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Search of human proteins with 197276594
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197276594 RNA binding motif protein 20 [Homo sapiens]
(1227 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197276594 RNA binding motif protein 20 [Homo sapiens] 2523 0.0
gi|62750354 matrin 3 [Homo sapiens] 100 1e-20
gi|21626466 matrin 3 [Homo sapiens] 100 1e-20
gi|14165466 polypyrimidine tract-binding protein 1 isoform c [Ho... 79 3e-14
gi|14165464 polypyrimidine tract-binding protein 1 isoform b [Ho... 79 3e-14
gi|4506243 polypyrimidine tract-binding protein 1 isoform a [Hom... 79 3e-14
gi|10863997 polypyrimidine tract binding protein 2 [Homo sapiens] 74 9e-13
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 72 3e-12
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 68 6e-11
gi|38569466 ROD1 regulator of differentiation 1 [Homo sapiens] 67 1e-10
gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 ... 63 2e-09
gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 ... 63 2e-09
gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ... 63 2e-09
gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 ... 63 2e-09
gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [... 63 2e-09
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 59 2e-08
gi|62526045 zinc finger protein 638 [Homo sapiens] 59 4e-08
gi|21626468 zinc finger protein 638 [Homo sapiens] 59 4e-08
gi|119943102 CREB binding protein isoform b [Homo sapiens] 58 5e-08
gi|119943104 CREB binding protein isoform a [Homo sapiens] 58 5e-08
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 57 1e-07
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 55 4e-07
gi|210032580 SET domain containing 1B [Homo sapiens] 55 4e-07
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 55 5e-07
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 54 7e-07
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 54 9e-07
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 54 9e-07
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 54 1e-06
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 54 1e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 54 1e-06
>gi|197276594 RNA binding motif protein 20 [Homo sapiens]
Length = 1227
Score = 2523 bits (6539), Expect = 0.0
Identities = 1227/1227 (100%), Positives = 1227/1227 (100%)
Query: 1 MVLAAAMSQDADPSGPEQPDRVACSVPGARASPAPSGPRGMQQPPPPPQPPPPPQAGLPQ 60
MVLAAAMSQDADPSGPEQPDRVACSVPGARASPAPSGPRGMQQPPPPPQPPPPPQAGLPQ
Sbjct: 1 MVLAAAMSQDADPSGPEQPDRVACSVPGARASPAPSGPRGMQQPPPPPQPPPPPQAGLPQ 60
Query: 61 IIQNAAKLLDKNPFSVSNPNPLLPSPASLQLAQLQAQLTLHRLKLAQTAVTNNTAAATVL 120
IIQNAAKLLDKNPFSVSNPNPLLPSPASLQLAQLQAQLTLHRLKLAQTAVTNNTAAATVL
Sbjct: 61 IIQNAAKLLDKNPFSVSNPNPLLPSPASLQLAQLQAQLTLHRLKLAQTAVTNNTAAATVL 120
Query: 121 NQVLSKVAMSQPLFNQLRHPSVITGPHGHAGVPQHAAAIPSTRFPSNAIAFSPPSQTRGP 180
NQVLSKVAMSQPLFNQLRHPSVITGPHGHAGVPQHAAAIPSTRFPSNAIAFSPPSQTRGP
Sbjct: 121 NQVLSKVAMSQPLFNQLRHPSVITGPHGHAGVPQHAAAIPSTRFPSNAIAFSPPSQTRGP 180
Query: 181 GPSMNLPNQPPSAMVMHPFTGVMPQTPGQPAVILGIGKTGPAPATAGFYEYGKASSGQTY 240
GPSMNLPNQPPSAMVMHPFTGVMPQTPGQPAVILGIGKTGPAPATAGFYEYGKASSGQTY
Sbjct: 181 GPSMNLPNQPPSAMVMHPFTGVMPQTPGQPAVILGIGKTGPAPATAGFYEYGKASSGQTY 240
Query: 241 GPETDGQPGFLPSSASTSGSVTYEGHYSHTGQDGQAAFSKDFYGPNSQGSHVASGFPAEQ 300
GPETDGQPGFLPSSASTSGSVTYEGHYSHTGQDGQAAFSKDFYGPNSQGSHVASGFPAEQ
Sbjct: 241 GPETDGQPGFLPSSASTSGSVTYEGHYSHTGQDGQAAFSKDFYGPNSQGSHVASGFPAEQ 300
Query: 301 AGGLKSEVGPLLQGTNSQWESPHGFSGQSKPDLTAGPMWPPPHNQPYELYDPEEPTSDRT 360
AGGLKSEVGPLLQGTNSQWESPHGFSGQSKPDLTAGPMWPPPHNQPYELYDPEEPTSDRT
Sbjct: 301 AGGLKSEVGPLLQGTNSQWESPHGFSGQSKPDLTAGPMWPPPHNQPYELYDPEEPTSDRT 360
Query: 361 PPSFGGRLNNSKQGFIGAGRRAKEDQALLSVRPLQAHELNDFHGVAPLHLPHICSICDKK 420
PPSFGGRLNNSKQGFIGAGRRAKEDQALLSVRPLQAHELNDFHGVAPLHLPHICSICDKK
Sbjct: 361 PPSFGGRLNNSKQGFIGAGRRAKEDQALLSVRPLQAHELNDFHGVAPLHLPHICSICDKK 420
Query: 421 VFDLKDWELHVKGKLHAQKCLVFSENAGIRCILGSAEGTLCASPNSTAVYNPAGNEDYAS 480
VFDLKDWELHVKGKLHAQKCLVFSENAGIRCILGSAEGTLCASPNSTAVYNPAGNEDYAS
Sbjct: 421 VFDLKDWELHVKGKLHAQKCLVFSENAGIRCILGSAEGTLCASPNSTAVYNPAGNEDYAS 480
Query: 481 NLGTSYVPIPARSFTQSSPTFPLASVGTTFAQRKGAGRVVHICNLPEGSCTENDVINLGL 540
NLGTSYVPIPARSFTQSSPTFPLASVGTTFAQRKGAGRVVHICNLPEGSCTENDVINLGL
Sbjct: 481 NLGTSYVPIPARSFTQSSPTFPLASVGTTFAQRKGAGRVVHICNLPEGSCTENDVINLGL 540
Query: 541 PFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEKSAVINGEKLLIRMSKRYKELQLK 600
PFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEKSAVINGEKLLIRMSKRYKELQLK
Sbjct: 541 PFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEKSAVINGEKLLIRMSKRYKELQLK 600
Query: 601 KPGKAVAAIIQDIHSQRERDMFREADRYGPERPRSRSPVSRSLSPRSHTPSFTSCSSSHS 660
KPGKAVAAIIQDIHSQRERDMFREADRYGPERPRSRSPVSRSLSPRSHTPSFTSCSSSHS
Sbjct: 601 KPGKAVAAIIQDIHSQRERDMFREADRYGPERPRSRSPVSRSLSPRSHTPSFTSCSSSHS 660
Query: 661 PPGPSRADWGNGRDSWEHSPYARREEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDK 720
PPGPSRADWGNGRDSWEHSPYARREEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDK
Sbjct: 661 PPGPSRADWGNGRDSWEHSPYARREEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDK 720
Query: 721 AELDERPEGGRPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPG 780
AELDERPEGGRPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPG
Sbjct: 721 AELDERPEGGRPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPG 780
Query: 781 RSRRKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADD 840
RSRRKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADD
Sbjct: 781 RSRRKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADD 840
Query: 841 RKENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESW 900
RKENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESW
Sbjct: 841 RKENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESW 900
Query: 901 YPTNMEELVTVDEVGEEEDFIVEPDIPELEEIVPIDQKDKICPETCLCVTTTLDLDLAQD 960
YPTNMEELVTVDEVGEEEDFIVEPDIPELEEIVPIDQKDKICPETCLCVTTTLDLDLAQD
Sbjct: 901 YPTNMEELVTVDEVGEEEDFIVEPDIPELEEIVPIDQKDKICPETCLCVTTTLDLDLAQD 960
Query: 961 FPKEGVKAVGNGAAEISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPAESETGLSLE 1020
FPKEGVKAVGNGAAEISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPAESETGLSLE
Sbjct: 961 FPKEGVKAVGNGAAEISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPAESETGLSLE 1020
Query: 1021 DSDCYEKEAKGVESSDVHPAPTVQQMSSPKPAEERARQPSPFVDDCKTRGTPEDGACEGS 1080
DSDCYEKEAKGVESSDVHPAPTVQQMSSPKPAEERARQPSPFVDDCKTRGTPEDGACEGS
Sbjct: 1021 DSDCYEKEAKGVESSDVHPAPTVQQMSSPKPAEERARQPSPFVDDCKTRGTPEDGACEGS 1080
Query: 1081 PLEEKASPPIETDLQNQACQEVLTPENSRYVEMKSLEVRSPEYTEVELKQPLSLPSWEPE 1140
PLEEKASPPIETDLQNQACQEVLTPENSRYVEMKSLEVRSPEYTEVELKQPLSLPSWEPE
Sbjct: 1081 PLEEKASPPIETDLQNQACQEVLTPENSRYVEMKSLEVRSPEYTEVELKQPLSLPSWEPE 1140
Query: 1141 DVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSEETAKMSHCRSAVHYRNLQKYLSQLAEE 1200
DVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSEETAKMSHCRSAVHYRNLQKYLSQLAEE
Sbjct: 1141 DVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSEETAKMSHCRSAVHYRNLQKYLSQLAEE 1200
Query: 1201 GLKETEGADSPRPEDSGIVPRFERKKL 1227
GLKETEGADSPRPEDSGIVPRFERKKL
Sbjct: 1201 GLKETEGADSPRPEDSGIVPRFERKKL 1227
>gi|62750354 matrin 3 [Homo sapiens]
Length = 847
Score = 100 bits (248), Expect = 1e-20
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 35/221 (15%)
Query: 399 LNDFHGVAPLHLPHICSICDKKVFDLKDWELHVKGKLHAQKCLVFSE---------NAG- 448
+ DFHG+ P PH+CSICD V K+W H+ G H+++C + E + G
Sbjct: 278 IEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGH 337
Query: 449 -------IRCILGSAEGTLCASPNSTAVYNPAGNEDYASNLGTSYVPIPARSFTQSSPTF 501
++ A G L P S + PA NLG + Q
Sbjct: 338 TMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGP--RGNLGAGNGNLQGPRHMQKG--- 392
Query: 502 PLASVGTTFAQRKGAGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEM 561
R RVVHI + G ++ L PFG ++N++++ N+AF+EM
Sbjct: 393 -----------RVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEM 441
Query: 562 AYTEAAQAMVQYYQEKSAVINGEKLLIRMSKRYKELQLKKP 602
A TE AQA V YY A++ G+ + + +S++YK ++KKP
Sbjct: 442 ATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYK--RIKKP 480
Score = 87.4 bits (215), Expect = 7e-17
Identities = 60/205 (29%), Positives = 99/205 (48%), Gaps = 16/205 (7%)
Query: 1002 LNLDAERKPAESETGLSLEDSDCYEKEAKGVESSDVHPAPTVQQMSSPKPAEERARQPSP 1061
L +D E A E+G S+ D + G +SD P+ + + A A++
Sbjct: 658 LLVDEEEAAALLESGSSVGDET--DLANLGDVASDGKKEPSDKAVKKDGSASAAAKKKLK 715
Query: 1062 FVDDCKTRGTPEDGACEGSPLEEKASPPIETDLQNQACQEVLTPENSRYVEMKSLEVRSP 1121
VD + + A E E+ + P +N T EN+ +
Sbjct: 716 KVDKIEELDQENEAALENGIKNEENTEPGAESSENADDPNKDTSENAD----GQSDENKD 771
Query: 1122 EYTEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSEETAKMSHC 1181
+YT + + ++P ++P+G+++V+P+TGFYCKLC LFYT+EE AK +HC
Sbjct: 772 DYT---IPDEYRIGPYQP-------NVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHC 821
Query: 1182 RSAVHYRNLQKYLSQLAEEGLKETE 1206
S HY+ L+K+L++LAEE ++ E
Sbjct: 822 SSLPHYQKLKKFLNKLAEERRQKKE 846
Score = 87.0 bits (214), Expect = 1e-16
Identities = 79/335 (23%), Positives = 143/335 (42%), Gaps = 51/335 (15%)
Query: 510 FAQRKGAGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQA 569
F Q++ GRV+H+ NLP +++ V+ L P+GK+ NYILM+ +QAF+EM E A A
Sbjct: 488 FDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMA 547
Query: 570 MVQYYQEKSAVINGEKLLIRMSKRYKELQLKKPGKAVAAIIQDIHSQRERDMFREADRYG 629
MV + +K+ G + + +S++YK+L L+ P + + + +D +R Y
Sbjct: 548 MVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRS---------YS 598
Query: 630 PERPRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPSRADWGNGRDSWEHSPYARREEERD 689
P+ S S +S T +G E S + +EE+
Sbjct: 599 PDGKESPS------DKKSKT---------------------DGSQKTESSTEGKEQEEKS 631
Query: 690 PAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHREKYPRSGSPNLPHSV 749
+ D + +P +D+ E E G ++ + NL
Sbjct: 632 GEDGEKDTKDDQTEQEPNMLLESEDELLVDEEEAAALLESGSSVGDE---TDLANLGDVA 688
Query: 750 SSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLGP 809
S DG +KEP DK +K+ A +++K + + +++ E+G+
Sbjct: 689 S------DG--KKEPS---DKAVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKN 737
Query: 810 KVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKEN 844
+ P GA++ +N + K T + +G D ++
Sbjct: 738 EENTEP-GAESSENADDPNKDTSENADGQSDENKD 771
Score = 39.7 bits (91), Expect = 0.018
Identities = 37/177 (20%), Positives = 74/177 (41%), Gaps = 14/177 (7%)
Query: 769 DKYLKQQQDAPGRS---RRKDEARLR----ESRHPHPDDSGKEDGLGPKVTRAPEGAKAK 821
+KY K P R +KD++R R + + D K DG K + EG + +
Sbjct: 570 EKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDG-SQKTESSTEGKEQE 628
Query: 822 QNEKNKTKRTDRDQEGADDRKENTMAENE----AGKEEQEGMEESPQSVGRQEKEAEFSD 877
+ ++ +D + +++ N + E+E +EE + ES SVG + A D
Sbjct: 629 EKSGEDGEKDTKDDQ--TEQEPNMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGD 686
Query: 878 PENTRTKKEQDWESESEAEGESWYPTNMEELVTVDEVGEEEDFIVEPDIPELEEIVP 934
+ K+ D + + + ++++ ++E+ +E + +E I E P
Sbjct: 687 VASDGKKEPSDKAVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEENTEP 743
>gi|21626466 matrin 3 [Homo sapiens]
Length = 847
Score = 100 bits (248), Expect = 1e-20
Identities = 66/221 (29%), Positives = 101/221 (45%), Gaps = 35/221 (15%)
Query: 399 LNDFHGVAPLHLPHICSICDKKVFDLKDWELHVKGKLHAQKCLVFSE---------NAG- 448
+ DFHG+ P PH+CSICD V K+W H+ G H+++C + E + G
Sbjct: 278 IEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGH 337
Query: 449 -------IRCILGSAEGTLCASPNSTAVYNPAGNEDYASNLGTSYVPIPARSFTQSSPTF 501
++ A G L P S + PA NLG + Q
Sbjct: 338 TMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGP--RGNLGAGNGNLQGPRHMQKG--- 392
Query: 502 PLASVGTTFAQRKGAGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEM 561
