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Search of human proteins with 197304746
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197304746 RUN domain containing 3B isoform c [Homo sapiens]
(407 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197304746 RUN domain containing 3B isoform c [Homo sapiens] 802 0.0
gi|197304744 RUN domain containing 3B isoform b [Homo sapiens] 779 0.0
gi|19923090 RUN domain containing 3B isoform a [Homo sapiens] 768 0.0
gi|221307578 RUN domain containing 3A isoform 1 [Homo sapiens] 401 e-112
gi|221307580 RUN domain containing 3A isoform 3 [Homo sapiens] 368 e-102
gi|5730015 RUN domain containing 3A isoform 2 [Homo sapiens] 362 e-100
gi|195220720 RUN and FYVE domain containing 3 isoform 3 [Homo sa... 125 7e-29
gi|7662352 RUN and FYVE domain containing 3 isoform 2 [Homo sapi... 120 3e-27
gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo sap... 120 3e-27
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 114 1e-25
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 112 8e-25
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 106 3e-23
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 106 3e-23
gi|109240552 RUN and FYVE domain-containing 2 isoform b [Homo sa... 82 7e-16
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 67 4e-11
gi|116292170 RUN domain containing 2A [Homo sapiens] 62 7e-10
gi|221139728 pleckstrin homology domain containing, family M (wi... 47 4e-05
gi|122891862 DENN/MADD domain containing 5B [Homo sapiens] 47 4e-05
gi|44889475 RAB6 interacting protein 1 [Homo sapiens] 45 2e-04
gi|40538728 pleckstrin homology domain containing, family M (wit... 43 6e-04
gi|31982906 cingulin-like 1 [Homo sapiens] 37 0.032
gi|117414154 sodium channel associated protein 2 isoform b [Homo... 36 0.055
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 36 0.055
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens] 36 0.055
gi|16306548 seryl-tRNA synthetase [Homo sapiens] 36 0.072
gi|5032281 dystrophin Dp427c isoform [Homo sapiens] 35 0.16
gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens] 35 0.16
gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens] 35 0.16
gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens] 35 0.16
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens] 35 0.16
>gi|197304746 RUN domain containing 3B isoform c [Homo sapiens]
Length = 407
Score = 802 bits (2071), Expect = 0.0
Identities = 407/407 (100%), Positives = 407/407 (100%)
Query: 1 MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS 60
MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS
Sbjct: 1 MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS 60
Query: 61 PEFNNFAAILEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSS 120
PEFNNFAAILEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSS
Sbjct: 61 PEFNNFAAILEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSS 120
Query: 121 SRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAI 180
SRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAI
Sbjct: 121 SRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAI 180
Query: 181 DFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPP 240
DFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPP
Sbjct: 181 DFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPP 240
Query: 241 FLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLA 300
FLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLA
Sbjct: 241 FLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLA 300
Query: 301 HKLEKEQLEYIIVELQDQLKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEG 360
HKLEKEQLEYIIVELQDQLKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEG
Sbjct: 301 HKLEKEQLEYIIVELQDQLKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEG 360
Query: 361 KEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS 407
KEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS
Sbjct: 361 KEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS 407
>gi|197304744 RUN domain containing 3B isoform b [Homo sapiens]
Length = 456
Score = 779 bits (2011), Expect = 0.0
Identities = 407/456 (89%), Positives = 407/456 (89%), Gaps = 49/456 (10%)
Query: 1 MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS 60
MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS
Sbjct: 1 MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS 60
