Guide to the Human Genome
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Search of human proteins with 194595501

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo
sapiens]
         (1052 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo sapi...  2078   0.0  
gi|47578111 hypothetical protein LOC140699 isoform 2 [Homo sapiens]  1196   0.0  
gi|47578113 hypothetical protein LOC140699 isoform 3 [Homo sapiens]  1106   0.0  
gi|223278410 hypothetical protein LOC374977 [Homo sapiens]            378   e-104
gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5...   223   6e-58
gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens]       223   6e-58
gi|148727311 hypothetical protein LOC389690 [Homo sapiens]            223   7e-58
gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]     158   3e-38
gi|154937380 hypothetical protein LOC642475 [Homo sapiens]            157   6e-38
gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]     154   4e-37
gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]     151   4e-36
gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]             142   2e-33
gi|117956387 hypothetical protein LOC80133 [Homo sapiens]              58   5e-08
gi|54112117 splicing factor 3b, subunit 1 isoform 1 [Homo sapiens]     38   0.057
gi|187761381 maestro isoform d [Homo sapiens]                          34   0.83 
gi|187761375 maestro isoform a [Homo sapiens]                          34   0.83 
gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ...    33   1.8  
gi|154277118 spectrin repeat containing, nuclear envelope 1 isof...    32   4.1  
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    32   4.1  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    32   4.1  
gi|156616294 peptidoglycan recognition protein 2 precursor [Homo...    32   4.1  
gi|239751877 PREDICTED: hypothetical protein XP_002348035 [Homo ...    31   5.4  
gi|28626504 fermitin family homolog 3 short form [Homo sapiens]        31   7.0  
gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]     31   7.0  
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               31   7.0  
gi|7662655 SBBI31 protein [Homo sapiens]                               31   7.0  
gi|153792074 proline rich 12 [Homo sapiens]                            31   7.0  
gi|76563908 hypothetical protein LOC169436 [Homo sapiens]              30   9.2  
gi|239746217 PREDICTED: zinc finger protein 66 [Homo sapiens]          30   9.2  
gi|188536004 zinc finger protein 469 [Homo sapiens]                    30   9.2  

>gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo sapiens]
          Length = 1052

 Score = 2078 bits (5384), Expect = 0.0
 Identities = 1052/1052 (100%), Positives = 1052/1052 (100%)

Query: 1    MPLSRRGRGSRLAGSRAATSNLPRATALSPKSAGRGALSISHAQLLTRRRHSSEQVPPES 60
            MPLSRRGRGSRLAGSRAATSNLPRATALSPKSAGRGALSISHAQLLTRRRHSSEQVPPES
Sbjct: 1    MPLSRRGRGSRLAGSRAATSNLPRATALSPKSAGRGALSISHAQLLTRRRHSSEQVPPES 60

Query: 61   EPRADFRSGKWLQEPATGDARDSRQALRARMSSKHRICSQEEVVIPCAYDSDSESVDLEL 120
            EPRADFRSGKWLQEPATGDARDSRQALRARMSSKHRICSQEEVVIPCAYDSDSESVDLEL
Sbjct: 61   EPRADFRSGKWLQEPATGDARDSRQALRARMSSKHRICSQEEVVIPCAYDSDSESVDLEL 120

Query: 121  SNLEIIKKGSSSIELTDLDIPDIPGLHCEPLSHSPRHLTQQDPLSEAIVEKLIQSIQKVF 180
            SNLEIIKKGSSSIELTDLDIPDIPGLHCEPLSHSPRHLTQQDPLSEAIVEKLIQSIQKVF
Sbjct: 121  SNLEIIKKGSSSIELTDLDIPDIPGLHCEPLSHSPRHLTQQDPLSEAIVEKLIQSIQKVF 180

Query: 181  NGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVLVQEERPHSLSSS 240
            NGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVLVQEERPHSLSSS
Sbjct: 181  NGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVLVQEERPHSLSSS 240

Query: 241  MRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNT 300
            MRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNT
Sbjct: 241  MRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNT 300

Query: 301  ECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVKDHERERATASMAQVLKC 360
            ECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVKDHERERATASMAQVLKC
Sbjct: 301  ECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVKDHERERATASMAQVLKC 360

Query: 361  LSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKK 420
            LSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKK
Sbjct: 361  LSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKK 420

Query: 421  DQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKTL 480
            DQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKTL
Sbjct: 421  DQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKTL 480

Query: 481  KHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFISR 540
            KHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFISR
Sbjct: 481  KHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFISR 540

Query: 541  PKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMA 600
            PKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMA
Sbjct: 541  PKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMA 600

Query: 601  YVAVAATDALYEVFLGNRLRAATFRLFPQLLMTLLIQIHHSIGLTMSDVDIPSGLYTEQE 660
            YVAVAATDALYEVFLGNRLRAATFRLFPQLLMTLLIQIHHSIGLTMSDVDIPSGLYTEQE
Sbjct: 601  YVAVAATDALYEVFLGNRLRAATFRLFPQLLMTLLIQIHHSIGLTMSDVDIPSGLYTEQE 660

Query: 661  VPSEVTPLCFAMQATKTLLLRTCCLQEFNIMEKNKGWALLGGKDGHLQGLFLLANALLER 720
            VPSEVTPLCFAMQATKTLLLRTCCLQEFNIMEKNKGWALLGGKDGHLQGLFLLANALLER
Sbjct: 661  VPSEVTPLCFAMQATKTLLLRTCCLQEFNIMEKNKGWALLGGKDGHLQGLFLLANALLER 720

Query: 721  NQLLAQKVMYLLVPLLNRGNDKHKLTSAGFFVELLRSPVAKRLPSIYSVARFKDWLQDGN 780
            NQLLAQKVMYLLVPLLNRGNDKHKLTSAGFFVELLRSPVAKRLPSIYSVARFKDWLQDGN
Sbjct: 721  NQLLAQKVMYLLVPLLNRGNDKHKLTSAGFFVELLRSPVAKRLPSIYSVARFKDWLQDGN 780

Query: 781  HLFRILGLRGLYNLVGHQEMREDIKSLLPYIVDSLRETDEKIVLSAIQILLQLVRTMDFT 840
            HLFRILGLRGLYNLVGHQEMREDIKSLLPYIVDSLRETDEKIVLSAIQILLQLVRTMDFT
Sbjct: 781  HLFRILGLRGLYNLVGHQEMREDIKSLLPYIVDSLRETDEKIVLSAIQILLQLVRTMDFT 840

Query: 841  TLAAMMRTLFSLFGDVRSDVHRFSVTLFGAAIKSVKNPDKKSIENQVLDSLVPLLLYSQD 900
            TLAAMMRTLFSLFGDVRSDVHRFSVTLFGAAIKSVKNPDKKSIENQVLDSLVPLLLYSQD
Sbjct: 841  TLAAMMRTLFSLFGDVRSDVHRFSVTLFGAAIKSVKNPDKKSIENQVLDSLVPLLLYSQD 900

Query: 901  ENDAVAEESRQVLTICAQFLKWKLPQEVYSKDPWHIKPTEAGTICRFFEKKCKGKINILE 960
            ENDAVAEESRQVLTICAQFLKWKLPQEVYSKDPWHIKPTEAGTICRFFEKKCKGKINILE
Sbjct: 901  ENDAVAEESRQVLTICAQFLKWKLPQEVYSKDPWHIKPTEAGTICRFFEKKCKGKINILE 960

Query: 961  QTLMYSKNPKLPIRRSAVLFVGLLSKYMDHNELRRMGTDWIEDDLRDLLCDPEPSLCIIA 1020
            QTLMYSKNPKLPIRRSAVLFVGLLSKYMDHNELRRMGTDWIEDDLRDLLCDPEPSLCIIA
Sbjct: 961  QTLMYSKNPKLPIRRSAVLFVGLLSKYMDHNELRRMGTDWIEDDLRDLLCDPEPSLCIIA 1020

Query: 1021 SQTLLLVQMARAEPKPKQRVNWLQKLMGRSSA 1052
            SQTLLLVQMARAEPKPKQRVNWLQKLMGRSSA
Sbjct: 1021 SQTLLLVQMARAEPKPKQRVNWLQKLMGRSSA 1052


>gi|47578111 hypothetical protein LOC140699 isoform 2 [Homo sapiens]
          Length = 608

 Score = 1196 bits (3094), Expect = 0.0
 Identities = 605/607 (99%), Positives = 606/607 (99%)

Query: 1   MPLSRRGRGSRLAGSRAATSNLPRATALSPKSAGRGALSISHAQLLTRRRHSSEQVPPES 60
           MPLSRRGRGSRLAGSRAATSNLPRATALSPKSAGRGALSISHAQLLTRRRHSSEQVPPES
Sbjct: 1   MPLSRRGRGSRLAGSRAATSNLPRATALSPKSAGRGALSISHAQLLTRRRHSSEQVPPES 60

Query: 61  EPRADFRSGKWLQEPATGDARDSRQALRARMSSKHRICSQEEVVIPCAYDSDSESVDLEL 120
           EPRADFRSGKWLQEPATGDARDSRQALRARMSSKHRICSQEEVVIPCAYDSDSESVDLEL
Sbjct: 61  EPRADFRSGKWLQEPATGDARDSRQALRARMSSKHRICSQEEVVIPCAYDSDSESVDLEL 120

Query: 121 SNLEIIKKGSSSIELTDLDIPDIPGLHCEPLSHSPRHLTQQDPLSEAIVEKLIQSIQKVF 180
           SNLEIIKKGSSSIELTDLDIPDIPGLHCEPLSHSPRHLTQQDPLSEAIVEKLIQSIQKVF
Sbjct: 121 SNLEIIKKGSSSIELTDLDIPDIPGLHCEPLSHSPRHLTQQDPLSEAIVEKLIQSIQKVF 180