R RVVHI + G ++ L PFG ++N++++ N+AF+EM
Sbjct: 393 -----------RVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEM 441
Query: 562 AYTEAAQAMVQYYQEKSAVINGEKLLIRMSKRYKELQLKKP 602
A TE AQA V YY A++ G+ + + +S++YK ++KKP
Sbjct: 442 ATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYK--RIKKP 480
Score = 87.4 bits (215), Expect = 7e-17
Identities = 60/205 (29%), Positives = 99/205 (48%), Gaps = 16/205 (7%)
Query: 1002 LNLDAERKPAESETGLSLEDSDCYEKEAKGVESSDVHPAPTVQQMSSPKPAEERARQPSP 1061
L +D E A E+G S+ D + G +SD P+ + + A A++
Sbjct: 658 LLVDEEEAAALLESGSSVGDET--DLANLGDVASDGKKEPSDKAVKKDGSASAAAKKKLK 715
Query: 1062 FVDDCKTRGTPEDGACEGSPLEEKASPPIETDLQNQACQEVLTPENSRYVEMKSLEVRSP 1121
VD + + A E E+ + P +N T EN+ +
Sbjct: 716 KVDKIEELDQENEAALENGIKNEENTEPGAESSENADDPNKDTSENAD----GQSDENKD 771
Query: 1122 EYTEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSEETAKMSHC 1181
+YT + + ++P ++P+G+++V+P+TGFYCKLC LFYT+EE AK +HC
Sbjct: 772 DYT---IPDEYRIGPYQP-------NVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHC 821
Query: 1182 RSAVHYRNLQKYLSQLAEEGLKETE 1206
S HY+ L+K+L++LAEE ++ E
Sbjct: 822 SSLPHYQKLKKFLNKLAEERRQKKE 846
Score = 87.0 bits (214), Expect = 1e-16
Identities = 79/335 (23%), Positives = 143/335 (42%), Gaps = 51/335 (15%)
Query: 510 FAQRKGAGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQA 569
F Q++ GRV+H+ NLP +++ V+ L P+GK+ NYILM+ +QAF+EM E A A
Sbjct: 488 FDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMA 547
Query: 570 MVQYYQEKSAVINGEKLLIRMSKRYKELQLKKPGKAVAAIIQDIHSQRERDMFREADRYG 629
MV + +K+ G + + +S++YK+L L+ P + + + +D +R Y
Sbjct: 548 MVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRS---------YS 598
Query: 630 PERPRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPSRADWGNGRDSWEHSPYARREEERD 689
P+ S S +S T +G E S + +EE+
Sbjct: 599 PDGKESPS------DKKSKT---------------------DGSQKTESSTEGKEQEEKS 631
Query: 690 PAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHREKYPRSGSPNLPHSV 749
+ D + +P +D+ E E G ++ + NL
Sbjct: 632 GEDGEKDTKDDQTEQEPNMLLESEDELLVDEEEAAALLESGSSVGDE---TDLANLGDVA 688
Query: 750 SSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLGP 809
S DG +KEP DK +K+ A +++K + + +++ E+G+
Sbjct: 689 S------DG--KKEPS---DKAVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKN 737
Query: 810 KVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKEN 844
+ P GA++ +N + K T + +G D ++
Sbjct: 738 EENTEP-GAESSENADDPNKDTSENADGQSDENKD 771
Score = 39.7 bits (91), Expect = 0.018
Identities = 37/177 (20%), Positives = 74/177 (41%), Gaps = 14/177 (7%)
Query: 769 DKYLKQQQDAPGRS---RRKDEARLR----ESRHPHPDDSGKEDGLGPKVTRAPEGAKAK 821
+KY K P R +KD++R R + + D K DG K + EG + +
Sbjct: 570 EKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDG-SQKTESSTEGKEQE 628
Query: 822 QNEKNKTKRTDRDQEGADDRKENTMAENE----AGKEEQEGMEESPQSVGRQEKEAEFSD 877
+ ++ +D + +++ N + E+E +EE + ES SVG + A D
Sbjct: 629 EKSGEDGEKDTKDDQ--TEQEPNMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGD 686
Query: 878 PENTRTKKEQDWESESEAEGESWYPTNMEELVTVDEVGEEEDFIVEPDIPELEEIVP 934
+ K+ D + + + ++++ ++E+ +E + +E I E P
Sbjct: 687 VASDGKKEPSDKAVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEENTEP 743
>gi|14165466 polypyrimidine tract-binding protein 1 isoform c [Homo
sapiens]
Length = 531
Score = 78.6 bits (192), Expect = 3e-14
Identities = 47/100 (47%), Positives = 65/100 (65%), Gaps = 4/100 (4%)
Query: 518 RVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEK 577
RV+HI LP TE +VI+LGLPFGKVTN +++K NQAF+EM EAA MV YY
Sbjct: 59 RVIHIRKLPI-DVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSV 117
Query: 578 SAVINGEKLLIRMSKRYKELQL-KKPGKAVA-AIIQDIHS 615
+ V+ G+ + I+ S +KEL+ P +A A A +Q ++S
Sbjct: 118 TPVLRGQPIYIQFS-NHKELKTDSSPNQARAQAALQAVNS 156
>gi|14165464 polypyrimidine tract-binding protein 1 isoform b [Homo
sapiens]
Length = 550
Score = 78.6 bits (192), Expect = 3e-14
Identities = 47/100 (47%), Positives = 65/100 (65%), Gaps = 4/100 (4%)
Query: 518 RVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEK 577
RV+HI LP TE +VI+LGLPFGKVTN +++K NQAF+EM EAA MV YY
Sbjct: 59 RVIHIRKLPI-DVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSV 117
Query: 578 SAVINGEKLLIRMSKRYKELQL-KKPGKAVA-AIIQDIHS 615
+ V+ G+ + I+ S +KEL+ P +A A A +Q ++S
Sbjct: 118 TPVLRGQPIYIQFS-NHKELKTDSSPNQARAQAALQAVNS 156
>gi|4506243 polypyrimidine tract-binding protein 1 isoform a [Homo
sapiens]
Length = 557
Score = 78.6 bits (192), Expect = 3e-14
Identities = 47/100 (47%), Positives = 65/100 (65%), Gaps = 4/100 (4%)
Query: 518 RVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEK 577
RV+HI LP TE +VI+LGLPFGKVTN +++K NQAF+EM EAA MV YY
Sbjct: 59 RVIHIRKLPI-DVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSV 117
Query: 578 SAVINGEKLLIRMSKRYKELQL-KKPGKAVA-AIIQDIHS 615
+ V+ G+ + I+ S +KEL+ P +A A A +Q ++S
Sbjct: 118 TPVLRGQPIYIQFS-NHKELKTDSSPNQARAQAALQAVNS 156
>gi|10863997 polypyrimidine tract binding protein 2 [Homo sapiens]
Length = 531
Score = 73.9 bits (180), Expect = 9e-13
Identities = 41/81 (50%), Positives = 54/81 (66%), Gaps = 2/81 (2%)
Query: 518 RVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEK 577
RV+HI LP G TE +VI LGLPFGKVTN +++K NQAFLE+A EAA MV YY
Sbjct: 59 RVLHIRKLP-GEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAV 117
Query: 578 SAVINGEKLLIRMSKRYKELQ 598
+ + + + I+ S +KEL+
Sbjct: 118 TPHLRNQPIYIQYS-NHKELK 137
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 72.0 bits (175), Expect = 3e-12
Identities = 104/473 (21%), Positives = 183/473 (38%), Gaps = 39/473 (8%)
Query: 684 REEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHREKYPRSG-- 741
+EE + PA + +K + P + K E PE P +E+
Sbjct: 521 KEEAKSPAEAKS--PEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV 578
Query: 742 -SPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARL-RESRHPHPD 799
SP S + +++ + KAK + + A +S K+EA+ E + P
Sbjct: 579 KSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKA 638
Query: 800 DSG-KEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQEG 858
S KE+ P+ ++PE +AK EK K+ + + + K AE ++ ++ +
Sbjct: 639 KSPTKEEAKSPEKAKSPEKEEAKSPEKAKSP-VKAEAKSPEKAKSPVKAEAKSPEKAKSP 697
Query: 859 MEE---SPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEG----ESWYPTNM---EEL 908
++E SP+ KE E PE ++ +++ ++ +A+ E+ P E+
Sbjct: 698 VKEEAKSPEKAKSPVKE-EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKA 756
Query: 909 VTVDEVGEEEDFIVEPDIPELEEIVPIDQKDKICPETCLCVTTTLDLDLAQDFPKEGVKA 968
T+D E + + + P K + E + A+ KE KA
Sbjct: 757 KTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV-------KSPEKAKSPLKEDAKA 809
Query: 969 VGNGAAEISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPAESETGLSLEDSDCYEKE 1028
EI K + P P ++ V+ P + E+ PA +T E D ++E
Sbjct: 810 PEK---EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTE---EKKDSKKEE 863
Query: 1029 AKGVESSDVHPAPTVQQMSSP---KPAEERARQPSPFVDDCKTRGTPEDGACEGSPLEEK 1085
A E+ P P V++ P KP E + +D K TPE A ++E
Sbjct: 864 APKKEA----PKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED 919
Query: 1086 ASPPIETDLQNQACQEVLTPENSRYVEMKSLEVRSPEYTEVELKQPLSLPSWE 1138
A P +T++ + + E S+ E K + E + K+P P E
Sbjct: 920 AKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTE 972
Score = 62.4 bits (150), Expect = 3e-09
Identities = 108/532 (20%), Positives = 189/532 (35%), Gaps = 47/532 (8%)
Query: 596 ELQLKKPGKAVAAIIQDIHSQRERDMFREADRYGPERPRSRSPVSRSLSPRSHTPSFTSC 655
E + K P K A + S + + A+ PE+ +S + P + +P
Sbjct: 513 EKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEA 572
Query: 656 SSSHSPPGPSRADWGNGRDSWEHSPYARREEERDPAPWRDNGDDKRDRMDPWAHDRKH-- 713
S P +A ++ SP + E+ +P ++ + P + K
Sbjct: 573 KSPAEVKSPEKAKSPAKEEA--KSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPA 630
Query: 714 HPRQLDKAELDERPEGGRPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLK 773
+ +KA+ + E P + K P P S E + KAK +
Sbjct: 631 EVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAE---AKSPEKAKSPVKAE 687
Query: 774 QQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKT---KR 830
+ +S K+EA+ E KE+ P+ ++P +AK EK K+ +
Sbjct: 688 AKSPEKAKSPVKEEAKSPEK----AKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEE 743
Query: 831 TDRDQEGADDRKENTM------AENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTK 884
++ K T+ A+ A +E + ++ P+ KE E PE ++
Sbjct: 744 AKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKE-EVKSPEKAKSP 802
Query: 885 KEQDW---ESESEAEGESWYPTNMEEL---VTVDEVGEEEDFIVEPDIPELEEIVPIDQK 938
++D E E + E P EE V V E ++ + P P+ EE D K
Sbjct: 803 LKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEE--KKDSK 860
Query: 939 DKICPETCLCVTTTLD-LDLAQDFPKEGVKAVGNGAAEISLKSPRELPSASTSCPSDMDV 997
+ P+ + + A + PKE AE +++P+ P+ ++V
Sbjct: 861 KEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE----DKKKVPTPEKEAPAKVEV 916
Query: 998 EMPGLNLDAERKPAESETGLSLEDSDCYEKE-AKGVESSDVHPAPTVQQMSSPKPAEERA 1056
+ + KP E E D KE +K E + P + K EE+
Sbjct: 917 K-------EDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKP 969
Query: 1057 RQPSPFVDDCKTRGTPEDGACEGSPLEEKASPPIETDLQNQACQEVLTPENS 1108
+ + +D KT P EKA TD ++ E T + +
Sbjct: 970 KTEAKAKEDDKTLSKE-----PSKPKAEKAEKSSSTDQKDSKPPEKATEDKA 1016
Score = 55.5 bits (132), Expect = 3e-07
Identities = 81/366 (22%), Positives = 141/366 (38%), Gaps = 54/366 (14%)
Query: 806 GLGPKVTRAPEG----------AKAKQNEKNK-TKRTDRDQEGADDRKENTMAENEAGKE 854
G GP PEG K K EK K ++++++ +++ E T E +E
Sbjct: 414 GFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEE 473
Query: 855 EQEGM--EESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNMEELVTVD 912
E++ EE + G +E+EAE + E E+ E EA+ P E +
Sbjct: 474 EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKS----PVKEEAKSPAE 529
Query: 913 EVGEEEDFIVEP-DIPELEEI-VPIDQKDKICPETCLCVTTTLDLDLAQDFPKEGVKAVG 970
E++ P ++ E+ P ++ K PE A+ KE K+
Sbjct: 530 AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPE-------------AKSPEKEEAKSPA 576
Query: 971 NGAAEISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPAESETGLSLEDSDCYEKEAK 1030
+ KSP A S + + P + + P + E E ++EAK
Sbjct: 577 EVKSPEKAKSP-----AKEEAKSPAEAKSP----EKAKSPVKEEAKSPAEAKSPVKEEAK 627
Query: 1031 G---VESSDVHPAPTVQQMSSPK----PAEERARQPSPFVDDCKTRGTPEDGACEGSPLE 1083
V+S + +PT ++ SP+ P +E A+ P K + A SP++
Sbjct: 628 SPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA--KSPVK 685
Query: 1084 EKASPPIETDLQNQACQEVLTPENSRYVEMKSLEVRSPEYTEVELKQPLSLPSWEPEDVF 1143
+A P + ++ +E +PE ++ + E +SPE + +K+ P V
Sbjct: 686 AEAKSPEKA--KSPVKEEAKSPEKAKSPVKE--EAKSPEKAKSPVKEEAKTPEKAKSPVK 741
Query: 1144 SELSIP 1149
E P
Sbjct: 742 EEAKSP 747
Score = 55.5 bits (132), Expect = 3e-07
Identities = 76/348 (21%), Positives = 133/348 (38%), Gaps = 42/348 (12%)
Query: 809 PKVTRAPEGAKAKQNEKNKT-KRTDRDQEGADDRKENTMAENEAGKEEQEGM--EESPQS 865
PK+ K K EK K ++++++ +++ E T E +EE++ EE +
Sbjct: 427 PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486
Query: 866 VGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNMEELVTVDEVGEEEDFIVEPD 925
G +E+EAE + E E+ E EA+ V EE E
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSP---------------VKEEAKSPAEAK 531
Query: 926 IPELEEIV-PIDQKDKICPETCLCVTTTLDLDLAQDFPKEGVKAVGNGAAEISLKSPREL 984
PE EE P + K PE + A+ P+ + +KSP +
Sbjct: 532 SPEKEEAKSPAEVKS---PEKAKSPAK----EEAKSPPEAKSPEKEEAKSPAEVKSPEKA 584
Query: 985 PS-ASTSCPSDMDVEMPGLNLDAERKPAESETGLSLEDSDCYEKEAKG---VESSDVHPA 1040
S A S + + P + + P + E E ++EAK V+S + +
Sbjct: 585 KSPAKEEAKSPAEAKSP----EKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS 640
Query: 1041 PTVQQMSSPK----PAEERARQP----SPFVDDCKTRGTPEDGACEGSPLEEKASPPIET 1092
PT ++ SP+ P +E A+ P SP + K+ + + EKA P++
