Query: 556 LLEHGEEYTFSLPCAYARSIL-TVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHR 614
L E+YT ++P A+ + IL +ELGGKV++ CAK + A + F KPF+GG
Sbjct: 523 FLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSI 582
Query: 615 VTAEVKHNITNTVVCRVQGEWN-SVLEFTYSNGETKYVDLTKLAVTKKRVR----PLEKQ 669
K V+ + G W+ V +G + V ++R+R PLE+Q
Sbjct: 583 NQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQ 642
Query: 670 DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYF 723
ES RLW++VT ++ + + +AT+ K LEE QR R R E+ PWK + F
Sbjct: 643 TELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 696
>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 218 bits (554), Expect = 2e-56
Identities = 137/414 (33%), Positives = 203/414 (49%), Gaps = 50/414 (12%)
Query: 316 TDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLS 375
+DQS+ P + + E E+ ++E EE +S++ LL
Sbjct: 259 SDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVS----------EENKSLMWTLLK 308
Query: 376 QLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTS 435
QL+ GMDL+RVVLPTF+LE RS L +D+ H DL A RM + +YL+
Sbjct: 309 QLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSG 368
Query: 436 FHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQV 495
F++ KG KKPYNPI+GETF C W P+++ S F
Sbjct: 369 FYKKPKGI--KKPYNPILGETFRCCWFHPQTD--SRTF---------------------- 402
Query: 496 GSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILS 555
++AEQVSHHPPVS F+ + C++ + KS+F G S+ + G+ L+
Sbjct: 403 --------YIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLT 454
Query: 556 LLEHGEEYTFSLPCAYARSIL-TVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHR 614
L E+YT ++P A+ + IL +ELGGKV++ CAK + A + F KPF+GG
Sbjct: 455 FLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSI 514
Query: 615 VTAEVKHNITNTVVCRVQGEWN-SVLEFTYSNGETKYVDLTKLAVTKKRVR----PLEKQ 669
K V+ + G W+ V +G + V ++R+R PLE+Q
Sbjct: 515 NQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQ 574
Query: 670 DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYF 723
ES RLW++VT ++ + + +AT+ K LEE QR R R E+ PWK + F
Sbjct: 575 TELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628
>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 218 bits (554), Expect = 2e-56
Identities = 137/414 (33%), Positives = 203/414 (49%), Gaps = 50/414 (12%)
Query: 316 TDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLS 375
+DQS+ P + + E E+ ++E EE +S++ LL
Sbjct: 259 SDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVS----------EENKSLMWTLLK 308
Query: 376 QLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTS 435
QL+ GMDL+RVVLPTF+LE RS L +D+ H DL A RM + +YL+
Sbjct: 309 QLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSG 368
Query: 436 FHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQV 495
F++ KG KKPYNPI+GETF C W P+++ S F
Sbjct: 369 FYKKPKGI--KKPYNPILGETFRCCWFHPQTD--SRTF---------------------- 402
Query: 496 GSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILS 555
++AEQVSHHPPVS F+ + C++ + KS+F G S+ + G+ L+
Sbjct: 403 --------YIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLT 454
Query: 556 LLEHGEEYTFSLPCAYARSIL-TVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHR 614
L E+YT ++P A+ + IL +ELGGKV++ CAK + A + F KPF+GG
Sbjct: 455 FLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSI 514
Query: 615 VTAEVKHNITNTVVCRVQGEWN-SVLEFTYSNGETKYVDLTKLAVTKKRVR----PLEKQ 669
K V+ + G W+ V +G + V ++R+R PLE+Q
Sbjct: 515 NQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQ 574
Query: 670 DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYF 723
ES RLW++VT ++ + + +AT+ K LEE QR R R E+ PWK + F
Sbjct: 575 TELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628
>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
[Homo sapiens]
Length = 847
Score = 213 bits (541), Expect = 7e-55