Query: 181 NGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVLVQEERPHSLSSS 240
           NGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVLVQEERPHSLSSS
Sbjct: 181 NGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVLVQEERPHSLSSS 240

Query: 241 MRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNT 300
           MRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNT
Sbjct: 241 MRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNT 300

Query: 301 ECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVKDHERERATASMAQVLKC 360
           ECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVKDHERERATASMAQVLKC
Sbjct: 301 ECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVKDHERERATASMAQVLKC 360

Query: 361 LSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKK 420
           LSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKK
Sbjct: 361 LSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKK 420

Query: 421 DQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKTL 480
           DQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKTL
Sbjct: 421 DQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKTL 480

Query: 481 KHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFISR 540
           KHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFISR
Sbjct: 481 KHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFISR 540

Query: 541 PKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMA 600
           PKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMA
Sbjct: 541 PKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMA 600

Query: 601 YVAVAAT 607
           YVAVA +
Sbjct: 601 YVAVAVS 607


>gi|47578113 hypothetical protein LOC140699 isoform 3 [Homo sapiens]
          Length = 573

 Score = 1106 bits (2860), Expect = 0.0
 Identities = 569/607 (93%), Positives = 570/607 (93%), Gaps = 35/607 (5%)

Query: 1   MPLSRRGRGSRLAGSRAATSNLPRATALSPKSAGRGALSISHAQLLTRRRHSSEQVPPES 60
           MPLSRRGRGSRLAGSRAATSNLPRATALSPKSAGRGALSISHAQLLTRRRHSSEQVPPES
Sbjct: 1   MPLSRRGRGSRLAGSRAATSNLPRATALSPKSAGRGALSISHAQLLTRRRHSSEQVPPES 60

Query: 61  EPRADFRSGKWLQEPATGDARDSRQALRARMSSKHRICSQEEVVIPCAYDSDSESVDLEL 120
           EPRADFRSGKWLQEPATGDARDSRQALRARMSSKHRICSQEEVVIPCAYDSDSESVDLEL
Sbjct: 61  EPRADFRSGKWLQEPATGDARDSRQALRARMSSKHRICSQEEVVIPCAYDSDSESVDLEL 120

Query: 121 SNLEIIKKGSSSIELTDLDIPDIPGLHCEPLSHSPRHLTQQDPLSEAIVEKLIQSIQKVF 180
           SNLEIIKKGSSSIELTDLDIPDIPGLHCEPLSHSPRHLTQQDPLSEAIVEKLIQSIQKVF
Sbjct: 121 SNLEIIKKGSSSIELTDLDIPDIPGLHCEPLSHSPRHLTQQDPLSEAIVEKLIQSIQKVF 180

Query: 181 NGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVLVQEERPHSLSSS 240
           NGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVLVQEERPHSLSSS
Sbjct: 181 NGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVLVQEERPHSLSSS 240

Query: 241 MRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNT 300
           MRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNT
Sbjct: 241 MRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNT 300

Query: 301 ECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVKDHERERATASMAQVLKC 360
           ECLYRQTFQAFSEMLQSLVVKDPHLENLDTII                            
Sbjct: 301 ECLYRQTFQAFSEMLQSLVVKDPHLENLDTII---------------------------- 332

Query: 361 LSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKK 420
                  KLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKK
Sbjct: 333 -------KLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKK 385

Query: 421 DQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKTL 480
           DQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLK L
Sbjct: 386 DQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKNL 445

Query: 481 KHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFISR 540
           KHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFISR
Sbjct: 446 KHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFISR 505

Query: 541 PKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMA 600
           PKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMA
Sbjct: 506 PKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMA 565

Query: 601 YVAVAAT 607
           YVAVA +
Sbjct: 566 YVAVAVS 572


>gi|223278410 hypothetical protein LOC374977 [Homo sapiens]
          Length = 1323

 Score =  378 bits (970), Expect = e-104
 Identities = 255/812 (31%), Positives = 424/812 (52%), Gaps = 33/812 (4%)

Query: 229  VQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQ 288
            +QEE   SLSSS+R++    +  LS+      LG  +R+EL ++ + S+ +LPSV+ + +
Sbjct: 466  IQEEPLDSLSSSVRKQAMEILTQLSHTQP--TLGMRERSELVNVCVHSVFSLPSVQAMQE 523

Query: 289  IQEIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVKDHERE 348
              E         + LY QT +A   +L++L ++DP    L +I++ L PW+ S K HER 
Sbjct: 524  KDEAKAE---TIQALYHQTLEALQTLLKALFIEDPTPAGLKSILEALGPWMNSGKAHERA 580

Query: 349  RATASMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHI 408
            RA  +   VL  +   L   +PL F  LG L+  + L  GDP E++  EA +GI  +L+ 
Sbjct: 581  RAVNTNVSVLNHMLLTLPFFMPLGFPALGLLLGRLILHIGDPDEEIGCEALDGI-IILYT 639

Query: 409  TLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNELCQ 468
             L L+    DK ++ N K      + FL  ++  + C      R+ + F  FL   ++  
Sbjct: 640  ILELQKRARDK-EETNKKELYESNKHFLGPYNPVSPC--QNILRVIEEFGDFLGPQQIKD 696

Query: 469  FIMTTFDTLKTLKHPC------IQRSAGELLLT--LAKNTESQFEKVPEIMGVICAQLSI 520
             ++   + LK            + + A E++L+  L        E +PEIM  I  QLS 
Sbjct: 697  LLLAALEGLKGSSEAPGKDSREMMQLASEVMLSSVLEWYRHRALEVIPEIMQGIYMQLSH 756

Query: 521  ISQPRVRQQIINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTW-- 578
            I +PR RQ  +  VSL  S    T++V++ L+C P+P N + AE+WR L +  PS     
Sbjct: 757  IQEPRARQVALLPVSLLASS-FMTEVVVALLMC-PLPLNSNGAEMWRQLILCKPSCDVRD 814

Query: 579  ILWRLLRKLQKCHNEPAQE--KMAYVAVAATDALYEVFLGNRLRAATFRLFPQLLMTLLI 636
            +L  LL  L++   +P  +  + + V +AA   L E+   N       R++PQLL+ LLI
Sbjct: 815  LLDLLLGSLKE---KPVTKEGRASIVPLAAASGLCELLSVNSCMGRVRRIYPQLLLALLI 871

Query: 637  QIHHSIGLTMSDVDIPSGLYTEQEVPSEVTPLCFAMQATKTLLLRTCCLQEFNIMEKNKG 696
            Q+H+ IGL +     P     +   PS   P+ + ++  KTLLLR  C  E   +E   G
Sbjct: 872  QVHYHIGLNLPGCVAPPKDTKKGAQPSPFVPVRWVVKVVKTLLLRMGCSYETTFLEDQGG 931

Query: 697  WALLGGKDGHLQGLFLLANALLERNQLLAQKVMYLLVPLLNRGNDKHKLTSAGFFVELLR 756
            W L+   + H +G+ LLA A+++ +     +++YLL+PLL RG++KH++T+  FFVELL+
Sbjct: 932  WELMEQVESHHRGVALLARAMVQYSCQELCRILYLLIPLLERGDEKHRITATAFFVELLQ 991

Query: 757  SPVAKRLPSIYSVARFKDWLQDGNHLFRILGLRGLYNLVGHQEMREDIKSLLPYIVDSLR 816
                +R+P  YS+ R  + L   + + ++L +RGL  L    E    +K+LLP +V  L+
Sbjct: 992  MEQVRRIPEEYSLGRMAEGLSHHDPIMKVLSIRGLVILARRSEKTAKVKALLPSMVKGLK 1051

Query: 817  ETDEKIVLSAIQILLQLV-----RTMDFTTLAAMMRTLFSLFGDVRSDVHRFSVTLFGAA 871
              D  +V+ A+  L  +      + MD      M++ L   F D R  V    + L+G  
Sbjct: 1052 NMDGMLVVEAVHNLKAVFKGRDQKLMDSAVYVEMLQILLPHFSDAREVVRSSCINLYGKV 1111

Query: 872  IKSVKNPDKKSIENQVLDSLVPLLLYSQDENDAVAEESRQVLTICAQFLKWKLPQEVYSK 931
            ++ ++ P  +++E Q++ +LVPLLL  Q+ N  V+++  + L  C+ F+ W+LP+  YS+
Sbjct: 1112 VQKLRAPRTQAMEEQLVSTLVPLLLTMQEGNSKVSQKCVKTLLRCSYFMAWELPKRAYSR 1171

Query: 932  DPWHIKPTEAGTICRFFEKKCKGKINI-LEQTLMYSKNPKLPIRRSAVLFVGLLSKYMDH 990
             PW  +      IC+      +    I L Q+L Y+KN +  +R+ +V+F+G L   M+ 
Sbjct: 1172 KPWDNQQQTVAKICKCLVNTHRDSAFIFLSQSLEYAKNSRASLRKCSVMFIGSLVPCME- 1230

Query: 991  NELRRMGTDWIEDDLRDLLCDPEPSLCIIASQ 1022
            + +     + ++  L +L  DPE S+CI A+Q
Sbjct: 1231 SIMTEDRLNEVKAALDNLRHDPEASVCIYAAQ 1262


>gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5
            [Homo sapiens]
          Length = 1218

 Score =  223 bits (569), Expect = 6e-58
 Identities = 228/890 (25%), Positives = 392/890 (44%), Gaps = 72/890 (8%)