Sbjct: 641 PTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKE 700
Query: 1093 DLQNQACQEVLTPENSRYVEMKSLEVRSPEYTEVELKQPLSLPSWEPE 1140
+ ++ + E ++ E V+ T + K P+ + PE
Sbjct: 701 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPE 748
Score = 55.5 bits (132), Expect = 3e-07
Identities = 101/464 (21%), Positives = 173/464 (37%), Gaps = 61/464 (13%)
Query: 724 DERPEGGRPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSR 783
+E EGG + P + + P + +E+ E K+ + K + +
Sbjct: 491 EEEAEGGEEETKSPPAEEAAS-PEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEK 549
Query: 784 RKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDR-K 842
K A+ P KE+ P ++PE AK+ E+ K+ + E A K
Sbjct: 550 AKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609
Query: 843 ENTMAENEAG---KEEQEGMEE--SPQSVGRQEKEAEFSDPENTRTKKEQDWES----ES 893
E + EA KEE + E SP+ KE E PE ++ ++++ +S +S
Sbjct: 610 EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE-EAKSPEKAKSPEKEEAKSPEKAKS 668
Query: 894 EAEGESWYPTNMEELVTVD-EVGEEEDFIVEPDIPELEEIVPIDQKDKICPETCLCVT-- 950
+ E+ P + V + + E+ V+ + E+ +++ PE
Sbjct: 669 PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 728
Query: 951 TTLDLDLAQDFPKEGVKAVGNG-----AAEISLKSPRELPSASTSC--PSDMDVEMPGLN 1003
+ A+ KE K+ A + +KSP A P+D E
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788
Query: 1004 LDAERKPAESETGLSLEDSDCYEKEAKGVESSDVHPAPTVQQMSSP-----KPAEERARQ 1058
+ E K E ED+ EKE P +++ SP KP E + ++
Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAPEKE-----------IPKKEEVKSPVKEEEKPQEVKVKE 837
Query: 1059 PSPFVDDCKTRGTP-----EDGACEGSP--------LEEKASPPIETDLQNQA------- 1098
P ++ K TP +D E +P +EEK P +E +++
Sbjct: 838 PPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEA 897
Query: 1099 --CQEVLTPENSRYVEMKSLEVRSP-EYTEVELKQPLSLPSWEP 1139
++V TPE +++ E P E TEV K+P + EP
Sbjct: 898 EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP 941
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 67.8 bits (164), Expect = 6e-11
Identities = 70/275 (25%), Positives = 110/275 (40%), Gaps = 35/275 (12%)
Query: 626 DRYGPERPRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPSRADWGNGRDSWE-HSPYARR 684
DR G R R R P R S SS+S N DSWE S Y
Sbjct: 558 DRMG--RSRGRVPELPEKGSRGSRGSQIDSHSSNS----------NYHDSWETRSSYP-- 603
Query: 685 EEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHREKYPRSGSPN 744
ERD P RDN D RD + +R+H R R +RE+ R SP
Sbjct: 604 --ERDRYPERDNRDQARDS----SFERRHGERDR------------RDNRERDQRPSSP- 644
Query: 745 LPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKE 804
+ H + + D + + D ++ R R +D R RE + KE
Sbjct: 645 IRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKE 704
Query: 805 DGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQEGMEESPQ 864
L + R E + K+ ++ + + D D+E +R+ + E E +EE+E E +
Sbjct: 705 RELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERER 764
Query: 865 SVGRQ-EKEAEFSDPENTRTKKEQDWESESEAEGE 898
R+ E+E E + + ++++DWE + + +
Sbjct: 765 ERERERERERERARERDKERERQRDWEDKDKGRDD 799
Score = 58.9 bits (141), Expect = 3e-08
Identities = 80/309 (25%), Positives = 120/309 (38%), Gaps = 54/309 (17%)
Query: 588 IRMSKRYKELQLKKPGKAVAAIIQDIHSQRERDMFREADRYGPERPRSRSPVSRSLSP-- 645
I + K+YKE K I + ++R E R ++PRS SP + SP
Sbjct: 274 IALGKKYKEKY-----KVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPIS 328
Query: 646 -RSHTPSFTSCSS--SHSP-------PGPS---------RADWGNGRDSWEHSPYARREE 686
R H+ S S SS HSP P PS R SP ++
Sbjct: 329 SRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSP 388
Query: 687 ERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHREKYPRSGSPNLP 746
R +P R+ G +R +HDR+H R+ + + D R + R RE Y + S +
Sbjct: 389 PRHRSPMREKGRHDHERTSQ-SHDRRHERREDTRGKRD-REKDSREERE-YEQDQSSSRD 445
Query: 747 HSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDG 806
H R+D +EP+ D+ + +D R +D +R+SR ++
Sbjct: 446 H-------RDD----REPRDGRDR--RDARDTRDRRELRDSRDMRDSREMRDYSRDTKES 492
Query: 807 LGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGAD-DRKENTMAENEAGKEEQEGMEESPQS 865
P+ +R+ A RD+EG D RKE+T E EES ++
Sbjct: 493 RDPRDSRSTRDA-----------HDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRT 541
Query: 866 VGRQEKEAE 874
R E E
Sbjct: 542 EIRNESRNE 550
Score = 50.8 bits (120), Expect = 8e-06
Identities = 56/258 (21%), Positives = 100/258 (38%), Gaps = 16/258 (6%)
Query: 630 PERPRSRSPVSRSLSPRSHTPSFT---SCSSSHSPPGPSRADWGNGRDSWEHSPYARREE 686
PE P S SR SH+ + S + S P R + RD S + RR
Sbjct: 568 PELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHG 627
Query: 687 ERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHREKYPRSGSPNLP 746
ERD RDN + + P H ++ + D+ + R + R++ R
Sbjct: 628 ERDR---RDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERE 684
Query: 747 HSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDG 806
+ RE R+ K + + + ++ R + +D R R+ H + +E
Sbjct: 685 RDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERE-- 742
Query: 807 LGPKVTRAPEGAKAKQNEKNKTKR-TDRDQEGADDRKENTMAENEAGKEEQEGMEESPQS 865
R E + ++ E+ + +R +R++E +R+ E + +E Q E+ +
Sbjct: 743 ------RDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKG 796
Query: 866 -VGRQEKEAEFSDPENTR 882
R+EK E + N R
Sbjct: 797 RDDRREKREEIREDRNPR 814
Score = 41.2 bits (95), Expect = 0.006
Identities = 62/277 (22%), Positives = 105/277 (37%), Gaps = 39/277 (14%)
Query: 664 PSRADWGNGRDSWEHSPYARREEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAEL 723
PSR+ + +DS HS E R D RDR+ DR H R+ ++
Sbjct: 1259 PSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQ--ERDRYEHDRERERERR 1316
Query: 724 DERPEGGRPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQ--QDAPGR 781
D R + ++ R + P + + RE R+ K + +++ D+ R
Sbjct: 1317 DTR-------QREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVER 1369
Query: 782 SRRKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDR 841
R +D R ES V R AK + + + T RD D
Sbjct: 1370 DRDRDRDRTFESSQIE------------SVKRCE--AKLEGEHERDLESTSRDSLALDKE 1415
Query: 842 KENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWY 901
+ + + G +G EE+ +S + EA D E+ K D S GE +
Sbjct: 1416 R----MDKDLG--SVQGFEETNKSERTESLEA--GDDES----KLDDAHSLGSGAGEGYE 1463
Query: 902 PTNMEEL--VTVDEVGEEEDFIVEPDIPELEEIVPID 936
P + +EL + + + ED E +P+ +++ +D
Sbjct: 1464 PISDDELDEILAGDAEKREDQQDEEKMPDPLDVIDVD 1500
Score = 39.7 bits (91), Expect = 0.018
Identities = 49/257 (19%), Positives = 96/257 (37%), Gaps = 26/257 (10%)
Query: 684 REEERDPAPWRDNGDDKRDRMDPWAHDR-KHHPRQLDKAELDERPEGGRPHREKYPRSGS 742
RE ER+ RD D RDR HDR + R+ D+ + ER R + R
Sbjct: 713 REREREREKERDRERD-RDR----DHDRERERERERDREKEREREREERERERERERERE 767
Query: 743 PNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSG 802
+ R+ +E + W+ K + D RR+ +RE R+P
Sbjct: 768 RERERERERARERDK---ERERQRDWEDKDKGRDD-----RREKREEIREDRNPRDGHDE 819
Query: 803 KEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQEGMEES 862
++ + +P ++ + + + +D G D +++ + +E + S
Sbjct: 820 RKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPS 879
Query: 863 PQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNMEELVTVDEVGEEEDFIV 922
+ RQ + KE+D + E + + ++E V+ + E+ I+
Sbjct: 880 HLTEDRQGR------------WKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEIL 927
Query: 923 EPDIPELEEIVPIDQKD 939
E ++I+ Q +
Sbjct: 928 ESSRMRAQDIIGHHQSE 944
Score = 37.7 bits (86), Expect = 0.068
Identities = 66/306 (21%), Positives = 115/306 (37%), Gaps = 30/306 (9%)
Query: 615 SQRERDMFREADRYGPERPRSRSPVSRSLSPRSH--TPSFTSCSSSHSPPGPSRADWGNG 672
S R + E DRY PER +R S R H + P P R N
Sbjct: 595 SWETRSSYPERDRY-PERD-NRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRND 652
Query: 673 RDSWEHSPYARR----EEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELD-ERP 727
+ RR ++ RD + + +RDR +R+ + + EL+ ER
Sbjct: 653 ELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERA 712
Query: 728 EGGRPHREK-YPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKD 786
REK R + H + RE ++ + + ++ +++++ R R ++
Sbjct: 713 REREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERE---RERERE 769
Query: 787 EARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRD-QEGADDRKENT 845
R RE + ++ K + + + EK + R DR+ ++G D+RK
Sbjct: 770 RERERERARERDKERERQRDWEDK-----DKGRDDRREKREEIREDRNPRDGHDERKSKK 824
Query: 846 MAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEA----EGESWY 901
N EG QS R+ + + SD N+ K + S+ E S
Sbjct: 825 RYRN-------EGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLS 877
Query: 902 PTNMEE 907
P+++ E
Sbjct: 878 PSHLTE 883
Score = 36.2 bits (82), Expect = 0.20
Identities = 62/279 (22%), Positives = 98/279 (35%), Gaps = 54/279 (19%)
Query: 673 RDSWEHSPYAR-REEERDPAPWRDNGD--DKRDRMDPWAH-------------DRKHHPR 716
RDS E Y+R +E RDP R D D RDR H R H
Sbjct: 477 RDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLRE 536
Query: 717 QLDKAEL-----DERPEGGRPHREKYPRSGSPNLPH------------SVSSYKSREDGY 759
+ + E+ +E R R R P LP S SS + D +
Sbjct: 537 ESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSW 596
Query: 760 YRKEPKAKWDKYLKQQQDAPGRS----RRKDEARLRESRH--PHPDDSGKEDGLGPKVTR 813
+ + D+Y ++ R RR E R++R P + G ++ R
Sbjct: 597 ETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELER 656
Query: 814 APEGAKAK-----QNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQEGMEESPQSVGR 868
+ + + + DR++E +R+ E + +E++ +E
Sbjct: 657 DERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERE 716
Query: 869 QEKEAEFSDPENTRTK---------KEQDWESESEAEGE 898
+E+E E D E R + +E+D E E E E E
Sbjct: 717 REREKE-RDRERDRDRDHDRERERERERDREKERERERE 754
Score = 32.3 bits (72), Expect = 2.8
Identities = 28/97 (28%), Positives = 37/97 (38%), Gaps = 19/97 (19%)
Query: 798 PDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQE 857
P GK G R+PE E+ K KR D D E +K NT
Sbjct: 63 PSPRGK--GYSSNYRRSPERPTGDLRERMKNKRQDVDTE---PQKRNT------------ 105
Query: 858 GMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESE 894
EES V ++ + E+ + KE+ ESE E
Sbjct: 106 --EESSSPVRKESSRGRHREKEDIKITKERTPESEEE 140
>gi|38569466 ROD1 regulator of differentiation 1 [Homo sapiens]
Length = 552
Score = 67.0 bits (162), Expect = 1e-10
Identities = 39/94 (41%), Positives = 57/94 (60%), Gaps = 3/94 (3%)
Query: 518 RVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEK 577
RV+H+ +P TE ++I+LGLPFGKVTN +++K +QAFLEMA EAA MV YY
Sbjct: 59 RVLHLRKIP-CDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPI 117
Query: 578 SAVINGEKLLIRMS--KRYKELQLKKPGKAVAAI 609
+ + + + I+ S + K L +A AA+
Sbjct: 118 TPHLRSQPVYIQYSNHRELKTDNLPNQARAQAAL 151
>gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 [Homo
sapiens]
Length = 818
Score = 62.8 bits (151), Expect = 2e-09
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Query: 1057 RQPSPFVDDCKTRGTPEDGACEGSPLEEKASPPIETD---LQNQACQEVLTPENSRYVEM 1113
+ P FV+ K++G +D A E LE++ + E + C E E +
Sbjct: 615 KTPRKFVEHVKSQGH-KDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDE 673
Query: 1114 KSLEVRSPEYTEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSE 1173
+ +EV +V + +S W+ + +S + GV+F+VP G+ C++C FY S
Sbjct: 674 EEIEVEEELCKQVRSRD-ISREEWKGSETYSP-NTAYGVDFLVPVMGYICRICHKFYHSN 731
Query: 1174 ETAKMSHCRSAVHYRNLQKY 1193
A++SHC+S H+ NLQKY
Sbjct: 732 SGAQLSHCKSLGHFENLQKY 751
>gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 [Homo
sapiens]
Length = 837
Score = 62.8 bits (151), Expect = 2e-09
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Query: 1057 RQPSPFVDDCKTRGTPEDGACEGSPLEEKASPPIETD---LQNQACQEVLTPENSRYVEM 1113
+ P FV+ K++G +D A E LE++ + E + C E E +
Sbjct: 634 KTPRKFVEHVKSQGH-KDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDE 692
Query: 1114 KSLEVRSPEYTEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSE 1173
+ +EV +V + +S W+ + +S + GV+F+VP G+ C++C FY S
