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Search of human proteins with 195976775
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|195976775 dysferlin isoform 4 [Homo sapiens]
(2098 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|195976775 dysferlin isoform 4 [Homo sapiens] 4323 0.0
gi|195976766 dysferlin isoform 7 [Homo sapiens] 4313 0.0
gi|195976779 dysferlin isoform 1 [Homo sapiens] 4311 0.0
gi|195976762 dysferlin isoform 13 [Homo sapiens] 4273 0.0
gi|195976760 dysferlin isoform 12 [Homo sapiens] 4262 0.0
gi|195976764 dysferlin isoform 14 [Homo sapiens] 4260 0.0
gi|195976777 dysferlin isoform 3 [Homo sapiens] 4242 0.0
gi|195976821 dysferlin isoform 2 [Homo sapiens] 4231 0.0
gi|195976773 dysferlin isoform 5 [Homo sapiens] 4229 0.0
gi|195976769 dysferlin isoform 6 [Homo sapiens] 4219 0.0
gi|195976754 dysferlin isoform 9 [Homo sapiens] 4191 0.0
gi|4503431 dysferlin isoform 8 [Homo sapiens] 4180 0.0
gi|195976756 dysferlin isoform 10 [Homo sapiens] 4179 0.0
gi|195976758 dysferlin isoform 11 [Homo sapiens] 4168 0.0
gi|19718759 myoferlin isoform b [Homo sapiens] 2380 0.0
gi|7305053 myoferlin isoform a [Homo sapiens] 2372 0.0
gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens] 1400 0.0
gi|35493868 otoferlin isoform b [Homo sapiens] 720 0.0
gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens] 714 0.0
gi|35493853 otoferlin isoform c [Homo sapiens] 712 0.0
gi|35493860 otoferlin isoform d [Homo sapiens] 712 0.0
gi|34740331 otoferlin isoform a [Homo sapiens] 712 0.0
gi|119120884 fer-1-like 6 [Homo sapiens] 709 0.0
gi|4759026 RAS protein activator like 1 [Homo sapiens] 65 5e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 54 1e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 54 1e-06
gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo... 54 2e-06
gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom... 54 2e-06
gi|239743309 PREDICTED: similar to calcium-promoted Ras inactiva... 53 3e-06
gi|239743307 PREDICTED: similar to calcium-promoted Ras inactiva... 53 3e-06
>gi|195976775 dysferlin isoform 4 [Homo sapiens]
Length = 2098
Score = 4323 bits (11213), Expect = 0.0
Identities = 2098/2098 (100%), Positives = 2098/2098 (100%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540
Query: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600
INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600
Query: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660
VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660
Query: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720
DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720
Query: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780
EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780
Query: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840
SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840
Query: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900
YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900
Query: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960
ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960
Query: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020
DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020
Query: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080
LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080
Query: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140
EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140
Query: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200
KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200
Query: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260
HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260
Query: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320
CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320
Query: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380
EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380
Query: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440
GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440
Query: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF 1500
RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF
Sbjct: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF 1500
Query: 1501 ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI 1560
ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI
Sbjct: 1501 ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI 1560
Query: 1561 GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY 1620
GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY
Sbjct: 1561 GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY 1620
Query: 1621 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1680
IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET
Sbjct: 1621 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1680
Query: 1681 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM 1740
VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM
Sbjct: 1681 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM 1740
Query: 1741 FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK 1800
FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK
Sbjct: 1741 FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK 1800
Query: 1801 LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG 1860
LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG
Sbjct: 1801 LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG 1860
Query: 1861 WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI 1920
WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI
Sbjct: 1861 WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI 1920
Query: 1921 PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ 1980
PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ
Sbjct: 1921 PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ 1980
Query: 1981 KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD 2040
KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD
Sbjct: 1981 KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD 2040
Query: 2041 TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2098
TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2041 TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2098
>gi|195976766 dysferlin isoform 7 [Homo sapiens]
Length = 2112
Score = 4313 bits (11185), Expect = 0.0
Identities = 2097/2112 (99%), Positives = 2098/2112 (99%), Gaps = 14/2112 (0%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 526
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
Query: 527 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 586
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 541 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
Query: 587 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 646
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 601 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
Query: 647 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 706
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 661 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
Query: 707 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 721 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
Query: 767 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 781 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
Query: 827 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 841 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
Query: 887 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 946
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 901 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
Query: 947 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1006
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 961 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
Query: 1007 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1066
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
Query: 1067 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1126
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
Query: 1127 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1186
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
Query: 1187 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1246
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
Query: 1247 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1306
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
Query: 1307 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1366
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
Query: 1367 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1426
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
Query: 1427 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1486
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
Query: 1487 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1546
IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1501 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1560
Query: 1547 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1606
RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1561 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1620
Query: 1607 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1666
GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1621 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1680
Query: 1667 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1726
DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1681 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1740
Query: 1727 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1786
HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1741 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1800
Query: 1787 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1846
PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1801 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1860
Query: 1847 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1906
SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1861 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1920
Query: 1907 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1966
KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1921 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1980
Query: 1967 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2026
DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1981 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2040
Query: 2027 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2086
PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2041 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2100
Query: 2087 NYAAMKLVKPFS 2098
NYAAMKLVKPFS
Sbjct: 2101 NYAAMKLVKPFS 2112
>gi|195976779 dysferlin isoform 1 [Homo sapiens]
Length = 2119
Score = 4311 bits (11181), Expect = 0.0
Identities = 2098/2119 (99%), Positives = 2098/2119 (99%), Gaps = 21/2119 (0%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540
Query: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600
INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600
Query: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660
VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660
Query: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720
DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720
Query: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780
EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780
Query: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840
SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840
Query: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900
YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900
Query: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960
ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960
Query: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020
DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020
Query: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080
LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080
Query: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140
EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140
Query: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200
KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200
Query: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260
HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260
Query: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320
CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320
Query: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380
EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380
Query: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440
GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440
Query: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ------------ 1488
RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ
Sbjct: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1500
Query: 1489 ---------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1539
EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF
Sbjct: 1501 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1560
Query: 1540 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1599
CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR
Sbjct: 1561 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1620
Query: 1600 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1659
IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK
Sbjct: 1621 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1680
Query: 1660 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1719
DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL
Sbjct: 1681 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1740
Query: 1720 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1779
LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV
Sbjct: 1741 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1800
Query: 1780 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1839
PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR
Sbjct: 1801 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1860
Query: 1840 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1899
DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE
Sbjct: 1861 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1920
Query: 1900 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1959
QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK
Sbjct: 1921 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1980
Query: 1960 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2019
CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP
Sbjct: 1981 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2040
Query: 2020 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2079
AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA
Sbjct: 2041 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2100
Query: 2080 IFIYAFPNYAAMKLVKPFS 2098
IFIYAFPNYAAMKLVKPFS
Sbjct: 2101 IFIYAFPNYAAMKLVKPFS 2119
>gi|195976762 dysferlin isoform 13 [Homo sapiens]
Length = 2097
Score = 4273 bits (11081), Expect = 0.0
Identities = 2077/2098 (98%), Positives = 2081/2098 (99%), Gaps = 1/2098 (0%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 539
Query: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600
INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 540 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 599
Query: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660
VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 600 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 659
Query: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720
DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 660 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 719
Query: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780
EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 720 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 779
Query: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840
SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 780 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 839
Query: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900
YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 840 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 899
Query: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960
ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 900 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 959
Query: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020
DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 960 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1019
Query: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080
LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 1020 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1079
Query: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140
EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1080 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1139
Query: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200
KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1140 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1199
Query: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260
HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1200 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1259
Query: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320
CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1260 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1319
Query: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380
EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1320 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1379
Query: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440
GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1380 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1439
Query: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF 1500
RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF
Sbjct: 1440 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF 1499
Query: 1501 ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI 1560
ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI
Sbjct: 1500 ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI 1559
Query: 1561 GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY 1620
GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY
Sbjct: 1560 GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY 1619
Query: 1621 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1680
IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET
Sbjct: 1620 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1679
Query: 1681 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM 1740
VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM
Sbjct: 1680 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM 1739
Query: 1741 FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK 1800
FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK
Sbjct: 1740 FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK 1799
Query: 1801 LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG 1860
LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG
Sbjct: 1800 LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG 1859
Query: 1861 WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI 1920
WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI
Sbjct: 1860 WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI 1919
Query: 1921 PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ 1980
PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ
Sbjct: 1920 PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ 1979
Query: 1981 KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD 2040
KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD
Sbjct: 1980 KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD 2039
Query: 2041 TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2098
TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2040 TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2097
>gi|195976760 dysferlin isoform 12 [Homo sapiens]
Length = 2111
Score = 4262 bits (11053), Expect = 0.0
Identities = 2076/2112 (98%), Positives = 2081/2112 (98%), Gaps = 15/2112 (0%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 526
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 539
Query: 527 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 586
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 540 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 599
Query: 587 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 646
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 600 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 659
Query: 647 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 706
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 660 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 719
Query: 707 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 720 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 779
Query: 767 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 780 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 839
Query: 827 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 840 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 899
Query: 887 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 946
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 900 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 959
Query: 947 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1006
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 960 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1019
Query: 1007 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1066
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1020 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1079
Query: 1067 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1126
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1080 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1139
Query: 1127 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1186
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1140 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1199
Query: 1187 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1246
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1200 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1259
Query: 1247 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1306
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1260 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1319
Query: 1307 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1366
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1320 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1379
Query: 1367 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1426
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1380 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1439
Query: 1427 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1486
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1440 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1499
Query: 1487 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1546
IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1500 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1559
Query: 1547 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1606
RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1560 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1619
Query: 1607 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1666
GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1620 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1679
Query: 1667 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1726
DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1680 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1739
Query: 1727 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1786
HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1740 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1799
Query: 1787 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1846
PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1800 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1859
Query: 1847 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1906
SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1860 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1919
Query: 1907 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1966
KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1920 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1979
Query: 1967 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2026
DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1980 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2039
Query: 2027 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2086
PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2040 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2099
Query: 2087 NYAAMKLVKPFS 2098
NYAAMKLVKPFS
Sbjct: 2100 NYAAMKLVKPFS 2111
>gi|195976764 dysferlin isoform 14 [Homo sapiens]
Length = 2118
Score = 4260 bits (11049), Expect = 0.0
Identities = 2077/2119 (98%), Positives = 2081/2119 (98%), Gaps = 22/2119 (1%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 539
Query: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600
INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 540 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 599
Query: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660
VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 600 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 659
Query: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720
DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 660 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 719
Query: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780
EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 720 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 779
Query: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840
SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 780 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 839
Query: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900
YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 840 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 899
Query: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960
ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 900 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 959
Query: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020
DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 960 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1019
Query: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080
LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 1020 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1079
Query: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140
EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1080 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1139
Query: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200
KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1140 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1199
Query: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260
HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1200 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1259
Query: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320
CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1260 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1319
Query: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380
EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1320 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1379
Query: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440
GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1380 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1439
Query: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ------------ 1488
RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ
Sbjct: 1440 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1499
Query: 1489 ---------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1539
EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF
Sbjct: 1500 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1559
Query: 1540 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1599
CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR
Sbjct: 1560 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1619
Query: 1600 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1659
IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK
Sbjct: 1620 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1679
Query: 1660 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1719
DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL
Sbjct: 1680 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1739
Query: 1720 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1779
LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV
Sbjct: 1740 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1799
Query: 1780 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1839
PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR
Sbjct: 1800 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1859
Query: 1840 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1899
DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE
Sbjct: 1860 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1919
Query: 1900 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1959
QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK
Sbjct: 1920 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1979
Query: 1960 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2019
CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP
Sbjct: 1980 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2039
Query: 2020 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2079
AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA
Sbjct: 2040 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2099
Query: 2080 IFIYAFPNYAAMKLVKPFS 2098
IFIYAFPNYAAMKLVKPFS
Sbjct: 2100 IFIYAFPNYAAMKLVKPFS 2118
>gi|195976777 dysferlin isoform 3 [Homo sapiens]
Length = 2067
Score = 4242 bits (11001), Expect = 0.0
Identities = 2067/2098 (98%), Positives = 2067/2098 (98%), Gaps = 31/2098 (1%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 509
Query: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600
INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 510 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 569
Query: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660
VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 570 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 629
Query: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720
DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 630 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 689
Query: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780
EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 690 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 749
Query: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840
SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 750 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 809
Query: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900
YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 810 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 869
Query: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960
ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 870 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 929
Query: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020
DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 930 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 989
Query: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080
LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 990 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1049
Query: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140
EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1050 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1109
Query: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200
KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1110 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1169
Query: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260
HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1170 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1229
Query: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320
CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1230 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1289
Query: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380
EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1290 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1349
Query: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440
GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1350 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1409
Query: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF 1500
RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF
Sbjct: 1410 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF 1469
Query: 1501 ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI 1560
ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI
Sbjct: 1470 ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI 1529
Query: 1561 GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY 1620
GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY
Sbjct: 1530 GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY 1589
Query: 1621 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1680
IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET
Sbjct: 1590 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1649
Query: 1681 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM 1740
VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM
Sbjct: 1650 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM 1709
Query: 1741 FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK 1800
FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK
Sbjct: 1710 FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK 1769
Query: 1801 LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG 1860
LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG
Sbjct: 1770 LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG 1829
Query: 1861 WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI 1920
WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI
Sbjct: 1830 WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI 1889
Query: 1921 PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ 1980
PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ
Sbjct: 1890 PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ 1949
Query: 1981 KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD 2040
KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD
Sbjct: 1950 KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD 2009
Query: 2041 TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2098
TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2010 TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2067
>gi|195976821 dysferlin isoform 2 [Homo sapiens]
Length = 2081
Score = 4231 bits (10973), Expect = 0.0
Identities = 2066/2112 (97%), Positives = 2067/2112 (97%), Gaps = 45/2112 (2%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 526
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 509
Query: 527 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 586
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 510 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 569
Query: 587 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 646
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 570 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 629
Query: 647 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 706
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 630 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 689
Query: 707 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 690 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 749
Query: 767 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 750 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 809
Query: 827 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 810 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 869
Query: 887 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 946
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 870 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 929
Query: 947 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1006
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 930 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 989
Query: 1007 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1066
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 990 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1049
