Guide to the Human Genome
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Search of human proteins with 195976756

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|195976756 dysferlin isoform 10 [Homo sapiens]
         (2087 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|195976756 dysferlin isoform 10 [Homo sapiens]                     4299   0.0  
gi|195976758 dysferlin isoform 11 [Homo sapiens]                     4288   0.0  
gi|195976764 dysferlin isoform 14 [Homo sapiens]                     4283   0.0  
gi|195976773 dysferlin isoform 5 [Homo sapiens]                      4249   0.0  
gi|195976754 dysferlin isoform 9 [Homo sapiens]                      4245   0.0  
gi|195976769 dysferlin isoform 6 [Homo sapiens]                      4238   0.0  
gi|4503431 dysferlin isoform 8 [Homo sapiens]                        4234   0.0  
gi|195976779 dysferlin isoform 1 [Homo sapiens]                      4232   0.0  
gi|195976762 dysferlin isoform 13 [Homo sapiens]                     4229   0.0  
gi|195976760 dysferlin isoform 12 [Homo sapiens]                     4218   0.0  
gi|195976777 dysferlin isoform 3 [Homo sapiens]                      4195   0.0  
gi|195976821 dysferlin isoform 2 [Homo sapiens]                      4184   0.0  
gi|195976775 dysferlin isoform 4 [Homo sapiens]                      4179   0.0  
gi|195976766 dysferlin isoform 7 [Homo sapiens]                      4168   0.0  
gi|19718759 myoferlin isoform b [Homo sapiens]                       2380   0.0  
gi|7305053 myoferlin isoform a [Homo sapiens]                        2372   0.0  
gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens]                   1432   0.0  
gi|35493868 otoferlin isoform b [Homo sapiens]                        726   0.0  
gi|35493853 otoferlin isoform c [Homo sapiens]                        723   0.0  
gi|34740331 otoferlin isoform a [Homo sapiens]                        723   0.0  
gi|119120884 fer-1-like 6 [Homo sapiens]                              720   0.0  
gi|35493860 otoferlin isoform d [Homo sapiens]                        719   0.0  
gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens]                    711   0.0  
gi|4759026 RAS protein activator like 1 [Homo sapiens]                 65   5e-10
gi|150170670 piccolo isoform 2 [Homo sapiens]                          54   1e-06
gi|150378539 piccolo isoform 1 [Homo sapiens]                          54   1e-06
gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo...    54   2e-06
gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom...    54   2e-06
gi|239743309 PREDICTED: similar to calcium-promoted Ras inactiva...    53   3e-06
gi|239743307 PREDICTED: similar to calcium-promoted Ras inactiva...    53   3e-06

>gi|195976756 dysferlin isoform 10 [Homo sapiens]
          Length = 2087

 Score = 4299 bits (11150), Expect = 0.0
 Identities = 2087/2087 (100%), Positives = 2087/2087 (100%)

Query: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
            MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
            QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120

Query: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180
            VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP
Sbjct: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180

Query: 181  GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240
            GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV
Sbjct: 181  GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240

Query: 241  VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300
            VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE
Sbjct: 241  VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300

Query: 301  FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360
            FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED
Sbjct: 301  FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360

Query: 361  KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420
            KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV
Sbjct: 361  KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420

Query: 421  EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480
            EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL
Sbjct: 421  EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480

Query: 481  SMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRG 540
            SMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRG
Sbjct: 481  SMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRG 540

Query: 541  RLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFE 600
            RLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFE
Sbjct: 541  RLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFE 600

Query: 601  VSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIET 660
            VSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIET
Sbjct: 601  VSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIET 660

Query: 661  QNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSAT 720
            QNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSAT
Sbjct: 661  QNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSAT 720

Query: 721  HLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIV 780
            HLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIV
Sbjct: 721  HLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIV 780

Query: 781  IWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRV 840
            IWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRV
Sbjct: 781  IWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRV 840

Query: 841  KLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLP 900
            KLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLP
Sbjct: 841  KLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLP 900

Query: 901  KDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTD 960
            KDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTD
Sbjct: 901  KDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTD 960

Query: 961  VNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMY 1020
            VNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMY
Sbjct: 961  VNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMY 1020

Query: 1021 YTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRW 1080
            YTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRW
Sbjct: 1021 YTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRW 1080

Query: 1081 RRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHL 1140
            RRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHL
Sbjct: 1081 RRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHL 1140

Query: 1141 RCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEP 1200
            RCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEP
Sbjct: 1141 RCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEP 1200

Query: 1201 ATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASF 1260
            ATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASF
Sbjct: 1201 ATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASF 1260

Query: 1261 ELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAI 1320
            ELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAI
Sbjct: 1261 ELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAI 1320

Query: 1321 EILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPRE 1380
            EILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPRE
Sbjct: 1321 EILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPRE 1380

Query: 1381 ELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGE 1440
            ELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGE
Sbjct: 1381 ELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGE 1440

Query: 1441 DVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGS 1500
            DVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGS
Sbjct: 1441 DVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGS 1500

Query: 1501 YLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYP 1560
            YLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYP
Sbjct: 1501 YLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYP 1560

Query: 1561 LPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVS 1620
            LPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVS
Sbjct: 1561 LPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVS 1620

Query: 1621 DQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1680
            DQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK
Sbjct: 1621 DQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1680

Query: 1681 FGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEI 1740
            FGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEI
Sbjct: 1681 FGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEI 1740

Query: 1741 EAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKA 1800
            EAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKA
Sbjct: 1741 EAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKA 1800

Query: 1801 LGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQK 1860
            LGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQK
Sbjct: 1801 LGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQK 1860

Query: 1861 TDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDN 1920
            TDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDN
Sbjct: 1861 TDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDN 1920

Query: 1921 DKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA 1980
            DKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA
Sbjct: 1921 DKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA 1980

Query: 1981 EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYK 2040
            EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYK
Sbjct: 1981 EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYK 2040

Query: 2041 TMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2087
            TMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2041 TMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2087


>gi|195976758 dysferlin isoform 11 [Homo sapiens]
          Length = 2101

 Score = 4288 bits (11122), Expect = 0.0
 Identities = 2086/2101 (99%), Positives = 2087/2101 (99%), Gaps = 14/2101 (0%)

Query: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
            MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
            QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120

Query: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180
            VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP
Sbjct: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180

Query: 181  GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240
            GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV
Sbjct: 181  GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240

Query: 241  VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300
            VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE
Sbjct: 241  VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300

Query: 301  FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360
            FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED
Sbjct: 301  FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360

Query: 361  KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420
            KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV
Sbjct: 361  KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420

Query: 421  EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480
            EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL
Sbjct: 421  EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480

Query: 481  SMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT 526
            SMSKISAPGGEIE              +DDYLGFLPTFGPCYINLYGSPREFTGFPDPYT
Sbjct: 481  SMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT 540

Query: 527  ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS 586
            ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS
Sbjct: 541  ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS 600

Query: 587  ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV 646
            ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV
Sbjct: 601  ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV 660

Query: 647  LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC 706
            LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC
Sbjct: 661  LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC 720

Query: 707  SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 766
            SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR
Sbjct: 721  SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 780

Query: 767  ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 826
            ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM
Sbjct: 781  ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 840

Query: 827  EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 886
            EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT
Sbjct: 841  EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 900

Query: 887  YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL 946
            YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL
Sbjct: 901  YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL 960

Query: 947  PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP 1006
            PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP
Sbjct: 961  PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP 1020

Query: 1007 ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH 1066
            ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH
Sbjct: 1021 ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH 1080

Query: 1067 LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP 1126
            LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP
Sbjct: 1081 LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP 1140

Query: 1127 TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD 1186
            TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD
Sbjct: 1141 TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD 1200

Query: 1187 QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL 1246
            QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL
Sbjct: 1201 QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL 1260

Query: 1247 TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM 1306
            TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM
Sbjct: 1261 TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM 1320

Query: 1307 VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF 1366
            VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF
Sbjct: 1321 VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF 1380

Query: 1367 DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP 1426
            DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP
Sbjct: 1381 DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP 1440

Query: 1427 QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWS 1486
            QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWS
Sbjct: 1441 QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWS 1500

Query: 1487 KFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDP 1546
            KFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDP
Sbjct: 1501 KFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDP 1560

Query: 1547 SVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKC 1606
            SVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKC
Sbjct: 1561 SVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKC 1620

Query: 1607 DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI 1666
            DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI
Sbjct: 1621 DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI 1680

Query: 1667 GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD 1726
            GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD
Sbjct: 1681 GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD 1740

Query: 1727 RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE 1786
            RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE
Sbjct: 1741 RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE 1800

Query: 1787 QGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIY 1846
            QGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIY
Sbjct: 1801 QGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIY 1860

Query: 1847 VKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTE 1906
            VKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTE
Sbjct: 1861 VKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTE 1920

Query: 1907 SKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSL 1966
            SKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSL
Sbjct: 1921 SKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSL 1980

Query: 1967 FEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2026
            FEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR
Sbjct: 1981 FEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2040

Query: 2027 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPF 2086
            RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPF
Sbjct: 2041 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPF 2100

Query: 2087 S 2087
            S
Sbjct: 2101 S 2101


>gi|195976764 dysferlin isoform 14 [Homo sapiens]
          Length = 2118

 Score = 4283 bits (11108), Expect = 0.0
 Identities = 2087/2118 (98%), Positives = 2087/2118 (98%), Gaps = 31/2118 (1%)

Query: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
            MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
            QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120

Query: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA---------------------------- 152
            VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                            
Sbjct: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180

Query: 153  ---DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 209
               DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS
Sbjct: 181  APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240

Query: 210  RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 269
            RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN
Sbjct: 241  RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300

Query: 270  LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 329
            LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF
Sbjct: 301  LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360

Query: 330  SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 389
            SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE
Sbjct: 361  SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420

Query: 390  DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 449
            DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP
Sbjct: 421  DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480

Query: 450  AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI 509
            AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI
Sbjct: 481  AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI 540

Query: 510  NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV 569
            NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV
Sbjct: 541  NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV 600

Query: 570  EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD 629
            EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD
Sbjct: 601  EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD 660

Query: 630  GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE 689
            GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE
Sbjct: 661  GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE 720

Query: 690  DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS 749
            DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS
Sbjct: 721  DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS 780

Query: 750  ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY 809
            ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY
Sbjct: 781  ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY 840

Query: 810  CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE 869
            CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE
Sbjct: 841  CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE 900

Query: 870  NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD 929
            NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD
Sbjct: 901  NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD 960

Query: 930  AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL 989
            AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL
Sbjct: 961  AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL 1020

Query: 990  NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE 1049
            NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE
Sbjct: 1021 NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE 1080

Query: 1050 AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK 1109
            AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK
Sbjct: 1081 AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK 1140

Query: 1110 SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH 1169
            SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH
Sbjct: 1141 SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH 1200

Query: 1170 QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1229
            QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC
Sbjct: 1201 QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1260

Query: 1230 ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1289
            ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE
Sbjct: 1261 ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1320

Query: 1290 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1349
            DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG
Sbjct: 1321 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1380

Query: 1350 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1409
            QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR
Sbjct: 1381 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1440

Query: 1410 SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNT 1469
            SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNT
Sbjct: 1441 SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNT 1500

Query: 1470 ASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFC 1529
            ASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFC
Sbjct: 1501 ASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFC 1560

Query: 1530 NTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRI 1589
            NTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRI
Sbjct: 1561 NTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRI 1620

Query: 1590 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1649
            YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD
Sbjct: 1621 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1680

Query: 1650 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1709
            LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL
Sbjct: 1681 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1740

Query: 1710 HLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVP 1769
            HLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVP
Sbjct: 1741 HLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVP 1800

Query: 1770 EHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRD 1829
            EHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRD
Sbjct: 1801 EHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRD 1860

Query: 1830 VILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQ 1889
            VILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQ
Sbjct: 1861 VILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQ 1920

Query: 1890 VCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKC 1949
            VCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKC
Sbjct: 1921 VCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKC 1980

Query: 1950 SLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPA 2009
            SLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPA
Sbjct: 1981 SLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPA 2040

Query: 2010 GQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAI 2069
            GQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAI
Sbjct: 2041 GQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAI 2100

Query: 2070 FIYAFPNYAAMKLVKPFS 2087
            FIYAFPNYAAMKLVKPFS
Sbjct: 2101 FIYAFPNYAAMKLVKPFS 2118


>gi|195976773 dysferlin isoform 5 [Homo sapiens]
          Length = 2088

 Score = 4249 bits (11019), Expect = 0.0
 Identities = 2067/2088 (98%), Positives = 2071/2088 (99%), Gaps = 1/2088 (0%)

Query: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180

Query: 180  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
            PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 181  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240

Query: 240  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
            VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 241  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300

Query: 300  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
            EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 301  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360

Query: 360  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
            DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 361  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420

Query: 420  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
            VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 421  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480

Query: 480  LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR 539
            LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR
Sbjct: 481  LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR 540

Query: 540  GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF 599
            GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF
Sbjct: 541  GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF 600

Query: 600  EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE 659
            EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE
Sbjct: 601  EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE 660

Query: 660  TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA 719
            TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA
Sbjct: 661  TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA 720

Query: 720  THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI 779
            THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI
Sbjct: 721  THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI 780

Query: 780  VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR 839
            VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR
Sbjct: 781  VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR 840

Query: 840  VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL 899
            VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL
Sbjct: 841  VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL 900

Query: 900  PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT 959
            PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT
Sbjct: 901  PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT 960

Query: 960  DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM 1019
            DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM
Sbjct: 961  DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM 1020

Query: 1020 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR 1079
            YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR
Sbjct: 1021 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR 1080

Query: 1080 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH 1139
            WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH
Sbjct: 1081 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH 1140

Query: 1140 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1199
            LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE
Sbjct: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1200

Query: 1200 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS 1259
            PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS
Sbjct: 1201 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS 1260

Query: 1260 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA 1319
            FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA
Sbjct: 1261 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA 1320

Query: 1320 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR 1379
            IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR
Sbjct: 1321 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR 1380

Query: 1380 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG 1439
            EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG
Sbjct: 1381 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG 1440

Query: 1440 EDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCG 1499
            EDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCG
Sbjct: 1441 EDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCG 1500

Query: 1500 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY 1559
            SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY
Sbjct: 1501 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY 1560

Query: 1560 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV 1619
            PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV
Sbjct: 1561 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV 1620

Query: 1620 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS 1679
            SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS
Sbjct: 1621 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS 1680

Query: 1680 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE 1739
            KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE
Sbjct: 1681 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE 1740

Query: 1740 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK 1799
            IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK
Sbjct: 1741 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK 1800

Query: 1800 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1859
            ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ
Sbjct: 1801 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1860

Query: 1860 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1919
            KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD
Sbjct: 1861 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1920

Query: 1920 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV 1979
            NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV
Sbjct: 1921 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV 1980

Query: 1980 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY 2039
            AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY
Sbjct: 1981 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY 2040

Query: 2040 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2087
            KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2041 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2088


>gi|195976754 dysferlin isoform 9 [Homo sapiens]
          Length = 2066

 Score = 4245 bits (11010), Expect = 0.0
 Identities = 2066/2087 (98%), Positives = 2066/2087 (98%), Gaps = 21/2087 (1%)

Query: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
            MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
            QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120

Query: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180
            VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP
Sbjct: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180

Query: 181  GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240
            GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV
Sbjct: 181  GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240

Query: 241  VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300
            VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE
Sbjct: 241  VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300

Query: 301  FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360
            FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED
Sbjct: 301  FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360

Query: 361  KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420
            KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV
Sbjct: 361  KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420

Query: 421  EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480
            EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL
Sbjct: 421  EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480

Query: 481  SMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRG 540
            SMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRG
Sbjct: 481  SMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRG 540

Query: 541  RLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFE 600
            RLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFE
Sbjct: 541  RLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFE 600

Query: 601  VSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIET 660
            VSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIET
Sbjct: 601  VSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIET 660

Query: 661  QNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSAT 720
            QNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSAT
Sbjct: 661  QNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSAT 720

Query: 721  HLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIV 780
            HLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIV
Sbjct: 721  HLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIV 780