Sbjct: 693 EEIEVEEELCKQVRSRD-ISREEWKGSETYSP-NTAYGVDFLVPVMGYICRICHKFYHSN 750
Query: 1174 ETAKMSHCRSAVHYRNLQKY 1193
A++SHC+S H+ NLQKY
Sbjct: 751 SGAQLSHCKSLGHFENLQKY 770
>gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 [Homo
sapiens]
Length = 898
Score = 62.8 bits (151), Expect = 2e-09
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Query: 1057 RQPSPFVDDCKTRGTPEDGACEGSPLEEKASPPIETD---LQNQACQEVLTPENSRYVEM 1113
+ P FV+ K++G +D A E LE++ + E + C E E +
Sbjct: 695 KTPRKFVEHVKSQGH-KDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDE 753
Query: 1114 KSLEVRSPEYTEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSE 1173
+ +EV +V + +S W+ + +S + GV+F+VP G+ C++C FY S
Sbjct: 754 EEIEVEEELCKQVRSRD-ISREEWKGSETYSP-NTAYGVDFLVPVMGYICRICHKFYHSN 811
Query: 1174 ETAKMSHCRSAVHYRNLQKY 1193
A++SHC+S H+ NLQKY
Sbjct: 812 SGAQLSHCKSLGHFENLQKY 831
>gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 [Homo
sapiens]
Length = 842
Score = 62.8 bits (151), Expect = 2e-09
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Query: 1057 RQPSPFVDDCKTRGTPEDGACEGSPLEEKASPPIETD---LQNQACQEVLTPENSRYVEM 1113
+ P FV+ K++G +D A E LE++ + E + C E E +
Sbjct: 639 KTPRKFVEHVKSQGH-KDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDE 697
Query: 1114 KSLEVRSPEYTEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSE 1173
+ +EV +V + +S W+ + +S + GV+F+VP G+ C++C FY S
Sbjct: 698 EEIEVEEELCKQVRSRD-ISREEWKGSETYSP-NTAYGVDFLVPVMGYICRICHKFYHSN 755
Query: 1174 ETAKMSHCRSAVHYRNLQKY 1193
A++SHC+S H+ NLQKY
Sbjct: 756 SGAQLSHCKSLGHFENLQKY 775
>gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [Homo
sapiens]
Length = 898
Score = 62.8 bits (151), Expect = 2e-09
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Query: 1057 RQPSPFVDDCKTRGTPEDGACEGSPLEEKASPPIETD---LQNQACQEVLTPENSRYVEM 1113
+ P FV+ K++G +D A E LE++ + E + C E E +
Sbjct: 695 KTPRKFVEHVKSQGH-KDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDE 753
Query: 1114 KSLEVRSPEYTEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSE 1173
+ +EV +V + +S W+ + +S + GV+F+VP G+ C++C FY S
Sbjct: 754 EEIEVEEELCKQVRSRD-ISREEWKGSETYSP-NTAYGVDFLVPVMGYICRICHKFYHSN 811
Query: 1174 ETAKMSHCRSAVHYRNLQKY 1193
A++SHC+S H+ NLQKY
Sbjct: 812 SGAQLSHCKSLGHFENLQKY 831
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 59.3 bits (142), Expect = 2e-08
Identities = 46/153 (30%), Positives = 72/153 (47%), Gaps = 11/153 (7%)
Query: 774 QQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLG-PKVTRAPEGAKAKQNEKNKTKRTD 832
Q++D ++ K EA +E + ++ GKED G K A E K+ E K D
Sbjct: 130 QKEDEEDQNEEKGEAG-KEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGED 188
Query: 833 RDQEGADDRKENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESE 892
++G D+++E E GKE ++G E+ + G+ K E D + KE + +E
Sbjct: 189 GKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKE--DEKEREDGKEDEGGNE 246
Query: 893 SEAEGESWYPTNMEELVTVDEVGEEEDFIVEPD 925
EA E +E + +E G+EED I E D
Sbjct: 247 EEAGKE-------KEDLKEEEEGKEEDEIKEDD 272
Score = 47.4 bits (111), Expect = 9e-05
Identities = 46/212 (21%), Positives = 90/212 (42%), Gaps = 28/212 (13%)
Query: 671 NGRDSWEHSPYARRE----EERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDER 726
NG +P + +E +E + + G +K++ + + + ++ ++ + +E+
Sbjct: 82 NGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEK 141
Query: 727 PEGGRPHR-EKYPRSGSP--NLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSR 783
E G+ + EK G N K +EDG ++ K + ++ +D
Sbjct: 142 GEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGED------ 195
Query: 784 RKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADD--- 840
K+E +E+ ++ GKE G EG K E K + ++ EG ++
Sbjct: 196 EKEEEDRKETGDGKENEDGKEKG------DKKEGKDVKVKEDEKEREDGKEDEGGNEEEA 249
Query: 841 -RKENTMAENEAGKEEQE-----GMEESPQSV 866
+++ + E E GKEE E G +E PQS+
Sbjct: 250 GKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSI 281
Score = 34.7 bits (78), Expect = 0.57
Identities = 26/107 (24%), Positives = 51/107 (47%), Gaps = 8/107 (7%)
Query: 812 TRAPEGAKAKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQEGMEESPQSVGRQEK 871
T A A+ KQ + + + G E +E E + ++E +E++ + G ++K
Sbjct: 58 TSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEK-GGEKK 116
Query: 872 EAEFSDPENTRTKKEQDWESESEAEGESWYPTNMEELVTVDEVGEEE 918
EA ++ +N +++D E ++E +GE+ DE GEE+
Sbjct: 117 EAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDK-------DEKGEED 156
Score = 32.7 bits (73), Expect = 2.2
Identities = 32/160 (20%), Positives = 65/160 (40%), Gaps = 16/160 (10%)
Query: 777 DAPGRSRRKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTK----RTD 832
+AP + E + K++ + +V E K + ++N+ K + D
Sbjct: 89 EAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKED 148
Query: 833 RDQEGADDRKENTMAENEAGKEEQEGMEESPQSVGRQE-KEAEFSDPENTRTKKEQDWES 891
+D++G +D GKE++ G E+ + +++ K+ E K++ + E
Sbjct: 149 KDEKGEED-----------GKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEK 197
Query: 892 ESEAEGESWYPTNMEELVTVDEVGEEEDFIVEPDIPELEE 931
E E E+ E+ + E +D V+ D E E+
Sbjct: 198 EEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKERED 237
>gi|62526045 zinc finger protein 638 [Homo sapiens]
Length = 1978
Score = 58.5 bits (140), Expect = 4e-08
Identities = 31/87 (35%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Query: 517 GRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQE 576
G V+ I LPE CTE DV L PFGKV + +++ +A+LEM + EA A+++Y +
Sbjct: 675 GSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKEAYLEMEFKEAITAIMKYIET 734
Query: 577 KSAVINGE--KLLIRMSKRYKELQLKK 601
I G+ K+ + K+ + ++KK
Sbjct: 735 TPLTIKGKSVKICVPGKKKAQNKEVKK 761
Score = 56.2 bits (134), Expect = 2e-07
Identities = 117/573 (20%), Positives = 223/573 (38%), Gaps = 101/573 (17%)
Query: 710 DRKHHPRQLDKAELD-ERPEGGRPHREKYPRSGSPNLPHSVSSYKSREDGYYR------- 761
++K P+ + + +++ E+ + P S L S S +K + R
Sbjct: 1413 NQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSKFKPTQSSLTRGGSGRIS 1472
Query: 762 ----KEPKAKWDKYLKQQQDAPGRSR--RKDEAR---LRESRHPHPDDS------GKEDG 806
K K + KQ Q+ R ++D++ L E +P + KE+
Sbjct: 1473 ALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEP 1532
Query: 807 LGP----------KVTRAPEGAKAKQNE-KNKTKRTDRDQEGADDRKENTMAENEAGKEE 855
L P +V ++AKQN K K K T ++ + +E ++
Sbjct: 1533 LFPFNLDEFVTVDEVIEEVNPSQAKQNPLKGKRKETLKN-----------VPFSELNLKK 1581
Query: 856 QEGMEESPQSVGRQEKEA---EFSDPENTRTKKEQDWESESEAEGESWYPTNMEELV--- 909
++G +P+ V + E + E+ Q + E E NMEE+V
Sbjct: 1582 KKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVTVDEVIDEE--ELNMEEMVKNS 1639
Query: 910 ----TVDEVGEEEDFIVEPDIPELEEIVPIDQKDKICPETCLCV-----TTTLDLDLAQD 960
T+DE+ +++D I + ++ + +++D + E + V L L+ + D
Sbjct: 1640 NSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERLVTVDEIGEVEELPLNESAD 1699
Query: 961 FPKEGVKAVGN-------GAAEISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPAES 1013
+ GN IS + P + PS + D + L+L + E
Sbjct: 1700 ITFATLNTKGNEGDTVRDSIGFISSQVPED-PSTLVTVDEIQD-DSSDLHLVTLDEVTEE 1757
Query: 1014 ETGLSLEDSDCYEKEAKGV--------ESSDVHPAPTVQQMSSPKPAEERARQPSPFVDD 1065
+ SL D + ++E V E D + Q + P +++ + VD
Sbjct: 1758 DED-SLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKNDHPTDKKGNRKKRAVDT 1816
Query: 1066 CKTR--GTPEDGACEGSPLEEKASPPIETDLQNQA------------CQEVLTPENSRYV 1111
KT+ + G + +EE IE L + ++ + E ++
Sbjct: 1817 KKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGKTLPSEKAVVTEPAKGE 1876
Query: 1112 EMKSLEVRSPEY----TEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCG 1167
E + E +E E K+ + S + V S+ +P ++F+VP+ GF+C +C
Sbjct: 1877 EAFQMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASD--VPEELDFLVPKAGFFCPICS 1934
Query: 1168 LFYTSEETAKMSHCRSAVHYRNLQKYLSQLAEE 1200
LFY+ E+ A +HC+S H +N +K++++ +E
Sbjct: 1935 LFYSGEK-AMTNHCKSTRHKQNTEKFMAKQRKE 1966
Score = 44.3 bits (103), Expect = 7e-04
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 518 RVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEK 577
R VH+ NLPE V+ +GL FGKV +++ + + N+A L++ E+AQ+M + ++
Sbjct: 1009 RFVHLDNLPEDGL--QCVLCVGLQFGKVDHHVFISNRNKAILQLDSPESAQSMYSFLKQN 1066
Query: 578 SAVINGEKLLIRMSKR 593
I L +S +
Sbjct: 1067 PQNIGDHMLTCSLSPK 1082
Score = 43.5 bits (101), Expect = 0.001
Identities = 15/42 (35%), Positives = 24/42 (57%)
Query: 399 LNDFHGVAPLHLPHICSICDKKVFDLKDWELHVKGKLHAQKC 440
+ND++ +P PH+CS+C+ + LKDW H H + C
Sbjct: 413 MNDYYAASPRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESC 454
Score = 40.8 bits (94), Expect = 0.008
Identities = 21/73 (28%), Positives = 45/73 (61%), Gaps = 1/73 (1%)
Query: 519 VVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEKS 578
V+ + NLP + +V +L PFG + + +++ S +A++E+ +AA++MV++Y
Sbjct: 906 VMLVSNLPNKGYSVEEVYDLAKPFGGLKDILILSSHKKAYIEI-NRKAAESMVKFYTCFP 964
Query: 579 AVINGEKLLIRMS 591
+++G +L I M+
Sbjct: 965 VLMDGNQLSISMA 977
Score = 39.7 bits (91), Expect = 0.018
Identities = 48/174 (27%), Positives = 75/174 (43%), Gaps = 15/174 (8%)
Query: 749 VSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLG 808
VSS K PKAK + Q + +S +D+ + S KE GL
Sbjct: 1387 VSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKL------SAKEFGL- 1439
Query: 809 PKVTRAPEGAKAKQNEKNKTKRTDRDQEGAD-----DRKENTMAENEAGKEEQEGMEESP 863
K T A G A+ + K K ++ + G+ K + + + K+ QE E P
Sbjct: 1440 LKPTSARSGL-AESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQE-TEARP 1497
Query: 864 QSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNMEELVTVDEVGEE 917
+ R + + +NT+ K S S+++ E +P N++E VTVDEV EE
Sbjct: 1498 SIMKRDDSNNKTLAEQNTKNPKSTTGRS-SKSKEEPLFPFNLDEFVTVDEVIEE 1550
Score = 32.7 bits (73), Expect = 2.2
Identities = 39/164 (23%), Positives = 63/164 (38%), Gaps = 7/164 (4%)
Query: 961 FPKEGVKAVGNGAAEISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPA-ESETGLSL 1019
F K+ + +G+ SL +LP +++ E PGL + P ESE +
Sbjct: 1062 FLKQNPQNIGDHMLTCSLSPKIDLPEVQIEHDPELEKESPGL----KNSPIDESEVQTAT 1117
Query: 1020 EDSDCYEKEAKGVESSDVHPAPTVQQMSSPKPAEERARQPSPFVDDCKTRGTPEDGACEG 1079
+ E + + + VQQ + E+A S F + T + E
Sbjct: 1118 DSPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEE 1177
Query: 1080 SPLEEKASPPIETDLQN-QACQEVLTPENSRYVEMKSLEVRSPE 1122
PL AS IE +N + C NS +E K E+ +P+
Sbjct: 1178 IPLVASASVSIEQFTENAEECALNQQMFNSD-LEKKGAEIINPK 1220
>gi|21626468 zinc finger protein 638 [Homo sapiens]
Length = 1978
Score = 58.5 bits (140), Expect = 4e-08
Identities = 31/87 (35%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Query: 517 GRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQE 576
G V+ I LPE CTE DV L PFGKV + +++ +A+LEM + EA A+++Y +
Sbjct: 675 GSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKEAYLEMEFKEAITAIMKYIET 734
Query: 577 KSAVINGE--KLLIRMSKRYKELQLKK 601
I G+ K+ + K+ + ++KK
Sbjct: 735 TPLTIKGKSVKICVPGKKKAQNKEVKK 761
Score = 56.2 bits (134), Expect = 2e-07
Identities = 117/573 (20%), Positives = 223/573 (38%), Gaps = 101/573 (17%)
Query: 710 DRKHHPRQLDKAELD-ERPEGGRPHREKYPRSGSPNLPHSVSSYKSREDGYYR------- 761
++K P+ + + +++ E+ + P S L S S +K + R
Sbjct: 1413 NQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSKFKPTQSSLTRGGSGRIS 1472
Query: 762 ----KEPKAKWDKYLKQQQDAPGRSR--RKDEAR---LRESRHPHPDDS------GKEDG 806
K K + KQ Q+ R ++D++ L E +P + KE+
Sbjct: 1473 ALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQNTKNPKSTTGRSSKSKEEP 1532
Query: 807 LGP----------KVTRAPEGAKAKQNE-KNKTKRTDRDQEGADDRKENTMAENEAGKEE 855
L P +V ++AKQN K K K T ++ + +E ++
Sbjct: 1533 LFPFNLDEFVTVDEVIEEVNPSQAKQNPLKGKRKETLKN-----------VPFSELNLKK 1581
Query: 856 QEGMEESPQSVGRQEKEA---EFSDPENTRTKKEQDWESESEAEGESWYPTNMEELV--- 909
++G +P+ V + E + E+ Q + E E NMEE+V
Sbjct: 1582 KKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVTVDEVIDEE--ELNMEEMVKNS 1639
