BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|195976773 dysferlin isoform 5 [Homo sapiens] (2088 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|195976773 dysferlin isoform 5 [Homo sapiens] 4299 0.0 gi|195976769 dysferlin isoform 6 [Homo sapiens] 4289 0.0 gi|195976779 dysferlin isoform 1 [Homo sapiens] 4283 0.0 gi|195976756 dysferlin isoform 10 [Homo sapiens] 4249 0.0 gi|195976777 dysferlin isoform 3 [Homo sapiens] 4246 0.0 gi|195976758 dysferlin isoform 11 [Homo sapiens] 4238 0.0 gi|195976821 dysferlin isoform 2 [Homo sapiens] 4235 0.0 gi|195976764 dysferlin isoform 14 [Homo sapiens] 4232 0.0 gi|195976775 dysferlin isoform 4 [Homo sapiens] 4229 0.0 gi|195976766 dysferlin isoform 7 [Homo sapiens] 4219 0.0 gi|195976754 dysferlin isoform 9 [Homo sapiens] 4195 0.0 gi|4503431 dysferlin isoform 8 [Homo sapiens] 4184 0.0 gi|195976762 dysferlin isoform 13 [Homo sapiens] 4179 0.0 gi|195976760 dysferlin isoform 12 [Homo sapiens] 4168 0.0 gi|19718759 myoferlin isoform b [Homo sapiens] 2385 0.0 gi|7305053 myoferlin isoform a [Homo sapiens] 2377 0.0 gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens] 1437 0.0 gi|35493868 otoferlin isoform b [Homo sapiens] 726 0.0 gi|35493853 otoferlin isoform c [Homo sapiens] 723 0.0 gi|34740331 otoferlin isoform a [Homo sapiens] 723 0.0 gi|119120884 fer-1-like 6 [Homo sapiens] 720 0.0 gi|35493860 otoferlin isoform d [Homo sapiens] 719 0.0 gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens] 711 0.0 gi|4759026 RAS protein activator like 1 [Homo sapiens] 65 5e-10 gi|14149680 extended synaptotagmin-like protein 1 [Homo sapiens] 57 2e-07 gi|150170670 piccolo isoform 2 [Homo sapiens] 54 1e-06 gi|150378539 piccolo isoform 1 [Homo sapiens] 54 1e-06 gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo... 54 2e-06 gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom... 54 2e-06 gi|239743309 PREDICTED: similar to calcium-promoted Ras inactiva... 53 3e-06 >gi|195976773 dysferlin isoform 5 [Homo sapiens] Length = 2088 Score = 4299 bits (11151), Expect = 0.0 Identities = 2088/2088 (100%), Positives = 2088/2088 (100%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180 Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP Sbjct: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240 Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG Sbjct: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300 Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE Sbjct: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360 Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF Sbjct: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420 Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY Sbjct: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480 Query: 481 LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR 540 LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR Sbjct: 481 LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR 540 Query: 541 GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF 600 GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF Sbjct: 541 GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF 600 Query: 601 EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE 660 EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE Sbjct: 601 EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE 660 Query: 661 TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA 720 TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA Sbjct: 661 TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA 720 Query: 721 THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI 780 THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI Sbjct: 721 THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI 780 Query: 781 VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR 840 VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR Sbjct: 781 VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR 840 Query: 841 VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL 900 VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL Sbjct: 841 VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL 900 Query: 901 PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT 960 PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT Sbjct: 901 PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT 960 Query: 961 DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM 1020 DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM Sbjct: 961 DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM 1020 Query: 1021 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR 1080 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR Sbjct: 1021 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR 1080 Query: 1081 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH 1140 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH Sbjct: 1081 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH 1140 Query: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1200 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE Sbjct: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1200 Query: 1201 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS 1260 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS Sbjct: 1201 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS 1260 Query: 1261 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA 1320 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA Sbjct: 1261 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA 1320 Query: 1321 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR 1380 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR Sbjct: 1321 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR 1380 Query: 1381 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG 1440 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG Sbjct: 1381 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG 1440 Query: 1441 EDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCG 1500 EDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCG Sbjct: 1441 EDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCG 1500 Query: 1501 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY 1560 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY Sbjct: 1501 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY 1560 Query: 1561 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV 1620 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV Sbjct: 1561 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV 1620 Query: 1621 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS 1680 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS Sbjct: 1621 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS 1680 Query: 1681 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE 1740 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE Sbjct: 1681 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE 1740 Query: 1741 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK 1800 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK Sbjct: 1741 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK 1800 Query: 1801 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1860 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ Sbjct: 1801 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1860 Query: 1861 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1920 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD Sbjct: 1861 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1920 Query: 1921 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV 1980 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV Sbjct: 1921 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV 1980 Query: 1981 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY 2040 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY Sbjct: 1981 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY 2040 Query: 2041 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2088 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS Sbjct: 2041 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2088 >gi|195976769 dysferlin isoform 6 [Homo sapiens] Length = 2102 Score = 4289 bits (11123), Expect = 0.0 Identities = 2087/2102 (99%), Positives = 2088/2102 (99%), Gaps = 14/2102 (0%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180 Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP Sbjct: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240 Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG Sbjct: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300 Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE Sbjct: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360 Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF Sbjct: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420 Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY Sbjct: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480 Query: 481 LSMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 526 LSMSKISAPGGEIE +DDYLGFLPTFGPCYINLYGSPREFTGFPDPY Sbjct: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540 Query: 527 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 586 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY Sbjct: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600 Query: 587 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 646 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV Sbjct: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660 Query: 647 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 706 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG Sbjct: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720 Query: 707 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 766 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL Sbjct: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780 Query: 767 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 826 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP Sbjct: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840 Query: 827 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 886 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL Sbjct: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900 Query: 887 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 946 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR Sbjct: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960 Query: 947 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1006 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP Sbjct: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020 Query: 1007 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1066 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF Sbjct: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080 Query: 1067 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1126 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR Sbjct: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140 Query: 1127 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1186 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW Sbjct: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200 Query: 1187 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1246 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP Sbjct: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260 Query: 1247 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1306 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY Sbjct: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320 Query: 1307 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1366 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN Sbjct: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380 Query: 1367 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1426 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS Sbjct: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440 Query: 1427 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1486 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW Sbjct: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1500 Query: 1487 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1546 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED Sbjct: 1501 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1560 Query: 1547 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1606 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK Sbjct: 1561 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1620 Query: 1607 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1666 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK Sbjct: 1621 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1680 Query: 1667 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1726 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT Sbjct: 1681 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1740 Query: 1727 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1786 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI Sbjct: 1741 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1800 Query: 1787 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1846 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI Sbjct: 1801 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1860 Query: 1847 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1906 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT Sbjct: 1861 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1920 Query: 1907 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1966 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS Sbjct: 1921 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1980 Query: 1967 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2026 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP Sbjct: 1981 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2040 Query: 2027 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2086 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP Sbjct: 2041 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100 Query: 2087 FS 2088 FS Sbjct: 2101 FS 2102 >gi|195976779 dysferlin isoform 1 [Homo sapiens] Length = 2119 Score = 4283 bits (11109), Expect = 0.0 Identities = 2088/2119 (98%), Positives = 2088/2119 (98%), Gaps = 31/2119 (1%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180 Query: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209 DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240 Query: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300 Query: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360 Query: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420 Query: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480 Query: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 509 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540 Query: 510 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 569 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR Sbjct: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600 Query: 570 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 629 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF Sbjct: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660 Query: 630 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 689 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST Sbjct: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720 Query: 690 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 749 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH Sbjct: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780 Query: 750 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 809 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN Sbjct: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840 Query: 810 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 869 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY Sbjct: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900 Query: 870 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 929 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM Sbjct: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960 Query: 930 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 989 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD Sbjct: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020 Query: 990 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1049 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA Sbjct: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080 Query: 1050 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1109 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD Sbjct: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140 Query: 1110 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1169 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL Sbjct: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200 Query: 1170 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1229 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR Sbjct: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260 Query: 1230 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1289 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES Sbjct: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320 Query: 1290 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1349 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG Sbjct: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380 Query: 1350 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1409 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI Sbjct: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440 Query: 1410 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1469 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN Sbjct: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1500 Query: 1470 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1529 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF Sbjct: 1501 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1560 Query: 1530 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1589 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR Sbjct: 1561 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1620 Query: 1590 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1649 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK Sbjct: 1621 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1680 Query: 1650 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1709 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL Sbjct: 1681 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1740 Query: 1710 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1769 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV Sbjct: 1741 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1800 Query: 1770 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1829 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR Sbjct: 1801 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1860 Query: 1830 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1889 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE Sbjct: 1861 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1920 Query: 1890 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1949 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK Sbjct: 1921 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1980 Query: 1950 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2009 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP Sbjct: 1981 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2040 Query: 2010 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2069 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA Sbjct: 2041 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2100 Query: 2070 IFIYAFPNYAAMKLVKPFS 2088 IFIYAFPNYAAMKLVKPFS Sbjct: 2101 IFIYAFPNYAAMKLVKPFS 2119 >gi|195976756 dysferlin isoform 10 [Homo sapiens] Length = 2087 Score = 4249 bits (11019), Expect = 0.0 Identities = 2067/2088 (98%), Positives = 2071/2088 (99%), Gaps = 1/2088 (0%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179 Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP Sbjct: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239 Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG Sbjct: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299 Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE Sbjct: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359 Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF Sbjct: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419 Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY Sbjct: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479 Query: 481 LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR 540 LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR Sbjct: 480 LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR 539 Query: 541 GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF 600 GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF Sbjct: 540 GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF 599 Query: 601 EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE 660 EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE Sbjct: 600 EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE 659 Query: 661 TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA 720 TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA Sbjct: 660 TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA 719 Query: 721 THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI 780 THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI Sbjct: 720 THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI 779 Query: 781 VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR 840 VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR Sbjct: 780 VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR 839 Query: 841 VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL 900 VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL Sbjct: 840 VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL 899 Query: 901 PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT 960 PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT Sbjct: 900 PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT 959 Query: 961 DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM 1020 DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM Sbjct: 960 DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM 1019 Query: 1021 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR 1080 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR Sbjct: 1020 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR 1079 Query: 1081 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH 1140 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH Sbjct: 1080 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH 1139 Query: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1200 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE Sbjct: 1140 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1199 Query: 1201 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS 1260 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS Sbjct: 1200 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS 1259 Query: 1261 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA 1320 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA Sbjct: 1260 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA 1319 Query: 1321 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR 1380 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR Sbjct: 1320 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR 1379 Query: 1381 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG 1440 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG Sbjct: 1380 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG 1439 Query: 1441 EDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCG 1500 EDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCG Sbjct: 1440 EDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCG 1499 Query: 1501 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY 1560 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY Sbjct: 1500 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY 1559 Query: 1561 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV 1620 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV Sbjct: 1560 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV 1619 Query: 1621 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS 1680 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS Sbjct: 1620 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS 1679 Query: 1681 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE 1740 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE Sbjct: 1680 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE 1739 Query: 1741 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK 1800 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK Sbjct: 1740 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK 1799 Query: 1801 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1860 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ Sbjct: 1800 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1859 Query: 1861 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1920 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD Sbjct: 1860 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1919 Query: 1921 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV 1980 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV Sbjct: 1920 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV 1979 Query: 1981 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY 2040 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY Sbjct: 1980 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY 2039 Query: 2041 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2088 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS Sbjct: 2040 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2087 >gi|195976777 dysferlin isoform 3 [Homo sapiens] Length = 2067 Score = 4246 bits (11011), Expect = 0.0 Identities = 2067/2088 (98%), Positives = 2067/2088 (98%), Gaps = 21/2088 (1%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180 Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP Sbjct: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240 Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG Sbjct: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300 Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE Sbjct: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360 Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF Sbjct: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420 Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY Sbjct: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480 Query: 481 LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR 540 LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR Sbjct: 481 LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR 540 Query: 541 GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF 600 GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF Sbjct: 541 GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF 600 Query: 601 EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE 660 EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE Sbjct: 601 EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE 660 Query: 661 TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA 720 TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA Sbjct: 661 TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA 720 Query: 721 THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI 780 THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI Sbjct: 721 THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI 780 Query: 781 VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR 840 VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR Sbjct: 781 VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR 840 Query: 841 VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL 900 VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL Sbjct: 841 VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL 900 Query: 901 PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT 960 PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT Sbjct: 901 PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT 960 Query: 961 DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM 1020 DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM Sbjct: 961 DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM 1020 Query: 1021 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR 1080 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR Sbjct: 1021 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR 1080 Query: 1081 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH 1140 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH Sbjct: 1081 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH 1140 Query: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1200 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE Sbjct: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1200 Query: 1201 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS 1260 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS Sbjct: 1201 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS 1260 Query: 1261 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA 1320 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA Sbjct: 1261 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA 1320 Query: 1321 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR 1380 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR Sbjct: 1321 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR 1380 Query: 1381 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG 1440 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG Sbjct: 1381 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG 1440 Query: 1441 EDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCG 1500 EDVLIDIDDKEPLIPIQ EEEFIDWWSKFFASIGEREKCG Sbjct: 1441 EDVLIDIDDKEPLIPIQ---------------------EEEFIDWWSKFFASIGEREKCG 1479 Query: 1501 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY 1560 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY Sbjct: 1480 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY 1539 Query: 1561 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV 1620 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV Sbjct: 1540 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV 1599 Query: 1621 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS 1680 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS Sbjct: 1600 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS 1659 Query: 1681 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE 1740 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE Sbjct: 1660 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE 1719 Query: 1741 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK 1800 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK Sbjct: 1720 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK 1779 Query: 1801 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1860 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ Sbjct: 1780 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1839 Query: 1861 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1920 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD Sbjct: 1840 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1899 Query: 1921 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV 1980 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV Sbjct: 1900 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV 1959 Query: 1981 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY 2040 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY Sbjct: 1960 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY 2019 Query: 2041 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2088 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS Sbjct: 2020 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2067 >gi|195976758 dysferlin isoform 11 [Homo sapiens] Length = 2101 Score = 4238 bits (10991), Expect = 0.0 Identities = 2066/2102 (98%), Positives = 2071/2102 (98%), Gaps = 15/2102 (0%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179 Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP Sbjct: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239 Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG Sbjct: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299 Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE Sbjct: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359 Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF Sbjct: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419 Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY Sbjct: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479 Query: 481 LSMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 526 LSMSKISAPGGEIE +DDYLGFLPTFGPCYINLYGSPREFTGFPDPY Sbjct: 480 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 539 Query: 527 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 586 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY Sbjct: 540 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 599 Query: 587 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 646 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV Sbjct: 600 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 659 Query: 647 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 706 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG Sbjct: 660 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 719 Query: 707 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 766 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL Sbjct: 720 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 779 Query: 767 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 826 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP Sbjct: 780 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 839 Query: 827 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 886 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL Sbjct: 840 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 899 Query: 887 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 946 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR Sbjct: 900 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 959 Query: 947 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1006 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP Sbjct: 960 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1019 Query: 1007 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1066 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF Sbjct: 1020 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1079 Query: 1067 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1126 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR Sbjct: 1080 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1139 Query: 1127 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1186 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW Sbjct: 1140 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1199 Query: 1187 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1246 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP Sbjct: 1200 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1259 Query: 1247 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1306 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY Sbjct: 1260 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1319 Query: 1307 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1366 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN Sbjct: 1320 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1379 Query: 1367 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1426 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS Sbjct: 1380 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1439 Query: 1427 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1486 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW Sbjct: 1440 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1499 Query: 1487 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1546 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED Sbjct: 1500 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1559 Query: 1547 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1606 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK Sbjct: 1560 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1619 Query: 1607 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1666 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK Sbjct: 1620 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1679 Query: 1667 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1726 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT Sbjct: 1680 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1739 Query: 1727 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1786 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI Sbjct: 1740 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1799 Query: 1787 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1846 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI Sbjct: 1800 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1859 Query: 1847 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1906 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT Sbjct: 1860 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1919 Query: 1907 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1966 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS Sbjct: 1920 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1979 Query: 1967 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2026 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP Sbjct: 1980 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2039 Query: 2027 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2086 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP Sbjct: 2040 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2099 Query: 2087 FS 2088 FS Sbjct: 2100 FS 2101 >gi|195976821 dysferlin isoform 2 [Homo sapiens] Length = 2081 Score = 4235 bits (10983), Expect = 0.0 Identities = 2066/2102 (98%), Positives = 2067/2102 (98%), Gaps = 35/2102 (1%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180 Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP Sbjct: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240 Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG Sbjct: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300 Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE Sbjct: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360 Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF Sbjct: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420 Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY Sbjct: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480 Query: 481 LSMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 526 LSMSKISAPGGEIE +DDYLGFLPTFGPCYINLYGSPREFTGFPDPY Sbjct: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540 Query: 527 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 586 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY Sbjct: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600 Query: 587 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 646 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV Sbjct: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660 Query: 647 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 706 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG Sbjct: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720 Query: 707 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 766 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL Sbjct: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780 Query: 767 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 826 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP Sbjct: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840 Query: 827 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 886 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL Sbjct: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900 Query: 887 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 946 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR Sbjct: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960 Query: 947 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1006 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP Sbjct: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020 Query: 1007 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1066 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF Sbjct: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080 Query: 1067 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1126 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR Sbjct: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140 Query: 1127 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1186 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW Sbjct: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200 Query: 1187 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1246 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP Sbjct: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260 Query: 1247 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1306 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY Sbjct: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320 Query: 1307 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1366 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN Sbjct: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380 Query: 1367 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1426 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS Sbjct: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440 Query: 1427 