Query: 781  IWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRV 840
            IWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRV
Sbjct: 781  IWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRV 840

Query: 841  KLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLP 900
            KLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLP
Sbjct: 841  KLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLP 900

Query: 901  KDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTD 960
            KDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTD
Sbjct: 901  KDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTD 960

Query: 961  VNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMY 1020
            VNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMY
Sbjct: 961  VNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMY 1020

Query: 1021 YTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRW 1080
            YTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRW
Sbjct: 1021 YTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRW 1080

Query: 1081 RRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHL 1140
            RRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHL
Sbjct: 1081 RRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHL 1140

Query: 1141 RCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEP 1200
            RCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEP
Sbjct: 1141 RCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEP 1200

Query: 1201 ATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASF 1260
            ATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASF
Sbjct: 1201 ATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASF 1260

Query: 1261 ELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAI 1320
            ELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAI
Sbjct: 1261 ELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAI 1320

Query: 1321 EILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPRE 1380
            EILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPRE
Sbjct: 1321 EILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPRE 1380

Query: 1381 ELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGE 1440
            ELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGE
Sbjct: 1381 ELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGE 1440

Query: 1441 DVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGS 1500
            DVLIDIDDKEPLIPIQ                     EEEFIDWWSKFFASIGEREKCGS
Sbjct: 1441 DVLIDIDDKEPLIPIQ---------------------EEEFIDWWSKFFASIGEREKCGS 1479

Query: 1501 YLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYP 1560
            YLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYP
Sbjct: 1480 YLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYP 1539

Query: 1561 LPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVS 1620
            LPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVS
Sbjct: 1540 LPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVS 1599

Query: 1621 DQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1680
            DQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK
Sbjct: 1600 DQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1659

Query: 1681 FGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEI 1740
            FGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEI
Sbjct: 1660 FGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEI 1719

Query: 1741 EAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKA 1800
            EAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKA
Sbjct: 1720 EAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKA 1779

Query: 1801 LGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQK 1860
            LGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQK
Sbjct: 1780 LGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQK 1839

Query: 1861 TDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDN 1920
            TDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDN
Sbjct: 1840 TDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDN 1899

Query: 1921 DKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA 1980
            DKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA
Sbjct: 1900 DKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA 1959

Query: 1981 EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYK 2040
            EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYK
Sbjct: 1960 EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYK 2019

Query: 2041 TMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2087
            TMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2020 TMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2066


>gi|195976769 dysferlin isoform 6 [Homo sapiens]
          Length = 2102

 Score = 4238 bits (10991), Expect = 0.0
 Identities = 2066/2102 (98%), Positives = 2071/2102 (98%), Gaps = 15/2102 (0%)

Query: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180

Query: 180  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
            PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 181  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240

Query: 240  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
            VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 241  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300

Query: 300  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
            EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 301  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360

Query: 360  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
            DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 361  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420

Query: 420  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
            VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 421  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480

Query: 480  LSMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 525
            LSMSKISAPGGEIE              +DDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 481  LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540

Query: 526  TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 585
            TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 541  TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600

Query: 586  SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 645
            SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 601  SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660

Query: 646  VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 705
            VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 661  VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720

Query: 706  CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 765
            CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 721  CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780

Query: 766  RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 825
            RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 781  RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840

Query: 826  MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 885
            MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 841  MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900

Query: 886  TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 945
            TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 901  TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960

Query: 946  LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1005
            LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 961  LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020

Query: 1006 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1065
            PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080

Query: 1066 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1125
            HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140

Query: 1126 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1185
            PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200

Query: 1186 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1245
            DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260

Query: 1246 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1305
            LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320

Query: 1306 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1365
            MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380

Query: 1366 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1425
            FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440

Query: 1426 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1485
            PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW
Sbjct: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1500

Query: 1486 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1545
            SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED
Sbjct: 1501 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1560

Query: 1546 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1605
            PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK
Sbjct: 1561 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1620

Query: 1606 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1665
            CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK
Sbjct: 1621 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1680

Query: 1666 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1725
            IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT
Sbjct: 1681 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1740

Query: 1726 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1785
            DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI
Sbjct: 1741 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1800

Query: 1786 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1845
            EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI
Sbjct: 1801 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1860

Query: 1846 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1905
            YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT
Sbjct: 1861 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1920

Query: 1906 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1965
            ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS
Sbjct: 1921 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1980

Query: 1966 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2025
            LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP
Sbjct: 1981 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2040

Query: 2026 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2085
            RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP
Sbjct: 2041 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100

Query: 2086 FS 2087
            FS
Sbjct: 2101 FS 2102


>gi|4503431 dysferlin isoform 8 [Homo sapiens]
          Length = 2080

 Score = 4234 bits (10982), Expect = 0.0
 Identities = 2065/2101 (98%), Positives = 2066/2101 (98%), Gaps = 35/2101 (1%)

Query: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
            MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
            QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120

Query: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180
            VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP
Sbjct: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180

Query: 181  GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240
            GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV
Sbjct: 181  GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240

Query: 241  VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300
            VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE
Sbjct: 241  VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300

Query: 301  FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360
            FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED
Sbjct: 301  FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360

Query: 361  KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420
            KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV
Sbjct: 361  KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420

Query: 421  EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480
            EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL
Sbjct: 421  EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480

Query: 481  SMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT 526
            SMSKISAPGGEIE              +DDYLGFLPTFGPCYINLYGSPREFTGFPDPYT
Sbjct: 481  SMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT 540

Query: 527  ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS 586
            ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS
Sbjct: 541  ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS 600

Query: 587  ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV 646
            ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV
Sbjct: 601  ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV 660

Query: 647  LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC 706
            LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC
Sbjct: 661  LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC 720

Query: 707  SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 766
            SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR
Sbjct: 721  SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 780

Query: 767  ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 826
            ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM
Sbjct: 781  ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 840

Query: 827  EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 886
            EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT
Sbjct: 841  EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 900

Query: 887  YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL 946
            YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL
Sbjct: 901  YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL 960

Query: 947  PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP 1006
            PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP
Sbjct: 961  PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP 1020

Query: 1007 ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH 1066
            ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH
Sbjct: 1021 ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH 1080

Query: 1067 LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP 1126
            LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP
Sbjct: 1081 LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP 1140

Query: 1127 TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD 1186
            TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD
Sbjct: 1141 TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD 1200

Query: 1187 QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL 1246
            QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL
Sbjct: 1201 QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL 1260

Query: 1247 TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM 1306
            TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM
Sbjct: 1261 TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM 1320

Query: 1307 VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF 1366
            VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF
Sbjct: 1321 VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF 1380

Query: 1367 DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP 1426
            DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP
Sbjct: 1381 DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP 1440

Query: 1427 QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWS 1486
            QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ                     EEEFIDWWS
Sbjct: 1441 QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ---------------------EEEFIDWWS 1479

Query: 1487 KFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDP 1546
            KFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDP
Sbjct: 1480 KFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDP 1539

Query: 1547 SVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKC 1606
            SVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKC
Sbjct: 1540 SVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKC 1599

Query: 1607 DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI 1666
            DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI
Sbjct: 1600 DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI 1659

Query: 1667 GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD 1726
            GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD
Sbjct: 1660 GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD 1719

Query: 1727 RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE 1786
            RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE
Sbjct: 1720 RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE 1779

Query: 1787 QGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIY 1846
            QGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIY
Sbjct: 1780 QGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIY 1839

Query: 1847 VKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTE 1906
            VKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTE
Sbjct: 1840 VKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTE 1899

Query: 1907 SKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSL 1966
            SKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSL
Sbjct: 1900 SKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSL 1959

Query: 1967 FEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2026
            FEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR
Sbjct: 1960 FEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2019

Query: 2027 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPF 2086
            RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPF
Sbjct: 2020 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPF 2079

Query: 2087 S 2087
            S
Sbjct: 2080 S 2080


>gi|195976779 dysferlin isoform 1 [Homo sapiens]
          Length = 2119

 Score = 4232 bits (10977), Expect = 0.0
 Identities = 2067/2119 (97%), Positives = 2071/2119 (97%), Gaps = 32/2119 (1%)

Query: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                           
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180

Query: 153  ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208
                DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240

Query: 209  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300

Query: 269  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360

Query: 329  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420

Query: 389  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480

Query: 449  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 508
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540

Query: 509  INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 568
            INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 541  INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600

Query: 569  VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 628
            VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 601  VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660

Query: 629  DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 688
            DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 661  DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720

Query: 689  EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 748
            EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 721  EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780

Query: 749  SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 808
            SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 781  SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840

Query: 809  YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 868
            YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 841  YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900

Query: 869  ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 928
            ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 901  ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960

Query: 929  DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 988
            DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 961  DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020

Query: 989  LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1048
            LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080

Query: 1049 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1108
            EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140

Query: 1109 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1168
            KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200

Query: 1169 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1228
            HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260

Query: 1229 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1288
            CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320

Query: 1289 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1348
            EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380

Query: 1349 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1408
            GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440

Query: 1409 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1468
            RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN
Sbjct: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1500

Query: 1469 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1528
            TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF
Sbjct: 1501 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1560

Query: 1529 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1588
            CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR
Sbjct: 1561 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1620

Query: 1589 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1648
            IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK
Sbjct: 1621 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1680

Query: 1649 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1708
            DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL
Sbjct: 1681 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1740

Query: 1709 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1768
            LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV
Sbjct: 1741 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1800

Query: 1769 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1828
            PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR
Sbjct: 1801 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1860

Query: 1829 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1888
            DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE
Sbjct: 1861 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1920

Query: 1889 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1948
            QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK
Sbjct: 1921 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1980

Query: 1949 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2008
            CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP
Sbjct: 1981 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2040

Query: 2009 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2068
            AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA
Sbjct: 2041 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2100

Query: 2069 IFIYAFPNYAAMKLVKPFS 2087
            IFIYAFPNYAAMKLVKPFS
Sbjct: 2101 IFIYAFPNYAAMKLVKPFS 2119


>gi|195976762 dysferlin isoform 13 [Homo sapiens]
          Length = 2097

 Score = 4229 bits (10968), Expect = 0.0
 Identities = 2066/2118 (97%), Positives = 2066/2118 (97%), Gaps = 52/2118 (2%)

Query: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
            MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
            QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120

Query: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA---------------------------- 152
            VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                            
Sbjct: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180

Query: 153  ---DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 209
               DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS
Sbjct: 181  APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240

Query: 210  RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 269
            RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN
Sbjct: 241  RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300

Query: 270  LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 329
            LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF
Sbjct: 301  LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360

Query: 330  SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 389
            SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE
Sbjct: 361  SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420

Query: 390  DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 449
            DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP
Sbjct: 421  DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480

Query: 450  AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI 509
            AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI
Sbjct: 481  AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYI 540

Query: 510  NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV 569
            NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV
Sbjct: 541  NLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRV 600

Query: 570  EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD 629
            EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD
Sbjct: 601  EKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFD 660

Query: 630  GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE 689
            GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE
Sbjct: 661  GCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTE 720

Query: 690  DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS 749
            DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS
Sbjct: 721  DVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHS 780

Query: 750  ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY 809
            ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY
Sbjct: 781  ELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANY 840

Query: 810  CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE 869
            CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE
Sbjct: 841  CGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYE 900

Query: 870  NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD 929
            NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD
Sbjct: 901  NETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMD 960

Query: 930  AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL 989
            AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL
Sbjct: 961  AGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDL 1020

Query: 990  NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE 1049
            NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE
Sbjct: 1021 NRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAE 1080

Query: 1050 AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK 1109
            AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK
Sbjct: 1081 AEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDK 1140

Query: 1110 SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH 1169
            SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH
Sbjct: 1141 SEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLH 1200

Query: 1170 QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1229
            QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC
Sbjct: 1201 QSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRC 1260

Query: 1230 ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1289
            ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE
Sbjct: 1261 ICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1320

Query: 1290 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1349
            DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG
Sbjct: 1321 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1380

Query: 1350 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1409
            QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR
Sbjct: 1381 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1440

Query: 1410 SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNT 1469
            SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ             
Sbjct: 1441 SLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ------------- 1487

Query: 1470 ASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFC 1529
                    EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFC
Sbjct: 1488 --------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFC 1539

Query: 1530 NTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRI 1589
            NTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRI
Sbjct: 1540 NTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRI 1599

Query: 1590 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1649
            YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD
Sbjct: 1600 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1659

Query: 1650 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1709
            LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL
Sbjct: 1660 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1719

Query: 1710 HLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVP 1769
            HLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVP
Sbjct: 1720 HLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVP 1779

Query: 1770 EHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRD 1829
            EHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRD
Sbjct: 1780 EHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRD 1839

Query: 1830 VILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQ 1889
            VILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQ
Sbjct: 1840 VILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQ 1899

Query: 1890 VCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKC 1949
            VCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKC
Sbjct: 1900 VCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKC 1959

Query: 1950 SLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPA 2009
            SLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPA
Sbjct: 1960 SLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPA 2019

Query: 2010 GQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAI 2069
            GQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAI
Sbjct: 2020 GQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAI 2079

Query: 2070 FIYAFPNYAAMKLVKPFS 2087
            FIYAFPNYAAMKLVKPFS
Sbjct: 2080 FIYAFPNYAAMKLVKPFS 2097


>gi|195976760 dysferlin isoform 12 [Homo sapiens]
          Length = 2111

 Score = 4218 bits (10940), Expect = 0.0
 Identities = 2065/2132 (96%), Positives = 2066/2132 (96%), Gaps = 66/2132 (3%)

Query: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
            MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
            QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120

Query: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA---------------------------- 152
            VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                            
Sbjct: 121  VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180

Query: 153  ---DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 209
               DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS
Sbjct: 181  APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240

Query: 210  RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 269
            RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN
Sbjct: 241  RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300

Query: 270  LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 329
            LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF
Sbjct: 301  LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360

Query: 330  SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 389
            SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE
Sbjct: 361  SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420

Query: 390  DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 449
            DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP
Sbjct: 421  DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480

Query: 450  AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------VD 495
            AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE              +D
Sbjct: 481  AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLD 540

Query: 496  DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 555
            DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE
Sbjct: 541  DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 600

Query: 556  QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 615
            QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL
Sbjct: 601  QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 660

Query: 616  PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 675
            PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL
Sbjct: 661  PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 720

Query: 676  EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 735
            EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS
Sbjct: 721  EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 780

Query: 736  QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 795
            QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV
Sbjct: 781  QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 840

Query: 796  PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 855
            PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ
Sbjct: 841  PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 900

Query: 856  FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 915
            FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD
Sbjct: 901  FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 960

Query: 916  WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 975
            WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP
Sbjct: 961  WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 1020

Query: 976  LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1035
            LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD
Sbjct: 1021 LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1080

Query: 1036 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1095
            LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV
Sbjct: 1081 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1140

Query: 1096 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1155
            FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK
Sbjct: 1141 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1200

Query: 1156 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1215
            DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY
Sbjct: 1201 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1260

Query: 1216 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1275
            DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG
Sbjct: 1261 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1320

Query: 1276 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1335
            FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL
Sbjct: 1321 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1380

Query: 1336 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1395
            ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR
Sbjct: 1381 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1440

Query: 1396 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1455
            QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI
Sbjct: 1441 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1500

Query: 1456 QLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQ 1515
            Q                     EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQ
Sbjct: 1501 Q---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQ 1539

Query: 1516 LENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFH 1575
            LENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFH
Sbjct: 1540 LENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFH 1599

Query: 1576 QLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFG 1635
            QLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFG
Sbjct: 1600 QLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFG 1659

Query: 1636 KMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSG 1695
            KMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSG
Sbjct: 1660 KMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSG 1719

Query: 1696 PNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEE 1755
            PNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEE
Sbjct: 1720 PNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEE 1779

Query: 1756 RLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRA 1815
            RLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRA
Sbjct: 1780 RLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRA 1839

Query: 1816 RRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFN 1875
            RRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFN
Sbjct: 1840 RRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFN 1899

Query: 1876 WRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLD 1935
            WRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLD
Sbjct: 1900 WRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLD 1959

Query: 1936 LNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMT 1995
            LNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMT
Sbjct: 1960 LNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMT 2019