Query: 910 ----TVDEVGEEEDFIVEPDIPELEEIVPIDQKDKICPETCLCV-----TTTLDLDLAQD 960
T+DE+ +++D I + ++ + +++D + E + V L L+ + D
Sbjct: 1640 NSLFTLDELIDQDDCISHSEPKDVTVLSVAEEQDLLKQERLVTVDEIGEVEELPLNESAD 1699
Query: 961 FPKEGVKAVGN-------GAAEISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPAES 1013
+ GN IS + P + PS + D + L+L + E
Sbjct: 1700 ITFATLNTKGNEGDTVRDSIGFISSQVPED-PSTLVTVDEIQD-DSSDLHLVTLDEVTEE 1757
Query: 1014 ETGLSLEDSDCYEKEAKGV--------ESSDVHPAPTVQQMSSPKPAEERARQPSPFVDD 1065
+ SL D + ++E V E D + Q + P +++ + VD
Sbjct: 1758 DED-SLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKNDHPTDKKGNRKKRAVDT 1816
Query: 1066 CKTR--GTPEDGACEGSPLEEKASPPIETDLQNQA------------CQEVLTPENSRYV 1111
KT+ + G + +EE IE L + ++ + E ++
Sbjct: 1817 KKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGKTLPSEKAVVTEPAKGE 1876
Query: 1112 EMKSLEVRSPEY----TEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCG 1167
E + E +E E K+ + S + V S+ +P ++F+VP+ GF+C +C
Sbjct: 1877 EAFQMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASD--VPEELDFLVPKAGFFCPICS 1934
Query: 1168 LFYTSEETAKMSHCRSAVHYRNLQKYLSQLAEE 1200
LFY+ E+ A +HC+S H +N +K++++ +E
Sbjct: 1935 LFYSGEK-AMTNHCKSTRHKQNTEKFMAKQRKE 1966
Score = 44.3 bits (103), Expect = 7e-04
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 518 RVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEK 577
R VH+ NLPE V+ +GL FGKV +++ + + N+A L++ E+AQ+M + ++
Sbjct: 1009 RFVHLDNLPEDGL--QCVLCVGLQFGKVDHHVFISNRNKAILQLDSPESAQSMYSFLKQN 1066
Query: 578 SAVINGEKLLIRMSKR 593
I L +S +
Sbjct: 1067 PQNIGDHMLTCSLSPK 1082
Score = 43.5 bits (101), Expect = 0.001
Identities = 15/42 (35%), Positives = 24/42 (57%)
Query: 399 LNDFHGVAPLHLPHICSICDKKVFDLKDWELHVKGKLHAQKC 440
+ND++ +P PH+CS+C+ + LKDW H H + C
Sbjct: 413 MNDYYAASPRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESC 454
Score = 40.8 bits (94), Expect = 0.008
Identities = 21/73 (28%), Positives = 45/73 (61%), Gaps = 1/73 (1%)
Query: 519 VVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEKS 578
V+ + NLP + +V +L PFG + + +++ S +A++E+ +AA++MV++Y
Sbjct: 906 VMLVSNLPNKGYSVEEVYDLAKPFGGLKDILILSSHKKAYIEI-NRKAAESMVKFYTCFP 964
Query: 579 AVINGEKLLIRMS 591
+++G +L I M+
Sbjct: 965 VLMDGNQLSISMA 977
Score = 39.7 bits (91), Expect = 0.018
Identities = 48/174 (27%), Positives = 75/174 (43%), Gaps = 15/174 (8%)
Query: 749 VSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLG 808
VSS K PKAK + Q + +S +D+ + S KE GL
Sbjct: 1387 VSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKL------SAKEFGL- 1439
Query: 809 PKVTRAPEGAKAKQNEKNKTKRTDRDQEGAD-----DRKENTMAENEAGKEEQEGMEESP 863
K T A G A+ + K K ++ + G+ K + + + K+ QE E P
Sbjct: 1440 LKPTSARSGL-AESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQE-TEARP 1497
Query: 864 QSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNMEELVTVDEVGEE 917
+ R + + +NT+ K S S+++ E +P N++E VTVDEV EE
Sbjct: 1498 SIMKRDDSNNKTLAEQNTKNPKSTTGRS-SKSKEEPLFPFNLDEFVTVDEVIEE 1550
Score = 32.7 bits (73), Expect = 2.2
Identities = 39/164 (23%), Positives = 63/164 (38%), Gaps = 7/164 (4%)
Query: 961 FPKEGVKAVGNGAAEISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPA-ESETGLSL 1019
F K+ + +G+ SL +LP +++ E PGL + P ESE +
Sbjct: 1062 FLKQNPQNIGDHMLTCSLSPKIDLPEVQIEHDPELEKESPGL----KNSPIDESEVQTAT 1117
Query: 1020 EDSDCYEKEAKGVESSDVHPAPTVQQMSSPKPAEERARQPSPFVDDCKTRGTPEDGACEG 1079
+ E + + + VQQ + E+A S F + T + E
Sbjct: 1118 DSPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEE 1177
Query: 1080 SPLEEKASPPIETDLQN-QACQEVLTPENSRYVEMKSLEVRSPE 1122
PL AS IE +N + C NS +E K E+ +P+
Sbjct: 1178 IPLVASASVSIEQFTENAEECALNQQMFNSD-LEKKGAEIINPK 1220
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 58.2 bits (139), Expect = 5e-08
Identities = 68/259 (26%), Positives = 99/259 (38%), Gaps = 29/259 (11%)
Query: 16 PEQPDRVACSVPGARASPAPSGPRGMQQPPPPPQPPPPPQAGLPQIIQNAAKLLDKNPFS 75
P+Q S P + PS P Q P PP QP P P + P + A+ S
Sbjct: 1840 PQQSLPSPTSAPPGTPTQQPSTP---QTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVS 1896
Query: 76 VSNPN--------PLLPSPASLQLA-----QLQAQLTLHRLKLAQTAVTNNTAAATVLNQ 122
P P P PA+++ A + Q Q L+R+ + + T T +Q
Sbjct: 1897 TGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQ 1956
Query: 123 VLSKVAMSQPLFNQLRHPSVITGPHG---HAGVPQHAAAIPSTRFPSNAIAFSPPSQTRG 179
++ V+++ P NQ+ P + + P G A +PQ P P I+ + G
Sbjct: 1957 -MAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQ---PMPGLPRPVISMQAQAAVAG 2012
Query: 180 PG-PSMNLPNQ-PPSAMVMHPFTGVMPQTPGQPAVILGIGKTGPAPATAGFYE----YGK 233
P PS+ P PSA+ T P +P Q +L I K+ P A + Y
Sbjct: 2013 PRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVA 2072
Query: 234 ASSGQTYGPETDGQPGFLP 252
G P QPG P
Sbjct: 2073 NQPGMQPQPGLQSQPGMQP 2091
Score = 36.6 bits (83), Expect = 0.15
Identities = 52/181 (28%), Positives = 73/181 (40%), Gaps = 34/181 (18%)
Query: 26 VPGARASPAPS---GPRGMQQPPPPP-----QPPPPPQ---AGLPQI----------IQN 64
VPGA A P P GP+ Q P PP P PPP AG+P + Q
Sbjct: 786 VPGA-ALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQP 844
Query: 65 AAKLLDKNPFSVSNPNPLLPSPASLQLA-QLQAQLTLHRLKLAQTAVTNNTAAATVLNQV 123
AA P S S P P+P S+ A Q Q+ T+ AQ T
Sbjct: 845 AAPTQPSTPVSSSGQTP-TPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTP-------- 895
Query: 124 LSKVAMSQPLFNQLRHPSVITGPHGHAGVPQHAAAIPSTRFPSNAIAFSPPSQTRGPGPS 183
+ +++ P +Q + V P G + Q AA+I R P+ + S + ++ PGP
Sbjct: 896 VQPPSVATPQSSQQQPTPVHAQPPG-TPLSQAAASI-DNRVPTPSSVASAETNSQQPGPD 953
Query: 184 M 184
+
Sbjct: 954 V 954
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 58.2 bits (139), Expect = 5e-08
Identities = 68/259 (26%), Positives = 99/259 (38%), Gaps = 29/259 (11%)
Query: 16 PEQPDRVACSVPGARASPAPSGPRGMQQPPPPPQPPPPPQAGLPQIIQNAAKLLDKNPFS 75
P+Q S P + PS P Q P PP QP P P + P + A+ S
Sbjct: 1878 PQQSLPSPTSAPPGTPTQQPSTP---QTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVS 1934
Query: 76 VSNPN--------PLLPSPASLQLA-----QLQAQLTLHRLKLAQTAVTNNTAAATVLNQ 122
P P P PA+++ A + Q Q L+R+ + + T T +Q
Sbjct: 1935 TGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQ 1994
Query: 123 VLSKVAMSQPLFNQLRHPSVITGPHG---HAGVPQHAAAIPSTRFPSNAIAFSPPSQTRG 179
++ V+++ P NQ+ P + + P G A +PQ P P I+ + G
Sbjct: 1995 -MAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQ---PMPGLPRPVISMQAQAAVAG 2050
Query: 180 PG-PSMNLPNQ-PPSAMVMHPFTGVMPQTPGQPAVILGIGKTGPAPATAGFYE----YGK 233
P PS+ P PSA+ T P +P Q +L I K+ P A + Y
Sbjct: 2051 PRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVA 2110
Query: 234 ASSGQTYGPETDGQPGFLP 252
G P QPG P
Sbjct: 2111 NQPGMQPQPGLQSQPGMQP 2129
Score = 36.6 bits (83), Expect = 0.15
Identities = 52/181 (28%), Positives = 73/181 (40%), Gaps = 34/181 (18%)
Query: 26 VPGARASPAPS---GPRGMQQPPPPP-----QPPPPPQ---AGLPQI----------IQN 64
VPGA A P P GP+ Q P PP P PPP AG+P + Q
Sbjct: 824 VPGA-ALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQP 882
Query: 65 AAKLLDKNPFSVSNPNPLLPSPASLQLA-QLQAQLTLHRLKLAQTAVTNNTAAATVLNQV 123
AA P S S P P+P S+ A Q Q+ T+ AQ T
Sbjct: 883 AAPTQPSTPVSSSGQTP-TPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTP-------- 933
Query: 124 LSKVAMSQPLFNQLRHPSVITGPHGHAGVPQHAAAIPSTRFPSNAIAFSPPSQTRGPGPS 183
+ +++ P +Q + V P G + Q AA+I R P+ + S + ++ PGP
Sbjct: 934 VQPPSVATPQSSQQQPTPVHAQPPG-TPLSQAAASI-DNRVPTPSSVASAETNSQQPGPD 991
Query: 184 M 184
+
Sbjct: 992 V 992
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 56.6 bits (135), Expect = 1e-07
Identities = 51/234 (21%), Positives = 96/234 (41%), Gaps = 9/234 (3%)
Query: 672 GRDSWEHSPYARREEERDPAPWRD-NGDDKRDRMDPWAHDRKHHPRQLDKAELD----ER 726
GR E P +E + W+ +G+++ + H ++ + + E + E
Sbjct: 682 GRGEMER-PGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEE 740
Query: 727 PEGGRPHREKYPRSGSPNLP-HSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRK 785
EG R E+ G V + +E+G +KE +A ++ +++ D +
Sbjct: 741 EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEE 800
Query: 786 DEARLRESRHPHPDDSGK-EDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKEN 844
E R E + G+ E+G G + EG ++ + + + + ++E + + E
Sbjct: 801 TEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEE 860
Query: 845 TMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGE 898
E E +E +EG E + G E E E + E + E + E E E EGE
Sbjct: 861 EGEEGEGEEEGEEGEGEGEEEEGEGEGEEE-GEGEGEEEEGEGEGEEEGEGEGE 913
Score = 54.7 bits (130), Expect = 5e-07
Identities = 48/237 (20%), Positives = 95/237 (40%), Gaps = 13/237 (5%)
Query: 671 NGRDSWEHSPYARREEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGG 730
+G + W+ + E+++ G+ +++ A + R ++ E ER +G
Sbjct: 664 SGAEHWQDEEREKGEKDKGRGEMERPGEGEKEL----AEKEEWKKRDGEEQEQKEREQGH 719
Query: 731 RPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWD---KYLKQQQDAPGRSRRKDE 787
+ R + G + + KE + K + + ++ +++ R+K+E
Sbjct: 720 QKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE 779
Query: 788 ARLRESRHPHPDDSGK--EDGLGPKVTRAPEGAKAKQNE----KNKTKRTDRDQEGADDR 841
+E + D G+ E+ + EG + + E K + + + + EG ++
Sbjct: 780 RAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839
Query: 842 KENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGE 898
E E E +EE EG E G E+E E + E + E + E E E EGE
Sbjct: 840 GEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE 896
Score = 42.7 bits (99), Expect = 0.002
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 9/130 (6%)
Query: 774 QQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDR 833
++++ G + E E + G+E+G G EG ++ E+ + + +
Sbjct: 879 EEEEGEGEGEEEGEG---EGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEE 935
Query: 834 DQEGA--DDRKENTMAENEAGKEEQEGM---EESPQSVGRQEKEAEFSDPENTRTKKEQD 888
+ EG D E E E EE+EG EE + G +E E E + E +E++
Sbjct: 936 EGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEG-EEGEGEGEEEEGEGEGEEEE 994
Query: 889 WESESEAEGE 898
E E E EGE
Sbjct: 995 GEEEGEEEGE 1004
Score = 41.6 bits (96), Expect = 0.005
Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 7/148 (4%)
Query: 773 KQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAK-QNEKNKTKRT 831
+++ + G + E E ++ + +G G + EG + + E+ + +
Sbjct: 897 EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWE 956
Query: 832 DRDQEGADDRKENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWES 891
++EG + +E E E G E EG EE + G +E+E E E ++E + E
Sbjct: 957 GEEEEGEGEGEEEGEGEGEEG--EGEGEEEEGEGEG-EEEEGEEEGEEEGEGEEEGEGEG 1013
Query: 892 ESEAEGESWYPTNMEELVTVDEVGEEED 919
E E EGE EE + GEEE+
Sbjct: 1014 EEEEEGEVEGEVEGEE---GEGEGEEEE 1038
Score = 39.3 bits (90), Expect = 0.023
Identities = 35/175 (20%), Positives = 68/175 (38%), Gaps = 25/175 (14%)
Query: 753 KSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLGPKVT 812
K E+G +E + + ++ + + G ++E E + G+E+G G
Sbjct: 920 KGEEEG---EEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEE 976
Query: 813 RAPEG--------AKAKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQEGMEESPQ 864
EG + ++ E+ + + ++EG + +E E E E +EG E +
Sbjct: 977 GEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE 1036
Query: 865 SVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNMEELVTVDEVGEEED 919
G +E E + E ++ ++ E E E + E GEEE+
Sbjct: 1037 EEGEEEGEEREKEGEGEENRRNREEEEEEEGK--------------YQETGEEEN 1077
Score = 38.9 bits (89), Expect = 0.030
Identities = 43/171 (25%), Positives = 75/171 (43%), Gaps = 17/171 (9%)
Query: 749 VSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLG 808
VS K++ G P+ + D ++ + G +DE R + G++D
Sbjct: 636 VSEGKAKSVGEAEDGPEGRGDGTC--EEGSSGAEHWQDEER----------EKGEKDKGR 683
Query: 809 PKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQEGMEESPQSVGR 868
++ R EG K + EK + K+ D +++ +R++ + E +E +EG EE
Sbjct: 684 GEMERPGEGEK-ELAEKEEWKKRDGEEQEQKEREQGH--QKERNQEMEEGGEEEHGEGEE 740