Query: 183  ELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVLVQEERPHSLSSSMR 242
            E K    KL  +  +  +S+A+     A SF  +  A++V  +   ++ E P SL + +R
Sbjct: 359  ETKDPALKLCLVQSVCMVSRAICSSTQAGSFHFTRKAELVAQMMEFIRAEPPDSLRTPIR 418

Query: 243  QEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNTEC 302
            ++  +T   L    V   L  + RA++    + SI+ L     L + +E   +G C  + 
Sbjct: 419  KKAMLTCTYLV--SVEPALDEQARADVIHGCLHSIMAL-----LPEPKE--EDGGCQ-KS 468

Query: 303  LYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVKDHERERATASMAQVLKCLS 362
            LY +T  A  ++L SL+ ++   + L  +I+HL PW++S + HER RA    A +L+   
Sbjct: 469  LYLETLHALEDLLTSLLQRNMTPQGLQIMIEHLSPWIKSPRGHERARALGLSALLLRYFL 528

Query: 363  KHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKKDQ 422
            +HL +   + F  LG L+ L +  C D      +EA + ++SLL++ L  +  + D +D 
Sbjct: 529  EHLRVSALVPFHNLGLLIGLFSPRCADLWPATRQEAVDCVYSLLYLQLGYEGFSRDYRD- 587

Query: 423  QNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKTLKH 482
             ++   L   ++ L +H   A  F+ C   + Q+    L  ++L   ++T F+ L   + 
Sbjct: 588  -DVAERLLSLKDGL-VHPDPAILFHTC-HSVGQIIAKRLPPDQLISLLLTMFEALGDPEK 644

Query: 483  PCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFISRPK 542
             C + +   +   L +      EKVPEI+ V+ ++L       V     ++V L  +  +
Sbjct: 645  NCSRAATVMINCLLQERGGVLQEKVPEIVSVLRSKLQEAQGEHVLPAAQHSVYLLAT--Q 702

Query: 543  YTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMAY- 601
            +   V+S LL  P+P + H   +WR L+VE      +L  LL K+ +  + P +E  A+ 
Sbjct: 703  HCAAVVSSLLGSPLPLDSHTCMLWRALAVEPRLAAQVLGLLLEKMSR--DVPFKESRAFL 760

Query: 602  -----------VAVAATDALYEVFLGNRLRAATFRLFPQLLMTLLIQIHHSIGLTMSDVD 650
                       + ++AT AL+EV        A   L+PQL + LL+++  ++G     V 
Sbjct: 761  LGRTPDRVATLLPLSATCALFEVMSTPAAGPAVLELYPQLFVVLLLRVSCTVG-----VQ 815

Query: 651  IPSGLYTEQE-------VPSEVTPLCFAMQATKTLLLRTCCLQEFNIMEKNKGWALLGGK 703
            +P  L  ++            + P   A+   +++LLR+        M+   GW LL   
Sbjct: 816  LPRNLQAQERRGASPALATRNLEPCSSAVDTLRSMLLRSGSEDVVQRMDLEGGWELLRTS 875

Query: 704  DGHLQGLFLLANALLERNQLLAQKVMYLLVPLLNRGNDKHKLTSAGFFVELLRSPVAKRL 763
             GH +G   LA A+ E        V+  L    +   +  ++T+  F  ELL S VA  L
Sbjct: 876  AGHEEGATRLARAMAEHAGPRLPLVLKTLACTHSSAYENQRVTTTAFLAELLNSNVANDL 935

Query: 764  PSIYSV-----ARFKDWLQDGNHLFRILGLRGLYNLVG--HQEMREDIKSLLPYIVDSLR 816
              + S+     AR KD         R L LRGL NL      ++R     LL  ++  L 
Sbjct: 936  MLLDSLLESLAARQKDTCAS----VRRLVLRGLANLASGCPDKVRTHGPQLLTAMIGGLD 991

Query: 817  ETDEKIVLSAIQILLQLVRTMDF-------TTLAAMMRTLFSLFGDVRSDVHRFSVTLFG 869
            + D      A++ +L L R +         + L  +   +   F   + +    S+ LFG
Sbjct: 992  DGDNPHSPVALEAMLGLARLVHLVESWDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFG 1051

Query: 870  AAIKSVKNPDKKSIENQVLDSLVPLLLYSQDENDAVAEESRQVLTICAQFLKWKLPQEVY 929
               K      +    +QV+  L PLLL+ QD    VA   R  L +C   L  +     +
Sbjct: 1052 HLNKVCHGDCEDVFLDQVVGGLAPLLLHLQDPQATVASACRFALRMCGPNLACEELSAAF 1111

Query: 930  SKDPWHIKPTEAGTICRFFEKKCKGKIN--------ILEQTLMYSKNPKLPIRRSAVLFV 981
             K   H++   A     F    CK  ++        +L   L Y K+    +R +A LF 
Sbjct: 1112 QK---HLQEGRALHFGEFLNTTCKHLMHHFPDLLGRLLTTCLFYFKSSWENVRAAAPLFT 1168

Query: 982  GLLSKYMDHNELRRMGTDWIEDDLRDLLCDPEPSLCIIASQTL-LLVQMA 1030
            G L  + +  +  ++  D +   L+ LL DP P +   A++ L  LV++A
Sbjct: 1169 GFLVLHSEPRQQPQVDLDQLIAALQILLKDPAPEVRTRAAEALGRLVKLA 1218


>gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens]
          Length = 1641

 Score =  223 bits (569), Expect = 6e-58
 Identities = 228/890 (25%), Positives = 392/890 (44%), Gaps = 72/890 (8%)

Query: 183  ELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVLVQEERPHSLSSSMR 242
            E K    KL  +  +  +S+A+     A SF  +  A++V  +   ++ E P SL + +R
Sbjct: 782  ETKDPALKLCLVQSVCMVSRAICSSTQAGSFHFTRKAELVAQMMEFIRAEPPDSLRTPIR 841

Query: 243  QEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNTEC 302
            ++  +T   L    V   L  + RA++    + SI+ L     L + +E   +G C  + 
Sbjct: 842  KKAMLTCTYLV--SVEPALDEQARADVIHGCLHSIMAL-----LPEPKE--EDGGCQ-KS 891

Query: 303  LYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVKDHERERATASMAQVLKCLS 362
            LY +T  A  ++L SL+ ++   + L  +I+HL PW++S + HER RA    A +L+   
Sbjct: 892  LYLETLHALEDLLTSLLQRNMTPQGLQIMIEHLSPWIKSPRGHERARALGLSALLLRYFL 951

Query: 363  KHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKKDQ 422
            +HL +   + F  LG L+ L +  C D      +EA + ++SLL++ L  +  + D +D 
Sbjct: 952  EHLRVSALVPFHNLGLLIGLFSPRCADLWPATRQEAVDCVYSLLYLQLGYEGFSRDYRD- 1010

Query: 423  QNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKTLKH 482
             ++   L   ++ L +H   A  F+ C   + Q+    L  ++L   ++T F+ L   + 
Sbjct: 1011 -DVAERLLSLKDGL-VHPDPAILFHTC-HSVGQIIAKRLPPDQLISLLLTMFEALGDPEK 1067

Query: 483  PCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFISRPK 542
             C + +   +   L +      EKVPEI+ V+ ++L       V     ++V L  +  +
Sbjct: 1068 NCSRAATVMINCLLQERGGVLQEKVPEIVSVLRSKLQEAQGEHVLPAAQHSVYLLAT--Q 1125

Query: 543  YTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMAY- 601
            +   V+S LL  P+P + H   +WR L+VE      +L  LL K+ +  + P +E  A+ 
Sbjct: 1126 HCAAVVSSLLGSPLPLDSHTCMLWRALAVEPRLAAQVLGLLLEKMSR--DVPFKESRAFL 1183

Query: 602  -----------VAVAATDALYEVFLGNRLRAATFRLFPQLLMTLLIQIHHSIGLTMSDVD 650
                       + ++AT AL+EV        A   L+PQL + LL+++  ++G     V 
Sbjct: 1184 LGRTPDRVATLLPLSATCALFEVMSTPAAGPAVLELYPQLFVVLLLRVSCTVG-----VQ 1238

Query: 651  IPSGLYTEQE-------VPSEVTPLCFAMQATKTLLLRTCCLQEFNIMEKNKGWALLGGK 703
            +P  L  ++            + P   A+   +++LLR+        M+   GW LL   
Sbjct: 1239 LPRNLQAQERRGASPALATRNLEPCSSAVDTLRSMLLRSGSEDVVQRMDLEGGWELLRTS 1298

Query: 704  DGHLQGLFLLANALLERNQLLAQKVMYLLVPLLNRGNDKHKLTSAGFFVELLRSPVAKRL 763
             GH +G   LA A+ E        V+  L    +   +  ++T+  F  ELL S VA  L
Sbjct: 1299 AGHEEGATRLARAMAEHAGPRLPLVLKTLACTHSSAYENQRVTTTAFLAELLNSNVANDL 1358

Query: 764  PSIYSV-----ARFKDWLQDGNHLFRILGLRGLYNLVG--HQEMREDIKSLLPYIVDSLR 816
              + S+     AR KD         R L LRGL NL      ++R     LL  ++  L 
Sbjct: 1359 MLLDSLLESLAARQKDTCAS----VRRLVLRGLANLASGCPDKVRTHGPQLLTAMIGGLD 1414

Query: 817  ETDEKIVLSAIQILLQLVRTMDF-------TTLAAMMRTLFSLFGDVRSDVHRFSVTLFG 869
            + D      A++ +L L R +         + L  +   +   F   + +    S+ LFG
Sbjct: 1415 DGDNPHSPVALEAMLGLARLVHLVESWDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFG 1474