Query: 1067 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1126
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1050 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1109
Query: 1127 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1186
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1110 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1169
Query: 1187 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1246
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1170 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1229
Query: 1247 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1306
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1230 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1289
Query: 1307 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1366
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1290 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1349
Query: 1367 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1426
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1350 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1409
Query: 1427 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1486
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1410 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1469
Query: 1487 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1546
IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1470 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1529
Query: 1547 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1606
RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1530 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1589
Query: 1607 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1666
GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1590 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1649
Query: 1667 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1726
DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1650 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1709
Query: 1727 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1786
HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1710 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1769
Query: 1787 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1846
PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1770 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1829
Query: 1847 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1906
SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1830 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1889
Query: 1907 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1966
KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1890 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1949
Query: 1967 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2026
DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1950 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2009
Query: 2027 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2086
PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2010 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2069
Query: 2087 NYAAMKLVKPFS 2098
NYAAMKLVKPFS
Sbjct: 2070 NYAAMKLVKPFS 2081
>gi|195976773 dysferlin isoform 5 [Homo sapiens]
Length = 2088
Score = 4229 bits (10969), Expect = 0.0
Identities = 2067/2119 (97%), Positives = 2067/2119 (97%), Gaps = 52/2119 (2%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 509
Query: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600
INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 510 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 569
Query: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660
VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 570 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 629
Query: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720
DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 630 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 689
Query: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780
EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 690 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 749
Query: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840
SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 750 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 809
Query: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900
YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 810 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 869
Query: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960
ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 870 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 929
Query: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020
DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 930 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 989
Query: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080
LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 990 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1049
Query: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140
EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1050 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1109
Query: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200
KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1110 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1169
Query: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260
HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1170 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1229
Query: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320
CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1230 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1289
Query: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380
EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1290 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1349
Query: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440
GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1350 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1409
Query: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ------------ 1488
RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ
Sbjct: 1410 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1469
Query: 1489 ---------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1539
EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF
Sbjct: 1470 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1529
Query: 1540 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1599
CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR
Sbjct: 1530 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1589
Query: 1600 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1659
IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK
Sbjct: 1590 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1649
Query: 1660 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1719
DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL
Sbjct: 1650 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1709
Query: 1720 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1779
LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV
Sbjct: 1710 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1769
Query: 1780 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1839
PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR
Sbjct: 1770 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1829
Query: 1840 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1899
DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE
Sbjct: 1830 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1889
Query: 1900 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1959
QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK
Sbjct: 1890 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1949
Query: 1960 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2019
CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP
Sbjct: 1950 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2009
Query: 2020 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2079
AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA
Sbjct: 2010 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2069
Query: 2080 IFIYAFPNYAAMKLVKPFS 2098
IFIYAFPNYAAMKLVKPFS
Sbjct: 2070 IFIYAFPNYAAMKLVKPFS 2088
>gi|195976769 dysferlin isoform 6 [Homo sapiens]
Length = 2102
Score = 4219 bits (10941), Expect = 0.0
Identities = 2066/2133 (96%), Positives = 2067/2133 (96%), Gaps = 66/2133 (3%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 526
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 509
Query: 527 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 586
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 510 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 569
Query: 587 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 646
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 570 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 629
Query: 647 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 706
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 630 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 689
Query: 707 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 690 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 749
Query: 767 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 750 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 809
Query: 827 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 810 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 869
Query: 887 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 946
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 870 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 929
Query: 947 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1006
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 930 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 989
Query: 1007 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1066
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 990 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1049
Query: 1067 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1126
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1050 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1109
Query: 1127 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1186
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1110 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1169
Query: 1187 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1246
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1170 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1229
Query: 1247 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1306
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1230 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1289
Query: 1307 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1366
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1290 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1349
Query: 1367 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1426
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1350 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1409
Query: 1427 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1486
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1410 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1469
Query: 1487 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1525
IQ EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1470 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1529
Query: 1526 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1585
QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1530 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1589
Query: 1586 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1645
HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1590 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1649
Query: 1646 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1705
GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1650 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1709
Query: 1706 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1765
GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1710 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1769
Query: 1766 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1825
ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1770 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1829
Query: 1826 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1885
ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1830 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1889
Query: 1886 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1945
NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1890 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1949
Query: 1946 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2005
DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1950 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2009
Query: 2006 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2065
TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2010 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2069
Query: 2066 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2098
ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2070 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2102
>gi|195976754 dysferlin isoform 9 [Homo sapiens]
Length = 2066
Score = 4191 bits (10869), Expect = 0.0
Identities = 2046/2098 (97%), Positives = 2050/2098 (97%), Gaps = 32/2098 (1%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 153 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 209 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 269 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 329 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 389 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 449 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 508
Query: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600
INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 509 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 568
Query: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660
VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 569 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 628
Query: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720
DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 629 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 688
Query: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780
EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 689 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 748
Query: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840
SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 749 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 808
Query: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900
YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 809 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 868
Query: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960
ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 869 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 928
Query: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020
DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 929 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 988
Query: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080
LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 989 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1048
Query: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140
EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1049 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1108
Query: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200
KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1109 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1168
Query: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260
HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1169 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1228
Query: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320
CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1229 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1288
Query: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380
EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1289 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1348
Query: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440
GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1349 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1408
Query: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF 1500
RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF
Sbjct: 1409 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF 1468
Query: 1501 ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI 1560
ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI
Sbjct: 1469 ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI 1528
Query: 1561 GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY 1620
GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY
Sbjct: 1529 GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY 1588
Query: 1621 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1680
IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET
Sbjct: 1589 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1648
Query: 1681 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM 1740
VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM
Sbjct: 1649 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM 1708
Query: 1741 FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK 1800
FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK
Sbjct: 1709 FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK 1768
Query: 1801 LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG 1860
LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG
Sbjct: 1769 LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG 1828
Query: 1861 WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI 1920
WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI
Sbjct: 1829 WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI 1888
Query: 1921 PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ 1980
PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ
Sbjct: 1889 PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ 1948