Query: 869 QEKEAEFSDPENTRTKKEQDWES-ESEAEGESWYPTNMEELVTVDEVGEEE 918
+E + E + + K+E + E E E E E EE +E GEEE
Sbjct: 741 EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEG-ERKKEERAGKEEKGEEE 790
Score = 36.2 bits (82), Expect = 0.20
Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 11/105 (10%)
Query: 780 GRSRRKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNE----------KNKTK 829
G ++E E ++ G+E+G G + EG + ++ E + + +
Sbjct: 977 GEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEG-EGEEEEEGEVEGEVEGEEGEGEGE 1035
Query: 830 RTDRDQEGADDRKENTMAENEAGKEEQEGMEESPQSVGRQEKEAE 874
+ ++EG + KE EN +EE+E E Q G +E E +
Sbjct: 1036 EEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQ 1080
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 55.1 bits (131), Expect = 4e-07
Identities = 56/286 (19%), Positives = 107/286 (37%), Gaps = 15/286 (5%)
Query: 619 RDMFREADRYGPERPRSRSPVSRSLSPRSHTPSFTSCSSSHSPP-GPSRADWGNGRDSWE 677
R +E D G PR S S+S SP S S + + SR+ + S
Sbjct: 369 RSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRS 428
Query: 678 HSPYARREEERDPAPWRDNGDDKRDRMDPWA--HDRKHHP-----RQLDKAELDERPEG- 729
SP R+ R +P++ D R R A H R P R ++ ER
Sbjct: 429 RSPNKARDCSRSRSPYKAR-DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQ 487
Query: 730 -GRPHREK-YPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDE 787
G P +E+ + RS SP+ +S + ++ + ++Q +P + R + +
Sbjct: 488 LGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQ 547
Query: 788 ARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKENTMA 847
+R H + R+P + ++ ++ ++ D + + +++
Sbjct: 548 SRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSR 607
Query: 848 ENEAGKEEQEGMEESPQSVGRQEK---EAEFSDPENTRTKKEQDWE 890
+ KE+ +P G + ++ SDP + + DW+
Sbjct: 608 PRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWK 653
Score = 45.4 bits (106), Expect = 3e-04
Identities = 64/330 (19%), Positives = 123/330 (37%), Gaps = 28/330 (8%)
Query: 591 SKRYKELQLKKPGKAVAAIIQDIHSQRERDMFREADRYGPERPRSRSPVSRSLSPRSHTP 650
S+ Q + P ++ + + HS+ ++ + R R+R + + S +
Sbjct: 276 SRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKR--NHSRARSRTRKGILSQMGRHSQSR 333
Query: 651 SFTSCSSSHSPPGPSRA---DWG-NGRDSWEHSPYARREEERD----PAPWRDNGDDKRD 702
S + S + P R +W N HS +ERD +P +++G +
Sbjct: 334 SHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSG 393
Query: 703 RMDPWAHDRKHHPRQLDKAELDERPEGGRPHREK-YPRSGSPN----LPHSVSSYKSRED 757
+ ++ H R + +R P++ + RS SPN S S YK+R+
Sbjct: 394 S----PNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDR 449
Query: 758 GYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEG 817
R KA+ + A RSR + ++ R+ H KE + +R+P
Sbjct: 450 SRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERD--HSQLGSPSKE--RDHRRSRSPSK 505
Query: 818 AKAKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSD 877
+ + ++ +K D + + ++ KE SP S R+ +++
Sbjct: 506 ERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSP-SEEREHRQSRSPS 564
Query: 878 PENTRTKKEQDWESESEAEGESWYPTNMEE 907
E R + W S S+ ++ EE
Sbjct: 565 KERDRRR----WRSPSKERERRQSRSSSEE 590
Score = 45.1 bits (105), Expect = 4e-04
Identities = 61/257 (23%), Positives = 98/257 (38%), Gaps = 10/257 (3%)
Query: 630 PERPRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPSRADWGNGRDSWEHSPYARREEERD 689
P R RS + RSH+ S +S S G S +GR S SP +R+ R
Sbjct: 347 PRRGRSHNWSRNPSKERSHSHSRSS-SKERDHRGSSSPRKESGR-SQSGSPNKQRDHSRS 404
Query: 690 PAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHREKYPRSGSPNLPHSV 749
+P + D R R A DR R +KA R R++ RS SPN
Sbjct: 405 RSPNKAR-DRSRSRSPYKARDRSRS-RSPNKARDCSRSRSPYKARDR-SRSRSPNKARDH 461
Query: 750 SSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSR--RKDEARLRESRHPHPDDSGKEDGL 807
S +S R ++ + Q +P + R R+ + +E + S KE
Sbjct: 462 SRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERD- 520
Query: 808 GPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQEGMEESPQSVG 867
+ +R+P + ++ ++ K DR Q + + KE SP S
Sbjct: 521 -HRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSP-SKE 578
Query: 868 RQEKEAEFSDPENTRTK 884
R+ +++ S E ++
Sbjct: 579 RERRQSRSSSEERDHSR 595
Score = 41.6 bits (96), Expect = 0.005
Identities = 47/232 (20%), Positives = 79/232 (34%), Gaps = 28/232 (12%)
Query: 617 RERDMFREADRY-GPERPRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPSRADWGNGRDS 675
+ RD R Y +R RSRSP RS +P+ S P R
Sbjct: 433 KARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKER--------- 483
Query: 676 WEHSPYARREEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHRE 735
+HS +ERD R +++ R + + H R ++ +R + P++E
Sbjct: 484 -DHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKE 542
Query: 736 K---YPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRE 792
+ RS S H S S+E + +W +P + R + ++R
Sbjct: 543 RDRSQSRSPSEEREHRQSRSPSKE------RDRRRWR--------SPSKERERRQSRSSS 588
Query: 793 SRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKEN 844
H G RA KA + +K + Q ++ +
Sbjct: 589 EERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESD 640
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 55.1 bits (131), Expect = 4e-07
Identities = 82/383 (21%), Positives = 134/383 (34%), Gaps = 65/383 (16%)
Query: 736 KYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRH 795
K R P+ S + R +E + + + D P ++D + R
Sbjct: 963 KVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRR 1022
Query: 796 PHPD---DSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKEN------TM 846
P DSG E+ ++ E + ++ + + + D D + +DDR E+ T
Sbjct: 1023 PARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTA 1082
Query: 847 AENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNME 906
+ K+E + EE S+ + EA S + + + ++ES SE+ S + E
Sbjct: 1083 LSEASEKDEGDSDEEETVSIVTSKAEATSS----SESSESSEFESSSESSPSS--SEDEE 1136
Query: 907 ELVTVDEVGEEEDFIVEPDIPELEEIVPIDQKDKICPETCLCVTTTLDLDLAQDFPKEGV 966
E+V +E EEE+ EE+V + PE D QD +E
Sbjct: 1137 EVVAREEEEEEEE----------EEMVAEESMASAGPE-----------DFEQD-GEEAA 1174
Query: 967 KAVGNGAA-----------EISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPAESET 1015
A G A E +P E PS P + VE P + + +P S+
Sbjct: 1175 LAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQE 1234
Query: 1016 GLSLEDSDCYEKEAK-----GVESSDVH------------PAPTVQQMSSPKPAEERARQ 1058
G L + KE + E + H P P + P+P +
Sbjct: 1235 GAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPP 1294
Query: 1059 PSPFVDDCKTRGTPEDGACEGSP 1081
P P D P + E P
Sbjct: 1295 PEPETTDASHPSVPPEPLAEDHP 1317
Score = 39.3 bits (90), Expect = 0.023
Identities = 18/41 (43%), Positives = 19/41 (46%)
Query: 19 PDRVACSVPGARASPAPSGPRGMQQPPPPPQPPPPPQAGLP 59
P A + P A P P P PPP PPPPPQ G P
Sbjct: 664 PGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFP 704
Score = 35.4 bits (80), Expect = 0.34
Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 18/89 (20%)
Query: 1 MVLAAAMSQDADPS--GPEQPDRVACSVPGARASPAPSGPR-GMQQPPPPPQPPPPPQAG 57
MV+ + A PS P P P P P P+ G PPP P PPPPP
Sbjct: 660 MVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPA 719
Query: 58 LPQIIQNAAKLLDKNPFSVSNPNPLLPSP 86
P +V+ P P LP+P
Sbjct: 720 HP---------------AVTVPPPPLPAP 733
Score = 32.3 bits (72), Expect = 2.8
Identities = 16/32 (50%), Positives = 16/32 (50%), Gaps = 4/32 (12%)
Query: 28 GARASPAPSGPRGMQQPPPPPQPPPPPQAGLP 59
G A P P P QPPPPP PPP LP
Sbjct: 1535 GIPAPPPPLPP----QPPPPPPPPPVEPTKLP 1562
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 54.7 bits (130), Expect = 5e-07
Identities = 111/493 (22%), Positives = 181/493 (36%), Gaps = 76/493 (15%)
Query: 624 EADRYGPERPRSR----SPVSRSLSPRSHTP-SFTSCSSSHSPPGPSRADWGNGRDSWEH 678
+ +R+ P P S+ SPVS S H+P S +S + HSP PS + H
Sbjct: 1838 KTERHPPVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHSPVSPSTK-------TERH 1890
Query: 679 SPYARREEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAE--LDERPEGGRPHREK 736
SP + + ER P DKR + P KH P + E L P G +
Sbjct: 1891 SPVSSTKTERHPPVSPSGKTDKRPPVSPSGRTEKHPPVSPGRTEKRLPVSPSGRTDKHQP 1950
Query: 737 YPRSG--SPNLPHSVSSYKSRE------DGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEA 788
+G +LP S S ++ R E + +K Q S+ K
Sbjct: 1951 VSTAGKTEKHLPVSPSGKTEKQPPVSPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGL 2010
Query: 789 -RLRESRHPHPDDSGK---EDGLGPKVTRAPEGAKAKQNEKNKTKRTDR-DQEGADDRKE 843
+ ++ P + GK E GP +T+ +A++ E KR R G + K
Sbjct: 2011 FEHKSAKQKQPQEKGKVRVEKEKGPILTQ----REAQKTENQTIKRGQRLPVTGTAESKR 2066
Query: 844 NTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPT 903
+ K+E + G +EK PE ++ E++ ESE E
Sbjct: 2067 GVRVSSIGVKKE--------DAAGGKEKVLSHKIPEPVQSVPEEESHRESEVPKEK---- 2114
Query: 904 NMEELVTVDEVGEEEDFIVEPD---IPELEEIVPIDQKD-------KICPET---CLCVT 950
DE G + D + PD + E++ + +D ++ ET L +
Sbjct: 2115 ------MADEQG-DMDLQISPDRKTSTDFSEVIKQELEDNDKYQQFRLSEETEKAQLHLD 2167
Query: 951 TTLDLDLAQDFPKEGVK-------AVGNGAAEISLKSPRELPSASTSCPSDMDVEMPGLN 1003
L FP + +K ++ +GA + S +S + A + C S M+ P ++
Sbjct: 2168 QVLTSPFNTTFPLDYMKDEFLPALSLQSGALDGSSESLKNEGVAGSPCGSLME-GTPQIS 2226
Query: 1004 LDAERKPAESETGLSLEDSDCYEKEAKGVESSDVHPAPTVQQMSSPKPAEERARQPSPFV 1063
+ K GL+ E + + S+ T + + E R+ + P
Sbjct: 2227 SEESYK----HEGLAETPETSPESLSFSPKKSEEQTGETKESTKTETTTEIRSEKEHPTT 2282
Query: 1064 DDCKTRGTPEDGA 1076
D T G+ E GA
Sbjct: 2283 KDI-TGGSEERGA 2294
Score = 45.4 bits (106), Expect = 3e-04
Identities = 84/365 (23%), Positives = 139/365 (38%), Gaps = 42/365 (11%)
Query: 799 DDSGKEDGLGPKVTRAPEGA----KAKQNEKNKTKRTDRDQEGADDR--KENTMAENEAG 852
++S K +GL +PE K + + +TK + + + + R KE+ ++ G
Sbjct: 2228 EESYKHEGLAETPETSPESLSFSPKKSEEQTGETKESTKTETTTEIRSEKEHPTTKDITG 2287
Query: 853 KEEQEGM---EESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNMEELV 909
E+ G E+S S +KEA P++T K++ D PT + E
Sbjct: 2288 GSEERGATVTEDSETSTESFQKEATLGSPKDTSPKRQDDCTGSCSVALAKETPTGLTEEA 2347
Query: 910 TVDE---VGEEEDFIVEPDIPELEEIVPIDQKDKICPETCLCVTTTLDLDLAQDFPKEGV 966
DE + D E++E + K P V T D + +GV
Sbjct: 2348 ACDEGQRTFGSSAHKTQTD-SEVQESTATSDETKALPLPEASVKT----DTGTESKPQGV 2402
Query: 967 KAVGNGAAEISLKSPRELPSASTSCPSDMDVE-------MPGLNLDAERKPAESETGLSL 1019
G E++L S R+ S + V P L ++ K +S L
Sbjct: 2403 IRSPQG-LELALPS-RDSEVLSAVADDSLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPL 2460
Query: 1020 EDSDCYEKEAKGVESSDVHPAPTVQQMSS--PKPAEERARQPSPFVDDCKTRGTPE-DGA 1076
++S C + +ESS V P S P PA + V ++R + DG+
Sbjct: 2461 KESPCRD----SLESSPVEPKMKAGIFPSHFPLPAAVAKTELLTEVASVRSRLLRDPDGS 2516
Query: 1077 CEGSPLEEKASPPIETDLQNQACQEVLTPENSRYVEMKSLEVRSPEYTEVELKQPLSLPS 1136
E LE +T L + + L+P+ E+ S EV +P+ T+V +P +
Sbjct: 2517 AEDDSLE-------QTSLMESSGKSPLSPDTPSSEEV-SYEV-TPKTTDVSTPKPAVIHE 2567
Query: 1137 WEPED 1141
ED
Sbjct: 2568 CAEED 2572
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 54.3 bits (129), Expect = 7e-07
Identities = 55/255 (21%), Positives = 105/255 (41%), Gaps = 31/255 (12%)
Query: 673 RDSWEHSPYARREEERDPAPWRDNGDDKRD--RMDPWAHDRKHHPRQLDKAE-LDERPEG 729
++ W+H+ RE ER + +R+ R R+H R+ D+ E L+ + E
Sbjct: 106 KEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRER 165
Query: 730 GRPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEAR 789
R RE+ K RE R+ + + ++ +++ A R+ R+D +
Sbjct: 166 ERKMREQQKEQ---------REQKERE----RRAEERRKEREARREVSAHHRTMREDYSD 212
Query: 790 LRESRH-----PHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKEN 844
++ H P P E G +G K + EK + + D + D +
Sbjct: 213 KVKASHWSRSPPRPPRERFELG---------DGRKPVKEEKMEERDLLSDLQDISDSERK 263
Query: 845 TMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTN 904
T + + E G EE + +E+E S+ ++E++ E E+ + E +
Sbjct: 264 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS 323
Query: 905 MEELVTVDEVGEEED 919
EE V+ +E+ E+E+
Sbjct: 324 AEE-VSEEEMSEDEE 337
Score = 51.2 bits (121), Expect = 6e-06