Query: 870  AAIKSVKNPDKKSIENQVLDSLVPLLLYSQDENDAVAEESRQVLTICAQFLKWKLPQEVY 929
               K      +    +QV+  L PLLL+ QD    VA   R  L +C   L  +     +
Sbjct: 1475 HLNKVCHGDCEDVFLDQVVGGLAPLLLHLQDPQATVASACRFALRMCGPNLACEELSAAF 1534

Query: 930  SKDPWHIKPTEAGTICRFFEKKCKGKIN--------ILEQTLMYSKNPKLPIRRSAVLFV 981
             K   H++   A     F    CK  ++        +L   L Y K+    +R +A LF 
Sbjct: 1535 QK---HLQEGRALHFGEFLNTTCKHLMHHFPDLLGRLLTTCLFYFKSSWENVRAAAPLFT 1591

Query: 982  GLLSKYMDHNELRRMGTDWIEDDLRDLLCDPEPSLCIIASQTL-LLVQMA 1030
            G L  + +  +  ++  D +   L+ LL DP P +   A++ L  LV++A
Sbjct: 1592 GFLVLHSEPRQQPQVDLDQLIAALQILLKDPAPEVRTRAAEALGRLVKLA 1641


>gi|148727311 hypothetical protein LOC389690 [Homo sapiens]
          Length = 1318

 Score =  223 bits (568), Expect = 7e-58
 Identities = 220/939 (23%), Positives = 404/939 (43%), Gaps = 91/939 (9%)

Query: 169  VEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVL 228
            V+ ++  +   F+     E  K  FL     L  A+   E A S+     ++++  L VL
Sbjct: 398  VDNIVSRMVFYFHYSSWDETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVL 457

Query: 229  VQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQ 288
            +++E   +L +  RQ+     + L    +   +  E +++L S   +S+  LP +  L +
Sbjct: 458  MEKEPQDTLCTRSRQQAMHIASSLC--KLRPPIDLERKSQLLSTCFRSVFALPLLDALEK 515

Query: 289  IQEIM---PNGTC-------------------------NTECLYRQTFQAFSEMLQSLVV 320
               +    PN                            + + LY +T +A   MLQSL++
Sbjct: 516  HTCLFLEPPNIQLWPVARERAGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIM 575

Query: 321  KDPHLENLDTIIKHLVPWLQSVKDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLV 380
            ++P  + L  ++ HL  WL S K HER+RA  S   +LK L+ +  L     F+R+G LV
Sbjct: 576  QNPTADELHFLLSHLYIWLASEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLV 635

Query: 381  ALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHS 440
             ++ +LC DP       + EG   L  + +         K  + L+      +E  + HS
Sbjct: 636  GILGMLCQDPDRATQRCSLEGASHLYQLLM-------CHKTGEALQAESQAPKELSQAHS 688

Query: 441  SAA---------------------KCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKT 479
              A                       F  C F++ +     L   EL   I T  D L +
Sbjct: 689  DGAPLWNSRDQKATPLGPQEMAKNHIFQLCSFQVIKDIMQQLTLAELSDLIWTAIDGLGS 748

Query: 480  LKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFIS 539
               P   ++A E+LLT  +   ++ E V  +   I  +L  +  P+ +++ ++ ++L ++
Sbjct: 749  TS-PFRVQAASEMLLTAVQEHGAKLEIVSSMAQAIRLRLCSVHIPQAKEKTLHAITL-LA 806

Query: 540  RPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQK-------CHN 592
            R    ++V +FL    +P + H  ++WR L    P++  +L  LL  LQ+         +
Sbjct: 807  RSHTCELVATFLNI-SIPLDSHTFQLWRALGAGQPTSHLVLTTLLACLQERPLPTGASDS 865

Query: 593  EPAQEKMAYV-AVAATDALYEVFLGNRLRAATFRLFPQLLMTLLIQIHHSIGLTMSDVDI 651
             P  ++  Y+  +AA + L+E+      + A    +P+L + LL Q+H+ + L +     
Sbjct: 866  SPCPKEKTYLRLLAAMNMLHELQFAREFKQAVQEGYPKLFLALLTQMHYVLELNLPSEPQ 925

Query: 652  PSGLYTEQEVPSEVTPLCFAMQATKTLLLRTCCLQEFNIMEKNKGWALLGGKDGHLQGLF 711
            P     E  VPS  +    +++A K+LL  T    +F  +E    W L      + +G+ 
Sbjct: 926  PKQQAQEAAVPSPQS-CSTSLEALKSLLSTTGHWHDFAHLELQGSWELFTTIHTYPKGVG 984

Query: 712  LLANALLERNQLLAQKVMYLLVPLLNRGNDKHKLTSAGFFVELLRSPV-AKRLPSIYSVA 770
            LLA A+++ +      V+  L+P L    ++ +  +     + L SPV  + LP   ++ 
Sbjct: 985  LLARAMVQNHCRQIPAVLRQLLPSLQSPQERERKVAILILTKFLYSPVLLEVLPKQAALT 1044

Query: 771  RFKDWLQDGNHLFRILGLRGLYNLVGHQEMREDIKSLLPYIVDSLRETDEKIVLSAIQIL 830
                 L D +   R+L L+GL N++ H +    ++  L  ++D   ++ +++++  +  +
Sbjct: 1045 VLAQGLHDPSPEVRVLSLQGLSNILFHPDKGSLLQGQLRPLLDGFFQSSDQVIVCIMGTV 1104

Query: 831  LQLVRTM-----DFTTLAAMMRTLFSLFGDVRSDVHRFSVTLFGAAIKSVKNPDKKSIEN 885
               +  +        +L   + T  S F D R  +   ++ LFG  + ++ + +   +  
Sbjct: 1105 SDTLHRLGAQGTGSQSLGVAISTR-SFFNDERDGIRAAAMALFGDLVAAMADRELSGLRT 1163

Query: 886  QVLDSLVPLLLYSQDENDAVAEESRQVLTICAQFLKWKLPQEVYSKDPWHIKPTEAGTIC 945
            QV  S+VPLLL+ +D+  AVA +++     CA  L+W+L   ++    W     E G   
Sbjct: 1164 QVHQSMVPLLLHLKDQCPAVATQAKFTFYRCAVLLRWRLLHTLFCTLAW-----ERGLSA 1218

Query: 946  RFFEKKC-----KGKINI-LEQTLMYSKNPKLPIRRSAVLFVGLLSKYMDH---NELRRM 996
            R F   C     + + +I L Q L Y  +    I+    LF+G    Y        L  +
Sbjct: 1219 RHFLWTCLMTRSQEEFSIHLSQALSYLHSHSCHIKTWVTLFIGHTICYHPQAVFQMLNAV 1278

Query: 997  GTDWIEDDLRDLLCDPEPSLCIIASQTLLLVQMARAEPK 1035
             T+ +      L  DPEPS+   A+  L  +Q   A PK
Sbjct: 1279 DTNLLFRTFEHLRSDPEPSIREFATSQLSFLQKVSARPK 1317


>gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1706

 Score =  158 bits (399), Expect = 3e-38
 Identities = 191/894 (21%), Positives = 374/894 (41%), Gaps = 64/894 (7%)

Query: 163  PLSEAIVEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIV 222
            P++  I+   + S Q +          K+ F+  +  +++A+   +  + F  +    + 
Sbjct: 832  PITAKIIHHYVSSCQDI--------CLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLT 883

Query: 223  HTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPS 282
              +  +++ E   +L S +R      ++ LS   +     +E+ +EL  ++I S+I+L  
Sbjct: 884  SIIVAVIKAEPTDNLVSPVRALAMEALSHLS--KLKPFYSTEENSELMDISIHSVISL-- 939

Query: 283  VRTLTQIQEIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSV 342
                    ++      + + LY     +  ++++SL+ +    + L  +++ L  W+ S 
Sbjct: 940  --------QLPGEDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSE 991

Query: 343  KDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGI 402
            K+ ERE+A +    +++       + + L+  + G +V L+A    D  ++    +   +
Sbjct: 992  KEWEREKAVSLHLYLMRIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVL 1051

Query: 403  HSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLD 462
             SLL +             Q+ L+    KC+   +L S+  +  +    RIA+V      
Sbjct: 1052 SSLLDLHASQTCSLWGPSKQKELE----KCKG--DLQSTDVEKIFCASSRIAKVVCMEFS 1105

Query: 463  SNELCQFIMTTFDTLKTLKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIIS 522
             +E+   I    +    +     + S   +   L    +   +KV EI+  I   L ++ 
Sbjct: 1106 CDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQMRAKELEDKVAEILSAILVHLPVVD 1165

Query: 523  QPRVRQQIINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWR 582
             P VR+ +I+ + L      + + +L+ LL  P+P   HLAEVW  +S  +P    +L  
Sbjct: 1166 HPEVRRLLIDGILLLAHH--HQETILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHS 1223

Query: 583  LLRKLQK--CHNEPAQEKMAYVAVAATDALYEVFLGNRLRAATFR------LFPQLLMTL 634
            L+ +LQ        A  K     +AA D L  +   + L              P L+ TL
Sbjct: 1224 LMGRLQSRLSPRISATSKADIWRLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTL 1283

Query: 635  LIQIHHSIGLTMSDVDIPS-GLYTEQEVPSEVTPLCFAMQATKTLLLRTCCLQEFNIMEK 693
            L+Q+  S     +   +    L     +P E+      +++ + L  R       + +++
Sbjct: 1284 LLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRVTIKSMQLLFKRVKSQHLAHTLDE 1343

Query: 694  NKGWALLGGKDGHLQGLFLLANALLERNQLLAQKVMYLLVPLLNRGNDKH----KLTSAG 749
               W LL      L+G+ LLA   ++  +   Q+    L  L+ RG D      +++S  
Sbjct: 1344 QAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQR----LAELVLRGMDSEVLSCRISSTA 1399

