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Search of human proteins with 19923084
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923084 polycystin-1L1 [Homo sapiens]
(2849 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923084 polycystin-1L1 [Homo sapiens] 5785 0.0
gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens] 219 4e-56
gi|5174633 receptor for egg jelly-like protein precursor [Homo s... 151 1e-35
gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens] 122 7e-27
gi|31559825 polycystin 1-like 3 [Homo sapiens] 122 7e-27
gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 121 9e-27
gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 121 9e-27
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens] 121 1e-26
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens] 121 1e-26
gi|4505835 polycystin 2 [Homo sapiens] 99 8e-20
gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap... 79 5e-14
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 79 5e-14
gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sap... 79 5e-14
gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens] 78 1e-13
gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens] 74 3e-12
gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens] 62 1e-08
gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo ... 62 1e-08
gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo ... 62 1e-08
gi|44889475 RAB6 interacting protein 1 [Homo sapiens] 47 3e-04
gi|122891862 DENN/MADD domain containing 5B [Homo sapiens] 45 0.001
gi|66529203 hypothetical protein LOC57714 [Homo sapiens] 44 0.002
gi|187960059 syndecan 3 [Homo sapiens] 42 0.009
gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens] 41 0.019
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 40 0.043
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 40 0.043
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 40 0.043
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 40 0.043
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 40 0.043
gi|163965366 nascent polypeptide-associated complex alpha subuni... 40 0.043
gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens] 39 0.056
>gi|19923084 polycystin-1L1 [Homo sapiens]
Length = 2849
Score = 5785 bits (15008), Expect = 0.0
Identities = 2849/2849 (100%), Positives = 2849/2849 (100%)
Query: 1 MAEEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCSPPGGGLWVEVYANHV 60
MAEEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCSPPGGGLWVEVYANHV
Sbjct: 1 MAEEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCSPPGGGLWVEVYANHV 60
Query: 61 LLMSDGKCGCPWCALNGKAEDRESQSPSSSASRQKNIWKTTSEAALSVVNEKTQAVVNEK 120
LLMSDGKCGCPWCALNGKAEDRESQSPSSSASRQKNIWKTTSEAALSVVNEKTQAVVNEK
Sbjct: 61 LLMSDGKCGCPWCALNGKAEDRESQSPSSSASRQKNIWKTTSEAALSVVNEKTQAVVNEK 120
Query: 121 TQAPLDCDNSADRIPHKPFIIIARAWSSGGPRFHHRRLCATGTADSTFSALLQLQGTTSA 180
TQAPLDCDNSADRIPHKPFIIIARAWSSGGPRFHHRRLCATGTADSTFSALLQLQGTTSA
Sbjct: 121 TQAPLDCDNSADRIPHKPFIIIARAWSSGGPRFHHRRLCATGTADSTFSALLQLQGTTSA 180
Query: 181 AAPCSLKMEASCCVLRLLCCAEDVATGLLPGTVTMETPTKVARPTQTSSQRVPLWPISHF 240
AAPCSLKMEASCCVLRLLCCAEDVATGLLPGTVTMETPTKVARPTQTSSQRVPLWPISHF
Sbjct: 181 AAPCSLKMEASCCVLRLLCCAEDVATGLLPGTVTMETPTKVARPTQTSSQRVPLWPISHF 240
Query: 241 PTSPRSSHGLPPGIPRTPSFTASQSGSEILYPPTQHPPVAILARNSDNFMNPVLNCSLEV 300
PTSPRSSHGLPPGIPRTPSFTASQSGSEILYPPTQHPPVAILARNSDNFMNPVLNCSLEV
Sbjct: 241 PTSPRSSHGLPPGIPRTPSFTASQSGSEILYPPTQHPPVAILARNSDNFMNPVLNCSLEV 300
Query: 301 EARAPPNLGFRVHMASGEALCLMMDFGDSSGVEMRLHNMSEAMAVTAYHQYSKGIFFHLL 360
EARAPPNLGFRVHMASGEALCLMMDFGDSSGVEMRLHNMSEAMAVTAYHQYSKGIFFHLL
Sbjct: 301 EARAPPNLGFRVHMASGEALCLMMDFGDSSGVEMRLHNMSEAMAVTAYHQYSKGIFFHLL 360
Query: 361 HFQLDMSTYKEAETQNTTLNVYLCQSENSCLEDSDPSNLGYELISAFVTKGVYMLKAVIY 420
HFQLDMSTYKEAETQNTTLNVYLCQSENSCLEDSDPSNLGYELISAFVTKGVYMLKAVIY
Sbjct: 361 HFQLDMSTYKEAETQNTTLNVYLCQSENSCLEDSDPSNLGYELISAFVTKGVYMLKAVIY 420
Query: 421 NEFHGTEVELGPYYVEIGHEAVSAFMNSSSVHEDEVLVFADSQVNQKSTVVIHHFPSIPS 480
NEFHGTEVELGPYYVEIGHEAVSAFMNSSSVHEDEVLVFADSQVNQKSTVVIHHFPSIPS
Sbjct: 421 NEFHGTEVELGPYYVEIGHEAVSAFMNSSSVHEDEVLVFADSQVNQKSTVVIHHFPSIPS 480
Query: 481 YNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTVFATDTDITFTAVTKETIPLEFEW 540
YNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTVFATDTDITFTAVTKETIPLEFEW
Sbjct: 481 YNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTVFATDTDITFTAVTKETIPLEFEW 540
Query: 541 YFGEDPPVRTTSRSIKKRLSIPQWYRVMVKASNRMSSVVSEPHVIRVQKKIVANRLTSPS 600
YFGEDPPVRTTSRSIKKRLSIPQWYRVMVKASNRMSSVVSEPHVIRVQKKIVANRLTSPS
Sbjct: 541 YFGEDPPVRTTSRSIKKRLSIPQWYRVMVKASNRMSSVVSEPHVIRVQKKIVANRLTSPS 600
Query: 601 SALVNASVAFECWINFGTDVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSA 660
SALVNASVAFECWINFGTDVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSA
Sbjct: 601 SALVNASVAFECWINFGTDVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSA 660
Query: 661 STLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEAAVFCDISQGLSYTWNLM 720
STLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEAAVFCDISQGLSYTWNLM
Sbjct: 661 STLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEAAVFCDISQGLSYTWNLM 720
Query: 721 DSEGLPVSLPAAVDTHRQTLILPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAP 780
DSEGLPVSLPAAVDTHRQTLILPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAP
Sbjct: 721 DSEGLPVSLPAAVDTHRQTLILPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAP 780
Query: 781 VSVISEGTHLFFSRTTSSPIVLRGTQSFDPDDPGATLRYHWECATAGSPAHPCFDSSTAH 840
VSVISEGTHLFFSRTTSSPIVLRGTQSFDPDDPGATLRYHWECATAGSPAHPCFDSSTAH
Sbjct: 781 VSVISEGTHLFFSRTTSSPIVLRGTQSFDPDDPGATLRYHWECATAGSPAHPCFDSSTAH 840
Query: 841 QLDAAAPTVSFEAQWLSDSYDQFLVMLRVSSGGRNSSETRVFLSPYPDSAFRFVHISWVS 900
QLDAAAPTVSFEAQWLSDSYDQFLVMLRVSSGGRNSSETRVFLSPYPDSAFRFVHISWVS
Sbjct: 841 QLDAAAPTVSFEAQWLSDSYDQFLVMLRVSSGGRNSSETRVFLSPYPDSAFRFVHISWVS 900
Query: 901 FKDTFVNWNDELSLQAMCEDCSEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL 960
FKDTFVNWNDELSLQAMCEDCSEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL
Sbjct: 901 FKDTFVNWNDELSLQAMCEDCSEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL 960
Query: 961 GAISESSQLNLLPTEPGTADPDATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIP 1020
GAISESSQLNLLPTEPGTADPDATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIP
Sbjct: 961 GAISESSQLNLLPTEPGTADPDATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIP 1020
Query: 1021 PAGDSAVLGEAPEEGSLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDIQEA 1080
PAGDSAVLGEAPEEGSLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDIQEA
Sbjct: 1021 PAGDSAVLGEAPEEGSLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDIQEA 1080
Query: 1081 IPSGGRQPAKDTSFPGSGPSLSAEESPGDGDNLVDPSLSAGRAEPVLMIDWPKALLGRAV 1140
IPSGGRQPAKDTSFPGSGPSLSAEESPGDGDNLVDPSLSAGRAEPVLMIDWPKALLGRAV
Sbjct: 1081 IPSGGRQPAKDTSFPGSGPSLSAEESPGDGDNLVDPSLSAGRAEPVLMIDWPKALLGRAV 1140
Query: 1141 FQGYSSSGITEQTVTIKPYSLSSGETYVLQVSVASKHGLLGKAQLYLTVNPAPRDMACQV 1200
FQGYSSSGITEQTVTIKPYSLSSGETYVLQVSVASKHGLLGKAQLYLTVNPAPRDMACQV
Sbjct: 1141 FQGYSSSGITEQTVTIKPYSLSSGETYVLQVSVASKHGLLGKAQLYLTVNPAPRDMACQV 1200
Query: 1201 QPHHGLEAHTVFSVFCMSGKPDFHYEFSYQIGNTSKHTLYHGRDTQYYFVLPAGEHLDNY 1260
QPHHGLEAHTVFSVFCMSGKPDFHYEFSYQIGNTSKHTLYHGRDTQYYFVLPAGEHLDNY
Sbjct: 1201 QPHHGLEAHTVFSVFCMSGKPDFHYEFSYQIGNTSKHTLYHGRDTQYYFVLPAGEHLDNY 1260
Query: 1261 KVMVSTEITDGKGSKVQPCTVVVTVLPRYHGNDCLGEDLYNSSLKNLSTLQLMGSYTEIR 1320
KVMVSTEITDGKGSKVQPCTVVVTVLPRYHGNDCLGEDLYNSSLKNLSTLQLMGSYTEIR
Sbjct: 1261 KVMVSTEITDGKGSKVQPCTVVVTVLPRYHGNDCLGEDLYNSSLKNLSTLQLMGSYTEIR 1320
Query: 1321 NYITVITRILSRLSKEDKTASCNQWSRIQDALISSVCRLAFVDQEEMIGSVLMLRDLVSF 1380
NYITVITRILSRLSKEDKTASCNQWSRIQDALISSVCRLAFVDQEEMIGSVLMLRDLVSF
Sbjct: 1321 NYITVITRILSRLSKEDKTASCNQWSRIQDALISSVCRLAFVDQEEMIGSVLMLRDLVSF 1380
Query: 1381 SNKLGFMSAVLILKYTRALLAQGQFSGPFVIDKGVRLELIGLISRVWEVSEQENSKEEVY 1440
SNKLGFMSAVLILKYTRALLAQGQFSGPFVIDKGVRLELIGLISRVWEVSEQENSKEEVY
Sbjct: 1381 SNKLGFMSAVLILKYTRALLAQGQFSGPFVIDKGVRLELIGLISRVWEVSEQENSKEEVY 1440
Query: 1441 RHEEGITVISDLLLGCLSLNHVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGDLAGHSP 1500
RHEEGITVISDLLLGCLSLNHVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGDLAGHSP
Sbjct: 1441 RHEEGITVISDLLLGCLSLNHVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGDLAGHSP 1500
Query: 1501 AGAETQSPCYISQLILFKKNPYPGSQAPGQIGGVVGLNLYTCSSRRPINRQWLRKPVMVE 1560
AGAETQSPCYISQLILFKKNPYPGSQAPGQIGGVVGLNLYTCSSRRPINRQWLRKPVMVE
Sbjct: 1501 AGAETQSPCYISQLILFKKNPYPGSQAPGQIGGVVGLNLYTCSSRRPINRQWLRKPVMVE 1560
Query: 1561 FGEEDGLDNRRNKTTFVLLRDKVNLHQFTELSENPQESLQIEIEFSKPVTRAFPVMLLVR 1620
FGEEDGLDNRRNKTTFVLLRDKVNLHQFTELSENPQESLQIEIEFSKPVTRAFPVMLLVR
Sbjct: 1561 FGEEDGLDNRRNKTTFVLLRDKVNLHQFTELSENPQESLQIEIEFSKPVTRAFPVMLLVR 1620
Query: 1621 FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKDASVGYLSLLDADYDRKPPNRYLAKAV 1680
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKDASVGYLSLLDADYDRKPPNRYLAKAV
Sbjct: 1621 FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKDASVGYLSLLDADYDRKPPNRYLAKAV 1680
Query: 1681 NYTVHFQWIRCLFWDKREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFEVSD 1740
NYTVHFQWIRCLFWDKREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFEVSD
Sbjct: 1681 NYTVHFQWIRCLFWDKREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFEVSD 1740
Query: 1741 ISKLQSHPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQLYAV 1800
ISKLQSHPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQLYAV
Sbjct: 1741 ISKLQSHPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQLYAV 1800
Query: 1801 VIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLR 1860
VIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLR
Sbjct: 1801 VIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLR 1860
Query: 1861 KIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTCLQGGLG 1920
KIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTCLQGGLG
Sbjct: 1861 KIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTCLQGGLG 1920
Query: 1921 FRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLLCVYACLTALVAAGGQE 1980
FRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLLCVYACLTALVAAGGQE
Sbjct: 1921 FRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLLCVYACLTALVAAGGQE 1980
Query: 1981 QPHLDVSPTLGSFRVGLLCTLLASPGAQLLSLLFRLSKEAPGSARVEPHSPLRGGAQTEA 2040
QPHLDVSPTLGSFRVGLLCTLLASPGAQLLSLLFRLSKEAPGSARVEPHSPLRGGAQTEA
Sbjct: 1981 QPHLDVSPTLGSFRVGLLCTLLASPGAQLLSLLFRLSKEAPGSARVEPHSPLRGGAQTEA 2040