Identities = 133/405 (32%), Positives = 204/405 (50%), Gaps = 53/405 (13%)
Query: 328 QPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVV 387
+P+ E+ + EE+ E T EE +S+I LL Q++ GMDL++VV
Sbjct: 330 EPLKETTYTEQSHEELGEAGEASQTET-------VSEENKSLIWTLLKQVRPGMDLSKVV 382
Query: 388 LPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKK 447
LPTFILE RS L+ +D+ H D R+ + V++YL+ F++ KG KK
Sbjct: 383 LPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGL--KK 440
Query: 448 PYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAE 507
PYNPI+GETF C W P++ S F ++AE
Sbjct: 441 PYNPILGETFRCLWIHPRTN--SKTF------------------------------YIAE 468
Query: 508 QVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSL 567
QVSHHPP+S FY + C++ + KSKF G S+ + GE L+ L GE+Y ++
Sbjct: 469 QVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTM 528
Query: 568 PCAYARSIL-TVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGK--LHRVTAEVKHNIT 624
P A+ + IL +ELGG V++ C KTGYSA + F KPF G +++++ ++K +
Sbjct: 529 PYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLK--LG 586
Query: 625 NTVVCRVQGEWNSVLEFTYSNGETKYV------DLTKLAVTKKRVRPLEKQDPFESRRLW 678
V+ ++G W+S + T + V D+ + + + V+ E+Q FES +LW
Sbjct: 587 KEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDIKQWRLIRHTVK-FEEQGDFESEKLW 645
Query: 679 KNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYF 723
+ VT ++ + +AT+ K+ LEE QR R R W K F
Sbjct: 646 QRVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTKNEEWSCKLF 690
>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
[Homo sapiens]
Length = 889
Score = 213 bits (541), Expect = 7e-55
Identities = 133/405 (32%), Positives = 204/405 (50%), Gaps = 53/405 (13%)
Query: 328 QPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVV 387
+P+ E+ + EE+ E T EE +S+I LL Q++ GMDL++VV
Sbjct: 372 EPLKETTYTEQSHEELGEAGEASQTET-------VSEENKSLIWTLLKQVRPGMDLSKVV 424
Query: 388 LPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKK 447
LPTFILE RS L+ +D+ H D R+ + V++YL+ F++ KG KK
Sbjct: 425 LPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGL--KK 482
Query: 448 PYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAE 507
PYNPI+GETF C W P++ S F ++AE
Sbjct: 483 PYNPILGETFRCLWIHPRTN--SKTF------------------------------YIAE 510
Query: 508 QVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSL 567
QVSHHPP+S FY + C++ + KSKF G S+ + GE L+ L GE+Y ++
Sbjct: 511 QVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTM 570
Query: 568 PCAYARSIL-TVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGK--LHRVTAEVKHNIT 624
P A+ + IL +ELGG V++ C KTGYSA + F KPF G +++++ ++K +
Sbjct: 571 PYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLK--LG 628
Query: 625 NTVVCRVQGEWNSVLEFTYSNGETKYV------DLTKLAVTKKRVRPLEKQDPFESRRLW 678
V+ ++G W+S + T + V D+ + + + V+ E+Q FES +LW
Sbjct: 629 KEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDIKQWRLIRHTVK-FEEQGDFESEKLW 687
Query: 679 KNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYF 723
+ VT ++ + +AT+ K+ LEE QR R R W K F
Sbjct: 688 QRVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTKNEEWSCKLF 732
>gi|4505531 oxysterol binding protein [Homo sapiens]
Length = 807
Score = 114 bits (285), Expect = 3e-25
Identities = 161/790 (20%), Positives = 302/790 (38%), Gaps = 157/790 (19%)
Query: 21 GQATAVTPNKNSSCGGGISSSSSSRGGSAKGWQYSDHMENVYGYLMKYTNLVTGWQYRFF 80
G A P GG S + G + +GW L K+TN + G+Q R+F
Sbjct: 63 GGVAAAGPAPAPPTGGSGGSGAGGSGSAREGW------------LFKWTNYIKGYQRRWF 110
Query: 81 VLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDA 140
VL+N GLL Y+ ++ RGT+ LA A I+ EDS F ++ + Y L+A+
Sbjct: 111 VLSN--GLLSYYRSKAEMRHTCRGTINLATANITV--EDSCNFIISNGGAQTYHLKASSE 166
Query: 141 KERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSNSPISQRRPSQNAISFFNVGH 200