Query: 750  FFVELLRSPV--AKRLPSIYSVARFKDWLQDGNHLFRILGLRGLYNLV--GHQEMREDIK 805
              VE +  PV   ++L    ++   K   Q+ +   R+L LR L N+     +++++  K
Sbjct: 1400 VCVEFMSGPVLYQEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRK 1459

Query: 806  SLLPYIVDSLRETDEKIV----LSAIQILLQLVRTMDFTTLAAMMRTLFSLFGDVRSDVH 861
             LL   +  LRE     V    + A+  +L  +R  D  +    M     +F D  S++ 
Sbjct: 1460 VLLEKCLGPLREPVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELL 1519

Query: 862  RF-SVTLFGAAIKSVKNPDKKSIENQVLDSLVPLLLYSQDENDAVAEESRQVLTICAQFL 920
            R  +  LFG   + V    K   + +V  + +PL+L+SQD     A+     +  C  F 
Sbjct: 1520 RLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQCVHFW 1579

Query: 921  KWKL------PQEVYSKDPWHIKPTEAGTICRFFEKKCKGKI-NILEQTLMYSKNPKLPI 973
             WK       P +  + D   +  T   T+C    +K    +   L +T+ Y KN    I
Sbjct: 1580 GWKSLEHPSGPSDTATDDKMTVFQT---TMCSILTRKKPAVLYRFLLETMAYVKNNLSRI 1636

Query: 974  RRSAVLFVGLLSKYMDHNELRRMGTDWIEDDLRDLLCDPEPSLCIIASQTLLLV 1027
            R +A    G++ K M  + L+++    + + L++L  DP+P +   A +TL ++
Sbjct: 1637 RIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRAALETLTVL 1690


>gi|154937380 hypothetical protein LOC642475 [Homo sapiens]
          Length = 719

 Score =  157 bits (396), Expect = 6e-38
 Identities = 150/558 (26%), Positives = 253/558 (45%), Gaps = 25/558 (4%)

Query: 493  LLTLAKNTESQFEKVPE----IMGVICAQLSIISQPRVRQQIINTVSLFISRPKYTDIVL 548
            +LTL+   E++ E++ +    ++  + AQ+  +++ R  +  +  +S  ++     D+V 
Sbjct: 132  VLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSA-LALEHARDVVC 190

Query: 549  SFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMAYVAVAATD 608
            + LL   +P +R  AE+WR LS        +L +LL  L+       Q      A+AAT 
Sbjct: 191  A-LLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASGPEPQ------ALAATR 243

Query: 609  ALYEVFLGNRLRAATFRLFPQLLMTLLIQIHHSIGLTMSDVDIPSGLYTEQEVPSEVTPL 668
            AL E+   +    AT   +P LL+ L+ Q+H  +  +    D+P         P      
Sbjct: 244  ALGEMLAVSGCVGATRGFYPHLLLALVTQLH-KLARSPCSPDMPKIWVLSHRGPPHSHAS 302

Query: 669  CFAMQATKTLLLRTCCLQEFNIMEKNKGWALLGGKDGHLQGLFLLANALLERNQLLAQKV 728
            C A++A K LL           ME+  GW  L G   HL+G+ LLA+A++       + +
Sbjct: 303  C-AVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLLLASAMVAHADHHLRGL 361

Query: 729  MYLLVPLLNRGNDKHKLTSAGFFVELLRS-PVAKRLPSIYSVARFKDWLQDGNHLFRILG 787
               L+P L   +D  +LT+  FF  LL+S P A+ L     + R   W  D     R LG
Sbjct: 362  FADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEVILERLLTWQGDPEPTVRWLG 421

Query: 788  LRGLYNLVGHQEMREDIKSLLPYIVDSLRETDEKIV---LSAIQILLQLVRTMDFTTLAA 844
            L GL +L  ++     + +LLP ++ +L E D ++V   L A++ LL   R       A 
Sbjct: 422  LLGLGHLALNRRKVRHVSTLLPALLGALGEGDARLVGAALGALRRLLLRPRAPVRLLSAE 481

Query: 845  MMRTLFSLFGDVRSDVHRFSVTLFGAAIKSVKNPDKKSIENQ----VLDSLVPLLLYSQD 900
            +   L  L  D R  +   +V L G  ++  +   +  +       VL SLVPLLL   D
Sbjct: 482  LGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLGLRGPLRKLVLQSLVPLLLRLHD 541

Query: 901  ENDAVAEESRQVLTICAQFLKWKLPQEVYSKDPWHIKPTEAGTICRFFEKKCKGKINILE 960
             +   AE S   L  C     W L +E+ +   +      +   CR  ++      N L 
Sbjct: 542  PSRDAAESSEWTLARCDHAFCWGLLEELVTVAHYDSPEALSHLCCRLVQRYPGHVPNFLS 601

Query: 961  QTLMYSKNPKLPIRRSAVLFVGLLSKYMDHNELRRMGTDWIEDDLRDLLCDPEPSLCI-- 1018
            QT  Y ++P+ P+RR+A + +G L  +     + +   D +  DL  L  DP+P++    
Sbjct: 602  QTQGYLRSPQDPLRRAAAVLIGFLVHHASPGCVNQDLLDSLFQDLGRLQSDPKPAVAAAA 661

Query: 1019 -IASQTLLLVQMARAEPK 1035
             +++Q + ++  AR  P+
Sbjct: 662  HVSAQQVAMLARARGCPR 679


>gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1723

 Score =  154 bits (389), Expect = 4e-37
 Identities = 194/913 (21%), Positives = 377/913 (41%), Gaps = 88/913 (9%)

Query: 163  PLSEAIVEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIV 222
            P++  I+   + S Q +          K+ F+  +  +++A+   +  + F  +    + 
Sbjct: 835  PITAKIIHHYVSSCQDI--------CLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLT 886

Query: 223  HTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPS 282
              +  +++ E   +L S +R      ++ LS   +     +E+ +EL  ++I S+I+L  
Sbjct: 887  SIIVAVIKAEPTDNLVSPVRALAMEALSHLS--KLKPFYSTEENSELMDISIHSVISL-- 942

Query: 283  VRTLTQIQEIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSV 342
                    ++      + + LY     +  ++++SL+ +    + L  +++ L  W+ S 
Sbjct: 943  --------QLPGEDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSE 994

Query: 343  KDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGI 402
            K+ ERE+A +    +++       + + L+  + G +V L+A    D  ++    +   +
Sbjct: 995  KEWEREKAVSLHLYLMRIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVL 1054

Query: 403  HSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLD 462
             SLL +             Q+ L+    KC+   +L S+  +  +    RIA+V      
Sbjct: 1055 SSLLDLHASQTCSLWGPSKQKELE----KCKG--DLQSTDVEKIFCASSRIAKVVCMEFS 1108

Query: 463  SNELCQFIMTTFDTLKTLKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIIS 522
             +E+   I    +    +     + S   +   L    +   +KV EI+  I   L ++ 
Sbjct: 1109 CDEVVSLIQKLCENTGAMNLQHDKASVTWIASFLQMRAKELEDKVAEILSAILVHLPVVD 1168

Query: 523  QPRVRQQIINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWR 582
             P VR+ +I+ + L      + + +L+ LL  P+P   HLAEVW  +S  +P    +L  
Sbjct: 1169 HPEVRRLLIDGILLLAHH--HQETILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHS 1226

Query: 583  LLRKLQK--CHNEPAQEKMAYVAVAATDALYEVFLGNRLRAATFR------LFPQLLMTL 634
            L+ +LQ        A  K     +AA D L  +   + L              P L+ TL
Sbjct: 1227 LMGRLQSRLSPRISATSKADIWRLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTL 1286

Query: 635  LIQIHHS-----------IGLTMSDVDIPSGLYTEQEVPSEVTPLCFAMQATKTLLLRTC 683
            L+Q+  S           +   +    +P  +  ++     VT     +++ + L  R  
Sbjct: 1287 LLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRCSRGRVT-----IKSMQLLFKRVK 1341

Query: 684  CLQEFNIMEKNKGWALLGGKDGHLQGLFLLANALLERNQLLAQKVMYLLVPLLNRGNDKH 743
                 + +++   W LL      L+G+ LLA   ++  +   Q+    L  L+ RG D  
Sbjct: 1342 SQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQR----LAELVLRGMDSE 1397

Query: 744  ----KLTSAGFFVELLRSPV--AKRLPSIYSVARFKDWLQDGNHLFRILGLRGLYNLV-- 795
                +++S    VE +  PV   ++L    ++   K   Q+ +   R+L LR L N+   
Sbjct: 1398 VLSCRISSTAVCVEFMSGPVLYQEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALG 1457

Query: 796  GHQEMREDIKSLLPYIVDSLRETDEKIV----LSAIQILLQLVRTMDFTTLAAMMRTLFS 851
              +++++  K LL   +  LRE     V    + A+  +L  +R  D  +    M     
Sbjct: 1458 APKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCR 1517

Query: 852  LFGDVRSDVHRF-SVTLFGAAIKSVKNPDKKSIENQVLDSLVPLLLYSQDENDAVAEESR 910
            +F D  S++ R  +  LFG   + V    K   + +V  + +PL+L+SQD     A+   
Sbjct: 1518 IFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACM 1577

Query: 911  QVLTICAQFLKWKL------PQEVYSKDPWHIKPTEAGTICRFFEKKCKGK--------- 955
              +  C  F  WK       P +  + D   I  T   T+C    +K KG+         
Sbjct: 1578 ATMFQCVHFWGWKSLEHPSGPSDTTTDDKMTIFQT---TMCSILVRKPKGEPAHSEKPAV 1634