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1486 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ EEEFIDWW Sbjct: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ---------------------EEEFIDWW 1479 Query: 1487 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1546 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED Sbjct: 1480 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1539 Query: 1547 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1606 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK Sbjct: 1540 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1599 Query: 1607 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1666 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK Sbjct: 1600 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1659 Query: 1667 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1726 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT Sbjct: 1660 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1719 Query: 1727 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1786 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI Sbjct: 1720 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1779 Query: 1787 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1846 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI Sbjct: 1780 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1839 Query: 1847 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1906 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT Sbjct: 1840 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1899 Query: 1907 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1966 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS Sbjct: 1900 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1959 Query: 1967 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2026 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP Sbjct: 1960 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2019 Query: 2027 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2086 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP Sbjct: 2020 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2079 Query: 2087 FS 2088 FS Sbjct: 2080 FS 2081 >gi|195976764 dysferlin isoform 14 [Homo sapiens] Length = 2118 Score = 4232 bits (10977), Expect = 0.0 Identities = 2067/2119 (97%), Positives = 2071/2119 (97%), Gaps = 32/2119 (1%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179 Query: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209 DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT Sbjct: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239 Query: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF Sbjct: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299 Query: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD Sbjct: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359 Query: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA Sbjct: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419 Query: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL Sbjct: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479 Query: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 509 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY Sbjct: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 539 Query: 510 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 569 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR Sbjct: 540 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 599 Query: 570 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 629 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF Sbjct: 600 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 659 Query: 630 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 689 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST Sbjct: 660 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 719 Query: 690 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 749 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH Sbjct: 720 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 779 Query: 750 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 809 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN Sbjct: 780 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 839 Query: 810 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 869 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY Sbjct: 840 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 899 Query: 870 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 929 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM Sbjct: 900 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 959 Query: 930 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 989 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD Sbjct: 960 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1019 Query: 990 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1049 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA Sbjct: 1020 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1079 Query: 1050 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1109 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD Sbjct: 1080 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1139 Query: 1110 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1169 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL Sbjct: 1140 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1199 Query: 1170 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1229 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR Sbjct: 1200 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1259 Query: 1230 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1289 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES Sbjct: 1260 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1319 Query: 1290 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1349 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG Sbjct: 1320 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1379 Query: 1350 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1409 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI Sbjct: 1380 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1439 Query: 1410 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1469 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN Sbjct: 1440 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1499 Query: 1470 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1529 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF Sbjct: 1500 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1559 Query: 1530 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1589 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR Sbjct: 1560 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1619 Query: 1590 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1649 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK Sbjct: 1620 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1679 Query: 1650 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1709 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL Sbjct: 1680 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1739 Query: 1710 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1769 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV Sbjct: 1740 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1799 Query: 1770 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1829 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR Sbjct: 1800 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1859 Query: 1830 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1889 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE Sbjct: 1860 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1919 Query: 1890 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1949 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK Sbjct: 1920 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1979 Query: 1950 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2009 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP Sbjct: 1980 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2039 Query: 2010 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2069 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA Sbjct: 2040 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2099 Query: 2070 IFIYAFPNYAAMKLVKPFS 2088 IFIYAFPNYAAMKLVKPFS Sbjct: 2100 IFIYAFPNYAAMKLVKPFS 2118 >gi|195976775 dysferlin isoform 4 [Homo sapiens] Length = 2098 Score = 4229 bits (10969), Expect = 0.0 Identities = 2067/2119 (97%), Positives = 2067/2119 (97%), Gaps = 52/2119 (2%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180 Query: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209 DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240 Query: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300 Query: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360 Query: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420 Query: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480 Query: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 509 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540 Query: 510 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 569 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR Sbjct: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600 Query: 570 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 629 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF Sbjct: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660 Query: 630 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 689 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST Sbjct: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720 Query: 690 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 749 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH Sbjct: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780 Query: 750 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 809 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN Sbjct: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840 Query: 810 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 869 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY Sbjct: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900 Query: 870 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 929 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM Sbjct: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960 Query: 930 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 989 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD Sbjct: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020 Query: 990 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1049 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA Sbjct: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080 Query: 1050 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1109 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD Sbjct: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140 Query: 1110 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1169 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL Sbjct: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200 Query: 1170 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1229 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR Sbjct: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260 Query: 1230 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1289 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES Sbjct: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320 Query: 1290 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1349 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG Sbjct: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380 Query: 1350 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1409 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI Sbjct: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440 Query: 1410 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1469 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ Sbjct: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ------------ 1488 Query: 1470 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1529 EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF Sbjct: 1489 ---------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1539 Query: 1530 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1589 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR Sbjct: 1540 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1599 Query: 1590 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1649 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK Sbjct: 1600 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1659 Query: 1650 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1709 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL Sbjct: 1660 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1719 Query: 1710 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1769 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV Sbjct: 1720 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1779 Query: 1770 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1829 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR Sbjct: 1780 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1839 Query: 1830 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1889 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE Sbjct: 1840 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1899 Query: 1890 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1949 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK Sbjct: 1900 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1959 Query: 1950 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2009 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP Sbjct: 1960 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2019 Query: 2010 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2069 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA Sbjct: 2020 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2079 Query: 2070 IFIYAFPNYAAMKLVKPFS 2088 IFIYAFPNYAAMKLVKPFS Sbjct: 2080 IFIYAFPNYAAMKLVKPFS 2098 >gi|195976766 dysferlin isoform 7 [Homo sapiens] Length = 2112 Score = 4219 bits (10941), Expect = 0.0 Identities = 2066/2133 (96%), Positives = 2067/2133 (96%), Gaps = 66/2133 (3%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180 Query: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209 DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240 Query: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300 Query: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360 Query: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420 Query: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480 Query: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 495 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE + Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540 Query: 496 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 555 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS Sbjct: 541 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600 Query: 556 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 615 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC Sbjct: 601 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660 Query: 616 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 675 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG Sbjct: 661 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720 Query: 676 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 735 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL Sbjct: 721 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780 Query: 736 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 795 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR Sbjct: 781 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840 Query: 796 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 855 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN Sbjct: 841 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900 Query: 856 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 915 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG Sbjct: 901 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960 Query: 916 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 975 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC Sbjct: 961 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020 Query: 976 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1035 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR Sbjct: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080 Query: 1036 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1095 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA Sbjct: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140 Query: 1096 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1155 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD Sbjct: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200 Query: 1156 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1215 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL Sbjct: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260 Query: 1216 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1275 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP Sbjct: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320 Query: 1276 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1335 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ Sbjct: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380 Query: 1336 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1395 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN Sbjct: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440 Query: 1396 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1455 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP Sbjct: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500 Query: 1456 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1515 IQ EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT Sbjct: 1501 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1539 Query: 1516 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1575 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF Sbjct: 1540 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1599 Query: 1576 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1635 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF Sbjct: 1600 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1659 Query: 1636 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1695 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS Sbjct: 1660 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1719 Query: 1696 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1755 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE Sbjct: 1720 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1779 Query: 1756 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1815 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR Sbjct: 1780 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1839 Query: 1816 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1875 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF Sbjct: 1840 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1899 Query: 1876 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1935 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL Sbjct: 1900 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1959 Query: 1936 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 1995 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM Sbjct: 1960 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2019 Query: 1996 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2055 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI Sbjct: 2020 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2079 Query: 2056 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2088 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS Sbjct: 2080 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2112 >gi|195976754 dysferlin isoform 9 [Homo sapiens] Length = 2066 Score = 4195 bits (10879), Expect = 0.0 Identities = 2046/2088 (97%), Positives = 2050/2088 (98%), Gaps = 22/2088 (1%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179 Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP Sbjct: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239 Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG Sbjct: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299 Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE Sbjct: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359 Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF Sbjct: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419 Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY Sbjct: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479 Query: 481 LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR 540 LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR Sbjct: 480 LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR 539 Query: 541 GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF 600 GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF Sbjct: 540 GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF 599 Query: 601 EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE 660 EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE Sbjct: 600 EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE 659 Query: 661 TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA 720 TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA Sbjct: 660 TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA 719 Query: 721 THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI 780 THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI Sbjct: 720 THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI 779 Query: 781 VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR 840 VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR Sbjct: 780 VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR 839 Query: 841 VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL 900 VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL Sbjct: 840 VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL 899 Query: 901 PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT 960 PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT Sbjct: 900 PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT 959 Query: 961 DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM 1020 DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM Sbjct: 960 DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM 1019 Query: 1021 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR 1080 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR Sbjct: 1020 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR 1079 Query: 1081 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH 1140 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH Sbjct: 1080 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH 1139 Query: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1200 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE Sbjct: 1140 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1199 Query: 1201 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS 1260 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS Sbjct: 1200 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS 1259 Query: 1261 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA 1320 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA Sbjct: 1260 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA 1319 Query: 1321 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR 1380 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR Sbjct: 1320 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR 1379 Query: 1381 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG 1440 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG Sbjct: 1380 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG 1439 Query: 1441 EDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCG 1500 EDVLIDIDDKEPLIPIQ EEEFIDWWSKFFASIGEREKCG Sbjct: 1440 EDVLIDIDDKEPLIPIQ---------------------EEEFIDWWSKFFASIGEREKCG 1478 Query: 1501 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY 1560 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY Sbjct: 1479 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY 1538 Query: 1561 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV 1620 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV Sbjct: 1539 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV 1598 Query: 1621 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS 1680 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS Sbjct: 1599 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS 1658 Query: 1681 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE 1740 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE Sbjct: 1659 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE 1718 Query: 1741 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK 1800 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK Sbjct: 1719 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK 1778 Query: 1801 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1860 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ Sbjct: 1779 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1838 Query: 1861 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1920 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD Sbjct: 1839 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1898 Query: 1921 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV 1980 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV Sbjct: 1899 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV 1958 Query: 1981 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY 2040 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY Sbjct: 1959 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY 2018 Query: 2041 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2088 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS Sbjct: 2019 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2066 >gi|4503431 dysferlin isoform 8 [Homo sapiens] Length = 2080 Score = 4184 bits (10851), Expect = 0.0 Identities = 2045/2102 (97%), Positives = 2050/2102 (97%), Gaps = 36/2102 (1%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179 Query: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP Sbjct: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239 Query: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG Sbjct: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299 Query: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE Sbjct: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359 Query: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF Sbjct: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419 Query: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY Sbjct: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479 Query: 481 LSMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 526 LSMSKISAPGGEIE +DDYLGFLPTFGPCYINLYGSPREFTGFPDPY Sbjct: 480 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 539 Query: 527 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 586 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY Sbjct: 540 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 599 Query: 587 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 646 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV Sbjct: 600 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 659 Query: 647 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 706 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG Sbjct: 660 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 719 Query: 707 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 766 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL Sbjct: 720 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 779 Query: 767 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 826 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP Sbjct: 780 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 839 Query: 827 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 886 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL Sbjct: 840 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 899 Query: 887 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 946 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR Sbjct: 900 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 959 Query: 947 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1006 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP Sbjct: 960 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1019 Query: 1007 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1066 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF Sbjct: 1020 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1079 Query: 1067 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1126 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR Sbjct: 1080 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1139 Query: 1127 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1186 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW Sbjct: 1140 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1199 Query: 1187 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1246 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP Sbjct: 1200 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1259 Query: 1247 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1306 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY Sbjct: 1260 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1319 Query: 1307 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1366 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN Sbjct: 1320 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1379 Query: 1367 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1426 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS Sbjct: 1380 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1439 Query: 1427 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1486 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ EEEFIDWW Sbjct: 1440 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ---------------------EEEFIDWW 1478 Query: 1487 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1546 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED Sbjct: 1479 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1538 Query: 1547 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1606 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK Sbjct: 1539 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1598 Query: 1607 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1666 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK Sbjct: 1599 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1658 Query: 1667 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1726 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT Sbjct: 1659 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1718 Query: 1727 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1786 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI Sbjct: 1719 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1778 Query: 1787 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1846 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI Sbjct: 1779 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1838 Query: 1847 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1906 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT Sbjct: 1839 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1898 Query: 1907 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1966 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS Sbjct: 1899 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1958 Query: 1967 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2026 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP Sbjct: 1959 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2018 Query: 2027 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2086 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP Sbjct: 2019 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2078 Query: 2087 FS 2088 FS Sbjct: 2079 FS 2080 >gi|195976762 dysferlin isoform 13 [Homo sapiens] Length = 2097 Score = 4179 bits (10837), Expect = 0.0 Identities = 2046/2119 (96%), Positives = 2050/2119 (96%), Gaps = 53/2119 (2%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179 Query: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209 DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT Sbjct: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239 Query: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF Sbjct: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299 Query: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD Sbjct: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359 Query: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA Sbjct: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419 Query: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL Sbjct: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479 Query: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 509 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY Sbjct: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 539 Query: 510 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 569 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR Sbjct: 540 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 599 Query: 570 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 629 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF Sbjct: 600 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 659 Query: 630 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 689 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST Sbjct: 660 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 719 Query: 690 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 749 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH Sbjct: 720 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 779 Query: 750 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 809 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN Sbjct: 780 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 839 Query: 810 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 869 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY Sbjct: 840 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 899 Query: 870 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 929 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM Sbjct: 900 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 959 Query: 930 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 989 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD Sbjct: 960 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1019 Query: 990 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1049 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA Sbjct: 1020 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1079 Query: 1050 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1109 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD Sbjct: 1080 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1139 Query: 1110 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1169 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL Sbjct: 1140 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1199 Query: 1170 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1229 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR Sbjct: 1200 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1259 Query: 1230 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1289 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES Sbjct: 1260 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1319 Query: 1290 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1349 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG Sbjct: 1320 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1379 Query: 1350 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1409 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI Sbjct: 1380 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1439 Query: 1410 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1469 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ Sbjct: 1440 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ------------ 1487 Query: 1470 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1529 EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF Sbjct: 1488 ---------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1538 Query: 1530 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1589 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR Sbjct: 1539 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1598 Query: 1590 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1649 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK Sbjct: 1599 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1658 Query: 1650 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1709 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL Sbjct: 1659 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1718 Query: 1710 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1769 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV Sbjct: 1719 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1778 Query: 1770 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1829 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR Sbjct: 1779 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1838 Query: 1830 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1889 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE Sbjct: 1839 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1898 Query: 1890 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1949 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK Sbjct: 1899 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1958 Query: 1950 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2009 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP Sbjct: 1959 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2018 Query: 2010 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2069 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA Sbjct: 2019 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2078 Query: 2070 IFIYAFPNYAAMKLVKPFS 2088 IFIYAFPNYAAMKLVKPFS Sbjct: 2079 IFIYAFPNYAAMKLVKPFS 2097 >gi|195976760 dysferlin isoform 12 [Homo sapiens] Length = 2111 Score = 4168 bits (10809), Expect = 0.0 Identities = 2045/2133 (95%), Positives = 2050/2133 (96%), Gaps = 67/2133 (3%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL Sbjct: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL Sbjct: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119 Query: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA Sbjct: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179 Query: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209 DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT Sbjct: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239 Query: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF Sbjct: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299 Query: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD Sbjct: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359 Query: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA Sbjct: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419 Query: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL Sbjct: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479 Query: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 495 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE + Sbjct: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 539 Query: 496 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 555 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS Sbjct: 540 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 599 Query: 556 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 615 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC Sbjct: 600 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 659 Query: 616 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 675 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG Sbjct: 660 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 719 Query: 676 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 735 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL Sbjct: 720 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 779 Query: 736 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 795 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR Sbjct: 780 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 839 Query: 796 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 855 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN Sbjct: 840 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 899 Query: 856 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 915 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG Sbjct: 900 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 959 Query: 916 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 975 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC Sbjct: 960 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1019 Query: 976 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1035 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR Sbjct: 1020 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1079 Query: 1036 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1095 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA Sbjct: 1080 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1139 Query: 1096 