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Search of human proteins with 195976762
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|195976762 dysferlin isoform 13 [Homo sapiens]
(2097 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|195976762 dysferlin isoform 13 [Homo sapiens] 4323 0.0
gi|195976760 dysferlin isoform 12 [Homo sapiens] 4312 0.0
gi|195976764 dysferlin isoform 14 [Homo sapiens] 4311 0.0
gi|195976775 dysferlin isoform 4 [Homo sapiens] 4273 0.0
gi|195976766 dysferlin isoform 7 [Homo sapiens] 4262 0.0
gi|195976779 dysferlin isoform 1 [Homo sapiens] 4260 0.0
gi|195976754 dysferlin isoform 9 [Homo sapiens] 4241 0.0
gi|4503431 dysferlin isoform 8 [Homo sapiens] 4231 0.0
gi|195976756 dysferlin isoform 10 [Homo sapiens] 4229 0.0
gi|195976758 dysferlin isoform 11 [Homo sapiens] 4218 0.0
gi|195976777 dysferlin isoform 3 [Homo sapiens] 4191 0.0
gi|195976821 dysferlin isoform 2 [Homo sapiens] 4180 0.0
gi|195976773 dysferlin isoform 5 [Homo sapiens] 4179 0.0
gi|195976769 dysferlin isoform 6 [Homo sapiens] 4168 0.0
gi|19718759 myoferlin isoform b [Homo sapiens] 2374 0.0
gi|7305053 myoferlin isoform a [Homo sapiens] 2367 0.0
gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens] 1400 0.0
gi|35493868 otoferlin isoform b [Homo sapiens] 720 0.0
gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens] 714 0.0
gi|35493853 otoferlin isoform c [Homo sapiens] 712 0.0
gi|35493860 otoferlin isoform d [Homo sapiens] 712 0.0
gi|34740331 otoferlin isoform a [Homo sapiens] 712 0.0
gi|119120884 fer-1-like 6 [Homo sapiens] 709 0.0
gi|4759026 RAS protein activator like 1 [Homo sapiens] 65 5e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 54 1e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 54 1e-06
gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo... 54 2e-06
gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom... 54 2e-06
gi|239743309 PREDICTED: similar to calcium-promoted Ras inactiva... 53 3e-06
gi|239743307 PREDICTED: similar to calcium-promoted Ras inactiva... 53 3e-06
>gi|195976762 dysferlin isoform 13 [Homo sapiens]
Length = 2097
Score = 4323 bits (11212), Expect = 0.0
Identities = 2097/2097 (100%), Positives = 2097/2097 (100%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180
Query: 181 APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240
APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS
Sbjct: 181 APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240
Query: 241 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300
RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN
Sbjct: 241 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300
Query: 301 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360
LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF
Sbjct: 301 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360
Query: 361 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420
SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE
Sbjct: 361 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420
Query: 421 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480
DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP
Sbjct: 421 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480
Query: 481 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI 540
AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI
Sbjct: 481 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI 540
Query: 541 NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV 600
NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV
Sbjct: 541 NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV 600
Query: 601 EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD 660
EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD
Sbjct: 601 EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD 660
Query: 661 GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE 720
GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE
Sbjct: 661 GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE 720
Query: 721 DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS 780
DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS
Sbjct: 721 DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS 780
Query: 781 ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY 840
ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY
Sbjct: 781 ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY 840
Query: 841 CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE 900
CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE
Sbjct: 841 CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE 900
Query: 901 NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD 960
NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD
Sbjct: 901 NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD 960
Query: 961 AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL 1020
AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL
Sbjct: 961 AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL 1020
Query: 1021 NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE 1080
NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE
Sbjct: 1021 NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE 1080
Query: 1081 AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK 1140
AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK
Sbjct: 1081 AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK 1140
Query: 1141 SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH 1200
SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH
Sbjct: 1141 SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH 1200
Query: 1201 QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1260
QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC
Sbjct: 1201 QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1260
Query: 1261 ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1320
ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE
Sbjct: 1261 ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1320
Query: 1321 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1380
DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG
Sbjct: 1321 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1380
Query: 1381 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1440
QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR
Sbjct: 1381 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1440
Query: 1441 SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFA 1500
SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFA
Sbjct: 1441 SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFA 1500
Query: 1501 SIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIG 1560
SIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIG
Sbjct: 1501 SIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIG 1560
Query: 1561 EFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYI 1620
EFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYI
Sbjct: 1561 EFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYI 1620
Query: 1621 KISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETV 1680
KISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETV
Sbjct: 1621 KISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETV 1680
Query: 1681 VDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMF 1740
VDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMF
Sbjct: 1681 VDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMF 1740
Query: 1741 QDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKL 1800
QDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKL
Sbjct: 1741 QDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKL 1800
Query: 1801 QMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGW 1860
QMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGW
Sbjct: 1801 QMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGW 1860
Query: 1861 MIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIP 1920
MIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIP
Sbjct: 1861 MIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIP 1920
Query: 1921 ARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQK 1980
ARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQK
Sbjct: 1921 ARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQK 1980
Query: 1981 TVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDT 2040
TVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDT
Sbjct: 1981 TVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDT 2040
Query: 2041 SFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2097
SFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2041 SFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2097
>gi|195976760 dysferlin isoform 12 [Homo sapiens]
Length = 2111
Score = 4312 bits (11184), Expect = 0.0
Identities = 2096/2111 (99%), Positives = 2097/2111 (99%), Gaps = 14/2111 (0%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180
Query: 181 APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240
APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS
Sbjct: 181 APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240
Query: 241 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300
RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN
Sbjct: 241 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300
Query: 301 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360
LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF
Sbjct: 301 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360
Query: 361 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420
SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE
Sbjct: 361 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420
Query: 421 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480
DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP
Sbjct: 421 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480
Query: 481 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------VD 526
AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +D
Sbjct: 481 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLD 540
Query: 527 DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 586
DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE
Sbjct: 541 DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 600
Query: 587 QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 646
QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL
Sbjct: 601 QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 660
Query: 647 PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 706
PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL
Sbjct: 661 PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 720
Query: 707 EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 766
EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS
Sbjct: 721 EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 780
Query: 767 QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 826
QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV
Sbjct: 781 QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 840
Query: 827 PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 886
PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ
Sbjct: 841 PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 900
Query: 887 FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 946
FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD
Sbjct: 901 FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 960
Query: 947 WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 1006
WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP
Sbjct: 961 WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 1020
Query: 1007 LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1066
LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD
Sbjct: 1021 LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1080
Query: 1067 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1126
LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV
Sbjct: 1081 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1140
Query: 1127 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1186
FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK
Sbjct: 1141 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1200
Query: 1187 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1246
DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY
Sbjct: 1201 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1260
Query: 1247 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1306
DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG
Sbjct: 1261 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1320
Query: 1307 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1366
FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL
Sbjct: 1321 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1380
Query: 1367 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1426
ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR
Sbjct: 1381 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1440
Query: 1427 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1486
QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI
Sbjct: 1441 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1500
Query: 1487 QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYR 1546
QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYR
Sbjct: 1501 QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYR 1560
Query: 1547 GKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFG 1606
GKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFG
Sbjct: 1561 GKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFG 1620
Query: 1607 LQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYD 1666
LQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYD
Sbjct: 1621 LQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYD 1680
Query: 1667 YDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQH 1726
YDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQH
Sbjct: 1681 YDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQH 1740
Query: 1727 RVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRP 1786
RVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRP
Sbjct: 1741 RVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRP 1800
Query: 1787 LYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLS 1846
LYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLS
Sbjct: 1801 LYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLS 1860
Query: 1847 LTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKK 1906
LTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKK
Sbjct: 1861 LTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKK 1920
Query: 1907 DAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD 1966
DAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD
Sbjct: 1921 DAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD 1980
Query: 1967 AFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEP 2026
AFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEP
Sbjct: 1981 AFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEP 2040
Query: 2027 NMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPN 2086
NMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPN
Sbjct: 2041 NMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPN 2100
Query: 2087 YAAMKLVKPFS 2097
YAAMKLVKPFS
Sbjct: 2101 YAAMKLVKPFS 2111
>gi|195976764 dysferlin isoform 14 [Homo sapiens]
Length = 2118
Score = 4311 bits (11180), Expect = 0.0
Identities = 2097/2118 (99%), Positives = 2097/2118 (99%), Gaps = 21/2118 (0%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180
Query: 181 APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240
APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS
Sbjct: 181 APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240
Query: 241 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300
RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN
Sbjct: 241 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300
Query: 301 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360
LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF
Sbjct: 301 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360
Query: 361 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420
SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE
Sbjct: 361 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420
Query: 421 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480
DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP
Sbjct: 421 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480
Query: 481 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI 540
AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI
Sbjct: 481 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI 540
Query: 541 NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV 600
NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV
Sbjct: 541 NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV 600
Query: 601 EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD 660
EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD
Sbjct: 601 EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD 660
Query: 661 GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE 720
GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE
Sbjct: 661 GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE 720
Query: 721 DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS 780
DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS
Sbjct: 721 DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS 780
Query: 781 ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY 840
ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY
Sbjct: 781 ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY 840
Query: 841 CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE 900
CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE
Sbjct: 841 CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE 900
Query: 901 NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD 960
NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD
Sbjct: 901 NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD 960
Query: 961 AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL 1020
AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL
Sbjct: 961 AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL 1020
Query: 1021 NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE 1080
NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE
Sbjct: 1021 NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE 1080
Query: 1081 AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK 1140
AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK
Sbjct: 1081 AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK 1140
Query: 1141 SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH 1200
SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH
Sbjct: 1141 SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH 1200
Query: 1201 QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1260
QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC
Sbjct: 1201 QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1260
Query: 1261 ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1320
ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE
Sbjct: 1261 ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1320
Query: 1321 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1380
DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG
Sbjct: 1321 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1380
Query: 1381 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1440
QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR
Sbjct: 1381 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1440
Query: 1441 SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ------------- 1487
SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ
Sbjct: 1441 SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNT 1500
Query: 1488 --------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFC 1539
EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFC
Sbjct: 1501 ASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFC 1560
Query: 1540 NTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRI 1599
NTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRI
Sbjct: 1561 NTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRI 1620
Query: 1600 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1659
YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD
Sbjct: 1621 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1680
Query: 1660 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1719
LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL
Sbjct: 1681 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1740
Query: 1720 HLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVP 1779
HLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVP
Sbjct: 1741 HLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVP 1800
Query: 1780 EHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRD 1839
EHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRD
Sbjct: 1801 EHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRD 1860
Query: 1840 VILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQ 1899
VILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQ
Sbjct: 1861 VILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQ 1920
Query: 1900 VCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKC 1959
VCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKC
Sbjct: 1921 VCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKC 1980
Query: 1960 SLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPA 2019
SLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPA
Sbjct: 1981 SLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPA 2040
Query: 2020 GQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAI 2079
GQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAI
Sbjct: 2041 GQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAI 2100
Query: 2080 FIYAFPNYAAMKLVKPFS 2097
FIYAFPNYAAMKLVKPFS
Sbjct: 2101 FIYAFPNYAAMKLVKPFS 2118
>gi|195976775 dysferlin isoform 4 [Homo sapiens]
Length = 2098
Score = 4273 bits (11081), Expect = 0.0
Identities = 2077/2098 (98%), Positives = 2081/2098 (99%), Gaps = 1/2098 (0%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
Query: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
Query: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
Query: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
Query: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
Query: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
Query: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 539
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540
Query: 540 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 599
INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600
Query: 600 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 659
VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660
Query: 660 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 719
DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720
Query: 720 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 779
EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780
Query: 780 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 839
SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840
Query: 840 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 899
YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900
Query: 900 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 959
ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960
Query: 960 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1019
DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020
Query: 1020 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1079
LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080
Query: 1080 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1139
EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140
Query: 1140 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1199
KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200
Query: 1200 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1259
HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260
Query: 1260 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1319
CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320
Query: 1320 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1379
EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380
Query: 1380 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1439
GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440
Query: 1440 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF 1499
RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF
Sbjct: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF 1500
Query: 1500 ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI 1559
ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI
Sbjct: 1501 ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI 1560
Query: 1560 GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY 1619
GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY
Sbjct: 1561 GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY 1620
Query: 1620 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1679
IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET
Sbjct: 1621 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1680
Query: 1680 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM 1739
VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM
Sbjct: 1681 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM 1740
Query: 1740 FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK 1799
FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK
Sbjct: 1741 FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK 1800
Query: 1800 LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG 1859
LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG
Sbjct: 1801 LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG 1860
Query: 1860 WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI 1919
WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI
Sbjct: 1861 WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI 1920
Query: 1920 PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ 1979
PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ
Sbjct: 1921 PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ 1980
Query: 1980 KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD 2039
KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD
Sbjct: 1981 KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD 2040
Query: 2040 TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2097
TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2041 TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2098
>gi|195976766 dysferlin isoform 7 [Homo sapiens]
Length = 2112
Score = 4262 bits (11053), Expect = 0.0
Identities = 2076/2112 (98%), Positives = 2081/2112 (98%), Gaps = 15/2112 (0%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
Query: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
Query: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
Query: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
Query: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
Query: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
Query: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 525
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
Query: 526 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 585
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 541 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
Query: 586 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 645
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 601 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
Query: 646 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 705
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 661 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
Query: 706 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 765
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 721 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
Query: 766 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 825
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 781 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
Query: 826 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 885
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 841 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
Query: 886 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 945
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 901 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
Query: 946 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1005
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 961 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
Query: 1006 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1065
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
Query: 1066 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1125
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
Query: 1126 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1185
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
Query: 1186 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1245
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
Query: 1246 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1305
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
Query: 1306 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1365
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
Query: 1366 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1425
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
Query: 1426 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1485
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
Query: 1486 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1545
IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1501 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1560
Query: 1546 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1605
RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1561 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1620
Query: 1606 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1665
GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1621 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1680
Query: 1666 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1725
DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1681 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1740
Query: 1726 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1785
HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1741 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1800
Query: 1786 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1845
PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1801 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1860
Query: 1846 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1905
SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1861 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1920
Query: 1906 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1965
KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1921 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1980
Query: 1966 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2025
DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1981 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2040
Query: 2026 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2085
PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2041 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2100
Query: 2086 NYAAMKLVKPFS 2097
NYAAMKLVKPFS
Sbjct: 2101 NYAAMKLVKPFS 2112
>gi|195976779 dysferlin isoform 1 [Homo sapiens]
Length = 2119
Score = 4260 bits (11049), Expect = 0.0
Identities = 2077/2119 (98%), Positives = 2081/2119 (98%), Gaps = 22/2119 (1%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
Query: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
Query: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
Query: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
Query: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
Query: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
Query: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 539
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540
Query: 540 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 599
INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 541 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600
Query: 600 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 659
VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 601 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660
Query: 660 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 719
DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 661 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720
Query: 720 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 779
EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 721 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780
Query: 780 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 839
SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 781 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840
Query: 840 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 899
YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 841 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900
Query: 900 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 959
ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 901 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960
Query: 960 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1019
DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 961 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020
Query: 1020 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1079
LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080
Query: 1080 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1139
EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140
Query: 1140 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1199
KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200
Query: 1200 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1259
HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260
Query: 1260 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1319
CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320
Query: 1320 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1379
EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380
Query: 1380 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1439
GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440
Query: 1440 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ------------ 1487
RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ
Sbjct: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1500
Query: 1488 ---------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1538
EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF
Sbjct: 1501 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1560
Query: 1539 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1598
CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR
Sbjct: 1561 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1620
Query: 1599 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1658
IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK
Sbjct: 1621 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1680
Query: 1659 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1718
DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL
Sbjct: 1681 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1740
Query: 1719 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1778
LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV
Sbjct: 1741 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1800
Query: 1779 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1838
PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR
Sbjct: 1801 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1860
Query: 1839 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1898
DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE
Sbjct: 1861 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1920
Query: 1899 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1958
QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK
Sbjct: 1921 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1980
Query: 1959 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2018
CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP
Sbjct: 1981 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2040
Query: 2019 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2078
AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA
Sbjct: 2041 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2100
Query: 2079 IFIYAFPNYAAMKLVKPFS 2097
IFIYAFPNYAAMKLVKPFS
Sbjct: 2101 IFIYAFPNYAAMKLVKPFS 2119
>gi|195976754 dysferlin isoform 9 [Homo sapiens]
Length = 2066
Score = 4241 bits (11000), Expect = 0.0
Identities = 2066/2097 (98%), Positives = 2066/2097 (98%), Gaps = 31/2097 (1%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA---------------------------- 152
Query: 181 APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS
Sbjct: 153 ---DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 209
Query: 241 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300
RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN
Sbjct: 210 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 269
Query: 301 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360
LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF
Sbjct: 270 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 329
Query: 361 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420
SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE
Sbjct: 330 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 389
Query: 421 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480
DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP
Sbjct: 390 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 449
Query: 481 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI 540
AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI
Sbjct: 450 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI 509
Query: 541 NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV 600
NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV
Sbjct: 510 NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV 569
Query: 601 EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD 660
EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD
Sbjct: 570 EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD 629
Query: 661 GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE 720
GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE
Sbjct: 630 GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE 689
Query: 721 DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS 780
DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS
Sbjct: 690 DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS 749
Query: 781 ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY 840
ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY
Sbjct: 750 ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY 809
Query: 841 CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE 900
CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE
Sbjct: 810 CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE 869
Query: 901 NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD 960
NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD
Sbjct: 870 NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD 929
Query: 961 AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL 1020
AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL
Sbjct: 930 AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL 989
Query: 1021 NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE 1080
NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE
Sbjct: 990 NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE 1049
Query: 1081 AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK 1140
AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK
Sbjct: 1050 AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK 1109
Query: 1141 SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH 1200
SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH
Sbjct: 1110 SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH 1169
Query: 1201 QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1260
QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC
Sbjct: 1170 QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1229
Query: 1261 ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1320
ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE
Sbjct: 1230 ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1289
Query: 1321 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1380
DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG
Sbjct: 1290 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1349
Query: 1381 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1440
QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR
Sbjct: 1350 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1409
Query: 1441 SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFA 1500
SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFA
Sbjct: 1410 SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFA 1469
Query: 1501 SIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIG 1560
SIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIG
Sbjct: 1470 SIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIG 1529
Query: 1561 EFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYI 1620
EFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYI
Sbjct: 1530 EFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYI 1589
Query: 1621 KISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETV 1680
KISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETV
Sbjct: 1590 KISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETV 1649
Query: 1681 VDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMF 1740
VDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMF
Sbjct: 1650 VDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMF 1709
Query: 1741 QDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKL 1800
QDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKL
Sbjct: 1710 QDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKL 1769
Query: 1801 QMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGW 1860
QMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGW
Sbjct: 1770 QMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGW 1829
Query: 1861 MIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIP 1920
MIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIP
Sbjct: 1830 MIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIP 1889
Query: 1921 ARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQK 1980
ARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQK
Sbjct: 1890 ARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQK 1949
Query: 1981 TVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDT 2040
TVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDT
Sbjct: 1950 TVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDT 2009
Query: 2041 SFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2097
SFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2010 SFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2066
>gi|4503431 dysferlin isoform 8 [Homo sapiens]
Length = 2080
Score = 4231 bits (10972), Expect = 0.0
Identities = 2065/2111 (97%), Positives = 2066/2111 (97%), Gaps = 45/2111 (2%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA---------------------------- 152
Query: 181 APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS
Sbjct: 153 ---DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 209
Query: 241 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300
RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN
Sbjct: 210 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 269
Query: 301 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360
LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF
Sbjct: 270 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 329
Query: 361 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420
SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE
Sbjct: 330 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 389
Query: 421 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480
DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP
Sbjct: 390 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 449
Query: 481 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------VD 526
AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +D
Sbjct: 450 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLD 509
Query: 527 DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 586
DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE
Sbjct: 510 DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 569
Query: 587 QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 646
QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL
Sbjct: 570 QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 629
Query: 647 PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 706
PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL
Sbjct: 630 PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 689
Query: 707 EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 766
EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS
Sbjct: 690 EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 749
Query: 767 QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 826
QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV
Sbjct: 750 QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 809
Query: 827 PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 886
PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ
Sbjct: 810 PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 869
Query: 887 FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 946
FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD
Sbjct: 870 FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 929
Query: 947 WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 1006
WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP
Sbjct: 930 WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 989
Query: 1007 LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1066
LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD
Sbjct: 990 LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1049
Query: 1067 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1126
LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV
Sbjct: 1050 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1109
Query: 1127 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1186
FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK
Sbjct: 1110 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1169
Query: 1187 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1246
DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY
Sbjct: 1170 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1229
Query: 1247 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1306
DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG
Sbjct: 1230 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1289
Query: 1307 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1366
FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL
Sbjct: 1290 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1349
Query: 1367 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1426
ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR
Sbjct: 1350 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1409
Query: 1427 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1486
QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI
Sbjct: 1410 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1469
Query: 1487 QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYR 1546
QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYR
Sbjct: 1470 QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYR 1529
Query: 1547 GKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFG 1606
GKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFG
Sbjct: 1530 GKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFG 1589
Query: 1607 LQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYD 1666
LQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYD
Sbjct: 1590 LQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYD 1649
Query: 1667 YDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQH 1726
YDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQH
Sbjct: 1650 YDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQH 1709
Query: 1727 RVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRP 1786
RVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRP
Sbjct: 1710 RVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRP 1769
Query: 1787 LYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLS 1846
LYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLS
Sbjct: 1770 LYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLS 1829
Query: 1847 LTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKK 1906
LTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKK
Sbjct: 1830 LTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKK 1889
Query: 1907 DAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD 1966
DAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD
Sbjct: 1890 DAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD 1949
Query: 1967 AFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEP 2026
AFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEP
Sbjct: 1950 AFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEP 2009
Query: 2027 NMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPN 2086
NMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPN
Sbjct: 2010 NMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPN 2069
Query: 2087 YAAMKLVKPFS 2097
YAAMKLVKPFS
Sbjct: 2070 YAAMKLVKPFS 2080
>gi|195976756 dysferlin isoform 10 [Homo sapiens]
Length = 2087
Score = 4229 bits (10968), Expect = 0.0
Identities = 2066/2118 (97%), Positives = 2066/2118 (97%), Gaps = 52/2118 (2%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA---------------------------- 152
Query: 181 APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS
Sbjct: 153 ---DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 209
Query: 241 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300
RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN
Sbjct: 210 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 269
Query: 301 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360
LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF
Sbjct: 270 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 329
Query: 361 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420
SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE
Sbjct: 330 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 389
Query: 421 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480
DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP
Sbjct: 390 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 449
Query: 481 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI 540
AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI
Sbjct: 450 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI 509
Query: 541 NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV 600
NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV
Sbjct: 510 NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV 569
Query: 601 EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD 660
EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD
Sbjct: 570 EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD 629
Query: 661 GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE 720
GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE
Sbjct: 630 GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE 689
Query: 721 DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS 780
DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS
Sbjct: 690 DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS 749
Query: 781 ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY 840
ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY
Sbjct: 750 ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY 809
Query: 841 CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE 900
CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE
Sbjct: 810 CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE 869
Query: 901 NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD 960
NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD
Sbjct: 870 NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD 929
Query: 961 AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL 1020
AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL
Sbjct: 930 AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL 989
Query: 1021 NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE 1080
NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE
Sbjct: 990 NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE 1049
Query: 1081 AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK 1140
AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK
Sbjct: 1050 AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK 1109
Query: 1141 SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH 1200
SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH
Sbjct: 1110 SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH 1169
Query: 1201 QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1260
QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC
Sbjct: 1170 QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1229
Query: 1261 ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1320
ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE
Sbjct: 1230 ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1289
Query: 1321 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1380
DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG
Sbjct: 1290 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1349
Query: 1381 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1440
QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR
Sbjct: 1350 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1409
Query: 1441 SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ------------- 1487
SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ
Sbjct: 1410 SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNT 1469
Query: 1488 --------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFC 1539
EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFC
Sbjct: 1470 ASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFC 1529
Query: 1540 NTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRI 1599
NTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRI
Sbjct: 1530 NTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRI 1589
Query: 1600 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1659
YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD
Sbjct: 1590 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1649
Query: 1660 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1719
LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL
Sbjct: 1650 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1709
Query: 1720 HLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVP 1779
HLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVP
Sbjct: 1710 HLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVP 1769
Query: 1780 EHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRD 1839
EHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRD
Sbjct: 1770 EHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRD 1829
Query: 1840 VILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQ 1899
VILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQ
Sbjct: 1830 VILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQ 1889
Query: 1900 VCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKC 1959
VCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKC
Sbjct: 1890 VCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKC 1949
Query: 1960 SLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPA 2019
SLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPA
Sbjct: 1950 SLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPA 2009
Query: 2020 GQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAI 2079
GQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAI
Sbjct: 2010 GQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAI 2069
Query: 2080 FIYAFPNYAAMKLVKPFS 2097
FIYAFPNYAAMKLVKPFS
Sbjct: 2070 FIYAFPNYAAMKLVKPFS 2087
>gi|195976758 dysferlin isoform 11 [Homo sapiens]
Length = 2101
Score = 4218 bits (10940), Expect = 0.0
Identities = 2065/2132 (96%), Positives = 2066/2132 (96%), Gaps = 66/2132 (3%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA---------------------------- 152
Query: 181 APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS
Sbjct: 153 ---DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 209
Query: 241 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300
RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN
Sbjct: 210 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 269
Query: 301 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360
LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF
Sbjct: 270 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 329
Query: 361 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420
SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE
Sbjct: 330 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 389
Query: 421 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480
DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP
Sbjct: 390 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 449
Query: 481 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------VD 526
AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +D
Sbjct: 450 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLD 509
Query: 527 DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 586
DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE
Sbjct: 510 DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 569
Query: 587 QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 646
QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL
Sbjct: 570 QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 629
Query: 647 PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 706
PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL
Sbjct: 630 PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 689
Query: 707 EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 766
EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS
Sbjct: 690 EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 749
Query: 767 QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 826
QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV
Sbjct: 750 QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 809
Query: 827 PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 886
PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ
Sbjct: 810 PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 869
Query: 887 FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 946
FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD
Sbjct: 870 FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 929
Query: 947 WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 1006
WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP
Sbjct: 930 WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 989
Query: 1007 LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1066
LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD
Sbjct: 990 LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1049
Query: 1067 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1126
LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV
Sbjct: 1050 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1109
Query: 1127 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1186
FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK
Sbjct: 1110 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1169
Query: 1187 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1246
DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY
Sbjct: 1170 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1229
Query: 1247 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1306
DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG
Sbjct: 1230 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1289
Query: 1307 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1366
FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL
Sbjct: 1290 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1349
Query: 1367 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1426
ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR
Sbjct: 1350 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1409
Query: 1427 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1486
QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI
Sbjct: 1410 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1469
Query: 1487 Q---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQ 1525
Q EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQ
Sbjct: 1470 QLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQ 1529
Query: 1526 LENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFH 1585
LENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFH
Sbjct: 1530 LENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFH 1589
Query: 1586 QLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFG 1645
QLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFG
Sbjct: 1590 QLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFG 1649
Query: 1646 KMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSG 1705
KMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSG
Sbjct: 1650 KMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSG 1709
Query: 1706 PNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEE 1765
PNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEE
Sbjct: 1710 PNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEE 1769
Query: 1766 RLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRA 1825
RLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRA
Sbjct: 1770 RLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRA 1829
Query: 1826 RRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFN 1885
RRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFN
Sbjct: 1830 RRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFN 1889
Query: 1886 WRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLD 1945
WRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLD
Sbjct: 1890 WRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLD 1949
Query: 1946 LNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMT 2005
LNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMT
Sbjct: 1950 LNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMT 2009
Query: 2006 LEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAII 2065
LEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAII
Sbjct: 2010 LEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAII 2069
Query: 2066 LFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2097
LFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2070 LFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2101
>gi|195976777 dysferlin isoform 3 [Homo sapiens]
Length = 2067
Score = 4191 bits (10869), Expect = 0.0
Identities = 2046/2098 (97%), Positives = 2050/2098 (97%), Gaps = 32/2098 (1%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
Query: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
Query: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
Query: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
Query: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
Query: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
Query: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 539
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 509
Query: 540 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 599
INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 510 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 569
Query: 600 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 659
VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 570 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 629
Query: 660 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 719
DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 630 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 689
Query: 720 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 779
EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 690 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 749
Query: 780 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 839
SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 750 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 809
Query: 840 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 899
YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 810 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 869
Query: 900 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 959
ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 870 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 929
Query: 960 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1019
DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 930 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 989
Query: 1020 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1079
LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 990 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1049
Query: 1080 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1139
EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1050 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1109
Query: 1140 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1199
KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1110 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1169
Query: 1200 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1259
HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1170 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1229
Query: 1260 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1319
CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1230 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1289
Query: 1320 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1379
EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1290 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1349
Query: 1380 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1439
GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1350 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1409
Query: 1440 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF 1499
RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF
Sbjct: 1410 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFF 1469
Query: 1500 ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI 1559
ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI
Sbjct: 1470 ASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVI 1529
Query: 1560 GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY 1619
GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY
Sbjct: 1530 GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPY 1589
Query: 1620 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1679
IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET
Sbjct: 1590 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1649
Query: 1680 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM 1739
VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM
Sbjct: 1650 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVM 1709
Query: 1740 FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK 1799
FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK
Sbjct: 1710 FQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGK 1769
Query: 1800 LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG 1859
LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG
Sbjct: 1770 LQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKG 1829
Query: 1860 WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI 1919
WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI
Sbjct: 1830 WMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKI 1889
Query: 1920 PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ 1979
PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ
Sbjct: 1890 PARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQ 1949
Query: 1980 KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD 2039
KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD
Sbjct: 1950 KTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPD 2009
Query: 2040 TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2097
TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2010 TSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2067
>gi|195976821 dysferlin isoform 2 [Homo sapiens]
Length = 2081
Score = 4180 bits (10841), Expect = 0.0
Identities = 2045/2112 (96%), Positives = 2050/2112 (97%), Gaps = 46/2112 (2%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
Query: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
Query: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
Query: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
Query: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
Query: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
Query: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 525
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 509
Query: 526 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 585
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 510 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 569
Query: 586 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 645
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 570 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 629
Query: 646 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 705
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 630 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 689
Query: 706 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 765
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 690 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 749
Query: 766 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 825
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 750 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 809
Query: 826 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 885
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 810 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 869
Query: 886 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 945
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 870 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 929
Query: 946 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1005
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 930 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 989
Query: 1006 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1065
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 990 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1049
Query: 1066 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1125
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1050 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1109
Query: 1126 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1185
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1110 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1169
Query: 1186 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1245
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1170 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1229
Query: 1246 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1305
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1230 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1289
Query: 1306 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1365
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1290 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1349
Query: 1366 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1425
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1350 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1409
Query: 1426 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1485
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1410 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1469
Query: 1486 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1545
IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1470 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1529
Query: 1546 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1605
RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1530 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1589
Query: 1606 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1665
GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1590 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1649
Query: 1666 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1725
DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1650 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1709
Query: 1726 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1785
HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1710 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1769
Query: 1786 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1845
PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1770 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1829
Query: 1846 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1905
SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1830 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1889
Query: 1906 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1965
KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1890 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1949
Query: 1966 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2025
DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1950 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2009
Query: 2026 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2085
PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2010 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2069
Query: 2086 NYAAMKLVKPFS 2097
NYAAMKLVKPFS
Sbjct: 2070 NYAAMKLVKPFS 2081
>gi|195976773 dysferlin isoform 5 [Homo sapiens]
Length = 2088
Score = 4179 bits (10837), Expect = 0.0
Identities = 2046/2119 (96%), Positives = 2050/2119 (96%), Gaps = 53/2119 (2%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
Query: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
Query: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
Query: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
Query: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
Query: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
Query: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 539
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 509
Query: 540 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 599
INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 510 INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 569
Query: 600 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 659
VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 570 VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 629
Query: 660 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 719
DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 630 DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 689
Query: 720 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 779
EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 690 EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 749
Query: 780 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 839
SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 750 SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 809
Query: 840 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 899
YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 810 YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 869
Query: 900 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 959
ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 870 ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 929
Query: 960 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1019
DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 930 DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 989
Query: 1020 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1079
LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 990 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1049
Query: 1080 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1139
EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1050 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1109
Query: 1140 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1199
KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1110 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1169
Query: 1200 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1259
HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1170 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1229
Query: 1260 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1319
CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1230 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1289
Query: 1320 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1379
EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1290 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1349
Query: 1380 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1439
GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1350 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1409
Query: 1440 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ------------ 1487
RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ
Sbjct: 1410 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1469
Query: 1488 ---------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1538
EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF
Sbjct: 1470 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1529
Query: 1539 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1598
CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR
Sbjct: 1530 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1589
Query: 1599 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1658
IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK
Sbjct: 1590 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1649
Query: 1659 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1718
DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL
Sbjct: 1650 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1709
Query: 1719 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1778
LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV
Sbjct: 1710 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1769
Query: 1779 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1838
PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR
Sbjct: 1770 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1829
Query: 1839 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1898
DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE
Sbjct: 1830 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1889
Query: 1899 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1958
QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK
Sbjct: 1890 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1949
Query: 1959 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2018
CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP
Sbjct: 1950 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2009
Query: 2019 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2078
AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA
Sbjct: 2010 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2069
Query: 2079 IFIYAFPNYAAMKLVKPFS 2097
IFIYAFPNYAAMKLVKPFS
Sbjct: 2070 IFIYAFPNYAAMKLVKPFS 2088
>gi|195976769 dysferlin isoform 6 [Homo sapiens]
Length = 2102
Score = 4168 bits (10809), Expect = 0.0
Identities = 2045/2133 (95%), Positives = 2050/2133 (96%), Gaps = 67/2133 (3%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 153
Query: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 154 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 209
Query: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 210 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 269
Query: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 270 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 329
Query: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 330 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 389