Query: 956  -INILEQTLMYSKNPKLPIRRSAVLFVGLLSKYMDHNELRRMGTDWIEDDLRDLLCDPEP 1014
                L  T+ Y KN    IR +A    G++ K M  + L+++    + + L++L  DP+P
Sbjct: 1635 LYRFLLXTMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPDP 1694

Query: 1015 SLCIIASQTLLLV 1027
             +   A +TL ++
Sbjct: 1695 GVRRAALETLTVL 1707


>gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1710

 Score =  151 bits (381), Expect = 4e-36
 Identities = 192/898 (21%), Positives = 374/898 (41%), Gaps = 68/898 (7%)

Query: 163  PLSEAIVEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIV 222
            P++  I+   + S Q +          K+ F+  +  +++A+   +  + F  +    + 
Sbjct: 832  PITAKIIHHYVSSCQDI--------CLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLT 883

Query: 223  HTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPS 282
              +  +++ E   +L S +R      ++ LS   +     +E+ +EL  ++I S+I+L  
Sbjct: 884  SIIVAVIKAEPTDNLVSPVRALAMEALSHLS--KLKPFYSTEENSELMDISIHSVISL-- 939

Query: 283  VRTLTQIQEIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSV 342
                    ++      + + LY     +  ++++SL+ +    + L  +++ L  W+ S 
Sbjct: 940  --------QLPGEDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSE 991

Query: 343  KDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGI 402
            K+ ERE+A +    ++        + + L+  + G +V L+A    D  ++    +   +
Sbjct: 992  KEWEREKAVSLHLYLMWIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVL 1051

Query: 403  HSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLD 462
             SLL +             Q+ L+    KC+   +L S+  +  +    RIA+V      
Sbjct: 1052 SSLLDLHASQTCSLWGPSKQKELE----KCKG--DLQSTDVEKIFCASSRIAKVVCMEFS 1105

Query: 463  SNELCQFIMTTFDTLKTLKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIIS 522
             +E+   I    +    +     + S   +   L    +   +KV EI+  I   L ++ 
Sbjct: 1106 CDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQMRAKELEDKVAEILSAILVHLPVVD 1165

Query: 523  QPRVRQQIINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWR 582
             P VR+ +I+ + L     + T  +L+ LL  P+P   HLAEVW  +S  +P    +L  
Sbjct: 1166 HPEVRRLLIDGILLLAHHHQET--ILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHS 1223

Query: 583  LLRKLQKCHNE--PAQEKMAYVAVAATDALYEVFLGNRLRAATFR------LFPQLLMTL 634
            L+ +LQ   +    A  K     +AA D L  +   + L              P L+ TL
Sbjct: 1224 LMGRLQSRLSPRISATSKADIWRLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTL 1283

Query: 635  LIQIHHSIGLTMSDVDIPSG-LYTEQEVPSEVTPLCFAMQATKTLLLRTCCLQEFNIMEK 693
            L+Q+  S     +   +    L     +P E+      +++ + L  R       + +++
Sbjct: 1284 LLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRVTIKSMQLLFKRVKSQHLAHTLDE 1343

Query: 694  NKGWALLGGKDGHLQGLFLLANALLERNQLLAQKVMYLLVPLLNRGNDKH----KLTSAG 749
               W LL      L+G+ LLA   ++  +   Q+    L  L+ RG D      +++S  
Sbjct: 1344 QAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQR----LAELVLRGMDSEVLSCRISSTA 1399

Query: 750  FFVEL----LRSPVA--KRLPSIYSVARFKDWLQDGNHLFRILGLRGLYNLV--GHQEMR 801
              VE+    +  PV   ++L    ++   K   Q+ +   R+L LR L N+     ++++
Sbjct: 1400 VCVEMRHRFMSGPVLYQEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVK 1459

Query: 802  EDIKSLLPYIVDSLRETDEKIV----LSAIQILLQLVRTMDFTTLAAMMRTLFSLFGDVR 857
            +  K LL   +  LRE     V    + A+  +L  +R  D  +    M     +F D  
Sbjct: 1460 QYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNE 1519

Query: 858  SDVHRFSV-TLFGAAIKSVKNPDKKSIENQVLDSLVPLLLYSQDENDAVAEESRQVLTIC 916
            S++ R     LFG   + V    K   + +V  + +PL+L+SQD     A+     +  C
Sbjct: 1520 SELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQC 1579

Query: 917  AQFLKWKL------PQEVYSKDPWHIKPTEAGTICRFFEKKCKGKI-NILEQTLMYSKNP 969
              F  WK       P +  + D   +  T   T+C    +K    +   L +T+ Y KN 
Sbjct: 1580 VHFWGWKSLEHPSGPSDTATDDKMTVFQT---TMCSILTRKKPAVLYRFLLETMAYVKNN 1636

Query: 970  KLPIRRSAVLFVGLLSKYMDHNELRRMGTDWIEDDLRDLLCDPEPSLCIIASQTLLLV 1027
               IR +A    G++ K M  + L+++    + + L++L  DP+P +   A +TL ++
Sbjct: 1637 LSRIRIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRAALETLTVL 1694


>gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]
          Length = 1585

 Score =  142 bits (358), Expect = 2e-33
 Identities = 166/732 (22%), Positives = 317/732 (43%), Gaps = 54/732 (7%)

Query: 207  DETAKSFIHSHIADIVHTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDR 266
            D   + F  S+   ++  +   +++E   SL+S +R +  + I  LS     L L  +D 
Sbjct: 768  DAEDQGFQFSYKEMLIGYMLDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSL--QDH 825

Query: 267  AELFSLTIKSIITLPSVRTLTQIQEIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLE 326
              +    I+ ++ LP +  L    +   +   + + LY ++  A  ++L++++  + + E
Sbjct: 826  LNILEENIRRLLPLPPLENLKSEGQTDKDKE-HIQFLYERSMDALGKLLKTMMWDNVNAE 884

Query: 327  NLDTIIKHLVPWLQSVKDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALL 386
            +   +   L  WL S K+ ERERA    A+VL       +++ P  F ++G L+ L+A  
Sbjct: 885  DCQEMFNLLQMWLVSQKEWERERAFQITAKVLTN-----DIEAPENF-KIGSLLGLLAPH 938

Query: 387  CGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCF 446
              D    + + AA     L +I    K I  + +  Q L+  L      +++  S+    
Sbjct: 939  SCDTLPTIRQAAASSTIGLFYI----KGIHLEVERLQGLQEGLESDDVQVQIKISS---- 990

Query: 447  YNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKTLKHPCIQRSAGELLLTLAKNTESQFE- 505
                 +IA++   F+ + E+  F+    D L++L   C  ++ G  ++T+ K   +  E 
Sbjct: 991  -----KIAKIVSKFIPNEEILMFLEEMLDGLESLNPTCT-KACGIWMITVLKQQGAALED 1044

Query: 506  KVPEIMGVICAQLSIISQPRVRQQ-IINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAE 564
            ++ EI+G I   + ++ Q     Q I+  +S   S   + D V+  LL  P+P++R    
Sbjct: 1045 QLLEILGTIYHHMPVLRQKEESFQFILEAISQIASF--HMDTVVVNLLQKPLPFDRDTKT 1102

Query: 565  VWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMAYVAVAATDALYEVFLGNRLRAATF 624
            +W+ L+ +  S+  +L  L+ KL+    E   +     A++   A+YEV     +  +  
Sbjct: 1103 LWKALAEKPASSGKLLQALIDKLE---TELEDDIARVEAISVACAMYEVI---SMGTSVT 1156

Query: 625  RLFPQLLMTLLIQIHHSIGLTMSDVDIPSGLYTEQEVPSEVTPLCFAMQATKTLLLRTCC 684
             L+P+L   LL  +  ++G  M         +  Q+   +  P    +       L+   
Sbjct: 1157 GLYPELFTLLLKLVSCTLGQKMLTCPWSHRRHVMQQGEQQQIPDPCRLSTATLKCLQAQA 1216

Query: 685  LQEFNIMEKNKG---WALLGGKDGHLQGLFLLANALLERNQLLAQKVMYLLVPLLNRGND 741
            ++E    E ++G   W LL     H  G+  LA ++      +   +M  L+  L   ++
Sbjct: 1217 MREGLAKESDEGDNLWTLLSSPSTHHIGVCSLARSMAVWQHGVILDIMEQLLSSLTSSSE 1276

Query: 742  KHKLTSAGFFVELLRSPVAKRLPSIYSVARFKD---WLQDGNHLFRILGLRGLYNLV--G 796
             +++T A FF EL++ P+  +  ++ +V    D   W  D N   R + +RGL N     
Sbjct: 1277 NYRITGAAFFSELMKEPILWKHGNLRNVLILMDQSAW--DSNATLRQMAIRGLGNTASGA 1334

Query: 797  HQEMREDIKSLLPYIVDSLRETDEKIV----LSAIQILLQLVRTMD----FTTLAAMMRT 848
              ++++  + +L  I+  L       V    L A++ +L+L+   D    F  +    RT
Sbjct: 1335 PHKVKKHKQLMLESIIRGLYHLARTEVVCESLKALKKILELLTDRDVSFYFKEIVLQTRT 1394

Query: 849  LFSLFGDVRSDVHRFSVTLFGAAIKSVKNPDKKSIENQVLDSLVPLLLYSQDENDAVAEE 908
             F    D + DV   ++ LF           K     ++  SL+  LL+  D N  +   
Sbjct: 1395 FFE---DEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLHLWDPNPKIGVA 1451

Query: 909  SRQVLTICAQFL 920
             R VL +C  FL
Sbjct: 1452 CRDVLMVCIPFL 1463