ERQ WV+ L++ + + +++ S S + + R S
Sbjct: 167 VERQRWVTALELAKAKAVKMLAESDESGDEESVSQTDKTELQNTLRTLS----------- 215
Query: 201 SKLQSLSKRTNLPPDHLVEVREMMSHAEGQQRDLIRRIECLPTSGH--LSSLDQDLLMLK 258
SK++ LS +L H ++ +S E + LP + + +++ + +
Sbjct: 216 SKVEDLSTCNDLIAKHGTALQRSLSELESLK---------LPAESNEKIKQVNERATLFR 266
Query: 259 ATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKISLSNHYKNGADQPFATDQ 318
TS A +N D + Q QK LE + N ++ F
Sbjct: 267 ITSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERAFRGAT 326
Query: 319 SKPVAVP------EEQPVAESGLLAREPEE---------------------------INA 345
P P ++Q + G ++ E +E ++
Sbjct: 327 VLPANTPGNVGSGKDQCCSGKGDMSDEDDENEFFDAPEIITMPENLGHKRTGSNISGASS 386
Query: 346 DDEIEDTCDH-----KEDDLGAVEEQRSVILHLLSQLK--LGMDLTRVVLPTFILEKRSL 398
D +++ H K++ + + + L+L S +K +G +L+++ +P E S+
Sbjct: 387 DISLDEQYKHQLEETKKEKRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSM 446
Query: 399 LEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFH 458
L+ + + + +L + +++ + ++S+ KP+NP++GETF
Sbjct: 447 LQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSY--STTVFRTSKPFNPLLGETF- 503
Query: 459 CSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGF 518
L ++ + Y R + EQVSHHPP +
Sbjct: 504 --------------------------------ELDRLEENGY--RSLCEQVSHHPPAAAH 529
Query: 519 YAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTV 578
+AE ++ + + SKF G + + +G G YT+ +I+
Sbjct: 530 HAE-SKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKKVTTTVHNIIVG 588
Query: 579 P-WVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHR-VTAEVKHNITNTVVCRVQGEWN 636
W++ G++ + KTG ++ F ++ + R VT EV + + V + G W+
Sbjct: 589 KLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVT-DPSGKVHFALLGTWD 647
Query: 637 SVLE-------FTYSNGETKY----VDLTKLAVTKKRVRPLEKQDPFESRRL------WK 679
+E + G+ + + +++ + K+ P ++ + L W+
Sbjct: 648 EKMECFKVQPVIGENGGDARQRGHEAEESRVMLWKRNPLPKNAENMYYFSELALTLNAWE 707
Query: 680 N---VTDS--------LRESEIDKATEHKHTLEERQRTEERHR-------TETGT---PW 718
+ TDS + D+A K LEE+QR + R TE GT P+
Sbjct: 708 SGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAMKATEDGTPYDPY 767
Query: 719 KTKYFIKEGD 728
K +F ++ D
Sbjct: 768 KALWFERKKD 777
>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
sapiens]
Length = 437
Score = 110 bits (276), Expect = 4e-24
Identities = 96/422 (22%), Positives = 161/422 (38%), Gaps = 102/422 (24%)
Query: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
+GM+L+++ +P E S L+ ++M H L ++ + +RM + +++
Sbjct: 44 IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAV-- 101
Query: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
+ KP+NP++GET+ ++ D
Sbjct: 102 ASQWERTGKPFNPLLGETY------------------------------------ELVRD 125
Query: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
R ++EQVSHHPP+S F+AE + ++ K KF G S+ G L LLE
Sbjct: 126 DLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLE 185
Query: 559 HGEEYTFSLP-CAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTA 617
H E YT++ P C I+ W+E G V + KTG + F +G +LH+V
Sbjct: 186 HNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEG 245
Query: 618 EVKHNITNTVVCRVQGEWNSVLEF-------TYSNGETKYVDLTKLAVTKKRVRPLEKQD 670
++ + +C + G+W L Y + K + K + L++
Sbjct: 246 YIQDK-SKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMP 304
Query: 671 PFESRR---------LWK---------------------NVTDSLRES------------ 688
+S LW+ N D ES
Sbjct: 305 VPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPD 364
Query: 689 -------EIDKATEHKHTLEERQRTEERHRTETGTPWKTKYF------IKEGDGWVYHKP 735
EID+A+E K LEE+QR ++R+++ WKT++F W+Y
Sbjct: 365 IRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGS 424
Query: 736 LW 737
W
Sbjct: 425 YW 426
>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
sapiens]
Length = 950
Score = 110 bits (276), Expect = 4e-24