Query: 1981 KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD 2040
KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD
Sbjct: 1949 KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD 2008
Query: 2041 TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2098
TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2009 TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2066
>gi|4503431 dysferlin isoform 8 [Homo sapiens]
Length = 2080
Score = 4180 bits (10841), Expect = 0.0
Identities = 2045/2112 (96%), Positives = 2050/2112 (97%), Gaps = 46/2112 (2%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 153 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 209 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 269 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 329 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 389 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 526
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 449 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 508
Query: 527 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 586
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 509 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 568
Query: 587 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 646
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 569 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 628
Query: 647 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 706
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 629 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 688
Query: 707 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 689 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 748
Query: 767 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 749 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 808
Query: 827 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 809 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 868
Query: 887 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 946
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 869 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 928
Query: 947 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1006
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 929 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 988
Query: 1007 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1066
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 989 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1048
Query: 1067 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1126
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1049 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1108
Query: 1127 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1186
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1109 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1168
Query: 1187 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1246
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1169 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1228
Query: 1247 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1306
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1229 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1288
Query: 1307 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1366
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1289 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1348
Query: 1367 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1426
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1349 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1408
Query: 1427 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1486
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1409 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1468
Query: 1487 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1546
IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1469 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1528
Query: 1547 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1606
RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1529 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1588
Query: 1607 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1666
GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1589 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1648
Query: 1667 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1726
DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1649 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1708
Query: 1727 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1786
HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1709 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1768
Query: 1787 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1846
PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1769 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1828
Query: 1847 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1906
SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1829 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1888
Query: 1907 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1966
KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1889 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1948
Query: 1967 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2026
DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1949 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2008
Query: 2027 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2086
PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2009 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2068
Query: 2087 NYAAMKLVKPFS 2098
NYAAMKLVKPFS
Sbjct: 2069 NYAAMKLVKPFS 2080
>gi|195976756 dysferlin isoform 10 [Homo sapiens]
Length = 2087
Score = 4179 bits (10837), Expect = 0.0
Identities = 2046/2119 (96%), Positives = 2050/2119 (96%), Gaps = 53/2119 (2%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 153 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 209 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 269 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 329 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 389 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 449 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 508
Query: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600
INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 509 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 568
Query: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660
VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 569 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 628
Query: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720
DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 629 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 688
Query: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780
EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 689 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 748
Query: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840
SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 749 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 808
Query: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900
YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 809 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 868
Query: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960
ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 869 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 928
Query: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020
DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 929 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 988
Query: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080
LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 989 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1048
Query: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140
EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1049 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1108
Query: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200
KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1109 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1168
Query: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260
HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1169 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1228
Query: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320
CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1229 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1288
Query: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380
EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1289 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1348
Query: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440
GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1349 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1408
Query: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ------------ 1488
RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ
Sbjct: 1409 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1468
Query: 1489 ---------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1539
EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF
Sbjct: 1469 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1528
Query: 1540 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1599
CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR
Sbjct: 1529 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1588
Query: 1600 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1659
IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK
Sbjct: 1589 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1648
Query: 1660 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1719
DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL
Sbjct: 1649 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1708
Query: 1720 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1779
LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV
Sbjct: 1709 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1768
Query: 1780 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1839
PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR
Sbjct: 1769 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1828
Query: 1840 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1899
DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE
Sbjct: 1829 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1888
Query: 1900 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1959
QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK
Sbjct: 1889 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1948
Query: 1960 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2019
CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP
Sbjct: 1949 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2008
Query: 2020 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2079
AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA
Sbjct: 2009 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2068
Query: 2080 IFIYAFPNYAAMKLVKPFS 2098
IFIYAFPNYAAMKLVKPFS
Sbjct: 2069 IFIYAFPNYAAMKLVKPFS 2087
>gi|195976758 dysferlin isoform 11 [Homo sapiens]
Length = 2101
Score = 4168 bits (10809), Expect = 0.0
Identities = 2045/2133 (95%), Positives = 2050/2133 (96%), Gaps = 67/2133 (3%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152
Query: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 153 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208
Query: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 209 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268
Query: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 269 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328
Query: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 329 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388
Query: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 389 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448
Query: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 526
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 449 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 508
Query: 527 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 586
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 509 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 568
Query: 587 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 646
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 569 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 628
Query: 647 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 706
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 629 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 688
Query: 707 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 689 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 748
Query: 767 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 749 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 808
Query: 827 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 809 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 868
Query: 887 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 946
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 869 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 928
Query: 947 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1006
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 929 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 988
Query: 1007 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1066
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 989 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1048
Query: 1067 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1126
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1049 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1108
Query: 1127 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1186
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1109 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1168
Query: 1187 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1246
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1169 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1228
Query: 1247 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1306
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1229 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1288
Query: 1307 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1366
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1289 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1348
Query: 1367 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1426
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1349 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1408
Query: 1427 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1486
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1409 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1468
Query: 1487 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1525
IQ EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1469 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1528
Query: 1526 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1585
QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1529 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1588
Query: 1586 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1645
HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1589 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1648
Query: 1646 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1705
GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1649 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1708
Query: 1706 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1765
GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1709 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1768
Query: 1766 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1825
ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1769 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1828
Query: 1826 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1885
ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1829 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1888
Query: 1886 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1945
NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1889 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1948
Query: 1946 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2005
DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1949 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2008
Query: 2006 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2065
TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2009 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2068
Query: 2066 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2098
ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2069 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2101
>gi|19718759 myoferlin isoform b [Homo sapiens]
Length = 2048
Score = 2380 bits (6167), Expect = 0.0
Identities = 1180/2127 (55%), Positives = 1519/2127 (71%), Gaps = 112/2127 (5%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ ASN+P K + DP+ S+ F+ KK+TK + N +NPVWNE E+DL+GIPL
Sbjct: 1 MLRVIVESASNIPKTKFGK-PDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLV 119
D S L ++VKD ET+G+N+ +G A V L+++ S S + LL+ K Q TGA++
Sbjct: 60 DFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATID 119
Query: 120 LQVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKK 179
L + Y P P P P L P++P + GG +
Sbjct: 120 LVIGYDP-----PSAPHPNDLS-GPSVPGM-----GGDGEEDE----------------- 151
Query: 180 WPAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAP 239
G+ED D + G + GP + +L +R
Sbjct: 152 --------GDEDRLDNAVRGPGPK-------GPVGTVSEAQLA----------RRLTKVK 186
Query: 240 TSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLF 299
SR++LS+KPQDFQIRV+VIEGRQL G NI+PVVKV GQT RTRI +GN+P F+E F
Sbjct: 187 NSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRPVVKVHVCGQTHRTRIKRGNNPFFDELFF 246
Query: 300 FNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPD 359
+N+ +P EL DE I I V +S SLR D L+GEF++DVG +Y EP HA +RKWLLL+DP+
Sbjct: 247 YNVNMTPSELMDEIISIRVYNSHSLRADCLMGEFKIDVGFVYDEPGHAVMRKWLLLNDPE 306
Query: 360 DFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFR 419
D S+G++GY+K S+ VLG GDE P ER+D D +D+ESNLL P G+ALR F LK++R