Query: 2041 PHGPNSWGRIPDAQEPRKQPASAILSGSGRAQRKAASDNGTACPAPKLQVHGADHSRTSL 2100
PHGPNSWGRIPDAQEPRKQPASAILSGSGRAQRKAASDNGTACPAPKLQVHGADHSRTSL
Sbjct: 2041 PHGPNSWGRIPDAQEPRKQPASAILSGSGRAQRKAASDNGTACPAPKLQVHGADHSRTSL 2100
Query: 2101 MGKSHCCPPHTQAPSSGLEGLMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFG 2160
MGKSHCCPPHTQAPSSGLEGLMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFG
Sbjct: 2101 MGKSHCCPPHTQAPSSGLEGLMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFG 2160
Query: 2161 QEQCVQWLHLLSLSVVCCIFITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSEL 2220
QEQCVQWLHLLSLSVVCCIFITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSEL
Sbjct: 2161 QEQCVQWLHLLSLSVVCCIFITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSEL 2220
Query: 2221 AERSWTRLPFSSSCSIPDCAGEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRT 2280
AERSWTRLPFSSSCSIPDCAGEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRT
Sbjct: 2221 AERSWTRLPFSSSCSIPDCAGEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRT 2280
Query: 2281 RAALRDISMDILMLLLLLCVIYGRFSQDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDW 2340
RAALRDISMDILMLLLLLCVIYGRFSQDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDW
Sbjct: 2281 RAALRDISMDILMLLLLLCVIYGRFSQDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDW 2340
Query: 2341 SLTTLLDGLYPGGTPSARVPGAQPGALGGKCYLIGSSVIRQLKVFPRHLCKPPRPFSALI 2400
SLTTLLDGLYPGGTPSARVPGAQPGALGGKCYLIGSSVIRQLKVFPRHLCKPPRPFSALI
Sbjct: 2341 SLTTLLDGLYPGGTPSARVPGAQPGALGGKCYLIGSSVIRQLKVFPRHLCKPPRPFSALI 2400
Query: 2401 EDSIPTCSPEVGGPENPYLIDPENQNVTLNGPGGCGTREDCVLSLGRTRTEAHTALSRLR 2460
EDSIPTCSPEVGGPENPYLIDPENQNVTLNGPGGCGTREDCVLSLGRTRTEAHTALSRLR
Sbjct: 2401 EDSIPTCSPEVGGPENPYLIDPENQNVTLNGPGGCGTREDCVLSLGRTRTEAHTALSRLR 2460
Query: 2461 ASMWIDRSTRAVSVHFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQ 2520
ASMWIDRSTRAVSVHFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQ
Sbjct: 2461 ASMWIDRSTRAVSVHFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQ 2520
Query: 2521 YHLMLPQLVFLALSLIHLCVQLYRMMDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLV 2580
YHLMLPQLVFLALSLIHLCVQLYRMMDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLV
Sbjct: 2521 YHLMLPQLVFLALSLIHLCVQLYRMMDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLV 2580
Query: 2581 TLAGDVTNQFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCS 2640
TLAGDVTNQFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCS
Sbjct: 2581 TLAGDVTNQFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCS 2640
Query: 2641 SMMRHSLPSIFVAGLVGALMLAALSHLHRFLLSMWVLPPGTFTDAFPGLLFHFPRRSQKD 2700
SMMRHSLPSIFVAGLVGALMLAALSHLHRFLLSMWVLPPGTFTDAFPGLLFHFPRRSQKD
Sbjct: 2641 SMMRHSLPSIFVAGLVGALMLAALSHLHRFLLSMWVLPPGTFTDAFPGLLFHFPRRSQKD 2700
Query: 2701 CLLGLSKSDQRAMACYFGILLIVSATLCFGMLRGFLMTLPQKRKSFQSKSFVRLKDVTAY 2760
CLLGLSKSDQRAMACYFGILLIVSATLCFGMLRGFLMTLPQKRKSFQSKSFVRLKDVTAY
Sbjct: 2701 CLLGLSKSDQRAMACYFGILLIVSATLCFGMLRGFLMTLPQKRKSFQSKSFVRLKDVTAY 2760
Query: 2761 MWEKVLTFLRLETPKLEEAEMVENHNYYLDEFANLLDELLMKINGLSDSLQLPLLEKTSN 2820
MWEKVLTFLRLETPKLEEAEMVENHNYYLDEFANLLDELLMKINGLSDSLQLPLLEKTSN
Sbjct: 2761 MWEKVLTFLRLETPKLEEAEMVENHNYYLDEFANLLDELLMKINGLSDSLQLPLLEKTSN 2820
Query: 2821 NTGEARTEESPLVDISSYQAAEPADIKDF 2849
NTGEARTEESPLVDISSYQAAEPADIKDF
Sbjct: 2821 NTGEARTEESPLVDISSYQAAEPADIKDF 2849
>gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
Length = 2459
Score = 219 bits (557), Expect = 4e-56
Identities = 385/1737 (22%), Positives = 666/1737 (38%), Gaps = 283/1737 (16%)
Query: 1118 LSAGRAEPVLMIDW---------PKALLGRAVFQGYSSSGIT---EQTVTI---KPYSLS 1162
++ G PV M W + LL +G+ +T T T+ + S
Sbjct: 684 VTMGEDSPVAMFSWYLDNTPTEQAEPLLDACRLRGFWPRSLTLLQSNTSTLLLNSSFLQS 743
Query: 1163 SGETYVLQVSVASKHGLLGKAQLYLTVNPAPRDMACQVQPHHGLEAHTVFSVFCMSGKPD 1222
GE ++ + ++H G+ ++ P AC + P G T F++FC +
Sbjct: 744 RGEVIRIRATALTRHAY-GEDTYVISTVPPREVPACTIAPEEGTVL-TSFAIFCNASTAL 801
Query: 1223 FHYEFSYQIGNTSKHTLYHGRDTQYYFV-LPAGEHLDNYKVMVSTEITDGKGSKVQPCTV 1281
EF + + + S L+ G + V LP GE +++ + V T+ G Q +
Sbjct: 802 GPLEFCFCLESGS--CLHCGPEPALPSVYLPLGEENNDFVLTVVISATNRAGDTQQTQAM 859
Query: 1282 VVTVLPRYHGNDCLGEDLYNSSL--KNLSTLQLMGSYTEIRNYITVITRILSRLSKED-- 1337
L G+ C+ + + +++ K + LQ G ++ ++ +L++ +
Sbjct: 860 AKVAL----GDTCVEDVAFQAAVSEKIPTALQGEGGPEQLLQLAKAVSSMLNQEHESQGS 915
Query: 1338 -KTASCNQWSRIQDALISSVCRLA--FVDQEEMIGSVLMLRDLVSFSNKL---GFMSAVL 1391
++ S + ++++ ++ S+ + D + + +LR++ S +L A L
Sbjct: 916 GQSLSIDVRQKVREHVLGSLSAVTTGLEDVQRVQELAEVLREVTCRSKELTPSAQWEASL 975
Query: 1392 ILKY-TRALLAQGQFSGPFVIDKGVRLELIGLISRVWEVSEQENSKEEVYRHEEGITVIS 1450
L++ + ALL + P D+ + L V V E S E + I+
Sbjct: 976 ALQHASEALLTVSAKARPE--DQRRQAATRDLFQAVGSVLEASLSNRPEEPAEASSSQIA 1033
Query: 1451 DLLLGCLSLNHVSTGQMEFRTLLHYNLQSSVQSL---GSVQVHL----PGDLAGHS--PA 1501
+L + HV T TLL L + ++ S+ V+ P G S P
Sbjct: 1034 TVLRLLRVMEHVQT------TLLLGKLPGGLPAMLATPSISVYTNRIQPWSWQGSSLRPD 1087
Query: 1502 GAET-----------------QSPCYISQLILFKKNPYPGSQAPGQIGGVVGLNLYTCSS 1544
A++ Q P I +++ F K+P+P G V GL + + S
Sbjct: 1088 AADSATFMLPAASSLSSLEGGQEPVDI-KIMSFPKSPFPARSHFDVSGTVGGLRVTSPS- 1145
Query: 1545 RRPINRQWLRKPVMVEFGEEDGLDNRRNKTTFVLLRDKVNLHQFTELSENPQESLQIEIE 1604
G+ + N +L R Q T L+ E+L + +
Sbjct: 1146 -----------------GQLIPVKNLSENIEILLPRHSQRHSQPTVLNLTSPEALWVNVT 1188
Query: 1605 FSKPVTRA-------FPVMLLVRFSEKPTPSDF-----LVKQIYFWDESIVQIYIPAASQ 1652
+ + L + + P S + LV + DE I P +
Sbjct: 1189 SGEATLGIQLHWRPDIALTLSLGYGYHPNKSSYDAQTHLVPMVAP-DELPTWILSPQDLR 1247
Query: 1653 KDASVGYLSLL-DADYDRKPPNRYLAKAVNYTVHFQWIRCLFWDKRE--WKSERFSPQPG 1709
V YL+++ ++D + P + H C+FWD+ + W P
Sbjct: 1248 FGEGVYYLTVVPESDLEPAPGRDLTVGITTFLSH-----CVFWDEVQETWDDSGCQVGPR 1302
Query: 1710 TSPEKVNCSYHRLAAFALLRRKLKASFEVSDISKLQSHPENLLPSIFIMGSV-ILYGFLV 1768
TSP + +C + L F + + + ++L + E+ + +G + ++Y +V
Sbjct: 1303 TSPYQTHCLCNHLTFFGSTFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVV 1362
Query: 1769 AKSRQVDHHEKKKAGYIFLQEASLPGHQLYAVVIDTGFRAPARLTSKVYIVLCGDNGLSE 1828
+R+ D ++ K L++ Y V + TG R A +SKV + L G +G E
Sbjct: 1363 IWARRKDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGERE 1422
Query: 1829 TKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTG 1888
L+ P+ P+FER + F+LS LG LR +RLWHD+ G P W++S V+V +L
Sbjct: 1423 PHHLADPDTPVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMD 1482
Query: 1889 QGWFFPAQCWLSAGRHDGRVER--ELTCLQGGLGFRKLFYCKFTEYLEDFHVWLSVYSRP 1946
+ W+F WLS D +++ + Q F LF+ K + +D H+W S++SR
Sbjct: 1483 RKWYFLCNSWLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRC 1542
Query: 1947 SSSRYLHTPRLTVSFSLLCVYACLTALVAAGGQEQP---HLDVSP---TLGSFRVGLLCT 2000
+ S + R++ FSLL + LT+++ G + P +D+ T +GL +
Sbjct: 1543 ARSSFTRVQRVSCCFSLL-LCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESS 1601
Query: 2001 LLASPGAQLLSLLF-----RLSKEA------PGSARVEPH-SPLRGGAQT---------- 2038
+L P L+ +F R++KE GS + P P+ G T
Sbjct: 1602 ILMFPINLLIVQIFQNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSR 1661
Query: 2039 ----------------------------------EAPHGPNSWGRIPDAQEPRKQPASAI 2064
+ + N+ G++ + +++ +
Sbjct: 1662 IVSSLFKALKVPSPALGWDSVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTL 1721
Query: 2065 LSGSGRAQRKAASDNGTACPAPKLQVHG--------------ADH--SRTSLMGKSHCCP 2108
GS + K + CP PK G +H L+G
Sbjct: 1722 TLGSSEMKEK------SQCPKPKAARSGPWKDSAYRQCLYLQLEHVEQELRLVGPRGFSQ 1775
Query: 2109 PHTQAPS-------SGLEGLMP-QW----SRALQ--------PWWSSAV-WAICGTASLA 2147
PH+ A + G G+ P W + ALQ PWW V W + S
Sbjct: 1776 PHSHAQALRQLQTLKGGLGVQPGTWAPAHASALQVSKPPQGLPWWCILVGWLLVAATSGV 1835
Query: 2148 CSLGTGFLAYRFGQEQCVQWLHLLSLSVVCCIFITQPLMVCLMALGFAWKRRADNHFFTE 2207
+ T +G+ ++WL +++S V +F+TQPL V LGFA FF
Sbjct: 1836 AAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKV----LGFA-------AFFAL 1884
Query: 2208 SLCEATRDLDSELAERSWTRLPFSSSCSIPDCAGEVEKVLAARQQARHLRWAHPPSKAQL 2267
L + D T P PD A R +R + PP A +
Sbjct: 1885 VLKRVDDEED--------TVAPLPGHLLGPD---PYALFRARRNSSRDV--YQPPLTAAI 1931
Query: 2268 RGTRQRMRRESRTRAALRDISMDILMLLLLLCVIYGRFSQDEYSLNQAIRKEFTRNARNC 2327
+ +E + A +R+I + L +LL V YG+ Y LN+ ++ FTR
Sbjct: 1932 EKMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTRGFSGV 1991
Query: 2328 LGGLRNIADWWDWSLTTLLDGLYPGGTPSARVPGAQPGAL-GGKCYLIGSSVIRQLKVFP 2386
LG +++ W+ TTL+ LY G PG + G L+GS+ IRQ++V
Sbjct: 1992 LG----FREFFKWANTTLVSNLY----------GHPPGFITDGNSKLVGSAQIRQVRVQE 2037
Query: 2387 RH--LCKPPR--------PFSALIED--------SIPTCSPEVGGPENPYLIDPENQNVT 2428
L + P+ P+S ED + T S E Y + Q
Sbjct: 2038 SSCPLAQQPQAYLNGCRAPYSLDAEDMADYGEGWNATTLS------EWQYQSQDQRQGYP 2091
Query: 2429 LNGPGGCGTREDCVLSLGRTRTEAHTALSRLRASMWIDRSTRAVSVHFTLYNPPTQLFTS 2488
+ G V+ LG R L L + W+D TRAV V T+YN LF
Sbjct: 2092 IWGKLTVYRGGGYVVPLGTDRQSTSRILRYLFDNTWLDALTRAVFVESTVYNANVNLFCI 2151
Query: 2489 VSLRVEILPTGSLVPSSLVESFSIFRSDSALQYHLMLPQLVFLALSLIHLCVQLYRMMDK 2548
V+L +E G+ + ++S ++ ++ +L++ L ++ VQ R M K
Sbjct: 2152 VTLTLETSALGTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKR-MSK 2210
Query: 2549 GVLSYWRKPRNWLELSVVGVSLTYYAVSGHLVTLAGDVTNQFHRGLCRAFMDLTLMASWN 2608
Y+ N LEL+++ S + AV LA + Q R + + A+ +
Sbjct: 2211 ETWGYFCSKWNLLELAIILASWSALAVFVKRAVLA-ERDLQRCRNHREEGISFSETAAAD 2269
Query: 2609 QRARWLRGILLFLFTLKCVYLPGIQNTMASCSSMMRHSLPSIFVAGLVGALMLAALS 2665
++ L+ L T+K +L + M ++ +R + I +V ML A S
Sbjct: 2270 AALGYIIAFLVLLSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYS 2326
>gi|5174633 receptor for egg jelly-like protein precursor [Homo
sapiens]
Length = 2253
Score = 151 bits (381), Expect = 1e-35
Identities = 208/932 (22%), Positives = 364/932 (39%), Gaps = 91/932 (9%)
Query: 1741 ISKLQSHPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQL-YA 1799
I L +P L +FI ++LY L + D ++ G++ + + P L Y
Sbjct: 1177 IKSLHQNPVTLFTVLFI---ILLYVGLAFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYL 1233
Query: 1800 VVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLL 1859
V I TG R + + V++ L G S+ LS P R S +TF+L+ + LG +
Sbjct: 1234 VTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLGDI 1293
Query: 1860 RKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVER--ELTCLQG 1917
IR+WH++ G SP W++S + V+ L + W F Q WLS D ++R +T
Sbjct: 1294 HSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSV---DTTLDRTFHVTHPDE 1350
Query: 1918 GLGFRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFS-LLCVYACLTALVAA 1976
L + F+ + L H+W S+++ + + RL+ + LL C
Sbjct: 1351 RLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQRLSCCLAMLLSSLLCNIMFFNL 1410
Query: 1977 GGQEQPHLDVSPTLGSFRVGLLCTLLASPGAQLLSLLFRLSKEAPGSARVEPHSPLRGGA 2036
QEQ + S +G+ L+ P L++ LF S+ P A ++ SP +