Identities = 96/422 (22%), Positives = 161/422 (38%), Gaps = 102/422 (24%)
Query: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
+GM+L+++ +P E S L+ ++M H L ++ + +RM + +++
Sbjct: 557 IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAV-- 614
Query: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
+ KP+NP++GET+ ++ D
Sbjct: 615 ASQWERTGKPFNPLLGETY------------------------------------ELVRD 638
Query: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
R ++EQVSHHPP+S F+AE + ++ K KF G S+ G L LLE
Sbjct: 639 DLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLE 698
Query: 559 HGEEYTFSLP-CAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTA 617
H E YT++ P C I+ W+E G V + KTG + F +G +LH+V
Sbjct: 699 HNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEG 758
Query: 618 EVKHNITNTVVCRVQGEWNSVLEF-------TYSNGETKYVDLTKLAVTKKRVRPLEKQD 670
++ + +C + G+W L Y + K + K + L++
Sbjct: 759 YIQDK-SKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMP 817
Query: 671 PFESRR---------LWK---------------------NVTDSLRES------------ 688
+S LW+ N D ES
Sbjct: 818 VPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPD 877
Query: 689 -------EIDKATEHKHTLEERQRTEERHRTETGTPWKTKYF------IKEGDGWVYHKP 735
EID+A+E K LEE+QR ++R+++ WKT++F W+Y
Sbjct: 878 IRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGS 937
Query: 736 LW 737
W
Sbjct: 938 YW 939
>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
Length = 916
Score = 102 bits (255), Expect = 1e-21
Identities = 158/767 (20%), Positives = 279/767 (36%), Gaps = 155/767 (20%)
Query: 58 MENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSD 117
+++ G+L+K+TN + G+Q R+FVL N GLL Y+ N+ RGT+ L+ A I D
Sbjct: 182 LDSFEGWLLKWTNYLKGYQRRWFVLGN--GLLSYYRNQGEMAHTCRGTINLSTAHIDTED 239
Query: 118 EDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLAS 177
T A S Y L+A+ +RQ W++ L++ + + +
Sbjct: 240 SCGILLTSGARS---YHLKASSEVDRQQWITALELAKAKAVRVMNTH-----------SD 285
Query: 178 SSNSPISQRRPSQNAISFFNVGHSKLQSLSKRTNLPPDHLVEVREMMS-HAEGQQRDL-- 234
S P+ S+L K +L D L ++++ H QR L
Sbjct: 286 DSGDDDEATTPADK---------SELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTE 336
Query: 235 IRRIECLPTSGH-LSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTI 293
+ ++ SG L +++ + + TS A +N D + ++ Q+
Sbjct: 337 LDGLKIPSESGEKLKVVNERATLFRITSNAMINACRDFLELAEIHSRKWQRALQYEQEQR 396
Query: 294 EWLEPKISLSNHYKNGADQPFATDQSKPV----AVPEEQPVAESGLLAREPEEINADDEI 349
LE I N ++ F + +P + E + G + E E+ D +
Sbjct: 397 VHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAM 456
Query: 350 EDT-------CDHKEDDLGA------------------------------------VEEQ 366
ED+ + KED A + +
Sbjct: 457 EDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNK 516
Query: 367 RSVILHLLSQLK--LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDR 424
+ L+L S +K +G +L+R+ +P E S+L+ + + + L + ++ ++
Sbjct: 517 PNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQ 576
Query: 425 MIRF----VEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQG 480
M V Y T+ H KP+NP++GETF
Sbjct: 577 MCLVAAFSVSSYSTTVHR------IAKPFNPMLGETFEL--------------------- 609
Query: 481 VTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFL 540
+ L +G +R + EQVSHHPP + Y ++ + + SKF
Sbjct: 610 ---------DRLDDMG-----LRSLCEQVSHHPPSAAHYV-FSKHGWSLWQEITISSKFR 654
Query: 541 GMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVP-WVELGGKVSVNCAKTGYSAS 599
G I + +G L G Y + + +I+ W++ G + + KT
Sbjct: 655 GKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQ 714
Query: 600 ITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFT----------YSNGETK 649
+ F ++ + R V + + G W+ +E + S+G+ K
Sbjct: 715 LKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQK 774
Query: 650 --YVDLTKLAVTKKRVRPLEKQDPFESRRLWKNV---------TDS--------LRESEI 690
Y L+ + KK P ++ + L + TDS + +