Sbjct: 307 DTSSGSKGYMKVSMFVLGTGDEPPPERRDRDNDSDDVESNLLLPAGIALRWVTFLLKIYR 366
Query: 420 AEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT 479
AED+PQMDDA VK+IFG ++KKNLVDPFVEVSFAGK +C+ I+EK ANP+WNQ +
Sbjct: 367 AEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPEWNQVVN 426
Query: 480 LPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEV---DDYLGFLPTF 536
L FPS+CEK+++ I DWDRLT ND+V TTYL +SKI+A GGE+EV + +GF+PTF
Sbjct: 427 LQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASGGEVEVNTGETEVGFVPTF 486
Query: 537 GPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVE-HSEQKVEDLPA 595
GPCY+NLYGSPRE+TGFPDPY ELNTGKGEGVAYRGR+L+ L T L + ++K+E +
Sbjct: 487 GPCYLNLYGSPREYTGFPDPYDELNTGKGEGVAYRGRILVELATFLEKTPPDKKLEPISN 546
Query: 596 DDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQY 655
DD+L VEKY RRRKYSL A F+SATMLQDV +AIQFEVSIGNYGNKFD TC PLASTTQY
Sbjct: 547 DDLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNKFDTTCKPLASTTQY 606
Query: 656 SRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALK 715
SRAVFDG +YYYLPW + KPVV L+SYWEDISHR++ N LL +A+RL+ +E + ++
Sbjct: 607 SRAVFDGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTLLAMAERLQTNIEALKSGIQ 666
Query: 716 AQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALA 775
+ + L +L DE+I L + T LD + +LR+ LSQI EAA+
Sbjct: 667 GKIPANQLAELWLKLIDEVIEDTRYTLPLTEGKANVTVLDTQIRKLRSRSLSQIHEAAVR 726
Query: 776 LKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFS 835
++ +++ + L + EDWL +L L EEPQNS+PDI+IWM++G+KR+AY R+PAHQVL+S
Sbjct: 727 MRSEATDVKSTLAEIEDWLDKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYS 786
Query: 836 RRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSV 895
G N GK CGK QTIFLKYP EK G ++PV++RV +W GLS EK+FN FAEG +V
Sbjct: 787 TSGENASGKYCGKTQTIFLKYPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTV 846
Query: 896 FAETYENETKLALVGNWGTTGLT-YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEK 954
FAE YEN+ + G WGT+GL KFSDVTGKIKL ++ F P GW W G+W V PE+
Sbjct: 847 FAEMYENQA--LMFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGEWIVDPER 904
Query: 955 TLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWED 1014
+LL + DAGH F +EV++N++R PGG W D YTD NG+K ++ CP GW+WED
Sbjct: 905 SLLTEADAGHTEFTDEVYQNESRYPGGDWKPAEDTYTDANGDKAASPSELTCPPGWEWED 964
Query: 1015 EEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEAL 1074
+ WS D+NRAVDE+GWEY ITIPP+ KPK WV AEKMY+THRRRR VR R++DL+Q +
Sbjct: 965 DAWSYDINRAVDEKGWEYGITIPPDHKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASS 1024
Query: 1075 KRHRQAEAEG-EGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGA 1133
E + EGWEYASL GWKFH + R +D FRRRRWRR+M P E G AA+F LEGA
Sbjct: 1025 TARAMEELQDQEGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGA 1084
Query: 1134 LGGVM----DDKS-EDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKD 1188
LG D+KS E +T FG N P +SC FD YHLRCY+YQAR+L A+DKD
Sbjct: 1085 LGADTTEDGDEKSLEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCYVYQARNLLALDKD 1144
Query: 1189 SFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYD 1248
SFSDPYA + FLH+S+ T ++ +TLNPTWDQT+IF E+EI+GEP TV + PP +++EL+D
Sbjct: 1145 SFSDPYAHICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPKVIMELFD 1204
Query: 1249 HDTYGADEFMGRCICQP------SLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAI 1302
+D G DEF+GR I P ++ P+L W P+ G + G++L + ELI R K
Sbjct: 1205 NDQVGKDEFLGRSIFSPVVKLNSEMDITPKLLWHPVMNGDKACGDVLVTAELILRGK--- 1261
Query: 1303 HHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNM 1362
+ ++LP PPQR N+YMVPQ I+P +Q TAIEILAWGLRNM
Sbjct: 1262 ------------------DGSNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNM 1303
Query: 1363 KSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVK 1422
K++Q+A+I+SPSLVVECGG+ V+S VI+NL+K PNF LFM+V LP+EELY PP+ +K
Sbjct: 1304 KNFQMASITSPSLVVECGGERVESVVIKNLKKTPNFPSSVLFMKVFLPKEELYMPPLVIK 1363
Query: 1423 VIDNRQFGRRPVVGQCTIRSLESFLCDPYSA-ESPSPQGGPDDVSLLS--PGEDVLIDID 1479
VID+RQFGR+PVVGQCTI L+ F CDPY+ E PQ SLLS P D++I+++
Sbjct: 1364 VIDHRQFGRKPVVGQCTIERLDRFRCDPYAGKEDIVPQ---LKASLLSAPPCRDIVIEME 1420
Query: 1480 DKEPLIPI----QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEG 1535
D +PL+ +EEE +DWWSKF+AS GE EKCG Y++K + LK+Y+ +LENV FEG
Sbjct: 1421 DTKPLLASKLTEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEG 1480
Query: 1536 LSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQE 1595
L+DF +TFKLYRGK+ +E EDPSV+GEFKG F+IYPLP+DP++P PPRQF +L PQE
Sbjct: 1481 LTDFSDTFKLYRGKS-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQE 1539
Query: 1596 CLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL 1655
C VRIYIVR LQP+D NG CDPYIKI++GKK + D+D+YIP TL PVFG+M+EL+C L
Sbjct: 1540 CTVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYL 1599
Query: 1656 PLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLR 1715
P EKDLKI++YDYD ++DEK+GET++DLENR LS+FG+ CG+P+ YCVSG N WRDQLR
Sbjct: 1600 PQEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLR 1659
Query: 1716 PSQLLHLFCQQHRVKAPVYRTD--RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVL 1773
P+QLL + P+ D R+ + ++YS++E EA +I + HLG EERLALH+L
Sbjct: 1660 PTQLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHIL 1719
Query: 1774 QQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRC 1833
+ QGLVPEHVE+R L+S QP+I QGKLQMWVD+FPK+LG PGPPFNITPR+A++++LR
Sbjct: 1720 RTQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRV 1779
Query: 1834 IIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPF 1893
IIWNT+DVILD+ S+TGE+MSDIYVKGW+ G EE+KQKTDVHYRSL GEGNFNWRF+FPF
Sbjct: 1780 IIWNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPF 1839
Query: 1894 DYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKP 1953
DYLPAEQ+C +AKK+ FW +D+TE +IP R++ QIWDNDKFS DD+LG L+LDL P
Sbjct: 1840 DYLPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIP 1899
Query: 1954 AKTAKKCSLDQLDD--AFHP--EWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEI 2009
AK+ +KC LD + D A +P SLFEQK++KGWWPC AE+ +++AGK+EMTLEI
Sbjct: 1900 AKSPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEI 1959
Query: 2010 VAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFI 2069
+ E E +ERPAG+GRDEPNMNPKL+ P RP+TSFLWFT+P KTMKFI+WRRF+W II +
Sbjct: 1960 LNEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLL 2019
Query: 2070 ILFILLLFLAIFIYAFPNYAAMKLVKP 2096
L ILLLF+A+ +Y+ PNY +MK+VKP
Sbjct: 2020 FLLILLLFVAVLLYSLPNYLSMKIVKP 2046
>gi|7305053 myoferlin isoform a [Homo sapiens]
Length = 2061
Score = 2372 bits (6147), Expect = 0.0
Identities = 1179/2140 (55%), Positives = 1518/2140 (70%), Gaps = 125/2140 (5%)
Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
ML ++ ASN+P K + DP+ S+ F+ KK+TK + N +NPVWNE E+DL+GIPL
Sbjct: 1 MLRVIVESASNIPKTKFGK-PDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPL 59
Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLV 119
D S L ++VKD ET+G+N+ +G A V L+++ S S + LL+ K Q TGA++
Sbjct: 60 DFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATID 119
Query: 120 LQVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKK 179
L + Y P P P P L P++P + GG +
Sbjct: 120 LVIGYDP-----PSAPHPNDLS-GPSVPGM-----GGDGEEDE----------------- 151
Query: 180 WPAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAP 239
G+ED D + G + GP + +L +R
Sbjct: 152 --------GDEDRLDNAVRGPGPK-------GPVGTVSEAQLA----------RRLTKVK 186
Query: 240 TSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLF 299
SR++LS+KPQDFQIRV+VIEGRQL G NI+PVVKV GQT RTRI +GN+P F+E F
Sbjct: 187 NSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRPVVKVHVCGQTHRTRIKRGNNPFFDELFF 246
Query: 300 FNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPD 359
+N+ +P EL DE I I V +S SLR D L+GEF++DVG +Y EP HA +RKWLLL+DP+
Sbjct: 247 YNVNMTPSELMDEIISIRVYNSHSLRADCLMGEFKIDVGFVYDEPGHAVMRKWLLLNDPE 306
Query: 360 DFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFR 419
D S+G++GY+K S+ VLG GDE P ER+D D +D+ESNLL P G+ALR F LK++R
Sbjct: 307 DTSSGSKGYMKVSMFVLGTGDEPPPERRDRDNDSDDVESNLLLPAGIALRWVTFLLKIYR 366
Query: 420 AEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT 479
AED+PQMDDA VK+IFG ++KKNLVDPFVEVSFAGK +C+ I+EK ANP+WNQ +
Sbjct: 367 AEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPEWNQVVN 426
Query: 480 LPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE-------------- 525
L FPS+CEK+++ I DWDRLT ND+V TTYL +SKI+A GGE+E
Sbjct: 427 LQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASGGEVEDFSSSGTGAASYTV 486
Query: 526 --VDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLV 583
+ +GF+PTFGPCY+NLYGSPRE+TGFPDPY ELNTGKGEGVAYRGR+L+ L T L
Sbjct: 487 NTGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNTGKGEGVAYRGRILVELATFLE 546
Query: 584 E-HSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKF 642
+ ++K+E + DD+L VEKY RRRKYSL A F+SATMLQDV +AIQFEVSIGNYGNKF
Sbjct: 547 KTPPDKKLEPISNDDLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNKF 606
Query: 643 DMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADR 702
D TC PLASTTQYSRAVFDG +YYYLPW + KPVV L+SYWEDISHR++ N LL +A+R
Sbjct: 607 DTTCKPLASTTQYSRAVFDGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTLLAMAER 666
Query: 703 LEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLR 762
L+ +E + ++ + + L +L DE+I L + T LD + +LR
Sbjct: 667 LQTNIEALKSGIQGKIPANQLAELWLKLIDEVIEDTRYTLPLTEGKANVTVLDTQIRKLR 726
Query: 763 THHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRV 822
+ LSQI EAA+ ++ +++ + L + EDWL +L L EEPQNS+PDI+IWM++G+KR+
Sbjct: 727 SRSLSQIHEAAVRMRSEATDVKSTLAEIEDWLDKLMQLTEEPQNSMPDIIIWMIRGEKRL 786
Query: 823 AYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDE 882
AY R+PAHQVL+S G N GK CGK QTIFLKYP EK G ++PV++RV +W GLS E
Sbjct: 787 AYARIPAHQVLYSTSGENASGKYCGKTQTIFLKYPQEKNNGPKVPVELRVNIWLGLSAVE 846
Query: 883 KEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT-YPKFSDVTGKIKLPKDSFRPSAG 941
K+FN FAEG +VFAE YEN+ + G WGT+GL KFSDVTGKIKL ++ F P G
Sbjct: 847 KKFNSFAEGTFTVFAEMYENQA--LMFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKG 904
Query: 942 WTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPK 1001
W W G+W V PE++LL + DAGH F +EV++N++R PGG W D YTD NG+K
Sbjct: 905 WEWEGEWIVDPERSLLTEADAGHTEFTDEVYQNESRYPGGDWKPAEDTYTDANGDKAASP 964
Query: 1002 DDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWV 1061
++ CP GW+WED+ WS D+NRAVDE+GWEY ITIPP+ KPK WV AEKMY+THRRRR V
Sbjct: 965 SELTCPPGWEWEDDAWSYDINRAVDEKGWEYGITIPPDHKPKSWVAAEKMYHTHRRRRLV 1024
Query: 1062 RLRRRDLSQMEALKRHRQAEAEG-EGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLE 1120
R R++DL+Q + E + EGWEYASL GWKFH + R +D FRRRRWRR+M P E
Sbjct: 1025 RKRKKDLTQTASSTARAMEELQDQEGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSE 1084
Query: 1121 KTGPAAVFALEGALGGVM----DDKS-EDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCY 1175
G AA+F LEGALG D+KS E +T FG N P +SC FD YHLRCY
Sbjct: 1085 THGAAAIFKLEGALGADTTEDGDEKSLEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCY 1144
Query: 1176 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1235
+YQAR+L A+DKDSFSDPYA + FLH+S+ T ++ +TLNPTWDQT+IF E+EI+GEP TV
Sbjct: 1145 VYQARNLLALDKDSFSDPYAHICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQTV 1204
Query: 1236 AEQPPSIVVELYDHDTYGADEFMGRCICQP------SLERMPRLAWFPLTRGSQPSGELL 1289
+ PP +++EL+D+D G DEF+GR I P ++ P+L W P+ G + G++L
Sbjct: 1205 LQNPPKVIMELFDNDQVGKDEFLGRSIFSPVVKLNSEMDITPKLLWHPVMNGDKACGDVL 1264
Query: 1290 ASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQR 1349
+ ELI R K + ++LP PPQR N+YMVPQ I+P +Q
Sbjct: 1265 VTAELILRGK---------------------DGSNLPILPPQRAPNLYMVPQGIRPVVQL 1303
Query: 1350 TAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVML 1409
TAIEILAWGLRNMK++Q+A+I+SPSLVVECGG+ V+S VI+NL+K PNF LFM+V L
Sbjct: 1304 TAIEILAWGLRNMKNFQMASITSPSLVVECGGERVESVVIKNLKKTPNFPSSVLFMKVFL 1363
Query: 1410 PREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSA-ESPSPQGGPDDVSLL 1468
P+EELY PP+ +KVID+RQFGR+PVVGQCTI L+ F CDPY+ E PQ SLL
Sbjct: 1364 PKEELYMPPLVIKVIDHRQFGRKPVVGQCTIERLDRFRCDPYAGKEDIVPQ---LKASLL 1420
Query: 1469 S--PGEDVLIDIDDKEPLIPI----QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKV 1522
S P D++I+++D +PL+ +EEE +DWWSKF+AS GE EKCG Y++K + LK+
Sbjct: 1421 SAPPCRDIVIEMEDTKPLLASKLTEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKI 1480
Query: 1523 YDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPP 1582
Y+ +LENV FEGL+DF +TFKLYRGK+ +E EDPSV+GEFKG F+IYPLP+DP++P PP
Sbjct: 1481 YNCELENVAEFEGLTDFSDTFKLYRGKS-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPP 1539
Query: 1583 RQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1642
RQF +L PQEC VRIYIVR LQP+D NG CDPYIKI++GKK + D+D+YIP TL
Sbjct: 1540 RQFRELPDSVPQECTVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLN 1599
Query: 1643 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1702
PVFG+M+EL+C LP EKDLKI++YDYD ++DEK+GET++DLENR LS+FG+ CG+P+ Y
Sbjct: 1600 PVFGRMYELSCYLPQEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEY 1659
Query: 1703 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD--RVMFQDKEYSIEEIEAGRIPNPH 1760
CVSG N WRDQLRP+QLL + P+ D R+ + ++YS++E EA +I + H
Sbjct: 1660 CVSGVNTWRDQLRPTQLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQH 1719
Query: 1761 LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFN 1820
LG EERLALH+L+ QGLVPEHVE+R L+S QP+I QGKLQMWVD+FPK+LG PGPPFN
Sbjct: 1720 LGAPEERLALHILRTQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFN 1779
Query: 1821 ITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLG 1880
ITPR+A++++LR IIWNT+DVILD+ S+TGE+MSDIYVKGW+ G EE+KQKTDVHYRSL
Sbjct: 1780 ITPRKAKKYYLRVIIWNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLD 1839
Query: 1881 GEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFL 1940
GEGNFNWRF+FPFDYLPAEQ+C +AKK+ FW +D+TE +IP R++ QIWDNDKFS DD+L
Sbjct: 1840 GEGNFNWRFVFPFDYLPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYL 1899
Query: 1941 GSLQLDLNRMPKPAKTAKKCSLDQLDD--AFHP--EWFVSLFEQKTVKGWWPCVAEEGEK 1996
G L+LDL PAK+ +KC LD + D A +P SLFEQK++KGWWPC AE+
Sbjct: 1900 GFLELDLRHTIIPAKSPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGA 1959
Query: 1997 KILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFI 2056
+++AGK+EMTLEI+ E E +ERPAG+GRDEPNMNPKL+ P RP+TSFLWFT+P KTMKFI
Sbjct: 1960 RVMAGKVEMTLEILNEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFI 2019
Query: 2057 LWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2096
+WRRF+W II + L ILLLF+A+ +Y+ PNY +MK+VKP
Sbjct: 2020 VWRRFKWVIIGLLFLLILLLFVAVLLYSLPNYLSMKIVKP 2059
>gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens]
Length = 2093
Score = 1400 bits (3624), Expect = 0.0
Identities = 804/1970 (40%), Positives = 1126/1970 (57%), Gaps = 208/1970 (10%)
Query: 240 TSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLF 299
T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ +TRI GN+P FNE F
Sbjct: 155 TAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNPFFNEIFF 214
Query: 300 FNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPD 359
N + P + FDE I I + D+G IY P H LRKWL L P+
Sbjct: 215 QNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKWLGLCQPN 257
Query: 360 DFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFR 419
+ +G GYLK ++ LG GD+A +++K +D + + + V + A+ L ++
Sbjct: 258 NPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAYLQLFIYC 316
Query: 420 AEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT 479
AEDL K V+P +EV G+ L + + +T NP WNQ +T
Sbjct: 317 AEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILT 359
Query: 480 LPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDD----------- 528
P + ++ R++D + D + T LS+++IS+ G EIE
Sbjct: 360 FRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEPTSYTPRV 419
Query: 529 YLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQ 588
Y GFLP FGP ++ L+G + + + +G+AYRGR+ L L T++ + +
Sbjct: 420 YSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSYQDS 479
Query: 589 KVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLP 648
++DL + ++ R+EK+ R+KY L F S TM+ + + I FEVSIG+YGNK D+ P
Sbjct: 480 TIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNKMDLNYKP 538
Query: 649 LASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLE 708
L S+T YS ++DG Y+Y+PW N KPVV ++S WED+S R+ N L DRL+A L+
Sbjct: 539 LVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLD 598
Query: 709 QVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766
LK+ + +D L +L EL C +PL + P AT LD+ +QLR+ L
Sbjct: 599 ----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQLRSLLL 654
Query: 767 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826
+ LA K ++ + AEDWL RL + EPQ LPD++IW++ ++RVAY +
Sbjct: 655 QE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQ 709
Query: 827 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886
VPAH VLFS GA + G+ CGK+QT+FL+YP + +P +RV +W G D K+
Sbjct: 710 VPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTDSKDLQ 769
Query: 887 QFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDSFRPSAGWTWA 945
+G +V+AE YEN+ K WG GL + P FSDV G LP F+P GW W
Sbjct: 770 LLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGWHWQ 827
Query: 946 GDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIE 1005
W V P++ LL D+D +EEV+ENQ R G W + TDVNG+ + +++++
Sbjct: 828 DSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARENVK 887
Query: 1006 CPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRR 1065
CP GW ++ ++W +LN AVD WEY + IPP P+ W P EK Y++ RRRRW R+R
Sbjct: 888 CPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWARVRF 944
Query: 1066 RDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRR 1115
R+ ++ H Q A+ E EGWEY + FG KFHL + FRRR WRRR
Sbjct: 945 RNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQSRFRRRCWRRR 999
Query: 1116 MEPLEKTGPAAVFALEGAL----GGVMDD------------------------------- 1140
+ P + G A +F LEG+L G V ++
Sbjct: 1000 LAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDLKYH 1059
Query: 1141 --KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLRCYMYQARDLA 1183
K EDS T +G++R P I C F+ + Y L CY+YQAR+L
Sbjct: 1060 AGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQARNLV 1116
Query: 1184 AMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIV 1243
+ +F P+ V FL+ SQ T ++++ PTW QTLIF + ++ P E PP +V
Sbjct: 1117 SNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTKESPPLVV 1176
Query: 1244 VELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSGELLASFELI- 1295
+EL+ D +G + GR + P + +P + W PL + + GE+LAS ELI
Sbjct: 1177 LELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEILASCELIL 1236
Query: 1296 QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEIL 1355
Q EK +P V P+ + Y +P++I+P ++R AIEIL
Sbjct: 1237 QTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQPTIKRMAIEIL 1276
Query: 1356 AWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREE 1413
AWGLRNMK SSP L+VE G +++++ IR+ + NPNF L + V++P EE
Sbjct: 1277 AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEE 1331
Query: 1414 LYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG-- 1471