Query: 61 PEFNNFAAILEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSS 120
PEFNNFAAILEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSS
Sbjct: 61 PEFNNFAAILEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSS 120
Query: 121 SRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAI 180
SRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAI
Sbjct: 121 SRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAI 180
Query: 181 DFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPP 240
DFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPP
Sbjct: 181 DFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPP 240
Query: 241 FLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLA 300
FLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLA
Sbjct: 241 FLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLA 300
Query: 301 HKLEKEQLEYIIVELQDQL----------------------------------------- 319
HKLEKEQLEYIIVELQDQL
Sbjct: 301 HKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPSPGALDVNAVALDTLLYR 360
Query: 320 --------KSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLC 371
KSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLC
Sbjct: 361 KHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLC 420
Query: 372 GSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS 407
GSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS
Sbjct: 421 GSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS 456
>gi|19923090 RUN domain containing 3B isoform a [Homo sapiens]
Length = 473
Score = 768 bits (1983), Expect = 0.0
Identities = 407/473 (86%), Positives = 407/473 (86%), Gaps = 66/473 (13%)
Query: 1 MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS 60
MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS
Sbjct: 1 MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS 60
Query: 61 PEFNNFAAILEQILSHRLK-----------------GQVTWFGYESPRSFWDYIRVACRK 103
PEFNNFAAILEQILSHRLK GQVTWFGYESPRSFWDYIRVACRK
Sbjct: 61 PEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRK 120
Query: 104 VSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVL 163
VSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVL
Sbjct: 121 VSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVL 180
Query: 164 GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRT 223
GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRT
Sbjct: 181 GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRT 240
Query: 224 LGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSES 283
LGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSES
Sbjct: 241 LGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSES 300
Query: 284 VSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQL------------------------ 319
VSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQL
Sbjct: 301 VSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPS 360
Query: 320 -------------------------KSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTL 354
KSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTL
Sbjct: 361 PGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTL 420
Query: 355 NVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS 407
NVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS
Sbjct: 421 NVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS 473
>gi|221307578 RUN domain containing 3A isoform 1 [Homo sapiens]
Length = 446
Score = 401 bits (1031), Expect = e-112
Identities = 225/441 (51%), Positives = 290/441 (65%), Gaps = 58/441 (13%)
Query: 18 GGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHR 77
G K S+RN AVER+NLITVCRFSVKTL+++ E IDDSS EF NFAAILEQILSHR
Sbjct: 13 GLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHR 72
Query: 78 LK-----GQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVA 132
K G V+WF + R FWDYIR+AC KV NC+ SIENMEN+S++RAKGRAWIRVA
Sbjct: 73 FKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVA 132
Query: 133 LMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLD 192
LMEK +SEYI+TALRD +TTRRFY+ GAI+L +EA +L GML+GL+AIDFSFCLKGE LD
Sbjct: 133 LMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAIDFSFCLKGEVLD 192
Query: 193 GSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFNKC 252
G P VIDYTPYLK+ QS D + +DEEE + SS SE ++PE+ P + DE+SW++K
Sbjct: 193 GKTPVVIDYTPYLKFTQSYDYL-TDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYSKW 251
Query: 253 KRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYII 312
+++QK+++ QKGYLEEL+RLRE+QL + ++N+ L ++E++ ++ EK +LE +I