Sbjct: 775 TVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRW 834
Query: 691 DKATEHKHTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLW 737
D+A K LEE+QR R R E P + +E + Y PLW
Sbjct: 835 DEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAY-TPLW 880
>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
[Homo sapiens]
Length = 480
Score = 88.6 bits (218), Expect = 2e-17
Identities = 64/262 (24%), Positives = 111/262 (42%), Gaps = 40/262 (15%)
Query: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
+G++L+++ +P E S L+ ++M H L + +RM + +++
Sbjct: 84 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAV-- 141
Query: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
+ KP+NP++GET+ L E L
Sbjct: 142 ASQWERTGKPFNPLLGETYE----------------------------LIREDLG----- 168
Query: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
RF++EQVSHHPP+S F++E + ++ K KF G S+ G L LL+
Sbjct: 169 ---FRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLK 225
Query: 559 HGEEYTFSLP-CAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTA 617
H E YT++ P C I+ W+E G V + +TG+ + F +G +LH+V
Sbjct: 226 HNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEG 285
Query: 618 EVKHNITNTVVCRVQGEWNSVL 639
++ + + G+W L
Sbjct: 286 HIQDK-NKKKLFMIYGKWTECL 306
Score = 34.7 bits (78), Expect = 0.33
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 666 LEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYF 723
+EK P RL ++ + +D A++ K LEE+QR R R + W+T++F
Sbjct: 393 MEKTLPPTDCRLRPDIR-GMENGNMDLASQEKERLEEKQREARRERAKEEAEWQTRWF 449
>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
sapiens]
Length = 468
Score = 88.6 bits (218), Expect = 2e-17
Identities = 64/262 (24%), Positives = 111/262 (42%), Gaps = 40/262 (15%)
Query: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
+G++L+++ +P E S L+ ++M H L + +RM + +++
Sbjct: 72 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAV-- 129
Query: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
+ KP+NP++GET+ L E L
Sbjct: 130 ASQWERTGKPFNPLLGETYE----------------------------LIREDLG----- 156
Query: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
RF++EQVSHHPP+S F++E + ++ K KF G S+ G L LL+
Sbjct: 157 ---FRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLK 213
Query: 559 HGEEYTFSLP-CAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTA 617
H E YT++ P C I+ W+E G V + +TG+ + F +G +LH+V
Sbjct: 214 HNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEG 273
Query: 618 EVKHNITNTVVCRVQGEWNSVL 639
++ + + G+W L
Sbjct: 274 HIQDK-NKKKLFMIYGKWTECL 294
Score = 34.7 bits (78), Expect = 0.33
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 666 LEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYF 723
+EK P RL ++ + +D A++ K LEE+QR R R + W+T++F
Sbjct: 381 MEKTLPPTDCRLRPDIR-GMENGNMDLASQEKERLEEKQREARRERAKEEAEWQTRWF 437
>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
Length = 842
Score = 82.0 bits (201), Expect = 2e-15
Identities = 86/388 (22%), Positives = 155/388 (39%), Gaps = 74/388 (19%)
Query: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
+G DL++V +P + E + L+ + + + L + A +RM+ ++ + S +
Sbjct: 487 IGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERMV-YIAAFAVSAYS 545
Query: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
KP+NP++GET+ C P G
Sbjct: 546 STYHRAGCKPFNPVLGETYECE------------------------RPDRG--------- 572
Query: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
RF++EQVSHHPP+S +AE +E W K+KF G S+ + VG +SL
Sbjct: 573 ---FRFISEQVSHHPPISACHAE-SENFAFWQDMKW-KNKFWGKSLEIVPVGTVNVSLPR 627
Query: 559 HGEEYTFSLPCAYARSILT-VPWVELGGKVSV-NCAKTGYSASITFHTKPFYGGKLHRVT 616
G+ + ++ + ++L+ W+E G+V + N + ITF ++ +H V
Sbjct: 628 FGDHFEWNKVTSCIHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQ 687
Query: 617 AEVKHNITNTVVCRVQGEWNSVL-------------------EFTYSNGETKY-VDLTKL 656