Query: 1996 LEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAII 2055
            LEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAII
Sbjct: 2020 LEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAII 2079

Query: 2056 LFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2087
            LFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2080 LFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2111


>gi|195976777 dysferlin isoform 3 [Homo sapiens]
          Length = 2067

 Score = 4195 bits (10879), Expect = 0.0
 Identities = 2046/2088 (97%), Positives = 2050/2088 (98%), Gaps = 22/2088 (1%)

Query: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180

Query: 180  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
            PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 181  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240

Query: 240  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
            VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 241  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300

Query: 300  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
            EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 301  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360

Query: 360  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
            DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 361  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420

Query: 420  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
            VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 421  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480

Query: 480  LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR 539
            LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR
Sbjct: 481  LSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYR 540

Query: 540  GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF 599
            GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF
Sbjct: 541  GRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQF 600

Query: 600  EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE 659
            EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE
Sbjct: 601  EVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIE 660

Query: 660  TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA 719
            TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA
Sbjct: 661  TQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSA 720

Query: 720  THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI 779
            THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI
Sbjct: 721  THLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDI 780

Query: 780  VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR 839
            VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR
Sbjct: 781  VIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIR 840

Query: 840  VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL 899
            VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL
Sbjct: 841  VKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKL 900

Query: 900  PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT 959
            PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT
Sbjct: 901  PKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYT 960

Query: 960  DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM 1019
            DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM
Sbjct: 961  DVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKM 1020

Query: 1020 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR 1079
            YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR
Sbjct: 1021 YYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRR 1080

Query: 1080 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH 1139
            WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH
Sbjct: 1081 WRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYH 1140

Query: 1140 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1199
            LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE
Sbjct: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1200

Query: 1200 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS 1259
            PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS
Sbjct: 1201 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLAS 1260

Query: 1260 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA 1319
            FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA
Sbjct: 1261 FELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTA 1320

Query: 1320 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR 1379
            IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR
Sbjct: 1321 IEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPR 1380

Query: 1380 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG 1439
            EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG
Sbjct: 1381 EELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG 1440

Query: 1440 EDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCG 1499
            EDVLIDIDDKEPLIPIQ                     EEEFIDWWSKFFASIGEREKCG
Sbjct: 1441 EDVLIDIDDKEPLIPIQ---------------------EEEFIDWWSKFFASIGEREKCG 1479

Query: 1500 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY 1559
            SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY
Sbjct: 1480 SYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIY 1539

Query: 1560 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV 1619
            PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV
Sbjct: 1540 PLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSV 1599

Query: 1620 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS 1679
            SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS
Sbjct: 1600 SDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLS 1659

Query: 1680 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE 1739
            KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE
Sbjct: 1660 KFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEE 1719

Query: 1740 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK 1799
            IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK
Sbjct: 1720 IEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPK 1779

Query: 1800 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1859
            ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ
Sbjct: 1780 ALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1839

Query: 1860 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1919
            KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD
Sbjct: 1840 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1899

Query: 1920 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV 1979
            NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV
Sbjct: 1900 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCV 1959

Query: 1980 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY 2039
            AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY
Sbjct: 1960 AEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPY 2019

Query: 2040 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2087
            KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2020 KTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2067


>gi|195976821 dysferlin isoform 2 [Homo sapiens]
          Length = 2081

 Score = 4184 bits (10851), Expect = 0.0
 Identities = 2045/2102 (97%), Positives = 2050/2102 (97%), Gaps = 36/2102 (1%)

Query: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180

Query: 180  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
            PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 181  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240

Query: 240  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
            VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 241  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300

Query: 300  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
            EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 301  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360

Query: 360  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
            DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 361  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420

Query: 420  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
            VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 421  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480

Query: 480  LSMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 525
            LSMSKISAPGGEIE              +DDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 481  LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540

Query: 526  TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 585
            TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 541  TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600

Query: 586  SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 645
            SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 601  SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660

Query: 646  VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 705
            VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 661  VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720

Query: 706  CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 765
            CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 721  CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780

Query: 766  RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 825
            RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 781  RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840

Query: 826  MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 885
            MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 841  MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900

Query: 886  TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 945
            TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 901  TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960

Query: 946  LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1005
            LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 961  LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020

Query: 1006 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1065
            PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080

Query: 1066 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1125
            HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140

Query: 1126 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1185
            PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200

Query: 1186 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1245
            DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260

Query: 1246 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1305
            LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320

Query: 1306 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1365
            MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380

Query: 1366 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1425
            FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440

Query: 1426 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1485
            PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ                     EEEFIDWW
Sbjct: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ---------------------EEEFIDWW 1479

Query: 1486 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1545
            SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED
Sbjct: 1480 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1539

Query: 1546 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1605
            PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK
Sbjct: 1540 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1599

Query: 1606 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1665
            CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK
Sbjct: 1600 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1659

Query: 1666 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1725
            IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT
Sbjct: 1660 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1719

Query: 1726 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1785
            DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI
Sbjct: 1720 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1779

Query: 1786 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1845
            EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI
Sbjct: 1780 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1839

Query: 1846 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1905
            YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT
Sbjct: 1840 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1899

Query: 1906 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1965
            ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS
Sbjct: 1900 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1959

Query: 1966 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2025
            LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP
Sbjct: 1960 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2019

Query: 2026 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2085
            RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP
Sbjct: 2020 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2079

Query: 2086 FS 2087
            FS
Sbjct: 2080 FS 2081


>gi|195976775 dysferlin isoform 4 [Homo sapiens]
          Length = 2098

 Score = 4179 bits (10837), Expect = 0.0
 Identities = 2046/2119 (96%), Positives = 2050/2119 (96%), Gaps = 53/2119 (2%)

Query: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                           
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180

Query: 153  ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208
                DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240

Query: 209  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300

Query: 269  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360

Query: 329  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420

Query: 389  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480

Query: 449  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 508
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY
Sbjct: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCY 540

Query: 509  INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 568
            INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR
Sbjct: 541  INLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILR 600

Query: 569  VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 628
            VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF
Sbjct: 601  VEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVF 660

Query: 629  DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 688
            DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST
Sbjct: 661  DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCST 720

Query: 689  EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 748
            EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH
Sbjct: 721  EDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGH 780

Query: 749  SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 808
            SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN
Sbjct: 781  SELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGAN 840

Query: 809  YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 868
            YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY
Sbjct: 841  YCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETY 900

Query: 869  ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 928
            ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM
Sbjct: 901  ENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDM 960

Query: 929  DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 988
            DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD
Sbjct: 961  DAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTD 1020

Query: 989  LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1048
            LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA
Sbjct: 1021 LNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQA 1080

Query: 1049 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1108
            EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD
Sbjct: 1081 EAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDD 1140

Query: 1109 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1168
            KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL
Sbjct: 1141 KSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFL 1200

Query: 1169 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1228
            HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR
Sbjct: 1201 HQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGR 1260

Query: 1229 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1288
            CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES
Sbjct: 1261 CICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDES 1320

Query: 1289 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1348
            EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG
Sbjct: 1321 EDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECG 1380

Query: 1349 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1408
            GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI
Sbjct: 1381 GQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTI 1440

Query: 1409 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTN 1468
            RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ            
Sbjct: 1441 RSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ------------ 1488

Query: 1469 TASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1528
                     EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF
Sbjct: 1489 ---------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDF 1539

Query: 1529 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1588
            CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR
Sbjct: 1540 CNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVR 1599

Query: 1589 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1648
            IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK
Sbjct: 1600 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1659

Query: 1649 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1708
            DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL
Sbjct: 1660 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1719

Query: 1709 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1768
            LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV
Sbjct: 1720 LHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLV 1779

Query: 1769 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1828
            PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR
Sbjct: 1780 PEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTR 1839

Query: 1829 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1888
            DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE
Sbjct: 1840 DVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAE 1899

Query: 1889 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1948
            QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK
Sbjct: 1900 QVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKK 1959

Query: 1949 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2008
            CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP
Sbjct: 1960 CSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERP 2019

Query: 2009 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2068
            AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA
Sbjct: 2020 AGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLA 2079

Query: 2069 IFIYAFPNYAAMKLVKPFS 2087
            IFIYAFPNYAAMKLVKPFS
Sbjct: 2080 IFIYAFPNYAAMKLVKPFS 2098


>gi|195976766 dysferlin isoform 7 [Homo sapiens]
          Length = 2112

 Score = 4168 bits (10809), Expect = 0.0
 Identities = 2045/2133 (95%), Positives = 2050/2133 (96%), Gaps = 67/2133 (3%)

Query: 1    MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
            ML   ++ A N+ +   D  SD   S  F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1    MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60

Query: 60   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
            DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61   DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120

Query: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152
            QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA                           
Sbjct: 121  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180

Query: 153  ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208
                DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181  PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240

Query: 209  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268
            SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241  SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300

Query: 269  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328
            NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301  NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360

Query: 329  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388
            FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361  FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420

Query: 389  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448
            EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421  EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480

Query: 449  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 494
            PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE              +
Sbjct: 481  PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540

Query: 495  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 554
            DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 541  DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600

Query: 555  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 614
            EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 601  EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660

Query: 615  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 674
            LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 661  LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720

Query: 675  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 734
            LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 721  LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780

Query: 735  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 794
            SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 781  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840

Query: 795  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 854
            VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 841  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900

Query: 855  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 914
            QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 901  QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960

Query: 915  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 974
            DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 961  DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020

Query: 975  PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1034
            PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080

Query: 1035 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1094
            DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140

Query: 1095 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1154
            VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200

Query: 1155 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1214
            KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260

Query: 1215 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1274
            YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320

Query: 1275 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1334
            GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380

Query: 1335 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1394
            LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440

Query: 1395 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1454
            RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500

Query: 1455 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1514
            IQ                     EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1501 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1539

Query: 1515 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1574
            QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1540 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1599

Query: 1575 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1634
            HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1600 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1659

Query: 1635 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1694
            GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1660 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1719

Query: 1695 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1754
            GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1720 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1779

Query: 1755 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1814
            ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1780 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1839

Query: 1815 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1874
            ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1840 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1899

Query: 1875 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1934
            NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1900 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1959

Query: 1935 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 1994
            DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1960 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2019

Query: 1995 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2054
            TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2020 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2079

Query: 2055 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2087
            ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2080 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2112


>gi|19718759 myoferlin isoform b [Homo sapiens]
          Length = 2048

 Score = 2380 bits (6167), Expect = 0.0
 Identities = 1179/2112 (55%), Positives = 1511/2112 (71%), Gaps = 93/2112 (4%)

Query: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
            MLRV +  A N+        D   S +F   KK+TK + N +NPVWNE  E+DL+GIPLD
Sbjct: 1    MLRVIVESASNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLD 60

Query: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLVL 119
              S L ++VKD ET+G+N+ +G A V L+++    S S  +    LL+ K Q TGA++ L
Sbjct: 61   FSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATIDL 120

Query: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
             + Y P     P  P P  L   P++P +       GEED  D+    +          G
Sbjct: 121  VIGYDP-----PSAPHPNDLS-GPSVPGMG----GDGEEDEGDEDRLDNAVR-------G 163

Query: 180  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
            PG      K P          +R      SR++LS+KPQDFQIRV+VIEGRQL G NI+P
Sbjct: 164  PGP-----KGPVGTVSEAQLARRLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRP 218

Query: 240  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
            VVKV   GQT RTRI +GN+P F+E  F+N+  +P EL DE I I V +S SLR D L+G
Sbjct: 219  VVKVHVCGQTHRTRIKRGNNPFFDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLMG 278

Query: 300  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
            EF++DVG +Y EP HA +RKWLLL+DP+D S+G++GY+K S+ VLG GDE P ER+D   
Sbjct: 279  EFKIDVGFVYDEPGHAVMRKWLLLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERRDRDN 338

Query: 360  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
            D +D+ESNLL P G+ALR   F LK++RAED+PQMDDA    VK+IFG  ++KKNLVDPF
Sbjct: 339  DSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPF 398

Query: 420  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
            VEVSFAGK +C+ I+EK ANP+WNQ + L   FPS+CEK+++ I DWDRLT ND+V TTY
Sbjct: 399  VEVSFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTY 458

Query: 480  LSMSKISAPGGEIEV---DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGV 536
            L +SKI+A GGE+EV   +  +GF+PTFGPCY+NLYGSPRE+TGFPDPY ELNTGKGEGV
Sbjct: 459  LHLSKIAASGGEVEVNTGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNTGKGEGV 518

Query: 537  AYRGRLLLSLETKLVE-HSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDD 595
            AYRGR+L+ L T L +   ++K+E +  DD+L VEKY RRRKYSL A F+SATMLQDV +
Sbjct: 519  AYRGRILVELATFLEKTPPDKKLEPISNDDLLVVEKYQRRRKYSLSAVFHSATMLQDVGE 578

Query: 596  AIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDIS 655
            AIQFEVSIGNYGNKFD TC PLASTTQYSRAVFDG +YYYLPW + KPVV L+SYWEDIS
Sbjct: 579  AIQFEVSIGNYGNKFDTTCKPLASTTQYSRAVFDGNYYYYLPWAHTKPVVTLTSYWEDIS 638

Query: 656  HRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHE 715
            HR++  N LL +A+RL+  +E +   ++ +     +  L  +L DE+I      L     
Sbjct: 639  HRLDAVNTLLAMAERLQTNIEALKSGIQGKIPANQLAELWLKLIDEVIEDTRYTLPLTEG 698

Query: 716  TPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNS 775
              + T LD  + +LR+  LSQI EAA+ ++   +++ + L + EDWL +L  L EEPQNS
Sbjct: 699  KANVTVLDTQIRKLRSRSLSQIHEAAVRMRSEATDVKSTLAEIEDWLDKLMQLTEEPQNS 758

Query: 776  LPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMP 835
            +PDI+IWM++G+KR+AY R+PAHQVL+S  G N  GK CGK QTIFLKYP EK  G ++P
Sbjct: 759  MPDIIIWMIRGEKRLAYARIPAHQVLYSTSGENASGKYCGKTQTIFLKYPQEKNNGPKVP 818

Query: 836  VQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT-YPKFSDVT 894
            V++RV +W GLS  EK+FN FAEG  +VFAE YEN+    + G WGT+GL    KFSDVT
Sbjct: 819  VELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQA--LMFGKWGTSGLVGRHKFSDVT 876

Query: 895  GKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYM 954
            GKIKL ++ F P  GW W G+W V PE++LL + DAGH  F +EV++N++R PGG W   
Sbjct: 877  GKIKLKREFFLPPKGWEWEGEWIVDPERSLLTEADAGHTEFTDEVYQNESRYPGGDWKPA 936

Query: 955  SDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWV 1014
             D YTD NG+K     ++ CP GW+WED+ WS D+NRAVDE+GWEY ITIPP+ KPK WV
Sbjct: 937  EDTYTDANGDKAASPSELTCPPGWEWEDDAWSYDINRAVDEKGWEYGITIPPDHKPKSWV 996

Query: 1015 PAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEG-EGWEYASLFGWKFHLEYRKTD 1073
             AEKMY+THRRRR VR R++DL+Q  +       E +  EGWEYASL GWKFH + R +D
Sbjct: 997  AAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELQDQEGWEYASLIGWKFHWKQRSSD 1056

Query: 1074 AFRRRRWRRRMEPLEKTGPAAVFALEGALGGVM----DDKS-EDSMSVSTLSFGVNRPTI 1128
             FRRRRWRR+M P E  G AA+F LEGALG       D+KS E     +T  FG N P +
Sbjct: 1057 TFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGDEKSLEKQKHSATTVFGANTPIV 1116

Query: 1129 SCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQT 1188
            SC FD    YHLRCY+YQAR+L A+DKDSFSDPYA + FLH+S+ T ++ +TLNPTWDQT
Sbjct: 1117 SCNFDRVYIYHLRCYVYQARNLLALDKDSFSDPYAHICFLHRSKTTEIIHSTLNPTWDQT 1176

Query: 1189 LIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQP------SLERMPRLA 1242
            +IF E+EI+GEP TV + PP +++EL+D+D  G DEF+GR I  P       ++  P+L 
Sbjct: 1177 IIFDEVEIYGEPQTVLQNPPKVIMELFDNDQVGKDEFLGRSIFSPVVKLNSEMDITPKLL 1236