Sbjct: 1411 NRQEQTESRERKYMRSMMIGIESVLITIPVQLLITFLFTCSQRKP-QADLKEVSPQKHPL 1469
Query: 2037 QTEAPHGPNSWGRIPDAQEPRKQPASAILSGSGRAQRKAASDNGTACPAPKLQVHGADHS 2096
+EA + R A E K + + + + + + A PK + A
Sbjct: 1470 MSEASEHWEEYLRKWHAYETAKVHPREVAKPASKGKPRLPKASPKATSKPKHRHRKAQIK 1529
Query: 2097 RTSLMGKSHCCPPH---------TQAPSSGLEGLMPQWSRALQPWWSSAV-WAICGTASL 2146
+G + + Q PS + + R + PWW V W + S
Sbjct: 1530 TPETLGPNTNSNNNIEDDQDVHSEQHPSQKDLQQLKKKPRIVLPWWCVYVAWFLVFATSS 1589
Query: 2147 ACSLGTGFLAYRFGQEQCVQWLHLLSLSVVCCIFITQPLMVCLMALGFAWKRRADNHFFT 2206
S F +G ++ ++WL S + + QP + L++ GF R + +
Sbjct: 1590 ISSFFIVFYGLTYGYDKSIEWLFASFCSFCQSVLLVQPSKIILLS-GF----RTNKPKYC 1644
Query: 2207 ESLCEATRDLDSELAERSWTRLPFSSSCSIPDCAGEVEKVLAARQQARHLRWAHPPSKAQ 2266
++L +T+ +T + P+ E++++ + R R P ++ +
Sbjct: 1645 KNLSWSTK--------YKYTEIRLDGMRMHPE---EMQRIHDQIVRIRGTRMYQPLTEDE 1693
Query: 2267 LRGTRQRMRRESRTRAALRDISMDILMLLLLLCVIYGRFSQDEYSLNQAIRKEFTRNARN 2326
+R +++ R + R L I + L LLL +I D + NQ IR F+ +
Sbjct: 1694 IRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTDCFYYNQFIRDRFSMD--- 1750
Query: 2327 CLGGLRNIADWWDWSLTTLLDGLYPGGTPSARVPGAQPGALGGKCYLIGSSVIRQLKV-F 2385
L + + D + W + LL L+ P+ + ++G ++RQ++
Sbjct: 1751 -LATVTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSK--------ILGLPLMRQVRAKS 1801
Query: 2386 PRHLCKPPRPFSALIEDSIPT---CSPEVG-GPE---------------------NPYLI 2420
+C P F +++SI C P+ G PE N +
Sbjct: 1802 SEKMCLPAEKF---VQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNGFTY 1858
Query: 2421 DPENQNVTLNGPGGCGTREDCVLSL----GRTRTEAHTALSRLRASMWIDRSTRAVSVHF 2476
P+ G T +L + R + L L+ S W+D T AV +
Sbjct: 1859 KPQGTQWLYYSYGLLHTYGSGGYALYFFPEQQRFNSTLRLKELQESNWLDEKTWAVVLEL 1918
Query: 2477 TLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIF---RSDSALQYHLMLPQLVFLAL 2533
T +NP LF S+S+ E+ G + S + SFS+ R SA Y + + FLA
Sbjct: 1919 TTFNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLAY 1978
Query: 2534 SLIHLCVQLYRMMDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLVTLAGDVTNQFHRG 2593
+ C+ + SY R N L ++ + + LA + +F+
Sbjct: 1979 VVDEGCIIMQER-----ASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGII-RFYLS 2032
Query: 2594 LCRAFMDLTLMASWNQRARWLRGILLFLFTLK 2625
F+ ++ + R + G LLFL LK
Sbjct: 2033 NPEDFIPFHAVSQVDHIMRIILGFLLFLTILK 2064
>gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens]
Length = 1731
Score = 122 bits (305), Expect = 7e-27
Identities = 78/280 (27%), Positives = 127/280 (45%), Gaps = 5/280 (1%)
Query: 1690 RCLFWD--KREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFEVSDISKLQSH 1747
+C +W+ + W S P ++ + C + L FA + + V D KL
Sbjct: 634 QCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLR 693
Query: 1748 PENLLPSIFIMGSVI-LYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQLYAVVIDTGF 1806
N + ++ S++ Y V +R+ D + +K L + Y + + TG+
Sbjct: 694 VTNNPVGVSLLASLLGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGY 753
Query: 1807 RAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWH 1866
R A T+KV I L G G SE L P+K +FER F+L+ LG L +RLWH
Sbjct: 754 RRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWH 813
Query: 1867 DSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTCLQGG--LGFRKL 1924
D+ G SP W++S V+V ++ + W F CWL+ D ++R + FR L
Sbjct: 814 DNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVSKRELFSFRHL 873
Query: 1925 FYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLL 1964
F E ++WLS+ +R +++ RL+ +LL
Sbjct: 874 FSSMIVEKFTQDYLWLSIATRHPWNQFTRVQRLSCCMTLL 913
Score = 61.2 bits (147), Expect = 1e-08
Identities = 60/235 (25%), Positives = 98/235 (41%), Gaps = 28/235 (11%)
Query: 2116 SGLEGLMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFGQEQCVQWLHLLSLSV 2175
S EG P S L W +S W + G SLA + T + ++Q W+ + LSV
Sbjct: 1137 SSEEGKKPI-SNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSV 1195
Query: 2176 VCCIFITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSELAERSWTRLPFSSSCS 2235
+ IFI+QP+ V ++ E+ E T+ + + LA+ S S
Sbjct: 1196 LQNIFISQPVKVVFFTFLYSLMMSRMPRLNKEN--EXTKRILALLAK---------CSSS 1244
Query: 2236 IPDCAGEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRTRAALRDISMDILMLL 2295
+P + V A A + HP +R ++ + DI + IL L
Sbjct: 1245 VPGSRDKNNPVYVA--PAINSPTKHP----------ERTLKKKKLFKLTGDILVQILFLT 1292
Query: 2296 LLLCVIYGRFSQDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDWSLTTLLDGLY 2350
LL+ IY + + + L+QAI K F+ ++ + D++ W+ LL LY
Sbjct: 1293 LLMTAIYSAKNSNRFYLHQAIWKTFSHQ----FSEIKLLQDFYPWANHILLPSLY 1343
>gi|31559825 polycystin 1-like 3 [Homo sapiens]
Length = 1732
Score = 122 bits (305), Expect = 7e-27
Identities = 78/280 (27%), Positives = 127/280 (45%), Gaps = 5/280 (1%)
Query: 1690 RCLFWD--KREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFEVSDISKLQSH 1747
+C +W+ + W S P ++ + C + L FA + + V D KL
Sbjct: 634 QCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLR 693
Query: 1748 PENLLPSIFIMGSVI-LYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQLYAVVIDTGF 1806
N + ++ S++ Y V +R+ D + +K L + Y + + TG+
Sbjct: 694 VTNNPVGVSLLASLLGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGY 753
Query: 1807 RAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWH 1866
R A T+KV I L G G SE L P+K +FER F+L+ LG L +RLWH
Sbjct: 754 RRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWH 813
Query: 1867 DSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTCLQGG--LGFRKL 1924
D+ G SP W++S V+V ++ + W F CWL+ D ++R + FR L
Sbjct: 814 DNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVSKRELFSFRHL 873
Query: 1925 FYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLL 1964
F E ++WLS+ +R +++ RL+ +LL
Sbjct: 874 FSSMIVEKFTQDYLWLSIATRHPWNQFTRVQRLSCCMTLL 913
Score = 61.6 bits (148), Expect = 1e-08
Identities = 59/237 (24%), Positives = 96/237 (40%), Gaps = 31/237 (13%)
Query: 2116 SGLEGLMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFGQEQCVQWLHLLSLSV 2175
S EG P S L W +S W + G SLA + T + ++Q W+ + LSV
Sbjct: 1137 SSEEGKKPI-SNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSV 1195
Query: 2176 VCCIFITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSELAERSWTRLPFSSSC- 2234
+ IFI+QP+ V F + L+ E +++ L + C
Sbjct: 1196 LQNIFISQPVKVVFFT------------FLYSLMMSRMPRLNKENEQQTKRILALLAKCS 1243
Query: 2235 -SIPDCAGEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRTRAALRDISMDILM 2293
S+P + V A A + HP +R ++ + DI + IL
Sbjct: 1244 SSVPGSRDKNNPVYVA--PAINSPTKHP----------ERTLKKKKLFKLTGDILVQILF 1291
Query: 2294 LLLLLCVIYGRFSQDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDWSLTTLLDGLY 2350
L LL+ IY + + + L+QAI K F+ ++ + D++ W+ LL LY
Sbjct: 1292 LTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ----FSEIKLLQDFYPWANHILLPSLY 1344
>gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo
sapiens]
Length = 1732
Score = 121 bits (304), Expect = 9e-27
Identities = 78/280 (27%), Positives = 127/280 (45%), Gaps = 5/280 (1%)
Query: 1690 RCLFWD--KREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFEVSDISKLQSH 1747
+C +W+ + W S P ++ + C + L FA + + V D KL
Sbjct: 634 QCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLR 693
Query: 1748 PENLLPSIFIMGSVI-LYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQLYAVVIDTGF 1806
N + ++ S++ Y V +R+ D + +K L + Y + + TG+
Sbjct: 694 VTNNPVGVSLLASLLGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGY 753
Query: 1807 RAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWH 1866
R A T+KV I L G G SE L P+K +FER F+L+ LG L +RLWH
Sbjct: 754 RRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWH 813
Query: 1867 DSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTCLQGG--LGFRKL 1924
D+ G SP W++S V+V ++ + W F CWL+ D ++R + FR L
Sbjct: 814 DNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVSKRELFSFRHL 873
Query: 1925 FYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLL 1964
F E ++WLS+ +R +++ RL+ +LL
Sbjct: 874 FSSMIVEKFTQDYLWLSIATRHPWNQFTRIQRLSCCMTLL 913
Score = 60.8 bits (146), Expect = 2e-08
Identities = 59/237 (24%), Positives = 95/237 (40%), Gaps = 31/237 (13%)
Query: 2116 SGLEGLMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFGQEQCVQWLHLLSLSV 2175
S EG P S L W +S W + G SLA + T ++Q W+ + LSV
Sbjct: 1137 SSEEGKKPI-SNGLSKWLTSVCWLLLGFTSLASAFFTALYRLELSKDQATSWMISIILSV 1195
Query: 2176 VCCIFITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSELAERSWTRLPFSSSC- 2234
+ IFI+QP+ V F + L+ E +++ L + C
Sbjct: 1196 LQNIFISQPVKVVFFT------------FLYSLMMSRMPRLNKENEQQTKRILALLAKCS 1243
Query: 2235 -SIPDCAGEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRTRAALRDISMDILM 2293
S+P + V A A + HP +R ++ + DI + IL
Sbjct: 1244 SSVPGSRDKNNPVYVA--PAINSPTKHP----------ERTLKKKKLFKLTGDILVQILF 1291
Query: 2294 LLLLLCVIYGRFSQDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDWSLTTLLDGLY 2350
L LL+ IY + + + L+QAI K F+ ++ + D++ W+ LL LY
Sbjct: 1292 LTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ----FSEIKLLQDFYPWANHILLPSLY 1344
>gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo
sapiens]
Length = 1731
Score = 121 bits (304), Expect = 9e-27
Identities = 78/280 (27%), Positives = 127/280 (45%), Gaps = 5/280 (1%)
Query: 1690 RCLFWD--KREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFEVSDISKLQSH 1747
+C +W+ + W S P ++ + C + L FA + + V D KL
Sbjct: 634 QCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLR 693
Query: 1748 PENLLPSIFIMGSVI-LYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQLYAVVIDTGF 1806
N + ++ S++ Y V +R+ D + +K L + Y + + TG+
Sbjct: 694 VTNNPVGVSLLASLLGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGY 753
Query: 1807 RAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWH 1866
R A T+KV I L G G SE L P+K +FER F+L+ LG L +RLWH
Sbjct: 754 RRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWH 813
Query: 1867 DSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTCLQGG--LGFRKL 1924
D+ G SP W++S V+V ++ + W F CWL+ D ++R + FR L
Sbjct: 814 DNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVSKRELFSFRHL 873
Query: 1925 FYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLL 1964
F E ++WLS+ +R +++ RL+ +LL
Sbjct: 874 FSSMIVEKFTQDYLWLSIATRHPWNQFTRIQRLSCCMTLL 913
Score = 61.2 bits (147), Expect = 1e-08
Identities = 60/235 (25%), Positives = 98/235 (41%), Gaps = 28/235 (11%)
Query: 2116 SGLEGLMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFGQEQCVQWLHLLSLSV 2175
S EG P S L W +S W + G SLA + T + ++Q W+ + LSV
Sbjct: 1137 SSEEGKKPI-SNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSV 1195
Query: 2176 VCCIFITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSELAERSWTRLPFSSSCS 2235
+ IFI+QP+ V ++ E+ E T+ + + LA+ S S
Sbjct: 1196 LQNIFISQPVKVVFFTFLYSLMMSRMPRLNKEN--EXTKRILALLAK---------CSSS 1244
Query: 2236 IPDCAGEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRTRAALRDISMDILMLL 2295
+P + V A A + HP +R ++ + DI + IL L
Sbjct: 1245 VPGSRDKNNPVYVA--PAINSPTKHP----------ERTLKKKKLFKLTGDILVQILFLT 1292
Query: 2296 LLLCVIYGRFSQDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDWSLTTLLDGLY 2350
LL+ IY + + + L+QAI K F+ ++ + D++ W+ LL LY
Sbjct: 1293 LLMTAIYSAKNSNRFYLHQAIWKTFSHQ----FSEIKLLQDFYPWANHILLPSLY 1343
>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
Length = 4302
Score = 121 bits (303), Expect = 1e-26
Identities = 99/367 (26%), Positives = 163/367 (44%), Gaps = 39/367 (10%)
Query: 1680 VNYTVHFQWIR-----------CLFWDKRE--WKSERFSPQPGTSPEKVNCSYHRLAAFA 1726
+N + HF+W C ++ + + W++E P TSP + C L AF
Sbjct: 2993 LNLSSHFRWSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFG 3052
Query: 1727 LLRRKLKASFEVSDISKLQSHPE-----NLLPSIFIMGSVILYGFLVAKSRQVDHHEKKK 1781
AS V PE N + + ++ Y + A ++D + +
Sbjct: 3053 -------ASLFVPPSHVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASR 3105
Query: 1782 AGYIFLQEASLPGHQLYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFE 1841
I G Y +++ TG+ + T+ V I+L G + S + L F
Sbjct: 3106 GRAIPF--CGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA--FH 3161
Query: 1842 RNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLS- 1900
RNS F ++ P LG + KIR+WHD++G SP WF+ HV+V++L T + FF WLS
Sbjct: 3162 RNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSV 3221
Query: 1901 -AGRHDGRVERELTCLQGG--LGFRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRL 1957
+ G VE+E+ L FR+L + D H+WLS++ RP SR+ R
Sbjct: 3222 ETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRA 3281
Query: 1958 TVSFSLLCVYACLTAL----VAAGGQEQPHLD-VSP-TLGSFRVGLLCTLLASPGAQLLS 2011
T L+C++ A+ V H+ +SP ++ + VGL+ +++ P +
Sbjct: 3282 TCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAIL 3341
Query: 2012 LLFRLSK 2018
LFR+S+
Sbjct: 3342 FLFRMSR 3348
Score = 85.1 bits (209), Expect = 9e-16
Identities = 97/373 (26%), Positives = 154/373 (41%), Gaps = 26/373 (6%)
Query: 473 HHFPSIPSYNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTV-FATDTDITFTAVTK 531
H FP + + VS + V +QA + V + + V AT T+ FTA +
Sbjct: 1938 HSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCCEPGIATGTERNFTARVQ 1997
Query: 532 ETIPLEFEWYFG-----EDPPVRTTSRSIKKRLSIPQWYRVMVKASNRMSSVVSEPHVIR 586
+ + WYF D V + R + + V+A N + S + V+
Sbjct: 1998 RGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQVRAFNALGSE-NRTLVLE 2056
Query: 587 VQKKIVANRLTSPSSALVNASVAFECWINFGTD-VAYLWDFGDGTVSLGSSS--SSHVYS 643
VQ + L S N S FE + VAY WDFGDG+ + + H Y
Sbjct: 2057 VQDAVQYVALQS-GPCFTNRSAQFEAATSPSPRRVAYHWDFGDGSPGQDTDEPRAEHSYL 2115
Query: 644 REGEFTVEVLAFNNVSASTLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEA 703
R G++ V+V A N VS + + + C+ P V + P +V + RSQ R +
Sbjct: 2116 RPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVLMRRSQ--RNYLEAHV 2173
Query: 704 AVFCDISQGLSYTWNL-----MDSEGLP--VSLPAAVDTHRQTLILPSHTLEYGNYTALA 756
+ ++ Y W + G P V+LP VD R L+LP L G+Y +
Sbjct: 2174 DLRDCVTYQTEYRWEVYRTASCQRPGRPARVALP-GVDVSRPRLVLPRLALPVGHYCFVF 2232
Query: 757 KVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRTTSSPIVLRGTQSFDP---DDP 813
V + + + + V + V +I G++ +S T +VL G++S+DP D
Sbjct: 2233 VVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRD--LVLDGSESYDPNLEDGD 2290
Query: 814 GATLRYHWECATA 826
L +HW C +
Sbjct: 2291 QTPLSFHWACVAS 2303
Score = 73.9 bits (180), Expect = 2e-12
Identities = 139/592 (23%), Positives = 213/592 (35%), Gaps = 102/592 (17%)
Query: 2121 LMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFGQEQCVQWLHLLSLSVVCCIF 2180
L+P W +L S + A+ S G++ F V WL S S +
Sbjct: 3548 LLPAWCASLAHGLSLLLVAVAVAVS-------GWVGASFPPGVSVAWLLSSSASFLASFL 3600
Query: 2181 ITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSELAERSWTRLPFSSSCSIPDCA 2240
+PL V L AL F+ + D D L E S ++ +
Sbjct: 3601 GWEPLKVLLEALYFSLVAK-----------RLHPDEDDTLVE----------SPAVTPVS 3639
Query: 2241 GEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRTRAALRDISMDILMLLLLLCV 2300
V +V PP L ++ R+ R LR + + +L LL+ L
Sbjct: 3640 ARVPRV-------------RPPHGFALFLAKEEARKVKRLHGMLRSLLVYMLFLLVTLLA 3686
Query: 2301 IYGRFS--QDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDWSLTTLLDGLYPGGTPSAR 2358
YG S Y L AI++E ++R L R+ + W W LL Y G S+
Sbjct: 3687 SYGDASCHGHAYRLQSAIKQEL--HSRAFLAITRS-EELWPWMAHVLLP--YVHGNQSSP 3741
Query: 2359 VPGAQPGALGGKCYLIGSSVIRQLKVFPRHLCKPPRPFSALIEDSIPTCSPEVGGPENPY 2418
+G +RQ+++ PP P + TCS G + Y
Sbjct: 3742 E--------------LGPPRLRQVRLQEALYPDPPGP-------RVHTCSAAGGFSTSDY 3780
Query: 2419 LI---DPENQNVT--LNGP--------GGCGTRED--CVLSLGRTRTEAHTALSRLRASM 2463
+ P N + T + P G C + V LG + E+ L L+
Sbjct: 3781 DVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHN 3840
Query: 2464 WIDRSTRAVSVHFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQYHL 2523
W+D +RAV + T Y+P L +V+LR+E G + + V F++ R + L L
Sbjct: 3841 WLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPL 3900
Query: 2524 MLPQLVFLALSLIHLCVQLYRMMDKGVLSYWRKPR--NWLELSVVGVSLTYYAVSGHLVT 2581
+ V L L +H V R + WR R W +V ++ V +
Sbjct: 3901 LTS--VCLLLFAVHFAVAEARTWHRE--GRWRVLRLGAWARWLLVALTAATALVRLAQLG 3956
Query: 2582 LAGDVTNQFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCSS 2641
A +F RG R F +A + AR L LLFL +K +
Sbjct: 3957 AADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGK 4016
Query: 2642 MMRHSLPSIFVAGLVGALMLAALSHLHRFLL-----SMW-------VLPPGT 2681
+ +LP + L ++ A + L L+ S+W VL PGT
Sbjct: 4017 TLCRALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGT 4068
Score = 61.6 bits (148), Expect = 1e-08
Identities = 55/232 (23%), Positives = 97/232 (41%), Gaps = 20/232 (8%)
Query: 442 VSAFMNSSSVHEDEVLVFADSQVN---QKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWH 498
++A++ + H F D N + V H+F ++ ++ + ++V + +
Sbjct: 1313 LTAYVTGNPAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFT 1372
Query: 499 SMTVWYKMQSVSVYTNGTVFATDTDITFTAVTKETIPLEFEWYFG--EDPPVRTTSRSIK 556
S+ V ++ +V++ + A P + W FG E P R +
Sbjct: 1373 SICVEPEVGNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVT 1432
Query: 557 KRLSIPQWYRVMVKASNRMSSVVSEPHVIRVQKKIVANRLTSPSSALVNASVAFECW--- 613
P Y V V ASN +S+ ++ ++ VQ+ ++ +S VN S+ E
Sbjct: 1433 FIYRDPGSYLVTVTASNNISAA-NDSALVEVQEPVLV------TSIKVNGSLGLELQQPY 1485
Query: 614 ----INFGTDVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSAS 661
+ G +YLWD GDG L +H Y+ G+FTV V +N VS S
Sbjct: 1486 LFSAVGRGRPASYLWDLGDGG-WLEGPEVTHAYNSTGDFTVRVAGWNEVSRS 1536
Score = 46.2 bits (108), Expect = 5e-04
Identities = 73/328 (22%), Positives = 126/328 (38%), Gaps = 46/328 (14%)
Query: 471 VIHHFPSIPSYNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTVFATDTDITFTAVT 530
V H + S + V +V S+AW ++TV +++ + V + TV + ++F+
Sbjct: 1513 VTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVVPLNGSVSFSTSL 1572
Query: 531 KETIPLEFEWYFGE-------DPPVRTTSRSIKKRLSIPQWYRVMVKASNRMSSVVSEPH 583
+ + + W + P + T RS+ + ++V A N + S
Sbjct: 1573 EAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGT-------FNIIVTAENEVGSAQDSIF 1625
Query: 584 VIRVQ----KKIVANRLTSPSSALVNASVAFECWINFGTDVAYLW----DFGDGTVSLGS 635
V +Q ++V P+ N +V + + GT+V+Y W D G G
Sbjct: 1626 VYVLQLIEGLQVVGGGRYFPT----NHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSGK 1681
Query: 636 SSSSHVYSREGEFTVEVLAFNNVSASTLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPV 695
S V G + V++ A N + ++ C V+ +G V P
Sbjct: 1682 GFSLTVL-EAGTYHVQLRATNMLGSA---------WADCTMDFVEPVGWLMVAA-SPNPA 1730
Query: 696 RLGVTFEAAVFCDISQGLSYTWNLMDSEGLPVSLPAAVDTHR-QTLILPSHTLEYGN--Y 752
+ + + G+ YTW+L EGL TH T L T+ GN
Sbjct: 1731 AVNTSVTLSAELAGGSGVVYTWSL--EEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLG 1788
Query: 753 TALAKVQIEGSVVYSNYCVGLEVRAQAP 780
+A A V+++ V S GL +RA P
Sbjct: 1789 SANATVEVDVQVPVS----GLSIRASEP 1812
Score = 44.7 bits (104), Expect = 0.001
Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 21/223 (9%)
Query: 471 VIHHFPSIPSYNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTVFATDTDITFTAVT 530
V+H + + Y ++ ++ + ++V + SV+V + V +TF
Sbjct: 1091 VMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVAGRPVTFYP-- 1148
Query: 531 KETIP----LEFEWYFGEDPPVRTTSRSIKKRLSIPQW-YRVMVKASNRMSSVVSEPHVI 585
+P + + W FG+ PV T S+ + Y V ++ +N +S ++ V
Sbjct: 1149 -HPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGAAAQADV- 1206
Query: 586 RVQKKIVANRLTSPSSALVNASVAFECWINFGTDVAYLWDFGDGTVSLGSSSS-SHVYSR 644
RV +++ + + A V + G ++ + +D GDGTV G ++ HVY R
Sbjct: 1207 RVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATVEHVYLR 1266
Query: 645 EGEFTVEVLAFNNVS--ASTLRQQLFIV---------CEPCQP 676
TV V A + A +L +F++ C P QP
Sbjct: 1267 AQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQP 1309
Score = 38.9 bits (89), Expect = 0.073
Identities = 50/199 (25%), Positives = 80/199 (40%), Gaps = 36/199 (18%)
Query: 565 YRVMVKASNRMSSVVSEPHVI--RVQKKIVANRLTSPSSALVNASVAFECWI--NFGTDV 620
+++ + ASN +S+V +V R+ + T P+ NA++A + + +V
Sbjct: 992 FKLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEV 1051
Query: 621 AYLWDFGDGTVSLG----------------------SSSSSHVYSREGEFTVEVLAFNNV 658
A+LW FGDG +L + H Y+ GE+ + VLA N
Sbjct: 1052 AFLWTFGDGEQALHQFQPPYNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASN-- 1109
Query: 659 SASTLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEAAVFCDISQGLSYTWN 718
+ L QQ+ + P + + G + R VTF G+ YTW+
Sbjct: 1110 AFENLTQQVPVSVRASLPSVAVGVSDGVLVAGRP------VTFYPHPL-PSPGGVLYTWD 1162
Query: 719 LMD-SEGLPVSLPAAVDTH 736
D S L S PAA T+
Sbjct: 1163 FGDGSPVLTQSQPAANHTY 1181
>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
Length = 4303
Score = 121 bits (303), Expect = 1e-26
Identities = 99/367 (26%), Positives = 163/367 (44%), Gaps = 39/367 (10%)
Query: 1680 VNYTVHFQWIR-----------CLFWDKRE--WKSERFSPQPGTSPEKVNCSYHRLAAFA 1726
+N + HF+W C ++ + + W++E P TSP + C L AF
Sbjct: 2993 LNLSSHFRWSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFG 3052
Query: 1727 LLRRKLKASFEVSDISKLQSHPE-----NLLPSIFIMGSVILYGFLVAKSRQVDHHEKKK 1781
AS V PE N + + ++ Y + A ++D + +
Sbjct: 3053 -------ASLFVPPSHVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASR 3105
Query: 1782 AGYIFLQEASLPGHQLYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFE 1841
I G Y +++ TG+ + T+ V I+L G + S + L F
Sbjct: 3106 GRAIPF--CGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRA--FH 3161
Query: 1842 RNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLS- 1900