V + V+ R+ G+W+ L + + G T++ ++L +L
Sbjct: 688 GAVLSR-SGRVLHRLFGKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNEL 746
Query: 657 AVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGT 716
KR P +R L E I A K +E+ QR + E
Sbjct: 747 TAELKRSLPSTDTRLRPDQRY-------LEEGNIQAAEAQKRRIEQLQRDRRKVMEENNI 799
Query: 717 PWKTKYFIKEGDG-----WVYHKPLWKI 739
+ ++F ++ D WV + W++
Sbjct: 800 VHQARFFRRQTDSSGKEWWVTNNTYWRL 827
>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
[Homo sapiens]
Length = 938
Score = 80.1 bits (196), Expect = 7e-15
Identities = 81/383 (21%), Positives = 151/383 (39%), Gaps = 64/383 (16%)
Query: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
+G DL++V +P + E + L+ + M + +L + +RM+ + ++ +
Sbjct: 583 IGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCS 642
Query: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
A KP+NP++GET+ C +
Sbjct: 643 TYFRA-GSKPFNPVLGETYECI------------------------------------RE 665
Query: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
RF +EQVSHHPP+S C + + K+KF G S+ + VG + L +
Sbjct: 666 DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPK 723
Query: 559 HGEEYTFSLPCAYARSILT-VPWVELGGKVSVNCAKTGYS-ASITFHTKPFYGGKLHRVT 616
+G+ Y ++ +IL+ W+E G+V++ K+ +TF ++ ++ V
Sbjct: 724 YGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQ 783
Query: 617 AEVKHNITNTVVCRVQGEWNSVL-------------EFTYSNGETKYVDLTKLAVTKKRV 663
V V R+ G+W+ L + Y T+ A+ +
Sbjct: 784 GVVIDQ-EGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNEL 842
Query: 664 RPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTK 721
P+ K P ++R ++ L E ++ A K +EE QR+ R+ E K
Sbjct: 843 DPVLKDLLPPTDAR--FRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPK 900
Query: 722 YFIK-----EGDGWVYHKPLWKI 739
+F K + + WV + W++
Sbjct: 901 FFKKVIDANQREAWVSNDTYWEL 923
>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
[Homo sapiens]
Length = 934
Score = 80.1 bits (196), Expect = 7e-15
Identities = 81/383 (21%), Positives = 151/383 (39%), Gaps = 64/383 (16%)
Query: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
+G DL++V +P + E + L+ + M + +L + +RM+ + ++ +
Sbjct: 579 IGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCS 638
Query: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
A KP+NP++GET+ C +
Sbjct: 639 TYFRA-GSKPFNPVLGETYECI------------------------------------RE 661
Query: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
RF +EQVSHHPP+S C + + K+KF G S+ + VG + L +
Sbjct: 662 DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPK 719
Query: 559 HGEEYTFSLPCAYARSILT-VPWVELGGKVSVNCAKTGYS-ASITFHTKPFYGGKLHRVT 616
+G+ Y ++ +IL+ W+E G+V++ K+ +TF ++ ++ V
Sbjct: 720 YGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQ 779
Query: 617 AEVKHNITNTVVCRVQGEWNSVL-------------EFTYSNGETKYVDLTKLAVTKKRV 663
V V R+ G+W+ L + Y T+ A+ +
Sbjct: 780 GVVIDQ-EGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNEL 838
Query: 664 RPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTK 721
P+ K P ++R ++ L E ++ A K +EE QR+ R+ E K
Sbjct: 839 DPVLKDLLPPTDAR--FRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPK 896
Query: 722 YFIK-----EGDGWVYHKPLWKI 739
+F K + + WV + W++
Sbjct: 897 FFKKVIDANQREAWVSNDTYWEL 919
>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
[Homo sapiens]
Length = 820
Score = 75.5 bits (184), Expect = 2e-13
Identities = 76/371 (20%), Positives = 148/371 (39%), Gaps = 60/371 (16%)
Query: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
+G DL++V +P + E + L+ + + + +L + +RM+ + ++++
Sbjct: 469 IGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYAS 528
Query: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
A KP+NP++GET+ C +
Sbjct: 529 SYYRA-GSKPFNPVLGETYECI------------------------------------RE 551