Query: 1243 WFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREA 1302
            W P+  G +  G++L + ELI R K                     + ++LP  PPQR  
Sbjct: 1237 WHPVMNGDKACGDVLVTAELILRGK---------------------DGSNLPILPPQRAP 1275

Query: 1303 NIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRK 1362
            N+YMVPQ I+P +Q TAIEILAWGLRNMK++Q+A+I+SPSLVVECGG+ V+S VI+NL+K
Sbjct: 1276 NLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSPSLVVECGGERVESVVIKNLKK 1335

Query: 1363 NPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSA- 1421
             PNF    LFM+V LP+EELY PP+ +KVID+RQFGR+PVVGQCTI  L+ F CDPY+  
Sbjct: 1336 TPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTIERLDRFRCDPYAGK 1395

Query: 1422 ESPSPQGGPDDVSLLS--PGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEE 1479
            E   PQ      SLLS  P  D++I+++D +PL+  +L +                  EE
Sbjct: 1396 EDIVPQ---LKASLLSAPPCRDIVIEMEDTKPLLASKLTE-----------------KEE 1435

Query: 1480 EFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKT 1539
            E +DWWSKF+AS GE EKCG Y++K +  LK+Y+ +LENV  FEGL+DF +TFKLYRGK+
Sbjct: 1436 EIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLTDFSDTFKLYRGKS 1495

Query: 1540 QEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQP 1599
             +E EDPSV+GEFKG F+IYPLP+DP++P PPRQF +L    PQEC VRIYIVR   LQP
Sbjct: 1496 -DENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQECTVRIYIVRGLELQP 1554

Query: 1600 KDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDL 1659
            +D NG CDPYIKI++GKK + D+D+YIP TL PVFG+M+EL+C LP EKDLKI++YDYD 
Sbjct: 1555 QDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEKDLKISVYDYDT 1614

Query: 1660 LSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVK 1719
             ++DEK+GET++DLENR LS+FG+ CG+P+ YCVSG N WRDQLRP+QLL    +     
Sbjct: 1615 FTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPTQLLQNVARFKGFP 1674

Query: 1720 APVYRTD--RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPL 1777
             P+   D  R+ +  ++YS++E EA +I + HLG  EERLALH+L+ QGLVPEHVE+R L
Sbjct: 1675 QPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRTQGLVPEHVETRTL 1734

Query: 1778 YSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSL 1837
            +S  QP+I QGKLQMWVD+FPK+LG PGPPFNITPR+A++++LR IIWNT+DVILD+ S+
Sbjct: 1735 HSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVIIWNTKDVILDEKSI 1794

Query: 1838 TGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKD 1897
            TGE+MSDIYVKGW+ G EE+KQKTDVHYRSL GEGNFNWRF+FPFDYLPAEQ+C +AKK+
Sbjct: 1795 TGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDYLPAEQLCIVAKKE 1854

Query: 1898 AFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD- 1956
             FW +D+TE +IP R++ QIWDNDKFS DD+LG L+LDL     PAK+ +KC LD + D 
Sbjct: 1855 HFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAKSPEKCRLDMIPDL 1914

Query: 1957 -AFHP--EWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGR 2013
             A +P      SLFEQK++KGWWPC AE+   +++AGK+EMTLEI+ E E +ERPAG+GR
Sbjct: 1915 KAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEILNEKEADERPAGKGR 1974

Query: 2014 DEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYA 2073
            DEPNMNPKL+ P RP+TSFLWFT+P KTMKFI+WRRF+W II  + L ILLLF+A+ +Y+
Sbjct: 1975 DEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLFLLILLLFVAVLLYS 2034

Query: 2074 FPNYAAMKLVKP 2085
             PNY +MK+VKP
Sbjct: 2035 LPNYLSMKIVKP 2046


>gi|7305053 myoferlin isoform a [Homo sapiens]
          Length = 2061

 Score = 2372 bits (6147), Expect = 0.0
 Identities = 1178/2125 (55%), Positives = 1510/2125 (71%), Gaps = 106/2125 (4%)

Query: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
            MLRV +  A N+        D   S +F   KK+TK + N +NPVWNE  E+DL+GIPLD
Sbjct: 1    MLRVIVESASNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLD 60

Query: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLVL 119
              S L ++VKD ET+G+N+ +G A V L+++    S S  +    LL+ K Q TGA++ L
Sbjct: 61   FSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATIDL 120

Query: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
             + Y P     P  P P  L   P++P +       GEED  D+    +          G
Sbjct: 121  VIGYDP-----PSAPHPNDLS-GPSVPGMG----GDGEEDEGDEDRLDNAVR-------G 163

Query: 180  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
            PG      K P          +R      SR++LS+KPQDFQIRV+VIEGRQL G NI+P
Sbjct: 164  PGP-----KGPVGTVSEAQLARRLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRP 218

Query: 240  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
            VVKV   GQT RTRI +GN+P F+E  F+N+  +P EL DE I I V +S SLR D L+G
Sbjct: 219  VVKVHVCGQTHRTRIKRGNNPFFDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLMG 278

Query: 300  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
            EF++DVG +Y EP HA +RKWLLL+DP+D S+G++GY+K S+ VLG GDE P ER+D   
Sbjct: 279  EFKIDVGFVYDEPGHAVMRKWLLLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERRDRDN 338

Query: 360  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
            D +D+ESNLL P G+ALR   F LK++RAED+PQMDDA    VK+IFG  ++KKNLVDPF
Sbjct: 339  DSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPF 398

Query: 420  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
            VEVSFAGK +C+ I+EK ANP+WNQ + L   FPS+CEK+++ I DWDRLT ND+V TTY
Sbjct: 399  VEVSFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTY 458

Query: 480  LSMSKISAPGGEIE----------------VDDYLGFLPTFGPCYINLYGSPREFTGFPD 523
            L +SKI+A GGE+E                 +  +GF+PTFGPCY+NLYGSPRE+TGFPD
Sbjct: 459  LHLSKIAASGGEVEDFSSSGTGAASYTVNTGETEVGFVPTFGPCYLNLYGSPREYTGFPD 518

Query: 524  PYTELNTGKGEGVAYRGRLLLSLETKLVE-HSEQKVEDLPADDILRVEKYLRRRKYSLFA 582
            PY ELNTGKGEGVAYRGR+L+ L T L +   ++K+E +  DD+L VEKY RRRKYSL A
Sbjct: 519  PYDELNTGKGEGVAYRGRILVELATFLEKTPPDKKLEPISNDDLLVVEKYQRRRKYSLSA 578

Query: 583  AFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVK 642
             F+SATMLQDV +AIQFEVSIGNYGNKFD TC PLASTTQYSRAVFDG +YYYLPW + K
Sbjct: 579  VFHSATMLQDVGEAIQFEVSIGNYGNKFDTTCKPLASTTQYSRAVFDGNYYYYLPWAHTK 638

Query: 643  PVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDEL 702
            PVV L+SYWEDISHR++  N LL +A+RL+  +E +   ++ +     +  L  +L DE+
Sbjct: 639  PVVTLTSYWEDISHRLDAVNTLLAMAERLQTNIEALKSGIQGKIPANQLAELWLKLIDEV 698

Query: 703  IAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWL 762
            I      L       + T LD  + +LR+  LSQI EAA+ ++   +++ + L + EDWL
Sbjct: 699  IEDTRYTLPLTEGKANVTVLDTQIRKLRSRSLSQIHEAAVRMRSEATDVKSTLAEIEDWL 758

Query: 763  LRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFL 822
             +L  L EEPQNS+PDI+IWM++G+KR+AY R+PAHQVL+S  G N  GK CGK QTIFL
Sbjct: 759  DKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGENASGKYCGKTQTIFL 818

Query: 823  KYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGT 882
            KYP EK  G ++PV++RV +W GLS  EK+FN FAEG  +VFAE YEN+    + G WGT
Sbjct: 819  KYPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQA--LMFGKWGT 876

Query: 883  TGLT-YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFE 941
            +GL    KFSDVTGKIKL ++ F P  GW W G+W V PE++LL + DAGH  F +EV++
Sbjct: 877  SGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGEWIVDPERSLLTEADAGHTEFTDEVYQ 936

Query: 942  NQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYS 1001
            N++R PGG W    D YTD NG+K     ++ CP GW+WED+ WS D+NRAVDE+GWEY 
Sbjct: 937  NESRYPGGDWKPAEDTYTDANGDKAASPSELTCPPGWEWEDDAWSYDINRAVDEKGWEYG 996

Query: 1002 ITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEG-EGWEYASL 1060
            ITIPP+ KPK WV AEKMY+THRRRR VR R++DL+Q  +       E +  EGWEYASL
Sbjct: 997  ITIPPDHKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELQDQEGWEYASL 1056

Query: 1061 FGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVM----DDKS-EDSMS 1115
             GWKFH + R +D FRRRRWRR+M P E  G AA+F LEGALG       D+KS E    
Sbjct: 1057 IGWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGDEKSLEKQKH 1116

Query: 1116 VSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTV 1175
             +T  FG N P +SC FD    YHLRCY+YQAR+L A+DKDSFSDPYA + FLH+S+ T 
Sbjct: 1117 SATTVFGANTPIVSCNFDRVYIYHLRCYVYQARNLLALDKDSFSDPYAHICFLHRSKTTE 1176

Query: 1176 VVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQP-- 1233
            ++ +TLNPTWDQT+IF E+EI+GEP TV + PP +++EL+D+D  G DEF+GR I  P  
Sbjct: 1177 IIHSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPKVIMELFDNDQVGKDEFLGRSIFSPVV 1236

Query: 1234 ----SLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1289
                 ++  P+L W P+  G +  G++L + ELI R K                     +
Sbjct: 1237 KLNSEMDITPKLLWHPVMNGDKACGDVLVTAELILRGK---------------------D 1275

Query: 1290 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1349
             ++LP  PPQR  N+YMVPQ I+P +Q TAIEILAWGLRNMK++Q+A+I+SPSLVVECGG
Sbjct: 1276 GSNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSPSLVVECGG 1335

Query: 1350 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1409
            + V+S VI+NL+K PNF    LFM+V LP+EELY PP+ +KVID+RQFGR+PVVGQCTI 
Sbjct: 1336 ERVESVVIKNLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTIE 1395

Query: 1410 SLESFLCDPYSA-ESPSPQGGPDDVSLLS--PGEDVLIDIDDKEPLIPIQLADGLSSLAP 1466
             L+ F CDPY+  E   PQ      SLLS  P  D++I+++D +PL+  +L +       
Sbjct: 1396 RLDRFRCDPYAGKEDIVPQ---LKASLLSAPPCRDIVIEMEDTKPLLASKLTE------- 1445

Query: 1467 TNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLS 1526
                       EEE +DWWSKF+AS GE EKCG Y++K +  LK+Y+ +LENV  FEGL+
Sbjct: 1446 ----------KEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLT 1495

Query: 1527 DFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECL 1586
            DF +TFKLYRGK+ +E EDPSV+GEFKG F+IYPLP+DP++P PPRQF +L    PQEC 
Sbjct: 1496 DFSDTFKLYRGKS-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQECT 1554

Query: 1587 VRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPL 1646
            VRIYIVR   LQP+D NG CDPYIKI++GKK + D+D+YIP TL PVFG+M+EL+C LP 
Sbjct: 1555 VRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQ 1614

Query: 1647 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPS 1706
            EKDLKI++YDYD  ++DEK+GET++DLENR LS+FG+ CG+P+ YCVSG N WRDQLRP+
Sbjct: 1615 EKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPT 1674

Query: 1707 QLLHLFCQQHRVKAPVYRTD--RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQ 1764
            QLL    +      P+   D  R+ +  ++YS++E EA +I + HLG  EERLALH+L+ 
Sbjct: 1675 QLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRT 1734

Query: 1765 QGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCII 1824
            QGLVPEHVE+R L+S  QP+I QGKLQMWVD+FPK+LG PGPPFNITPR+A++++LR II
Sbjct: 1735 QGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVII 1794

Query: 1825 WNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDY 1884
            WNT+DVILD+ S+TGE+MSDIYVKGW+ G EE+KQKTDVHYRSL GEGNFNWRF+FPFDY
Sbjct: 1795 WNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDY 1854

Query: 1885 LPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAK 1944
            LPAEQ+C +AKK+ FW +D+TE +IP R++ QIWDNDKFS DD+LG L+LDL     PAK
Sbjct: 1855 LPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAK 1914

Query: 1945 TAKKCSLDQLDD--AFHP--EWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVA 2000
            + +KC LD + D  A +P      SLFEQK++KGWWPC AE+   +++AGK+EMTLEI+ 
Sbjct: 1915 SPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEILN 1974

Query: 2001 ESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIIL 2060
            E E +ERPAG+GRDEPNMNPKL+ P RP+TSFLWFT+P KTMKFI+WRRF+W II  + L
Sbjct: 1975 EKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLFL 2034

Query: 2061 FILLLFLAIFIYAFPNYAAMKLVKP 2085
             ILLLF+A+ +Y+ PNY +MK+VKP
Sbjct: 2035 LILLLFVAVLLYSLPNYLSMKIVKP 2059


>gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens]
          Length = 2093

 Score = 1432 bits (3708), Expect = 0.0
 Identities = 860/2196 (39%), Positives = 1216/2196 (55%), Gaps = 278/2196 (12%)

Query: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
            MLR+ +  A+ +  P   +     S  F  +KKRT+V++ + +PVWNE   W L   PL+
Sbjct: 1    MLRLVVQSAK-IDPPLAPLPRPCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLE 58

Query: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVL 119
              S L V ++D  +  + RF+G A V L+ +L  PS +    +  LL+   +PT  ++ L
Sbjct: 59   NDSFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTL 118

Query: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
            QV++                     + + D+   TG E+     G+T  EA         
Sbjct: 119  QVAH---------------------MSNQDI-EKTGAEDHL---GITAREA--------- 144

Query: 180  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
                   +KL        PG        T+ + LS KPQ FQ+RV+V E RQL G NIKP
Sbjct: 145  -----ASQKLM------VPG-------STAHRALSSKPQHFQVRVKVFEARQLMGNNIKP 186

Query: 240  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
            VVKV+ AGQ  +TRI  GN+P FNE  F N  + P + FDE I I               
Sbjct: 187  VVKVSIAGQQHQTRIKMGNNPFFNEIFFQNFHEVPAKFFDETILI--------------- 231

Query: 300  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
              + D+G IY  P H  LRKWL L  P++  +G  GYLK ++  LG GD+A +++K    
Sbjct: 232  --QTDIGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQK-LLY 288

Query: 360  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
              +D +  + +   V +  A+  L ++ AEDL                    K   V+P 
Sbjct: 289  GTDDTDIQIFKSAVVPINMAYLQLFIYCAEDL-----------------HLKKHQSVNPQ 331

Query: 420  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
            +EV   G+ L + +  +T NP WNQ +T     P +   ++ R++D  +    D + T  
Sbjct: 332  LEVELIGEKLRTHMQTQTDNPIWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTAS 391

Query: 480  LSMSKISAPGGEIEVDD-----------YLGFLPTFGPCYINLYGSPREFTGFPDPYTEL 528
            LS+++IS+ G EIE              Y GFLP FGP ++ L+G  +      +    +
Sbjct: 392  LSLNQISSTGEEIEGKQSLEPTSYTPRVYSGFLPCFGPSFLTLHGGKKAPFRIQEEGACI 451

Query: 529  NTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSAT 588
                 +G+AYRGR+ L L T++  + +  ++DL + ++ R+EK+  R+KY L   F S T
Sbjct: 452  PDSVRDGLAYRGRVFLELITQIKSYQDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCT 510

Query: 589  MLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLS 648
            M+ +  + I FEVSIG+YGNK D+   PL S+T YS  ++DG  Y+Y+PW N KPVV ++
Sbjct: 511  MMPNFKELIHFEVSIGHYGNKMDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVT 570

Query: 649  SYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVA--QLTDELIAGC 706
            S WED+S R+   N L    DRL+A L+     LK+  + +D   L    +L  EL   C
Sbjct: 571  SNWEDVSFRMNCLNLLHFTRDRLKANLD----TLKSTRNPKDPALLYQWEKLLRELAEDC 626