Identities = 62/291 (21%), Positives = 123/291 (42%), Gaps = 37/291 (12%)
Query: 677 EHSPYARREEERDPA--PW---------RDNGDDKRDRMDPWAHDRKHHPRQLDKAELDE 725
EH R EE+D A W R++ +RDR++ R+ R++ + + ++
Sbjct: 118 EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERE-RKMREQQKEQ 176
Query: 726 RPEGGRPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRK 785
R + R R + R + +++ + Y K + W + +P R R
Sbjct: 177 REQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR-------SPPRPPR- 228
Query: 786 DEARLRESRHPHPDDSGKEDGLGPKVT------RAPEGAKAKQNEKNKTKRTDRDQEGAD 839
+ L + R P ++ +E L + R A++ E + ++E +
Sbjct: 229 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 288
Query: 840 DRKENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESE----A 895
+ + +T E+E +EE+E EE ++ E+ +E S E + + +D E E+E
Sbjct: 289 EEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 346
Query: 896 EGESWYPTNM-EELVTVDEVGE---EEDFIVEPD-IPELEEIVPIDQKDKI 941
ES + + E +EVGE + + E D +P+ ++PI+ K ++
Sbjct: 347 VPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQEL 397
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 53.9 bits (128), Expect = 9e-07
Identities = 54/250 (21%), Positives = 98/250 (39%), Gaps = 18/250 (7%)
Query: 683 RREEERDPAPWRDNGDDKRDRMDPWAHDR-KHHPRQLDKAELDERPEGGRPHREKYPRSG 741
R+E+ R + + G R + H+R K H + DKA R E R R + R
Sbjct: 71 RKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKA----RREWERQKRREMAREH 126
Query: 742 SPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHP--- 798
S + + + + + + K + K+++ R++ EAR S H
Sbjct: 127 SRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE 186
Query: 799 --DDSGKEDGLGPKVTRAP-------EGAKAKQNEKNKTKRTDRDQEGADDRKENTMAEN 849
D K R P +G K + EK + + D + D + T +
Sbjct: 187 DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAE 246
Query: 850 EAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNMEELV 909
+ E G EE + +E+E S+ ++E++ E E+ + E + EE V
Sbjct: 247 SSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE-V 305
Query: 910 TVDEVGEEED 919
+ +E+ E+E+
Sbjct: 306 SEEEMSEDEE 315
Score = 44.7 bits (104), Expect = 6e-04
Identities = 91/393 (23%), Positives = 146/393 (37%), Gaps = 39/393 (9%)
Query: 710 DRKHHPRQLDKAELDERPEGGRPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWD 769
DR L++ EL R HR + SP + ED +P +
Sbjct: 6 DRDSKRDSLEEGEL-------RDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMS 58
Query: 770 KYLKQQQDAPGRSRRKDEARLRESRH-PHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKT 828
+ K RKDE R + RH H + GK + K R E K + E++K
Sbjct: 59 RKEKVHH-------RKDEKRKEKRRHRSHSAEGGKHARVKEK-EREHERRKRHREEQDKA 110
Query: 829 KRTDRDQEGADDRKENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQD 888
+R Q+ + +E++ E + E+ E E + + Q+KE + E R +E+
Sbjct: 111 RREWERQKRREMAREHSRRERDR-LEQLERKRERERKMREQQKE-QREQKERERRAEERR 168
Query: 889 WESESEAEGESWYPTNMEELVTVDEVGEEEDFIVEPDIPELEEIVPIDQKDKICPETCLC 948
E E+ E + + T E+ D+V + + P P E D + + E
Sbjct: 169 KEREARREVSAHHRTMREDY--SDKV-KASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 225
Query: 949 VTTTLDLDLAQDFPKEGVKA------VGNGAAEISLKSPRELPSASTSCPSDMDVEMPGL 1002
DL D ++ A G+G+ E + E STS S+ + E
Sbjct: 226 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE---- 281
Query: 1003 NLDAERKPAESETGLSLEDSDCYEKEAKGVE--SSDVHPAPTVQQMSSPKPAEERARQPS 1060
E + E ETG + E++ E E S D + P+ +R S
Sbjct: 282 ----EEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 337
Query: 1061 PFVDDCKTRGTPEDGA-CEGSPL-EEKASPPIE 1091
++ GTP+ A EG + + A PIE
Sbjct: 338 EEAEEEVGEGTPQSSALTEGDYVPDSPALSPIE 370
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 53.9 bits (128), Expect = 9e-07
Identities = 54/250 (21%), Positives = 98/250 (39%), Gaps = 18/250 (7%)
Query: 683 RREEERDPAPWRDNGDDKRDRMDPWAHDR-KHHPRQLDKAELDERPEGGRPHREKYPRSG 741
R+E+ R + + G R + H+R K H + DKA R E R R + R
Sbjct: 105 RKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKA----RREWERQKRREMAREH 160
Query: 742 SPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHP--- 798
S + + + + + + K + K+++ R++ EAR S H
Sbjct: 161 SRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE 220
Query: 799 --DDSGKEDGLGPKVTRAP-------EGAKAKQNEKNKTKRTDRDQEGADDRKENTMAEN 849
D K R P +G K + EK + + D + D + T +
Sbjct: 221 DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAE 280
Query: 850 EAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNMEELV 909
+ E G EE + +E+E S+ ++E++ E E+ + E + EE V
Sbjct: 281 SSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE-V 339
Query: 910 TVDEVGEEED 919
+ +E+ E+E+
Sbjct: 340 SEEEMSEDEE 349
Score = 48.9 bits (115), Expect = 3e-05
Identities = 101/442 (22%), Positives = 165/442 (37%), Gaps = 59/442 (13%)
Query: 670 GNGRDSWEHSPY-------ARREEERDPAPWR--DNGDDKRDRMDPWAHDRKHHPRQLDK 720
G+ +DSW+ RR+E+ + A + N DD+ + D L++
Sbjct: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRD-----------SLEE 50
Query: 721 AELDERPEGGRPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPG 780
EL R HR + SP + ED +P + + K
Sbjct: 51 GEL-------RDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHH---- 99
Query: 781 RSRRKDEARLRESRH-PHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGAD 839
RKDE R + RH H + GK + K R E K + E++K +R Q+ +
Sbjct: 100 ---RKDEKRKEKRRHRSHSAEGGKHARVKEK-EREHERRKRHREEQDKARREWERQKRRE 155
Query: 840 DRKENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGES 899
+E++ E + E+ E E + + Q+KE + E R +E+ E E+ E +
Sbjct: 156 MAREHSRRERDR-LEQLERKRERERKMREQQKE-QREQKERERRAEERRKEREARREVSA 213
Query: 900 WYPTNMEELVTVDEVGEEEDFIVEPDIPELEEIVPIDQKDKICPETCLCVTTTLDLDLAQ 959
+ T E+ D+V + + P P E D + + E DL
Sbjct: 214 HHRTMREDY--SDKV-KASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDIS 270
Query: 960 DFPKEGVKA------VGNGAAEISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPAES 1013
D ++ A G+G+ E + E STS S+ + E E + E
Sbjct: 271 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE--------EEEEEEE 322
Query: 1014 ETGLSLEDSDCYEKEAKGVE--SSDVHPAPTVQQMSSPKPAEERARQPSPFVDDCKTRGT 1071
ETG + E++ E E S D + P+ +R S ++ GT
Sbjct: 323 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGT 382
Query: 1072 PEDGA-CEGSPL-EEKASPPIE 1091
P+ A EG + + A PIE
Sbjct: 383 PQSSALTEGDYVPDSPALSPIE 404
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 53.5 bits (127), Expect = 1e-06
Identities = 45/177 (25%), Positives = 74/177 (41%), Gaps = 16/177 (9%)
Query: 727 PEGGRPHREKYPRSGSPNLPHSVSSYKS--REDGYYRKEPKAKWDKYLKQQQD-----AP 779
PE G+ + K RS S S SS KS R K ++ +Q+D +P
Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 354
Query: 780 GRSRRKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGAD 839
+ R K R + H D K+ TR E K K+ K K + +R++E
Sbjct: 355 HKKRSKSRERRKSRSRSHSRDKRKD-------TR--EKIKEKERVKEKDREKEREREKER 405
Query: 840 DRKENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAE 896
++++ + KE ++ E+ + +E+E E + +KEQD E E E +
Sbjct: 406 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 462
Score = 47.4 bits (111), Expect = 9e-05
Identities = 73/382 (19%), Positives = 139/382 (36%), Gaps = 28/382 (7%)
Query: 518 RVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEK 577
R V++ NL + T + ++ G+V ++ M A+ E A Q +
Sbjct: 182 RTVYVGNLNSQTTTADQLLEFFKQVGEV-KFVRMAGDETQPTRFAFVEFAD---QNSVPR 237
Query: 578 SAVINGEKLLIRMSK--RYKELQLKKPGKAVAAIIQDIHSQRERDMFREADRY---GPER 632
+ NG R K +K P A +++ +R REA + E
Sbjct: 238 ALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKR--VREAQSFISAAIEP 295
Query: 633 PRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPSRADWGNGRDSWEHSPYARREEERDPAP 692
+S + RSHT S S SSS S R+ + S S +++ R +P
Sbjct: 296 ESGKSNERKGGRSRSHTRS-KSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 354
Query: 693 WRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHREKYPRSGSPNLPHSVSSY 752
+ R+R + R+ + ++ E+ REK
Sbjct: 355 HKKRSKS-RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE--------------- 398
Query: 753 KSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLGPKVT 812
+ RE +++ + K K+++ + + KD R RE H D KE +
Sbjct: 399 REREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKE 458
Query: 813 RAPEGAKAKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQEGMEESPQSVGRQEKE 872
R + +K ++ K K++ + + + + E + SP++ +++
Sbjct: 459 REKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK 518
Query: 873 AEFSDPENTRTKKEQDWESESE 894
+ S +R KK++ E E +
Sbjct: 519 SSRSPSPRSRNKKDKKREKERD 540
Score = 47.0 bits (110), Expect = 1e-04
Identities = 60/299 (20%), Positives = 115/299 (38%), Gaps = 16/299 (5%)
Query: 614 HSQRERDMFREADRYGPERPRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPSRADWGNGR 673
HS+R+R + R R RSR R RS +P S SR+ + R
Sbjct: 323 HSRRKRSQSKHRSR-SHNRSRSRQKDRR----RSKSPHKKRSKSRERRKSRSRSHSRDKR 377
Query: 674 -DSWEHSPYARREEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKA---ELDERPEG 729
D+ E R +E+D R+ ++ + + + R+ D+ E D E
Sbjct: 378 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 437
Query: 730 GRPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEAR 789
+ H + + K R K K K + + +A RSR R
Sbjct: 438 EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRER 497
Query: 790 LRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRD--QEGADDRKENTMA 847
R + K +R+P + +N+K+K + +RD E + + +M
Sbjct: 498 RRRRSRSSSRSPRTSKTIKRKSSRSP--SPRSRNKKDKKREKERDHISERRERERSTSMR 555
Query: 848 ENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNME 906
++ ++ +E +E++ S+ +E E P+++ +K+ D ++ E + + N +
Sbjct: 556 KSSNDRDGKEKLEKNSTSLKEKEHNKE---PDSSVSKEVDDKDAPRTEENKIQHNGNCQ 611
Score = 32.7 bits (73), Expect = 2.2
Identities = 40/170 (23%), Positives = 66/170 (38%), Gaps = 27/170 (15%)
Query: 611 QDIHSQRERDMFREADRYGPERPRSRSPV--------------------SRSLSPRSHTP 650
QD +RE+D +E D + +SR+P SRS S T
Sbjct: 453 QDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTS 512
Query: 651 SFTSCSSSHSPPGPSRADWGNGRDSWEHSPYARREEERDPAPWRDNGD-DKRDRMD--PW 707
SS SP SR R+ RRE ER + + + D D +++++
Sbjct: 513 KTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNST 572
Query: 708 AHDRKHHPRQLDKA---ELDERPEGGRPHREKYPRSGSPNLPHSVSSYKS 754
+ K H ++ D + E+D++ + R K +G+ L S K+
Sbjct: 573 SLKEKEHNKEPDSSVSKEVDDK-DAPRTEENKIQHNGNCQLNEENLSTKT 621
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 53.5 bits (127), Expect = 1e-06
Identities = 45/177 (25%), Positives = 74/177 (41%), Gaps = 16/177 (9%)
Query: 727 PEGGRPHREKYPRSGSPNLPHSVSSYKS--REDGYYRKEPKAKWDKYLKQQQD-----AP 779
PE G+ + K RS S S SS KS R K ++ +Q+D +P
Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 238
Query: 780 GRSRRKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGAD 839
+ R K R + H D K+ TR E K K+ K K + +R++E
Sbjct: 239 HKKRSKSRERRKSRSRSHSRDKRKD-------TR--EKIKEKERVKEKDREKEREREKER 289
Query: 840 DRKENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAE 896
++++ + KE ++ E+ + +E+E E + +KEQD E E E +
Sbjct: 290 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 346
Score = 47.4 bits (111), Expect = 9e-05
Identities = 73/382 (19%), Positives = 139/382 (36%), Gaps = 28/382 (7%)
Query: 518 RVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEK 577
R V++ NL + T + ++ G+V ++ M A+ E A Q +
Sbjct: 66 RTVYVGNLNSQTTTADQLLEFFKQVGEV-KFVRMAGDETQPTRFAFVEFAD---QNSVPR 121
Query: 578 SAVINGEKLLIRMSK--RYKELQLKKPGKAVAAIIQDIHSQRERDMFREADRY---GPER 632
+ NG R K +K P A +++ +R REA + E
Sbjct: 122 ALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKR--VREAQSFISAAIEP 179
Query: 633 PRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPSRADWGNGRDSWEHSPYARREEERDPAP 692
+S + RSHT S S SSS S R+ + S S +++ R +P
Sbjct: 180 ESGKSNERKGGRSRSHTRS-KSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 238
Query: 693 WRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHREKYPRSGSPNLPHSVSSY 752