Query: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 390 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 449
Query: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 525
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 450 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 509
Query: 526 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 585
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 510 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 569
Query: 586 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 645
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 570 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 629
Query: 646 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 705
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 630 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 689
Query: 706 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 765
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 690 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 749
Query: 766 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 825
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 750 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 809
Query: 826 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 885
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 810 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 869
Query: 886 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 945
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 870 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 929
Query: 946 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1005
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 930 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 989
Query: 1006 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1065
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 990 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1049
Query: 1066 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1125
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1050 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1109
Query: 1126 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1185
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1110 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1169
Query: 1186 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1245
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1170 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1229
Query: 1246 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1305
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1230 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1289
Query: 1306 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1365
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1290 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1349
Query: 1366 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1425
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1350 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1409
Query: 1426 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1485
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1410 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1469
Query: 1486 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1524
IQ EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1470 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1529
Query: 1525 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1584
QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1530 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1589
Query: 1585 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1644
HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1590 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1649
Query: 1645 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1704
GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1650 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1709
Query: 1705 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1764
GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1710 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1769
Query: 1765 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1824
ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1770 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1829
Query: 1825 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1884
ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1830 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1889
Query: 1885 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1944
NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1890 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1949
Query: 1945 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2004
DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1950 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2009
Query: 2005 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2064
TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2010 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2069
Query: 2065 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2097
ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2070 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2102
>gi|19718759 myoferlin isoform b [Homo sapiens]
Length = 2048
Score = 2374 bits (6153), Expect = 0.0
Identities = 1178/2126 (55%), Positives = 1513/2126 (71%), Gaps = 111/2126 (5%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRV + A N+ D S +F KK+TK + N +NPVWNE E+DL+GIPLD
Sbjct: 1 MLRVIVESASNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLVL 119
S L ++VKD ET+G+N+ +G A V L+++ S S + LL+ K Q TGA++ L
Sbjct: 61 FSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATIDL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
+ Y P P P P L P++P + GG +
Sbjct: 121 VIGYDP-----PSAPHPNDLS-GPSVPGM-----GGDGEEDE------------------ 151
Query: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
G+ED D + G + GP + +L +R
Sbjct: 152 -------GDEDRLDNAVRGPGPK-------GPVGTVSEAQLA----------RRLTKVKN 187
Query: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
SR++LS+KPQDFQIRV+VIEGRQL G NI+PVVKV GQT RTRI +GN+P F+E F+
Sbjct: 188 SRRMLSNKPQDFQIRVRVIEGRQLSGNNIRPVVKVHVCGQTHRTRIKRGNNPFFDELFFY 247
Query: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
N+ +P EL DE I I V +S SLR D L+GEF++DVG +Y EP HA +RKWLLL+DP+D
Sbjct: 248 NVNMTPSELMDEIISIRVYNSHSLRADCLMGEFKIDVGFVYDEPGHAVMRKWLLLNDPED 307
Query: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
S+G++GY+K S+ VLG GDE P ER+D D +D+ESNLL P G+ALR F LK++RA
Sbjct: 308 TSSGSKGYMKVSMFVLGTGDEPPPERRDRDNDSDDVESNLLLPAGIALRWVTFLLKIYRA 367
Query: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
ED+PQMDDA VK+IFG ++KKNLVDPFVEVSFAGK +C+ I+EK ANP+WNQ + L
Sbjct: 368 EDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPEWNQVVNL 427
Query: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEV---DDYLGFLPTFG 536
FPS+CEK+++ I DWDRLT ND+V TTYL +SKI+A GGE+EV + +GF+PTFG
Sbjct: 428 QIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASGGEVEVNTGETEVGFVPTFG 487
Query: 537 PCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVE-HSEQKVEDLPAD 595
PCY+NLYGSPRE+TGFPDPY ELNTGKGEGVAYRGR+L+ L T L + ++K+E + D
Sbjct: 488 PCYLNLYGSPREYTGFPDPYDELNTGKGEGVAYRGRILVELATFLEKTPPDKKLEPISND 547
Query: 596 DILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYS 655
D+L VEKY RRRKYSL A F+SATMLQDV +AIQFEVSIGNYGNKFD TC PLASTTQYS
Sbjct: 548 DLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNKFDTTCKPLASTTQYS 607
Query: 656 RAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKA 715
RAVFDG +YYYLPW + KPVV L+SYWEDISHR++ N LL +A+RL+ +E + ++
Sbjct: 608 RAVFDGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTLLAMAERLQTNIEALKSGIQG 667
Query: 716 QCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALAL 775
+ + L +L DE+I L + T LD + +LR+ LSQI EAA+ +
Sbjct: 668 KIPANQLAELWLKLIDEVIEDTRYTLPLTEGKANVTVLDTQIRKLRSRSLSQIHEAAVRM 727
Query: 776 KLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSR 835
+ +++ + L + EDWL +L L EEPQNS+PDI+IWM++G+KR+AY R+PAHQVL+S
Sbjct: 728 RSEATDVKSTLAEIEDWLDKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYST 787
Query: 836 RGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVF 895
G N GK CGK QTIFLKYP EK G ++PV++RV +W GLS EK+FN FAEG +VF
Sbjct: 788 SGENASGKYCGKTQTIFLKYPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVF 847
Query: 896 AETYENETKLALVGNWGTTGLT-YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKT 954
AE YEN+ + G WGT+GL KFSDVTGKIKL ++ F P GW W G+W V PE++
Sbjct: 848 AEMYENQA--LMFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGEWIVDPERS 905
Query: 955 LLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDE 1014
LL + DAGH F +EV++N++R PGG W D YTD NG+K ++ CP GW+WED+
Sbjct: 906 LLTEADAGHTEFTDEVYQNESRYPGGDWKPAEDTYTDANGDKAASPSELTCPPGWEWEDD 965
Query: 1015 EWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALK 1074
WS D+NRAVDE+GWEY ITIPP+ KPK WV AEKMY+THRRRR VR R++DL+Q +
Sbjct: 966 AWSYDINRAVDEKGWEYGITIPPDHKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASST 1025
Query: 1075 RHRQAEAEG-EGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGAL 1133
E + EGWEYASL GWKFH + R +D FRRRRWRR+M P E G AA+F LEGAL
Sbjct: 1026 ARAMEELQDQEGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGAL 1085
Query: 1134 GGVM----DDKS-EDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1188
G D+KS E +T FG N P +SC FD YHLRCY+YQAR+L A+DKDS
Sbjct: 1086 GADTTEDGDEKSLEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCYVYQARNLLALDKDS 1145
Query: 1189 FSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDH 1248
FSDPYA + FLH+S+ T ++ +TLNPTWDQT+IF E+EI+GEP TV + PP +++EL+D+
Sbjct: 1146 FSDPYAHICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPKVIMELFDN 1205
Query: 1249 DTYGADEFMGRCICQP------SLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIH 1302
D G DEF+GR I P ++ P+L W P+ G + G++L + ELI R K
Sbjct: 1206 DQVGKDEFLGRSIFSPVVKLNSEMDITPKLLWHPVMNGDKACGDVLVTAELILRGK---- 1261
Query: 1303 HIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMK 1362
+ ++LP PPQR N+YMVPQ I+P +Q TAIEILAWGLRNMK
Sbjct: 1262 -----------------DGSNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMK 1304
Query: 1363 SYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKV 1422
++Q+A+I+SPSLVVECGG+ V+S VI+NL+K PNF LFM+V LP+EELY PP+ +KV
Sbjct: 1305 NFQMASITSPSLVVECGGERVESVVIKNLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKV 1364
Query: 1423 IDNRQFGRRPVVGQCTIRSLESFLCDPYSA-ESPSPQGGPDDVSLLS--PGEDVLIDIDD 1479
ID+RQFGR+PVVGQCTI L+ F CDPY+ E PQ SLLS P D++I+++D
Sbjct: 1365 IDHRQFGRKPVVGQCTIERLDRFRCDPYAGKEDIVPQ---LKASLLSAPPCRDIVIEMED 1421
Query: 1480 KEPLIPI----QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGL 1535
+PL+ +EEE +DWWSKF+AS GE EKCG Y++K + LK+Y+ +LENV FEGL
Sbjct: 1422 TKPLLASKLTEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGL 1481
Query: 1536 SDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQEC 1595
+DF +TFKLYRGK+ +E EDPSV+GEFKG F+IYPLP+DP++P PPRQF +L PQEC
Sbjct: 1482 TDFSDTFKLYRGKS-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQEC 1540
Query: 1596 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1655
VRIYIVR LQP+D NG CDPYIKI++GKK + D+D+YIP TL PVFG+M+EL+C LP
Sbjct: 1541 TVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLP 1600
Query: 1656 LEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRP 1715
EKDLKI++YDYD ++DEK+GET++DLENR LS+FG+ CG+P+ YCVSG N WRDQLRP
Sbjct: 1601 QEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRP 1660
Query: 1716 SQLLHLFCQQHRVKAPVYRTD--RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQ 1773
+QLL + P+ D R+ + ++YS++E EA +I + HLG EERLALH+L+
Sbjct: 1661 TQLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILR 1720
Query: 1774 QQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCI 1833
QGLVPEHVE+R L+S QP+I QGKLQMWVD+FPK+LG PGPPFNITPR+A++++LR I
Sbjct: 1721 TQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVI 1780
Query: 1834 IWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFD 1893
IWNT+DVILD+ S+TGE+MSDIYVKGW+ G EE+KQKTDVHYRSL GEGNFNWRF+FPFD
Sbjct: 1781 IWNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFD 1840
Query: 1894 YLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPA 1953
YLPAEQ+C +AKK+ FW +D+TE +IP R++ QIWDNDKFS DD+LG L+LDL PA
Sbjct: 1841 YLPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPA 1900
Query: 1954 KTAKKCSLDQLDD--AFHP--EWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 2009
K+ +KC LD + D A +P SLFEQK++KGWWPC AE+ +++AGK+EMTLEI+
Sbjct: 1901 KSPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEIL 1960
Query: 2010 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2069
E E +ERPAG+GRDEPNMNPKL+ P RP+TSFLWFT+P KTMKFI+WRRF+W II +
Sbjct: 1961 NEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLF 2020
Query: 2070 LFILLLFLAIFIYAFPNYAAMKLVKP 2095
L ILLLF+A+ +Y+ PNY +MK+VKP
Sbjct: 2021 LLILLLFVAVLLYSLPNYLSMKIVKP 2046
>gi|7305053 myoferlin isoform a [Homo sapiens]
Length = 2061
Score = 2367 bits (6133), Expect = 0.0
Identities = 1177/2139 (55%), Positives = 1512/2139 (70%), Gaps = 124/2139 (5%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRV + A N+ D S +F KK+TK + N +NPVWNE E+DL+GIPLD
Sbjct: 1 MLRVIVESASNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLVL 119
S L ++VKD ET+G+N+ +G A V L+++ S S + LL+ K Q TGA++ L
Sbjct: 61 FSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATIDL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 179
+ Y P P P P L P++P + GG +
Sbjct: 121 VIGYDP-----PSAPHPNDLS-GPSVPGM-----GGDGEEDE------------------ 151
Query: 180 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
G+ED D + G + GP + +L +R
Sbjct: 152 -------GDEDRLDNAVRGPGPK-------GPVGTVSEAQLA----------RRLTKVKN 187
Query: 240 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 299
SR++LS+KPQDFQIRV+VIEGRQL G NI+PVVKV GQT RTRI +GN+P F+E F+
Sbjct: 188 SRRMLSNKPQDFQIRVRVIEGRQLSGNNIRPVVKVHVCGQTHRTRIKRGNNPFFDELFFY 247
Query: 300 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 359
N+ +P EL DE I I V +S SLR D L+GEF++DVG +Y EP HA +RKWLLL+DP+D
Sbjct: 248 NVNMTPSELMDEIISIRVYNSHSLRADCLMGEFKIDVGFVYDEPGHAVMRKWLLLNDPED 307
Query: 360 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 419
S+G++GY+K S+ VLG GDE P ER+D D +D+ESNLL P G+ALR F LK++RA
Sbjct: 308 TSSGSKGYMKVSMFVLGTGDEPPPERRDRDNDSDDVESNLLLPAGIALRWVTFLLKIYRA 367
Query: 420 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 479
ED+PQMDDA VK+IFG ++KKNLVDPFVEVSFAGK +C+ I+EK ANP+WNQ + L
Sbjct: 368 EDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPEWNQVVNL 427
Query: 480 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------- 524
FPS+CEK+++ I DWDRLT ND+V TTYL +SKI+A GGE+E
Sbjct: 428 QIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASGGEVEDFSSSGTGAASYTVN 487
Query: 525 -VDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVE 583
+ +GF+PTFGPCY+NLYGSPRE+TGFPDPY ELNTGKGEGVAYRGR+L+ L T L +
Sbjct: 488 TGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNTGKGEGVAYRGRILVELATFLEK 547
Query: 584 -HSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFD 642
++K+E + DD+L VEKY RRRKYSL A F+SATMLQDV +AIQFEVSIGNYGNKFD
Sbjct: 548 TPPDKKLEPISNDDLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNKFD 607
Query: 643 MTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRL 702
TC PLASTTQYSRAVFDG +YYYLPW + KPVV L+SYWEDISHR++ N LL +A+RL
Sbjct: 608 TTCKPLASTTQYSRAVFDGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTLLAMAERL 667
Query: 703 EAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRT 762
+ +E + ++ + + L +L DE+I L + T LD + +LR+
Sbjct: 668 QTNIEALKSGIQGKIPANQLAELWLKLIDEVIEDTRYTLPLTEGKANVTVLDTQIRKLRS 727
Query: 763 HHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVA 822
LSQI EAA+ ++ +++ + L + EDWL +L L EEPQNS+PDI+IWM++G+KR+A
Sbjct: 728 RSLSQIHEAAVRMRSEATDVKSTLAEIEDWLDKLMQLTEEPQNSMPDIIIWMIRGEKRLA 787
Query: 823 YQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEK 882
Y R+PAHQVL+S G N GK CGK QTIFLKYP EK G ++PV++RV +W GLS EK
Sbjct: 788 YARIPAHQVLYSTSGENASGKYCGKTQTIFLKYPQEKNNGPKVPVELRVNIWLGLSAVEK 847
Query: 883 EFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT-YPKFSDVTGKIKLPKDSFRPSAGW 941
+FN FAEG +VFAE YEN+ + G WGT+GL KFSDVTGKIKL ++ F P GW
Sbjct: 848 KFNSFAEGTFTVFAEMYENQA--LMFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKGW 905
Query: 942 TWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKD 1001
W G+W V PE++LL + DAGH F +EV++N++R PGG W D YTD NG+K
Sbjct: 906 EWEGEWIVDPERSLLTEADAGHTEFTDEVYQNESRYPGGDWKPAEDTYTDANGDKAASPS 965
Query: 1002 DIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVR 1061
++ CP GW+WED+ WS D+NRAVDE+GWEY ITIPP+ KPK WV AEKMY+THRRRR VR
Sbjct: 966 ELTCPPGWEWEDDAWSYDINRAVDEKGWEYGITIPPDHKPKSWVAAEKMYHTHRRRRLVR 1025
Query: 1062 LRRRDLSQMEALKRHRQAEAEG-EGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEK 1120
R++DL+Q + E + EGWEYASL GWKFH + R +D FRRRRWRR+M P E
Sbjct: 1026 KRKKDLTQTASSTARAMEELQDQEGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSET 1085
Query: 1121 TGPAAVFALEGALGGVM----DDKS-EDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYM 1175
G AA+F LEGALG D+KS E +T FG N P +SC FD YHLRCY+
Sbjct: 1086 HGAAAIFKLEGALGADTTEDGDEKSLEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCYV 1145
Query: 1176 YQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVA 1235
YQAR+L A+DKDSFSDPYA + FLH+S+ T ++ +TLNPTWDQT+IF E+EI+GEP TV
Sbjct: 1146 YQARNLLALDKDSFSDPYAHICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQTVL 1205
Query: 1236 EQPPSIVVELYDHDTYGADEFMGRCICQP------SLERMPRLAWFPLTRGSQPSGELLA 1289
+ PP +++EL+D+D G DEF+GR I P ++ P+L W P+ G + G++L
Sbjct: 1206 QNPPKVIMELFDNDQVGKDEFLGRSIFSPVVKLNSEMDITPKLLWHPVMNGDKACGDVLV 1265
Query: 1290 SFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRT 1349
+ ELI R K + ++LP PPQR N+YMVPQ I+P +Q T
Sbjct: 1266 TAELILRGK---------------------DGSNLPILPPQRAPNLYMVPQGIRPVVQLT 1304
Query: 1350 AIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLP 1409
AIEILAWGLRNMK++Q+A+I+SPSLVVECGG+ V+S VI+NL+K PNF LFM+V LP
Sbjct: 1305 AIEILAWGLRNMKNFQMASITSPSLVVECGGERVESVVIKNLKKTPNFPSSVLFMKVFLP 1364
Query: 1410 REELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSA-ESPSPQGGPDDVSLLS 1468
+EELY PP+ +KVID+RQFGR+PVVGQCTI L+ F CDPY+ E PQ SLLS
Sbjct: 1365 KEELYMPPLVIKVIDHRQFGRKPVVGQCTIERLDRFRCDPYAGKEDIVPQ---LKASLLS 1421
Query: 1469 --PGEDVLIDIDDKEPLIPI----QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVY 1522
P D++I+++D +PL+ +EEE +DWWSKF+AS GE EKCG Y++K + LK+Y
Sbjct: 1422 APPCRDIVIEMEDTKPLLASKLTEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIY 1481
Query: 1523 DTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPR 1582
+ +LENV FEGL+DF +TFKLYRGK+ +E EDPSV+GEFKG F+IYPLP+DP++P PPR
Sbjct: 1482 NCELENVAEFEGLTDFSDTFKLYRGKS-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPPR 1540
Query: 1583 QFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEP 1642
QF +L PQEC VRIYIVR LQP+D NG CDPYIKI++GKK + D+D+YIP TL P
Sbjct: 1541 QFRELPDSVPQECTVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNP 1600
Query: 1643 VFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYC 1702
VFG+M+EL+C LP EKDLKI++YDYD ++DEK+GET++DLENR LS+FG+ CG+P+ YC
Sbjct: 1601 VFGRMYELSCYLPQEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYC 1660
Query: 1703 VSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD--RVMFQDKEYSIEEIEAGRIPNPHL 1760
VSG N WRDQLRP+QLL + P+ D R+ + ++YS++E EA +I + HL
Sbjct: 1661 VSGVNTWRDQLRPTQLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHL 1720
Query: 1761 GPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNI 1820
G EERLALH+L+ QGLVPEHVE+R L+S QP+I QGKLQMWVD+FPK+LG PGPPFNI
Sbjct: 1721 GAPEERLALHILRTQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNI 1780
Query: 1821 TPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGG 1880
TPR+A++++LR IIWNT+DVILD+ S+TGE+MSDIYVKGW+ G EE+KQKTDVHYRSL G
Sbjct: 1781 TPRKAKKYYLRVIIWNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDG 1840
Query: 1881 EGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLG 1940
EGNFNWRF+FPFDYLPAEQ+C +AKK+ FW +D+TE +IP R++ QIWDNDKFS DD+LG
Sbjct: 1841 EGNFNWRFVFPFDYLPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLG 1900
Query: 1941 SLQLDLNRMPKPAKTAKKCSLDQLDD--AFHP--EWFVSLFEQKTVKGWWPCVAEEGEKK 1996
L+LDL PAK+ +KC LD + D A +P SLFEQK++KGWWPC AE+ +
Sbjct: 1901 FLELDLRHTIIPAKSPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGAR 1960
Query: 1997 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2056
++AGK+EMTLEI+ E E +ERPAG+GRDEPNMNPKL+ P RP+TSFLWFT+P KTMKFI+