Sbjct: 252 HKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVI 311
Query: 313 VELQDQL----------------------------------------------KSYQSLD 326
+ELQ+QL S+ S +
Sbjct: 312 LELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSKLYRRHSFMSTE 371
Query: 327 QLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSL 386
LSAE SLS S + G+G +D GK+ TPS+LGLCGSL S+ S KSL S
Sbjct: 372 PLSAEASLSSDS-----QRLGEGTRDEEPWGPIGKDPTPSMLGLCGSLASIPSCKSLASF 426
Query: 387 KSNDYLASPTTEMTSPGLTPS 407
KSN+ L S + E SP L+PS
Sbjct: 427 KSNECLVSDSPE-GSPALSPS 446
>gi|221307580 RUN domain containing 3A isoform 3 [Homo sapiens]
Length = 400
Score = 368 bits (944), Expect = e-102
Identities = 183/302 (60%), Positives = 237/302 (78%), Gaps = 1/302 (0%)
Query: 18 GGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHR 77
G K S+RN AVER+NLITVCRFSVKTL+++ E IDDSS EF NFAAILEQILSHR
Sbjct: 13 GLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHR 72
Query: 78 LKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKH 137
KG V+WF + R FWDYIR+AC KV NC+ SIENMEN+S++RAKGRAWIRVALMEK
Sbjct: 73 FKGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKR 132
Query: 138 LSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPA 197
+SEYI+TALRD +TTRRFY+ GAI+L +EA +L GML+GL+AIDFSFCLKGE LDG P
Sbjct: 133 MSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAIDFSFCLKGEVLDGKTPV 192
Query: 198 VIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQ 257
VIDYTPYLK+ QS D + +DEEE + SS SE ++PE+ P + DE+SW++K +++Q
Sbjct: 193 VIDYTPYLKFTQSYDYL-TDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYSKWHKMEQ 251
Query: 258 KYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQD 317
K+++ QKGYLEEL+RLRE+QL + ++N+ L ++E++ ++ EK +LE +I+ELQ+
Sbjct: 252 KFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVILELQE 311
Query: 318 QL 319
QL
Sbjct: 312 QL 313
>gi|5730015 RUN domain containing 3A isoform 2 [Homo sapiens]
Length = 405
Score = 362 bits (928), Expect = e-100
Identities = 183/307 (59%), Positives = 237/307 (77%), Gaps = 6/307 (1%)
Query: 18 GGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHR 77
G K S+RN AVER+NLITVCRFSVKTL+++ E IDDSS EF NFAAILEQILSHR
Sbjct: 13 GLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHR 72
Query: 78 LK-----GQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVA 132
K G V+WF + R FWDYIR+AC KV NC+ SIENMEN+S++RAKGRAWIRVA
Sbjct: 73 FKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVA 132
Query: 133 LMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLD 192
LMEK +SEYI+TALRD +TTRRFY+ GAI+L +EA +L GML+GL+AIDFSFCLKGE LD
Sbjct: 133 LMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAIDFSFCLKGEVLD 192
Query: 193 GSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFNKC 252
G P VIDYTPYLK+ QS D + +DEEE + SS SE ++PE+ P + DE+SW++K
Sbjct: 193 GKTPVVIDYTPYLKFTQSYDYL-TDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYSKW 251
Query: 253 KRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYII 312
+++QK+++ QKGYLEEL+RLRE+QL + ++N+ L ++E++ ++ EK +LE +I
Sbjct: 252 HKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVI 311
Query: 313 VELQDQL 319
+ELQ+QL
Sbjct: 312 LELQEQL 318
>gi|195220720 RUN and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 125 bits (314), Expect = 7e-29
Identities = 106/378 (28%), Positives = 175/378 (46%), Gaps = 46/378 (12%)
Query: 14 GGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCF--ETIDDSSPEFNNFAAILE 71
GGG G K A ER NL+ + + S+K LI+ + T+D F ++E
Sbjct: 110 GGGSSGSGKHHPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVME 169
Query: 72 QILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQ--NCICSIENMENVSSSRAKGRAWI 129
L H LK + T+ G +SFW + + + V + S++++ + + +GRAW+
Sbjct: 170 HCLKHGLKAKKTFLGQN--KSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWL 227
Query: 130 RVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGE 189
R+ALM+K LSEY+ + + FYE A+++ EE ++AG+L+GLN ID +FC+KGE
Sbjct: 228 RLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANFCMKGE 287
Query: 190 GLDGSFPAVIDYTPYLKYIQSSDSISSD------------EEELR-----TLGSSGSESS 232
LD S VID++ YLK SS D EEL T+ + ++
Sbjct: 288 DLD-SQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVD 346
Query: 233 TPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRL--RENQLSESVSQNKIL 290
E + N+ ++++ + E+ Y+ E R ++++ +E + ++
Sbjct: 347 ALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKGPKQDRTAEGQALSEAR 406
Query: 291 LQRIEDSDLAHKLEKE----------------QLEYIIVELQDQLKSY-QSLDQLSA--- 330
E++ L +EKE LE + E QD L S Q LD L A
Sbjct: 407 KHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKH 466
Query: 331 EVSLSQTSLDPGQSQEGD 348
E++ S D G Q+ +
Sbjct: 467 ELAFKLQSSDLGVKQKSE 484
>gi|7662352 RUN and FYVE domain containing 3 isoform 2 [Homo
sapiens]
Length = 469
Score = 120 bits (300), Expect = 3e-27
Identities = 101/362 (27%), Positives = 170/362 (46%), Gaps = 46/362 (12%)
Query: 30 AVERRNLITVCRFSVKTLIDRSCF--ETIDDSSPEFNNFAAILEQILSHRLKGQVTWFGY 87
A ER NL+ + + S+K LI+ + T+D F ++E L H LK + T+ G
Sbjct: 66 ANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQ 125
Query: 88 ESPRSFWDYIRVACRKVSQ--NCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTA 145
+SFW + + + V + S++++ + + +GRAW+R+ALM+K LSEY+
Sbjct: 126 N--KSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKAL 183
Query: 146 LRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYL 205
+ + FYE A+++ EE ++AG+L+GLN ID +FC+KGE LD S VID++ YL
Sbjct: 184 INKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANFCMKGEDLD-SQVGVIDFSMYL 242
Query: 206 KYIQSSDSISSD------------EEELR-----TLGSSGSESSTPENVGPPFLMDENSW 248
K SS D EEL T+ + ++ E +
Sbjct: 243 KDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVA 302
Query: 249 FNKCKRVKQKYQLTLEQKGYLEELLRL--RENQLSESVSQNKILLQRIEDSDLAHKLEKE 306
N+ ++++ + E+ Y+ E R ++++ +E + ++ E++ L +EKE
Sbjct: 303 NNRIITLQEEMERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKE 362
Query: 307 ----------------QLEYIIVELQDQLKSY-QSLDQLSA---EVSLSQTSLDPGQSQE 346
LE + E QD L S Q LD L A E++ S D G Q+
Sbjct: 363 LEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQSSDLGVKQK 422
Query: 347 GD 348
+
Sbjct: 423 SE 424
>gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 620
Score = 120 bits (300), Expect = 3e-27
Identities = 101/362 (27%), Positives = 170/362 (46%), Gaps = 46/362 (12%)
Query: 30 AVERRNLITVCRFSVKTLIDRSCF--ETIDDSSPEFNNFAAILEQILSHRLKGQVTWFGY 87
A ER NL+ + + S+K LI+ + T+D F ++E L H LK + T+ G
Sbjct: 66 ANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQ 125
Query: 88 ESPRSFWDYIRVACRKVSQ--NCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTA 145
+SFW + + + V + S++++ + + +GRAW+R+ALM+K LSEY+
Sbjct: 126 N--KSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKAL 183
Query: 146 LRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYL 205
+ + FYE A+++ EE ++AG+L+GLN ID +FC+KGE LD S VID++ YL
Sbjct: 184 INKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANFCMKGEDLD-SQVGVIDFSMYL 242
Query: 206 KYIQSSDSISSD------------EEELR-----TLGSSGSESSTPENVGPPFLMDENSW 248
K SS D EEL T+ + ++ E +
Sbjct: 243 KDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVA 302
Query: 249 FNKCKRVKQKYQLTLEQKGYLEELLRL--RENQLSESVSQNKILLQRIEDSDLAHKLEKE 306
N+ ++++ + E+ Y+ E R ++++ +E + ++ E++ L +EKE
Sbjct: 303 NNRIITLQEEMERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKE 362
Query: 307 ----------------QLEYIIVELQDQLKSY-QSLDQLSA---EVSLSQTSLDPGQSQE 346
LE + E QD L S Q LD L A E++ S D G Q+
Sbjct: 363 LEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQSSDLGVKQK 422
Query: 347 GD 348
+
Sbjct: 423 SE 424
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 114 bits (286), Expect = 1e-25
Identities = 91/336 (27%), Positives = 162/336 (48%), Gaps = 21/336 (6%)
Query: 2 ASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDR--SCFETIDDS 59
A R+ GL G G G G ++ S ER NL+ + + S+K L+ S ++D
Sbjct: 84 ALRAAAGLGG--GDSGDGTARAASKCQMMEERANLMHMMKLSIKVLLQSALSLGRSLDAD 141
Query: 60 SPEFNNFAAILEQILSHRLKGQVTWFGYESPRSFW---DYIRVACRKVSQNCICSIENME 116
F ++E L H LK + ++ G +SF+ + + C + S + S+ N+
Sbjct: 142 HAPLQQFFVVMEHCLKHGLKVKKSFIGQN--KSFFGPLELVEKLCPEAS-DIATSVRNLP 198
Query: 117 NVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLG 176
+ ++ +GRAW+ +ALM+K L++Y+ + + FYE A+++ EE ++ G+L+G
Sbjct: 199 ELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKHLLSEFYEPEALMMEEEGMVIVGLLVG 258
Query: 177 LNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPEN 236
LN +D + CLKGE LD S VID++ YLK +Q D E L +
Sbjct: 259 LNVLDANLCLKGEDLD-SQVGVIDFSLYLKDVQDLDGGKEHERITDVLDQKNYVEELNRH 317
Query: 237 VGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIED 296
+ + D + + ++ K Q E + + L+E Q + QN+++ +R E
Sbjct: 318 LSCT-VGDLQTKIDGLEKTNSKLQ--EELSAATDRICSLQEEQ-QQLREQNELIRERSEK 373
Query: 297 SDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAEV 332
S K + + VEL+ ++ Q LD++ ++V
Sbjct: 374 SVEITKQDTK------VELETYKQTRQGLDEMYSDV 403