>gi|117956387 hypothetical protein LOC80133 [Homo sapiens]
          Length = 573

 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 112/515 (21%), Positives = 202/515 (39%), Gaps = 54/515 (10%)

Query: 221 IVHTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITL 280
           + H +N L+      + S  +  E  +   + S+ D   LL  E + ++   +   ++ +
Sbjct: 24  MAHKVNSLLD-----AYSGLLSNESMILAVNSSFVDP--LLQFESQLKIIESSFGMLVVM 76

Query: 281 PSVRTLTQIQEIMPNGTC--NTECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPW 338
           PS   L +++E+  +     + E LY      +  +L SLV KD  L  L  I+K ++ W
Sbjct: 77  PS---LDKVKEMGSSYEYIEDMENLYHNILNIYENILTSLVSKD--LYKLQ-ILKEMLVW 130

Query: 339 LQSVKDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEA 398
           +     + +ER    + +VL+     +   + +    LG L A ++LLC      + ++A
Sbjct: 131 MSKDSSYLQERIMVIINKVLRFTVTKVRKYISVDAPCLGLLAAELSLLCSHEDPSIVKQA 190

Query: 399 AEGIHSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFE 458
           + G+  LL+I  R +      K       +L      +E      K F     +IAQ   
Sbjct: 191 SLGMCHLLYIA-RCQNDIGTNKPTNGKSHSLQFPSSDVEF---LPKEFQQDESKIAQRVG 246

Query: 459 GFLDSNELCQFIMTTFDTLKTLKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQL 518
             L    L  F+ +    L +        +A  L+ TL  + E +   V +I+  I  QL
Sbjct: 247 QTLLPPLLTDFVQSLLMKLSSPDDKIASDAASILIFTLEFHAE-KVTMVSKIVDAIYRQL 305

Query: 519 SIISQPRVRQQIINTVSLFI-SRPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTT 577
                  ++  ++  ++L   + PK    V+  L+ +PVP +  L ++W+    +     
Sbjct: 306 C--DNNCMKDVMLQVITLLTCTSPKK---VIFQLMDYPVPADDTLIQMWKAACSQASVAP 360

Query: 578 WILWRLLRKLQKCHNEPAQ----------EKMAYVAVAATDALYEVFLGNRLRAATFRLF 627
            +L  +L  L+    E             +    + +AA  AL         R A  + F
Sbjct: 361 HVLKTILLILKGKPGEMEDTVTEGKRFSLDITNLMPLAACQALCTFLPLGSYRKAVAQYF 420

Query: 628 PQLLMTLLIQIHHSIGLTMSDVDIPSGLYTEQEVPSEVTPLCFAMQATKTLLLRTCCLQE 687
           PQLL TL+ Q+                 Y  +  P       +A  A + +LL    LQ+
Sbjct: 421 PQLLTTLMFQV----------------FYNSELKPILKDRALYAQDALR-VLLNCSGLQQ 463

Query: 688 FNI-MEKNKGWALLGGKDGHLQGLFLLANALLERN 721
            +I + K   W  L     +  G+  +A  L E N
Sbjct: 464 VDITLMKENFWDQLSEDLCYYHGVCFIAKTLSEYN 498


>gi|54112117 splicing factor 3b, subunit 1 isoform 1 [Homo sapiens]
          Length = 1304

 Score = 37.7 bits (86), Expect = 0.057
 Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 5/96 (5%)

Query: 785  ILG-LRGLYNLVGHQEMREDIKSLLPYIVDSLRETDEKIVLSAIQILLQLV-RTMDFTTL 842
            ILG L+ + N++G  +M   IK LLP +   L+   EK+  + I ++ ++  R  ++ + 
Sbjct: 993  ILGALKAIVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEYVSA 1052

Query: 843  AAMMRTLFSLFGDVRSD---VHRFSVTLFGAAIKSV 875
               MR  F L   +++    + R +V  FG   K++
Sbjct: 1053 REWMRICFELLELLKAHKKAIRRATVNTFGYIAKAI 1088


>gi|187761381 maestro isoform d [Homo sapiens]
          Length = 262

 Score = 33.9 bits (76), Expect = 0.83
 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 5/86 (5%)

Query: 839 FTTLAAMMRTLFSLFGDVRSDVHRFSV-TLFGAAIKSVKNPDKKSIENQVLDSLVPLLLY 897
           F  +    RTL     D  +D  R+S   LFG          KK   +QV  +   LL++
Sbjct: 144 FIDITLQTRTLL----DDENDSLRYSAFVLFGQLAAFAGRKWKKFFTSQVKQTRDSLLIH 199

Query: 898 SQDENDAVAEESRQVLTICAQFLKWK 923
            QD N  VA+  +     C+ +LK K
Sbjct: 200 LQDRNPQVAKACKTTFQACSPYLKLK 225


>gi|187761375 maestro isoform a [Homo sapiens]
          Length = 248

 Score = 33.9 bits (76), Expect = 0.83
 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 5/86 (5%)

Query: 839 FTTLAAMMRTLFSLFGDVRSDVHRFSV-TLFGAAIKSVKNPDKKSIENQVLDSLVPLLLY 897
           F  +    RTL     D  +D  R+S   LFG          KK   +QV  +   LL++
Sbjct: 130 FIDITLQTRTLL----DDENDSLRYSAFVLFGQLAAFAGRKWKKFFTSQVKQTRDSLLIH 185

Query: 898 SQDENDAVAEESRQVLTICAQFLKWK 923
            QD N  VA+  +     C+ +LK K
Sbjct: 186 LQDRNPQVAKACKTTFQACSPYLKLK 211


>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 [Homo
            sapiens]
          Length = 1585

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 9/81 (11%)

Query: 953  KGKINILEQTLMYSKNPKLPIRRSAVL---FVGLLSKYMDHNELRRMGTDWIEDDL--RD 1007
            +G I++ E T+ +SK P LP+ R+ VL    + LL K M H   +++G  W E DL  +D
Sbjct: 1330 EGGISMRELTIEFSK-PLLPVGRAGVLLSEILHLLCKQMSH---KKVGALWREADLSWKD 1385

Query: 1008 LLCDPEPSLCIIASQTLLLVQ 1028
             L + E     +  Q L  ++
Sbjct: 1386 FLPEGEDVHNFLLEQKLDFIE 1406


>gi|154277118 spectrin repeat containing, nuclear envelope 1 isoform
           4 [Homo sapiens]
          Length = 3321

 Score = 31.6 bits (70), Expect = 4.1
 Identities = 32/146 (21%), Positives = 62/146 (42%), Gaps = 14/146 (9%)

Query: 303 LYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVK----------DHERERATA 352
           L++QT +     L  L     HLE  + +++ ++ W++  K             + R   
Sbjct: 31  LHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQY 90

Query: 353 SMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALLCGDP-QEKVAEEAAEGIHSLLHITLR 411
            + Q L   SK ++ +L    ++L +L    ++ C +   ++VAE   E       I +R
Sbjct: 91  ILHQTLLEESKEIDSELEAMTEKLQYLT---SVYCTEKMSQQVAELGRETEELRQMIKIR 147

Query: 412 LKYITHDKKDQQNLKRALTKCREFLE 437
           L+ +    KD +  +  L K +  LE
Sbjct: 148 LQNLQDAAKDMKKFEAELKKLQAALE 173


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 31.6 bits (70), Expect = 4.1
 Identities = 32/146 (21%), Positives = 62/146 (42%), Gaps = 14/146 (9%)

Query: 303  LYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVK----------DHERERATA 352
            L++QT +     L  L     HLE  + +++ ++ W++  K             + R   
Sbjct: 5436 LHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQY 5495

Query: 353  SMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALLCGDP-QEKVAEEAAEGIHSLLHITLR 411
             + Q L   SK ++ +L    ++L +L    ++ C +   ++VAE   E       I +R
Sbjct: 5496 ILHQTLLEESKEIDSELEAMTEKLQYLT---SVYCTEKMSQQVAELGRETEELRQMIKIR 5552

Query: 412  LKYITHDKKDQQNLKRALTKCREFLE 437
            L+ +    KD +  +  L K +  LE
Sbjct: 5553 LQNLQDAAKDMKKFEAELKKLQAALE 5578


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 31.6 bits (70), Expect = 4.1
 Identities = 32/146 (21%), Positives = 62/146 (42%), Gaps = 14/146 (9%)

Query: 303  LYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVK----------DHERERATA 352
            L++QT +     L  L     HLE  + +++ ++ W++  K             + R   
Sbjct: 5507 LHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQY 5566

Query: 353  SMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALLCGDP-QEKVAEEAAEGIHSLLHITLR 411
             + Q L   SK ++ +L    ++L +L    ++ C +   ++VAE   E       I +R
Sbjct: 5567 ILHQTLLEESKEIDSELEAMTEKLQYLT---SVYCTEKMSQQVAELGRETEELRQMIKIR 5623

Query: 412  LKYITHDKKDQQNLKRALTKCREFLE 437
            L+ +    KD +  +  L K +  LE
Sbjct: 5624 LQNLQDAAKDMKKFEAELKKLQAALE 5649


>gi|156616294 peptidoglycan recognition protein 2 precursor [Homo
           sapiens]
          Length = 576

 Score = 31.6 bits (70), Expect = 4.1
 Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 12/81 (14%)

Query: 573 LPSTTWILWRLLRKLQKCHNE---PAQEKMAYVAVAATDALYEVFLG-------NRLRAA 622
           L    W    LL++L+  H +    +QE++A VA  AT    E FLG        R  AA
Sbjct: 332 LAQQVWGTLVLLQRLEPVHLQLQCMSQEQLAQVAANATKEFTEAFLGCPAIHPRCRWGAA 391