Sbjct: 1961 VMAGKVEMTLEILNEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIV 2020
Query: 2057 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2095
WRRF+W II + L ILLLF+A+ +Y+ PNY +MK+VKP
Sbjct: 2021 WRRFKWVIIGLLFLLILLLFVAVLLYSLPNYLSMKIVKP 2059
>gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens]
Length = 2093
Score = 1400 bits (3624), Expect = 0.0
Identities = 804/1970 (40%), Positives = 1126/1970 (57%), Gaps = 208/1970 (10%)
Query: 239 TSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLF 298
T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ +TRI GN+P FNE F
Sbjct: 155 TAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNPFFNEIFF 214
Query: 299 FNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPD 358
N + P + FDE I I + D+G IY P H LRKWL L P+
Sbjct: 215 QNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKWLGLCQPN 257
Query: 359 DFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFR 418
+ +G GYLK ++ LG GD+A +++K +D + + + V + A+ L ++
Sbjct: 258 NPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAYLQLFIYC 316
Query: 419 AEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT 478
AEDL K V+P +EV G+ L + + +T NP WNQ +T
Sbjct: 317 AEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILT 359
Query: 479 LPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDD----------- 527
P + ++ R++D + D + T LS+++IS+ G EIE
Sbjct: 360 FRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEPTSYTPRV 419
Query: 528 YLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQ 587
Y GFLP FGP ++ L+G + + + +G+AYRGR+ L L T++ + +
Sbjct: 420 YSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSYQDS 479
Query: 588 KVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLP 647
++DL + ++ R+EK+ R+KY L F S TM+ + + I FEVSIG+YGNK D+ P
Sbjct: 480 TIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNKMDLNYKP 538
Query: 648 LASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLE 707
L S+T YS ++DG Y+Y+PW N KPVV ++S WED+S R+ N L DRL+A L+
Sbjct: 539 LVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLD 598
Query: 708 QVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 765
LK+ + +D L +L EL C +PL + P AT LD+ +QLR+ L
Sbjct: 599 ----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQLRSLLL 654
Query: 766 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 825
+ LA K ++ + AEDWL RL + EPQ LPD++IW++ ++RVAY +
Sbjct: 655 QE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQ 709
Query: 826 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 885
VPAH VLFS GA + G+ CGK+QT+FL+YP + +P +RV +W G D K+
Sbjct: 710 VPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTDSKDLQ 769
Query: 886 QFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDSFRPSAGWTWA 944
+G +V+AE YEN+ K WG GL + P FSDV G LP F+P GW W
Sbjct: 770 LLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGWHWQ 827
Query: 945 GDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIE 1004
W V P++ LL D+D +EEV+ENQ R G W + TDVNG+ + +++++
Sbjct: 828 DSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARENVK 887
Query: 1005 CPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRR 1064
CP GW ++ ++W +LN AVD WEY + IPP P+ W P EK Y++ RRRRW R+R
Sbjct: 888 CPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWARVRF 944
Query: 1065 RDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRR 1114
R+ ++ H Q A+ E EGWEY + FG KFHL + FRRR WRRR
Sbjct: 945 RNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQSRFRRRCWRRR 999
Query: 1115 MEPLEKTGPAAVFALEGAL----GGVMDD------------------------------- 1139
+ P + G A +F LEG+L G V ++
Sbjct: 1000 LAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDLKYH 1059
Query: 1140 --KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLRCYMYQARDLA 1182
K EDS T +G++R P I C F+ + Y L CY+YQAR+L
Sbjct: 1060 AGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQARNLV 1116
Query: 1183 AMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIV 1242
+ +F P+ V FL+ SQ T ++++ PTW QTLIF + ++ P E PP +V
Sbjct: 1117 SNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTKESPPLVV 1176
Query: 1243 VELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSGELLASFELI- 1294
+EL+ D +G + GR + P + +P + W PL + + GE+LAS ELI
Sbjct: 1177 LELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEILASCELIL 1236
Query: 1295 QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEIL 1354
Q EK +P V P+ + Y +P++I+P ++R AIEIL
Sbjct: 1237 QTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQPTIKRMAIEIL 1276
Query: 1355 AWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREE 1412
AWGLRNMK SSP L+VE G +++++ IR+ + NPNF L + V++P EE
Sbjct: 1277 AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEE 1331
Query: 1413 LYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG-- 1470
Y P+ VKV+DN FG++ V GQ I L+ + CDP++ + P+ + LS
Sbjct: 1332 AYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKH 1386
Query: 1471 EDVLIDIDDK----EPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQL 1526
+D L + K + E +DWWSK F + E + Y KD+ TLKVY+ +L
Sbjct: 1387 QDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECEL 1445
Query: 1527 ENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQ 1586
E V AF+GL DFC TFKLY+ ++ D V+GEFKGLF+IYP PE+P P PP QF
Sbjct: 1446 EAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLV 1502
Query: 1587 LAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1644
+ PQ CLVR+Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+P+F
Sbjct: 1503 WPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIF 1562
Query: 1645 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1704
G MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC S
Sbjct: 1563 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQS 1622
Query: 1705 GPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LG 1761
GP +WRDQ+ PS LL + ++ + P++ D V + K++ ++ E + P H LG
Sbjct: 1623 GPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLG 1681
Query: 1762 PVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNIT 1821
P +ERLAL++L QGLVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP NI
Sbjct: 1682 PKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNIN 1741
Query: 1822 PRRAR---------RFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTD 1872
PR+ + R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+ QKTD
Sbjct: 1742 PRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTD 1801
Query: 1873 VHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDK 1932
+HY SL GE +FNWRFIF DYL AE+ C ++KD W LD T K PAR++ Q+WDND
Sbjct: 1802 IHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDI 1861
Query: 1933 FSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGW 1985
FS DDFLG L+LDL+ MP PA+ AK+CS+ +D P+W SLF++KTV GW
Sbjct: 1862 FSPDDFLGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGW 1919
Query: 1986 WPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWF 2045
WPC +G K L+GK++M+LEI++E E +PAG+G+ EPN P L P R +TSF W
Sbjct: 1920 WPCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWL 1979
Query: 2046 TSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2095
SP + +I W+R+R+ +I F+++ I+ L L FIY+ P+Y AM +KP
Sbjct: 1980 RSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 2029
Score = 61.2 bits (147), Expect = 1e-08
Identities = 41/124 (33%), Positives = 68/124 (54%), Gaps = 3/124 (2%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLR+ + A+ + P + S F +KKRT+V++ + +PVWNE W L PL+
Sbjct: 1 MLRLVVQSAK-IDPPLAPLPRPCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLE 58
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVL 119
S L V ++D + + RF+G A V L+ +L PS + + LL+ +PT ++ L
Sbjct: 59 NDSFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTL 118
Query: 120 QVSY 123
QV++
Sbjct: 119 QVAH 122
Score = 40.0 bits (92), Expect = 0.024
Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query: 269 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 328
+P + + KRTR+ +GN P++NETL ++L++ P E D + +T+ D S + +
Sbjct: 20 RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78
Query: 329 LGEFRMDVGTIYREPRHAYLRKWLLL 354
+G + + + ++P K L L
Sbjct: 79 IGLATVLLKPLLKQPSEVLFVKDLTL 104
>gi|35493868 otoferlin isoform b [Homo sapiens]
Length = 1230
Score = 720 bits (1858), Expect = 0.0
Identities = 408/1057 (38%), Positives = 584/1057 (55%), Gaps = 149/1057 (14%)
Query: 1157 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1216
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 201 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260
Query: 1217 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1269
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 261 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320
Query: 1270 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1326
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 321 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360
Query: 1327 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1383
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 361 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420
Query: 1384 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1443
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 421 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480
Query: 1444 SFLCDPYSAESPSPQGGPDDVSLLSPG---------------EDVLIDID---------- 1478
F+ P +PS + V + P + ++ +D
Sbjct: 481 RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540
Query: 1479 -----DKEPLIPIQEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1515
+EP +E +DWWSK+FASI ++E G LE+
Sbjct: 541 KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600
Query: 1516 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1538
D LKVY +LE+ F+ D+
Sbjct: 601 SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658
Query: 1539 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1588
+TF L RGKT ++ TE+ ++G FKG +Y PLPED + F +
Sbjct: 659 LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718
Query: 1589 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1648
+ P LVR+Y+VRA L P D NGK DPYI I +GK + D++NYI L PVFGK F
Sbjct: 719 SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778
Query: 1649 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1708
++ + P+E L + +YD+DL+ D+ IGET +DLENR SK A CG+ QTY G N
Sbjct: 779 DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838
Query: 1709 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1766
WRD ++PSQ+L C+ +V P + RV ++ ++ EIE N P +E
Sbjct: 839 WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895
Query: 1767 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1818
+AL L+ LVPEHVE+RPL +P +P IEQG+L++WVD+FP + PG P
Sbjct: 896 VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955
Query: 1819 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1877
+I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V+GW+ G +E KQ TDVHY S
Sbjct: 956 DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015
Query: 1878 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1937
L GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE KIPAR+ QIWD D FS DD
Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075
Query: 1938 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 1996
FLG+++LDLNR P+ AKTAK+C+++ VS+F+QK VKGWWP +A E ++
Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134
Query: 1997 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2056
L GK+E L ++ E E+ P G R+EP+ LE P RPDTSF+WF +P K+ ++ L
Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTSFIWFLNPLKSARYFL 1191
Query: 2057 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2093
W +RW ++ ++L +LLL LA+F+Y+ P Y K++
Sbjct: 1192 WHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1228
Score = 87.4 bits (215), Expect = 1e-16
Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%)
Query: 731 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 785
+EL GC + L D + S+ T LD+ + L + + A L+ + +
Sbjct: 18 EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77
Query: 786 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 845
L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C
Sbjct: 78 LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136
Query: 846 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 884
K++T+FLK P ++ G A VQ +V+ LW GLS KEF
Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 439 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 475
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262
>gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens]
Length = 802
Score = 714 bits (1842), Expect = 0.0
Identities = 366/746 (49%), Positives = 494/746 (66%), Gaps = 32/746 (4%)
Query: 1370 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1427
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
Query: 1428 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----E 1481
FG++ V GQ I L+ + CDP++ + P+ + LS +D L + K
Sbjct: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKS 119
Query: 1482 PLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNT 1541
+ E +DWWSK F + E + Y KD+ TLKVY+ +LE V AF+GL DFC T
Sbjct: 120 SKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQT 178
Query: 1542 FKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRI 1599
FKLY+ ++ D V+GEFKGLF+IYP PE+P P PP QF + PQ CLVR+
Sbjct: 179 FKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRV 235
Query: 1600 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1659
Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+P+FG MFELTC +PLEKD
Sbjct: 236 YMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKD 295
Query: 1660 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1719
L+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL
Sbjct: 296 LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLL 355
Query: 1720 HLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQG 1776
+ ++ + P++ D V + K++ ++ E + P H LGP +ERLAL++L QG
Sbjct: 356 ERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQG 414
Query: 1777 LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWN 1836
LVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP NI PR+ +R+ LRCIIW
Sbjct: 415 LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474
Query: 1837 TRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLP 1896
T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL
Sbjct: 475 TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534
Query: 1897 AEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTA 1956
AE+ C ++KD W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ A
Sbjct: 535 AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594
Query: 1957 KKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 2009
K+CS+ +D P+W SLF++KTV GWWPC +G K L+GK++M+LEI+
Sbjct: 595 KQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEIL 652
Query: 2010 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2069
+E E +PAG+G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F++
Sbjct: 653 SEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMV 712
Query: 2070 LFILLLFLAIFIYAFPNYAAMKLVKP 2095
+ I+ L L FIY+ P+Y AM +KP
Sbjct: 713 ISIIALMLFNFIYSAPHYLAMSWIKP 738
>gi|35493853 otoferlin isoform c [Homo sapiens]
Length = 1307
Score = 712 bits (1839), Expect = 0.0
Identities = 410/1077 (38%), Positives = 584/1077 (54%), Gaps = 169/1077 (15%)
Query: 1157 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1216
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 258 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 317
Query: 1217 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1269
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 318 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 377
Query: 1270 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1326
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 378 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 417
Query: 1327 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1383
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 418 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 477
Query: 1384 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1443
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 478 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 537
Query: 1444 SFLCDPYSAESPS--------------PQGGPDDVSL---------------------LS 1468
F+ P +PS GG S L
Sbjct: 538 RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGSSSHSTGEVVVTMEPEVPIKKLETMVKLD 597
Query: 1469 PGEDVLIDID---------------DKEPLIPIQEEEFIDWWSKFFASIG-------ERE 1506
+ ++ +D +EP +E +DWWSK+FASI ++E
Sbjct: 598 ATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQE 657
Query: 1507 KCGSYLEKD------------------------------------------------FDT 1518
G LE+ D
Sbjct: 658 PSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDE 717
Query: 1519 LKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLP 1572
LKVY +LE+ F+ D+ +TF L RGKT ++ TE+ ++G FKG +Y PLP
Sbjct: 718 LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 775
Query: 1573 EDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKS 1628
ED + F + + P LVR+Y+VRA L P D NGK DPYI I +GK
Sbjct: 776 EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 835
Query: 1629 VSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLL 1688
+ D++NYI L PVFGK F++ + P+E L + +YD+DL+ D+ IGET +DLENR
Sbjct: 836 IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 895
Query: 1689 SKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS- 1746
SK A CG+ QTY G N WRD ++PSQ+L C+ +V P + RV ++ ++
Sbjct: 896 SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 955
Query: 1747 IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQG 1798
EIE N P +E +AL L+ LVPEHVE+RPL +P +P IEQG
Sbjct: 956 PSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQG 1012
Query: 1799 KLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYV 1857
+L++WVD+FP + PG P +I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V
Sbjct: 1013 RLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFV 1072
Query: 1858 KGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTES 1917
+GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE
Sbjct: 1073 RGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEY 1132
Query: 1918 KIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLF 1977
KIPAR+ QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++ VS+F
Sbjct: 1133 KIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIF 1191
Query: 1978 EQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2036
+QK VKGWWP +A E ++ L GK+E L ++ E E+ P G R+EP+ LE P
Sbjct: 1192 KQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPN 1248
Query: 2037 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2093
RPDTSF+WF +P K+ ++ LW +RW ++ ++L +LLL LA+F+Y+ P Y K++
Sbjct: 1249 RPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1305
Score = 91.3 bits (225), Expect = 9e-18
Identities = 71/211 (33%), Positives = 110/211 (52%), Gaps = 21/211 (9%)
Query: 682 WEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQ-- 739
W I+H ++Q E GL + +K + S + + + +EL GC +
Sbjct: 38 WPSITHTPDSQ----------EEGLNDIQEMIKTEKSYPE--RRLRGVLEELSCGCCRFL 85
Query: 740 PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAALEQAEDWLLRL 796
L D + S+ T LD+ + L + + A L+ + + L +++L +L
Sbjct: 86 SLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKL 145
Query: 797 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 856
R LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C K++T+FLK P
Sbjct: 146 RFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDCAKVKTLFLKLP 204
Query: 857 MEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 884
++ G A VQ +V+ LW GLS KEF
Sbjct: 205 GKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 235
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 439 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 475
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 283 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 319
>gi|35493860 otoferlin isoform d [Homo sapiens]
Length = 1230
Score = 712 bits (1839), Expect = 0.0
Identities = 406/1057 (38%), Positives = 583/1057 (55%), Gaps = 149/1057 (14%)
Query: 1157 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1216
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 201 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260
Query: 1217 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1269
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 261 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320
Query: 1270 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1326
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 321 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360