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1155 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD Sbjct: 1140 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1199 Query: 1156 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1215 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL Sbjct: 1200 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1259 Query: 1216 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1275 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP Sbjct: 1260 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1319 Query: 1276 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1335 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ Sbjct: 1320 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1379 Query: 1336 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1395 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN Sbjct: 1380 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1439 Query: 1396 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1455 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP Sbjct: 1440 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1499 Query: 1456 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1515 IQ EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT Sbjct: 1500 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1538 Query: 1516 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1575 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF Sbjct: 1539 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1598 Query: 1576 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1635 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF Sbjct: 1599 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1658 Query: 1636 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1695 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS Sbjct: 1659 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1718 Query: 1696 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1755 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE Sbjct: 1719 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1778 Query: 1756 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1815 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR Sbjct: 1779 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1838 Query: 1816 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1875 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF Sbjct: 1839 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1898 Query: 1876 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1935 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL Sbjct: 1899 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1958 Query: 1936 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 1995 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM Sbjct: 1959 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2018 Query: 1996 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2055 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI Sbjct: 2019 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2078 Query: 2056 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2088 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS Sbjct: 2079 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2111 >gi|19718759 myoferlin isoform b [Homo sapiens] Length = 2048 Score = 2385 bits (6181), Expect = 0.0 Identities = 1181/2113 (55%), Positives = 1517/2113 (71%), Gaps = 94/2113 (4%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 ML ++ ASN+P K + DP+ S+ F+ KK+TK + N +NPVWNE E+DL+GIPL Sbjct: 1 MLRVIVESASNIPKTKFGK-PDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPL 59 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLV 119 D S L ++VKD ET+G+N+ +G A V L+++ S S + LL+ K Q TGA++ Sbjct: 60 DFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATID 119 Query: 120 LQVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSG 179 L + Y P P P P L P++P + GEED D+ + Sbjct: 120 LVIGYDP-----PSAPHPNDLS-GPSVPGMG----GDGEEDEGDEDRLDNAVR------- 162 Query: 180 GPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIK 239 GPG K P +R SR++LS+KPQDFQIRV+VIEGRQL G NI+ Sbjct: 163 GPGP-----KGPVGTVSEAQLARRLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIR 217 Query: 240 PVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALL 299 PVVKV GQT RTRI +GN+P F+E F+N+ +P EL DE I I V +S SLR D L+ Sbjct: 218 PVVKVHVCGQTHRTRIKRGNNPFFDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLM 277 Query: 300 GEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPS 359 GEF++DVG +Y EP HA +RKWLLL+DP+D S+G++GY+K S+ VLG GDE P ER+D Sbjct: 278 GEFKIDVGFVYDEPGHAVMRKWLLLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERRDRD 337 Query: 360 EDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDP 419 D +D+ESNLL P G+ALR F LK++RAED+PQMDDA VK+IFG ++KKNLVDP Sbjct: 338 NDSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDP 397 Query: 420 FVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATT 479 FVEVSFAGK +C+ I+EK ANP+WNQ + L FPS+CEK+++ I DWDRLT ND+V TT Sbjct: 398 FVEVSFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTT 457 Query: 480 YLSMSKISAPGGEIEV---DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEG 536 YL +SKI+A GGE+EV + +GF+PTFGPCY+NLYGSPRE+TGFPDPY ELNTGKGEG Sbjct: 458 YLHLSKIAASGGEVEVNTGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNTGKGEG 517 Query: 537 VAYRGRLLLSLETKLVE-HSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVD 595 VAYRGR+L+ L T L + ++K+E + DD+L VEKY RRRKYSL A F+SATMLQDV Sbjct: 518 VAYRGRILVELATFLEKTPPDKKLEPISNDDLLVVEKYQRRRKYSLSAVFHSATMLQDVG 577 Query: 596 DAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDI 655 +AIQFEVSIGNYGNKFD TC PLASTTQYSRAVFDG +YYYLPW + KPVV L+SYWEDI Sbjct: 578 EAIQFEVSIGNYGNKFDTTCKPLASTTQYSRAVFDGNYYYYLPWAHTKPVVTLTSYWEDI 637 Query: 656 SHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIH 715 SHR++ N LL +A+RL+ +E + ++ + + L +L DE+I L Sbjct: 638 SHRLDAVNTLLAMAERLQTNIEALKSGIQGKIPANQLAELWLKLIDEVIEDTRYTLPLTE 697 Query: 716 ETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQN 775 + T LD + +LR+ LSQI EAA+ ++ +++ + L + EDWL +L L EEPQN Sbjct: 698 GKANVTVLDTQIRKLRSRSLSQIHEAAVRMRSEATDVKSTLAEIEDWLDKLMQLTEEPQN 757 Query: 776 SLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARM 835 S+PDI+IWM++G+KR+AY R+PAHQVL+S G N GK CGK QTIFLKYP EK G ++ Sbjct: 758 SMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGENASGKYCGKTQTIFLKYPQEKNNGPKV 817 Query: 836 PVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT-YPKFSDV 894 PV++RV +W GLS EK+FN FAEG +VFAE YEN+ + G WGT+GL KFSDV Sbjct: 818 PVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQA--LMFGKWGTSGLVGRHKFSDV 875 Query: 895 TGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIY 954 TGKIKL ++ F P GW W G+W V PE++LL + DAGH F +EV++N++R PGG W Sbjct: 876 TGKIKLKREFFLPPKGWEWEGEWIVDPERSLLTEADAGHTEFTDEVYQNESRYPGGDWKP 935 Query: 955 MSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHW 1014 D YTD NG+K ++ CP GW+WED+ WS D+NRAVDE+GWEY ITIPP+ KPK W Sbjct: 936 AEDTYTDANGDKAASPSELTCPPGWEWEDDAWSYDINRAVDEKGWEYGITIPPDHKPKSW 995 Query: 1015 VPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEG-EGWEYASLFGWKFHLEYRKT 1073 V AEKMY+THRRRR VR R++DL+Q + E + EGWEYASL GWKFH + R + Sbjct: 996 VAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELQDQEGWEYASLIGWKFHWKQRSS 1055 Query: 1074 DAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVM----DDKS-EDSMSVSTLSFGVNRPT 1128 D FRRRRWRR+M P E G AA+F LEGALG D+KS E +T FG N P Sbjct: 1056 DTFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGDEKSLEKQKHSATTVFGANTPI 1115 Query: 1129 ISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQ 1188 +SC FD YHLRCY+YQAR+L A+DKDSFSDPYA + FLH+S+ T ++ +TLNPTWDQ Sbjct: 1116 VSCNFDRVYIYHLRCYVYQARNLLALDKDSFSDPYAHICFLHRSKTTEIIHSTLNPTWDQ 1175 Query: 1189 TLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQP------SLERMPRL 1242 T+IF E+EI+GEP TV + PP +++EL+D+D G DEF+GR I P ++ P+L Sbjct: 1176 TIIFDEVEIYGEPQTVLQNPPKVIMELFDNDQVGKDEFLGRSIFSPVVKLNSEMDITPKL 1235 Query: 1243 AWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQRE 1302 W P+ G + G++L + ELI R K + ++LP PPQR Sbjct: 1236 LWHPVMNGDKACGDVLVTAELILRGK---------------------DGSNLPILPPQRA 1274 Query: 1303 ANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLR 1362 N+YMVPQ I+P +Q TAIEILAWGLRNMK++Q+A+I+SPSLVVECGG+ V+S VI+NL+ Sbjct: 1275 PNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSPSLVVECGGERVESVVIKNLK 1334 Query: 1363 KNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSA 1422 K PNF LFM+V LP+EELY PP+ +KVID+RQFGR+PVVGQCTI L+ F CDPY+ Sbjct: 1335 KTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTIERLDRFRCDPYAG 1394 Query: 1423 -ESPSPQGGPDDVSLLS--PGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHE 1479 E PQ SLLS P D++I+++D +PL+ +L + E Sbjct: 1395 KEDIVPQ---LKASLLSAPPCRDIVIEMEDTKPLLASKLTE-----------------KE 1434 Query: 1480 EEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGK 1539 EE +DWWSKF+AS GE EKCG Y++K + LK+Y+ +LENV FEGL+DF +TFKLYRGK Sbjct: 1435 EEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLTDFSDTFKLYRGK 1494 Query: 1540 TQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQ 1599 + +E EDPSV+GEFKG F+IYPLP+DP++P PPRQF +L PQEC VRIYIVR LQ Sbjct: 1495 S-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQECTVRIYIVRGLELQ 1553 Query: 1600 PKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYD 1659 P+D NG CDPYIKI++GKK + D+D+YIP TL PVFG+M+EL+C LP EKDLKI++YDYD Sbjct: 1554 PQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEKDLKISVYDYD 1613 Query: 1660 LLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRV 1719 ++DEK+GET++DLENR LS+FG+ CG+P+ YCVSG N WRDQLRP+QLL + Sbjct: 1614 TFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPTQLLQNVARFKGF 1673 Query: 1720 KAPVYRTD--RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRP 1777 P+ D R+ + ++YS++E EA +I + HLG EERLALH+L+ QGLVPEHVE+R Sbjct: 1674 PQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRTQGLVPEHVETRT 1733 Query: 1778 LYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLS 1837 L+S QP+I QGKLQMWVD+FPK+LG PGPPFNITPR+A++++LR IIWNT+DVILD+ S Sbjct: 1734 LHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVIIWNTKDVILDEKS 1793 Query: 1838 LTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKK 1897 +TGE+MSDIYVKGW+ G EE+KQKTDVHYRSL GEGNFNWRF+FPFDYLPAEQ+C +AKK Sbjct: 1794 ITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDYLPAEQLCIVAKK 1853 Query: 1898 DAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD 1957 + FW +D+TE +IP R++ QIWDNDKFS DD+LG L+LDL PAK+ +KC LD + D Sbjct: 1854 EHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAKSPEKCRLDMIPD 1913 Query: 1958 --AFHP--EWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQG 2013 A +P SLFEQK++KGWWPC AE+ +++AGK+EMTLEI+ E E +ERPAG+G Sbjct: 1914 LKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEILNEKEADERPAGKG 1973 Query: 2014 RDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIY 2073 RDEPNMNPKL+ P RP+TSFLWFT+P KTMKFI+WRRF+W II + L ILLLF+A+ +Y Sbjct: 1974 RDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLFLLILLLFVAVLLY 2033 Query: 2074 AFPNYAAMKLVKP 2086 + PNY +MK+VKP Sbjct: 2034 SLPNYLSMKIVKP 2046 >gi|7305053 myoferlin isoform a [Homo sapiens] Length = 2061 Score = 2377 bits (6161), Expect = 0.0 Identities = 1180/2126 (55%), Positives = 1516/2126 (71%), Gaps = 107/2126 (5%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 ML ++ ASN+P K + DP+ S+ F+ KK+TK + N +NPVWNE E+DL+GIPL Sbjct: 1 MLRVIVESASNIPKTKFGK-PDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPL 59 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLV 119 D S L ++VKD ET+G+N+ +G A V L+++ S S + LL+ K Q TGA++ Sbjct: 60 DFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATID 119 Query: 120 LQVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSG 179 L + Y P P P P L P++P + GEED D+ + Sbjct: 120 LVIGYDP-----PSAPHPNDLS-GPSVPGMG----GDGEEDEGDEDRLDNAVR------- 162 Query: 180 GPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIK 239 GPG K P +R SR++LS+KPQDFQIRV+VIEGRQL G NI+ Sbjct: 163 GPGP-----KGPVGTVSEAQLARRLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIR 217 Query: 240 PVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALL 299 PVVKV GQT RTRI +GN+P F+E F+N+ +P EL DE I I V +S SLR D L+ Sbjct: 218 PVVKVHVCGQTHRTRIKRGNNPFFDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLM 277 Query: 300 GEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPS 359 GEF++DVG +Y EP HA +RKWLLL+DP+D S+G++GY+K S+ VLG GDE P ER+D Sbjct: 278 GEFKIDVGFVYDEPGHAVMRKWLLLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERRDRD 337 Query: 360 EDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDP 419 D +D+ESNLL P G+ALR F LK++RAED+PQMDDA VK+IFG ++KKNLVDP Sbjct: 338 NDSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDP 397 Query: 420 FVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATT 479 FVEVSFAGK +C+ I+EK ANP+WNQ + L FPS+CEK+++ I DWDRLT ND+V TT Sbjct: 398 FVEVSFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTT 457 Query: 480 YLSMSKISAPGGEIE----------------VDDYLGFLPTFGPCYINLYGSPREFTGFP 523 YL +SKI+A GGE+E + +GF+PTFGPCY+NLYGSPRE+TGFP Sbjct: 458 YLHLSKIAASGGEVEDFSSSGTGAASYTVNTGETEVGFVPTFGPCYLNLYGSPREYTGFP 517 Query: 524 DPYTELNTGKGEGVAYRGRLLLSLETKLVE-HSEQKVEDLPADDILRVEKYLRRRKYSLF 582 DPY ELNTGKGEGVAYRGR+L+ L T L + ++K+E + DD+L VEKY RRRKYSL Sbjct: 518 DPYDELNTGKGEGVAYRGRILVELATFLEKTPPDKKLEPISNDDLLVVEKYQRRRKYSLS 577 Query: 583 AAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNV 642 A F+SATMLQDV +AIQFEVSIGNYGNKFD TC PLASTTQYSRAVFDG +YYYLPW + Sbjct: 578 AVFHSATMLQDVGEAIQFEVSIGNYGNKFDTTCKPLASTTQYSRAVFDGNYYYYLPWAHT 637 Query: 643 KPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDE 702 KPVV L+SYWEDISHR++ N LL +A+RL+ +E + ++ + + L +L DE Sbjct: 638 KPVVTLTSYWEDISHRLDAVNTLLAMAERLQTNIEALKSGIQGKIPANQLAELWLKLIDE 697 Query: 703 LIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDW 762 +I L + T LD + +LR+ LSQI EAA+ ++ +++ + L + EDW Sbjct: 698 VIEDTRYTLPLTEGKANVTVLDTQIRKLRSRSLSQIHEAAVRMRSEATDVKSTLAEIEDW 757 Query: 763 LLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIF 822 L +L L EEPQNS+PDI+IWM++G+KR+AY R+PAHQVL+S G N GK CGK QTIF Sbjct: 758 LDKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGENASGKYCGKTQTIF 817 Query: 823 LKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWG 882 LKYP EK G ++PV++RV +W GLS EK+FN FAEG +VFAE YEN+ + G WG Sbjct: 818 LKYPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQA--LMFGKWG 875 Query: 883 TTGLT-YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVF 941 T+GL KFSDVTGKIKL ++ F P GW W G+W V PE++LL + DAGH F +EV+ Sbjct: 876 TSGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGEWIVDPERSLLTEADAGHTEFTDEVY 935 Query: 942 ENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEY 1001 +N++R PGG W D YTD NG+K ++ CP GW+WED+ WS D+NRAVDE+GWEY Sbjct: 936 QNESRYPGGDWKPAEDTYTDANGDKAASPSELTCPPGWEWEDDAWSYDINRAVDEKGWEY 995 Query: 1002 SITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEG-EGWEYAS 1060 ITIPP+ KPK WV AEKMY+THRRRR VR R++DL+Q + E + EGWEYAS Sbjct: 996 GITIPPDHKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELQDQEGWEYAS 1055 Query: 1061 LFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVM----DDKS-EDSM 1115 L GWKFH + R +D FRRRRWRR+M P E G AA+F LEGALG D+KS E Sbjct: 1056 LIGWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGDEKSLEKQK 1115 Query: 1116 SVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKT 1175 +T FG N P +SC FD YHLRCY+YQAR+L A+DKDSFSDPYA + FLH+S+ T Sbjct: 1116 HSATTVFGANTPIVSCNFDRVYIYHLRCYVYQARNLLALDKDSFSDPYAHICFLHRSKTT 1175 Query: 1176 VVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQP- 1234 ++ +TLNPTWDQT+IF E+EI+GEP TV + PP +++EL+D+D G DEF+GR I P Sbjct: 1176 EIIHSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPKVIMELFDNDQVGKDEFLGRSIFSPV 1235 Query: 1235 -----SLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1289 ++ P+L W P+ G + G++L + ELI R K Sbjct: 1236 VKLNSEMDITPKLLWHPVMNGDKACGDVLVTAELILRGK--------------------- 1274 Query: 1290 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1349 + ++LP PPQR N+YMVPQ I+P +Q TAIEILAWGLRNMK++Q+A+I+SPSLVVECG Sbjct: 1275 DGSNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSPSLVVECG 1334 Query: 1350 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1409 G+ V+S VI+NL+K PNF LFM+V LP+EELY PP+ +KVID+RQFGR+PVVGQCTI Sbjct: 1335 GERVESVVIKNLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTI 1394 Query: 1410 RSLESFLCDPYSA-ESPSPQGGPDDVSLLS--PGEDVLIDIDDKEPLIPIQLADGLSSLA 1466 L+ F CDPY+ E PQ SLLS P D++I+++D +PL+ +L + Sbjct: 1395 ERLDRFRCDPYAGKEDIVPQ---LKASLLSAPPCRDIVIEMEDTKPLLASKLTE------ 1445 Query: 1467 PTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGL 1526 EEE +DWWSKF+AS GE EKCG Y++K + LK+Y+ +LENV FEGL Sbjct: 1446 -----------KEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGL 1494 Query: 1527 SDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQEC 1586 +DF +TFKLYRGK+ +E EDPSV+GEFKG F+IYPLP+DP++P PPRQF +L PQEC Sbjct: 1495 TDFSDTFKLYRGKS-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQEC 1553 Query: 1587 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1646 VRIYIVR LQP+D NG CDPYIKI++GKK + D+D+YIP TL PVFG+M+EL+C LP Sbjct: 1554 TVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLP 1613 Query: 1647 LEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRP 1706 EKDLKI++YDYD ++DEK+GET++DLENR LS+FG+ CG+P+ YCVSG N WRDQLRP Sbjct: 1614 QEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRP 1673 Query: 1707 SQLLHLFCQQHRVKAPVYRTD--RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQ 1764 +QLL + P+ D R+ + ++YS++E EA +I + HLG EERLALH+L+ Sbjct: 1674 TQLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILR 1733 Query: 1765 QQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCI 1824 QGLVPEHVE+R L+S QP+I QGKLQMWVD+FPK+LG PGPPFNITPR+A++++LR I Sbjct: 1734 TQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVI 1793 Query: 1825 IWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFD 1884 IWNT+DVILD+ S+TGE+MSDIYVKGW+ G EE+KQKTDVHYRSL GEGNFNWRF+FPFD Sbjct: 1794 IWNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFD 1853 Query: 1885 YLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPA 1944 YLPAEQ+C +AKK+ FW +D+TE +IP R++ QIWDNDKFS DD+LG L+LDL PA Sbjct: 1854 YLPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPA 1913 Query: 1945 KTAKKCSLDQLDD--AFHP--EWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 2000 K+ +KC LD + D A +P SLFEQK++KGWWPC AE+ +++AGK+EMTLEI+ Sbjct: 1914 KSPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEIL 1973 Query: 2001 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2060 E E +ERPAG+GRDEPNMNPKL+ P RP+TSFLWFT+P KTMKFI+WRRF+W II + Sbjct: 1974 NEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLF 2033 Query: 2061 LFILLLFLAIFIYAFPNYAAMKLVKP 2086 L ILLLF+A+ +Y+ PNY +MK+VKP Sbjct: 2034 LLILLLFVAVLLYSLPNYLSMKIVKP 2059 >gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens] Length = 2093 Score = 1437 bits (3720), Expect = 0.0 Identities = 857/2175 (39%), Positives = 1209/2175 (55%), Gaps = 277/2175 (12%) Query: 23 PVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNRFL 82 P S+ FR +KKRT+V++ + +PVWNE W L PL+ S L V ++D + + RF+ Sbjct: 21 PCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLENDSFLQVTLQDMGSQKKERFI 79 Query: 83 GEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPPPTPLE 141 G A V L+ +L PS + + LL+ +PT ++ LQV++ Sbjct: 80 GLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQVAH----------------- 122 Query: 142 PSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGI 201 + + D+ TG E+ G+T EA +KL PG Sbjct: 123 ----MSNQDI-EKTGAEDHL---GITAREA--------------ASQKLM------VPG- 153 Query: 202 KRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSP 261 T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ +TRI GN+P Sbjct: 154 ------STAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNP 207 Query: 262 LFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKW 321 FNE F N + P + FDE I I + D+G IY P H LRKW Sbjct: 208 FFNEIFFQNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKW 250 Query: 322 LLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAH 381 L L P++ +G GYLK ++ LG GD+A +++K +D + + + V + A+ Sbjct: 251 LGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAY 309 Query: 382 FCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANP 441 L ++ AEDL K V+P +EV G+ L + + +T NP Sbjct: 310 LQLFIYCAEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNP 352 Query: 442 QWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDD---- 497 WNQ +T P + ++ R++D + D + T LS+++IS+ G EIE Sbjct: 353 IWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEP 412 Query: 498 -------YLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETK 550 Y GFLP FGP ++ L+G + + + +G+AYRGR+ L L T+ Sbjct: 413 TSYTPRVYSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQ 472 Query: 551 LVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNK 610 + + + ++DL + ++ R+EK+ R+KY L F S TM+ + + I FEVSIG+YGNK Sbjct: 473 IKSYQDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNK 531 Query: 611 FDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIAD 670 D+ PL S+T YS ++DG Y+Y+PW N KPVV ++S WED+S R+ N L D Sbjct: 532 MDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRD 591 Query: 671 RLEAGLEQVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQYLY 728 RL+A L+ LK+ + +D L +L EL C +PL + P AT LD+ + Sbjct: 592 RLKANLD----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRW 647 Query: 729 QLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGD 788 QLR+ L + LA K ++ + AEDWL RL + EPQ LPD++IW++ + Sbjct: 648 QLRSLLLQE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKE 702 Query: 789 KRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLS 848 +RVAY +VPAH VLFS GA + G+ CGK+QT+FL+YP + +P +RV +W G Sbjct: 703 QRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNV 762 Query: 849 VDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDSFRP 907 D K+ +G +V+AE YEN+ K WG GL + P FSDV G LP F+P Sbjct: 763 TDSKDLQLLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTDFQP 820 Query: 908 SAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKV 967 GW W W V P++ LL D+D +EEV+ENQ R G W + TDVNG+ + Sbjct: 821 PLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPM 880 Query: 968 LPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRR 1027 +++++CP GW ++ ++W +LN AVD WEY + IPP P+ W P EK Y++ RRR Sbjct: 881 EARENVKCPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRRR 937 Query: 1028 RWVRLRRRDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTDAFR 1077 RW R+R R+ ++ H Q A+ E EGWEY + FG KFHL + FR Sbjct: 938 RWARVRFRNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQSRFR 992 Query: 1078 RRRWRRRMEPLEKTGPAAVFALEGAL----GGVMDD------------------------ 1109 RR WRRR+ P + G A +F LEG+L G V ++ Sbjct: 993 RRCWRRRLAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQ 1052 Query: 1110 ---------KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLRCYM 1145 K EDS T +G++R P I C F+ + Y L CY+ Sbjct: 1053 AMDLKYHAGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYI 1109 Query: 1146 YQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVA 1205 YQAR+L + +F P+ V FL+ SQ T ++++ PTW QTLIF + ++ P Sbjct: 1110 YQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTK 1169 Query: 1206 EQPPSIVVELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSGELL 1258 E PP +V+EL+ D +G + GR + P + +P + W PL + + GE+L Sbjct: 1170 ESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEIL 1229 Query: 1259 ASFELI-QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQ 1317 AS ELI Q EK +P V P+ + Y +P++I+P ++ Sbjct: 1230 ASCELILQTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQPTIK 1269 Query: 1318 RTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFME 1375 R AIEILAWGLRNMK SSP L+VE G +++++ IR+ + NPNF L + Sbjct: 1270 RMAIEILAWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLT 1324 Query: 1376 VMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVS 1435 V++P EE Y P+ VKV+DN FG++ V GQ I L+ + CDP++ + P+ Sbjct: 1325 VLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK------- 1377 Query: 1436 LLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEF---IDWWSKFFAS 1492 L + +K+ D L L SS E+E+ +DWWSK F + Sbjct: 1378 --------LPTLSEKKH------QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKLFWA 1421 Query: 1493 IGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGE 1552 E + Y KD+ TLKVY+ +LE V AF+GL DFC TFKLY+ ++ D V+GE Sbjct: 1422 TDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGE 1477 Query: 1553 FKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPY 1610 FKGLF+IYP PE+P P PP QF + PQ CLVR+Y+VRA LQP+D NG CDPY Sbjct: 1478 FKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPY 1537 Query: 1611 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1670 + + +GK + ++D Y P TL+P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG T Sbjct: 1538 VILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTT 1597 Query: 1671 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDR 1728 V+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL + ++ + P++ D Sbjct: 1598 VIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDA 1657 Query: 1729 VMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE 1787 V + K++ ++ E + P H LGP +ERLAL++L QGLVPEHVE+R LYS QP I+ Sbjct: 1658 VFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGID 1716 Query: 1788 QGKLQMWVDLFPKALGRPGPPFNITPRRAR---------RFFLRCIIWNTRDVILDDLSL 1838 QGK+QMWVD+FPK LG PGP NI PR+ + R+ LRCIIW T +V L D +L Sbjct: 1717 QGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNL 1776 Query: 1839 TGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKD 1898 + EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL AE+ C ++KD Sbjct: 1777 SREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKD 1836 Query: 1899 AFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDA 1958 W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ AK+CS+ +D Sbjct: 1837 YIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMD-- 1894 Query: 1959 FHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAG 2011 P+W SLF++KTV GWWPC +G K L+GK++M+LEI++E E +PAG Sbjct: 1895 ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAG 1954 Query: 2012 QGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIF 2071 +G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F+++ I+ L L F Sbjct: 1955 RGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNF 2014 Query: 2072 IYAFPNYAAMKLVKP 2086 IY+ P+Y AM +KP Sbjct: 2015 IYSAPHYLAMSWIKP 2029 Score = 40.0 bits (92), Expect = 0.024 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%) Query: 239 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 298 +P + + KRTR+ +GN P++NETL ++L++ P E D + +T+ D S + + Sbjct: 20 RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78 Query: 299 LGEFRMDVGTIYREPRHAYLRKWLLL 324 +G + + + ++P K L L Sbjct: 79 IGLATVLLKPLLKQPSEVLFVKDLTL 104 >gi|35493868 otoferlin isoform b [Homo sapiens] Length = 1230 Score = 726 bits (1875), Expect = 0.0 Identities = 409/1057 (38%), Positives = 590/1057 (55%), Gaps = 128/1057 (12%) Query: 1127 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1186 P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW Sbjct: 201 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260 Query: 1187 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1239 DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++ Sbjct: 261 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320 Query: 1240 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1296 P+L ++ + RG+ +G+LLA+FEL+Q + + DLP Sbjct: 321 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360 Query: 1297 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1353 P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V Sbjct: 361 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420 Query: 1354 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1413 QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL Sbjct: 421 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480 Query: 1414 SFLCDPYSAESPSPQGGPDDVSLLSPGEDV-----LIDID-DKEPLIPIQLADGLSSLAP 1467 F+ P +PS + V + P + ++ +D E ++ + +A+ Sbjct: 481 RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540 Query: 1468 TNTAS---PPSSPHEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1506 + P +E +DWWSK+FASI ++E G LE+ Sbjct: 541 KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600 Query: 1507 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1529 D LKVY +LE+ F+ D+ Sbjct: 601 SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658 Query: 1530 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1579 +TF L RGKT ++ TE+ ++G FKG +Y PLPED + F + Sbjct: 659 LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718 Query: 1580 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1639 + P LVR+Y+VRA L P D NGK DPYI I +GK + D++NYI L PVFGK F Sbjct: 719 SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778 Query: 1640 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1699 ++ + P+E L + +YD+DL+ D+ IGET +DLENR SK A CG+ QTY G N Sbjct: 779 DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838 Query: 1700 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1757 WRD ++PSQ+L C+ +V P + RV ++ ++ EIE N P +E Sbjct: 839 WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895 Query: 1758 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1809 +AL L+ LVPEHVE+RPL +P +P IEQG+L++WVD+FP + PG P Sbjct: 896 VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955 Query: 1810 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1868 +I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V+GW+ G +E KQ TDVHY S Sbjct: 956 DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015 Query: 1869 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1928 L GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE KIPAR+ QIWD D FS DD Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075 Query: 1929 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 1987 FLG+++LDLNR P+ AKTAK+C+++ VS+F+QK VKGWWP +A E ++ Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134 Query: 1988 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2047 L GK+E L ++ E E+ P G R+EP+ LE P RPDTSF+WF +P K+ ++ L Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTSFIWFLNPLKSARYFL 1191 Query: 2048 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2084 W +RW ++ ++L +LLL LA+F+Y+ P Y K++ Sbjct: 1192 WHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1228 Score = 87.4 bits (215), Expect = 1e-16 Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%) Query: 701 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 755 +EL GC + L D + S+ T LD+ + L + + A L+ + + Sbjct: 18 EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77 Query: 756 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 815 L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C Sbjct: 78 LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136 Query: 816 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 854 K++T+FLK P ++ G A VQ +V+ LW GLS KEF Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178 Score = 33.9 bits (76), Expect = 1.7 Identities = 13/37 (35%), Positives = 21/37 (56%) Query: 409 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 445 F ++ L DPF V F + C+++L +T P W+Q Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262 >gi|35493853 otoferlin isoform c [Homo sapiens] Length = 1307 Score = 723 bits (1867), Expect = 0.0 Identities = 418/1084 (38%), Positives = 593/1084 (54%), Gaps = 162/1084 (14%) Query: 1127 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1186 P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW Sbjct: 258 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 317 Query: 1187 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1239 DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++ Sbjct: 318 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 377 Query: 1240 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1296 P+L ++ + RG+ +G+LLA+FEL+Q + + DLP Sbjct: 378 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 417 Query: 1297 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1353 P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V Sbjct: 418 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 477 Query: 1354 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1413 QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL Sbjct: 478 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 537 Query: 1414 SFLCDPYSAESPS--------------PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLA 1459 F+ P +PS GG S S GE V+ EP +PI+ Sbjct: 538 RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGS---SSHSTGEVVVT----MEPEVPIKKL 590 Query: 1460 DGLSSLAPTNTA----------------------SPPSSPHEEEFIDWWSKFFASIG--- 1494 + + L T+ A P +E +DWWSK+FASI Sbjct: 591 ETMVKLDATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMK 650 Query: 1495 ----EREKCGSYLEKD-------------------------------------------- 1506 ++E G LE+ Sbjct: 651 EQLRQQEPSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEK 710 Query: 1507 ----FDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFK 1558 D LKVY +LE+ F+ D+ +TF L RGKT ++ TE+ ++G FKG Sbjct: 711 KKPKIDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLC 768 Query: 1559 IY--PLPEDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIK 1612 +Y PLPED + F + + P LVR+Y+VRA L P D NGK DPYI Sbjct: 769 VYKVPLPEDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIA 828 Query: 1613 ISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVV 1672 I +GK + D++NYI L PVFGK F++ + P+E L + +YD+DL+ D+ IGET + Sbjct: 829 IRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKI 888 Query: 1673 DLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMF 1731 DLENR SK A CG+ QTY G N WRD ++PSQ+L C+ +V P + RV Sbjct: 889 DLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKV 948 Query: 1732 QDKEYS-IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPL 1782 ++ ++ EIE N P +E +AL L+ LVPEHVE+RPL +P Sbjct: 949 ANRVFTGPSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPD 1005 Query: 1783 QPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGE 1841 +P IEQG+L++WVD+FP + PG P +I+PR+ +++ LR IIWNT +V+L DD TGE Sbjct: 1006 KPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGE 1065 Query: 1842 KMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFW 1901 K SDI+V+GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+ I+KK++ + Sbjct: 1066 KSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMF 1125 Query: 1902 RLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHP 1961 D+TE KIPAR+ QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++ Sbjct: 1126 SWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDV 1185 Query: 1962 EWFVSLFEQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMN 2020 VS+F+QK VKGWWP +A E ++ L GK+E L ++ E E+ P G R+EP+ Sbjct: 1186 P-LVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD-- 1242 Query: 2021 PKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAA 2080 LE P RPDTSF+WF +P K+ ++ LW +RW ++ ++L +LLL LA+F+Y+ P Y Sbjct: 1243 -PLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLV 1301 Query: 2081 MKLV 2084 K++ Sbjct: 1302 KKIL 1305 Score = 91.3 bits (225), Expect = 9e-18 Identities = 71/211 (33%), Positives = 110/211 (52%), Gaps = 21/211 (9%) Query: 652 WEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQ-- 709 W I+H ++Q E GL + +K + S + + + +EL GC + Sbjct: 38 WPSITHTPDSQ----------EEGLNDIQEMIKTEKSYPE--RRLRGVLEELSCGCCRFL 85 Query: 710 PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAALEQAEDWLLRL 766 L D + S+ T LD+ + L + + A L+ + + L +++L +L Sbjct: 86 SLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKL 145 Query: 767 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 826 R LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C K++T+FLK P Sbjct: 146 RFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDCAKVKTLFLKLP 204 Query: 827 MEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 854 ++ G A VQ +V+ LW GLS KEF Sbjct: 205 GKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 235 Score = 33.9 bits (76), Expect = 1.7 Identities = 13/37 (35%), Positives = 21/37 (56%) Query: 409 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 445 F ++ L DPF V F + C+++L +T P W+Q Sbjct: 283 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 319 >gi|34740331 otoferlin isoform a [Homo sapiens] Length = 1997 Score = 723 bits (1867), Expect = 0.0 Identities = 418/1084 (38%), Positives = 593/1084 (54%), Gaps = 162/1084 (14%) Query: 1127 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1186 P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW Sbjct: 948 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 1007 Query: 1187 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1239 DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++ Sbjct: 1008 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 1067 Query: 1240 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1296 P+L ++ + RG+ +G+LLA+FEL+Q + + DLP Sbjct: 1068 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 1107 Query: 1297 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1353 P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V Sbjct: 1108 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 1167 Query: 1354 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1413 QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL Sbjct: 1168 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 1227 Query: 1414 SFLCDPYSAESPS--------------PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLA 1459 F+ P +PS GG S S GE V+ EP +PI+ Sbjct: 1228 RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGS---SSHSTGEVVVT----MEPEVPIKKL 1280 Query: 1460 DGLSSLAPTNTA----------------------SPPSSPHEEEFIDWWSKFFASIG--- 1494 + + L T+ A P +E +DWWSK+FASI Sbjct: 1281 ETMVKLDATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMK 1340 Query: 1495 ----EREKCGSYLEKD-------------------------------------------- 1506 ++E G LE+ Sbjct: 1341 EQLRQQEPSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEK 1400 Query: 1507 ----FDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFK 1558 D LKVY +LE+ F+ D+ +TF L RGKT ++ TE+ ++G FKG Sbjct: 1401 KKPKIDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLC 1458 Query: 1559 IY--PLPEDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIK 1612 +Y PLPED + F + + P LVR+Y+VRA L P D NGK DPYI Sbjct: 1459 VYKVPLPEDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIA 1518 Query: 1613 ISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVV 1672 I +GK + D++NYI L PVFGK F++ + P+E L + +YD+DL+ D+ IGET + Sbjct: 1519 IRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKI 1578 Query: 1673 DLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMF 1731 DLENR SK A CG+ QTY G N WRD ++PSQ+L C+ +V P + RV Sbjct: 1579 DLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKV 1638 Query: 1732 QDKEYS-IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPL 1782 ++ ++ EIE N P +E +AL L+ LVPEHVE+RPL +P Sbjct: 1639 ANRVFTGPSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPD 1695 Query: 1783 QPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGE 1841 +P IEQG+L++WVD+FP + PG P +I+PR+ +++ LR IIWNT +V+L DD TGE Sbjct: 1696 KPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGE 1755 Query: 1842 KMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFW 1901 K SDI+V+GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+ I+KK++ + Sbjct: 1756 KSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMF 1815 Query: 1902 RLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHP 1961 D+TE KIPAR+ QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++ Sbjct: 1816 SWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDV 1875 Query: 1962 EWFVSLFEQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMN 2020 VS+F+QK VKGWWP +A E ++ L GK+E L ++ E E+ P G R+EP+ Sbjct: 1876 P-LVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD-- 1932 Query: 2021 PKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAA 2080 LE P RPDTSF+WF +P K+ ++ LW +RW ++ ++L +LLL LA+F+Y+ P Y Sbjct: 1933 -PLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLV 1991 Query: 2081 MKLV 2084 K++ Sbjct: 1992 KKIL 1995 Score = 396 bits (1018), Expect = e-109 Identities = 293/931 (31%), Positives = 464/931 (49%), Gaps = 117/931 (12%) Query: 20 RSDPVASLTFRGVKKRTKVIKNSVNPV-WNEGFEWDLKGIPLDQGSELHVVVKDHETMGR 78 R D +A +TFRG ++V++N + ++E F W + +D+ L + V ++ + Sbjct: 16 RGDRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVAS-SIDRNEMLEIQVFNYSKVFS 74 Query: 79 NRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPPPT 138 N+ +G ++ L++V+ + + L+D SL ++V Y G V + Sbjct: 75 NKLIGTFRMVLQKVVEESHVEVTDT--LIDDNNAIIKTSLCVEVRYQATDGTVGSWDDGD 132 Query: 139 PL-------------EPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPF---LDQSGGPG 182 L E LP + GE+ G + A P Sbjct: 133 FLGDESLQEEEKDSQETDGLLPGSRPSSRPPGEKSFRRAGRSVFSAMKLGKNRSHKEEPQ 192 Query: 183 APTTPRKLPSRPPPHYP----------------------GIKRKRSAPTSRKLLS-DKPQ 219 P P L H + KRS P + S +P Sbjct: 193 RPDEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTTNVSNKRSKPDIKMEPSAGRPM 252 Query: 220 DFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNETLFFNLFDSPGEL 278 D+Q+ + VIE RQL G+N+ PVV V K T + + N P +NE F+ SP + Sbjct: 253 DYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVM 312 Query: 279 FDEPIFITVVDSRSL-RTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGY 337 FD+ I I+V+ S++L R+ L+G F+MDVGT+Y +P H + KW +LSDPDD S+G +GY Sbjct: 313 FDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISSGLKGY 372 Query: 338 LKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGV--ALRGAHFCLKVFRAEDLPQM 395 +K + V+G GD K D++DIE NLL P GV + A F +K++RAE LP+M Sbjct: 373 VKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRM 432 Query: 396 DDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPS 455 + ++M NVK+ F E+ K+LVDP+V+V FAG+ + + + + P WN+ + +FP Sbjct: 433 NTSLMANVKKAFIGEN--KDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPP 490 Query: 456 MCEKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYG 514 +C++M+++I D D++ ND+ + T ++ + KIS G + GFLPT GP ++N+YG Sbjct: 491 LCKRMKVQIRDSDKV--NDVAIGTHFIDLRKISNDGDK-------GFLPTLGPAWVNMYG 541 Query: 515 SPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYL 574 S R +T D + +LN G GEGV++R RLLL L ++V+ S +L + ++VE+ Sbjct: 542 