Query: 707  SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 766
             +PL  +   P AT LD+  +QLR+  L +     LA K   ++    +  AEDWL RL 
Sbjct: 627  KRPLPCMTYQPKATSLDRKRWQLRSLLLQE-----LAQKAKQAKPKDMVATAEDWLYRLN 681

Query: 767  ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 826
             +  EPQ  LPD++IW++  ++RVAY +VPAH VLFS  GA + G+ CGK+QT+FL+YP 
Sbjct: 682  TVLPEPQMGLPDVMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPE 741

Query: 827  EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 886
             +     +P  +RV +W G   D K+     +G  +V+AE YEN+ K      WG  GL 
Sbjct: 742  GEGQKDVLPAHLRVCMWLGNVTDSKDLQLLRQGDTAVYAEMYENQAKYK--DQWGQQGLY 799

Query: 887  Y-PKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 945
            + P FSDV G   LP   F+P  GW W   W V P++ LL D+D      +EEV+ENQ R
Sbjct: 800  HCPNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGR 859

Query: 946  LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1005
               G W   +   TDVNG+ +  +++++CP GW ++ ++W  +LN AVD   WEY + IP
Sbjct: 860  DTRGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFK-KDWVVELNHAVDS--WEYGVGIP 916

Query: 1006 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQ----------AEAEGEGW 1055
            P   P+ W P EK Y++ RRRRW R+R R+  ++     H Q          A+ E EGW
Sbjct: 917  PSGLPQVWSPVEKTYHSCRRRRWARVRFRNHGELS----HEQETLSFLQLGLAKGEEEGW 972

Query: 1056 EYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGAL----GGVMDD--- 1108
            EY + FG KFHL  +    FRRR WRRR+ P +  G A +F LEG+L    G V ++   
Sbjct: 973  EYDT-FGSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSLACEGGSVREEGDW 1031

Query: 1109 ------------------------------KSEDSMSVSTLSFGVNR------------- 1125
                                          K EDS    T  +G++R             
Sbjct: 1032 AWARGNRSSTQEPQGRLSWVQAMDLKYHAGKEEDS---KTWPWGLDRQFRDPQRQDTRPP 1088

Query: 1126 --PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNP 1183
              P I C F+  + Y L CY+YQAR+L +    +F  P+  V FL+ SQ T  ++++  P
Sbjct: 1089 NLPFIYCTFNKPHYYQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGP 1148

Query: 1184 TWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL------ER 1237
            TW QTLIF  + ++  P    E PP +V+EL+  D +G +   GR +  P +        
Sbjct: 1149 TWAQTLIFQHLLLYENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRI 1208

Query: 1238 MPRLAWFPLTRG-SQPSGELLASFELI-QREKPAIHHIPGFEVQETSRILDESEDTDLPY 1295
            +P + W PL +   +  GE+LAS ELI Q EK     +P   V               P+
Sbjct: 1209 LPPMRWHPLVKELGKEEGEILASCELILQTEKLGEKQLPILSV---------------PW 1253

Query: 1296 PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSC 1355
                 +   Y +P++I+P ++R AIEILAWGLRNMK       SSP L+VE G +++++ 
Sbjct: 1254 -----KNGAYTLPKSIQPTIKRMAIEILAWGLRNMKK-----ASSPQLLVEFGEESLRTE 1303

Query: 1356 VIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLES 1413
             IR+ + NPNF      L + V++P EE Y  P+ VKV+DN  FG++ V GQ  I  L+ 
Sbjct: 1304 PIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQP 1363

Query: 1414 FLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPP 1473
            + CDP++ +   P+               L  + +K+        D L  L         
Sbjct: 1364 YFCDPWAQDYMHPK---------------LPTLSEKKH------QDFLGYLYRKFWFK-- 1400

Query: 1474 SSPHEEEF---IDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCN 1530
            SS  E+E+   +DWWSK F +  E +    Y  KD+ TLKVY+ +LE V AF+GL DFC 
Sbjct: 1401 SSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQ 1459

Query: 1531 TFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVR 1588
            TFKLY+   ++   D  V+GEFKGLF+IYP PE+P  P PP QF     +   PQ CLVR
Sbjct: 1460 TFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVR 1516

Query: 1589 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1648
            +Y+VRA  LQP+D NG CDPY+ + +GK  + ++D Y P TL+P+FG MFELTC +PLEK
Sbjct: 1517 VYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEK 1576

Query: 1649 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1708
            DL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS L
Sbjct: 1577 DLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYL 1636

Query: 1709 LHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQ 1765
            L  + ++  +  P++    D V +  K++ ++  E  + P  H LGP +ERLAL++L  Q
Sbjct: 1637 LERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQ 1695

Query: 1766 GLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRAR--------- 1816
            GLVPEHVE+R LYS  QP I+QGK+QMWVD+FPK LG PGP  NI PR+ +         
Sbjct: 1696 GLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGH 1755

Query: 1817 RFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNW 1876
            R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+  QKTD+HY SL GE +FNW
Sbjct: 1756 RYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNW 1815

Query: 1877 RFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDL 1936
            RFIF  DYL AE+ C  ++KD  W LD T  K PAR++ Q+WDND FS DDFLG L+LDL
Sbjct: 1816 RFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDL 1875

Query: 1937 NRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILA 1989
            + MP PA+ AK+CS+  +D    P+W         SLF++KTV GWWPC   +G K  L+
Sbjct: 1876 SDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLS 1933

Query: 1990 GKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRR 2049
            GK++M+LEI++E E   +PAG+G+ EPN  P L  P R +TSF W  SP +   +I W+R
Sbjct: 1934 GKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKR 1993

Query: 2050 FRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2085
            +R+ +I F+++ I+ L L  FIY+ P+Y AM  +KP
Sbjct: 1994 YRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 2029


>gi|35493868 otoferlin isoform b [Homo sapiens]
          Length = 1230

 Score =  726 bits (1875), Expect = 0.0
 Identities = 409/1057 (38%), Positives = 590/1057 (55%), Gaps = 128/1057 (12%)

Query: 1126 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1185
            P +S ++     + LR +MYQAR L A D    SDP+A V F++QSQ T V+  TL PTW
Sbjct: 201  PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260

Query: 1186 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1238
            DQ L+F  +E++GE   + + PP IV+E+YD D+ G  +FMGR   +P ++         
Sbjct: 261  DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320

Query: 1239 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1295
               P+L ++ + RG+  +G+LLA+FEL+Q                    +  +   DLP 
Sbjct: 321  RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360

Query: 1296 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1352
               P       I  VP  I+P L +  +E+L WGLR++K   LA +  P + +EC G+ V
Sbjct: 361  INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420

Query: 1353 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1412
            QS +I N +KNPNF+    + EV LP  EL  PP+ ++V+D R FGR  +VG   + SL 
Sbjct: 421  QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480

Query: 1413 SFLCDPYSAESPSPQGGPDDVSLLSPGEDV-----LIDID-DKEPLIPIQLADGLSSLAP 1466
             F+  P    +PS     + V  + P   +     ++ +D   E ++ + +A+       
Sbjct: 481  RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540

Query: 1467 TNTAS---PPSSPHEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1505
                +   P     +E  +DWWSK+FASI        ++E  G  LE+            
Sbjct: 541  KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600

Query: 1506 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1528
                                                  D LKVY  +LE+   F+   D+
Sbjct: 601  SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658

Query: 1529 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1578
             +TF L RGKT ++    TE+  ++G FKG   +Y  PLPED +           F  + 
Sbjct: 659  LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718

Query: 1579 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1638
            +  P   LVR+Y+VRA  L P D NGK DPYI I +GK  + D++NYI   L PVFGK F
Sbjct: 719  SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778

Query: 1639 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1698
            ++  + P+E  L + +YD+DL+  D+ IGET +DLENR  SK  A CG+ QTY   G N 
Sbjct: 779  DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838

Query: 1699 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1756
            WRD ++PSQ+L   C+  +V  P +    RV   ++ ++   EIE     N    P +E 
Sbjct: 839  WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895

Query: 1757 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1808
            +AL  L+           LVPEHVE+RPL +P +P IEQG+L++WVD+FP  +  PG P 
Sbjct: 896  VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955

Query: 1809 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1867
            +I+PR+ +++ LR IIWNT +V+L DD   TGEK SDI+V+GW+ G +E KQ TDVHY S
Sbjct: 956  DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015

Query: 1868 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1927
            L GEGNFNWR++FPFDYL AE+   I+KK++ +  D+TE KIPAR+  QIWD D FS DD
Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075

Query: 1928 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 1986
            FLG+++LDLNR P+ AKTAK+C+++           VS+F+QK VKGWWP +A  E ++ 
Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134

Query: 1987 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2046
             L GK+E  L ++   E E+ P G  R+EP+    LE P RPDTSF+WF +P K+ ++ L
Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTSFIWFLNPLKSARYFL 1191

Query: 2047 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2083
            W  +RW ++  ++L +LLL LA+F+Y+ P Y   K++
Sbjct: 1192 WHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1228



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%)

Query: 700 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 754
           +EL  GC +   L D  +  S+ T LD+   +     L  + + A  L+  +    +   
Sbjct: 18  EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77

Query: 755 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 814
           L   +++L +LR LA+EPQ+S+PDI IWM+  +KRVAY RVP+  +LFS       GK+C
Sbjct: 78  LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136

Query: 815 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 853
            K++T+FLK P ++  G A   VQ +V+  LW GLS   KEF
Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178



 Score = 33.9 bits (76), Expect = 1.7
 Identities = 13/37 (35%), Positives = 21/37 (56%)

Query: 408 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 444
           F ++   L DPF  V F  +  C+++L +T  P W+Q
Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262


>gi|35493853 otoferlin isoform c [Homo sapiens]
          Length = 1307

 Score =  723 bits (1867), Expect = 0.0
 Identities = 418/1084 (38%), Positives = 593/1084 (54%), Gaps = 162/1084 (14%)

Query: 1126 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1185
            P +S ++     + LR +MYQAR L A D    SDP+A V F++QSQ T V+  TL PTW
Sbjct: 258  PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 317

Query: 1186 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1238
            DQ L+F  +E++GE   + + PP IV+E+YD D+ G  +FMGR   +P ++         
Sbjct: 318  DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 377

Query: 1239 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1295
               P+L ++ + RG+  +G+LLA+FEL+Q                    +  +   DLP 
Sbjct: 378  RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 417

Query: 1296 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1352
               P       I  VP  I+P L +  +E+L WGLR++K   LA +  P + +EC G+ V
Sbjct: 418  INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 477

Query: 1353 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1412
            QS +I N +KNPNF+    + EV LP  EL  PP+ ++V+D R FGR  +VG   + SL 
Sbjct: 478  QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 537

Query: 1413 SFLCDPYSAESPS--------------PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLA 1458
             F+  P    +PS                GG    S  S GE V+      EP +PI+  
Sbjct: 538  RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGS---SSHSTGEVVVT----MEPEVPIKKL 590

Query: 1459 DGLSSLAPTNTA----------------------SPPSSPHEEEFIDWWSKFFASIG--- 1493
            + +  L  T+ A                       P     +E  +DWWSK+FASI    
Sbjct: 591  ETMVKLDATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMK 650

Query: 1494 ----EREKCGSYLEKD-------------------------------------------- 1505
                ++E  G  LE+                                             
Sbjct: 651  EQLRQQEPSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEK 710

Query: 1506 ----FDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFK 1557
                 D LKVY  +LE+   F+   D+ +TF L RGKT ++    TE+  ++G FKG   
Sbjct: 711  KKPKIDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLC 768

Query: 1558 IY--PLPEDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIK 1611
            +Y  PLPED +           F  + +  P   LVR+Y+VRA  L P D NGK DPYI 
Sbjct: 769  VYKVPLPEDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIA 828

Query: 1612 ISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVV 1671
            I +GK  + D++NYI   L PVFGK F++  + P+E  L + +YD+DL+  D+ IGET +
Sbjct: 829  IRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKI 888

Query: 1672 DLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMF 1730
            DLENR  SK  A CG+ QTY   G N WRD ++PSQ+L   C+  +V  P +    RV  
Sbjct: 889  DLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKV 948

Query: 1731 QDKEYS-IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPL 1781
             ++ ++   EIE     N    P +E +AL  L+           LVPEHVE+RPL +P 
Sbjct: 949  ANRVFTGPSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPD 1005

Query: 1782 QPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGE 1840
            +P IEQG+L++WVD+FP  +  PG P +I+PR+ +++ LR IIWNT +V+L DD   TGE
Sbjct: 1006 KPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGE 1065

Query: 1841 KMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFW 1900
            K SDI+V+GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+   I+KK++ +
Sbjct: 1066 KSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMF 1125

Query: 1901 RLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHP 1960
              D+TE KIPAR+  QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++        
Sbjct: 1126 SWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDV 1185

Query: 1961 EWFVSLFEQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMN 2019
               VS+F+QK VKGWWP +A  E ++  L GK+E  L ++   E E+ P G  R+EP+  
Sbjct: 1186 P-LVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD-- 1242

Query: 2020 PKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAA 2079
              LE P RPDTSF+WF +P K+ ++ LW  +RW ++  ++L +LLL LA+F+Y+ P Y  
Sbjct: 1243 -PLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLV 1301

Query: 2080 MKLV 2083
             K++
Sbjct: 1302 KKIL 1305



 Score = 91.3 bits (225), Expect = 9e-18
 Identities = 71/211 (33%), Positives = 110/211 (52%), Gaps = 21/211 (9%)

Query: 651 WEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQ-- 708
           W  I+H  ++Q          E GL  +   +K + S  +    +  + +EL  GC +  
Sbjct: 38  WPSITHTPDSQ----------EEGLNDIQEMIKTEKSYPE--RRLRGVLEELSCGCCRFL 85

Query: 709 PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAALEQAEDWLLRL 765
            L D  +  S+ T LD+   +     L  + + A  L+  +    +   L   +++L +L
Sbjct: 86  SLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKL 145

Query: 766 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 825
           R LA+EPQ+S+PDI IWM+  +KRVAY RVP+  +LFS       GK+C K++T+FLK P
Sbjct: 146 RFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDCAKVKTLFLKLP 204

Query: 826 MEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 853
            ++  G A   VQ +V+  LW GLS   KEF
Sbjct: 205 GKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 235



 Score = 33.9 bits (76), Expect = 1.7
 Identities = 13/37 (35%), Positives = 21/37 (56%)

Query: 408 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 444
           F ++   L DPF  V F  +  C+++L +T  P W+Q
Sbjct: 283 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 319


>gi|34740331 otoferlin isoform a [Homo sapiens]
          Length = 1997

 Score =  723 bits (1867), Expect = 0.0
 Identities = 418/1084 (38%), Positives = 593/1084 (54%), Gaps = 162/1084 (14%)

Query: 1126 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1185
            P +S ++     + LR +MYQAR L A D    SDP+A V F++QSQ T V+  TL PTW
Sbjct: 948  PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 1007

Query: 1186 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1238
            DQ L+F  +E++GE   + + PP IV+E+YD D+ G  +FMGR   +P ++         
Sbjct: 1008 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 1067

Query: 1239 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1295
               P+L ++ + RG+  +G+LLA+FEL+Q                    +  +   DLP 
Sbjct: 1068 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 1107

Query: 1296 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1352
               P       I  VP  I+P L +  +E+L WGLR++K   LA +  P + +EC G+ V
Sbjct: 1108 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 1167

Query: 1353 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1412
            QS +I N +KNPNF+    + EV LP  EL  PP+ ++V+D R FGR  +VG   + SL 
Sbjct: 1168 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 1227

Query: 1413 SFLCDPYSAESPS--------------PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLA 1458
             F+  P    +PS                GG    S  S GE V+      EP +PI+  
Sbjct: 1228 RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGS---SSHSTGEVVVT----MEPEVPIKKL 1280

Query: 1459 DGLSSLAPTNTA----------------------SPPSSPHEEEFIDWWSKFFASIG--- 1493
            + +  L  T+ A                       P     +E  +DWWSK+FASI    
Sbjct: 1281 ETMVKLDATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMK 1340