Query: 1327 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1383
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 361 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420
Query: 1384 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1443
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 421 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480
Query: 1444 SFLCDPYSAESPSPQGGPDDVSLLSPG---------------EDVLIDID---------- 1478
F+ P +PS + V + P + ++ +D
Sbjct: 481 RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540
Query: 1479 -----DKEPLIPIQEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1515
+EP +E +DWWSK+FASI ++E G LE+
Sbjct: 541 KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600
Query: 1516 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1538
D LKVY +LE+ F+ D+
Sbjct: 601 SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658
Query: 1539 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1588
+TF L RGKT ++ TE+ ++G FKG +Y PLPED + F +
Sbjct: 659 LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718
Query: 1589 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1648
+ P LVR+Y+VRA L P D NGK DPYI I +GK + D++NYI L PVFGK F
Sbjct: 719 SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778
Query: 1649 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1708
++ + P+E L + +YD+DL+ D+ IGET +DLENR SK A CG+ QTY G N
Sbjct: 779 DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838
Query: 1709 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1766
WRD ++PSQ+L C+ +V P + RV ++ ++ EIE N P +E
Sbjct: 839 WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895
Query: 1767 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1818
+AL L+ LVPEHVE+RPL +P +P IEQG+L++WVD+FP + PG P
Sbjct: 896 VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955
Query: 1819 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1877
+I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V+GW+ G +E KQ TDVHY S
Sbjct: 956 DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015
Query: 1878 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1937
L GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE KIPAR+ QIWD D FS DD
Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075
Query: 1938 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 1996
FLG+++LDLNR P+ AKTAK+C+++ VS+F+QK VKGWWP +A E ++
Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134
Query: 1997 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2056
L GK+E L ++ E E+ P G R+EP+ LE P RPDT+F+WF +P K++K+++
Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTAFVWFLNPLKSIKYLI 1191
Query: 2057 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2093
R++W II ++ + LL L +F+Y+ P Y KL+
Sbjct: 1192 CTRYKWLIIKIVLALLGLLMLGLFLYSLPGYMVKKLL 1228
Score = 87.4 bits (215), Expect = 1e-16
Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%)
Query: 731 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 785
+EL GC + L D + S+ T LD+ + L + + A L+ + +
Sbjct: 18 EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77
Query: 786 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 845
L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C
Sbjct: 78 LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136
Query: 846 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 884
K++T+FLK P ++ G A VQ +V+ LW GLS KEF
Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 439 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 475
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262
>gi|34740331 otoferlin isoform a [Homo sapiens]
Length = 1997
Score = 712 bits (1839), Expect = 0.0
Identities = 410/1077 (38%), Positives = 584/1077 (54%), Gaps = 169/1077 (15%)
Query: 1157 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1216
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 948 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 1007
Query: 1217 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1269
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 1008 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 1067
Query: 1270 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1326
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 1068 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 1107
Query: 1327 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1383
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 1108 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 1167
Query: 1384 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1443
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 1168 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 1227
Query: 1444 SFLCDPYSAESPS--------------PQGGPDDVSL---------------------LS 1468
F+ P +PS GG S L
Sbjct: 1228 RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGSSSHSTGEVVVTMEPEVPIKKLETMVKLD 1287
Query: 1469 PGEDVLIDID---------------DKEPLIPIQEEEFIDWWSKFFASIG-------ERE 1506
+ ++ +D +EP +E +DWWSK+FASI ++E
Sbjct: 1288 ATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQE 1347
Query: 1507 KCGSYLEKD------------------------------------------------FDT 1518
G LE+ D
Sbjct: 1348 PSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDE 1407
Query: 1519 LKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLP 1572
LKVY +LE+ F+ D+ +TF L RGKT ++ TE+ ++G FKG +Y PLP
Sbjct: 1408 LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 1465
Query: 1573 EDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKS 1628
ED + F + + P LVR+Y+VRA L P D NGK DPYI I +GK
Sbjct: 1466 EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 1525
Query: 1629 VSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLL 1688
+ D++NYI L PVFGK F++ + P+E L + +YD+DL+ D+ IGET +DLENR
Sbjct: 1526 IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 1585
Query: 1689 SKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS- 1746
SK A CG+ QTY G N WRD ++PSQ+L C+ +V P + RV ++ ++
Sbjct: 1586 SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 1645
Query: 1747 IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQG 1798
EIE N P +E +AL L+ LVPEHVE+RPL +P +P IEQG
Sbjct: 1646 PSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQG 1702
Query: 1799 KLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYV 1857
+L++WVD+FP + PG P +I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V
Sbjct: 1703 RLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFV 1762
Query: 1858 KGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTES 1917
+GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE
Sbjct: 1763 RGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEY 1822
Query: 1918 KIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLF 1977
KIPAR+ QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++ VS+F
Sbjct: 1823 KIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIF 1881
Query: 1978 EQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2036
+QK VKGWWP +A E ++ L GK+E L ++ E E+ P G R+EP+ LE P
Sbjct: 1882 KQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPN 1938
Query: 2037 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2093
RPDTSF+WF +P K+ ++ LW +RW ++ ++L +LLL LA+F+Y+ P Y K++
Sbjct: 1939 RPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1995
Score = 392 bits (1007), Expect = e-108
Identities = 295/942 (31%), Positives = 469/942 (49%), Gaps = 112/942 (11%)
Query: 21 DAYCSAVFAGVKKRTKVIKNSVNPV-WNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNR 79
D F G ++V++N + ++E F W + +D+ L + V ++ + N+
Sbjct: 18 DRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVAS-SIDRNEMLEIQVFNYSKVFSNK 76
Query: 80 FLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPPPTPL 139
+G ++ L++V+ + + L+D SL ++V Y G V + L
Sbjct: 77 LIGTFRMVLQKVVEESHVEVTDT--LIDDNNAIIKTSLCVEVRYQATDGTVGSWDDGDFL 134
Query: 140 ------EPSPTLPDLDVVAGGGQS----------RAETWSLLSDSTMDTRYSGKKWPAPT 183
E + D + G + R S+ S + S K+ P
Sbjct: 135 GDESLQEEEKDSQETDGLLPGSRPSSRPPGEKSFRRAGRSVFSAMKLGKNRSHKEEPQRP 194
Query: 184 DTGGEEDTEDQG----LTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 239
D + ED GD +P A TT + KRS P
Sbjct: 195 DEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTT-------------NVSNKRSKPD 241
Query: 240 SRKLLS-DKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNETL 297
+ S +P D+Q+ + VIE RQL G+N+ PVV V K T + + N P +NE
Sbjct: 242 IKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYF 301
Query: 298 FFNLFDSPGELFDEPIFITVVDSRSL-RTDALLGEFRMDVGTIYREPRHAYLRKWLLLSD 356
F+ SP +FD+ I I+V+ S++L R+ L+G F+MDVGT+Y +P H + KW +LSD
Sbjct: 302 VFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSD 361
Query: 357 PDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGV--ALRGAHFCL 414
PDD S+G +GY+K + V+G GD K D++DIE NLL P GV + A F +
Sbjct: 362 PDDISSGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYV 421
Query: 415 KVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWN 474
K++RAE LP+M+ ++M NVK+ F E+ K+LVDP+V+V FAG+ + + + + P WN
Sbjct: 422 KIYRAEGLPRMNTSLMANVKKAFIGEN--KDLVDPYVQVFFAGQKGKTSVQKSSYEPLWN 479
Query: 475 QNITLPAMFPSMCEKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEVDDYLGFLP 533
+ + +FP +C++M+++I D D++ ND+ + T ++ + KIS G + GFLP
Sbjct: 480 EQVVFTDLFPPLCKRMKVQIRDSDKV--NDVAIGTHFIDLRKISNDGDK-------GFLP 530
Query: 534 TFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLP 593
T GP ++N+YGS R +T D + +LN G GEGV++R RLLL L ++V+ S +L
Sbjct: 531 TLGPAWVNMYGSTRNYT-LLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSN---PELT 586
Query: 594 ADDILRVEKYL--------RRRKYSLFAAFYSATML--QDVDDAIQFEVSIGNYGNKFDM 643
+ ++VE+ + ++ LF AF A+M+ ++ D I FEV+IGNYGN+ D
Sbjct: 587 SSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDRRNGDKPITFEVTIGNYGNEVDG 646
Query: 644 TCLP---------------------------------LASTTQYSRAVFDGCHYYYLPWG 670
P S+T R +Y++LP+
Sbjct: 647 LSRPQRPRPRKEPGDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVTDRNYFHLPYL 706
Query: 671 NVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLT 730
KP + + S+W D R+ N + IAD+LE GL + +K + S + + +
Sbjct: 707 ERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYP--ERRLRGVL 764
Query: 731 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAA--LALKLGHSELPAA 785
+EL GC + L D + S+ T LD+ + L + + A L ++ +
Sbjct: 765 EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 824
Query: 786 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 845
L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C
Sbjct: 825 LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 883
Query: 846 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 884
K++T+FLK P ++ G A VQ +V+ LW GLS KEF
Sbjct: 884 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 925
Score = 35.4 bits (80), Expect = 0.59
Identities = 15/31 (48%), Positives = 19/31 (61%)
Query: 18 DISDAYCSAVFAGVKKRTKVIKNSVNPVWNE 48
D+ D Y FAG K +T V K+S P+WNE
Sbjct: 450 DLVDPYVQVFFAGQKGKTSVQKSSYEPLWNE 480
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 439 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 475
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 973 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 1009
Score = 32.3 bits (72), Expect = 5.0
Identities = 13/35 (37%), Positives = 21/35 (60%)
Query: 1191 DPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1225
DPY V F Q KT V K++ P W++ ++F ++
Sbjct: 453 DPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDL 487
>gi|119120884 fer-1-like 6 [Homo sapiens]
Length = 1857
Score = 709 bits (1830), Expect = 0.0
Identities = 405/1085 (37%), Positives = 580/1085 (53%), Gaps = 172/1085 (15%)
Query: 1147 VSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTV 1206
+S+ G N P + ++ + + LR +MYQAR L A D + SDP+A V+FL Q T
Sbjct: 804 MSSKGAGTNHPPSNLLYQEQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSHCQTTK 863
Query: 1207 VVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL 1266
++ TL+PTW+Q L+F ++ + G+ +AE PP +VVELYD D G E++G + P +
Sbjct: 864 IISQTLSPTWNQMLLFNDLVLHGDVKELAESPPLVVVELYDSDAVGKPEYLGATVAAPVV 923
Query: 1267 E------RMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1320
+ PRL + P+ G+ G+LLA FEL+Q + +P
Sbjct: 924 KLADQDYEPPRLCYHPIFCGNLSGGDLLAVFELLQVPPSGLQGLP--------------- 968
Query: 1321 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1380
P PP IY VP NI+P L + +E+L WG+R MK QL ++ P ++ECGG
Sbjct: 969 ----PVEPPDI-TQIYPVPANIRPVLSKYRVEVLFWGVREMKKVQLLSVDRPQALIECGG 1023
Query: 1381 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1440
Q V+SCVI++ + NPNF I EV LP EL PP+++ V+D R FGR +VG TI
Sbjct: 1024 QGVKSCVIQSYKNNPNFSIQADAFEVELPENELLHPPLSICVVDWRAFGRSTLVGTYTIN 1083
Query: 1441 SLESFLC--------------------------------------DP-----YSAESPSP 1457
L+ FLC DP Y P P
Sbjct: 1084 YLKQFLCKLREPLAPITQVDGTQPGHDISDSLTATESSGAHSSSQDPPADHIYVDVEPPP 1143
Query: 1458 QGGPDDVSLLSPGEDVLIDIDDKEPLI-----PIQEE----------------------- 1489
PD +L+D+ D P++ P+ +E
Sbjct: 1144 TVVPDSAQAQPA---ILVDVPDSSPMLEPEHTPVAQEPPKDGKPKDPRKPSRRSTKRRKR 1200
Query: 1490 --------EFIDWWSKFFASI-------------------------------GEREKCGS 1510
IDWWSK++AS+ G ++K
Sbjct: 1201 TIADESAENVIDWWSKYYASLKKAQKAKERNPKGKKGNTEAKPDEVVVDIEDGPKKKKDK 1260
Query: 1511 YLEK--------DFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEET---EDPSVI 1559
L+K + L++YD LE+ F D+ TF+L+RGK+ E+ + VI
Sbjct: 1261 MLKKKPKDDGIPNLAILQIYDGDLES--EFNNFEDWVKTFELFRGKSTEDDHGLDGDRVI 1318
Query: 1560 GEFKGLFKIYPLPEDPAIPMPPRQFHQ--LAAQGPQECLVRIYIVRAFGLQPKDPNGKCD 1617
G+FKG F IY P+D + + Q + P L+R+YIV AF L P DP+GK D
Sbjct: 1319 GKFKGSFCIYKSPQDSSSEDSGQLRIQQGIPPNHPVTVLIRVYIVAAFNLSPADPDGKSD 1378
Query: 1618 PYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIG 1677
PYI I +GK + D+D YIP L PVFG+ FE+ T P E L I +YD+D++ D+ IG
Sbjct: 1379 PYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSILIYDHDMIGTDDLIG 1438
Query: 1678 ETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDR 1737
ET +DLENR SK A CGL Y + G N WRD +P+++L C+ +++ P + +
Sbjct: 1439 ETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYFHPGK 1498
Query: 1738 VMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYS 1789
+ ++ +S + I + + E LAL VL LVPEH+E+RPLY
Sbjct: 1499 IQIGNQVFSGKTIFTEEDTDETVESYEH-LALKVLHSWEDIPEVGCRLVPEHIETRPLYH 1557
Query: 1790 PLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSL-T 1848
+P +EQG+LQMWVD+FPK + +PGPP +I+PRR + + LR IWNT DVIL+D ++ T
Sbjct: 1558 KDKPGMEQGRLQMWVDMFPKDMPQPGPPVDISPRRPKGYELRVTIWNTEDVILEDENIFT 1617
Query: 1849 GEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDA 1908
G+K SDIYVKGW+ G E+ KQ+TDVHY SL GEGNFNWRF+FPF YLPAE+ I K++
Sbjct: 1618 GQKSSDIYVKGWLKGLEDDKQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVITKREN 1677
Query: 1909 FWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAF 1968
+ L+K E K PA +V Q+WD ++ S DDFLG+L+++LN P+ AK+AK C L + ++A
Sbjct: 1678 IFSLEKMECKTPAVLVLQVWDFERLSSDDFLGTLEMNLNSFPRAAKSAKACDLAKFENA- 1736
Query: 1969 HPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNM 2028
E +S+F+QK V+GWWP + K L GK+E +V E E+ P G+ R EP
Sbjct: 1737 SEETKISIFQQKRVRGWWPF----SKSKELTGKVEAEFHLVTAEEAEKNPVGKARKEPE- 1791
Query: 2029 NPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYA 2088
L P RPDTSF WF SP+K + +++W+ ++ II+ IL IL++FL +FIY P
Sbjct: 1792 --PLAKPNRPDTSFSWFMSPFKCLYYLIWKNYKKYIIIAFILIILIIFLVLFIYTLPGAI 1849
Query: 2089 AMKLV 2093
+ ++V
Sbjct: 1850 SRRIV 1854
Score = 348 bits (893), Expect = 3e-95
Identities = 236/724 (32%), Positives = 372/724 (51%), Gaps = 112/724 (15%)
Query: 247 KPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNETLFFNLFDSP 305
+ Q++QI + + E RQL G NI PVV + + K++ + +G NSP +NE F+
Sbjct: 79 RSQNYQIAITITEARQLVGENIDPVVTIEIGDEKKQSTVKEGTNSPFYNEYFVFDFIGPQ 138
Query: 306 GELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGAR 365
LFD+ I I+V + + + L+G F++D+GT+Y +P H + KW LL+DP D G +
Sbjct: 139 VHLFDKIIKISVFHHKLIGS-VLIGSFKVDLGTVYNQPGHQFCNKWALLTDPGDIRTGTK 197
Query: 366 GYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALR--GAHFCLKVFRAEDLP 423
GYLK + V+G GD K S+ +E IE NLL P G L A F +++++AE LP
Sbjct: 198 GYLKCDISVMGKGDVLKTSPK-TSDTEEPIEKNLLIPNGFPLERPWARFYVRLYKAEGLP 256
Query: 424 QMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMF 483
+M+ ++M NV + F + K+LVDPFVEVSFAG+M + + + A+P W++ + MF
Sbjct: 257 KMNSSIMANVTK--AFVGDSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEMF 314
Query: 484 PSMCEKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYINL 542
P +C +++I++ WD + ND+ +AT ++ + KIS E D GFLPTFGP +INL
Sbjct: 315 PPLCRRVKIQV--WDEGSMNDVALATHFIDLKKISN-----EQDGDKGFLPTFGPAWINL 367
Query: 543 YGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQ--------KVEDLPA 594
YGSPR + D Y E+N G GEGV++RGR+L+ + +++ Q K LP+
Sbjct: 368 YGSPRNHS-LMDDYQEMNEGFGEGVSFRGRILVEIAVEILSGRAQESKFSKALKELKLPS 426
Query: 595 DD------------------------------ILRVEKY--------LRRRKYSLFAAFY 616
D + VE + + ++ LF AF+
Sbjct: 427 KDKDSKSSKGKDKADKTEDGKSQQASNKTNSTEVEVESFDVPPEIVPEKNEEFLLFGAFF 486
Query: 617 SATMLQDV--DDAIQFEVSIGNYGNKFD-------------------------------M 643
ATM+ D I FEVSIGN+GN D
Sbjct: 487 EATMIDRKIGDKPISFEVSIGNFGNLIDGGSHHGSKKSAESAEEDLLPLLHEGQGDVAHD 546
Query: 644 TCLPLASTTQYSRAVF--DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADR 701
+P+ASTT + + +Y YLP+ KP V S W D + R+ N L +AD
Sbjct: 547 VPIPMASTTHPEKPLVTEGNRNYNYLPFEAKKPCVYFISSWGDQTFRLHWSNMLEKMADF 606
Query: 702 LEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETP---SATHLDQYLY 758
LE +E+V +K S E + + + + I+ S + + + P + T LD+
Sbjct: 607 LEESIEEVRELIK--ISQEAPEEKMKTVLSDFISRSSAFISEAEKKPKMLNQTTLDKKRL 664
Query: 759 QLRTHHLSQITEAALAL------KLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVI 812
L L + + A + KL E+ + +A++++ ++R L +EPQ+++PD+ I
Sbjct: 665 TLCWQELEAMCKEAKGIIQQQKKKLSVDEM---IHEAQNFVEKIRFLVDEPQHTIPDVFI 721
Query: 813 WMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVK 872
WML ++RVAY R+ + +L+S A GK+CGK++T FLK P ++ G + ++ V
Sbjct: 722 WMLSNNRRVAYARIASKDLLYS-PVAGQMGKHCGKIKTHFLKPPGKRPAGWSVQAKVDVY 780
Query: 873 LWFG 876
LW G
Sbjct: 781 LWLG 784
Score = 41.2 bits (95), Expect = 0.011
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
Query: 1 MLRVFILYAENVHTPDTD-ISDAYCSAVFAG--VKKRTKVIKNSVNPVWNEGFEWDLKGI 57
++RV+I+ A N+ D D SD Y +K R K I +NPV+ FE
Sbjct: 1357 LIRVYIVAAFNLSPADPDGKSDPYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQAT-- 1414
Query: 58 PLDQGSELHVVVKDHETMGRNRFLGEAKVPL 88
+ S L +++ DH+ +G + +GE K+ L
Sbjct: 1415 -FPKESLLSILIYDHDMIGTDDLIGETKIDL 1444
Score = 35.8 bits (81), Expect = 0.45
Identities = 16/41 (39%), Positives = 22/41 (53%)
Query: 1185 DKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1225
D DP+ VSF Q +T V KN +P W + +IF E+
Sbjct: 273 DSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEM 313
Score = 34.3 bits (77), Expect = 1.3
Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 8/93 (8%)
Query: 441 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ-----NITLPAMFPSMCEKMRIRII 495
++ L DPF +V+F +KI+ +T +P WNQ ++ L + E + ++
Sbjct: 841 ADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQMLLFNDLVLHGDVKELAESPPLVVV 900
Query: 496 DWDRLTHNDIVATTYLSMSKISAPGGEIEVDDY 528
+ L +D V + ++AP ++ DY
Sbjct: 901 E---LYDSDAVGKPEYLGATVAAPVVKLADQDY 930
Score = 32.0 bits (71), Expect = 6.5
Identities = 14/31 (45%), Positives = 18/31 (58%)
Query: 18 DISDAYCSAVFAGVKKRTKVIKNSVNPVWNE 48
D+ D + FAG RT V KN +PVW+E
Sbjct: 276 DLVDPFVEVSFAGQMGRTTVQKNCADPVWHE 306
>gi|4759026 RAS protein activator like 1 [Homo sapiens]
Length = 804
Score = 65.5 bits (158), Expect = 5e-10
Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 13/127 (10%)
Query: 1171 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1230
LRC++ ARDLA D SDP+A V + QS +T +K T P WD+ L E
Sbjct: 135 LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVL---------E 185
Query: 1231 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQP-SLERMPRLAWF---PLTRGSQPSGE 1286
+ P + VEL+D D G ++F+G P +L++ P WF P R + SG
Sbjct: 186 LREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAEEDSGG 245
Query: 1287 LLASFEL 1293
L + +
Sbjct: 246 NLGALRV 252
Score = 43.9 bits (102), Expect = 0.002
Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 13/167 (7%)
Query: 1511 YLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYP 1570
+L DF L Y + V G D L R + T DP I + L ++ P
Sbjct: 60 HLPLDFHQLAFYVLDEDTV----GHDDIIGKISLSR---EAITADPRGIDSWINLSRVDP 112
Query: 1571 LPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVS 1630
D + Q+ G CL R +++ A L P+D +G DP+ ++ G +S+
Sbjct: 113 ---DAEVQGEICLSVQMLEDGQGRCL-RCHVLHARDLAPRDISGTSDPFARVFWGSQSL- 167
Query: 1631 DQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIG 1677
+ + I T P + ++ EL L++ L+D+D++ K++ +G
Sbjct: 168 -ETSTIKKTRFPHWDEVLELREMPGAPSPLRVELWDWDMVGKNDFLG 213