Query: 623 TFRLFPQLLMTLL--IQIHHS 641
            +R  P+LL   L  + +HH+
Sbjct: 392 PYRGRPKLLQLPLGFLYVHHT 412


>gi|239751877 PREDICTED: hypothetical protein XP_002348035 [Homo
           sapiens]
          Length = 944

 Score = 31.2 bits (69), Expect = 5.4
 Identities = 26/103 (25%), Positives = 39/103 (37%), Gaps = 6/103 (5%)

Query: 3   LSRRGRGSRLAGSRAATSNLPR------ATALSPKSAGRGALSISHAQLLTRRRHSSEQV 56
           L  RGRG    G   A   L +         L  + A  G L+  HA +L +     E +
Sbjct: 731 LGGRGRGGGTRGGGGAVRALVQQQVGGVGEGLGAERAAEGPLARVHALVLPQVGALREAL 790

Query: 57  PPESEPRADFRSGKWLQEPATGDARDSRQALRARMSSKHRICS 99
           P +S              P  G   +   A+RARM ++  +C+
Sbjct: 791 PADSTGVGPLAGVHVAVAPQAGRVLEGLGAVRARMKARRPVCT 833


>gi|28626504 fermitin family homolog 3 short form [Homo sapiens]
          Length = 663

 Score = 30.8 bits (68), Expect = 7.0
 Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 95  HRICSQEEVVIPCAYDSDSESVDLELSNLEIIKKGSSSIELTDLDIPDIPGLHCEPLSHS 154
           +++    EV  P   D   + +D+ LSNLE+  +GS+  ++ D  +  IP L        
Sbjct: 302 NKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSAPTDVLD-SLTTIPELKDHLRIFR 360

Query: 155 PRHLT 159
           PR LT
Sbjct: 361 PRKLT 365


>gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]
          Length = 593

 Score = 30.8 bits (68), Expect = 7.0
 Identities = 36/115 (31%), Positives = 48/115 (41%), Gaps = 6/115 (5%)

Query: 4   SRRGRGSRLAGSRAATSNLPRATALSPKSAGRGALSISHAQLLTRRRHSSEQVPPESEPR 63
           S RGRG   AG+RA     PR + L   SAGRG  S  H     ++    E VP    P 
Sbjct: 377 SIRGRGRGAAGNRAPG---PRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLEIPT 433

Query: 64  ADFRSGK--WLQEPATGDARDSRQALRA-RMSSKHRICSQEEVVIPCAYDSDSES 115
            +  + K   +  PA G       A  A +M    +I + E ++ P A   D  S
Sbjct: 434 VNPVAIKPGTVAIPAIGAQYSMFPAAPAPKMIEDGKIHTVEHMISPIAVQPDPAS 488


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 30.8 bits (68), Expect = 7.0
 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 15/80 (18%)

Query: 12  LAGSRAATSNLP-RATALSPKSAGRGALSISHAQLLTRRRHSSEQVPPESEPRADFRSGK 70
           + G++AAT  LP RA    P    RG               S EQ PP   PRA  R G+
Sbjct: 360 IPGAQAATRGLPGRAARRKPPPLTRG--------------RSVEQSPPRERPRAAGRRGR 405

Query: 71  WLQEPATGDARDSRQALRAR 90
             +      +  +R+A R++
Sbjct: 406 MAEASGRRGSPRARKASRSQ 425


>gi|7662655 SBBI31 protein [Homo sapiens]
          Length = 169

 Score = 30.8 bits (68), Expect = 7.0
 Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 9/136 (6%)

Query: 291 EIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVKDHERERA 350
           E++ NG  +        F A  + L+  + K P + +     KH+  W+  V +  R+  
Sbjct: 25  EVLMNGRKHFVEKRYSEFHALHKKLKKCI-KTPEIPS-----KHVRNWVPKVLEQRRQGL 78

Query: 351 TASMAQVLKCLSKHLNLKLPLRFQRLGHLVAL-MALLCGDPQEKVAEEAAEGIHSLLHIT 409
              +  V+  L      KL L F  + HL +L  A  CG   E  +EE+++  H  + + 
Sbjct: 79  ETYLQAVI--LENEELPKLFLDFLNVRHLPSLPKAESCGSFDETESEESSKLSHQPVLLF 136

Query: 410 LRLKYITHDKKDQQNL 425
           LR  Y+     D  N+
Sbjct: 137 LRDPYVLPAASDFPNV 152


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 30.8 bits (68), Expect = 7.0
 Identities = 37/145 (25%), Positives = 66/145 (45%), Gaps = 20/145 (13%)

Query: 305  RQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSVKDHERERATASMAQVLKCLSKH 364
            R+ ++++ EML S  + DP +             +Q+++D   E     M ++   L++H
Sbjct: 1847 REMYRSYVEMLVSTAL-DPDM-------------IQALEDTHDELYLPPMRKIDGLLNEH 1892

Query: 365  LNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKKDQQN 424
                L    +RL    AL   L   PQ +V E++ EG      + LR     +++K    
Sbjct: 1893 KKKVL----KRLSLSPALQDALHTFPQLQV-EQSGEGSPEEGAVRLRPAGEPYNRKTLSK 1947

Query: 425  LKRALTKCREF-LELHSSAAKCFYN 448
            LKR++ + +EF +EL  S     Y+
Sbjct: 1948 LKRSVVRAQEFKVELEKSGYYTLYH 1972


>gi|76563908 hypothetical protein LOC169436 [Homo sapiens]
          Length = 680

 Score = 30.4 bits (67), Expect = 9.2
 Identities = 17/76 (22%), Positives = 36/76 (47%)

Query: 325 LENLDTIIKHLVPWLQSVKDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLVALMA 384
           +E ++T +KH++  ++ + DH   +A   +  +LK    H+++   L     G + +L  
Sbjct: 45  VEEMETKVKHVIKQVECMDDHYASQALEELMPLLKLRHAHISVYQELFITWNGEISSLYL 104

Query: 385 LLCGDPQEKVAEEAAE 400
            L  +  E   +E  E
Sbjct: 105 CLVMEFNELSFQEVIE 120


>gi|239746217 PREDICTED: zinc finger protein 66 [Homo sapiens]
          Length = 1114

 Score = 30.4 bits (67), Expect = 9.2
 Identities = 58/244 (23%), Positives = 95/244 (38%), Gaps = 41/244 (16%)

Query: 135  LTDLDIPDIPGLHCEPLSH------SPRHLTQQDPLS----EAIVEKLIQSIQKVFNGEL 184
            L+ + +P+   + C+PLSH      SP HL+Q + L         EK + S   V + E 
Sbjct: 851  LSPIHLPEWKPVPCQPLSHHTGKLFSPTHLSQWETLHCEPLNHYCEKPVHSESLVQHSEK 910

Query: 185  KGELEKLKFLGDLSSLSQALPYDETAK-SFIHS------HIADIVHTLNVLVQEERPHSL 237
               +  +     L +++ +    ET   S  HS      H    VH    L     P S 
Sbjct: 911  LFTVSHIFNKRYLITVTHSFTTVETCSLSSNHSPQCEPVHCQPFVHYCGYLFTLTHPFST 970

Query: 238  SSSMRQEVFVTIADLSYQDVHLLLGSEDRA--ELFSLTIKSIITL---------PSVRTL 286
               +R    +      +   H L+    R+  +LF++T +SIITL          +  + 
Sbjct: 971  WEPVRCLSLIHQNGNLFTFTHSLITKLIRSSGKLFTVT-QSIITLRICSLGKHFNATHSF 1029

Query: 287  TQIQEIMPNGTCNTECLYRQTFQAFS----EMLQSLVVKDP--------HLENLDTIIKH 334
            T +     + T ++E +YRQT    S     +  S +  +P        H  NL T+   
Sbjct: 1030 TAVVICSLSATQSSEPVYRQTLILNSGYKLTVTLSFITWEPVHCHPHIHHSGNLFTLTNS 1089

Query: 335  LVPW 338
            L+ W
Sbjct: 1090 LITW 1093


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 30.4 bits (67), Expect = 9.2
 Identities = 44/171 (25%), Positives = 63/171 (36%), Gaps = 36/171 (21%)

Query: 2   PLSRRGRGSRLAGSRAATSNLPRATALSPKSAGRGALS----ISHAQLLTRRRHSSEQVP 57
           P +R  +G+R AG +A    LP A    P+ A  G L        A   T  +  S Q P
Sbjct: 40  PATRTTKGAREAGGQAQAMELPEA---QPRQARDGELKPPSLRGQAPSSTPGKRGSPQTP 96

Query: 58  PESEPRADFRSGKWLQEPATGDARDSRQALRARMSSKHRICSQEEVVIPCAYDSDSESVD 117
           P   P         LQ P       SR A RA  S   R       ++  A      ++D
Sbjct: 97  PGRSP---------LQAP-------SRLAGRAEGSPPQR------YILGIASSRTKPTLD 134

Query: 118 LELSNLEIIKKGSSSIELTDLDIPDIPGLHCEPLSHSPRHLTQQDPLSEAI 168
               N ++      + +L ++D P  PG         PR  T+  P +E +
Sbjct: 135 ETPENPQL-----EAAQLPEVDTPQGPGTGAPLRPGLPR--TEAQPAAEEL 178


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,546,346
Number of Sequences: 37866
Number of extensions: 1617653
Number of successful extensions: 4353
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 4269
Number of HSP's gapped (non-prelim): 55
length of query: 1052
length of database: 18,247,518
effective HSP length: 113
effective length of query: 939
effective length of database: 13,968,660
effective search space: 13116571740
effective search space used: 13116571740
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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