Query: 1494 ----EREKCGSYLEKD-------------------------------------------- 1505
                ++E  G  LE+                                             
Sbjct: 1341 EQLRQQEPSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEK 1400

Query: 1506 ----FDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFK 1557
                 D LKVY  +LE+   F+   D+ +TF L RGKT ++    TE+  ++G FKG   
Sbjct: 1401 KKPKIDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLC 1458

Query: 1558 IY--PLPEDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIK 1611
            +Y  PLPED +           F  + +  P   LVR+Y+VRA  L P D NGK DPYI 
Sbjct: 1459 VYKVPLPEDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIA 1518

Query: 1612 ISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVV 1671
            I +GK  + D++NYI   L PVFGK F++  + P+E  L + +YD+DL+  D+ IGET +
Sbjct: 1519 IRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKI 1578

Query: 1672 DLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMF 1730
            DLENR  SK  A CG+ QTY   G N WRD ++PSQ+L   C+  +V  P +    RV  
Sbjct: 1579 DLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKV 1638

Query: 1731 QDKEYS-IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPL 1781
             ++ ++   EIE     N    P +E +AL  L+           LVPEHVE+RPL +P 
Sbjct: 1639 ANRVFTGPSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPD 1695

Query: 1782 QPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGE 1840
            +P IEQG+L++WVD+FP  +  PG P +I+PR+ +++ LR IIWNT +V+L DD   TGE
Sbjct: 1696 KPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGE 1755

Query: 1841 KMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFW 1900
            K SDI+V+GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+   I+KK++ +
Sbjct: 1756 KSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMF 1815

Query: 1901 RLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHP 1960
              D+TE KIPAR+  QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++        
Sbjct: 1816 SWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDV 1875

Query: 1961 EWFVSLFEQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMN 2019
               VS+F+QK VKGWWP +A  E ++  L GK+E  L ++   E E+ P G  R+EP+  
Sbjct: 1876 P-LVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD-- 1932

Query: 2020 PKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAA 2079
              LE P RPDTSF+WF +P K+ ++ LW  +RW ++  ++L +LLL LA+F+Y+ P Y  
Sbjct: 1933 -PLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLV 1991

Query: 2080 MKLV 2083
             K++
Sbjct: 1992 KKIL 1995



 Score =  387 bits (994), Expect = e-107
 Identities = 289/929 (31%), Positives = 458/929 (49%), Gaps = 117/929 (12%)

Query: 21  DAYCSAVFAGVKKRTKVIKNSVNPV-WNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNR 79
           D      F G    ++V++N  +   ++E F W +    +D+   L + V ++  +  N+
Sbjct: 18  DRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVAS-SIDRNEMLEIQVFNYSKVFSNK 76

Query: 80  FLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPPPTPL 139
            +G  ++ L++V+    +  +    L+D        SL ++V Y    G V  +     L
Sbjct: 77  LIGTFRMVLQKVVEESHVEVTDT--LIDDNNAIIKTSLCVEVRYQATDGTVGSWDDGDFL 134

Query: 140 -------------EPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPF---LDQSGGPGAP 183
                        E    LP     +   GE+     G +   A            P  P
Sbjct: 135 GDESLQEEEKDSQETDGLLPGSRPSSRPPGEKSFRRAGRSVFSAMKLGKNRSHKEEPQRP 194

Query: 184 TTPRKLPSRPPPHYP----------------------GIKRKRSAPTSRKLLS-DKPQDF 220
             P  L      H                         +  KRS P  +   S  +P D+
Sbjct: 195 DEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTTNVSNKRSKPDIKMEPSAGRPMDY 254

Query: 221 QIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNETLFFNLFDSPGELFD 279
           Q+ + VIE RQL G+N+ PVV V      K T + +  N P +NE   F+   SP  +FD
Sbjct: 255 QVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFD 314

Query: 280 EPIFITVVDSRSL-RTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLK 338
           + I I+V+ S++L R+  L+G F+MDVGT+Y +P H +  KW +LSDPDD S+G +GY+K
Sbjct: 315 KIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISSGLKGYVK 374

Query: 339 TSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGV--ALRGAHFCLKVFRAEDLPQMDD 396
             + V+G GD      K    D++DIE NLL P GV    + A F +K++RAE LP+M+ 
Sbjct: 375 CDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNT 434

Query: 397 AVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMC 456
           ++M NVK+ F  E+  K+LVDP+V+V FAG+   + + + +  P WN+ +    +FP +C
Sbjct: 435 SLMANVKKAFIGEN--KDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLC 492

Query: 457 EKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYINLYGSP 515
           ++M+++I D D++  ND+ + T ++ + KIS  G +       GFLPT GP ++N+YGS 
Sbjct: 493 KRMKVQIRDSDKV--NDVAIGTHFIDLRKISNDGDK-------GFLPTLGPAWVNMYGST 543

Query: 516 REFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYL-- 573
           R +T   D + +LN G GEGV++R RLLL L  ++V+ S     +L +   ++VE+    
Sbjct: 544 RNYT-LLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSN---PELTSSTEVQVEQATPI 599

Query: 574 ------RRRKYSLFAAFYSATML--QDVDDAIQFEVSIGNYGNKFDMTCLP--------- 616
                 +  ++ LF AF  A+M+  ++ D  I FEV+IGNYGN+ D    P         
Sbjct: 600 SESCAGKMEEFFLFGAFLEASMIDRRNGDKPITFEVTIGNYGNEVDGLSRPQRPRPRKEP 659

Query: 617 ------------------------LASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWE 652
                                     S+T   R      +Y++LP+   KP + + S+W 
Sbjct: 660 GDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVTDRNYFHLPYLERKPCIYIKSWWP 719

Query: 653 DISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQ--PL 710
           D   R+   N +  IAD+LE GL  +   +K + S    +  +  + +EL  GC +   L
Sbjct: 720 DQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYP--ERRLRGVLEELSCGCCRFLSL 777

Query: 711 GDIHETPSA-THLDQYLYQLRTHHLSQITEAA--LALKLGHSELPAALEQAEDWLLRLRA 767
            D  +  S+ T LD+   +     L  + + A  L  ++    +   L   +++L +LR 
Sbjct: 778 ADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRF 837

Query: 768 LAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPME 827
           LA+EPQ+S+PDI IWM+  +KRVAY RVP+  +LFS       GK+C K++T+FLK P +
Sbjct: 838 LADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDCAKVKTLFLKLPGK 896

Query: 828 KVPG-ARMPVQIRVK--LWFGLSVDEKEF 853
           +  G A   VQ +V+  LW GLS   KEF
Sbjct: 897 RGFGSAGWTVQAKVELYLWLGLSKQRKEF 925



 Score = 35.4 bits (80), Expect = 0.59
 Identities = 15/31 (48%), Positives = 19/31 (61%)

Query: 18  DISDAYCSAVFAGVKKRTKVIKNSVNPVWNE 48
           D+ D Y    FAG K +T V K+S  P+WNE
Sbjct: 450 DLVDPYVQVFFAGQKGKTSVQKSSYEPLWNE 480



 Score = 33.9 bits (76), Expect = 1.7
 Identities = 13/37 (35%), Positives = 21/37 (56%)

Query: 408  FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 444
            F ++   L DPF  V F  +  C+++L +T  P W+Q
Sbjct: 973  FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 1009



 Score = 32.3 bits (72), Expect = 5.0
 Identities = 13/35 (37%), Positives = 21/35 (60%)

Query: 1160 DPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1194
            DPY  V F  Q  KT V K++  P W++ ++F ++
Sbjct: 453  DPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDL 487


>gi|119120884 fer-1-like 6 [Homo sapiens]
          Length = 1857

 Score =  720 bits (1858), Expect = 0.0
 Identities = 406/1082 (37%), Positives = 585/1082 (54%), Gaps = 145/1082 (13%)

Query: 1116 VSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTV 1175
            +S+   G N P  + ++   + + LR +MYQAR L A D +  SDP+A V+FL   Q T 
Sbjct: 804  MSSKGAGTNHPPSNLLYQEQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSHCQTTK 863

Query: 1176 VVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL 1235
            ++  TL+PTW+Q L+F ++ + G+   +AE PP +VVELYD D  G  E++G  +  P +
Sbjct: 864  IISQTLSPTWNQMLLFNDLVLHGDVKELAESPPLVVVELYDSDAVGKPEYLGATVAAPVV 923

Query: 1236 E------RMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1289
            +        PRL + P+  G+   G+LLA FEL+Q     +  +P               
Sbjct: 924  KLADQDYEPPRLCYHPIFCGNLSGGDLLAVFELLQVPPSGLQGLP--------------- 968

Query: 1290 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1349
                P  PP     IY VP NI+P L +  +E+L WG+R MK  QL ++  P  ++ECGG
Sbjct: 969  ----PVEPPDI-TQIYPVPANIRPVLSKYRVEVLFWGVREMKKVQLLSVDRPQALIECGG 1023

Query: 1350 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1409
            Q V+SCVI++ + NPNF I     EV LP  EL  PP+++ V+D R FGR  +VG  TI 
Sbjct: 1024 QGVKSCVIQSYKNNPNFSIQADAFEVELPENELLHPPLSICVVDWRAFGRSTLVGTYTIN 1083

Query: 1410 SLESFLCDPYSAESPSPQ-------------------GGPDDVSLLSPGEDVLIDID--- 1447
             L+ FLC      +P  Q                    G    S   P + + +D++   
Sbjct: 1084 YLKQFLCKLREPLAPITQVDGTQPGHDISDSLTATESSGAHSSSQDPPADHIYVDVEPPP 1143

Query: 1448 -------DKEPLIPIQLADGLSSLAPTNTASPPSSPHE---------------------- 1478
                     +P I + + D    L P +T      P +                      
Sbjct: 1144 TVVPDSAQAQPAILVDVPDSSPMLEPEHTPVAQEPPKDGKPKDPRKPSRRSTKRRKRTIA 1203

Query: 1479 ----EEFIDWWSKFFASI-------------------------------GEREKCGSYLE 1503
                E  IDWWSK++AS+                               G ++K    L+
Sbjct: 1204 DESAENVIDWWSKYYASLKKAQKAKERNPKGKKGNTEAKPDEVVVDIEDGPKKKKDKMLK 1263

Query: 1504 K--------DFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEET---EDPSVIGEF 1552
            K        +   L++YD  LE+   F    D+  TF+L+RGK+ E+    +   VIG+F
Sbjct: 1264 KKPKDDGIPNLAILQIYDGDLES--EFNNFEDWVKTFELFRGKSTEDDHGLDGDRVIGKF 1321

Query: 1553 KGLFKIYPLPEDPAIPMPPRQFHQ--LAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYI 1610
            KG F IY  P+D +     +   Q  +    P   L+R+YIV AF L P DP+GK DPYI
Sbjct: 1322 KGSFCIYKSPQDSSSEDSGQLRIQQGIPPNHPVTVLIRVYIVAAFNLSPADPDGKSDPYI 1381

Query: 1611 KISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETV 1670
             I +GK  + D+D YIP  L PVFG+ FE+  T P E  L I +YD+D++  D+ IGET 
Sbjct: 1382 VIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSILIYDHDMIGTDDLIGETK 1441

Query: 1671 VDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMF 1730
            +DLENR  SK  A CGL   Y + G N WRD  +P+++L   C+ +++  P +   ++  
Sbjct: 1442 IDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYFHPGKIQI 1501

Query: 1731 QDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPLQ 1782
             ++ +S + I      +  +   E  LAL VL            LVPEH+E+RPLY   +
Sbjct: 1502 GNQVFSGKTIFTEEDTDETVESYEH-LALKVLHSWEDIPEVGCRLVPEHIETRPLYHKDK 1560

Query: 1783 PDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSL-TGEK 1841
            P +EQG+LQMWVD+FPK + +PGPP +I+PRR + + LR  IWNT DVIL+D ++ TG+K
Sbjct: 1561 PGMEQGRLQMWVDMFPKDMPQPGPPVDISPRRPKGYELRVTIWNTEDVILEDENIFTGQK 1620

Query: 1842 MSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWR 1901
             SDIYVKGW+ G E+ KQ+TDVHY SL GEGNFNWRF+FPF YLPAE+   I K++  + 
Sbjct: 1621 SSDIYVKGWLKGLEDDKQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVITKRENIFS 1680

Query: 1902 LDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPE 1961
            L+K E K PA +V Q+WD ++ S DDFLG+L+++LN  P+ AK+AK C L + ++A   E
Sbjct: 1681 LEKMECKTPAVLVLQVWDFERLSSDDFLGTLEMNLNSFPRAAKSAKACDLAKFENA-SEE 1739

Query: 1962 WFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPK 2021
              +S+F+QK V+GWWP      + K L GK+E    +V   E E+ P G+ R EP     
Sbjct: 1740 TKISIFQQKRVRGWWPF----SKSKELTGKVEAEFHLVTAEEAEKNPVGKARKEPE---P 1792

Query: 2022 LEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMK 2081
            L  P RPDTSF WF SP+K + +++W+ ++  II+  IL IL++FL +FIY  P   + +
Sbjct: 1793 LAKPNRPDTSFSWFMSPFKCLYYLIWKNYKKYIIIAFILIILIIFLVLFIYTLPGAISRR 1852

Query: 2082 LV 2083
            +V
Sbjct: 1853 IV 1854



 Score =  348 bits (893), Expect = 3e-95
 Identities = 236/724 (32%), Positives = 372/724 (51%), Gaps = 112/724 (15%)

Query: 216 KPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNETLFFNLFDSP 274
           + Q++QI + + E RQL G NI PVV +    + K++ + +G NSP +NE   F+     
Sbjct: 79  RSQNYQIAITITEARQLVGENIDPVVTIEIGDEKKQSTVKEGTNSPFYNEYFVFDFIGPQ 138

Query: 275 GELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGAR 334
             LFD+ I I+V   + + +  L+G F++D+GT+Y +P H +  KW LL+DP D   G +
Sbjct: 139 VHLFDKIIKISVFHHKLIGS-VLIGSFKVDLGTVYNQPGHQFCNKWALLTDPGDIRTGTK 197

Query: 335 GYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALR--GAHFCLKVFRAEDLP 392
           GYLK  + V+G GD      K  S+ +E IE NLL P G  L    A F +++++AE LP
Sbjct: 198 GYLKCDISVMGKGDVLKTSPK-TSDTEEPIEKNLLIPNGFPLERPWARFYVRLYKAEGLP 256

Query: 393 QMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMF 452
           +M+ ++M NV +   F  + K+LVDPFVEVSFAG+M  + + +  A+P W++ +    MF
Sbjct: 257 KMNSSIMANVTK--AFVGDSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEMF 314

Query: 453 PSMCEKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEVDDYLGFLPTFGPCYINL 511
           P +C +++I++  WD  + ND+ +AT ++ + KIS      E D   GFLPTFGP +INL
Sbjct: 315 PPLCRRVKIQV--WDEGSMNDVALATHFIDLKKISN-----EQDGDKGFLPTFGPAWINL 367

Query: 512 YGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQ--------KVEDLPA 563
           YGSPR  +   D Y E+N G GEGV++RGR+L+ +  +++    Q        K   LP+
Sbjct: 368 YGSPRNHS-LMDDYQEMNEGFGEGVSFRGRILVEIAVEILSGRAQESKFSKALKELKLPS 426

Query: 564 DD------------------------------ILRVEKY--------LRRRKYSLFAAFY 585
            D                               + VE +         +  ++ LF AF+
Sbjct: 427 KDKDSKSSKGKDKADKTEDGKSQQASNKTNSTEVEVESFDVPPEIVPEKNEEFLLFGAFF 486

Query: 586 SATMLQDV--DDAIQFEVSIGNYGNKFD-------------------------------M 612
            ATM+     D  I FEVSIGN+GN  D                                
Sbjct: 487 EATMIDRKIGDKPISFEVSIGNFGNLIDGGSHHGSKKSAESAEEDLLPLLHEGQGDVAHD 546

Query: 613 TCLPLASTTQYSRAVF--DGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADR 670
             +P+ASTT   + +      +Y YLP+   KP V   S W D + R+   N L  +AD 
Sbjct: 547 VPIPMASTTHPEKPLVTEGNRNYNYLPFEAKKPCVYFISSWGDQTFRLHWSNMLEKMADF 606