Y P+ VKV+DN FG++ V GQ I L+ + CDP++ + P+ + LS
Sbjct: 1332 AYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKH 1386
Query: 1472 EDVLIDIDDK----EPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQL 1527
+D L + K + E +DWWSK F + E + Y KD+ TLKVY+ +L
Sbjct: 1387 QDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECEL 1445
Query: 1528 ENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQ 1587
E V AF+GL DFC TFKLY+ ++ D V+GEFKGLF+IYP PE+P P PP QF
Sbjct: 1446 EAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLV 1502
Query: 1588 LAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1645
+ PQ CLVR+Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+P+F
Sbjct: 1503 WPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIF 1562
Query: 1646 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1705
G MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC S
Sbjct: 1563 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQS 1622
Query: 1706 GPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LG 1762
GP +WRDQ+ PS LL + ++ + P++ D V + K++ ++ E + P H LG
Sbjct: 1623 GPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLG 1681
Query: 1763 PVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNIT 1822
P +ERLAL++L QGLVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP NI
Sbjct: 1682 PKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNIN 1741
Query: 1823 PRRAR---------RFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTD 1873
PR+ + R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+ QKTD
Sbjct: 1742 PRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTD 1801
Query: 1874 VHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDK 1933
+HY SL GE +FNWRFIF DYL AE+ C ++KD W LD T K PAR++ Q+WDND
Sbjct: 1802 IHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDI 1861
Query: 1934 FSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGW 1986
FS DDFLG L+LDL+ MP PA+ AK+CS+ +D P+W SLF++KTV GW
Sbjct: 1862 FSPDDFLGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGW 1919
Query: 1987 WPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWF 2046
WPC +G K L+GK++M+LEI++E E +PAG+G+ EPN P L P R +TSF W
Sbjct: 1920 WPCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWL 1979
Query: 2047 TSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2096
SP + +I W+R+R+ +I F+++ I+ L L FIY+ P+Y AM +KP
Sbjct: 1980 RSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 2029
Score = 65.9 bits (159), Expect = 4e-10
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 2/103 (1%)
Query: 23 PVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNRFL 82
P S+ FR +KKRT+V++ + +PVWNE W L PL+ S L V ++D + + RF+
Sbjct: 21 PCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLENDSFLQVTLQDMGSQKKERFI 79
Query: 83 GEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVLQVSY 124
G A V L+ +L PS + + LL+ +PT ++ LQV++
Sbjct: 80 GLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQVAH 122
Score = 40.0 bits (92), Expect = 0.024
Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query: 270 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 329
+P + + KRTR+ +GN P++NETL ++L++ P E D + +T+ D S + +
Sbjct: 20 RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78
Query: 330 LGEFRMDVGTIYREPRHAYLRKWLLL 355
+G + + + ++P K L L
Sbjct: 79 IGLATVLLKPLLKQPSEVLFVKDLTL 104
>gi|35493868 otoferlin isoform b [Homo sapiens]
Length = 1230
Score = 720 bits (1858), Expect = 0.0
Identities = 408/1057 (38%), Positives = 584/1057 (55%), Gaps = 149/1057 (14%)
Query: 1158 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1217
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 201 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260
Query: 1218 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1270
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 261 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320
Query: 1271 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1327
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 321 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360
Query: 1328 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1384
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 361 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420
Query: 1385 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1444
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 421 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480
Query: 1445 SFLCDPYSAESPSPQGGPDDVSLLSPG---------------EDVLIDID---------- 1479
F+ P +PS + V + P + ++ +D
Sbjct: 481 RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540
Query: 1480 -----DKEPLIPIQEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1516
+EP +E +DWWSK+FASI ++E G LE+
Sbjct: 541 KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600
Query: 1517 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1539
D LKVY +LE+ F+ D+
Sbjct: 601 SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658
Query: 1540 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1589
+TF L RGKT ++ TE+ ++G FKG +Y PLPED + F +
Sbjct: 659 LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718
Query: 1590 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1649
+ P LVR+Y+VRA L P D NGK DPYI I +GK + D++NYI L PVFGK F
Sbjct: 719 SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778
Query: 1650 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1709
++ + P+E L + +YD+DL+ D+ IGET +DLENR SK A CG+ QTY G N
Sbjct: 779 DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838
Query: 1710 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1767
WRD ++PSQ+L C+ +V P + RV ++ ++ EIE N P +E
Sbjct: 839 WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895
Query: 1768 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1819
+AL L+ LVPEHVE+RPL +P +P IEQG+L++WVD+FP + PG P
Sbjct: 896 VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955
Query: 1820 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1878
+I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V+GW+ G +E KQ TDVHY S
Sbjct: 956 DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015
Query: 1879 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1938
L GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE KIPAR+ QIWD D FS DD
Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075
Query: 1939 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 1997
FLG+++LDLNR P+ AKTAK+C+++ VS+F+QK VKGWWP +A E ++
Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134
Query: 1998 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2057
L GK+E L ++ E E+ P G R+EP+ LE P RPDTSF+WF +P K+ ++ L
Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTSFIWFLNPLKSARYFL 1191
Query: 2058 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2094
W +RW ++ ++L +LLL LA+F+Y+ P Y K++
Sbjct: 1192 WHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1228
Score = 87.4 bits (215), Expect = 1e-16
Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%)
Query: 732 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 786
+EL GC + L D + S+ T LD+ + L + + A L+ + +
Sbjct: 18 EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77
Query: 787 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 846
L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C
Sbjct: 78 LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136
Query: 847 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 885
K++T+FLK P ++ G A VQ +V+ LW GLS KEF
Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 440 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 476
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262
>gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens]
Length = 802
Score = 714 bits (1842), Expect = 0.0
Identities = 366/746 (49%), Positives = 494/746 (66%), Gaps = 32/746 (4%)
Query: 1371 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1428
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
Query: 1429 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----E 1482
FG++ V GQ I L+ + CDP++ + P+ + LS +D L + K
Sbjct: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKS 119
Query: 1483 PLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNT 1542
+ E +DWWSK F + E + Y KD+ TLKVY+ +LE V AF+GL DFC T
Sbjct: 120 SKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQT 178
Query: 1543 FKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRI 1600
FKLY+ ++ D V+GEFKGLF+IYP PE+P P PP QF + PQ CLVR+
Sbjct: 179 FKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRV 235
Query: 1601 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1660
Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+P+FG MFELTC +PLEKD
Sbjct: 236 YMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKD 295
Query: 1661 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1720
L+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL
Sbjct: 296 LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLL 355
Query: 1721 HLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQG 1777
+ ++ + P++ D V + K++ ++ E + P H LGP +ERLAL++L QG
Sbjct: 356 ERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQG 414
Query: 1778 LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWN 1837
LVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP NI PR+ +R+ LRCIIW
Sbjct: 415 LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474
Query: 1838 TRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLP 1897
T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL
Sbjct: 475 TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534
Query: 1898 AEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTA 1957
AE+ C ++KD W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ A
Sbjct: 535 AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594
Query: 1958 KKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 2010
K+CS+ +D P+W SLF++KTV GWWPC +G K L+GK++M+LEI+
Sbjct: 595 KQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEIL 652
Query: 2011 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2070
+E E +PAG+G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F++
Sbjct: 653 SEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMV 712
Query: 2071 LFILLLFLAIFIYAFPNYAAMKLVKP 2096
+ I+ L L FIY+ P+Y AM +KP
Sbjct: 713 ISIIALMLFNFIYSAPHYLAMSWIKP 738
>gi|35493853 otoferlin isoform c [Homo sapiens]
Length = 1307
Score = 712 bits (1839), Expect = 0.0
Identities = 410/1077 (38%), Positives = 584/1077 (54%), Gaps = 169/1077 (15%)
Query: 1158 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1217
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 258 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 317
Query: 1218 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1270
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 318 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 377
Query: 1271 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1327
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 378 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 417
Query: 1328 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1384
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 418 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 477
Query: 1385 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1444
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 478 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 537
Query: 1445 SFLCDPYSAESPS--------------PQGGPDDVSL---------------------LS 1469
F+ P +PS GG S L
Sbjct: 538 RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGSSSHSTGEVVVTMEPEVPIKKLETMVKLD 597
Query: 1470 PGEDVLIDID---------------DKEPLIPIQEEEFIDWWSKFFASIG-------ERE 1507
+ ++ +D +EP +E +DWWSK+FASI ++E
Sbjct: 598 ATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQE 657
Query: 1508 KCGSYLEKD------------------------------------------------FDT 1519
G LE+ D
Sbjct: 658 PSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDE 717
Query: 1520 LKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLP 1573
LKVY +LE+ F+ D+ +TF L RGKT ++ TE+ ++G FKG +Y PLP
Sbjct: 718 LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 775
Query: 1574 EDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKS 1629
ED + F + + P LVR+Y+VRA L P D NGK DPYI I +GK
Sbjct: 776 EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 835
Query: 1630 VSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLL 1689
+ D++NYI L PVFGK F++ + P+E L + +YD+DL+ D+ IGET +DLENR
Sbjct: 836 IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 895
Query: 1690 SKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS- 1747
SK A CG+ QTY G N WRD ++PSQ+L C+ +V P + RV ++ ++
Sbjct: 896 SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 955
Query: 1748 IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQG 1799
EIE N P +E +AL L+ LVPEHVE+RPL +P +P IEQG
Sbjct: 956 PSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQG 1012
Query: 1800 KLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYV 1858
+L++WVD+FP + PG P +I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V
Sbjct: 1013 RLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFV 1072
Query: 1859 KGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTES 1918
+GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE
Sbjct: 1073 RGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEY 1132
Query: 1919 KIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLF 1978
KIPAR+ QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++ VS+F
Sbjct: 1133 KIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIF 1191
Query: 1979 EQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2037
+QK VKGWWP +A E ++ L GK+E L ++ E E+ P G R+EP+ LE P
Sbjct: 1192 KQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPN 1248
Query: 2038 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2094
RPDTSF+WF +P K+ ++ LW +RW ++ ++L +LLL LA+F+Y+ P Y K++
Sbjct: 1249 RPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1305
Score = 91.3 bits (225), Expect = 9e-18
Identities = 71/211 (33%), Positives = 110/211 (52%), Gaps = 21/211 (9%)
Query: 683 WEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQ-- 740
W I+H ++Q E GL + +K + S + + + +EL GC +
Sbjct: 38 WPSITHTPDSQ----------EEGLNDIQEMIKTEKSYPE--RRLRGVLEELSCGCCRFL 85
Query: 741 PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAALEQAEDWLLRL 797
L D + S+ T LD+ + L + + A L+ + + L +++L +L
Sbjct: 86 SLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKL 145
Query: 798 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 857
R LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C K++T+FLK P
Sbjct: 146 RFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDCAKVKTLFLKLP 204
Query: 858 MEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 885
++ G A VQ +V+ LW GLS KEF
Sbjct: 205 GKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 235
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 440 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 476
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 283 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 319
>gi|35493860 otoferlin isoform d [Homo sapiens]
Length = 1230
Score = 712 bits (1839), Expect = 0.0
Identities = 406/1057 (38%), Positives = 583/1057 (55%), Gaps = 149/1057 (14%)
Query: 1158 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1217
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 201 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260
Query: 1218 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1270
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 261 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320
Query: 1271 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1327
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 321 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360
Query: 1328 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1384
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 361 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420
Query: 1385 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1444
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 421 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480
Query: 1445 SFLCDPYSAESPSPQGGPDDVSLLSPG---------------EDVLIDID---------- 1479
F+ P +PS + V + P + ++ +D
Sbjct: 481 RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540
Query: 1480 -----DKEPLIPIQEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1516
+EP +E +DWWSK+FASI ++E G LE+
Sbjct: 541 KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600
Query: 1517 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1539
D LKVY +LE+ F+ D+
Sbjct: 601 SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658
Query: 1540 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1589
+TF L RGKT ++ TE+ ++G FKG +Y PLPED + F +
Sbjct: 659 LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718
Query: 1590 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1649
+ P LVR+Y+VRA L P D NGK DPYI I +GK + D++NYI L PVFGK F
Sbjct: 719 SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778
Query: 1650 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1709
++ + P+E L + +YD+DL+ D+ IGET +DLENR SK A CG+ QTY G N
Sbjct: 779 DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838
Query: 1710 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1767
WRD ++PSQ+L C+ +V P + RV ++ ++ EIE N P +E
Sbjct: 839 WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895
Query: 1768 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1819
+AL L+ LVPEHVE+RPL +P +P IEQG+L++WVD+FP + PG P
Sbjct: 896 VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955
Query: 1820 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1878
+I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V+GW+ G +E KQ TDVHY S
Sbjct: 956 DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015
Query: 1879 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1938
L GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE KIPAR+ QIWD D FS DD
Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075
Query: 1939 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 1997
FLG+++LDLNR P+ AKTAK+C+++ VS+F+QK VKGWWP +A E ++
Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134
Query: 1998 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2057
L GK+E L ++ E E+ P G R+EP+ LE P RPDT+F+WF +P K++K+++
Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTAFVWFLNPLKSIKYLI 1191
Query: 2058 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2094
R++W II ++ + LL L +F+Y+ P Y KL+
Sbjct: 1192 CTRYKWLIIKIVLALLGLLMLGLFLYSLPGYMVKKLL 1228
Score = 87.4 bits (215), Expect = 1e-16
Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%)
Query: 732 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 786