RNS F ++ P LG + KIR+WHD++G SP WF+ HV+V++L T + FF WLS
Sbjct: 3162 RNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSV 3221
Query: 1901 -AGRHDGRVERELTCLQGG--LGFRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRL 1957
+ G VE+E+ L FR+L + D H+WLS++ RP SR+ R
Sbjct: 3222 ETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRA 3281
Query: 1958 TVSFSLLCVYACLTAL----VAAGGQEQPHLD-VSP-TLGSFRVGLLCTLLASPGAQLLS 2011
T L+C++ A+ V H+ +SP ++ + VGL+ +++ P +
Sbjct: 3282 TCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAIL 3341
Query: 2012 LLFRLSK 2018
LFR+S+
Sbjct: 3342 FLFRMSR 3348
Score = 85.1 bits (209), Expect = 9e-16
Identities = 97/373 (26%), Positives = 154/373 (41%), Gaps = 26/373 (6%)
Query: 473 HHFPSIPSYNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTV-FATDTDITFTAVTK 531
H FP + + VS + V +QA + V + + V AT T+ FTA +
Sbjct: 1938 HSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCCEPGIATGTERNFTARVQ 1997
Query: 532 ETIPLEFEWYFG-----EDPPVRTTSRSIKKRLSIPQWYRVMVKASNRMSSVVSEPHVIR 586
+ + WYF D V + R + + V+A N + S + V+
Sbjct: 1998 RGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQVRAFNALGSE-NRTLVLE 2056
Query: 587 VQKKIVANRLTSPSSALVNASVAFECWINFGTD-VAYLWDFGDGTVSLGSSS--SSHVYS 643
VQ + L S N S FE + VAY WDFGDG+ + + H Y
Sbjct: 2057 VQDAVQYVALQS-GPCFTNRSAQFEAATSPSPRRVAYHWDFGDGSPGQDTDEPRAEHSYL 2115
Query: 644 REGEFTVEVLAFNNVSASTLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEA 703
R G++ V+V A N VS + + + C+ P V + P +V + RSQ R +
Sbjct: 2116 RPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVLMRRSQ--RNYLEAHV 2173
Query: 704 AVFCDISQGLSYTWNL-----MDSEGLP--VSLPAAVDTHRQTLILPSHTLEYGNYTALA 756
+ ++ Y W + G P V+LP VD R L+LP L G+Y +
Sbjct: 2174 DLRDCVTYQTEYRWEVYRTASCQRPGRPARVALP-GVDVSRPRLVLPRLALPVGHYCFVF 2232
Query: 757 KVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRTTSSPIVLRGTQSFDP---DDP 813
V + + + + V + V +I G++ +S T +VL G++S+DP D
Sbjct: 2233 VVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRD--LVLDGSESYDPNLEDGD 2290
Query: 814 GATLRYHWECATA 826
L +HW C +
Sbjct: 2291 QTPLSFHWACVAS 2303
Score = 73.9 bits (180), Expect = 2e-12
Identities = 139/592 (23%), Positives = 213/592 (35%), Gaps = 102/592 (17%)
Query: 2121 LMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFGQEQCVQWLHLLSLSVVCCIF 2180
L+P W +L S + A+ S G++ F V WL S S +
Sbjct: 3549 LLPAWCASLAHGLSLLLVAVAVAVS-------GWVGASFPPGVSVAWLLSSSASFLASFL 3601
Query: 2181 ITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSELAERSWTRLPFSSSCSIPDCA 2240
+PL V L AL F+ + D D L E S ++ +
Sbjct: 3602 GWEPLKVLLEALYFSLVAK-----------RLHPDEDDTLVE----------SPAVTPVS 3640
Query: 2241 GEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRTRAALRDISMDILMLLLLLCV 2300
V +V PP L ++ R+ R LR + + +L LL+ L
Sbjct: 3641 ARVPRV-------------RPPHGFALFLAKEEARKVKRLHGMLRSLLVYMLFLLVTLLA 3687
Query: 2301 IYGRFS--QDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDWSLTTLLDGLYPGGTPSAR 2358
YG S Y L AI++E ++R L R+ + W W LL Y G S+
Sbjct: 3688 SYGDASCHGHAYRLQSAIKQEL--HSRAFLAITRS-EELWPWMAHVLLP--YVHGNQSSP 3742
Query: 2359 VPGAQPGALGGKCYLIGSSVIRQLKVFPRHLCKPPRPFSALIEDSIPTCSPEVGGPENPY 2418
+G +RQ+++ PP P + TCS G + Y
Sbjct: 3743 E--------------LGPPRLRQVRLQEALYPDPPGP-------RVHTCSAAGGFSTSDY 3781
Query: 2419 LI---DPENQNVT--LNGP--------GGCGTRED--CVLSLGRTRTEAHTALSRLRASM 2463
+ P N + T + P G C + V LG + E+ L L+
Sbjct: 3782 DVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHN 3841
Query: 2464 WIDRSTRAVSVHFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQYHL 2523
W+D +RAV + T Y+P L +V+LR+E G + + V F++ R + L L
Sbjct: 3842 WLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPL 3901
Query: 2524 MLPQLVFLALSLIHLCVQLYRMMDKGVLSYWRKPR--NWLELSVVGVSLTYYAVSGHLVT 2581
+ V L L +H V R + WR R W +V ++ V +
Sbjct: 3902 LTS--VCLLLFAVHFAVAEARTWHRE--GRWRVLRLGAWARWLLVALTAATALVRLAQLG 3957
Query: 2582 LAGDVTNQFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCSS 2641
A +F RG R F +A + AR L LLFL +K +
Sbjct: 3958 AADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGK 4017
Query: 2642 MMRHSLPSIFVAGLVGALMLAALSHLHRFLL-----SMW-------VLPPGT 2681
+ +LP + L ++ A + L L+ S+W VL PGT
Sbjct: 4018 TLCRALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGT 4069
Score = 61.6 bits (148), Expect = 1e-08
Identities = 55/232 (23%), Positives = 97/232 (41%), Gaps = 20/232 (8%)
Query: 442 VSAFMNSSSVHEDEVLVFADSQVN---QKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWH 498
++A++ + H F D N + V H+F ++ ++ + ++V + +
Sbjct: 1313 LTAYVTGNPAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFT 1372
Query: 499 SMTVWYKMQSVSVYTNGTVFATDTDITFTAVTKETIPLEFEWYFG--EDPPVRTTSRSIK 556
S+ V ++ +V++ + A P + W FG E P R +
Sbjct: 1373 SICVEPEVGNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVT 1432
Query: 557 KRLSIPQWYRVMVKASNRMSSVVSEPHVIRVQKKIVANRLTSPSSALVNASVAFECW--- 613
P Y V V ASN +S+ ++ ++ VQ+ ++ +S VN S+ E
Sbjct: 1433 FIYRDPGSYLVTVTASNNISAA-NDSALVEVQEPVLV------TSIKVNGSLGLELQQPY 1485
Query: 614 ----INFGTDVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSAS 661
+ G +YLWD GDG L +H Y+ G+FTV V +N VS S
Sbjct: 1486 LFSAVGRGRPASYLWDLGDGG-WLEGPEVTHAYNSTGDFTVRVAGWNEVSRS 1536
Score = 46.2 bits (108), Expect = 5e-04
Identities = 73/328 (22%), Positives = 126/328 (38%), Gaps = 46/328 (14%)
Query: 471 VIHHFPSIPSYNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTVFATDTDITFTAVT 530
V H + S + V +V S+AW ++TV +++ + V + TV + ++F+
Sbjct: 1513 VTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVVPLNGSVSFSTSL 1572
Query: 531 KETIPLEFEWYFGE-------DPPVRTTSRSIKKRLSIPQWYRVMVKASNRMSSVVSEPH 583
+ + + W + P + T RS+ + ++V A N + S
Sbjct: 1573 EAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGT-------FNIIVTAENEVGSAQDSIF 1625
Query: 584 VIRVQ----KKIVANRLTSPSSALVNASVAFECWINFGTDVAYLW----DFGDGTVSLGS 635
V +Q ++V P+ N +V + + GT+V+Y W D G G
Sbjct: 1626 VYVLQLIEGLQVVGGGRYFPT----NHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSGK 1681
Query: 636 SSSSHVYSREGEFTVEVLAFNNVSASTLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPV 695
S V G + V++ A N + ++ C V+ +G V P
Sbjct: 1682 GFSLTVL-EAGTYHVQLRATNMLGSA---------WADCTMDFVEPVGWLMVAA-SPNPA 1730
Query: 696 RLGVTFEAAVFCDISQGLSYTWNLMDSEGLPVSLPAAVDTHR-QTLILPSHTLEYGN--Y 752
+ + + G+ YTW+L EGL TH T L T+ GN
Sbjct: 1731 AVNTSVTLSAELAGGSGVVYTWSL--EEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLG 1788
Query: 753 TALAKVQIEGSVVYSNYCVGLEVRAQAP 780
+A A V+++ V S GL +RA P
Sbjct: 1789 SANATVEVDVQVPVS----GLSIRASEP 1812
Score = 44.7 bits (104), Expect = 0.001
Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 21/223 (9%)
Query: 471 VIHHFPSIPSYNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTVFATDTDITFTAVT 530
V+H + + Y ++ ++ + ++V + SV+V + V +TF
Sbjct: 1091 VMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVAGRPVTFYP-- 1148
Query: 531 KETIP----LEFEWYFGEDPPVRTTSRSIKKRLSIPQW-YRVMVKASNRMSSVVSEPHVI 585
+P + + W FG+ PV T S+ + Y V ++ +N +S ++ V
Sbjct: 1149 -HPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGAAAQADV- 1206
Query: 586 RVQKKIVANRLTSPSSALVNASVAFECWINFGTDVAYLWDFGDGTVSLGSSSS-SHVYSR 644
RV +++ + + A V + G ++ + +D GDGTV G ++ HVY R
Sbjct: 1207 RVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATVEHVYLR 1266
Query: 645 EGEFTVEVLAFNNVS--ASTLRQQLFIV---------CEPCQP 676
TV V A + A +L +F++ C P QP
Sbjct: 1267 AQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQP 1309
Score = 38.9 bits (89), Expect = 0.073
Identities = 50/199 (25%), Positives = 80/199 (40%), Gaps = 36/199 (18%)
Query: 565 YRVMVKASNRMSSVVSEPHVI--RVQKKIVANRLTSPSSALVNASVAFECWI--NFGTDV 620
+++ + ASN +S+V +V R+ + T P+ NA++A + + +V
Sbjct: 992 FKLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEV 1051
Query: 621 AYLWDFGDGTVSLG----------------------SSSSSHVYSREGEFTVEVLAFNNV 658
A+LW FGDG +L + H Y+ GE+ + VLA N
Sbjct: 1052 AFLWTFGDGEQALHQFQPPYNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASN-- 1109
Query: 659 SASTLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEAAVFCDISQGLSYTWN 718
+ L QQ+ + P + + G + R VTF G+ YTW+
Sbjct: 1110 AFENLTQQVPVSVRASLPSVAVGVSDGVLVAGRP------VTFYPHPL-PSPGGVLYTWD 1162
Query: 719 LMD-SEGLPVSLPAAVDTH 736
D S L S PAA T+
Sbjct: 1163 FGDGSPVLTQSQPAANHTY 1181
>gi|4505835 polycystin 2 [Homo sapiens]
Length = 968
Score = 98.6 bits (244), Expect = 8e-20
Identities = 111/470 (23%), Positives = 192/470 (40%), Gaps = 46/470 (9%)
Query: 2241 GEVEKVLAARQQARHLRWAHPPSKAQLRGTR----QRMRRESRTRAALRDISMDILMLLL 2296
G+ +V A + R LR L GTR RE ++ LR++ +L L++
Sbjct: 182 GQPPRVAWAERLVRGLRG--------LWGTRLMEESSTNREKYLKSVLRELVTYLLFLIV 233
Query: 2297 LLCVIYGRFSQDEYSLNQAIRKEF-----TRNARNCLGGLRNIADWWDWSLTTLLDGLYP 2351
L + YG S + Y + + + F ++ + L ++ D+W ++ +LLDGLY
Sbjct: 234 LCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYW 293
Query: 2352 GGTPSARVPGAQPGALGGKCYLIGSSVIRQLKVFPRHLCKPPRPFSALIED--SIPTCSP 2409
PS + + + L+G IRQL+V C P+ I++ + + S
Sbjct: 294 KMQPSNQTEADNRSFIFYENLLLGVPRIRQLRV-RNGSCSIPQDLRDEIKECYDVYSVSS 352
Query: 2410 EVGGPENP-----YLIDPENQNVTLNGPGGCG-----TREDCVLSLGRTRTEAHTALSRL 2459
E P P ++ E LNG G + L L RTR E ++ L
Sbjct: 353 EDRAPFGPRNGTAWIYTSEKD---LNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASL 409
Query: 2460 RASMWIDRSTRAVSVHFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSAL 2519
+ ++W+DR TRA + F++YN LF V L VE TG ++PS + + R +
Sbjct: 410 KKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTF 469
Query: 2520 QYHLMLPQLVFLALSLIHLCVQLYRMMDKGVLSYWRKPRNWLE-----LSVVGVSLTYYA 2574
+ L +++F ++ ++ + L Y+R N L+ LSVV + + Y
Sbjct: 470 DFFLAACEIIFCFFIFYYVVEEILEIRIH-KLHYFRSFWNCLDVVIVVLSVVAIGINIYR 528
Query: 2575 VSGHLVTLAGDVTNQFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQN 2634
S V L QF F + +A W + + + +F +K
Sbjct: 529 TSNVEVLL------QFLEDQ-NTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNR 581
Query: 2635 TMASCSSMMRHSLPSIFVAGLVGALMLAALSHLHRFLLSMWVLPPGTFTD 2684
TM+ S+ M +F ++ ++ A + L + V TF +
Sbjct: 582 TMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQE 631
>gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sapiens]
Length = 1114
Score = 79.3 bits (194), Expect = 5e-14
Identities = 43/118 (36%), Positives = 61/118 (51%), Gaps = 1/118 (0%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEK-PLFERNSRHTFILSAPAQL 1856
Y V + T A + V+I++ G+NG S T L FERN+ TF L
Sbjct: 776 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 835
Query: 1857 GLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTC 1914
G L K+R+WHD++G PGW +S+V VK+ + + F CWLS DG+ R+ C