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 112 bits (279), Expect = 8e-25
Identities = 85/336 (25%), Positives = 167/336 (49%), Gaps = 19/336 (5%)
Query: 2 ASRSLGGLSGIRGGGGGG-GKKSLSARN-AAVERRNLITVCRFSVKTLIDR--SCFETID 57
AS+ L + GG G ++SL+ ++ AVER NL+ + + S+K LI+ S T+D
Sbjct: 13 ASQVLAWVPDAEGGRRGMLTRRSLATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLD 72
Query: 58 DSSPEFNNFAAILEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKV--SQNCICSIENM 115
P F ++E L H LK + ++ Y ++ W + + + ++ S+ ++
Sbjct: 73 SDYPPLQQFFVVMEHCLKHGLKVRKSFLSYN--KTIWGPLELVEKLYPEAEEIGASVRDL 130
Query: 116 ENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLL 175
+ + + RAW+R+ALM+K +++Y+ + FYE A+++ EE ++ G+L+
Sbjct: 131 PGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLV 190
Query: 176 GLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPE 235
GLN ID + C+KGE LD S VID++ YLK + + I + E ++ + + + + E
Sbjct: 191 GLNVIDANLCVKGEDLD-SQVGVIDFSMYLK---NEEDIGNKERNVQ-IAAILDQKNYVE 245
Query: 236 NVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIE 295
+ +S ++ +++ +E+ + + + + + S+NK++L + +
Sbjct: 246 ELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQ 305
Query: 296 DSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAE 331
K++ E ELQ S Q LD++ E
Sbjct: 306 QHLEVTKVDVE------TELQTYKHSRQGLDEMYNE 335
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 106 bits (265), Expect = 3e-23
Identities = 82/306 (26%), Positives = 150/306 (49%), Gaps = 19/306 (6%)
Query: 32 ERRNLITVCRFSVKTLIDR--SCFETIDDSSPEFNNFAAILEQILSHRLKGQVTWFGYES 89
ER NL+ + + S+K L+ S ++D F ++E L H LK + ++ G
Sbjct: 4 ERANLMHMMKLSIKVLLQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLKVKKSFIGQN- 62
Query: 90 PRSFW---DYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTAL 146
+SF+ + + C + S + S+ N+ + ++ +GRAW+ +ALM+K L++Y+ +
Sbjct: 63 -KSFFGPLELVEKLCPEAS-DIATSVRNLPELKTAVGRGRAWLYLALMQKKLADYLKVLI 120
Query: 147 RDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLK 206
+ FYE A+++ EE ++ G+L+GLN +D + CLKGE LD S VID++ YLK
Sbjct: 121 DNKHLLSEFYEPEALMMEEEGMVIVGLLVGLNVLDANLCLKGEDLD-SQVGVIDFSLYLK 179
Query: 207 YIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQK 266
+Q D E L ++ + D + + ++ K Q E
Sbjct: 180 DVQDLDGGKEHERITDVLDQKNYVEELNRHLSCT-VGDLQTKIDGLEKTNSKLQ--EELS 236
Query: 267 GYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLD 326
+ + L+E Q + QN+++ +R E S K + + VEL+ ++ Q LD
Sbjct: 237 AATDRICSLQEEQ-QQLREQNELIRERSEKSVEITKQDTK------VELETYKQTRQGLD 289
Query: 327 QLSAEV 332
++ ++V
Sbjct: 290 EMYSDV 295
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 106 bits (265), Expect = 3e-23
Identities = 82/306 (26%), Positives = 150/306 (49%), Gaps = 19/306 (6%)
Query: 32 ERRNLITVCRFSVKTLIDR--SCFETIDDSSPEFNNFAAILEQILSHRLKGQVTWFGYES 89
ER NL+ + + S+K L+ S ++D F ++E L H LK + ++ G
Sbjct: 4 ERANLMHMMKLSIKVLLQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLKVKKSFIGQN- 62
Query: 90 PRSFW---DYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTAL 146
+SF+ + + C + S + S+ N+ + ++ +GRAW+ +ALM+K L++Y+ +
Sbjct: 63 -KSFFGPLELVEKLCPEAS-DIATSVRNLPELKTAVGRGRAWLYLALMQKKLADYLKVLI 120
Query: 147 RDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLK 206
+ FYE A+++ EE ++ G+L+GLN +D + CLKGE LD S VID++ YLK
Sbjct: 121 DNKHLLSEFYEPEALMMEEEGMVIVGLLVGLNVLDANLCLKGEDLD-SQVGVIDFSLYLK 179
Query: 207 YIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQK 266
+Q D E L ++ + D + + ++ K Q E
Sbjct: 180 DVQDLDGGKEHERITDVLDQKNYVEELNRHLSCT-VGDLQTKIDGLEKTNSKLQ--EELS 236
Query: 267 GYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLD 326
+ + L+E Q + QN+++ +R E S K + + VEL+ ++ Q LD
Sbjct: 237 AATDRICSLQEEQ-QQLREQNELIRERSEKSVEITKQDTK------VELETYKQTRQGLD 289
Query: 327 QLSAEV 332
++ ++V
Sbjct: 290 EMYSDV 295
>gi|109240552 RUN and FYVE domain-containing 2 isoform b [Homo
sapiens]
Length = 403
Score = 82.4 bits (202), Expect = 7e-16
Identities = 74/306 (24%), Positives = 133/306 (43%), Gaps = 51/306 (16%)
Query: 30 AVERRNLITVCRFSVKTLIDR--SCFETIDDSSPEFNNFAAILEQILSHRLKGQVTWFGY 87
AVER NL+ + + S+K LI+ S T+D P F ++E L H LK + ++ Y
Sbjct: 8 AVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSY 67
Query: 88 ESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHL--SEYISTA 145
W + L+EK +E I +
Sbjct: 68 NKT------------------------------------IWGPLELVEKLYPEAEEIGAS 91
Query: 146 LRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYL 205