+ R+R + R+ + ++ E+ REK
Sbjct: 239 HKKRSKS-RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE--------------- 282
Query: 753 KSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLGPKVT 812
+ RE +++ + K K+++ + + KD R RE H D KE +
Sbjct: 283 REREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKE 342
Query: 813 RAPEGAKAKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQEGMEESPQSVGRQEKE 872
R + +K ++ K K++ + + + + E + SP++ +++
Sbjct: 343 REKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK 402
Query: 873 AEFSDPENTRTKKEQDWESESE 894
+ S +R KK++ E E +
Sbjct: 403 SSRSPSPRSRNKKDKKREKERD 424
Score = 47.0 bits (110), Expect = 1e-04
Identities = 60/299 (20%), Positives = 115/299 (38%), Gaps = 16/299 (5%)
Query: 614 HSQRERDMFREADRYGPERPRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPSRADWGNGR 673
HS+R+R + R R RSR R RS +P S SR+ + R
Sbjct: 207 HSRRKRSQSKHRSR-SHNRSRSRQKDRR----RSKSPHKKRSKSRERRKSRSRSHSRDKR 261
Query: 674 -DSWEHSPYARREEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKA---ELDERPEG 729
D+ E R +E+D R+ ++ + + + R+ D+ E D E
Sbjct: 262 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 321
Query: 730 GRPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEAR 789
+ H + + K R K K K + + +A RSR R
Sbjct: 322 EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRER 381
Query: 790 LRESRHPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRD--QEGADDRKENTMA 847
R + K +R+P + +N+K+K + +RD E + + +M
Sbjct: 382 RRRRSRSSSRSPRTSKTIKRKSSRSP--SPRSRNKKDKKREKERDHISERRERERSTSMR 439
Query: 848 ENEAGKEEQEGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNME 906
++ ++ +E +E++ S+ +E E P+++ +K+ D ++ E + + N +
Sbjct: 440 KSSNDRDGKEKLEKNSTSLKEKEHNKE---PDSSVSKEVDDKDAPRTEENKIQHNGNCQ 495
Score = 32.7 bits (73), Expect = 2.2
Identities = 40/170 (23%), Positives = 66/170 (38%), Gaps = 27/170 (15%)
Query: 611 QDIHSQRERDMFREADRYGPERPRSRSPV--------------------SRSLSPRSHTP 650
QD +RE+D +E D + +SR+P SRS S T
Sbjct: 337 QDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTS 396
Query: 651 SFTSCSSSHSPPGPSRADWGNGRDSWEHSPYARREEERDPAPWRDNGD-DKRDRMD--PW 707
SS SP SR R+ RRE ER + + + D D +++++
Sbjct: 397 KTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNST 456
Query: 708 AHDRKHHPRQLDKA---ELDERPEGGRPHREKYPRSGSPNLPHSVSSYKS 754
+ K H ++ D + E+D++ + R K +G+ L S K+
Sbjct: 457 SLKEKEHNKEPDSSVSKEVDDK-DAPRTEENKIQHNGNCQLNEENLSTKT 505
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 53.5 bits (127), Expect = 1e-06
Identities = 112/544 (20%), Positives = 183/544 (33%), Gaps = 54/544 (9%)
Query: 614 HSQRERDMFREADRYGPERPRSRSPVSRSLSPRSHTPS-FTSCSSSHSPPGPSRADWGNG 672
HS+ R R R RSRS RS TP+ S S + + G SR+
Sbjct: 563 HSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPAR 622
Query: 673 RDSWEHSPYARREEERDPA----PWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPE 728
R S SP RR R PA R +R R R+ R A R
Sbjct: 623 RRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSR 682
Query: 729 GGRPHREKYPRSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEA 788
P R RS +P S S R + + P +++ + S RK+++
Sbjct: 683 SRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTP--------QRRGRSGSSSERKNKS 734
Query: 789 RLRESR-HPHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKENT-M 846
R + R + K+ + + +R+ ++K + +R+ +K T
Sbjct: 735 RTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPP 794
Query: 847 AENEAGKEEQEGMEESPQSVGRQEKEAEFSDP-ENTRTKKEQDWESES----------EA 895
+ +G + + +P R+ + + P + ++T Q S S
Sbjct: 795 RRSRSGSSQPKAKSRTPP---RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPR 851
Query: 896 EGESWYPTNMEELVTVDEVGEEEDFIVEPDIPELEEIVPIDQK-DKICPETCLCVTTTLD 954
+G P E+ VT F PD PEL+ P P T
Sbjct: 852 QGSITSPQANEQSVTPQ---RRSCFESSPD-PELKSRTPSRHSCSGSSPPRVKSSTPPRQ 907
Query: 955 LDLAQDFPKEGVKAVGNGAAEISLKSPRELPSASTS--CPSDMDVEMPGLNLDAERKPAE 1012
P+ VKA+ + S PS TS P P N+++ P
Sbjct: 908 SPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRY 967
Query: 1013 SETGLSLEDSDCY-EKEAKGVESSDVHPAPTVQQMSSPKPAEERARQPSPFVDDCKTRGT 1071
S +G S D+ E + S + P P V+ + P P+ ++ P P +
Sbjct: 968 SHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCP-------QEK 1020
Query: 1072 PEDGACEGSPLEEKASPPIETDLQNQACQEVLTPENSRYVEMKSLEVRSPEYTEVELKQP 1131
+D + P +++ TP Y + SL+++ T + +
Sbjct: 1021 SKDSLVQSCPGSLSLCAGVKSS----------TPPGESYFGVSSLQLKGQSQTSPDHRSD 1070
Query: 1132 LSLP 1135
S P
Sbjct: 1071 TSSP 1074
Score = 38.5 bits (88), Expect = 0.040
Identities = 72/318 (22%), Positives = 112/318 (35%), Gaps = 69/318 (21%)
Query: 632 RPRSRSPVSRSLSPRSHTPSFTSCSSSHS--------PPGPSRADWGNGRD---SWEHSP 680
RPRSRSP S L+ + TP S S P R+ G+ ++ SP
Sbjct: 1494 RPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP 1553
Query: 681 YARREEERDP-------APWRDNGD-------DKRDRMDP------WAHDRKHHPRQLDK 720
R E + P P R D + R+ P + + K PR +
Sbjct: 1554 QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPR 1613
Query: 721 AE--LDERPEGGRPHREKYP---RSGSPNL----------------PHSVSSYKSREDGY 759
A+ D PE P P RSGS + H S +R
Sbjct: 1614 AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSR 1673
Query: 760 YRKEPKAK--WDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGLGPKVTRAPEG 817
EPK K + + +P +R+ +R S P+ + P+ R+P
Sbjct: 1674 SSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTP---PRHRRSPSV 1730
Query: 818 AKAKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQEGMEESPQSVGRQEKEAEFSD 877
+ + EK+++ R R + + R + T + G SP+ G Q + S
Sbjct: 1731 SSPEPAEKSRSSR--RRRSASSPRTKTT---------SRRGRSPSPKPRGLQRSRSR-SR 1778
Query: 878 PENTRTKKEQDWESESEA 895
E TRT + +D S++
Sbjct: 1779 REKTRTTRRRDRSGSSQS 1796
Score = 37.7 bits (86), Expect = 0.068
Identities = 50/219 (22%), Positives = 71/219 (32%), Gaps = 15/219 (6%)
Query: 633 PRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPSRADWGNGRDSWEHSPY------ARREE 686
P SP P+S S SS SPP P S SP + RE
Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI 453
Query: 687 ERDP-APWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHREKYPRSGSPNL 745
P + R +G KRD+ R+ + R P + + RS SP
Sbjct: 454 SSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQW 513
Query: 746 PHSVS------SYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPD 799
S S S + G R + W + Q+ RS R+ + R
Sbjct: 514 RRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRS 573
Query: 800 DSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGA 838
S G +R P A+ + + T+R R + A
Sbjct: 574 RSRTPARRGRSRSRTP--ARRRSRSRTPTRRRSRSRTPA 610
Score = 34.7 bits (78), Expect = 0.57
Identities = 49/243 (20%), Positives = 76/243 (31%), Gaps = 8/243 (3%)
Query: 630 PERPRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPSRADWGNGRDSWEHSPYARREEERD 689
P + + +S + S +P +S P P A+ R P A ++
Sbjct: 334 PYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAE----RHGGSPQPLATTPLSQE 389
Query: 690 PAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHREKYPRSGSP-NLPHS 748
P RDR P + ++ + + +P H P S P P S
Sbjct: 390 PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449
Query: 749 VSSYKSREDGYYRKEPKAKWDK-YLKQQQDAPGRSRRKDEARLRESRHPHPDDSGKEDGL 807
S R +AK DK + GRSR A+ SR P G
Sbjct: 450 HREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSR 509
Query: 808 GPKVTRAPEGAK-AKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQ-EGMEESPQS 865
P+ R+ + + + R+ Q R NT + + SP +
Sbjct: 510 SPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPAT 569
Query: 866 VGR 868
GR
Sbjct: 570 RGR 572
Score = 33.1 bits (74), Expect = 1.7
Identities = 52/271 (19%), Positives = 92/271 (33%), Gaps = 30/271 (11%)
Query: 627 RYGPERPRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPS------RADWGNGRDSWEHSP 680
R P R RS S PR+ + + SS P P+ R+ G+ SP
Sbjct: 1590 RLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSP 1649
Query: 681 YARREEERDPA-PWRDNGDDKRDRMDPWAHDR-KHHPRQLDKAELDERPEGGRPHREKYP 738
E P P + + R P + + PR+ E R R
Sbjct: 1650 EGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRS 1709
Query: 739 RSGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGR---SRRKDEARLRESRH 795
S SP +SR +R+ P + ++ + + R S + + R R
Sbjct: 1710 ASSSPET-------RSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRS 1762
Query: 796 PHPDDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDR--DQEGADDRKENTMAENEAGK 853
P P G + +++++ + T+R DR + R++ + + + +
Sbjct: 1763 PSPKPRGLQ----------RSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTR 1812
Query: 854 EEQEGMEESPQSVGRQEKEAEFSDPENTRTK 884
+ G +S RQE S R++
Sbjct: 1813 RRRGGSGYHSRSPARQESSRTSSRRRRGRSR 1843
Score = 32.3 bits (72), Expect = 2.8
Identities = 71/296 (23%), Positives = 101/296 (34%), Gaps = 30/296 (10%)
Query: 2 VLAAAMSQDADPSGPEQPDRVACSVPGARASPAPS---GPRGMQQPPPPPQPPPPPQAGL 58
VL A D GP PD SVP A + + PPP A
Sbjct: 2148 VLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAAR 2207
Query: 59 PQIIQNAAKLLDKNPFSVSNPNPLLP--SPASLQLAQLQAQLTLHRLKLAQTAVTNNTAA 116
+ L+ +N +P S A++ LA + + LA + AA
Sbjct: 2208 MSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADS---RTPAA 2264
Query: 117 ATVLNQVLSKVAMSQPLFNQLRHPSVITGPHGH---AGVPQHAAAIPSTRFPSNAIAFSP 173
A +N + A++ N L P T P + A P AA+ T + A +
Sbjct: 2265 AAAMNLASPRTAVAPSAVN-LADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANY 2323
Query: 174 PSQTRGPGP--SMNLPNQPPSAMVMHPFTGVMPQTPGQPA-----------VILGIGKTG 220
PS +R P S NL P SA P +T A + G T
Sbjct: 2324 PSSSRTPQAPASANLVG-PRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTS 2382
Query: 221 PAPATAGFYEYGKASSGQTYGPETDGQPGFLPSSASTSGSVTYEGHYSHTGQDGQA 276
P + + + SG+T P D P SA + +T E S + + GQA
Sbjct: 2383 PRVPLSAY----ERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQA 2434
Score = 31.6 bits (70), Expect = 4.9
Identities = 52/242 (21%), Positives = 84/242 (34%), Gaps = 36/242 (14%)
Query: 623 READRYGPERPRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPSRADWGNGRDSWEHSPYA 682
REA + PE P+ S V S S RS TP + GR S SP
Sbjct: 158 REAKQPAPEPPKPYSLVRESSSSRSPTPK----------QKKKKKKKDRGRRSESSSP-- 205
Query: 683 RREEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHREKYPRSGS 742
RRE ++ + K+ R + + RKH ++ + + + K RS +
Sbjct: 206 RRERKK-------SSKKKKHRSESESKKRKH------RSPTPKSKRKSKDKKRKRSRSTT 252
Query: 743 PNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHPDDSG 802
P P S +++S + + D + + A ++ A R P P
Sbjct: 253 P-APKSRRAHRSTS-----ADSASSSDTSRSRSRSAAAKTHTTALA----GRSPSPASGR 302
Query: 803 KEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGAD-DRKENTMAENEAGKEEQEGMEE 861
+ +G P + + + TK+ E D D+KE + E E
Sbjct: 303 RGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPE 362
Query: 862 SP 863
P
Sbjct: 363 PP 364
Score = 31.2 bits (69), Expect = 6.3
Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 5/91 (5%)
Query: 4 AAAMSQDADPSGPEQPDRVACSVPGARASPAPSGPRGMQQPPPPPQPPPPPQAG----LP 59
+++ S + S + S + SPA GP+ + +P P +PPP + P
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681
Query: 60 QIIQNAAKLLDKNPFSVSNPNPLLPSPASLQ 90
++ L +P P+P PSP Q
Sbjct: 2682 IDSLRDSRSLSYSPVERRRPSP-QPSPRDQQ 2711
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,602,948
Number of Sequences: 37866
Number of extensions: 3735432
Number of successful extensions: 42504
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 567
Number of HSP's successfully gapped in prelim test: 1130
Number of HSP's that attempted gapping in prelim test: 21784
Number of HSP's gapped (non-prelim): 14204
length of query: 1227
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1113
effective length of database: 13,930,794
effective search space: 15504973722
effective search space used: 15504973722
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.