Sbjct: 836 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTVRDFAC 893
Score = 63.9 bits (154), Expect = 2e-09
Identities = 42/118 (35%), Positives = 59/118 (50%), Gaps = 5/118 (4%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCG---DNGLSETKELSCPEKPLFERNSRHTFILSAPA 1854
++V I TG + A + V+I L G D G++ K S FER+S F +
Sbjct: 66 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKS-SKTNSDKFERDSIEIFTVET-L 123
Query: 1855 QLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVEREL 1912
LG L K+RL HD+ G +PGWF+ V V G+ FP WL+ DG + R+L
Sbjct: 124 DLGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLAKNEDDGSIIRDL 181
Score = 60.5 bits (145), Expect = 2e-08
Identities = 42/116 (36%), Positives = 59/116 (50%), Gaps = 3/116 (2%)
Query: 1797 LYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPL--FERNSRHTFILSAPA 1854
LY+V I TG A +KVYI + GD G + + L E FER + TFI+ A A
Sbjct: 350 LYSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEA-A 408
Query: 1855 QLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVER 1910
LG++ KI+L HD+ W++ V + + F WLS + DGR+ER
Sbjct: 409 DLGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKEDGRLER 464
Score = 54.7 bits (130), Expect = 1e-06
Identities = 33/123 (26%), Positives = 57/123 (46%), Gaps = 8/123 (6%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCP----EKPLFERNSRHTFILSAP 1853
Y + + T A + ++I++ G + + ++ C +K FER S FI+
Sbjct: 197 YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASRFIVELE 256
Query: 1854 AQLGLLRKIRLWHDSRGPSPGWFISHVMVKEL----HTGQGWFFPAQCWLSAGRHDGRVE 1909
++ KIR+ H++ G +PGW SHV ++ L + FP WL+ D +
Sbjct: 257 DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSEDDKKTI 316
Query: 1910 REL 1912
REL
Sbjct: 317 REL 319
Score = 52.4 bits (124), Expect = 6e-06
Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Query: 1797 LYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQL 1856
LY + + TG S +++ L G NG +E +L +K FER TFI+ +
Sbjct: 648 LYEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQLD-KKKARFEREQNDTFIMEI-LDI 705
Query: 1857 GLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLS 1900
K+R+ D G P WF+ +++K ++TG F WLS
Sbjct: 706 APFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 749
Score = 49.7 bits (117), Expect = 4e-05
Identities = 35/115 (30%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCG-DNGLSETKELSCPE-KPLFERNSRHTFILSAPAQ 1855
Y V + TG A S+ +I L G D+ S+ L P K F R S F + A
Sbjct: 518 YYVSVTTGKHKDAATDSRAFIFLIGEDDERSKRIWLDYPRGKRGFSRGSVEEFYV-AGLD 576
Query: 1856 LGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVER 1910
+G+++KI L HD P W + + + G + CWL+ R DG R
Sbjct: 577 VGIIKKIELGHDGASPESCWLVEELCLAVPTQGTKYMLNCNCWLAKDRGDGITSR 631
Score = 36.6 bits (83), Expect = 0.36
Identities = 18/53 (33%), Positives = 28/53 (52%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFIL 1850
Y V++ TG+ A + V++ + G NG + +EL + LFER S F L
Sbjct: 1045 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFL 1097
>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sapiens]
Length = 2211
Score = 79.3 bits (194), Expect = 5e-14
Identities = 43/118 (36%), Positives = 61/118 (51%), Gaps = 1/118 (0%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEK-PLFERNSRHTFILSAPAQL 1856
Y V + T A + V+I++ G+NG S T L FERN+ TF L
Sbjct: 1825 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 1884
Query: 1857 GLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTC 1914
G L K+R+WHD++G PGW +S+V VK+ + + F CWLS DG+ R+ C
Sbjct: 1885 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTVRDFAC 1942
Score = 74.3 bits (181), Expect = 2e-12
Identities = 43/115 (37%), Positives = 57/115 (49%), Gaps = 1/115 (0%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLG 1857
Y V++ TG+ A + V++ + G NG + +EL + LFER S F L +LG
Sbjct: 2094 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LELG 2152
Query: 1858 LLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVEREL 1912
LRK+RL HDS G GW + V V TG F WL R DG R+L
Sbjct: 2153 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWLDKKRGDGLTWRDL 2207
Score = 71.6 bits (174), Expect = 1e-11
Identities = 42/127 (33%), Positives = 71/127 (55%), Gaps = 4/127 (3%)
Query: 1792 LPGHQLYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILS 1851
+P Y V + TG A + V+I + G+ G + + L EK FE+ + FIL
Sbjct: 168 MPRGNKYEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRLE-NEKDNFEKGAEDRFILD 226
Query: 1852 APAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERE 1911
AP LG L KI + H+++G S GWF+S ++++++ + + FP WL+ DG+++R+
Sbjct: 227 AP-DLGQLMKINVGHNNKGGSAGWFLSQIVIEDIGNKRKYDFPLNRWLALDEDDGKIQRD 285
Query: 1912 LTCLQGG 1918
+ L GG
Sbjct: 286 I--LVGG 290
Score = 64.7 bits (156), Expect = 1e-09
Identities = 39/122 (31%), Positives = 62/122 (50%), Gaps = 3/122 (2%)
Query: 1793 PGHQLYAVVIDTGFRAPARLTSKVYIVLCGDN-GLSETKELSCPEKP-LFERNSRHTFIL 1850
P Y V + TG A + VY+ + G+ G + + L +K FE+ TF +
Sbjct: 1019 PERNTYEVQVVTGNVPKAGTDANVYLTIYGEEYGDTGERPLKKSDKSNKFEQGQTDTFTI 1078
Query: 1851 SAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVER 1910
A LG L KIR+ HD+ G GWF+ + + +++ ++FP Q WL+ DG++ R
Sbjct: 1079 YA-IDLGALTKIRIRHDNTGNRAGWFLDRIDITDMNNEITYYFPCQRWLAVEEDDGQLSR 1137
Query: 1911 EL 1912
EL
Sbjct: 1138 EL 1139
Score = 63.9 bits (154), Expect = 2e-09
Identities = 42/118 (35%), Positives = 59/118 (50%), Gaps = 5/118 (4%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCG---DNGLSETKELSCPEKPLFERNSRHTFILSAPA 1854
++V I TG + A + V+I L G D G++ K S FER+S F +
Sbjct: 1177 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKS-SKTNSDKFERDSIEIFTVET-L 1234
Query: 1855 QLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVEREL 1912
LG L K+RL HD+ G +PGWF+ V V G+ FP WL+ DG + R+L
Sbjct: 1235 DLGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLAKNEDDGSIIRDL 1292
Score = 60.8 bits (146), Expect = 2e-08
Identities = 37/118 (31%), Positives = 62/118 (52%), Gaps = 2/118 (1%)
Query: 1796 QLYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQ 1855
++Y VV TG A + V+I L G+NGLS +L+ K FE+ + F +
Sbjct: 43 RVYEVVTATGDVRGAGTDANVFITLFGENGLSPKLQLTSKSKSAFEKGNVDVFRVRT-NN 101
Query: 1856 LGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQ-GWFFPAQCWLSAGRHDGRVEREL 1912
+GL+ K+R+ HD+ G + W++ HV+V ++ ++F WLS D + R+L
Sbjct: 102 VGLIYKVRIEHDNTGLNASWYLDHVIVTDMKRPHLRYYFNCNNWLSKVEGDRQWCRDL 159
Score = 60.5 bits (145), Expect = 2e-08
Identities = 42/116 (36%), Positives = 59/116 (50%), Gaps = 3/116 (2%)
Query: 1797 LYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPL--FERNSRHTFILSAPA 1854
LY+V I TG A +KVYI + GD G + + L E FER + TFI+ A A
Sbjct: 1461 LYSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEA-A 1519
Query: 1855 QLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVER 1910
LG++ KI+L HD+ W++ V + + F WLS + DGR+ER
Sbjct: 1520 DLGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKEDGRLER 1575
Score = 59.7 bits (143), Expect = 4e-08
Identities = 38/118 (32%), Positives = 57/118 (48%), Gaps = 4/118 (3%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPE---KPLFERNSRHTFILSAPA 1854
Y + + TG + A S+VYI L GD + + L + K FER F L
Sbjct: 686 YHISLKTGDVSGASTDSRVYIKLYGDKSDTIKQVLLVSDNNLKDYFERGRVDEFTLET-L 744
Query: 1855 QLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVEREL 1912
+G + ++ + HDS G WF+ V ++ G+ + FPA WL + DGR+E EL
Sbjct: 745 NIGNINRLVIGHDSTGMHASWFLGSVQIRVPRQGKQYTFPANRWLDKNQADGRLEVEL 802
Score = 54.7 bits (130), Expect = 1e-06
Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 1/115 (0%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLG 1857
Y V + TG A SK+Y+V+ G G + ++ E +F+R F + L
Sbjct: 298 YIVTVFTGDVRGAGTKSKIYLVMYGARGNKNSGKIFL-EGGVFDRGRTDIFHIELAVLLS 356
Query: 1858 LLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVEREL 1912
L ++ + H + G + GWF V++ TG FP WL + DG +ER+L
Sbjct: 357 PLSRVSVGHGNVGVNRGWFCEKVVILCPFTGIQQTFPCSNWLDEKKADGLIERQL 411
Score = 54.7 bits (130), Expect = 1e-06
Identities = 33/123 (26%), Positives = 57/123 (46%), Gaps = 8/123 (6%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCP----EKPLFERNSRHTFILSAP 1853
Y + + T A + ++I++ G + + ++ C +K FER S FI+
Sbjct: 1308 YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASRFIVELE 1367
Query: 1854 AQLGLLRKIRLWHDSRGPSPGWFISHVMVKEL----HTGQGWFFPAQCWLSAGRHDGRVE 1909
++ KIR+ H++ G +PGW SHV ++ L + FP WL+ D +
Sbjct: 1368 DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSEDDKKTI 1427
Query: 1910 REL 1912
REL
Sbjct: 1428 REL 1430
Score = 53.9 bits (128), Expect = 2e-06
Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Query: 1794 GHQLYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKEL-SCPEKP-LFERNSRHTFILS 1851
G Y V + TG A + VY+ L GD G + + L +C LFE+ + F +
Sbjct: 551 GMARYHVTVCTGELEGAGTDANVYLCLFGDVGDTGERLLYNCRNNTDLFEKGNADEFTIE 610
Query: 1852 APAQLGLLRKIRLWHDSRGPSPGWFISHVMVKE--LHTGQGWFFPAQCWLSAGRHDGRVE 1909
+ + R++R+ HD +G GW++ V+V+E FP WL + DG++
Sbjct: 611 SVTMRNV-RRVRIRHDGKGSGSGWYLDRVLVREEGQPESDNVEFPCLRWLDKDKDDGQLV 669
Query: 1910 REL 1912
REL
Sbjct: 670 REL 672
Score = 53.1 bits (126), Expect = 4e-06
Identities = 34/88 (38%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLG 1857
Y V I TG A +++VY+ + G+ G +E LS K +FER S+ TF L A A +G
Sbjct: 816 YEVEIWTGDVGGAGTSARVYMQIYGEKGKTEVLFLSSRSK-VFERASKDTFQLEA-ADVG 873
Query: 1858 LLRKIRLWHDSRGPSPGWFISHVMVKEL 1885
+ K+RL H G P WF+ V ++ L
Sbjct: 874 EVYKLRLGHTGEGFGPSWFVDTVWLRHL 901
Score = 52.4 bits (124), Expect = 6e-06
Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Query: 1797 LYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQL 1856
LY + + TG S +++ L G NG +E +L +K FER TFI+ +
Sbjct: 1697 LYEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQLD-KKKARFEREQNDTFIMEI-LDI 1754
Query: 1857 GLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLS 1900
K+R+ D G P WF+ +++K ++TG F WLS
Sbjct: 1755 APFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 1798
Score = 48.5 bits (114), Expect = 9e-05
Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 2/104 (1%)
Query: 1810 ARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWHDSR 1869
A S ++I + G G ++ L+ P F+ F + P LG KIR+WHD R
Sbjct: 439 AGTNSPIFIQIYGQKGRTDEILLN-PNNKWFKPGIIEKFRIELP-DLGRFYKIRVWHDKR 496
Query: 1870 GPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELT 1913
GW + + + + F WL A D + RE+T
Sbjct: 497 SSGSGWHLERMTLMNTLNKDKYNFNCNRWLDANEDDNEIVREMT 540
>gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sapiens]
Length = 512
Score = 79.3 bits (194), Expect = 5e-14