Query: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
+F +EQVSHHPP+S +AE R V K+KF G S+ + +G ++L
Sbjct: 552 DKGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 609
Query: 559 HGEEYTFSLPCAYARSILT-VPWVELGGKVSV-NCAKTGYSASITFHTKPFYGGKLHRVT 616
G+ + ++ + +IL+ W+E G++ + N + F ++ H +
Sbjct: 610 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 669
Query: 617 AEVKHNITNTVVCRVQGEWNSVL-------------EFTYSNGETKYVDLTKLAVTKKRV 663
V + + V R+ G+W+ + G +Y T+ A+ +
Sbjct: 670 GTV-FDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEM 728
Query: 664 RPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTK 721
P K P ++R ++ L E +++A K +E+ QR R E + +
Sbjct: 729 DPSSKSLLPPTDTR--FRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPR 786
Query: 722 YFIK-EGDGWV 731
+F K + D WV
Sbjct: 787 FFRKSDDDSWV 797
>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
[Homo sapiens]
Length = 851
Score = 75.5 bits (184), Expect = 2e-13
Identities = 76/371 (20%), Positives = 148/371 (39%), Gaps = 60/371 (16%)
Query: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
+G DL++V +P + E + L+ + + + +L + +RM+ + ++++
Sbjct: 500 IGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYAS 559
Query: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
A KP+NP++GET+ C +
Sbjct: 560 SYYRA-GSKPFNPVLGETYECI------------------------------------RE 582
Query: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
+F +EQVSHHPP+S +AE R V K+KF G S+ + +G ++L
Sbjct: 583 DKGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 640
Query: 559 HGEEYTFSLPCAYARSILT-VPWVELGGKVSV-NCAKTGYSASITFHTKPFYGGKLHRVT 616
G+ + ++ + +IL+ W+E G++ + N + F ++ H +
Sbjct: 641 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 700
Query: 617 AEVKHNITNTVVCRVQGEWNSVL-------------EFTYSNGETKYVDLTKLAVTKKRV 663
V + + V R+ G+W+ + G +Y T+ A+ +
Sbjct: 701 GTV-FDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEM 759
Query: 664 RPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTK 721
P K P ++R ++ L E +++A K +E+ QR R E + +
Sbjct: 760 DPSSKSLLPPTDTR--FRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPR 817
Query: 722 YFIK-EGDGWV 731
+F K + D WV
Sbjct: 818 FFRKSDDDSWV 828
>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
[Homo sapiens]
Length = 856
Score = 75.5 bits (184), Expect = 2e-13
Identities = 76/371 (20%), Positives = 148/371 (39%), Gaps = 60/371 (16%)
Query: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
+G DL++V +P + E + L+ + + + +L + +RM+ + ++++
Sbjct: 505 IGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYAS 564
Query: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
A KP+NP++GET+ C +
Sbjct: 565 SYYRA-GSKPFNPVLGETYECI------------------------------------RE 587
Query: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
+F +EQVSHHPP+S +AE R V K+KF G S+ + +G ++L
Sbjct: 588 DKGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 645
Query: 559 HGEEYTFSLPCAYARSILT-VPWVELGGKVSV-NCAKTGYSASITFHTKPFYGGKLHRVT 616
G+ + ++ + +IL+ W+E G++ + N + F ++ H +
Sbjct: 646 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 705
Query: 617 AEVKHNITNTVVCRVQGEWNSVL-------------EFTYSNGETKYVDLTKLAVTKKRV 663
V + + V R+ G+W+ + G +Y T+ A+ +
Sbjct: 706 GTV-FDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEM 764
Query: 664 RPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTK 721
P K P ++R ++ L E +++A K +E+ QR R E + +
Sbjct: 765 DPSSKSLLPPTDTR--FRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPR 822
Query: 722 YFIK-EGDGWV 731
+F K + D WV
Sbjct: 823 FFRKSDDDSWV 833
>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
[Homo sapiens]
Length = 887
Score = 75.5 bits (184), Expect = 2e-13
Identities = 76/371 (20%), Positives = 148/371 (39%), Gaps = 60/371 (16%)
Query: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