+RD FYE A+++ EE ++ G+L+GLN ID + C+KGE LD S VID++ YL
Sbjct: 92 VRDLPGLNEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLD-SQVGVIDFSMYL 150
Query: 206 KYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQ 265
K + + I + E ++ + + + + E + +S ++ +++ +E+
Sbjct: 151 K---NEEDIGNKERNVQ-IAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEE 206
Query: 266 KGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSL 325
+ + + + + S+NK++L + + K++ E ELQ S Q L
Sbjct: 207 LAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVE------TELQTYKHSRQGL 260
Query: 326 DQLSAE 331
D++ E
Sbjct: 261 DEMYNE 266
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 66.6 bits (161), Expect = 4e-11
Identities = 71/301 (23%), Positives = 130/301 (43%), Gaps = 12/301 (3%)
Query: 54 ETIDDSSPEFNNFAAILEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKV--SQNCICS 111
E I D S + F+ LE +L K + T G + + +WDY KV + + I
Sbjct: 33 EPITDDSTSLHKFSYKLEYLLQFDQKEKATLLG--NKKDYWDYFCACLAKVKGANDGIRF 90
Query: 112 IENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANM-L 170
++++ + +S KGRA+IR +L+ + L++ + + K T +Y + L + + +
Sbjct: 91 VKSISELRTSLGKGRAFIRYSLVHQRLADTLQQCFMNTKVTSDWYYARSPFLQPKLSSDI 150
Query: 171 AGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYL---KYIQSSDSISSDEEELRTLGSS 227
G L L + F +G LD ++P T Y+ S SS L +
Sbjct: 151 VGQLYELTEVQFDLASRGFDLDAAWPTFARRTLTTGSSAYLWKPPSRSSSMSSLVSSYLQ 210
Query: 228 GSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRL-RENQ-LSESVS 285
E + ++ P + F++ + + QL + +K E + +L RENQ L +VS
Sbjct: 211 TQEMVSNFDLNSPLNNEALEGFDEMRL--ELDQLEVREKQLRERMQQLDRENQELRAAVS 268
Query: 286 QNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAEVSLSQTSLDPGQSQ 345
Q LQ + + +L ++ ELQ Q + Q+ E+ L+ G ++
Sbjct: 269 QQGEQLQTERERGRTAAEDNVRLTCLVAELQKQWEVTQATQNTVKELQTCLQGLELGAAE 328
Query: 346 E 346
+
Sbjct: 329 K 329
>gi|116292170 RUN domain containing 2A [Homo sapiens]
Length = 375
Score = 62.4 bits (150), Expect = 7e-10
Identities = 69/233 (29%), Positives = 99/233 (42%), Gaps = 34/233 (14%)
Query: 54 ETIDDSSPEFNNFAAILEQILSHRLKG------------QVTWFGY--ESPRSFWDYIRV 99
E DS A E +L H LK Q F E+ FW Y++
Sbjct: 33 EIASDSDSRVTCLCAQFEAVLQHGLKRSRGLALTAAAIKQAAGFASKTETEPVFWYYVKE 92
Query: 100 ACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDG 159
K S+ + ++S +GRAW+R AL E L Y+ L D FYED
Sbjct: 93 VLNKHELQRFYSLRH---IASDVGRGRAWLRCALNEHSLERYLHMLLADRCRLSTFYEDW 149
Query: 160 AIVLGEE-ANMLAGMLLGLNAIDFSFCLKGEGLDGS---FPAVID--------YTPYLKY 207
+ V+ EE ++ML M GLN+I F+ + + L+G P V D T LK
Sbjct: 150 SFVMDEERSSMLPTMAAGLNSILFAINIDNKDLNGQSKFAPTVSDLLKESTQNVTSLLK- 208
Query: 208 IQSSDSISSDEEELRTLGSSGSESSTPENVGPPF-LMDEN-SWFNKCKRVKQK 258
+S+ +SS E+ T S+ S PE P ++ N S KCK+ ++K
Sbjct: 209 -ESTQGVSSLFREI-TASSAVSILIKPEQETDPLPVVSRNVSADAKCKKERKK 259
>gi|221139728 pleckstrin homology domain containing, family M (with
RUN domain) member 2 [Homo sapiens]
Length = 1019
Score = 46.6 bits (109), Expect = 4e-05
Identities = 45/196 (22%), Positives = 82/196 (41%), Gaps = 8/196 (4%)
Query: 43 SVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKGQVTWFGYESPRSFWDYIRVACR 102
SVK L +S F +D P N +L+++ H L + + + +W + R
Sbjct: 17 SVKKL--QSYFAACEDEIPAIRNHDKVLQRLCEH-LDHALLYGLQDLSSGYWVLVVHFTR 73
Query: 103 KVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIV 162
+ I IE +++V+++ + RAW+ +AL E L Y+ + ++Y A+V
Sbjct: 74 R---EAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALV 130
Query: 163 LG-EEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEEL 221
+ + ++ GL I F L LD + P + DY + D + S
Sbjct: 131 CSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLA-PYMPDYYKPQYLLDFEDRLPSSVHGS 189
Query: 222 RTLGSSGSESSTPENV 237
+L + S T N+
Sbjct: 190 DSLSLNSFNSVTSTNL 205
>gi|122891862 DENN/MADD domain containing 5B [Homo sapiens]
Length = 1274
Score = 46.6 bits (109), Expect = 4e-05
Identities = 26/75 (34%), Positives = 43/75 (57%), Gaps = 2/75 (2%)
Query: 112 IENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIV-LGEEANML 170
I+NM + + + RAWIR++L +K LS+++ L + T++ Y+ A + EE
Sbjct: 853 IQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQF 912
Query: 171 AGMLLGLNAIDFSFC 185
LL LNA+D+ FC
Sbjct: 913 LYHLLSLNAVDY-FC 926
>gi|44889475 RAB6 interacting protein 1 [Homo sapiens]
Length = 1287
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 2/75 (2%)
Query: 112 IENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIV-LGEEANML 170
I+N+ + + K RAW+R+++ +K LS ++ L D + T++ Y+ A + +E