Identities = 43/118 (36%), Positives = 61/118 (51%), Gaps = 1/118 (0%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEK-PLFERNSRHTFILSAPAQL 1856
Y V + T A + V+I++ G+NG S T L FERN+ TF L
Sbjct: 126 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 185
Query: 1857 GLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTC 1914
G L K+R+WHD++G PGW +S+V VK+ + + F CWLS DG+ R+ C
Sbjct: 186 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTVRDFAC 243
Score = 74.3 bits (181), Expect = 2e-12
Identities = 43/115 (37%), Positives = 57/115 (49%), Gaps = 1/115 (0%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLG 1857
Y V++ TG+ A + V++ + G NG + +EL + LFER S F L +LG
Sbjct: 395 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LELG 453
Query: 1858 LLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVEREL 1912
LRK+RL HDS G GW + V V TG F WL R DG R+L
Sbjct: 454 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWLDKKRGDGLTWRDL 508
Score = 48.9 bits (115), Expect = 7e-05
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Query: 1814 SKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWHDSRGPSP 1873
S +++ L G NG +E +L +K FER TFI+ + K+R+ D G P
Sbjct: 15 SNIFMTLYGINGSTEEMQLD-KKKARFEREQNDTFIMEI-LDIAPFTKMRIRIDGLGSRP 72
Query: 1874 GWFISHVMVKELHTGQGWFFPAQCWLS 1900
WF+ +++K ++TG F WLS
Sbjct: 73 EWFLERILLKNMNTGDLTMFYYGDWLS 99
>gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens]
Length = 613
Score = 78.2 bits (191), Expect = 1e-13
Identities = 94/414 (22%), Positives = 167/414 (40%), Gaps = 30/414 (7%)
Query: 2275 RRESRTRAALRDISMDILMLLLLLCVIYGRFSQDEYSLNQAIRKEFTRNA-----RNCLG 2329
R+E L+++ + + L+ L + +G + Y LN+ + F + R
Sbjct: 20 RKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFK 79
Query: 2330 GLRNIADWWDWSLTTLLDGLYPGGTPSAR--VPGAQPGALGGKCYLIGSSVIRQLKVFPR 2387
+R+I D+W + LL+GLY + + + + L+G +RQLKV
Sbjct: 80 SIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKV-RN 138
Query: 2388 HLCKPPRPFSALIEDSIPTCSPEVGGPENPYL-IDPENQNVTLN-------GPGGCGTRE 2439
+ CK F +L+ + + N L I+ E + T N G G
Sbjct: 139 NTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNTNSPWHWGFLGVYRNG 198
Query: 2440 DCVLSLGRTRTEAHTALSRLRASMWIDRSTRAVSVHFTLYNPPTQLFTSVSLRVEILPTG 2499
+ +L ++++E LR + WI R TR + + F+LYN LF + L E TG
Sbjct: 199 GYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATG 258
Query: 2500 SLVPSSLVESFSIFRSDSALQYHLMLPQLVFLALSLIHLCVQLYRMMDKGVLSYWRKPRN 2559
++ S S + R S Y + ++ F + L Q + + + +Y++ N
Sbjct: 259 GILTSWQFYSVKLLRYVSYYDYFIASCEITF-CIFLFVFTTQEVKKIKEFKSAYFKSIWN 317
Query: 2560 WLELSV-----VGVSL-TYYAVSGHLVTLAGDVTNQFHRGLCRAFMDLTLMASWNQRARW 2613
WLEL + V VS TYY V + L G + + + D +A W+
Sbjct: 318 WLELLLLLLCFVAVSFNTYYNV--QIFLLLGQLLKSTEK-----YSDFYFLACWHIYYNN 370
Query: 2614 LRGILLFLFTLKCVYLPGIQNTMASCSSMMRHSLPSIFVAGLVGALMLAALSHL 2667
+ I +F +K TM+ SS + + I ++ ++ A + L
Sbjct: 371 IIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQL 424
>gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens]
Length = 805
Score = 73.6 bits (179), Expect = 3e-12
Identities = 121/556 (21%), Positives = 211/556 (37%), Gaps = 52/556 (9%)
Query: 2276 RESRTRAALRDISMDILMLLLLLCVIYGRFSQDEYSLNQAIRKEFTRNARNC---LGGLR 2332
RE + LR++ + I+ L+ + + YG S Y + + + F + +
Sbjct: 93 RELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDTGVSFQAIS 152
Query: 2333 NIADWWDWSLTTLLDGLYPGGTPSARVPG-AQPGALGGKCYLIGSSVIRQLKVFPRHLCK 2391
++AD+WD++ LLD LY + + G + + L+G +RQLKV C
Sbjct: 153 SMADFWDFAQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKV-RNDSCV 211
Query: 2392 PPRPFSALIEDSIPTCSPEVG-----GPENPYLIDPENQNVTLNGPGGCGTREDC----- 2441
F I SP+ GP N +Q+ L G G
Sbjct: 212 VHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQD-ELGGFSHWGRLTSYSGGGY 270
Query: 2442 VLSLGRTRTEAHTALSRLRASMWIDRSTRAVSVHFTLYNPPTQLFTSVSLRVEILPTGSL 2501
L L +R + AL L+ +W+DR TR V + F++YN LF + L VE TG
Sbjct: 271 YLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGA 330
Query: 2502 VPSSLVESFSIFRSDSALQYHLMLPQLVFLALSLIHLCVQLYRMMDKGVLSYWRKPRNWL 2561
+PS + + + R S + ++ +++F ++ ++ + L Y N L
Sbjct: 331 IPSWQIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHR-LRYLSSIWNIL 389
Query: 2562 ELSVVGVSLTYYAVSGHLV------TLAGDVTNQFHRGLCRAFMDLTLMASWNQRARWLR 2615
+L V+ +S+ AV H+ L G + Q + D +A W + +
Sbjct: 390 DLVVILLSIV--AVGFHIFRTLEVNRLMGKLLQQ-----PNTYADFEFLAFWQTQYNNMN 442
Query: 2616 GILLFLFTLKCVYLPGIQNTMASCSSMMRHSLPSIFVAGLVGALMLAALSHLHRFLLSMW 2675
+ LF +K TM SS + I ++ ++ A + L L
Sbjct: 443 AVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQ 502
Query: 2676 VLPPGTFTDA----FPGLLFHFPRRSQKDCLLGLSKSDQRAMACYFGILLIVSATLCFGM 2731
V TF F +L F + + +++ YF + + F +
Sbjct: 503 VENFSTFIKCIFTQFRIILGDFDYNA-------IDNANRILGPAYFVTYVFF---VFFVL 552
Query: 2732 LRGFLMTLPQ-----KRKSFQSKSFVRLKDVTAYMWEKVLTFLRLETPKLEEAEMV---E 2783
L FL + K + K ++L D+ + K L LRL ++ + + V
Sbjct: 553 LNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGG 612
Query: 2784 NHNYYLDEFANLLDEL 2799
++F N L EL
Sbjct: 613 EQEIQFEDFTNTLREL 628
>gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens]
Length = 1029
Score = 61.6 bits (148), Expect = 1e-08
Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 2/117 (1%)
Query: 1797 LYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPL-FERNSRHTFILSAPAQ 1855
+Y V + TG A + VYI + G+ G + +++L + F R TF L A
Sbjct: 42 IYEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VH 100
Query: 1856 LGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVEREL 1912
LG L KI + HD GP GWF+ V++K+ T + F WL G D ++ REL
Sbjct: 101 LGDLCKIVIGHDGLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLDQGEDDCKIVREL 157
Score = 35.8 bits (81), Expect = 0.62
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 2/100 (2%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPL-FERNSRHTFILSAPAQL 1856
Y V + TG A S+V++ L G+ G S ++L + F+R F ++A L
Sbjct: 636 YQVDVYTGQLKHAETESEVFLCLFGERGDSGLRQLYKSNMQVKFQRGQIDKFQVAA-VSL 694
Query: 1857 GLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQ 1896
G L+K+ L ++ S W+ V+V+E T F Q
Sbjct: 695 GKLQKVLLRCEASDKSQYWYCEQVIVREPGTTSESIFTCQ 734
>gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo
sapiens]
Length = 1029
Score = 61.6 bits (148), Expect = 1e-08
Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 2/117 (1%)
Query: 1797 LYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPL-FERNSRHTFILSAPAQ 1855
+Y V + TG A + VYI + G+ G + +++L + F R TF L A
Sbjct: 42 IYEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VH 100
Query: 1856 LGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVEREL 1912
LG L KI + HD GP GWF+ V++K+ T + F WL G D ++ REL
Sbjct: 101 LGDLCKIVIGHDGLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLDQGEDDCKIVREL 157
Score = 35.8 bits (81), Expect = 0.62
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 2/100 (2%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPL-FERNSRHTFILSAPAQL 1856
Y V + TG A S+V++ L G+ G S ++L + F+R F ++A L
Sbjct: 636 YQVDVYTGQLKHAETESEVFLCLFGERGDSGLRQLYKSNMQVKFQRGQIDKFQVAA-VSL 694
Query: 1857 GLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQ 1896
G L+K+ L ++ S W+ V+V+E T F Q
Sbjct: 695 GKLQKVLLRCEASDKSQYWYCEQVIVREPGTTSESIFTCQ 734
>gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo
sapiens]
Length = 1029
Score = 61.6 bits (148), Expect = 1e-08
Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 2/117 (1%)
Query: 1797 LYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPL-FERNSRHTFILSAPAQ 1855
+Y V + TG A + VYI + G+ G + +++L + F R TF L A
Sbjct: 42 IYEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VH 100
Query: 1856 LGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVEREL 1912
LG L KI + HD GP GWF+ V++K+ T + F WL G D ++ REL
Sbjct: 101 LGDLCKIVIGHDGLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLDQGEDDCKIVREL 157
Score = 35.8 bits (81), Expect = 0.62
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 2/100 (2%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPL-FERNSRHTFILSAPAQL 1856
Y V + TG A S+V++ L G+ G S ++L + F+R F ++A L
Sbjct: 636 YQVDVYTGQLKHAETESEVFLCLFGERGDSGLRQLYKSNMQVKFQRGQIDKFQVAA-VSL 694
Query: 1857 GLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQ 1896
G L+K+ L ++ S W+ V+V+E T F Q
Sbjct: 695 GKLQKVLLRCEASDKSQYWYCEQVIVREPGTTSESIFTCQ 734
>gi|44889475 RAB6 interacting protein 1 [Homo sapiens]
Length = 1287
Score = 47.0 bits (110), Expect = 3e-04
Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Query: 1820 LCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISH 1879
+C L ET+ + P L TF LG L +++ HD+ G W + +
Sbjct: 977 ICISGELGETQIMQIPRNVL-----EMTFECQ---NLGKLTTVQIGHDNSGLYAKWLVEY 1028
Query: 1880 VMVKELHTGQGWFFPAQCWLSAGRHDGRVEREL 1912
VMV+ TG + FP WL G DG +ER L
Sbjct: 1029 VMVRNEITGHTYKFPCGRWLGKGMDDGSLERIL 1061
>gi|122891862 DENN/MADD domain containing 5B [Homo sapiens]
Length = 1274
Score = 45.1 bits (105), Expect = 0.001
Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 10/114 (8%)
Query: 1799 AVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGL 1858
+V+I + A +TS +I + G+ L +T + P+ L TF LG
Sbjct: 940 SVIIPIKKLSNAIITSNPWICVSGE--LGDTGVMQIPKNLL-----EMTFECQ---NLGK 989
Query: 1859 LRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVEREL 1912
L +++ HD+ G W + VMV+ TG + FP WL G DG +ER L
Sbjct: 990 LTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGIDDGSLERIL 1043
>gi|66529203 hypothetical protein LOC57714 [Homo sapiens]
Length = 1063
Score = 43.9 bits (102), Expect = 0.002
Identities = 50/171 (29%), Positives = 67/171 (39%), Gaps = 22/171 (12%)
Query: 961 GAISESSQLNLLPTEPGTADPDATTTPFSREPSPVTL--GQPATSAPRGTPTEPMTGVYW 1018
G S SS+L LP P A P T + P L Q S P G P++P G
Sbjct: 99 GNKSASSELASLPLSP--ASPCHLTLLSNPWPQDTALPHSQAQQSGPTGQPSQP-PGTAT 155
Query: 1019 IPPAGDSAVLGEAPEEGSLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDIQ 1078
P GD L E G L+ + + TG +S P D +A
Sbjct: 156 TPLEGDG--LSAPTEVGDSPLQAQALGEAGVATGSEAQSSPQFQDHTEGEDQDA------ 207
Query: 1079 EAIPSGGRQPAKDTSFPGSGPSLSAEE----SPGDGDNLVDPSLSAGRAEP 1125
+IPSGGR +++ G+GP SA E + L+ P G +EP
Sbjct: 208 -SIPSGGRGLSQE----GTGPPTSAGEGHSRTEDAAQELLLPESKGGSSEP 253
>gi|187960059 syndecan 3 [Homo sapiens]
Length = 442
Score = 42.0 bits (97), Expect = 0.009
Identities = 44/152 (28%), Positives = 55/152 (36%), Gaps = 6/152 (3%)
Query: 974 TEPGTADPDATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIPPAGDSAVLGEAPE 1033
T P P T E L ATS PR P T IP + AP
Sbjct: 225 TTPEAPSPPTTAAVLDTEAPTPRLVSTATSRPRALPRPATTQEPDIPERSTLPLGTTAP- 283
Query: 1034 EGSLDLEPGPQSKGSLMTGRSERSQPTH---SPDPHLSDFEAYYSDIQEAIPSGGRQPAK 1090