Query: 671 LEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETP---SATHLDQYLY 727
           LE  +E+V   +K   S E  +  +  +  + I+  S  + +  + P   + T LD+   
Sbjct: 607 LEESIEEVRELIK--ISQEAPEEKMKTVLSDFISRSSAFISEAEKKPKMLNQTTLDKKRL 664

Query: 728 QLRTHHLSQITEAALAL------KLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVI 781
            L    L  + + A  +      KL   E+   + +A++++ ++R L +EPQ+++PD+ I
Sbjct: 665 TLCWQELEAMCKEAKGIIQQQKKKLSVDEM---IHEAQNFVEKIRFLVDEPQHTIPDVFI 721

Query: 782 WMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVK 841
           WML  ++RVAY R+ +  +L+S   A   GK+CGK++T FLK P ++  G  +  ++ V 
Sbjct: 722 WMLSNNRRVAYARIASKDLLYS-PVAGQMGKHCGKIKTHFLKPPGKRPAGWSVQAKVDVY 780

Query: 842 LWFG 845
           LW G
Sbjct: 781 LWLG 784



 Score = 41.2 bits (95), Expect = 0.011
 Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 6/91 (6%)

Query: 1    MLRVFILYAENVHTPDTD-ISDAYCSAVFAG--VKKRTKVIKNSVNPVWNEGFEWDLKGI 57
            ++RV+I+ A N+   D D  SD Y         +K R K I   +NPV+   FE      
Sbjct: 1357 LIRVYIVAAFNLSPADPDGKSDPYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQAT-- 1414

Query: 58   PLDQGSELHVVVKDHETMGRNRFLGEAKVPL 88
               + S L +++ DH+ +G +  +GE K+ L
Sbjct: 1415 -FPKESLLSILIYDHDMIGTDDLIGETKIDL 1444



 Score = 35.8 bits (81), Expect = 0.45
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 1154 DKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1194
            D     DP+  VSF  Q  +T V KN  +P W + +IF E+
Sbjct: 273  DSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEM 313



 Score = 34.3 bits (77), Expect = 1.3
 Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 8/93 (8%)

Query: 410 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ-----NITLPAMFPSMCEKMRIRII 464
           ++   L DPF +V+F      +KI+ +T +P WNQ     ++ L      + E   + ++
Sbjct: 841 ADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQMLLFNDLVLHGDVKELAESPPLVVV 900

Query: 465 DWDRLTHNDIVATTYLSMSKISAPGGEIEVDDY 497
           +   L  +D V       + ++AP  ++   DY
Sbjct: 901 E---LYDSDAVGKPEYLGATVAAPVVKLADQDY 930



 Score = 32.0 bits (71), Expect = 6.5
 Identities = 14/31 (45%), Positives = 18/31 (58%)

Query: 18  DISDAYCSAVFAGVKKRTKVIKNSVNPVWNE 48
           D+ D +    FAG   RT V KN  +PVW+E
Sbjct: 276 DLVDPFVEVSFAGQMGRTTVQKNCADPVWHE 306


>gi|35493860 otoferlin isoform d [Homo sapiens]
          Length = 1230

 Score =  719 bits (1856), Expect = 0.0
 Identities = 407/1057 (38%), Positives = 589/1057 (55%), Gaps = 128/1057 (12%)

Query: 1126 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1185
            P +S ++     + LR +MYQAR L A D    SDP+A V F++QSQ T V+  TL PTW
Sbjct: 201  PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260

Query: 1186 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1238
            DQ L+F  +E++GE   + + PP IV+E+YD D+ G  +FMGR   +P ++         
Sbjct: 261  DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320

Query: 1239 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1295
               P+L ++ + RG+  +G+LLA+FEL+Q                    +  +   DLP 
Sbjct: 321  RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360

Query: 1296 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1352
               P       I  VP  I+P L +  +E+L WGLR++K   LA +  P + +EC G+ V
Sbjct: 361  INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420

Query: 1353 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1412
            QS +I N +KNPNF+    + EV LP  EL  PP+ ++V+D R FGR  +VG   + SL 
Sbjct: 421  QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480

Query: 1413 SFLCDPYSAESPSPQGGPDDVSLLSPGEDV-----LIDID-DKEPLIPIQLADGLSSLAP 1466
             F+  P    +PS     + V  + P   +     ++ +D   E ++ + +A+       
Sbjct: 481  RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540

Query: 1467 TNTAS---PPSSPHEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1505
                +   P     +E  +DWWSK+FASI        ++E  G  LE+            
Sbjct: 541  KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600

Query: 1506 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1528
                                                  D LKVY  +LE+   F+   D+
Sbjct: 601  SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658

Query: 1529 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1578
             +TF L RGKT ++    TE+  ++G FKG   +Y  PLPED +           F  + 
Sbjct: 659  LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718

Query: 1579 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1638
            +  P   LVR+Y+VRA  L P D NGK DPYI I +GK  + D++NYI   L PVFGK F
Sbjct: 719  SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778

Query: 1639 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1698
            ++  + P+E  L + +YD+DL+  D+ IGET +DLENR  SK  A CG+ QTY   G N 
Sbjct: 779  DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838

Query: 1699 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1756
            WRD ++PSQ+L   C+  +V  P +    RV   ++ ++   EIE     N    P +E 
Sbjct: 839  WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895

Query: 1757 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1808
            +AL  L+           LVPEHVE+RPL +P +P IEQG+L++WVD+FP  +  PG P 
Sbjct: 896  VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955

Query: 1809 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1867
            +I+PR+ +++ LR IIWNT +V+L DD   TGEK SDI+V+GW+ G +E KQ TDVHY S
Sbjct: 956  DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015

Query: 1868 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1927
            L GEGNFNWR++FPFDYL AE+   I+KK++ +  D+TE KIPAR+  QIWD D FS DD
Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075

Query: 1928 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 1986
            FLG+++LDLNR P+ AKTAK+C+++           VS+F+QK VKGWWP +A  E ++ 
Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134

Query: 1987 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2046
             L GK+E  L ++   E E+ P G  R+EP+    LE P RPDT+F+WF +P K++K+++
Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTAFVWFLNPLKSIKYLI 1191

Query: 2047 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2083
              R++W II  ++  + LL L +F+Y+ P Y   KL+
Sbjct: 1192 CTRYKWLIIKIVLALLGLLMLGLFLYSLPGYMVKKLL 1228



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%)

Query: 700 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 754
           +EL  GC +   L D  +  S+ T LD+   +     L  + + A  L+  +    +   
Sbjct: 18  EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77

Query: 755 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 814
           L   +++L +LR LA+EPQ+S+PDI IWM+  +KRVAY RVP+  +LFS       GK+C
Sbjct: 78  LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136

Query: 815 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 853
            K++T+FLK P ++  G A   VQ +V+  LW GLS   KEF
Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178



 Score = 33.9 bits (76), Expect = 1.7
 Identities = 13/37 (35%), Positives = 21/37 (56%)

Query: 408 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 444
           F ++   L DPF  V F  +  C+++L +T  P W+Q
Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262


>gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens]
          Length = 802

 Score =  711 bits (1836), Expect = 0.0
 Identities = 369/764 (48%), Positives = 498/764 (65%), Gaps = 47/764 (6%)

Query: 1339 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1396
            SSP L+VE G +++++  IR+ + NPNF      L + V++P EE Y  P+ VKV+DN  
Sbjct: 5    SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64

Query: 1397 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ 1456
            FG++ V GQ  I  L+ + CDP++ +   P+               L  + +K+      
Sbjct: 65   FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK---------------LPTLSEKKH----- 104

Query: 1457 LADGLSSLAPTNTASPPSSPHEEEF---IDWWSKFFASIGEREKCGSYLEKDFDTLKVYD 1513
              D L  L         SS  E+E+   +DWWSK F +  E +    Y  KD+ TLKVY+
Sbjct: 105  -QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYE 160

Query: 1514 TQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQ 1573
             +LE V AF+GL DFC TFKLY+   ++   D  V+GEFKGLF+IYP PE+P  P PP Q
Sbjct: 161  CELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQ 217

Query: 1574 FHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1631
            F     +   PQ CLVR+Y+VRA  LQP+D NG CDPY+ + +GK  + ++D Y P TL+
Sbjct: 218  FLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLD 277

Query: 1632 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1691
            P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++Y
Sbjct: 278  PIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSY 337

Query: 1692 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH 1749
            C SGP +WRDQ+ PS LL  + ++  +  P++    D V +  K++ ++  E  + P  H
Sbjct: 338  CQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVH 396

Query: 1750 -LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1808
             LGP +ERLAL++L  QGLVPEHVE+R LYS  QP I+QGK+QMWVD+FPK LG PGP  
Sbjct: 397  GLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQV 456

Query: 1809 NITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSL 1868
            NI PR+ +R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+  QKTD+HY SL
Sbjct: 457  NINPRKPKRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSL 516

Query: 1869 GGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDF 1928
             GE +FNWRFIF  DYL AE+ C  ++KD  W LD T  K PAR++ Q+WDND FS DDF
Sbjct: 517  TGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDF 576

Query: 1929 LGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAE 1981
            LG L+LDL+ MP PA+ AK+CS+  +D    P+W         SLF++KTV GWWPC   
Sbjct: 577  LGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVL 634

Query: 1982 EGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKT 2041
            +G K  L+GK++M+LEI++E E   +PAG+G+ EPN  P L  P R +TSF W  SP + 
Sbjct: 635  DGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQN 694

Query: 2042 MKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2085
              +I W+R+R+ +I F+++ I+ L L  FIY+ P+Y AM  +KP
Sbjct: 695  FCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 738


>gi|4759026 RAS protein activator like 1 [Homo sapiens]
          Length = 804

 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 13/127 (10%)

Query: 1140 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1199
            LRC++  ARDLA  D    SDP+A V +  QS +T  +K T  P WD+ L         E
Sbjct: 135  LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVL---------E 185

Query: 1200 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQP-SLERMPRLAWF---PLTRGSQPSGE 1255
               +   P  + VEL+D D  G ++F+G     P +L++ P   WF   P  R  + SG 
Sbjct: 186  LREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAEEDSGG 245

Query: 1256 LLASFEL 1262
             L +  +
Sbjct: 246  NLGALRV 252



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 50/209 (23%), Positives = 90/209 (43%), Gaps = 20/209 (9%)

Query: 1466 PTNTASPPSSPH-----EEEFIDWWSKFFASIGE--REKCGSYLEKDFDTLKVYDTQLEN 1518
            P    S  S P+     ++E +   +  + S+G    E+   +L  DF  L  Y    + 
Sbjct: 18   PAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVHLPLDFHQLAFYVLDEDT 77

Query: 1519 VEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLA 1578
            V    G  D      L R   +  T DP  I  +  L ++ P   D  +        Q+ 
Sbjct: 78   V----GHDDIIGKISLSR---EAITADPRGIDSWINLSRVDP---DAEVQGEICLSVQML 127

Query: 1579 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1638
              G   CL R +++ A  L P+D +G  DP+ ++  G +S+  + + I  T  P + ++ 
Sbjct: 128  EDGQGRCL-RCHVLHARDLAPRDISGTSDPFARVFWGSQSL--ETSTIKKTRFPHWDEVL 184

Query: 1639 ELTCTLPLEKDLKITLYDYDLLSKDEKIG 1667
            EL         L++ L+D+D++ K++ +G
Sbjct: 185  ELREMPGAPSPLRVELWDWDMVGKNDFLG 213



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 59/268 (22%), Positives = 100/268 (37%), Gaps = 64/268 (23%)

Query: 222 IRVQVIEGRQLPGVNIKP------VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPG 275
           + V+V+EGR LP  ++        +VKV      +   + +   P + E    +L     
Sbjct: 7   LNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVHL----- 61

Query: 276 ELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLS--DPDDFSAGA 333
            L    +   V+D  ++  D ++G+  +    I  +PR   +  W+ LS  DPD   A  
Sbjct: 62  PLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRG--IDSWINLSRVDPD---AEV 116

Query: 334 RGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQ 393
           +G +  S+ +L                 ED +   LR              V  A DL  
Sbjct: 117 QGEICLSVQML-----------------EDGQGRCLR------------CHVLHARDLAP 147

Query: 394 MDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFP 453
            D +                   DPF  V +  + L +  ++KT  P W++ + L  M P
Sbjct: 148 RDIS----------------GTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREM-P 190

Query: 454 SMCEKMRIRIIDWDRLTHNDIVATTYLS 481
                +R+ + DWD +  ND +     S
Sbjct: 191 GAPSPLRVELWDWDMVGKNDFLGMVEFS 218



 Score = 33.9 bits (76), Expect = 1.7
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 6/83 (7%)

Query: 2   LRVFILYAENVHTPD-TDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEW-DLKGIPL 59
           LR  +L+A ++   D +  SD +    +      T  IK +  P W+E  E  ++ G P 
Sbjct: 135 LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGAP- 193

Query: 60  DQGSELHVVVKDHETMGRNRFLG 82
              S L V + D + +G+N FLG
Sbjct: 194 ---SPLRVELWDWDMVGKNDFLG 213


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%)

Query: 1113 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1157
            S SVS    G ++PT               +   +D GN   L  ++ QAR+L   D + 
Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726

Query: 1158 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1203
            +SDP+  V  L    + +VV+N              +LNP W+QT+I+  I +       
Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780

Query: 1204 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1257
              +  ++ V ++D+D + +++F+G  +   S    L+  PR  W+PL   ++    G+  
Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838

Query: 1258 ASFELIQREKPAI 1270
            +S    Q  KP++
Sbjct: 4839 SSQSSQQSPKPSV 4851



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%)

Query: 1589 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1636
            I+I++A  L P+D NG  DP++K+ +  G+  V    N          ++  +L P + +
Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770

Query: 1637 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1675
                  ++     +K L++T++DYD  S ++ +GE ++DL +
Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812



 Score = 39.3 bits (90), Expect = 0.041
 Identities = 40/130 (30%), Positives = 57/130 (43%), Gaps = 21/130 (16%)

Query: 29   AGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKV 86
            A  K+RTK ++ S+NP WN+   +  K I ++Q     L V V D++    N FLGE  +
Sbjct: 4751 AEYKRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLI 4808

Query: 87   PLREVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPP 135
             L       S S   N P     K+ T     G S   Q S  +P P  +      +FP 
Sbjct: 4809 DL------SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPD 4862

Query: 136  PTPLEPSPTL 145
            P+     PT+
Sbjct: 4863 PSKDMQVPTI 4872



 Score = 36.6 bits (83), Expect = 0.26
 Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%)

Query: 431  SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 486
            +K ++K+ NP+WNQ +   ++     +K  + + + D+DR + ND +    + +S  S
Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814



 Score = 32.0 bits (71), Expect = 6.5
 Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 12/123 (9%)

Query: 111 QPTGASLVLQVSYTPLPGAV--PLFPPPTPLEPSPTL-PDLDVVADTGGEEDTEDQGLTG 167
           QP+G +  L       PG V  P+ PP T   P+  L P       TG E+ + +Q    
Sbjct: 334 QPSGLTKPLAQQ----PGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389

Query: 168 DEAEP-----FLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQI 222
             A+P        Q  GP  P T +    +P    PG++    AP   K    +P   +I
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449

Query: 223 RVQ 225
             Q
Sbjct: 450 PAQ 452



 Score = 32.0 bits (71), Expect = 6.5
 Identities = 46/160 (28%), Positives = 56/160 (35%), Gaps = 39/160 (24%)

Query: 81  LGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPP----- 135
           LG AK P ++   T S   S   P      QP G      V  TP     P  PP     
Sbjct: 366 LGPAKPPAQQ---TGSEKPSSEQPGPKALAQPPG------VGKTPAQQPGPAKPPTQQVG 416

Query: 136 -PTPLE-----------PSPTLPDLD------VVADTGGEEDTEDQGLTGDEAEPFLDQS 177
            P PL            P PT   +       + A   G   T  Q  TG    P   Q 
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ-TGPTKPP--SQL 473

Query: 178 GGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKP 217
            GP  P   +  P++PPP  PG     + P S++  S KP
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPG----SAKPPSQQPGSTKP 509