STRNYT-LLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSN---PELTSSTEVQVEQAT 597 Query: 575 --------RRRKYSLFAAFYSATML--QDVDDAIQFEVSIGNYGNKFDMTCLP------- 617 + ++ LF AF A+M+ ++ D I FEV+IGNYGN+ D P Sbjct: 598 PISESCAGKMEEFFLFGAFLEASMIDRRNGDKPITFEVTIGNYGNEVDGLSRPQRPRPRK 657 Query: 618 --------------------------LASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSY 651 S+T R +Y++LP+ KP + + S+ Sbjct: 658 EPGDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVTDRNYFHLPYLERKPCIYIKSW 717 Query: 652 WEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQ-- 709 W D R+ N + IAD+LE GL + +K + S + + + +EL GC + Sbjct: 718 WPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYP--ERRLRGVLEELSCGCCRFL 775 Query: 710 PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAA--LALKLGHSELPAALEQAEDWLLRL 766 L D + S+ T LD+ + L + + A L ++ + L +++L +L Sbjct: 776 SLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKL 835 Query: 767 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 826 R LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C K++T+FLK P Sbjct: 836 RFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDCAKVKTLFLKLP 894 Query: 827 MEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 854 ++ G A VQ +V+ LW GLS KEF Sbjct: 895 GKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 925 Score = 33.9 bits (76), Expect = 1.7 Identities = 13/37 (35%), Positives = 21/37 (56%) Query: 409 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 445 F ++ L DPF V F + C+++L +T P W+Q Sbjct: 973 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 1009 Score = 32.3 bits (72), Expect = 5.0 Identities = 13/35 (37%), Positives = 21/35 (60%) Query: 1161 DPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1195 DPY V F Q KT V K++ P W++ ++F ++ Sbjct: 453 DPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDL 487 >gi|119120884 fer-1-like 6 [Homo sapiens] Length = 1857 Score = 720 bits (1858), Expect = 0.0 Identities = 406/1082 (37%), Positives = 585/1082 (54%), Gaps = 145/1082 (13%) Query: 1117 VSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTV 1176 +S+ G N P + ++ + + LR +MYQAR L A D + SDP+A V+FL Q T Sbjct: 804 MSSKGAGTNHPPSNLLYQEQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSHCQTTK 863 Query: 1177 VVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL 1236 ++ TL+PTW+Q L+F ++ + G+ +AE PP +VVELYD D G E++G + P + Sbjct: 864 IISQTLSPTWNQMLLFNDLVLHGDVKELAESPPLVVVELYDSDAVGKPEYLGATVAAPVV 923 Query: 1237 E------RMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1290 + PRL + P+ G+ G+LLA FEL+Q + +P Sbjct: 924 KLADQDYEPPRLCYHPIFCGNLSGGDLLAVFELLQVPPSGLQGLP--------------- 968 Query: 1291 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1350 P PP IY VP NI+P L + +E+L WG+R MK QL ++ P ++ECGG Sbjct: 969 ----PVEPPDI-TQIYPVPANIRPVLSKYRVEVLFWGVREMKKVQLLSVDRPQALIECGG 1023 Query: 1351 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1410 Q V+SCVI++ + NPNF I EV LP EL PP+++ V+D R FGR +VG TI Sbjct: 1024 QGVKSCVIQSYKNNPNFSIQADAFEVELPENELLHPPLSICVVDWRAFGRSTLVGTYTIN 1083 Query: 1411 SLESFLCDPYSAESPSPQ-------------------GGPDDVSLLSPGEDVLIDID--- 1448 L+ FLC +P Q G S P + + +D++ Sbjct: 1084 YLKQFLCKLREPLAPITQVDGTQPGHDISDSLTATESSGAHSSSQDPPADHIYVDVEPPP 1143 Query: 1449 -------DKEPLIPIQLADGLSSLAPTNTASPPSSPHE---------------------- 1479 +P I + + D L P +T P + Sbjct: 1144 TVVPDSAQAQPAILVDVPDSSPMLEPEHTPVAQEPPKDGKPKDPRKPSRRSTKRRKRTIA 1203 Query: 1480 ----EEFIDWWSKFFASI-------------------------------GEREKCGSYLE 1504 E IDWWSK++AS+ G ++K L+ Sbjct: 1204 DESAENVIDWWSKYYASLKKAQKAKERNPKGKKGNTEAKPDEVVVDIEDGPKKKKDKMLK 1263 Query: 1505 K--------DFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEET---EDPSVIGEF 1553 K + L++YD LE+ F D+ TF+L+RGK+ E+ + VIG+F Sbjct: 1264 KKPKDDGIPNLAILQIYDGDLES--EFNNFEDWVKTFELFRGKSTEDDHGLDGDRVIGKF 1321 Query: 1554 KGLFKIYPLPEDPAIPMPPRQFHQ--LAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYI 1611 KG F IY P+D + + Q + P L+R+YIV AF L P DP+GK DPYI Sbjct: 1322 KGSFCIYKSPQDSSSEDSGQLRIQQGIPPNHPVTVLIRVYIVAAFNLSPADPDGKSDPYI 1381 Query: 1612 KISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETV 1671 I +GK + D+D YIP L PVFG+ FE+ T P E L I +YD+D++ D+ IGET Sbjct: 1382 VIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSILIYDHDMIGTDDLIGETK 1441 Query: 1672 VDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMF 1731 +DLENR SK A CGL Y + G N WRD +P+++L C+ +++ P + ++ Sbjct: 1442 IDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYFHPGKIQI 1501 Query: 1732 QDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPLQ 1783 ++ +S + I + + E LAL VL LVPEH+E+RPLY + Sbjct: 1502 GNQVFSGKTIFTEEDTDETVESYEH-LALKVLHSWEDIPEVGCRLVPEHIETRPLYHKDK 1560 Query: 1784 PDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSL-TGEK 1842 P +EQG+LQMWVD+FPK + +PGPP +I+PRR + + LR IWNT DVIL+D ++ TG+K Sbjct: 1561 PGMEQGRLQMWVDMFPKDMPQPGPPVDISPRRPKGYELRVTIWNTEDVILEDENIFTGQK 1620 Query: 1843 MSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWR 1902 SDIYVKGW+ G E+ KQ+TDVHY SL GEGNFNWRF+FPF YLPAE+ I K++ + Sbjct: 1621 SSDIYVKGWLKGLEDDKQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVITKRENIFS 1680 Query: 1903 LDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPE 1962 L+K E K PA +V Q+WD ++ S DDFLG+L+++LN P+ AK+AK C L + ++A E Sbjct: 1681 LEKMECKTPAVLVLQVWDFERLSSDDFLGTLEMNLNSFPRAAKSAKACDLAKFENA-SEE 1739 Query: 1963 WFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPK 2022 +S+F+QK V+GWWP + K L GK+E +V E E+ P G+ R EP Sbjct: 1740 TKISIFQQKRVRGWWPF----SKSKELTGKVEAEFHLVTAEEAEKNPVGKARKEPE---P 1792 Query: 2023 LEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMK 2082 L P RPDTSF WF SP+K + +++W+ ++ II+ IL IL++FL +FIY P + + Sbjct: 1793 LAKPNRPDTSFSWFMSPFKCLYYLIWKNYKKYIIIAFILIILIIFLVLFIYTLPGAISRR 1852 Query: 2083 LV 2084 +V Sbjct: 1853 IV 1854 Score = 348 bits (893), Expect = 3e-95 Identities = 236/724 (32%), Positives = 372/724 (51%), Gaps = 112/724 (15%) Query: 217 KPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNETLFFNLFDSP 275 + Q++QI + + E RQL G NI PVV + + K++ + +G NSP +NE F+ Sbjct: 79 RSQNYQIAITITEARQLVGENIDPVVTIEIGDEKKQSTVKEGTNSPFYNEYFVFDFIGPQ 138 Query: 276 GELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGAR 335 LFD+ I I+V + + + L+G F++D+GT+Y +P H + KW LL+DP D G + Sbjct: 139 VHLFDKIIKISVFHHKLIGS-VLIGSFKVDLGTVYNQPGHQFCNKWALLTDPGDIRTGTK 197 Query: 336 GYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALR--GAHFCLKVFRAEDLP 393 GYLK + V+G GD K S+ +E IE NLL P G L A F +++++AE LP Sbjct: 198 GYLKCDISVMGKGDVLKTSPK-TSDTEEPIEKNLLIPNGFPLERPWARFYVRLYKAEGLP 256 Query: 394 QMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMF 453 +M+ ++M NV + F + K+LVDPFVEVSFAG+M + + + A+P W++ + MF Sbjct: 257 KMNSSIMANVTK--AFVGDSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEMF 314 Query: 454 PSMCEKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYINL 512 P +C +++I++ WD + ND+ +AT ++ + KIS E D GFLPTFGP +INL Sbjct: 315 PPLCRRVKIQV--WDEGSMNDVALATHFIDLKKISN-----EQDGDKGFLPTFGPAWINL 367 Query: 513 YGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQ--------KVEDLPA 564 YGSPR + D Y E+N G GEGV++RGR+L+ + +++ Q K LP+ Sbjct: 368 YGSPRNHS-LMDDYQEMNEGFGEGVSFRGRILVEIAVEILSGRAQESKFSKALKELKLPS 426 Query: 565 DD------------------------------ILRVEKY--------LRRRKYSLFAAFY 586 D + VE + + ++ LF AF+ Sbjct: 427 KDKDSKSSKGKDKADKTEDGKSQQASNKTNSTEVEVESFDVPPEIVPEKNEEFLLFGAFF 486 Query: 587 SATMLQDV--DDAIQFEVSIGNYGNKFD-------------------------------M 613 ATM+ D I FEVSIGN+GN D Sbjct: 487 EATMIDRKIGDKPISFEVSIGNFGNLIDGGSHHGSKKSAESAEEDLLPLLHEGQGDVAHD 546 Query: 614 TCLPLASTTQYSRAVF--DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADR 671 +P+ASTT + + +Y YLP+ KP V S W D + R+ N L +AD Sbjct: 547 VPIPMASTTHPEKPLVTEGNRNYNYLPFEAKKPCVYFISSWGDQTFRLHWSNMLEKMADF 606 Query: 672 LEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETP---SATHLDQYLY 728 LE +E+V +K S E + + + + I+ S + + + P + T LD+ Sbjct: 607 LEESIEEVRELIK--ISQEAPEEKMKTVLSDFISRSSAFISEAEKKPKMLNQTTLDKKRL 664 Query: 729 QLRTHHLSQITEAALAL------KLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVI 782 L L + + A + KL E+ + +A++++ ++R L +EPQ+++PD+ I Sbjct: 665 TLCWQELEAMCKEAKGIIQQQKKKLSVDEM---IHEAQNFVEKIRFLVDEPQHTIPDVFI 721 Query: 783 WMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVK 842 WML ++RVAY R+ + +L+S A GK+CGK++T FLK P ++ G + ++ V Sbjct: 722 WMLSNNRRVAYARIASKDLLYS-PVAGQMGKHCGKIKTHFLKPPGKRPAGWSVQAKVDVY 780 Query: 843 LWFG 846 LW G Sbjct: 781 LWLG 784 Score = 45.4 bits (106), Expect = 6e-04 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 5/86 (5%) Query: 6 LVRASNLPSAKKDRRSDP--VASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQG 63 +V A NL A D +SDP V L +K R K I +NPV+ FE + Sbjct: 1362 IVAAFNLSPADPDGKSDPYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQAT---FPKE 1418 Query: 64 SELHVVVKDHETMGRNRFLGEAKVPL 89 S L +++ DH+ +G + +GE K+ L Sbjct: 1419 SLLSILIYDHDMIGTDDLIGETKIDL 1444 Score = 35.8 bits (81), Expect = 0.45 Identities = 16/41 (39%), Positives = 22/41 (53%) Query: 1155 DKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1195 D DP+ VSF Q +T V KN +P W + +IF E+ Sbjct: 273 DSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEM 313 Score = 35.4 bits (80), Expect = 0.59 Identities = 51/209 (24%), Positives = 80/209 (38%), Gaps = 47/209 (22%) Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNE-------GFEWDLKGI 58 + +A L +A + SDP A +TF + TK+I +++P WN+ D+K Sbjct: 832 MYQARGLIAADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQMLLFNDLVLHGDVK-- 889 Query: 59 PLDQGSELHVV-VKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQP---- 113 L + L VV + D + +G+ +LG +A P + L D +P Sbjct: 890 ELAESPPLVVVELYDSDAVGKPEYLG-------ATVAAPVVK------LADQDYEPPRLC 936 Query: 114 ---------TGASL-----VLQVSYTPLPGAVPLFPP------PTPLEPSPTLPDLDVVA 153 +G L +LQV + L G P+ PP P P P L V Sbjct: 937 YHPIFCGNLSGGDLLAVFELLQVPPSGLQGLPPVEPPDITQIYPVPANIRPVLSKYRVEV 996 Query: 154 DTGGEEDTEDQGLTGDEAEPFLDQSGGPG 182 G + + L + L + GG G Sbjct: 997 LFWGVREMKKVQLLSVDRPQALIECGGQG 1025 Score = 34.3 bits (77), Expect = 1.3 Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 8/93 (8%) Query: 411 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ-----NITLPAMFPSMCEKMRIRII 465 ++ L DPF +V+F +KI+ +T +P WNQ ++ L + E + ++ Sbjct: 841 ADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQMLLFNDLVLHGDVKELAESPPLVVV 900 Query: 466 DWDRLTHNDIVATTYLSMSKISAPGGEIEVDDY 498 + L +D V + ++AP ++ DY Sbjct: 901 E---LYDSDAVGKPEYLGATVAAPVVKLADQDY 930 >gi|35493860 otoferlin isoform d [Homo sapiens] Length = 1230 Score = 719 bits (1856), Expect = 0.0 Identities = 407/1057 (38%), Positives = 589/1057 (55%), Gaps = 128/1057 (12%) Query: 1127 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1186 P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW Sbjct: 201 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260 Query: 1187 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1239 DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++ Sbjct: 261 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320 Query: 1240 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1296 P+L ++ + RG+ +G+LLA+FEL+Q + + DLP Sbjct: 321 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360 Query: 1297 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1353 P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V Sbjct: 361 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420 Query: 1354 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1413 QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL Sbjct: 421 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480 Query: 1414 SFLCDPYSAESPSPQGGPDDVSLLSPGEDV-----LIDID-DKEPLIPIQLADGLSSLAP 1467 F+ P +PS + V + P + ++ +D E ++ + +A+ Sbjct: 481 RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540 Query: 1468 TNTAS---PPSSPHEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1506 + P +E +DWWSK+FASI ++E G LE+ Sbjct: 541 KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600 Query: 1507 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1529 D LKVY +LE+ F+ D+ Sbjct: 601 SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658 Query: 1530 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1579 +TF L RGKT ++ TE+ ++G FKG +Y PLPED + F + Sbjct: 659 LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718 Query: 1580 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1639 + P LVR+Y+VRA L P D NGK DPYI I +GK + D++NYI L PVFGK F Sbjct: 719 SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778 Query: 1640 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1699 ++ + P+E L + +YD+DL+ D+ IGET +DLENR SK A CG+ QTY G N Sbjct: 779 DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838 Query: 1700 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1757 WRD ++PSQ+L C+ +V P + RV ++ ++ EIE N P +E Sbjct: 839 WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895 Query: 1758 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1809 +AL L+ LVPEHVE+RPL +P +P IEQG+L++WVD+FP + PG P Sbjct: 896 VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955 Query: 1810 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1868 +I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V+GW+ G +E KQ TDVHY S Sbjct: 956 DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015 Query: 1869 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1928 L GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE KIPAR+ QIWD D FS DD Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075 Query: 1929 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 1987 FLG+++LDLNR P+ AKTAK+C+++ VS+F+QK VKGWWP +A E ++ Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134 Query: 1988 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2047 L GK+E L ++ E E+ P G R+EP+ LE P RPDT+F+WF +P K++K+++ Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTAFVWFLNPLKSIKYLI 1191 Query: 2048 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2084 R++W II ++ + LL L +F+Y+ P Y KL+ Sbjct: 1192 CTRYKWLIIKIVLALLGLLMLGLFLYSLPGYMVKKLL 1228 Score = 87.4 bits (215), Expect = 1e-16 Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%) Query: 701 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 755 +EL GC + L D + S+ T LD+ + L + + A L+ + + Sbjct: 18 EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77 Query: 756 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 815 L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C Sbjct: 78 LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136 Query: 816 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 854 K++T+FLK P ++ G A VQ +V+ LW GLS KEF Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178 Score = 33.9 bits (76), Expect = 1.7 Identities = 13/37 (35%), Positives = 21/37 (56%) Query: 409 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 445 F ++ L DPF V F + C+++L +T P W+Q Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262 >gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens] Length = 802 Score = 711 bits (1836), Expect = 0.0 Identities = 369/764 (48%), Positives = 498/764 (65%), Gaps = 47/764 (6%) Query: 1340 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1397 SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN Sbjct: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64 Query: 1398 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ 1457 FG++ V GQ I L+ + CDP++ + P+ L + +K+ Sbjct: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK---------------LPTLSEKKH----- 104 Query: 1458 LADGLSSLAPTNTASPPSSPHEEEF---IDWWSKFFASIGEREKCGSYLEKDFDTLKVYD 1514 D L L SS E+E+ +DWWSK F + E + Y KD+ TLKVY+ Sbjct: 105 -QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYE 160 Query: 1515 TQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQ 1574 +LE V AF+GL DFC TFKLY+ ++ D V+GEFKGLF+IYP PE+P P PP Q Sbjct: 161 CELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQ 217 Query: 1575 FHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1632 F + PQ CLVR+Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+ Sbjct: 218 FLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLD 277 Query: 1633 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1692 P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++Y Sbjct: 278 PIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSY 337 Query: 1693 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH 1750 C SGP +WRDQ+ PS LL + ++ + P++ D V + K++ ++ E + P H Sbjct: 338 CQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVH 396 Query: 1751 -LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1809 LGP +ERLAL++L QGLVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP Sbjct: 397 GLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQV 456 Query: 1810 NITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSL 1869 NI PR+ +R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL Sbjct: 457 NINPRKPKRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSL 516 Query: 1870 GGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDF 1929 GE +FNWRFIF DYL AE+ C ++KD W LD T K PAR++ Q+WDND FS DDF Sbjct: 517 TGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDF 576 Query: 1930 LGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAE 1982 LG L+LDL+ MP PA+ AK+CS+ +D P+W SLF++KTV GWWPC Sbjct: 577 LGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVL 634 Query: 1983 EGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKT 2042 +G K L+GK++M+LEI++E E +PAG+G+ EPN P L P R +TSF W SP + Sbjct: 635 DGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQN 694 Query: 2043 MKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2086 +I W+R+R+ +I F+++ I+ L L FIY+ P+Y AM +KP Sbjct: 695 FCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 738 >gi|4759026 RAS protein activator like 1 [Homo sapiens] Length = 804 Score = 65.5 bits (158), Expect = 5e-10 Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 13/127 (10%) Query: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1200 LRC++ ARDLA D SDP+A V + QS +T +K T P WD+ L E Sbjct: 135 LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVL---------E 185 Query: 1201 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQP-SLERMPRLAWF---PLTRGSQPSGE 1256 + P + VEL+D D G ++F+G P +L++ P WF P R + SG Sbjct: 186 LREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAEEDSGG 245 Query: 1257 LLASFEL 1263 L + + Sbjct: 246 NLGALRV 252 Score = 45.1 bits (105), Expect = 7e-04 Identities = 50/209 (23%), Positives = 90/209 (43%), Gaps = 20/209 (9%) Query: 1467 PTNTASPPSSPH-----EEEFIDWWSKFFASIGE--REKCGSYLEKDFDTLKVYDTQLEN 1519 P S S P+ ++E + + + S+G E+ +L DF L Y + Sbjct: 18 PAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVHLPLDFHQLAFYVLDEDT 77 Query: 1520 VEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLA 1579 V G D L R + T DP I + L ++ P D + Q+ Sbjct: 78 V----GHDDIIGKISLSR---EAITADPRGIDSWINLSRVDP---DAEVQGEICLSVQML 127 Query: 1580 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1639 G CL R +++ A L P+D +G DP+ ++ G +S+ + + I T P + ++ Sbjct: 128 EDGQGRCL-RCHVLHARDLAPRDISGTSDPFARVFWGSQSL--ETSTIKKTRFPHWDEVL 184 Query: 1640 ELTCTLPLEKDLKITLYDYDLLSKDEKIG 1668 EL L++ L+D+D++ K++ +G Sbjct: 185 ELREMPGAPSPLRVELWDWDMVGKNDFLG 213 Score = 43.5 bits (101), Expect = 0.002 Identities = 59/268 (22%), Positives = 100/268 (37%), Gaps = 64/268 (23%) Query: 223 IRVQVIEGRQLPGVNIKP------VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPG 276 + V+V+EGR LP ++ +VKV + + + P + E +L Sbjct: 7 LNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVHL----- 61 Query: 277 ELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLS--DPDDFSAGA 334 L + V+D ++ D ++G+ + I +PR + W+ LS DPD A Sbjct: 62 PLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRG--IDSWINLSRVDPD---AEV 116 Query: 335 RGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQ 394 +G + S+ +L ED + LR V A DL Sbjct: 117 QGEICLSVQML-----------------EDGQGRCLR------------CHVLHARDLAP 147 Query: 395 MDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFP 454 D + DPF V + + L + ++KT P W++ + L M P Sbjct: 148 RDIS----------------GTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREM-P 190 Query: 455 SMCEKMRIRIIDWDRLTHNDIVATTYLS 482 +R+ + DWD + ND + S Sbjct: 191 GAPSPLRVELWDWDMVGKNDFLGMVEFS 218 Score = 35.0 bits (79), Expect = 0.77 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 5/83 (6%) Query: 2 LCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEW-DLKGIPL 60 L C ++ A +L SDP A + + T IK + P W+E E ++ G P Sbjct: 135 LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGAP- 193 Query: 61 DQGSELHVVVKDHETMGRNRFLG 83 S L V + D + +G+N FLG Sbjct: 194 ---SPLRVELWDWDMVGKNDFLG 213 >gi|14149680 extended synaptotagmin-like protein 1 [Homo sapiens] Length = 1104 Score = 56.6 bits (135), Expect = 2e-07 Identities = 103/467 (22%), Positives = 175/467 (37%), Gaps = 118/467 (25%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 +L L RA +LP K ++ +P+ L+ + V + +K + ++ PVW E F + L+ Sbjct: 479 ILVVYLDRAQDLPLKKGNKEPNPMVQLSIQDVTQESKAVYSTNCPVWEEAFRFFLQD--- 535 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGA---- 116 Q EL V VKD R LG +PL +L P L +LD Q + + Sbjct: 536 PQSQELDVQVKDD---SRALTLGALTLPLARLLTAPEL-------ILDQWFQLSSSGPNS 585 Query: 117 ----SLVLQVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAE 172 LV+++ Y L + F PT+P D E Sbjct: 586 RLYMKLVMRILY--LDSSEICF---------PTVPGCPGAWDVDSE-------------- 