G ++ P + L T R E P S D L + E D + + G AK
Sbjct: 284 -GPTEVAQTPTPETFLTTIRDEPEVPVSGGPSGDFELPEEETTQPDTANEVVAVGGAAAK 342
Query: 1091 DTSFPGSGPSLSAEESPGDGDNLVDPSLSAGR 1122
+S PG+ P A PG DN +D SA +
Sbjct: 343 ASSPPGTLPK-GARPGPGLLDNAIDSGSSAAQ 373
>gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens]
Length = 674
Score = 40.8 bits (94), Expect = 0.019
Identities = 26/103 (25%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLG 1857
Y V + TG + A +Y+ L G G SE L P FER + ++ ++ +LG
Sbjct: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Query: 1858 LLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLS 1900
++ +R+ + W++ ++ +K H G FP W++
Sbjct: 64 EIQLVRIEKRKYWLNDDWYLKYITLKTPH-GDYIEFPCYRWIT 105
>gi|215820635 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 39.7 bits (91), Expect = 0.043
Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 11/90 (12%)
Query: 976 PGTADPDATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIPPAGDSAVLGEAPEEG 1035
P A D TPF R S TL + +P+G P+ P T +Y P A G
Sbjct: 85 PRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDA-----------YG 133
Query: 1036 SLDLEPGPQSKGSLMTGRSERSQPTHSPDP 1065
SLD P+ + G S P+ P P
Sbjct: 134 SLDRATSPRPRAFDGAGSSLGRAPSPRPGP 163
>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 39.7 bits (91), Expect = 0.043
Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 11/90 (12%)
Query: 976 PGTADPDATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIPPAGDSAVLGEAPEEG 1035
P A D TPF R S TL + +P+G P+ P T +Y P A G
Sbjct: 85 PRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDA-----------YG 133
Query: 1036 SLDLEPGPQSKGSLMTGRSERSQPTHSPDP 1065
SLD P+ + G S P+ P P
Sbjct: 134 SLDRATSPRPRAFDGAGSSLGRAPSPRPGP 163
>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 39.7 bits (91), Expect = 0.043
Identities = 40/152 (26%), Positives = 56/152 (36%), Gaps = 47/152 (30%)
Query: 987 PFSREPSPVTLGQPATSAPR-----------------------------GTPTEPMTGVY 1017
P P+PV + QP AP+ TPT P TG
Sbjct: 155 PTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGG 214
Query: 1018 WIPPAGDSAVLGEAPEEGSLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDI 1077
P A GE P+ + + P +S+G+++ R P HSP S+
Sbjct: 215 LEPQAN-----GETPQVAVI-VRPDDRSQGAIIADRPGLPGPEHSP-----------SES 257
Query: 1078 QEAIPSGGRQPAKDTSFPGSGPSLSAEESPGD 1109
Q + PS P+ PGS P+L+ PGD
Sbjct: 258 QPSSPSPTPSPSPVLE-PGSEPNLAVLSIPGD 288
>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
isoform 2 [Homo sapiens]
Length = 1512
Score = 39.7 bits (91), Expect = 0.043
Identities = 40/152 (26%), Positives = 56/152 (36%), Gaps = 47/152 (30%)
Query: 987 PFSREPSPVTLGQPATSAPR-----------------------------GTPTEPMTGVY 1017
P P+PV + QP AP+ TPT P TG
Sbjct: 68 PTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGG 127
Query: 1018 WIPPAGDSAVLGEAPEEGSLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDI 1077
P A GE P+ + + P +S+G+++ R P HSP S+
Sbjct: 128 LEPQAN-----GETPQVAVI-VRPDDRSQGAIIADRPGLPGPEHSP-----------SES 170
Query: 1078 QEAIPSGGRQPAKDTSFPGSGPSLSAEESPGD 1109
Q + PS P+ PGS P+L+ PGD
Sbjct: 171 QPSSPSPTPSPSPVLE-PGSEPNLAVLSIPGD 201
>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 39.7 bits (91), Expect = 0.043
Identities = 40/152 (26%), Positives = 56/152 (36%), Gaps = 47/152 (30%)
Query: 987 PFSREPSPVTLGQPATSAPR-----------------------------GTPTEPMTGVY 1017
P P+PV + QP AP+ TPT P TG
Sbjct: 155 PTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGG 214
Query: 1018 WIPPAGDSAVLGEAPEEGSLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDI 1077
P A GE P+ + + P +S+G+++ R P HSP S+
Sbjct: 215 LEPQAN-----GETPQVAVI-VRPDDRSQGAIIADRPGLPGPEHSP-----------SES 257
Query: 1078 QEAIPSGGRQPAKDTSFPGSGPSLSAEESPGD 1109
Q + PS P+ PGS P+L+ PGD
Sbjct: 258 QPSSPSPTPSPSPVLE-PGSEPNLAVLSIPGD 288
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 39.7 bits (91), Expect = 0.043
Identities = 42/159 (26%), Positives = 53/159 (33%), Gaps = 22/159 (13%)
Query: 976 PGTADPD-ATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIPPAGDSAVLGEAPEE 1034
P T P A T P + PSP G PAT +P+G PT P PP +P+
Sbjct: 954 PATPSPKWAPTPPAATPPSPK--GGPATPSPKGAPTPPAA----TPP---------SPKG 998
Query: 1035 GSLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDIQEAIPSGGRQPAKDTSF 1094
G P +T S + P +P P + S A P + T
Sbjct: 999 GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGA------STPPAATPPSPKGSPAATPL 1052
Query: 1095 PGSGPSLSAEESPGDGDNLVDPSLSAGRAEPVLMIDWPK 1133
P P+ A P PSL P PK
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK 1091
Score = 35.0 bits (79), Expect = 1.1
Identities = 44/155 (28%), Positives = 55/155 (35%), Gaps = 19/155 (12%)
Query: 977 GTADPD---ATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIPPAGDSAVLGEAPE 1033
G A P A TTP + PSP G PAT P+G PT P P L P
Sbjct: 1231 GLATPSPKGAPTTPAATPPSPK--GGPATPPPKGAPTPPAA-----TPPSLKGGLATPPH 1283
Query: 1034 EGSLD--LEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDIQEAIPSGG-RQPAK 1090
+G+ + + P KG T S P +P P + + P G PA
Sbjct: 1284 KGAPNPAVVTPPSPKGGPAT-----SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAV 1338
Query: 1091 DTSFPGSGPSLSAEESPGDGDNLVDPSLSAGRAEP 1125
P P+L A +P PS G P
Sbjct: 1339 TPPSPKGTPTLPA-TTPSSKGGPTTPSSKEGPTPP 1372
Score = 34.7 bits (78), Expect = 1.4
Identities = 43/174 (24%), Positives = 57/174 (32%), Gaps = 37/174 (21%)
Query: 973 PTEPGTADPDA----TTTPFSREPSPVTL------GQPATSAPRGTPTEPMTGVYWIPPA 1022
PT P P T P P+P + G PATS P+G PT P P
Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA-----TPP 1318
Query: 1023 GDSAVLGEAPEEGS----LDLEPGPQSKGSL-MTGRSERSQPT-----HSPDPHLSDFEA 1072
G P +G+ P P+ +L T S + PT P P
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP------- 1371
Query: 1073 YYSDIQEAIPSGGRQPAKDTSFPGSGPSLSAEESPGDGDNLVDPSLSAGRAEPV 1126
A PS PA P GP++ + + ++ S A PV
Sbjct: 1372 -----PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPV 1420
Score = 33.9 bits (76), Expect = 2.4
Identities = 42/162 (25%), Positives = 51/162 (31%), Gaps = 30/162 (18%)
Query: 977 GTADPD---ATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIPPAGDSAVLGEAPE 1033
G A P A T P + PSP G PAT +P+G P P P L P
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPK--GGPATPSPKGAPMPPAA-----TPPSPKGGLATPPH 1122
Query: 1034 EG--SLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDIQEAIPSGGRQPAKD 1091
+G + P KG L T + + T + P P GG
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP--------------PSPKGGLA---- 1164
Query: 1092 TSFPGSGPSLSAEESPGDGDNLVDPSLSAGRAEPVLMIDWPK 1133
T P P+ A P L PS P PK
Sbjct: 1165 TPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1206
Score = 32.7 bits (73), Expect = 5.3
Identities = 41/140 (29%), Positives = 52/140 (37%), Gaps = 30/140 (21%)
Query: 977 GTADPD---ATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIPPAGDSAVLGEAPE 1033
G A P A TTP + PSP G AT +P+G PT P PP+ P+
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPK--GGLATPSPKGAPTTPAA----TPPSPKGGPATPPPK 1261
Query: 1034 EGSLDLEPGPQS-KGSLMTGRSERSQPTH--SPDPHLSDFEAYYSDIQEAIPSGG--RQP 1088
P S KG L T P H +P+P + + P GG P
Sbjct: 1262 GAPTPPAATPPSLKGGLAT-------PPHKGAPNPAV---------VTPPSPKGGPATSP 1305
Query: 1089 AKDTSFPGSGPSLSAEESPG 1108
K P + S + SPG
Sbjct: 1306 PKGAPTPPAATPPSPKGSPG 1325
Score = 32.3 bits (72), Expect = 6.9
Identities = 37/161 (22%), Positives = 46/161 (28%), Gaps = 28/161 (17%)
Query: 973 PTEPGTADPDATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIPPAGDSAVLGEAP 1032
P+ G P A T P + + A + P TP P G+ PP G P
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156
Query: 1033 EEGSLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDIQEAIPSGGRQPAKDT 1092
P KG L T + + T + P P GG T
Sbjct: 1157 ----------PSPKGGLATPPPKGAPTTPAATP--------------PSPKGGLA----T 1188
Query: 1093 SFPGSGPSLSAEESPGDGDNLVDPSLSAGRAEPVLMIDWPK 1133
P P+ A P L PS P PK
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229
Score = 32.3 bits (72), Expect = 6.9
Identities = 33/155 (21%), Positives = 58/155 (37%), Gaps = 20/155 (12%)
Query: 973 PTEPGTADPDATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIPPAGDSAVLGEAP 1032
PT P P TP +P + G P T + + PT PPA + G
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT---------PPAATPSHKG--- 1380
Query: 1033 EEGSLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDIQEAIPSGGRQPAKDT 1092
G P P+ ++ + + + + P P LS +A + + G P+K
Sbjct: 1381 --GPAMTPPSPKRGPAIPSPKGDPTSPAVIP---LSPKKAPATPVTR---EGAATPSKGD 1432
Query: 1093 SFPGSGPSLSAEESPGDGDNLVDPSLSAGRAEPVL 1127
P + +S +++P P+ + + +P L
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467
Score = 32.3 bits (72), Expect = 6.9
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 2/45 (4%)
Query: 968 QLNLLPTEPGTADPDATTTPFSREPSPVTLGQPATSAPRGTPTEP 1012
+L + P + +A T P PSP PAT AP+GTPT P
Sbjct: 1598 ELLIPPAVTSPSPKEAPTPPAVTPPSPEK--GPATPAPKGTPTSP 1640
>gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]
Length = 845
Score = 39.3 bits (90), Expect = 0.056
Identities = 69/266 (25%), Positives = 96/266 (36%), Gaps = 44/266 (16%)
Query: 973 PTEPGTADPDATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIPPAGDSAVLGEAP 1032
P GT P +TT P + G TS+ GT P +G PP S G
Sbjct: 465 PEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPT-SSTPGGPPG 523
Query: 1033 EEGSLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDIQEAIPSGG--RQPAK 1090
E S +P + T + SQP P + ++ Q A PSGG + P
Sbjct: 524 AENSTSHQPATPGGDTAQTPKPGTSQPM---PPGVGTSTSH----QPATPSGGTAQTPEP 576
Query: 1091 DTSF---PGSGPSLSAEESPGDGDNLVDPSLSAGRAEPVLMIDWPKALLGRAVFQGYSSS 1147
TS P G S S + + G P AG ++P+ P + Q +
Sbjct: 577 GTSQPMPPSMGTSTSHQPATPGGGTAQTP--EAGTSQPM-----PPGMGTSTSHQPTTPG 629
Query: 1148 GITEQTV---TIKPYSLS----------SGETYVLQVSVASKHGLLGKAQLYLTVNPAPR 1194
G T QT T +P LS S + V +A+ G+LG L +
Sbjct: 630 GGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLG---- 685
Query: 1195 DMACQVQPHHGLEAHTVFSVFCMSGK 1220
+A V H+G + C SGK
Sbjct: 686 -LAVLVHKHYGPR------LKCCSGK 704
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 117,536,642
Number of Sequences: 37866
Number of extensions: 5758655
Number of successful extensions: 17404
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 139
Number of HSP's that attempted gapping in prelim test: 16424
Number of HSP's gapped (non-prelim): 988
length of query: 2849
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2729
effective length of database: 13,703,598
effective search space: 37397118942
effective search space used: 37397118942
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.