Score = 43.5 bits (101), Expect = 0.002
Identities = 59/268 (22%), Positives = 100/268 (37%), Gaps = 64/268 (23%)
Query: 253 IRVQVIEGRQLPGVNIKP------VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPG 306
+ V+V+EGR LP ++ +VKV + + + P + E +L
Sbjct: 7 LNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVHL----- 61
Query: 307 ELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLS--DPDDFSAGA 364
L + V+D ++ D ++G+ + I +PR + W+ LS DPD A
Sbjct: 62 PLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRG--IDSWINLSRVDPD---AEV 116
Query: 365 RGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQ 424
+G + S+ +L ED + LR V A DL
Sbjct: 117 QGEICLSVQML-----------------EDGQGRCLR------------CHVLHARDLAP 147
Query: 425 MDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFP 484
D + DPF V + + L + ++KT P W++ + L M P
Sbjct: 148 RDIS----------------GTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREM-P 190
Query: 485 SMCEKMRIRIIDWDRLTHNDIVATTYLS 512
+R+ + DWD + ND + S
Sbjct: 191 GAPSPLRVELWDWDMVGKNDFLGMVEFS 218
Score = 33.9 bits (76), Expect = 1.7
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 2 LRVFILYAENVHTPD-TDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEW-DLKGIPL 59
LR +L+A ++ D + SD + + T IK + P W+E E ++ G P
Sbjct: 135 LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGAP- 193
Query: 60 DQGSELHVVVKDHETMGRNRFLG 82
S L V + D + +G+N FLG
Sbjct: 194 ---SPLRVELWDWDMVGKNDFLG 213
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 54.3 bits (129), Expect = 1e-06
Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%)
Query: 1144 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1188
S SVS G ++PT + +D GN L ++ QAR+L D +
Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726
Query: 1189 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1234
+SDP+ V L + +VV+N +LNP W+QT+I+ I +
Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780
Query: 1235 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1288
+ ++ V ++D+D + +++F+G + S L+ PR W+PL ++ G+
Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838
Query: 1289 ASFELIQREKPAI 1301
+S Q KP++
Sbjct: 4839 SSQSSQQSPKPSV 4851
Score = 43.5 bits (101), Expect = 0.002
Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%)
Query: 1599 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1646
I+I++A L P+D NG DP++K+ + G+ V N ++ +L P + +
Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770
Query: 1647 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1685
++ +K L++T++DYD S ++ +GE ++DL +
Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812
Score = 41.6 bits (96), Expect = 0.008
Identities = 43/145 (29%), Positives = 62/145 (42%), Gaps = 21/145 (14%)
Query: 29 AGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKV 86
A K+RTK ++ S+NP WN+ + K I ++Q L V V D++ N FLGE +
Sbjct: 4751 AEYKRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLI 4808
Query: 87 PLREVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPP 135
L S S N P K+ T G S Q S +P P + +FP
Sbjct: 4809 DL------SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPD 4862
Query: 136 PTPLEPSPTLPDLDVVAGGGQSRAE 160
P+ PT+ G +S +E
Sbjct: 4863 PSKDMQVPTIEKSHSSPGSSKSSSE 4887
Score = 36.6 bits (83), Expect = 0.27
Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Query: 462 SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 517
+K ++K+ NP+WNQ + ++ +K + + + D+DR + ND + + +S S
Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814
Score = 34.7 bits (78), Expect = 1.0
Identities = 53/211 (25%), Positives = 74/211 (35%), Gaps = 35/211 (16%)
Query: 109 KKQPTGASLVLQVSYTPLPGAVPLFP-PPTPLEPSPTLPDLDVVAGGG---QSRAETWSL 164
K++P A Q +P P A P+ PTP P PT Q ++ +SL
Sbjct: 852 KEEPKKA----QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSL 907
Query: 165 LSDSTMDTRYSGKKWPAPTDTG------GEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPR 218
S D S P T TG ++ L +P GPGAP
Sbjct: 908 NLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA 967
Query: 219 KLPSRPP------------PHYPG----IKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQ 262
PS+PP P P +K++ AP + KL Q ++ E +
Sbjct: 968 PAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP 1027
Query: 263 LPGVNIKPVVKVTAAGQ--TKRTRIHKGNSP 291
P IK +TA Q T++ K P
Sbjct: 1028 PP---IKDSKSLTAEPQKAVLPTKLEKSPKP 1055
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 54.3 bits (129), Expect = 1e-06
Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%)
Query: 1144 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1188
S SVS G ++PT + +D GN L ++ QAR+L D +
Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726
Query: 1189 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1234
+SDP+ V L + +VV+N +LNP W+QT+I+ I +
Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780
Query: 1235 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1288
+ ++ V ++D+D + +++F+G + S L+ PR W+PL ++ G+
Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838
Query: 1289 ASFELIQREKPAI 1301
+S Q KP++
Sbjct: 4839 SSQSSQQSPKPSV 4851
Score = 43.5 bits (101), Expect = 0.002
Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%)
Query: 1599 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1646
I+I++A L P+D NG DP++K+ + G+ V N ++ +L P + +
Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770
Query: 1647 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1685
++ +K L++T++DYD S ++ +GE ++DL +
Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812
Score = 43.5 bits (101), Expect = 0.002
Identities = 58/214 (27%), Positives = 82/214 (38%), Gaps = 39/214 (18%)
Query: 29 AGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKV 86
A K+RTK ++ S+NP WN+ + K I ++Q L V V D++ N FLGE +
Sbjct: 4751 AEYKRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLI 4808
Query: 87 PLREVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPP 135
L S S N P K+ T G S Q S +P P + +FP
Sbjct: 4809 DL------SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPD 4862
Query: 136 PTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWPAPTDTGGEEDTEDQG 195
P+ PT+ +S + S S S R G + + ED G
Sbjct: 4863 PSKDMQVPTIE---------KSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAG 4913
Query: 196 LTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYP 229
AE + Q R P++PP H P
Sbjct: 4914 AAIAAAEAAVQQL---------RIQPTKPPNHRP 4938
Score = 36.6 bits (83), Expect = 0.27
Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Query: 462 SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 517
+K ++K+ NP+WNQ + ++ +K + + + D+DR + ND + + +S S
Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814
Score = 34.7 bits (78), Expect = 1.0
Identities = 53/211 (25%), Positives = 74/211 (35%), Gaps = 35/211 (16%)
Query: 109 KKQPTGASLVLQVSYTPLPGAVPLFP-PPTPLEPSPTLPDLDVVAGGG---QSRAETWSL 164
K++P A Q +P P A P+ PTP P PT Q ++ +SL
Sbjct: 852 KEEPKKA----QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSL 907
Query: 165 LSDSTMDTRYSGKKWPAPTDTG------GEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPR 218
S D S P T TG ++ L +P GPGAP
Sbjct: 908 NLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA 967
Query: 219 KLPSRPP------------PHYPG----IKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQ 262
PS+PP P P +K++ AP + KL Q ++ E +
Sbjct: 968 PAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP 1027
Query: 263 LPGVNIKPVVKVTAAGQ--TKRTRIHKGNSP 291
P IK +TA Q T++ K P
Sbjct: 1028 PP---IKDSKSLTAEPQKAVLPTKLEKSPKP 1055
>gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo
sapiens]
Length = 778
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)
Query: 1175 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1234
+ + RDL AMD + SDPY HQ K+ ++ TLNP W + F+ E
Sbjct: 255 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 306
Query: 1235 AEQPPSIVVELYDHDTYGADEFMGRC 1260
E+ I + +D D D+F+GRC
Sbjct: 307 -ERGGVIDITAWDKDAGKRDDFIGRC 331
Score = 42.7 bits (99), Expect = 0.004
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 1596 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1655
+V I ++ L+ D NG DPY+K +G + + +P TL P + + F+
Sbjct: 250 IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 307
Query: 1656 LEKDLKITLYDYDLLSKDEKIGETVVDL 1683
+ IT +D D +D+ IG VDL
Sbjct: 308 RGGVIDITAWDKDAGKRDDFIGRCQVDL 335
Score = 41.2 bits (95), Expect = 0.011
Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 1599 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1656
I + R L +D G DPY+K IG K V + I L PV+ E C L L
Sbjct: 44 ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 99
Query: 1657 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1690
+ L I ++DYD +D+ +G +DL L++
Sbjct: 100 REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 133
Score = 40.8 bits (94), Expect = 0.014
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 5/91 (5%)
Query: 2 LRVFILYAENVHTPD-TDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
L+V ++ AE + D T SD +C + T + ++NP WN+ F +++K D
Sbjct: 407 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----D 462
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREV 91
S L V V D + FLG+ +PL +
Sbjct: 463 IHSVLEVTVYDEDRDRSADFLGKVAIPLLSI 493
Score = 38.9 bits (89), Expect = 0.053
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%)
Query: 1580 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1639
P R FH L G +++ ++RA GL D GK DP+ + + + Y
Sbjct: 394 PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 447
Query: 1640 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1683
L P + K+F + L++T+YD D + +G+ + L
Sbjct: 448 LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 490
Score = 37.7 bits (86), Expect = 0.12
Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Query: 448 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 506
DP+V+ GK + SKI+ K NP W + + + + E + I++ D+D +D +
Sbjct: 62 DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 119
Query: 507 ATTYLSMSKI 516
+ +L ++++
Sbjct: 120 GSAFLDLTQL 129
Score = 35.0 bits (79), Expect = 0.77
Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Query: 19 ISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRN 78
+SD Y K ++K++ ++NP W E F++ L ++G + + D + R+
Sbjct: 269 LSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGVIDITAWDKDAGKRD 325
Query: 79 RFLGEAKVPL 88
F+G +V L
Sbjct: 326 DFIGRCQVDL 335
Score = 35.0 bits (79), Expect = 0.77
Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%)
Query: 1171 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1230
L+ + +A L A D SDP+ +V + T V LNP W++ F
Sbjct: 407 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 458
Query: 1231 PATVAEQPPSIVVELYDHDTYGADEFMGR 1259
+ + + V +YD D + +F+G+
Sbjct: 459 --NIKDIHSVLEVTVYDEDRDRSADFLGK 485
Score = 34.3 bits (77), Expect = 1.3
Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%)
Query: 1169 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1225
Y L + + + LAA D+ SDPY V F + ++ ++ LNP W++ +
Sbjct: 40 YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 96
Query: 1226 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1258
+ EP + ++++D+D D+FMG
Sbjct: 97 DHLREP---------LYIKVFDYDFGLQDDFMG 120
Score = 32.0 bits (71), Expect = 6.5
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 442 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 501
+ L DP+V+ + SKI+ KT NPQW + ++ + I D D
Sbjct: 265 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 323
Query: 502 HNDIVATTYLSMSKIS 517
+D + + +S +S
Sbjct: 324 RDDFIGRCQVDLSALS 339
>gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo
sapiens]
Length = 999
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)
Query: 1175 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1234
+ + RDL AMD + SDPY HQ K+ ++ TLNP W + F+ E
Sbjct: 476 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 527
Query: 1235 AEQPPSIVVELYDHDTYGADEFMGRC 1260
E+ I + +D D D+F+GRC
Sbjct: 528 -ERGGVIDITAWDKDAGKRDDFIGRC 552
Score = 42.7 bits (99), Expect = 0.004
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 1596 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1655
+V I ++ L+ D NG DPY+K +G + + +P TL P + + F+
Sbjct: 471 IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 528
Query: 1656 LEKDLKITLYDYDLLSKDEKIGETVVDL 1683
+ IT +D D +D+ IG VDL
Sbjct: 529 RGGVIDITAWDKDAGKRDDFIGRCQVDL 556
Score = 41.2 bits (95), Expect = 0.011
Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 1599 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1656
I + R L +D G DPY+K IG K V + I L PV+ E C L L
Sbjct: 265 ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 320
Query: 1657 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1690
+ L I ++DYD +D+ +G +DL L++
Sbjct: 321 REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 354
Score = 40.8 bits (94), Expect = 0.014
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 5/91 (5%)
Query: 2 LRVFILYAENVHTPD-TDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
L+V ++ AE + D T SD +C + T + ++NP WN+ F +++K D
Sbjct: 628 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----D 683
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREV 91
S L V V D + FLG+ +PL +
Sbjct: 684 IHSVLEVTVYDEDRDRSADFLGKVAIPLLSI 714
Score = 38.9 bits (89), Expect = 0.053
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%)
Query: 1580 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1639
P R FH L G +++ ++RA GL D GK DP+ + + + Y
Sbjct: 615 PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 668
Query: 1640 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1683
L P + K+F + L++T+YD D + +G+ + L
Sbjct: 669 LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 711
Score = 37.7 bits (86), Expect = 0.12
Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Query: 448 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 506
DP+V+ GK + SKI+ K NP W + + + + E + I++ D+D +D +
Sbjct: 283 DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 340
Query: 507 ATTYLSMSKI 516
+ +L ++++
Sbjct: 341 GSAFLDLTQL 350
Score = 35.0 bits (79), Expect = 0.77
Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Query: 19 ISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRN 78
+SD Y K ++K++ ++NP W E F++ L ++G + + D + R+
Sbjct: 490 LSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGVIDITAWDKDAGKRD 546
Query: 79 RFLGEAKVPL 88
F+G +V L
Sbjct: 547 DFIGRCQVDL 556
Score = 35.0 bits (79), Expect = 0.77
Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%)
Query: 1171 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1230
L+ + +A L A D SDP+ +V + T V LNP W++ F
Sbjct: 628 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 679
Query: 1231 PATVAEQPPSIVVELYDHDTYGADEFMGR 1259
+ + + V +YD D + +F+G+
Sbjct: 680 --NIKDIHSVLEVTVYDEDRDRSADFLGK 706
Score = 34.3 bits (77), Expect = 1.3
Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%)
Query: 1169 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1225
Y L + + + LAA D+ SDPY V F + ++ ++ LNP W++ +
Sbjct: 261 YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 317
Query: 1226 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1258
+ EP + ++++D+D D+FMG
Sbjct: 318 DHLREP---------LYIKVFDYDFGLQDDFMG 341
Score = 32.0 bits (71), Expect = 6.5
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 442 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 501
+ L DP+V+ + SKI+ KT NPQW + ++ + I D D
Sbjct: 486 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 544
Query: 502 HNDIVATTYLSMSKIS 517
+D + + +S +S
Sbjct: 545 RDDFIGRCQVDLSALS 560
>gi|239743309 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 2 [Homo sapiens]
Length = 731
Score = 53.1 bits (126), Expect = 3e-06
Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 11/109 (10%)
Query: 1171 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1230
LRC + +ARDLA D++ SDP+ V + ++++T +VK + P W++T +E E+ E
Sbjct: 63 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET---FEFEL-QE 118
Query: 1231 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRL--AWFPL 1277
A A + VE +D D ++F+G+ + R+ + WF L
Sbjct: 119 GAMEA-----LCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRL 162
Score = 48.5 bits (114), Expect = 7e-05
Identities = 24/94 (25%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Query: 1591 GPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFEL 1650
G + C +R ++ A L PKD NG DP++++ K + + + + + P + + FE
Sbjct: 57 GARACRLRCSVLEARDLAPKDRNGTSDPFVRVRY--KGRTRETSIVKKSCYPRWNETFEF 114
Query: 1651 TCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLE 1684
+ L + +D+DL+S+++ +G+ V+D++
Sbjct: 115 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQ 148
Score = 42.4 bits (98), Expect = 0.005
Identities = 31/136 (22%), Positives = 53/136 (38%), Gaps = 18/136 (13%)
Query: 381 APLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFE 440
A L DP E+ + E +L R V A DL D
Sbjct: 33 AHLTEVDPDEEVQG-EIHLRLEVWPGARACRLRCSVLEARDLAPKD-------------- 77
Query: 441 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRL 500
+ DPFV V + G+ + I++K+ P+WN+ +M E + + DWD +
Sbjct: 78 --RNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAM-EALCVEAWDWDLV 134
Query: 501 THNDIVATTYLSMSKI 516
+ ND + + + ++
Sbjct: 135 SRNDFLGKVVIDVQRL 150
Score = 41.6 bits (96), Expect = 0.008
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 4/91 (4%)
Query: 2 LRVFILYAENVHTPDTD-ISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
LR +L A ++ D + SD + + G + T ++K S P WNE FE++L+ ++
Sbjct: 63 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAME 122
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREV 91
L V D + + RN FLG+ + ++ +
Sbjct: 123 ---ALCVEAWDWDLVSRNDFLGKVVIDVQRL 150
>gi|239743307 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 1 [Homo sapiens]
Length = 757
Score = 53.1 bits (126), Expect = 3e-06
Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 11/109 (10%)
Query: 1171 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1230
LRC + +ARDLA D++ SDP+ V + ++++T +VK + P W++T +E E+ E
Sbjct: 135 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET---FEFEL-QE 190
Query: 1231 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRL--AWFPL 1277
A A + VE +D D ++F+G+ + R+ + WF L
Sbjct: 191 GAMEA-----LCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRL 234
Score = 48.5 bits (114), Expect = 7e-05
Identities = 24/94 (25%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Query: 1591 GPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFEL 1650
G + C +R ++ A L PKD NG DP++++ K + + + + + P + + FE
Sbjct: 129 GARACRLRCSVLEARDLAPKDRNGTSDPFVRVRY--KGRTRETSIVKKSCYPRWNETFEF 186
Query: 1651 TCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLE 1684
+ L + +D+DL+S+++ +G+ V+D++
Sbjct: 187 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQ 220
Score = 43.1 bits (100), Expect = 0.003
Identities = 53/268 (19%), Positives = 96/268 (35%), Gaps = 60/268 (22%)
Query: 255 VQVIEGRQLPGVNIKP------VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGEL 308
++++EG+ LP +I +VKV + + K P + E +L +
Sbjct: 9 IRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPT---- 64
Query: 309 FDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYL 368
+ V+D +L D ++G+ + TI P+ G G+
Sbjct: 65 -FHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPK------------------GFSGW- 104
Query: 369 KTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDA 428
A L DP E+ + E +L R V A DL D
Sbjct: 105 ------------AHLTEVDPDEEVQG-EIHLRLEVWPGARACRLRCSVLEARDLAPKD-- 149
Query: 429 VMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCE 488
+ DPFV V + G+ + I++K+ P+WN+ +M E
Sbjct: 150 --------------RNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAM-E 194
Query: 489 KMRIRIIDWDRLTHNDIVATTYLSMSKI 516
+ + DWD ++ ND + + + ++
Sbjct: 195 ALCVEAWDWDLVSRNDFLGKVVIDVQRL 222
Score = 41.6 bits (96), Expect = 0.008
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 4/91 (4%)
Query: 2 LRVFILYAENVHTPDTD-ISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
LR +L A ++ D + SD + + G + T ++K S P WNE FE++L+ ++
Sbjct: 135 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAME 194
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREV 91
L V D + + RN FLG+ + ++ +
Sbjct: 195 ---ALCVEAWDWDLVSRNDFLGKVVIDVQRL 222
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,072,818
Number of Sequences: 37866
Number of extensions: 4673079
Number of successful extensions: 16618
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 143
Number of HSP's that attempted gapping in prelim test: 14836
Number of HSP's gapped (non-prelim): 1186
length of query: 2097
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1979
effective length of database: 13,779,330
effective search space: 27269294070
effective search space used: 27269294070
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.