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%)

Query: 1113 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1157
            S SVS    G ++PT               +   +D GN   L  ++ QAR+L   D + 
Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726

Query: 1158 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1203
            +SDP+  V  L    + +VV+N              +LNP W+QT+I+  I +       
Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780

Query: 1204 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1257
              +  ++ V ++D+D + +++F+G  +   S    L+  PR  W+PL   ++    G+  
Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838

Query: 1258 ASFELIQREKPAI 1270
            +S    Q  KP++
Sbjct: 4839 SSQSSQQSPKPSV 4851



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%)

Query: 1589 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1636
            I+I++A  L P+D NG  DP++K+ +  G+  V    N          ++  +L P + +
Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770

Query: 1637 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1675
                  ++     +K L++T++DYD  S ++ +GE ++DL +
Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812



 Score = 39.3 bits (90), Expect = 0.041
 Identities = 40/130 (30%), Positives = 57/130 (43%), Gaps = 21/130 (16%)

Query: 29   AGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKV 86
            A  K+RTK ++ S+NP WN+   +  K I ++Q     L V V D++    N FLGE  +
Sbjct: 4751 AEYKRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLI 4808

Query: 87   PLREVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPP 135
             L       S S   N P     K+ T     G S   Q S  +P P  +      +FP 
Sbjct: 4809 DL------SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPD 4862

Query: 136  PTPLEPSPTL 145
            P+     PT+
Sbjct: 4863 PSKDMQVPTI 4872



 Score = 36.6 bits (83), Expect = 0.26
 Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%)

Query: 431  SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 486
            +K ++K+ NP+WNQ +   ++     +K  + + + D+DR + ND +    + +S  S
Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814



 Score = 32.0 bits (71), Expect = 6.5
 Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 12/123 (9%)

Query: 111 QPTGASLVLQVSYTPLPGAV--PLFPPPTPLEPSPTL-PDLDVVADTGGEEDTEDQGLTG 167
           QP+G +  L       PG V  P+ PP T   P+  L P       TG E+ + +Q    
Sbjct: 334 QPSGLTKPLAQQ----PGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389

Query: 168 DEAEP-----FLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQI 222
             A+P        Q  GP  P T +    +P    PG++    AP   K    +P   +I
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449

Query: 223 RVQ 225
             Q
Sbjct: 450 PAQ 452



 Score = 32.0 bits (71), Expect = 6.5
 Identities = 46/160 (28%), Positives = 56/160 (35%), Gaps = 39/160 (24%)

Query: 81  LGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPP----- 135
           LG AK P ++   T S   S   P      QP G      V  TP     P  PP     
Sbjct: 366 LGPAKPPAQQ---TGSEKPSSEQPGPKALAQPPG------VGKTPAQQPGPAKPPTQQVG 416

Query: 136 -PTPLE-----------PSPTLPDLD------VVADTGGEEDTEDQGLTGDEAEPFLDQS 177
            P PL            P PT   +       + A   G   T  Q  TG    P   Q 
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ-TGPTKPP--SQL 473

Query: 178 GGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKP 217
            GP  P   +  P++PPP  PG     + P S++  S KP
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPG----SAKPPSQQPGSTKP 509


>gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo
            sapiens]
          Length = 778

 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)

Query: 1144 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1203
            + + RDL AMD +  SDPY      HQ  K+ ++  TLNP W +   F+  E        
Sbjct: 255  LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 306

Query: 1204 AEQPPSIVVELYDHDTYGADEFMGRC 1229
             E+   I +  +D D    D+F+GRC
Sbjct: 307  -ERGGVIDITAWDKDAGKRDDFIGRC 331



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 1586 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1645
            +V I ++    L+  D NG  DPY+K  +G +    +   +P TL P + + F+      
Sbjct: 250  IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 307

Query: 1646 LEKDLKITLYDYDLLSKDEKIGETVVDL 1673
                + IT +D D   +D+ IG   VDL
Sbjct: 308  RGGVIDITAWDKDAGKRDDFIGRCQVDL 335



 Score = 41.2 bits (95), Expect = 0.011
 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)

Query: 1589 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1646
            I + R   L  +D  G  DPY+K  IG K V  +   I   L PV+    E  C L   L
Sbjct: 44   ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 99

Query: 1647 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1680
             + L I ++DYD   +D+ +G   +DL    L++
Sbjct: 100  REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 133



 Score = 40.8 bits (94), Expect = 0.014
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 5/91 (5%)

Query: 2   LRVFILYAENVHTPD-TDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
           L+V ++ AE +   D T  SD +C       +  T  +  ++NP WN+ F +++K    D
Sbjct: 407 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----D 462

Query: 61  QGSELHVVVKDHETMGRNRFLGEAKVPLREV 91
             S L V V D +      FLG+  +PL  +
Sbjct: 463 IHSVLEVTVYDEDRDRSADFLGKVAIPLLSI 493



 Score = 38.9 bits (89), Expect = 0.053
 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%)

Query: 1570 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1629
            P R FH L   G     +++ ++RA GL   D  GK DP+  + +    +     Y    
Sbjct: 394  PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 447

Query: 1630 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1673
            L P + K+F       +   L++T+YD D     + +G+  + L
Sbjct: 448  LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 490



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 417 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 475
           DP+V+    GK +  SKI+ K  NP W +   +  +   + E + I++ D+D    +D +
Sbjct: 62  DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 119

Query: 476 ATTYLSMSKI 485
            + +L ++++
Sbjct: 120 GSAFLDLTQL 129



 Score = 35.0 bits (79), Expect = 0.77
 Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 3/70 (4%)

Query: 19  ISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRN 78
           +SD Y        K ++K++  ++NP W E F++ L     ++G  + +   D +   R+
Sbjct: 269 LSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGVIDITAWDKDAGKRD 325

Query: 79  RFLGEAKVPL 88
            F+G  +V L
Sbjct: 326 DFIGRCQVDL 335



 Score = 35.0 bits (79), Expect = 0.77
 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%)

Query: 1140 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1199
            L+  + +A  L A D    SDP+ +V   +    T  V   LNP W++   F        
Sbjct: 407  LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 458

Query: 1200 PATVAEQPPSIVVELYDHDTYGADEFMGR 1228
               + +    + V +YD D   + +F+G+
Sbjct: 459  --NIKDIHSVLEVTVYDEDRDRSADFLGK 485



 Score = 34.3 bits (77), Expect = 1.3
 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%)

Query: 1138 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1194
            Y L   + + + LAA D+   SDPY  V F     +  ++ ++   LNP W++      +
Sbjct: 40   YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 96

Query: 1195 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1227
            +   EP         + ++++D+D    D+FMG
Sbjct: 97   DHLREP---------LYIKVFDYDFGLQDDFMG 120



 Score = 32.0 bits (71), Expect = 6.5
 Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%)

Query: 411 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 470
           +   L DP+V+     +   SKI+ KT NPQW +      ++      + I   D D   
Sbjct: 265 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 323

Query: 471 HNDIVATTYLSMSKIS 486
            +D +    + +S +S
Sbjct: 324 RDDFIGRCQVDLSALS 339


>gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo
            sapiens]
          Length = 999

 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)

Query: 1144 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1203
            + + RDL AMD +  SDPY      HQ  K+ ++  TLNP W +   F+  E        
Sbjct: 476  LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 527

Query: 1204 AEQPPSIVVELYDHDTYGADEFMGRC 1229
             E+   I +  +D D    D+F+GRC
Sbjct: 528  -ERGGVIDITAWDKDAGKRDDFIGRC 552



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 1586 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1645
            +V I ++    L+  D NG  DPY+K  +G +    +   +P TL P + + F+      
Sbjct: 471  IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 528

Query: 1646 LEKDLKITLYDYDLLSKDEKIGETVVDL 1673
                + IT +D D   +D+ IG   VDL
Sbjct: 529  RGGVIDITAWDKDAGKRDDFIGRCQVDL 556



 Score = 41.2 bits (95), Expect = 0.011
 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)

Query: 1589 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1646
            I + R   L  +D  G  DPY+K  IG K V  +   I   L PV+    E  C L   L
Sbjct: 265  ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 320

Query: 1647 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1680
             + L I ++DYD   +D+ +G   +DL    L++
Sbjct: 321  REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 354



 Score = 40.8 bits (94), Expect = 0.014
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 5/91 (5%)

Query: 2   LRVFILYAENVHTPD-TDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
           L+V ++ AE +   D T  SD +C       +  T  +  ++NP WN+ F +++K    D
Sbjct: 628 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----D 683

Query: 61  QGSELHVVVKDHETMGRNRFLGEAKVPLREV 91
             S L V V D +      FLG+  +PL  +
Sbjct: 684 IHSVLEVTVYDEDRDRSADFLGKVAIPLLSI 714



 Score = 38.9 bits (89), Expect = 0.053
 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%)

Query: 1570 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1629
            P R FH L   G     +++ ++RA GL   D  GK DP+  + +    +     Y    
Sbjct: 615  PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 668

Query: 1630 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1673
            L P + K+F       +   L++T+YD D     + +G+  + L
Sbjct: 669  LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 711



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 417 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 475
           DP+V+    GK +  SKI+ K  NP W +   +  +   + E + I++ D+D    +D +
Sbjct: 283 DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 340

Query: 476 ATTYLSMSKI 485
            + +L ++++
Sbjct: 341 GSAFLDLTQL 350



 Score = 35.0 bits (79), Expect = 0.77
 Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 3/70 (4%)

Query: 19  ISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRN 78
           +SD Y        K ++K++  ++NP W E F++ L     ++G  + +   D +   R+
Sbjct: 490 LSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGVIDITAWDKDAGKRD 546

Query: 79  RFLGEAKVPL 88
            F+G  +V L
Sbjct: 547 DFIGRCQVDL 556



 Score = 35.0 bits (79), Expect = 0.77
 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%)

Query: 1140 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1199
            L+  + +A  L A D    SDP+ +V   +    T  V   LNP W++   F        
Sbjct: 628  LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 679

Query: 1200 PATVAEQPPSIVVELYDHDTYGADEFMGR 1228
               + +    + V +YD D   + +F+G+
Sbjct: 680  --NIKDIHSVLEVTVYDEDRDRSADFLGK 706



 Score = 34.3 bits (77), Expect = 1.3
 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%)

Query: 1138 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1194
            Y L   + + + LAA D+   SDPY  V F     +  ++ ++   LNP W++      +
Sbjct: 261  YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 317

Query: 1195 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1227
            +   EP         + ++++D+D    D+FMG
Sbjct: 318  DHLREP---------LYIKVFDYDFGLQDDFMG 341



 Score = 32.0 bits (71), Expect = 6.5
 Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%)

Query: 411 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 470
           +   L DP+V+     +   SKI+ KT NPQW +      ++      + I   D D   
Sbjct: 486 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 544

Query: 471 HNDIVATTYLSMSKIS 486
            +D +    + +S +S
Sbjct: 545 RDDFIGRCQVDLSALS 560


>gi|239743309 PREDICTED: similar to calcium-promoted Ras inactivator
            isoform 2 [Homo sapiens]
          Length = 731

 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 11/109 (10%)

Query: 1140 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1199
            LRC + +ARDLA  D++  SDP+  V +  ++++T +VK +  P W++T   +E E+  E
Sbjct: 63   LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET---FEFEL-QE 118

Query: 1200 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRL--AWFPL 1246
             A  A     + VE +D D    ++F+G+ +      R+ +    WF L
Sbjct: 119  GAMEA-----LCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRL 162



 Score = 48.5 bits (114), Expect = 7e-05
 Identities = 24/94 (25%), Positives = 52/94 (55%), Gaps = 2/94 (2%)

Query: 1581 GPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFEL 1640
            G + C +R  ++ A  L PKD NG  DP++++    K  + + + +  +  P + + FE 
Sbjct: 57   GARACRLRCSVLEARDLAPKDRNGTSDPFVRVRY--KGRTRETSIVKKSCYPRWNETFEF 114

Query: 1641 TCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLE 1674
                   + L +  +D+DL+S+++ +G+ V+D++
Sbjct: 115  ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQ 148



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 31/136 (22%), Positives = 53/136 (38%), Gaps = 18/136 (13%)

Query: 350 APLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFE 409
           A L   DP E+ +  E +L        R       V  A DL   D              
Sbjct: 33  AHLTEVDPDEEVQG-EIHLRLEVWPGARACRLRCSVLEARDLAPKD-------------- 77

Query: 410 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRL 469
             +    DPFV V + G+   + I++K+  P+WN+         +M E + +   DWD +
Sbjct: 78  --RNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAM-EALCVEAWDWDLV 134

Query: 470 THNDIVATTYLSMSKI 485
           + ND +    + + ++
Sbjct: 135 SRNDFLGKVVIDVQRL 150



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 4/91 (4%)

Query: 2   LRVFILYAENVHTPDTD-ISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
           LR  +L A ++   D +  SD +    + G  + T ++K S  P WNE FE++L+   ++
Sbjct: 63  LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAME 122

Query: 61  QGSELHVVVKDHETMGRNRFLGEAKVPLREV 91
               L V   D + + RN FLG+  + ++ +
Sbjct: 123 ---ALCVEAWDWDLVSRNDFLGKVVIDVQRL 150


>gi|239743307 PREDICTED: similar to calcium-promoted Ras inactivator
            isoform 1 [Homo sapiens]
          Length = 757

 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 11/109 (10%)

Query: 1140 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1199
            LRC + +ARDLA  D++  SDP+  V +  ++++T +VK +  P W++T   +E E+  E
Sbjct: 135  LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET---FEFEL-QE 190

Query: 1200 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRL--AWFPL 1246
             A  A     + VE +D D    ++F+G+ +      R+ +    WF L
Sbjct: 191  GAMEA-----LCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRL 234



 Score = 48.5 bits (114), Expect = 7e-05
 Identities = 24/94 (25%), Positives = 52/94 (55%), Gaps = 2/94 (2%)

Query: 1581 GPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFEL 1640
            G + C +R  ++ A  L PKD NG  DP++++    K  + + + +  +  P + + FE 
Sbjct: 129  GARACRLRCSVLEARDLAPKDRNGTSDPFVRVRY--KGRTRETSIVKKSCYPRWNETFEF 186

Query: 1641 TCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLE 1674
                   + L +  +D+DL+S+++ +G+ V+D++
Sbjct: 187  ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQ 220



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 53/268 (19%), Positives = 96/268 (35%), Gaps = 60/268 (22%)

Query: 224 VQVIEGRQLPGVNIKP------VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGEL 277
           ++++EG+ LP  +I        +VKV      +   + K   P + E    +L  +    
Sbjct: 9   IRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPT---- 64

Query: 278 FDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYL 337
               +   V+D  +L  D ++G+  +   TI   P+                  G  G+ 
Sbjct: 65  -FHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPK------------------GFSGW- 104

Query: 338 KTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDA 397
                       A L   DP E+ +  E +L        R       V  A DL   D  
Sbjct: 105 ------------AHLTEVDPDEEVQG-EIHLRLEVWPGARACRLRCSVLEARDLAPKD-- 149

Query: 398 VMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCE 457
                         +    DPFV V + G+   + I++K+  P+WN+         +M E
Sbjct: 150 --------------RNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAM-E 194

Query: 458 KMRIRIIDWDRLTHNDIVATTYLSMSKI 485
            + +   DWD ++ ND +    + + ++
Sbjct: 195 ALCVEAWDWDLVSRNDFLGKVVIDVQRL 222



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 4/91 (4%)

Query: 2   LRVFILYAENVHTPDTD-ISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
           LR  +L A ++   D +  SD +    + G  + T ++K S  P WNE FE++L+   ++
Sbjct: 135 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAME 194

Query: 61  QGSELHVVVKDHETMGRNRFLGEAKVPLREV 91
               L V   D + + RN FLG+  + ++ +
Sbjct: 195 ---ALCVEAWDWDLVSRNDFLGKVVIDVQRL 222


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,702,184
Number of Sequences: 37866
Number of extensions: 4652834
Number of successful extensions: 16711
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 210
Number of HSP's that attempted gapping in prelim test: 14424
Number of HSP's gapped (non-prelim): 1729
length of query: 2087
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1969
effective length of database: 13,779,330
effective search space: 27131500770
effective search space used: 27131500770
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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