+EL GC + L D + S+ T LD+ + L + + A L+ + +
Sbjct: 18 EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77
Query: 787 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 846
L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C
Sbjct: 78 LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136
Query: 847 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 885
K++T+FLK P ++ G A VQ +V+ LW GLS KEF
Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 440 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 476
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262
>gi|34740331 otoferlin isoform a [Homo sapiens]
Length = 1997
Score = 712 bits (1839), Expect = 0.0
Identities = 410/1077 (38%), Positives = 584/1077 (54%), Gaps = 169/1077 (15%)
Query: 1158 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1217
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 948 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 1007
Query: 1218 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1270
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 1008 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 1067
Query: 1271 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1327
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 1068 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 1107
Query: 1328 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1384
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 1108 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 1167
Query: 1385 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1444
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 1168 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 1227
Query: 1445 SFLCDPYSAESPS--------------PQGGPDDVSL---------------------LS 1469
F+ P +PS GG S L
Sbjct: 1228 RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGSSSHSTGEVVVTMEPEVPIKKLETMVKLD 1287
Query: 1470 PGEDVLIDID---------------DKEPLIPIQEEEFIDWWSKFFASIG-------ERE 1507
+ ++ +D +EP +E +DWWSK+FASI ++E
Sbjct: 1288 ATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQE 1347
Query: 1508 KCGSYLEKD------------------------------------------------FDT 1519
G LE+ D
Sbjct: 1348 PSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDE 1407
Query: 1520 LKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLP 1573
LKVY +LE+ F+ D+ +TF L RGKT ++ TE+ ++G FKG +Y PLP
Sbjct: 1408 LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 1465
Query: 1574 EDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKS 1629
ED + F + + P LVR+Y+VRA L P D NGK DPYI I +GK
Sbjct: 1466 EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 1525
Query: 1630 VSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLL 1689
+ D++NYI L PVFGK F++ + P+E L + +YD+DL+ D+ IGET +DLENR
Sbjct: 1526 IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 1585
Query: 1690 SKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS- 1747
SK A CG+ QTY G N WRD ++PSQ+L C+ +V P + RV ++ ++
Sbjct: 1586 SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 1645
Query: 1748 IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQG 1799
EIE N P +E +AL L+ LVPEHVE+RPL +P +P IEQG
Sbjct: 1646 PSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQG 1702
Query: 1800 KLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYV 1858
+L++WVD+FP + PG P +I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V
Sbjct: 1703 RLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFV 1762
Query: 1859 KGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTES 1918
+GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE
Sbjct: 1763 RGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEY 1822
Query: 1919 KIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLF 1978
KIPAR+ QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++ VS+F
Sbjct: 1823 KIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIF 1881
Query: 1979 EQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2037
+QK VKGWWP +A E ++ L GK+E L ++ E E+ P G R+EP+ LE P
Sbjct: 1882 KQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPN 1938
Query: 2038 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2094
RPDTSF+WF +P K+ ++ LW +RW ++ ++L +LLL LA+F+Y+ P Y K++
Sbjct: 1939 RPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1995
Score = 401 bits (1031), Expect = e-111
Identities = 299/944 (31%), Positives = 475/944 (50%), Gaps = 112/944 (11%)
Query: 20 RSDPVASLTFRGVKKRTKVIKNSVNPV-WNEGFEWDLKGIPLDQGSELHVVVKDHETMGR 78
R D +A +TFRG ++V++N + ++E F W + +D+ L + V ++ +
Sbjct: 16 RGDRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVAS-SIDRNEMLEIQVFNYSKVFS 74
Query: 79 NRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPPPT 138
N+ +G ++ L++V+ + + L+D SL ++V Y G V +
Sbjct: 75 NKLIGTFRMVLQKVVEESHVEVTDT--LIDDNNAIIKTSLCVEVRYQATDGTVGSWDDGD 132
Query: 139 PL------EPSPTLPDLDVVAGGGQS----------RAETWSLLSDSTMDTRYSGKKWPA 182
L E + D + G + R S+ S + S K+ P
Sbjct: 133 FLGDESLQEEEKDSQETDGLLPGSRPSSRPPGEKSFRRAGRSVFSAMKLGKNRSHKEEPQ 192
Query: 183 PTDTGGEEDTEDQG----LTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSA 238
D + ED GD +P A TT + KRS
Sbjct: 193 RPDEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTT-------------NVSNKRSK 239
Query: 239 PTSRKLLS-DKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNE 296
P + S +P D+Q+ + VIE RQL G+N+ PVV V K T + + N P +NE
Sbjct: 240 PDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNE 299
Query: 297 TLFFNLFDSPGELFDEPIFITVVDSRSL-RTDALLGEFRMDVGTIYREPRHAYLRKWLLL 355
F+ SP +FD+ I I+V+ S++L R+ L+G F+MDVGT+Y +P H + KW +L
Sbjct: 300 YFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAIL 359
Query: 356 SDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGV--ALRGAHF 413
SDPDD S+G +GY+K + V+G GD K D++DIE NLL P GV + A F
Sbjct: 360 SDPDDISSGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARF 419
Query: 414 CLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQ 473
+K++RAE LP+M+ ++M NVK+ F E+ K+LVDP+V+V FAG+ + + + + P
Sbjct: 420 YVKIYRAEGLPRMNTSLMANVKKAFIGEN--KDLVDPYVQVFFAGQKGKTSVQKSSYEPL 477
Query: 474 WNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEVDDYLGF 532
WN+ + +FP +C++M+++I D D++ ND+ + T ++ + KIS G + GF
Sbjct: 478 WNEQVVFTDLFPPLCKRMKVQIRDSDKV--NDVAIGTHFIDLRKISNDGDK-------GF 528
Query: 533 LPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVED 592
LPT GP ++N+YGS R +T D + +LN G GEGV++R RLLL L ++V+ S +
Sbjct: 529 LPTLGPAWVNMYGSTRNYT-LLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSN---PE 584
Query: 593 LPADDILRVEKYL--------RRRKYSLFAAFYSATML--QDVDDAIQFEVSIGNYGNKF 642
L + ++VE+ + ++ LF AF A+M+ ++ D I FEV+IGNYGN+
Sbjct: 585 LTSSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDRRNGDKPITFEVTIGNYGNEV 644
Query: 643 DMTCLP---------------------------------LASTTQYSRAVFDGCHYYYLP 669
D P S+T R +Y++LP
Sbjct: 645 DGLSRPQRPRPRKEPGDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVTDRNYFHLP 704
Query: 670 WGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQ 729
+ KP + + S+W D R+ N + IAD+LE GL + +K + S + +
Sbjct: 705 YLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYP--ERRLRG 762
Query: 730 LTDELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAA--LALKLGHSELP 784
+ +EL GC + L D + S+ T LD+ + L + + A L ++ +
Sbjct: 763 VLEELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVR 822
Query: 785 AALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGK 844
L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK
Sbjct: 823 DKLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGK 881
Query: 845 NCGKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 885
+C K++T+FLK P ++ G A VQ +V+ LW GLS KEF
Sbjct: 882 DCAKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 925
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 440 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 476
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 973 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 1009
Score = 32.3 bits (72), Expect = 5.0
Identities = 13/35 (37%), Positives = 21/35 (60%)
Query: 1192 DPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1226
DPY V F Q KT V K++ P W++ ++F ++
Sbjct: 453 DPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDL 487
>gi|119120884 fer-1-like 6 [Homo sapiens]
Length = 1857
Score = 709 bits (1830), Expect = 0.0
Identities = 405/1085 (37%), Positives = 580/1085 (53%), Gaps = 172/1085 (15%)
Query: 1148 VSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTV 1207
+S+ G N P + ++ + + LR +MYQAR L A D + SDP+A V+FL Q T
Sbjct: 804 MSSKGAGTNHPPSNLLYQEQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSHCQTTK 863
Query: 1208 VVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL 1267
++ TL+PTW+Q L+F ++ + G+ +AE PP +VVELYD D G E++G + P +
Sbjct: 864 IISQTLSPTWNQMLLFNDLVLHGDVKELAESPPLVVVELYDSDAVGKPEYLGATVAAPVV 923
Query: 1268 E------RMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1321
+ PRL + P+ G+ G+LLA FEL+Q + +P
Sbjct: 924 KLADQDYEPPRLCYHPIFCGNLSGGDLLAVFELLQVPPSGLQGLP--------------- 968
Query: 1322 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1381
P PP IY VP NI+P L + +E+L WG+R MK QL ++ P ++ECGG
Sbjct: 969 ----PVEPPDI-TQIYPVPANIRPVLSKYRVEVLFWGVREMKKVQLLSVDRPQALIECGG 1023
Query: 1382 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1441
Q V+SCVI++ + NPNF I EV LP EL PP+++ V+D R FGR +VG TI
Sbjct: 1024 QGVKSCVIQSYKNNPNFSIQADAFEVELPENELLHPPLSICVVDWRAFGRSTLVGTYTIN 1083
Query: 1442 SLESFLC--------------------------------------DP-----YSAESPSP 1458
L+ FLC DP Y P P
Sbjct: 1084 YLKQFLCKLREPLAPITQVDGTQPGHDISDSLTATESSGAHSSSQDPPADHIYVDVEPPP 1143
Query: 1459 QGGPDDVSLLSPGEDVLIDIDDKEPLI-----PIQEE----------------------- 1490
PD +L+D+ D P++ P+ +E
Sbjct: 1144 TVVPDSAQAQPA---ILVDVPDSSPMLEPEHTPVAQEPPKDGKPKDPRKPSRRSTKRRKR 1200
Query: 1491 --------EFIDWWSKFFASI-------------------------------GEREKCGS 1511
IDWWSK++AS+ G ++K
Sbjct: 1201 TIADESAENVIDWWSKYYASLKKAQKAKERNPKGKKGNTEAKPDEVVVDIEDGPKKKKDK 1260
Query: 1512 YLEK--------DFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEET---EDPSVI 1560
L+K + L++YD LE+ F D+ TF+L+RGK+ E+ + VI
Sbjct: 1261 MLKKKPKDDGIPNLAILQIYDGDLES--EFNNFEDWVKTFELFRGKSTEDDHGLDGDRVI 1318
Query: 1561 GEFKGLFKIYPLPEDPAIPMPPRQFHQ--LAAQGPQECLVRIYIVRAFGLQPKDPNGKCD 1618
G+FKG F IY P+D + + Q + P L+R+YIV AF L P DP+GK D
Sbjct: 1319 GKFKGSFCIYKSPQDSSSEDSGQLRIQQGIPPNHPVTVLIRVYIVAAFNLSPADPDGKSD 1378
Query: 1619 PYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIG 1678
PYI I +GK + D+D YIP L PVFG+ FE+ T P E L I +YD+D++ D+ IG
Sbjct: 1379 PYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSILIYDHDMIGTDDLIG 1438
Query: 1679 ETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDR 1738
ET +DLENR SK A CGL Y + G N WRD +P+++L C+ +++ P + +
Sbjct: 1439 ETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYFHPGK 1498
Query: 1739 VMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYS 1790
+ ++ +S + I + + E LAL VL LVPEH+E+RPLY
Sbjct: 1499 IQIGNQVFSGKTIFTEEDTDETVESYEH-LALKVLHSWEDIPEVGCRLVPEHIETRPLYH 1557
Query: 1791 PLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSL-T 1849
+P +EQG+LQMWVD+FPK + +PGPP +I+PRR + + LR IWNT DVIL+D ++ T
Sbjct: 1558 KDKPGMEQGRLQMWVDMFPKDMPQPGPPVDISPRRPKGYELRVTIWNTEDVILEDENIFT 1617
Query: 1850 GEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDA 1909
G+K SDIYVKGW+ G E+ KQ+TDVHY SL GEGNFNWRF+FPF YLPAE+ I K++
Sbjct: 1618 GQKSSDIYVKGWLKGLEDDKQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVITKREN 1677
Query: 1910 FWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAF 1969
+ L+K E K PA +V Q+WD ++ S DDFLG+L+++LN P+ AK+AK C L + ++A
Sbjct: 1678 IFSLEKMECKTPAVLVLQVWDFERLSSDDFLGTLEMNLNSFPRAAKSAKACDLAKFENA- 1736
Query: 1970 HPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNM 2029
E +S+F+QK V+GWWP + K L GK+E +V E E+ P G+ R EP
Sbjct: 1737 SEETKISIFQQKRVRGWWPF----SKSKELTGKVEAEFHLVTAEEAEKNPVGKARKEPE- 1791
Query: 2030 NPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYA 2089
L P RPDTSF WF SP+K + +++W+ ++ II+ IL IL++FL +FIY P
Sbjct: 1792 --PLAKPNRPDTSFSWFMSPFKCLYYLIWKNYKKYIIIAFILIILIIFLVLFIYTLPGAI 1849
Query: 2090 AMKLV 2094
+ ++V
Sbjct: 1850 SRRIV 1854
Score = 348 bits (893), Expect = 3e-95
Identities = 236/724 (32%), Positives = 372/724 (51%), Gaps = 112/724 (15%)
Query: 248 KPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNETLFFNLFDSP 306
+ Q++QI + + E RQL G NI PVV + + K++ + +G NSP +NE F+
Sbjct: 79 RSQNYQIAITITEARQLVGENIDPVVTIEIGDEKKQSTVKEGTNSPFYNEYFVFDFIGPQ 138
Query: 307 GELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGAR 366
LFD+ I I+V + + + L+G F++D+GT+Y +P H + KW LL+DP D G +
Sbjct: 139 VHLFDKIIKISVFHHKLIGS-VLIGSFKVDLGTVYNQPGHQFCNKWALLTDPGDIRTGTK 197
Query: 367 GYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALR--GAHFCLKVFRAEDLP 424
GYLK + V+G GD K S+ +E IE NLL P G L A F +++++AE LP
Sbjct: 198 GYLKCDISVMGKGDVLKTSPK-TSDTEEPIEKNLLIPNGFPLERPWARFYVRLYKAEGLP 256
Query: 425 QMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMF 484
+M+ ++M NV + F + K+LVDPFVEVSFAG+M + + + A+P W++ + MF
Sbjct: 257 KMNSSIMANVTK--AFVGDSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEMF 314
Query: 485 PSMCEKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYINL 543
P +C +++I++ WD + ND+ +AT ++ + KIS E D GFLPTFGP +INL
Sbjct: 315 PPLCRRVKIQV--WDEGSMNDVALATHFIDLKKISN-----EQDGDKGFLPTFGPAWINL 367
Query: 544 YGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQ--------KVEDLPA 595
YGSPR + D Y E+N G GEGV++RGR+L+ + +++ Q K LP+
Sbjct: 368 YGSPRNHS-LMDDYQEMNEGFGEGVSFRGRILVEIAVEILSGRAQESKFSKALKELKLPS 426
Query: 596 DD------------------------------ILRVEKY--------LRRRKYSLFAAFY 617
D + VE + + ++ LF AF+
Sbjct: 427 KDKDSKSSKGKDKADKTEDGKSQQASNKTNSTEVEVESFDVPPEIVPEKNEEFLLFGAFF 486
Query: 618 SATMLQDV--DDAIQFEVSIGNYGNKFD-------------------------------M 644
ATM+ D I FEVSIGN+GN D
Sbjct: 487 EATMIDRKIGDKPISFEVSIGNFGNLIDGGSHHGSKKSAESAEEDLLPLLHEGQGDVAHD 546
Query: 645 TCLPLASTTQYSRAVF--DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADR 702
+P+ASTT + + +Y YLP+ KP V S W D + R+ N L +AD
Sbjct: 547 VPIPMASTTHPEKPLVTEGNRNYNYLPFEAKKPCVYFISSWGDQTFRLHWSNMLEKMADF 606
Query: 703 LEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETP---SATHLDQYLY 759
LE +E+V +K S E + + + + I+ S + + + P + T LD+
Sbjct: 607 LEESIEEVRELIK--ISQEAPEEKMKTVLSDFISRSSAFISEAEKKPKMLNQTTLDKKRL 664
Query: 760 QLRTHHLSQITEAALAL------KLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVI 813
L L + + A + KL E+ + +A++++ ++R L +EPQ+++PD+ I
Sbjct: 665 TLCWQELEAMCKEAKGIIQQQKKKLSVDEM---IHEAQNFVEKIRFLVDEPQHTIPDVFI 721
Query: 814 WMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVK 873
WML ++RVAY R+ + +L+S A GK+CGK++T FLK P ++ G + ++ V
Sbjct: 722 WMLSNNRRVAYARIASKDLLYS-PVAGQMGKHCGKIKTHFLKPPGKRPAGWSVQAKVDVY 780
Query: 874 LWFG 877
LW G
Sbjct: 781 LWLG 784
Score = 45.4 bits (106), Expect = 6e-04
Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
Query: 6 LVRASNLPSAKKDRRSDP--VASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQG 63
+V A NL A D +SDP V L +K R K I +NPV+ FE +
Sbjct: 1362 IVAAFNLSPADPDGKSDPYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQAT---FPKE 1418
Query: 64 SELHVVVKDHETMGRNRFLGEAKVPL 89
S L +++ DH+ +G + +GE K+ L
Sbjct: 1419 SLLSILIYDHDMIGTDDLIGETKIDL 1444
Score = 35.8 bits (81), Expect = 0.45
Identities = 16/41 (39%), Positives = 22/41 (53%)
Query: 1186 DKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1226
D DP+ VSF Q +T V KN +P W + +IF E+
Sbjct: 273 DSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEM 313
Score = 34.3 bits (77), Expect = 1.3
Identities = 15/44 (34%), Positives = 26/44 (59%)
Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNE 49
+ +A L +A + SDP A +TF + TK+I +++P WN+
Sbjct: 832 MYQARGLIAADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQ 875
Score = 34.3 bits (77), Expect = 1.3
Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 8/93 (8%)
Query: 442 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ-----NITLPAMFPSMCEKMRIRII 496
++ L DPF +V+F +KI+ +T +P WNQ ++ L + E + ++
Sbjct: 841 ADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQMLLFNDLVLHGDVKELAESPPLVVV 900
Query: 497 DWDRLTHNDIVATTYLSMSKISAPGGEIEVDDY 529
+ L +D V + ++AP ++ DY
Sbjct: 901 E---LYDSDAVGKPEYLGATVAAPVVKLADQDY 930
>gi|4759026 RAS protein activator like 1 [Homo sapiens]
Length = 804
Score = 65.5 bits (158), Expect = 5e-10
Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 13/127 (10%)
Query: 1172 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1231
LRC++ ARDLA D SDP+A V + QS +T +K T P WD+ L E
Sbjct: 135 LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVL---------E 185
Query: 1232 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQP-SLERMPRLAWF---PLTRGSQPSGE 1287
+ P + VEL+D D G ++F+G P +L++ P WF P R + SG
Sbjct: 186 LREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAEEDSGG 245
Query: 1288 LLASFEL 1294
L + +
Sbjct: 246 NLGALRV 252
Score = 43.9 bits (102), Expect = 0.002
Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 13/167 (7%)
Query: 1512 YLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYP 1571
+L DF L Y + V G D L R + T DP I + L ++ P
Sbjct: 60 HLPLDFHQLAFYVLDEDTV----GHDDIIGKISLSR---EAITADPRGIDSWINLSRVDP 112
Query: 1572 LPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVS 1631
D + Q+ G CL R +++ A L P+D +G DP+ ++ G +S+
Sbjct: 113 ---DAEVQGEICLSVQMLEDGQGRCL-RCHVLHARDLAPRDISGTSDPFARVFWGSQSL- 167
Query: 1632 DQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIG 1678
+ + I T P + ++ EL L++ L+D+D++ K++ +G
Sbjct: 168 -ETSTIKKTRFPHWDEVLELREMPGAPSPLRVELWDWDMVGKNDFLG 213
Score = 43.5 bits (101), Expect = 0.002
Identities = 59/268 (22%), Positives = 100/268 (37%), Gaps = 64/268 (23%)
Query: 254 IRVQVIEGRQLPGVNIKP------VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPG 307
+ V+V+EGR LP ++ +VKV + + + P + E +L
Sbjct: 7 LNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVHL----- 61
Query: 308 ELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLS--DPDDFSAGA 365
L + V+D ++ D ++G+ + I +PR + W+ LS DPD A
Sbjct: 62 PLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRG--IDSWINLSRVDPD---AEV 116
Query: 366 RGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQ 425
+G + S+ +L ED + LR V A DL
Sbjct: 117 QGEICLSVQML-----------------EDGQGRCLR------------CHVLHARDLAP 147
Query: 426 MDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFP 485
D + DPF V + + L + ++KT P W++ + L M P
Sbjct: 148 RDIS----------------GTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREM-P 190
Query: 486 SMCEKMRIRIIDWDRLTHNDIVATTYLS 513
+R+ + DWD + ND + S
Sbjct: 191 GAPSPLRVELWDWDMVGKNDFLGMVEFS 218
Score = 35.0 bits (79), Expect = 0.77
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 5/83 (6%)
Query: 2 LCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEW-DLKGIPL 60
L C ++ A +L SDP A + + T IK + P W+E E ++ G P
Sbjct: 135 LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGAP- 193
Query: 61 DQGSELHVVVKDHETMGRNRFLG 83