Sbjct: 871 IQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQF 930
Query: 171 AGMLLGLNAIDFSFC 185
LL NA+D+ FC
Sbjct: 931 LYHLLSFNAVDY-FC 944
>gi|40538728 pleckstrin homology domain containing, family M (with
RUN domain) member 1 [Homo sapiens]
Length = 1056
Score = 42.7 bits (99), Expect = 6e-04
Identities = 53/257 (20%), Positives = 105/257 (40%), Gaps = 19/257 (7%)
Query: 93 FWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTT 152
FW ++ K + I +E++ V++ + RAW+R+AL + + Y+ L++
Sbjct: 89 FWPLLKAVTHK---HIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLLQEQARL 145
Query: 153 RRFYEDGAIVL-GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSS 211
+Y+ A++ EE L L GL ++ F K A+++ S
Sbjct: 146 HEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSYKS--------AILNEWTLTPLALSG 197
Query: 212 DSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEE 271
S+ + L T G+ + +++ ++ + ++++ +LT
Sbjct: 198 LCPLSELDPLSTSGAELQRKESLDSISHSSGSEDIEVHHSGHKIRRNQKLTASSL----S 253
Query: 272 LLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAE 331
L +QLS S++ + LLQ H E + + + S +SL ++ E
Sbjct: 254 LDTASSSQLSCSLNSDSCLLQENGSKSPDHCEEPMSCDSDLGTANAE-DSDRSLQEVLLE 312
Query: 332 VSLSQTSLDP--GQSQE 346
S +Q + P G SQE
Sbjct: 313 FSKAQVNSVPTNGLSQE 329
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 37.0 bits (84), Expect = 0.032
Identities = 48/176 (27%), Positives = 74/176 (42%), Gaps = 38/176 (21%)
Query: 219 EELRTLGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLE-------------- 264
E+++TL S + S+ N NS ++QK +LT+E
Sbjct: 583 EKIQTLKSRAAGSAQGNNQAC------NSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKN 636
Query: 265 QKGYLEELLRLREN------QLSESVSQNKILLQRIEDSD----------LAHKLEKEQL 308
Q+ EE R+R N Q +E V +N L QR+E+S+ K+E+EQ
Sbjct: 637 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696
Query: 309 EYIIVELQDQL-KSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKED 363
+ I +LQDQL + + LD + +L Q QD L + E +ED
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLL-IAKEEQED 751
>gi|117414154 sodium channel associated protein 2 isoform b [Homo
sapiens]
Length = 939
Score = 36.2 bits (82), Expect = 0.055
Identities = 30/119 (25%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 212 DSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFNK---CKRVKQKYQLTLEQKGY 268
+S+S + E LR S S++ + + D+ K C + K ++ L++K
Sbjct: 699 ESLSRENECLRKTNESDSDAL---RIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEK-- 753
Query: 269 LEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQ 327
+ E+ + + QL E SQ +L+++E + + K+QL+ VEL++ K+Y +L++
Sbjct: 754 ITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNR 812
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 36.2 bits (82), Expect = 0.055
Identities = 30/119 (25%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 212 DSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFNK---CKRVKQKYQLTLEQKGY 268
+S+S + E LR S S++ + + D+ K C + K ++ L++K
Sbjct: 792 ESLSRENECLRKTNESDSDAL---RIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEK-- 846
Query: 269 LEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQ 327
+ E+ + + QL E SQ +L+++E + + K+QL+ VEL++ K+Y +L++
Sbjct: 847 ITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNR 905
>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
Length = 755
Score = 36.2 bits (82), Expect = 0.055
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 4/99 (4%)
Query: 296 DSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLN 355
DS L LEK + + + Q + S +S + +E S G + QDT
Sbjct: 487 DSSLKTGLEKMRSGKMAPKPQSRCTSTRSAGEAPSE----NQSPSKGPEEASSEVQDTNE 542
Query: 356 VMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLAS 394
V G +D P LG GS +++ Y +L KS+ AS
Sbjct: 543 VHVPGDQDEPQTLGKKGSKNNISVYMTLNQKKSDSSSAS 581
>gi|16306548 seryl-tRNA synthetase [Homo sapiens]
Length = 514
Score = 35.8 bits (81), Expect = 0.072
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 6/90 (6%)
Query: 157 EDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYL---KYIQSSDS 213
E GA+V G L G+L+ L + L+ G G P YTP+ + +Q
Sbjct: 183 EKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPI---YTPFFMRKEVMQEVAQ 239
Query: 214 ISSDEEELRTLGSSGSESSTPENVGPPFLM 243
+S +EEL + GSE S + +L+
Sbjct: 240 LSQFDEELYKVIGKGSEKSDDNSYDEKYLI 269
>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
Length = 3677
Score = 34.7 bits (78), Expect = 0.16
Identities = 41/165 (24%), Positives = 72/165 (43%), Gaps = 14/165 (8%)