620 Query: 173 PFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQ 232 + G PR + P + + +R+ V+E + Sbjct: 621 ---NPQRGSSVDAPPRPCHTTPDSQF-------------------GTEHVLRIHVLEAQD 658 Query: 233 L------PGVNIK----PVVKVTAAGQTKRTRIHKGN-SPLFNETLFFNLFDSPGELFDE 281 L G +K P VK+ AG++ R+ + + + +P +NE + PG+ + Sbjct: 659 LIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNEVFEVIVTSVPGQELEV 718 Query: 282 PIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTS 341 +F + L D LG ++ + T+ +L +WL L D G L Sbjct: 719 EVF-----DKDLDKDDFLGRCKVRLTTVLNS---GFLDEWLTLEDVPS------GRLHLR 764 Query: 342 LCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVF--RAEDLPQMDDAV 399 L L P R +E +E ++ N L T + A L ++ RAEDLP Sbjct: 765 LERLTP-------RPTAAELEEVLQVNSLIQTQKSAELAAALLSIYMERAEDLP------ 811 Query: 400 MDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQN 446 K+L P+ ++ +K + +T+ P W+++ Sbjct: 812 ---------LRKGTKHL-SPYATLTVGDSSHKTKTISQTSAPVWDES 848 Score = 48.1 bits (113), Expect = 9e-05 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 16/102 (15%) Query: 1135 YGNRYHLRCYMYQARDLAAMDK------DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQ 1188 +G + LR ++ +A+DL A D+ SDPY + +S ++ VV+ LNP W++ Sbjct: 643 FGTEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNE 702 Query: 1189 TLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1230 +E+ + P E VE++D D D+F+GRC Sbjct: 703 V---FEVIVTSVPGQELE------VEVFDKD-LDKDDFLGRC 734 Score = 47.0 bits (110), Expect = 2e-04 Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 10/123 (8%) Query: 1567 AIPMPPRQFHQLA-AQGPQECLVRIYIVRAFGLQPKDP------NGKCDPYIKISIGKKS 1619 ++ PPR H +Q E ++RI+++ A L KD GK DPY+K+ + +S Sbjct: 627 SVDAPPRPCHTTPDSQFGTEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRS 686 Query: 1620 VSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLL 1679 + + + L P + ++FE+ T ++L++ ++D D L KD+ +G V L L Sbjct: 687 F--RSHVVREDLNPRWNEVFEVIVTSVPGQELEVEVFDKD-LDKDDFLGRCKVRLTTVLN 743 Query: 1680 SKF 1682 S F Sbjct: 744 SGF 746 Score = 45.4 bits (106), Expect = 6e-04 Identities = 37/118 (31%), Positives = 55/118 (46%), Gaps = 18/118 (15%) Query: 1141 LRCYMYQARDLAAMDK------DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYE 1194 +R ++ AR L++ DK + SDPYA+V Q+ + V+ LNP W +T YE Sbjct: 331 IRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRLGTQTFCSRVIDEELNPQWGET---YE 387 Query: 1195 IEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPS--LERMPRLAWFPLTRG 1250 + + P I VE++D D D+F+GR L+ WFPL G Sbjct: 388 VMVHEVPG------QEIEVEVFDKDP-DKDDFLGRMKLDVGKVLQASVLDDWFPLQGG 438 Score = 42.4 bits (98), Expect = 0.005 Identities = 35/98 (35%), Positives = 53/98 (54%), Gaps = 14/98 (14%) Query: 22 DPVASLTF-----RGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD--QGSELHVVVKDHE 74 DP SL RG K+RT K +++P +NE FEW+L PLD Q +L V VK + Sbjct: 1007 DPYVSLLLLPDKNRGTKRRTSQKKRTLSPEFNERFEWEL---PLDEAQRRKLDVSVKSNS 1063 Query: 75 T-MGRNR-FLGEAKVPLREVLATPSLSASFNAPLLDTK 110 + M R R LG+ ++ L E + ++ ++ L+D K Sbjct: 1064 SFMSRERELLGKVQLDLAETDLSQGVARWYD--LMDNK 1099 Score = 37.7 bits (86), Expect = 0.12 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 7/98 (7%) Query: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60 +L + RA +LP K + P A+LT +TK I + PVW+E + ++ P Sbjct: 799 LLSIYMERAEDLPLRKGTKHLSPYATLTVGDSSHKTKTISQTSAPVWDESASFLIRK-PH 857 Query: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSL 98 + EL V E G LG +PL E+L L Sbjct: 858 TESLELQV---RGEGTG---VLGSLSLPLSELLVADQL 889 Score = 34.7 bits (78), Expect = 1.0 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 4/83 (4%) Query: 20 RSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRN 79 +SDP A + ++VI +NP W E +E + +P G E+ V V D + ++ Sbjct: 355 KSDPYALVRLGTQTFCSRVIDEELNPQWGETYEVMVHEVP---GQEIEVEVFDKDP-DKD 410 Query: 80 RFLGEAKVPLREVLATPSLSASF 102 FLG K+ + +VL L F Sbjct: 411 DFLGRMKLDVGKVLQASVLDDWF 433 Score = 33.9 bits (76), Expect = 1.7 Identities = 17/52 (32%), Positives = 23/52 (44%) Query: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIF 1192 L YM +A DL PYA ++ S KT + T P WD++ F Sbjct: 800 LSIYMERAEDLPLRKGTKHLSPYATLTVGDSSHKTKTISQTSAPVWDESASF 851 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 54.3 bits (129), Expect = 1e-06 Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%) Query: 1114 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1158 S SVS G ++PT + +D GN L ++ QAR+L D + Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726 Query: 1159 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1204 +SDP+ V L + +VV+N +LNP W+QT+I+ I + Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780 Query: 1205 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1258 + ++ V ++D+D + +++F+G + S L+ PR W+PL ++ G+ Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838 Query: 1259 ASFELIQREKPAI 1271 +S Q KP++ Sbjct: 4839 SSQSSQQSPKPSV 4851 Score = 43.5 bits (101), Expect = 0.002 Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%) Query: 1590 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1637 I+I++A L P+D NG DP++K+ + G+ V N ++ +L P + + Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770 Query: 1638 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1676 ++ +K L++T++DYD S ++ +GE ++DL + Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812 Score = 38.9 bits (89), Expect = 0.053 Identities = 39/127 (30%), Positives = 56/127 (44%), Gaps = 21/127 (16%) Query: 33 KKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKVPLR 90 K+RTK ++ S+NP WN+ + K I ++Q L V V D++ N FLGE + L Sbjct: 4754 KRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDL- 4810 Query: 91 EVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPPPTP 139 S S N P K+ T G S Q S +P P + +FP P+ Sbjct: 4811 -----SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSK 4865 Query: 140 LEPSPTL 146 PT+ Sbjct: 4866 DMQVPTI 4872 Score = 36.6 bits (83), Expect = 0.26 Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%) Query: 432 SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 487 +K ++K+ NP+WNQ + ++ +K + + + D+DR + ND + + +S S Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814 Score = 32.0 bits (71), Expect = 6.5 Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 12/123 (9%) Query: 112 QPTGASLVLQVSYTPLPGAV--PLFPPPTPLEPSPTL-PDLDVVADTGGEEDTEDQGLTG 168 QP+G + L PG V P+ PP T P+ L P TG E+ + +Q Sbjct: 334 QPSGLTKPLAQQ----PGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389 Query: 169 DEAEP-----FLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQI 223 A+P Q GP P T + +P PG++ AP K +P +I Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449 Query: 224 RVQ 226 Q Sbjct: 450 PAQ 452 Score = 32.0 bits (71), Expect = 6.5 Identities = 46/160 (28%), Positives = 56/160 (35%), Gaps = 39/160 (24%) Query: 82 LGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPP----- 136 LG AK P ++ T S S P QP G V TP P PP Sbjct: 366 LGPAKPPAQQ---TGSEKPSSEQPGPKALAQPPG------VGKTPAQQPGPAKPPTQQVG 416 Query: 137 -PTPLE-----------PSPTLPDLD------VVADTGGEEDTEDQGLTGDEAEPFLDQS 178 P PL P PT + + A G T Q TG P Q Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ-TGPTKPP--SQL 473 Query: 179 GGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKP 218 GP P + P++PPP PG + P S++ S KP Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPG----SAKPPSQQPGSTKP 509 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 54.3 bits (129), Expect = 1e-06 Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%) Query: 1114 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1158 S SVS G ++PT + +D GN L ++ QAR+L D + Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726 Query: 1159 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1204 +SDP+ V L + +VV+N +LNP W+QT+I+ I + Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780 Query: 1205 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1258 + ++ V ++D+D + +++F+G + S L+ PR W+PL ++ G+ Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838 Query: 1259 ASFELIQREKPAI 1271 +S Q KP++ Sbjct: 4839 SSQSSQQSPKPSV 4851 Score = 43.5 bits (101), Expect = 0.002 Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%) Query: 1590 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1637 I+I++A L P+D NG DP++K+ + G+ V N ++ +L P + + Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770 Query: 1638 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1676 ++ +K L++T++DYD S ++ +GE ++DL + Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812 Score = 38.9 bits (89), Expect = 0.053 Identities = 39/127 (30%), Positives = 56/127 (44%), Gaps = 21/127 (16%) Query: 33 KKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKVPLR 90 K+RTK ++ S+NP WN+ + K I ++Q L V V D++ N FLGE + L Sbjct: 4754 KRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDL- 4810 Query: 91 EVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPPPTP 139 S S N P K+ T G S Q S +P P + +FP P+ Sbjct: 4811 -----SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSK 4865 Query: 140 LEPSPTL 146 PT+ Sbjct: 4866 DMQVPTI 4872 Score = 36.6 bits (83), Expect = 0.26 Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%) Query: 432 SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 487 +K ++K+ NP+WNQ + ++ +K + + + D+DR + ND + + +S S Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814 Score = 32.0 bits (71), Expect = 6.5 Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 12/123 (9%) Query: 112 QPTGASLVLQVSYTPLPGAV--PLFPPPTPLEPSPTL-PDLDVVADTGGEEDTEDQGLTG 168 QP+G + L PG V P+ PP T P+ L P TG E+ + +Q Sbjct: 334 QPSGLTKPLAQQ----PGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389 Query: 169 DEAEP-----FLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQI 223 A+P Q GP P T + +P PG++ AP K +P +I Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449 Query: 224 RVQ 226 Q Sbjct: 450 PAQ 452 Score = 32.0 bits (71), Expect = 6.5 Identities = 46/160 (28%), Positives = 56/160 (35%), Gaps = 39/160 (24%) Query: 82 LGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPP----- 136 LG AK P ++ T S S P QP G V TP P PP Sbjct: 366 LGPAKPPAQQ---TGSEKPSSEQPGPKALAQPPG------VGKTPAQQPGPAKPPTQQVG 416 Query: 137 -PTPLE-----------PSPTLPDLD------VVADTGGEEDTEDQGLTGDEAEPFLDQS 178 P PL P PT + + A G T Q TG P Q Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ-TGPTKPP--SQL 473 Query: 179 GGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKP 218 GP P + P++PPP PG + P S++ S KP Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPG----SAKPPSQQPGSTKP 509 >gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo sapiens] Length = 778 Score = 53.9 bits (128), Expect = 2e-06 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%) Query: 1145 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1204 + + RDL AMD + SDPY HQ K+ ++ TLNP W + F+ E Sbjct: 255 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 306 Query: 1205 AEQPPSIVVELYDHDTYGADEFMGRC 1230 E+ I + +D D D+F+GRC Sbjct: 307 -ERGGVIDITAWDKDAGKRDDFIGRC 331 Score = 42.7 bits (99), Expect = 0.004 Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Query: 1587 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1646 +V I ++ L+ D NG DPY+K +G + + +P TL P + + F+ Sbjct: 250 IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 307 Query: 1647 LEKDLKITLYDYDLLSKDEKIGETVVDL 1674 + IT +D D +D+ IG VDL Sbjct: 308 RGGVIDITAWDKDAGKRDDFIGRCQVDL 335 Score = 42.4 bits (98), Expect = 0.005 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 4/87 (4%) Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65 ++RA L +A +SDP + + T + ++NP WN+ F +++K D S Sbjct: 411 VIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----DIHSV 466 Query: 66 LHVVVKDHETMGRNRFLGEAKVPLREV 92 L V V D + FLG+ +PL + Sbjct: 467 LEVTVYDEDRDRSADFLGKVAIPLLSI 493 Score = 41.2 bits (95), Expect = 0.011 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%) Query: 1590 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1647 I + R L +D G DPY+K IG K V + I L PV+ E C L L Sbjct: 44 ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 99 Query: 1648 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1681 + L I ++DYD +D+ +G +DL L++ Sbjct: 100 REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 133 Score = 38.9 bits (89), Expect = 0.053 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%) Query: 1571 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1630 P R FH L G +++ ++RA GL D GK DP+ + + + Y Sbjct: 394 PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 447 Query: 1631 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1674 L P + K+F + L++T+YD D + +G+ + L Sbjct: 448 LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 490 Score = 37.7 bits (86), Expect = 0.12 Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%) Query: 418 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 476 DP+V+ GK + SKI+ K NP W + + + + E + I++ D+D +D + Sbjct: 62 DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 119 Query: 477 ATTYLSMSKI 486 + +L ++++ Sbjct: 120 GSAFLDLTQL 129 Score = 37.7 bits (86), Expect = 0.12 Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 3/84 (3%) Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65 L+ +L + + SDP K ++K++ ++NP W E F++ L ++G Sbjct: 255 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGV 311 Query: 66 LHVVVKDHETMGRNRFLGEAKVPL 89 + + D + R+ F+G +V L Sbjct: 312 IDITAWDKDAGKRDDFIGRCQVDL 335 Score = 35.0 bits (79), Expect = 0.77 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%) Query: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1200 L+ + +A L A D SDP+ +V + T V LNP W++ F Sbjct: 407 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 458 Query: 1201 PATVAEQPPSIVVELYDHDTYGADEFMGR 1229 + + + V +YD D + +F+G+ Sbjct: 459 --NIKDIHSVLEVTVYDEDRDRSADFLGK 485 Score = 34.3 bits (77), Expect = 1.3 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%) Query: 1139 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1195 Y L + + + LAA D+ SDPY V F + ++ ++ LNP W++ + Sbjct: 40 YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 96 Query: 1196 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1228 + EP + ++++D+D D+FMG Sbjct: 97 DHLREP---------LYIKVFDYDFGLQDDFMG 120 Score = 32.0 bits (71), Expect = 6.5 Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%) Query: 412 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 471 + L DP+V+ + SKI+ KT NPQW + ++ + I D D Sbjct: 265 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 323 Query: 472 HNDIVATTYLSMSKIS 487 +D + + +S +S Sbjct: 324 RDDFIGRCQVDLSALS 339 >gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo sapiens] Length = 999 Score = 53.9 bits (128), Expect = 2e-06 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%) Query: 1145 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1204 + + RDL AMD + SDPY HQ K+ ++ TLNP W + F+ E Sbjct: 476 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 527 Query: 1205 AEQPPSIVVELYDHDTYGADEFMGRC 1230 E+ I + +D D D+F+GRC Sbjct: 528 -ERGGVIDITAWDKDAGKRDDFIGRC 552 Score = 42.7 bits (99), Expect = 0.004 Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Query: 1587 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1646 +V I ++ L+ D NG DPY+K +G + + +P TL P + + F+ Sbjct: 471 IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 528 Query: 1647 LEKDLKITLYDYDLLSKDEKIGETVVDL 1674 + IT +D D +D+ IG VDL Sbjct: 529 RGGVIDITAWDKDAGKRDDFIGRCQVDL 556 Score = 42.4 bits (98), Expect = 0.005 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 4/87 (4%) Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65 ++RA L +A +SDP + + T + ++NP WN+ F +++K D S Sbjct: 632 VIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----DIHSV 687 Query: 66 LHVVVKDHETMGRNRFLGEAKVPLREV 92 L V V D + FLG+ +PL + Sbjct: 688 LEVTVYDEDRDRSADFLGKVAIPLLSI 714 Score = 41.2 bits (95), Expect = 0.011 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%) Query: 1590 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1647 I + R L +D G DPY+K IG K V + I L PV+ E C L L Sbjct: 265 ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 320 Query: 1648 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1681 + L I ++DYD +D+ +G +DL L++ Sbjct: 321 REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 354 Score = 38.9 bits (89), Expect = 0.053 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%) Query: 1571 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1630 P R FH L G +++ ++RA GL D GK DP+ + + + Y Sbjct: 615 PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 668 Query: 1631 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1674 L P + K+F + L++T+YD D + +G+ + L Sbjct: 669 LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 711 Score = 37.7 bits (86), Expect = 0.12 Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%) Query: 418 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 476 DP+V+ GK + SKI+ K NP W + + + + E + I++ D+D +D + Sbjct: 283 DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 340 Query: 477 ATTYLSMSKI 486 + +L ++++ Sbjct: 341 GSAFLDLTQL 350 Score = 37.7 bits (86), Expect = 0.12 Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 3/84 (3%) Query: 6 LVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSE 65 L+ +L + + SDP K ++K++ ++NP W E F++ L ++G Sbjct: 476 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGV 532 Query: 66 LHVVVKDHETMGRNRFLGEAKVPL 89 + + D + R+ F+G +V L Sbjct: 533 IDITAWDKDAGKRDDFIGRCQVDL 556 Score = 35.0 bits (79), Expect = 0.77 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%) Query: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1200 L+ + +A L A D SDP+ +V + T V LNP W++ F Sbjct: 628 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 679 Query: 1201 PATVAEQPPSIVVELYDHDTYGADEFMGR 1229 + + + V +YD D + +F+G+ Sbjct: 680 --NIKDIHSVLEVTVYDEDRDRSADFLGK 706 Score = 34.3 bits (77), Expect = 1.3 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%) Query: 1139 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1195 Y L + + + LAA D+ SDPY V F + ++ ++ LNP W++ + Sbjct: 261 YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 317 Query: 1196 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1228 + EP + ++++D+D D+FMG Sbjct: 318 DHLREP---------LYIKVFDYDFGLQDDFMG 341 Score = 32.0 bits (71), Expect = 6.5 Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%) Query: 412 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 471 + L DP+V+ + SKI+ KT NPQW + ++ + I D D Sbjct: 486 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 544 Query: 472 HNDIVATTYLSMSKIS 487 +D + + +S +S Sbjct: 545 RDDFIGRCQVDLSALS 560 >gi|239743309 PREDICTED: similar to calcium-promoted Ras inactivator isoform 2 [Homo sapiens] Length = 731 Score = 53.1 bits (126), Expect = 3e-06 Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 11/109 (10%) Query: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1200 LRC + +ARDLA D++ SDP+ V + ++++T +VK + P W++T +E E+ E Sbjct: 63 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET---FEFEL-QE 118 Query: 1201 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRL--AWFPL 1247 A A + VE +D D ++F+G+ + R+ + WF L Sbjct: 119 GAMEA-----LCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRL 162 Score = 48.9 bits (115), Expect = 5e-05 Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 3/91 (3%) Query: 2 LCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 61 L C ++ A +L ++ SDP + ++G + T ++K S P WNE FE++L+ ++ Sbjct: 63 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAME 122 Query: 62 QGSELHVVVKDHETMGRNRFLGEAKVPLREV 92 L V D + + RN FLG+ + ++ + Sbjct: 123 ---ALCVEAWDWDLVSRNDFLGKVVIDVQRL 150 Score = 48.5 bits (114), Expect = 7e-05 Identities = 24/94 (25%), Positives = 52/94 (55%), Gaps = 2/94 (2%) Query: 1582 GPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFEL 1641 G + C +R ++ A L PKD NG DP++++ K + + + + + P + + FE Sbjct: 57 GARACRLRCSVLEARDLAPKDRNGTSDPFVRVRY--KGRTRETSIVKKSCYPRWNETFEF 114 Query: 1642 TCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLE 1675 + L + +D+DL+S+++ +G+ V+D++ Sbjct: 115 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQ 148 Score = 42.4 bits (98), Expect = 0.005 Identities = 31/136 (22%), Positives = 53/136 (38%), Gaps = 18/136 (13%) Query: 351 APLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFE 410 A L DP E+ + E +L R V A DL D Sbjct: 33 AHLTEVDPDEEVQG-EIHLRLEVWPGARACRLRCSVLEARDLAPKD-------------- 77 Query: 411 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRL 470 + DPFV V + G+ + I++K+ P+WN+ +M E + + DWD + Sbjct: 78 --RNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAM-EALCVEAWDWDLV 134 Query: 471 THNDIVATTYLSMSKI 486 + ND + + + ++ Sbjct: 135 SRNDFLGKVVIDVQRL 150 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.138 0.428 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,715,309 Number of Sequences: 37866 Number of extensions: 4652610 Number of successful extensions: 16734 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 74 Number of HSP's successfully gapped in prelim test: 218 Number of HSP's that attempted gapping in prelim test: 14412 Number of HSP's gapped (non-prelim): 1763 length of query: 2088 length of database: 18,247,518 effective HSP length: 118 effective length of query: 1970 effective length of database: 13,779,330 effective search space: 27145280100 effective search space used: 27145280100 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.