S L V + D + +G+N FLG
Sbjct: 194 ---SPLRVELWDWDMVGKNDFLG 213
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 54.3 bits (129), Expect = 1e-06
Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%)
Query: 1145 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1189
S SVS G ++PT + +D GN L ++ QAR+L D +
Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726
Query: 1190 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1235
+SDP+ V L + +VV+N +LNP W+QT+I+ I +
Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780
Query: 1236 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1289
+ ++ V ++D+D + +++F+G + S L+ PR W+PL ++ G+
Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838
Query: 1290 ASFELIQREKPAI 1302
+S Q KP++
Sbjct: 4839 SSQSSQQSPKPSV 4851
Score = 43.5 bits (101), Expect = 0.002
Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%)
Query: 1600 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1647
I+I++A L P+D NG DP++K+ + G+ V N ++ +L P + +
Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770
Query: 1648 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1686
++ +K L++T++DYD S ++ +GE ++DL +
Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812
Score = 41.2 bits (95), Expect = 0.011
Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 21/142 (14%)
Query: 33 KKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKVPLR 90
K+RTK ++ S+NP WN+ + K I ++Q L V V D++ N FLGE + L
Sbjct: 4754 KRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDL- 4810
Query: 91 EVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPPPTP 139
S S N P K+ T G S Q S +P P + +FP P+
Sbjct: 4811 -----SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSK 4865
Query: 140 LEPSPTLPDLDVVAGGGQSRAE 161
PT+ G +S +E
Sbjct: 4866 DMQVPTIEKSHSSPGSSKSSSE 4887
Score = 36.6 bits (83), Expect = 0.27
Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Query: 463 SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 518
+K ++K+ NP+WNQ + ++ +K + + + D+DR + ND + + +S S
Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814
Score = 34.7 bits (78), Expect = 1.0
Identities = 53/211 (25%), Positives = 74/211 (35%), Gaps = 35/211 (16%)
Query: 110 KKQPTGASLVLQVSYTPLPGAVPLFP-PPTPLEPSPTLPDLDVVAGGG---QSRAETWSL 165
K++P A Q +P P A P+ PTP P PT Q ++ +SL
Sbjct: 852 KEEPKKA----QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSL 907
Query: 166 LSDSTMDTRYSGKKWPAPTDTG------GEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPR 219
S D S P T TG ++ L +P GPGAP
Sbjct: 908 NLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA 967
Query: 220 KLPSRPP------------PHYPG----IKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQ 263
PS+PP P P +K++ AP + KL Q ++ E +
Sbjct: 968 PAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP 1027
Query: 264 LPGVNIKPVVKVTAAGQ--TKRTRIHKGNSP 292
P IK +TA Q T++ K P
Sbjct: 1028 PP---IKDSKSLTAEPQKAVLPTKLEKSPKP 1055
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 54.3 bits (129), Expect = 1e-06
Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%)
Query: 1145 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1189
S SVS G ++PT + +D GN L ++ QAR+L D +
Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726
Query: 1190 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1235
+SDP+ V L + +VV+N +LNP W+QT+I+ I +
Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780
Query: 1236 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1289
+ ++ V ++D+D + +++F+G + S L+ PR W+PL ++ G+
Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838
Query: 1290 ASFELIQREKPAI 1302
+S Q KP++
Sbjct: 4839 SSQSSQQSPKPSV 4851
Score = 43.5 bits (101), Expect = 0.002
Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%)
Query: 1600 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1647
I+I++A L P+D NG DP++K+ + G+ V N ++ +L P + +
Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770
Query: 1648 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1686
++ +K L++T++DYD S ++ +GE ++DL +
Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812
Score = 43.1 bits (100), Expect = 0.003
Identities = 57/211 (27%), Positives = 81/211 (38%), Gaps = 39/211 (18%)
Query: 33 KKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKVPLR 90
K+RTK ++ S+NP WN+ + K I ++Q L V V D++ N FLGE + L
Sbjct: 4754 KRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDL- 4810
Query: 91 EVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPPPTP 139
S S N P K+ T G S Q S +P P + +FP P+
Sbjct: 4811 -----SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSK 4865
Query: 140 LEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWPAPTDTGGEEDTEDQGLTG 199
PT+ +S + S S S R G + + ED G
Sbjct: 4866 DMQVPTIE---------KSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAI 4916
Query: 200 DEAEPFLDQSGGPGAPTTPRKLPSRPPPHYP 230
AE + Q R P++PP H P
Sbjct: 4917 AAAEAAVQQL---------RIQPTKPPNHRP 4938
Score = 36.6 bits (83), Expect = 0.27
Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Query: 463 SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 518
+K ++K+ NP+WNQ + ++ +K + + + D+DR + ND + + +S S
Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814
Score = 34.7 bits (78), Expect = 1.0
Identities = 53/211 (25%), Positives = 74/211 (35%), Gaps = 35/211 (16%)
Query: 110 KKQPTGASLVLQVSYTPLPGAVPLFP-PPTPLEPSPTLPDLDVVAGGG---QSRAETWSL 165
K++P A Q +P P A P+ PTP P PT Q ++ +SL
Sbjct: 852 KEEPKKA----QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSL 907
Query: 166 LSDSTMDTRYSGKKWPAPTDTG------GEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPR 219
S D S P T TG ++ L +P GPGAP
Sbjct: 908 NLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA 967
Query: 220 KLPSRPP------------PHYPG----IKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQ 263
PS+PP P P +K++ AP + KL Q ++ E +
Sbjct: 968 PAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP 1027
Query: 264 LPGVNIKPVVKVTAAGQ--TKRTRIHKGNSP 292
P IK +TA Q T++ K P
Sbjct: 1028 PP---IKDSKSLTAEPQKAVLPTKLEKSPKP 1055
>gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo
sapiens]
Length = 778
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)
Query: 1176 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1235
+ + RDL AMD + SDPY HQ K+ ++ TLNP W + F+ E
Sbjct: 255 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 306
Query: 1236 AEQPPSIVVELYDHDTYGADEFMGRC 1261
E+ I + +D D D+F+GRC
Sbjct: 307 -ERGGVIDITAWDKDAGKRDDFIGRC 331
Score = 42.7 bits (99), Expect = 0.004
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 1597 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1656
+V I ++ L+ D NG DPY+K +G + + +P TL P + + F+
Sbjct: 250 IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 307
Query: 1657 LEKDLKITLYDYDLLSKDEKIGETVVDL 1684
+ IT +D D +D+ IG VDL
Sbjct: 308 RGGVIDITAWDKDAGKRDDFIGRCQVDL 335
Score = 42.4 bits (98), Expect = 0.005
Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65
++RA L +A +SDP + + T + ++NP WN+ F +++K D S
Sbjct: 411 VIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----DIHSV 466
Query: 66 LHVVVKDHETMGRNRFLGEAKVPLREV 92
L V V D + FLG+ +PL +
Sbjct: 467 LEVTVYDEDRDRSADFLGKVAIPLLSI 493
Score = 41.2 bits (95), Expect = 0.011
Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 1600 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1657
I + R L +D G DPY+K IG K V + I L PV+ E C L L
Sbjct: 44 ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 99
Query: 1658 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1691
+ L I ++DYD +D+ +G +DL L++
Sbjct: 100 REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 133
Score = 38.9 bits (89), Expect = 0.054
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%)
Query: 1581 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1640
P R FH L G +++ ++RA GL D GK DP+ + + + Y
Sbjct: 394 PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 447
Query: 1641 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1684
L P + K+F + L++T+YD D + +G+ + L
Sbjct: 448 LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 490
Score = 37.7 bits (86), Expect = 0.12
Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Query: 449 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 507
DP+V+ GK + SKI+ K NP W + + + + E + I++ D+D +D +
Sbjct: 62 DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 119
Query: 508 ATTYLSMSKI 517
+ +L ++++
Sbjct: 120 GSAFLDLTQL 129
Score = 37.7 bits (86), Expect = 0.12
Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65
L+ +L + + SDP K ++K++ ++NP W E F++ L ++G
Sbjct: 255 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGV 311
Query: 66 LHVVVKDHETMGRNRFLGEAKVPL 89
+ + D + R+ F+G +V L
Sbjct: 312 IDITAWDKDAGKRDDFIGRCQVDL 335
Score = 35.0 bits (79), Expect = 0.77
Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%)
Query: 1172 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1231
L+ + +A L A D SDP+ +V + T V LNP W++ F
Sbjct: 407 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 458
Query: 1232 PATVAEQPPSIVVELYDHDTYGADEFMGR 1260
+ + + V +YD D + +F+G+
Sbjct: 459 --NIKDIHSVLEVTVYDEDRDRSADFLGK 485
Score = 34.3 bits (77), Expect = 1.3
Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%)
Query: 1170 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1226
Y L + + + LAA D+ SDPY V F + ++ ++ LNP W++ +
Sbjct: 40 YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 96
Query: 1227 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1259
+ EP + ++++D+D D+FMG
Sbjct: 97 DHLREP---------LYIKVFDYDFGLQDDFMG 120
Score = 32.0 bits (71), Expect = 6.5
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 443 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 502
+ L DP+V+ + SKI+ KT NPQW + ++ + I D D
Sbjct: 265 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 323
Query: 503 HNDIVATTYLSMSKIS 518
+D + + +S +S
Sbjct: 324 RDDFIGRCQVDLSALS 339
>gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo
sapiens]
Length = 999
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)
Query: 1176 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1235
+ + RDL AMD + SDPY HQ K+ ++ TLNP W + F+ E
Sbjct: 476 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 527
Query: 1236 AEQPPSIVVELYDHDTYGADEFMGRC 1261
E+ I + +D D D+F+GRC
Sbjct: 528 -ERGGVIDITAWDKDAGKRDDFIGRC 552
Score = 42.7 bits (99), Expect = 0.004
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 1597 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1656
+V I ++ L+ D NG DPY+K +G + + +P TL P + + F+
Sbjct: 471 IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 528
Query: 1657 LEKDLKITLYDYDLLSKDEKIGETVVDL 1684
+ IT +D D +D+ IG VDL
Sbjct: 529 RGGVIDITAWDKDAGKRDDFIGRCQVDL 556
Score = 42.4 bits (98), Expect = 0.005
Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65
++RA L +A +SDP + + T + ++NP WN+ F +++K D S
Sbjct: 632 VIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----DIHSV 687
Query: 66 LHVVVKDHETMGRNRFLGEAKVPLREV 92
L V V D + FLG+ +PL +
Sbjct: 688 LEVTVYDEDRDRSADFLGKVAIPLLSI 714
Score = 41.2 bits (95), Expect = 0.011
Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 1600 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1657
I + R L +D G DPY+K IG K V + I L PV+ E C L L
Sbjct: 265 ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 320
Query: 1658 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1691
+ L I ++DYD +D+ +G +DL L++
Sbjct: 321 REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 354
Score = 38.9 bits (89), Expect = 0.054
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%)
Query: 1581 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1640
P R FH L G +++ ++RA GL D GK DP+ + + + Y
Sbjct: 615 PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 668
Query: 1641 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1684
L P + K+F + L++T+YD D + +G+ + L
Sbjct: 669 LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 711
Score = 37.7 bits (86), Expect = 0.12
Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Query: 449 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 507
DP+V+ GK + SKI+ K NP W + + + + E + I++ D+D +D +
Sbjct: 283 DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 340
Query: 508 ATTYLSMSKI 517
+ +L ++++
Sbjct: 341 GSAFLDLTQL 350
Score = 37.7 bits (86), Expect = 0.12
Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65
L+ +L + + SDP K ++K++ ++NP W E F++ L ++G
Sbjct: 476 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGV 532
Query: 66 LHVVVKDHETMGRNRFLGEAKVPL 89
+ + D + R+ F+G +V L
Sbjct: 533 IDITAWDKDAGKRDDFIGRCQVDL 556
Score = 35.0 bits (79), Expect = 0.77
Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%)
Query: 1172 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1231
L+ + +A L A D SDP+ +V + T V LNP W++ F
Sbjct: 628 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 679
Query: 1232 PATVAEQPPSIVVELYDHDTYGADEFMGR 1260
+ + + V +YD D + +F+G+
Sbjct: 680 --NIKDIHSVLEVTVYDEDRDRSADFLGK 706
Score = 34.3 bits (77), Expect = 1.3
Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%)
Query: 1170 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1226
Y L + + + LAA D+ SDPY V F + ++ ++ LNP W++ +
Sbjct: 261 YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 317
Query: 1227 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1259
+ EP + ++++D+D D+FMG
Sbjct: 318 DHLREP---------LYIKVFDYDFGLQDDFMG 341
Score = 32.0 bits (71), Expect = 6.5
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 443 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 502
+ L DP+V+ + SKI+ KT NPQW + ++ + I D D
Sbjct: 486 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 544
Query: 503 HNDIVATTYLSMSKIS 518
+D + + +S +S
Sbjct: 545 RDDFIGRCQVDLSALS 560
>gi|239743309 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 2 [Homo sapiens]
Length = 731
Score = 53.1 bits (126), Expect = 3e-06
Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 11/109 (10%)
Query: 1172 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1231
LRC + +ARDLA D++ SDP+ V + ++++T +VK + P W++T +E E+ E
Sbjct: 63 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET---FEFEL-QE 118
Query: 1232 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRL--AWFPL 1278
A A + VE +D D ++F+G+ + R+ + WF L
Sbjct: 119 GAMEA-----LCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRL 162
Score = 48.9 bits (115), Expect = 5e-05
Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 3/91 (3%)
Query: 2 LCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 61
L C ++ A +L ++ SDP + ++G + T ++K S P WNE FE++L+ ++
Sbjct: 63 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAME 122
Query: 62 QGSELHVVVKDHETMGRNRFLGEAKVPLREV 92
L V D + + RN FLG+ + ++ +
Sbjct: 123 ---ALCVEAWDWDLVSRNDFLGKVVIDVQRL 150
Score = 48.5 bits (114), Expect = 7e-05
Identities = 24/94 (25%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Query: 1592 GPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFEL 1651
G + C +R ++ A L PKD NG DP++++ K + + + + + P + + FE
Sbjct: 57 GARACRLRCSVLEARDLAPKDRNGTSDPFVRVRY--KGRTRETSIVKKSCYPRWNETFEF 114
Query: 1652 TCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLE 1685
+ L + +D+DL+S+++ +G+ V+D++
Sbjct: 115 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQ 148
Score = 42.4 bits (98), Expect = 0.005
Identities = 31/136 (22%), Positives = 53/136 (38%), Gaps = 18/136 (13%)
Query: 382 APLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFE 441
A L DP E+ + E +L R V A DL D
Sbjct: 33 AHLTEVDPDEEVQG-EIHLRLEVWPGARACRLRCSVLEARDLAPKD-------------- 77
Query: 442 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRL 501
+ DPFV V + G+ + I++K+ P+WN+ +M E + + DWD +
Sbjct: 78 --RNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAM-EALCVEAWDWDLV 134
Query: 502 THNDIVATTYLSMSKI 517
+ ND + + + ++
Sbjct: 135 SRNDFLGKVVIDVQRL 150
>gi|239743307 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 1 [Homo sapiens]
Length = 757
Score = 53.1 bits (126), Expect = 3e-06
Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 11/109 (10%)
Query: 1172 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1231
LRC + +ARDLA D++ SDP+ V + ++++T +VK + P W++T +E E+ E
Sbjct: 135 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET---FEFEL-QE 190
Query: 1232 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRL--AWFPL 1278
A A + VE +D D ++F+G+ + R+ + WF L
Sbjct: 191 GAMEA-----LCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRL 234
Score = 48.9 bits (115), Expect = 5e-05
Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 3/91 (3%)
Query: 2 LCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 61
L C ++ A +L ++ SDP + ++G + T ++K S P WNE FE++L+ ++
Sbjct: 135 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAME 194
Query: 62 QGSELHVVVKDHETMGRNRFLGEAKVPLREV 92
L V D + + RN FLG+ + ++ +
Sbjct: 195 ---ALCVEAWDWDLVSRNDFLGKVVIDVQRL 222
Score = 48.5 bits (114), Expect = 7e-05
Identities = 24/94 (25%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Query: 1592 GPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFEL 1651
G + C +R ++ A L PKD NG DP++++ K + + + + + P + + FE
Sbjct: 129 GARACRLRCSVLEARDLAPKDRNGTSDPFVRVRY--KGRTRETSIVKKSCYPRWNETFEF 186
Query: 1652 TCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLE 1685
+ L + +D+DL+S+++ +G+ V+D++
Sbjct: 187 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQ 220
Score = 43.1 bits (100), Expect = 0.003
Identities = 53/268 (19%), Positives = 96/268 (35%), Gaps = 60/268 (22%)
Query: 256 VQVIEGRQLPGVNIKP------VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGEL 309
++++EG+ LP +I +VKV + + K P + E +L +
Sbjct: 9 IRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPT---- 64
Query: 310 FDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYL 369
+ V+D +L D ++G+ + TI P+ G G+
Sbjct: 65 -FHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPK------------------GFSGW- 104
Query: 370 KTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDA 429
A L DP E+ + E +L R V A DL D
Sbjct: 105 ------------AHLTEVDPDEEVQG-EIHLRLEVWPGARACRLRCSVLEARDLAPKD-- 149
Query: 430 VMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCE 489
+ DPFV V + G+ + I++K+ P+WN+ +M E
Sbjct: 150 --------------RNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAM-E 194
Query: 490 KMRIRIIDWDRLTHNDIVATTYLSMSKI 517
+ + DWD ++ ND + + + ++
Sbjct: 195 ALCVEAWDWDLVSRNDFLGKVVIDVQRL 222
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,085,943
Number of Sequences: 37866
Number of extensions: 4672855
Number of successful extensions: 16641
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 150
Number of HSP's that attempted gapping in prelim test: 14824
Number of HSP's gapped (non-prelim): 1219
length of query: 2098
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1980
effective length of database: 13,779,330
effective search space: 27283073400
effective search space used: 27283073400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.