Query: 201 YTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDEN------SWFNKCKR 254
Y YLK +Q D I + +RTL ++G E + ++ E W CK+
Sbjct: 2133 YKWYLKELQ--DGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQ 2190
Query: 255 VKQKYQLTLEQKGYLEELLR-LRE--NQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYI 311
+ + + EQK L E R L E L E+ + I L+ ++ L KL EQ++ +
Sbjct: 2191 LSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKL--EQVKLL 2248
Query: 312 IVELQDQLKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNV 356
+ EL + + L++ V +S + P + + + K N+
Sbjct: 2249 VEELPLRQGILKQLNETGGPVLVS-APISPEEQDKLENKLKQTNL 2292
>gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens]
Length = 2341
Score = 34.7 bits (78), Expect = 0.16
Identities = 41/165 (24%), Positives = 72/165 (43%), Gaps = 14/165 (8%)
Query: 201 YTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDEN------SWFNKCKR 254
Y YLK +Q D I + +RTL ++G E + ++ E W CK+
Sbjct: 797 YKWYLKELQ--DGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQ 854
Query: 255 VKQKYQLTLEQKGYLEELLR-LRE--NQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYI 311
+ + + EQK L E R L E L E+ + I L+ ++ L KL EQ++ +
Sbjct: 855 LSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKL--EQVKLL 912
Query: 312 IVELQDQLKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNV 356
+ EL + + L++ V +S + P + + + K N+
Sbjct: 913 VEELPLRQGILKQLNETGGPVLVS-APISPEEQDKLENKLKQTNL 956
>gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens]
Length = 2344
Score = 34.7 bits (78), Expect = 0.16
Identities = 41/165 (24%), Positives = 72/165 (43%), Gaps = 14/165 (8%)
Query: 201 YTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDEN------SWFNKCKR 254
Y YLK +Q D I + +RTL ++G E + ++ E W CK+
Sbjct: 800 YKWYLKELQ--DGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQ 857
Query: 255 VKQKYQLTLEQKGYLEELLR-LRE--NQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYI 311
+ + + EQK L E R L E L E+ + I L+ ++ L KL EQ++ +
Sbjct: 858 LSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKL--EQVKLL 915
Query: 312 IVELQDQLKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNV 356
+ EL + + L++ V +S + P + + + K N+
Sbjct: 916 VEELPLRQGILKQLNETGGPVLVS-APISPEEQDKLENKLKQTNL 959
>gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]
Length = 3562
Score = 34.7 bits (78), Expect = 0.16
Identities = 41/165 (24%), Positives = 72/165 (43%), Gaps = 14/165 (8%)
Query: 201 YTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDEN------SWFNKCKR 254
Y YLK +Q D I + +RTL ++G E + ++ E W CK+
Sbjct: 2018 YKWYLKELQ--DGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQ 2075
Query: 255 VKQKYQLTLEQKGYLEELLR-LRE--NQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYI 311
+ + + EQK L E R L E L E+ + I L+ ++ L KL EQ++ +
Sbjct: 2076 LSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKL--EQVKLL 2133
Query: 312 IVELQDQLKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNV 356
+ EL + + L++ V +S + P + + + K N+
Sbjct: 2134 VEELPLRQGILKQLNETGGPVLVS-APISPEEQDKLENKLKQTNL 2177
>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
Length = 3681
Score = 34.7 bits (78), Expect = 0.16
Identities = 41/165 (24%), Positives = 72/165 (43%), Gaps = 14/165 (8%)
Query: 201 YTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDEN------SWFNKCKR 254
Y YLK +Q D I + +RTL ++G E + ++ E W CK+
Sbjct: 2137 YKWYLKELQ--DGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQ 2194
Query: 255 VKQKYQLTLEQKGYLEELLR-LRE--NQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYI 311
+ + + EQK L E R L E L E+ + I L+ ++ L KL EQ++ +
Sbjct: 2195 LSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKL--EQVKLL 2252
Query: 312 IVELQDQLKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNV 356
+ EL + + L++ V +S + P + + + K N+
Sbjct: 2253 VEELPLRQGILKQLNETGGPVLVS-APISPEEQDKLENKLKQTNL 2296
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,962,100
Number of Sequences: 37866
Number of extensions: 648491
Number of successful extensions: 4197
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 90
Number of HSP's that attempted gapping in prelim test: 4024
Number of HSP's gapped (non-prelim): 260
length of query: 407
length of database: 18,247,518
effective HSP length: 105
effective length of query: 302
effective length of database: 14,271,588
effective search space: 4310019576
effective search space used: 4310019576
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.