+G DL++V +P + E + L+ + + + +L + +RM+ + ++++
Sbjct: 536 IGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYAS 595
Query: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
A KP+NP++GET+ C +
Sbjct: 596 SYYRA-GSKPFNPVLGETYECI------------------------------------RE 618
Query: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
+F +EQVSHHPP+S +AE R V K+KF G S+ + +G ++L
Sbjct: 619 DKGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 676
Query: 559 HGEEYTFSLPCAYARSILT-VPWVELGGKVSV-NCAKTGYSASITFHTKPFYGGKLHRVT 616
G+ + ++ + +IL+ W+E G++ + N + F ++ H +
Sbjct: 677 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 736
Query: 617 AEVKHNITNTVVCRVQGEWNSVL-------------EFTYSNGETKYVDLTKLAVTKKRV 663
V + + V R+ G+W+ + G +Y T+ A+ +
Sbjct: 737 GTV-FDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEM 795
Query: 664 RPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTK 721
P K P ++R ++ L E +++A K +E+ QR R E + +
Sbjct: 796 DPSSKSLLPPTDTR--FRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPR 853
Query: 722 YFIK-EGDGWV 731
+F K + D WV
Sbjct: 854 FFRKSDDDSWV 864
>gi|14165452 alpha 3 type IV collagen binding protein isoform 2
[Homo sapiens]
Length = 598
Score = 66.6 bits (161), Expect = 8e-11
Identities = 49/146 (33%), Positives = 71/146 (48%), Gaps = 10/146 (6%)
Query: 63 GYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHT 122
G L K+TN + GWQ R+ VL N A L Y+ +E RG++ L+ AVI+P D D
Sbjct: 28 GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCRGSICLSKAVITPHDFDECR 85
Query: 123 FTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSNSP 182
F ++ Y LRA D RQ W+ ++ QH TE+ G + R S+ S +
Sbjct: 86 FDISVNDSVWY-LRAQDPDHRQQWIDAIE---QHKTES-GYGSESSLRRHGSMVSLVSGA 140
Query: 183 ISQRRPSQNAISFFNVGHSKLQSLSK 208
S + S F GHS + L++
Sbjct: 141 SGY---SATSTSSFKKGHSLREKLAE 163
>gi|194294543 alpha 3 type IV collagen binding protein isoform 3
[Homo sapiens]
Length = 752
Score = 66.6 bits (161), Expect = 8e-11
Identities = 49/146 (33%), Positives = 71/146 (48%), Gaps = 10/146 (6%)
Query: 63 GYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHT 122
G L K+TN + GWQ R+ VL N A L Y+ +E RG++ L+ AVI+P D D
Sbjct: 156 GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCRGSICLSKAVITPHDFDECR 213
Query: 123 FTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSNSP 182
F ++ Y LRA D RQ W+ ++ QH TE+ G + R S+ S +
Sbjct: 214 FDISVNDSVWY-LRAQDPDHRQQWIDAIE---QHKTES-GYGSESSLRRHGSMVSLVSGA 268
Query: 183 ISQRRPSQNAISFFNVGHSKLQSLSK 208
S + S F GHS + L++
Sbjct: 269 SGY---SATSTSSFKKGHSLREKLAE 291
>gi|5031717 alpha 3 type IV collagen binding protein isoform 1 [Homo
sapiens]
Length = 624
Score = 66.6 bits (161), Expect = 8e-11
Identities = 49/146 (33%), Positives = 71/146 (48%), Gaps = 10/146 (6%)
Query: 63 GYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHT 122
G L K+TN + GWQ R+ VL N A L Y+ +E RG++ L+ AVI+P D D
Sbjct: 28 GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCRGSICLSKAVITPHDFDECR 85
Query: 123 FTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSNSP 182
F ++ Y LRA D RQ W+ ++ QH TE+ G + R S+ S +
Sbjct: 86 FDISVNDSVWY-LRAQDPDHRQQWIDAIE---QHKTES-GYGSESSLRRHGSMVSLVSGA 140
Query: 183 ISQRRPSQNAISFFNVGHSKLQSLSK 208
S + S F GHS + L++
Sbjct: 141 SGY---SATSTSSFKKGHSLREKLAE 163
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,984,528
Number of Sequences: 37866
Number of extensions: 1294231
Number of successful extensions: 5249
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 5083
Number of HSP's gapped (non-prelim): 140
length of query: 747
length of database: 18,247,518
effective HSP length: 110
effective length of query: 637
effective length of database: 14,082,258
effective search space: 8970398346
effective search space used: 8970398346
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.