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Search of human proteins with 194473724
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194473724 adaptor-related protein complex 1, mu 1 subunit
isoform 1 [Homo sapiens]
(435 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194473724 adaptor-related protein complex 1, mu 1 subunit iso... 878 0.0
gi|14210504 adaptor-related protein complex 1, mu 1 subunit isof... 840 0.0
gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo... 693 0.0
gi|68799814 adaptor-related protein complex 2, mu 1 subunit isof... 322 3e-88
gi|14917109 adaptor-related protein complex 2, mu 1 subunit isof... 320 2e-87
gi|14917111 adaptor-related protein complex 4, mu 1 subunit [Hom... 180 2e-45
gi|6912240 adaptor-related protein complex 3, mu 1 subunit [Homo... 177 2e-44
gi|46370095 adaptor-related protein complex 3, mu 1 subunit [Hom... 177 2e-44
gi|197209857 adaptor-related protein complex 3, mu 2 subunit [Ho... 166 3e-41
gi|5803000 adaptor-related protein complex 3, mu 2 subunit [Homo... 166 3e-41
gi|26787993 stonin 1 [Homo sapiens] 70 5e-12
gi|29553944 STON1-GTF2A1L protein [Homo sapiens] 70 5e-12
gi|21361863 stonin 2 [Homo sapiens] 69 1e-11
gi|11863154 archain isoform 1 [Homo sapiens] 40 0.005
gi|224451116 Mu-2 related death-inducing protein [Homo sapiens] 39 0.012
gi|88703051 adaptor-related protein complex 1, sigma 3 subunit [... 33 0.66
gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [H... 32 1.5
gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [H... 31 1.9
gi|189409104 adaptor-related protein complex 4, sigma 1 subunit ... 31 1.9
gi|70906430 adaptor-related protein complex 2, sigma 1 subunit i... 31 2.5
gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens] 30 3.3
gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens] 30 3.3
gi|94981553 slow cardiac myosin regulatory light chain 2 [Homo s... 30 3.3
gi|94557295 mitogen-activated protein kinase 8 interacting prote... 30 5.6
gi|11038643 adaptor-related protein complex 2, sigma 1 subunit i... 30 5.6
gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens] 29 7.3
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 29 7.3
gi|45439365 transmembrane protein 180 [Homo sapiens] 29 7.3
gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens] 29 9.6
gi|119874201 furry-like [Homo sapiens] 29 9.6
>gi|194473724 adaptor-related protein complex 1, mu 1 subunit
isoform 1 [Homo sapiens]
Length = 435
Score = 878 bits (2269), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 1 MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI 60
MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI
Sbjct: 1 MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI 60
Query: 61 KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF 120
KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF
Sbjct: 61 KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF 120
Query: 121 GYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVN 180
GYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVN
Sbjct: 121 GYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVN 180
Query: 181 LLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKS 240
LLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKS
Sbjct: 181 LLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKS 240
Query: 241 KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSH 300
KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSH
Sbjct: 241 KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSH 300
Query: 301 SRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSF 360
SRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSF
Sbjct: 301 SRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSF 360
Query: 361 PGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPW 420
PGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPW
Sbjct: 361 PGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPW 420
Query: 421 VRYITQNGDYQLRTQ 435
VRYITQNGDYQLRTQ
Sbjct: 421 VRYITQNGDYQLRTQ 435
>gi|14210504 adaptor-related protein complex 1, mu 1 subunit isoform
2 [Homo sapiens]
Length = 423
Score = 840 bits (2171), Expect = 0.0
Identities = 423/435 (97%), Positives = 423/435 (97%), Gaps = 12/435 (2%)
Query: 1 MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI 60
MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI
Sbjct: 1 MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI 60
Query: 61 KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF 120
KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF
Sbjct: 61 KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF 120
Query: 121 GYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVN 180
GYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVN
Sbjct: 121 GYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVN 180
Query: 181 LLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKS 240
LL VSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKS
Sbjct: 181 LL------------VSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKS 228
Query: 241 KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSH 300
KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSH
Sbjct: 229 KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSH 288
Query: 301 SRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSF 360
SRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSF
Sbjct: 289 SRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSF 348
Query: 361 PGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPW 420
PGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPW
Sbjct: 349 PGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPW 408
Query: 421 VRYITQNGDYQLRTQ 435
VRYITQNGDYQLRTQ
Sbjct: 409 VRYITQNGDYQLRTQ 423
>gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo
sapiens]
Length = 423
Score = 693 bits (1789), Expect = 0.0
Identities = 337/434 (77%), Positives = 389/434 (89%), Gaps = 12/434 (2%)
Query: 1 MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI 60
MSASAV++LD+KGK LI RNY+GDV MS++EHFMP+L+++EEEG L+P+L+HG V F+WI
Sbjct: 1 MSASAVFILDVKGKPLISRNYKGDVAMSKIEHFMPLLVQREEEGALAPLLSHGQVHFLWI 60
Query: 61 KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF 120
KH+NLYLVAT+ KNA SLV+SFLYK ++VF EYFKELEEESIRDNFVI+YELLDELMDF
Sbjct: 61 KHSNLYLVATTSKNANASLVYSFLYKTIEVFCEYFKELEEESIRDNFVIVYELLDELMDF 120
Query: 121 GYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVN 180
G+PQTTDSKILQEYITQ+ +KLETG R P TVTNAVSWRSEGIKY+KNEVF+DVIESVN
Sbjct: 121 GFPQTTDSKILQEYITQQSNKLETGKSRVPPTVTNAVSWRSEGIKYKKNEVFIDVIESVN 180
Query: 181 LLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKS 240
LL V+ANG+VL SEIVG+IK++VFLSGMPELRLGLND+VLF+ TGR K+
Sbjct: 181 LL------------VNANGSVLLSEIVGTIKLKVFLSGMPELRLGLNDRVLFELTGRSKN 228
Query: 241 KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSH 300
KSVELEDVKFHQCVRLSRF+NDRTISFIPPDG+FELMSYRL+T VKPLIWIESVIEK SH
Sbjct: 229 KSVELEDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQVKPLIWIESVIEKFSH 288
Query: 301 SRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSF 360
SR+E M+KAK QFK++S AN VEI +PVP+DADSP+FKT+VGS K+VPE + ++WSIKSF
Sbjct: 289 SRVEIMVKAKGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPERNVVIWSIKSF 348
Query: 361 PGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPW 420
PGGKEYLMRAHFGLPSVE E+ EG+PPI VKFEIPYFT SGIQVRY+KIIEKSGYQALPW
Sbjct: 349 PGGKEYLMRAHFGLPSVEKEEVEGRPPIGVKFEIPYFTVSGIQVRYMKIIEKSGYQALPW 408
Query: 421 VRYITQNGDYQLRT 434
VRYITQ+GDYQLRT
Sbjct: 409 VRYITQSGDYQLRT 422
>gi|68799814 adaptor-related protein complex 2, mu 1 subunit isoform
b [Homo sapiens]
Length = 433
Score = 322 bits (826), Expect = 3e-88
Identities = 171/442 (38%), Positives = 265/442 (59%), Gaps = 28/442 (6%)
Query: 6 VYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNL 65
+++ + KG+VLI R YR D+ + V+ F ++ ++ + SP+ F +K +N+
Sbjct: 5 LFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHVKRSNI 63
Query: 66 YLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQT 125
+L A +K+N ++VF FLYK+ V + YF ++ EE+I++NFV+IYELLDE++DFGYPQ
Sbjct: 64 WLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGYPQN 123
Query: 126 TDSKILQEYITQEGHKLETGAPRPPAT--VTNAVSWRSEGIKYRKNEVFLDVIESVNLLG 183
+++ L+ +ITQ+G K +T + T VT + WR EGIKYR+NE+FLDV+ESVNLL
Sbjct: 124 SETGALKTFITQQGIKSQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLL- 182
Query: 184 KYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKS--- 240
+S G VL + + G + M+ +LSGMPE + G+NDK++ + G+G +
Sbjct: 183 -----------MSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADET 231
Query: 241 -----KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVI 295
+S+ ++D FHQCVRLS+F+++R+ISFIPPDGEFELM YR + + ++
Sbjct: 232 SKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLV 291
Query: 296 EKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVW 355
+ +++E + KS FK A +E+ IP P + + G K+ + IVW
Sbjct: 292 REVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVW 351
Query: 356 SIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEK--- 412
IK G KE + A L + K +PPIS+ FE+P F SG++VRYLK+ E
Sbjct: 352 KIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVP-FAPSGLKVRYLKVFEPKLN 410
Query: 413 -SGYQALPWVRYITQNGDYQLR 433
S + + WVRYI ++G Y+ R
Sbjct: 411 YSDHDVIKWVRYIGRSGIYETR 432
>gi|14917109 adaptor-related protein complex 2, mu 1 subunit isoform
a [Homo sapiens]
Length = 435
Score = 320 bits (819), Expect = 2e-87
Identities = 169/444 (38%), Positives = 265/444 (59%), Gaps = 30/444 (6%)
Query: 6 VYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNL 65
+++ + KG+VLI R YR D+ + V+ F ++ ++ + SP+ F +K +N+
Sbjct: 5 LFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHVKRSNI 63
Query: 66 YLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQT 125
+L A +K+N ++VF FLYK+ V + YF ++ EE+I++NFV+IYELLDE++DFGYPQ
Sbjct: 64 WLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGYPQN 123
Query: 126 TDSKILQEYITQEG----HKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVNL 181
+++ L+ +ITQ+G H+ + + + VT + WR EGIKYR+NE+FLDV+ESVNL
Sbjct: 124 SETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNL 183
Query: 182 LGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKS- 240
L +S G VL + + G + M+ +LSGMPE + G+NDK++ + G+G +
Sbjct: 184 L------------MSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTAD 231
Query: 241 -------KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIES 293
+S+ ++D FHQCVRLS+F+++R+ISFIPPDGEFELM YR + +
Sbjct: 232 ETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIP 291
Query: 294 VIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEI 353
++ + +++E + KS FK A +E+ IP P + + G K+ + I
Sbjct: 292 LVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAI 351
Query: 354 VWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEK- 412
VW IK G KE + A L + K +PPIS+ FE+P F SG++VRYLK+ E
Sbjct: 352 VWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVP-FAPSGLKVRYLKVFEPK 410
Query: 413 ---SGYQALPWVRYITQNGDYQLR 433
S + + WVRYI ++G Y+ R
Sbjct: 411 LNYSDHDVIKWVRYIGRSGIYETR 434
>gi|14917111 adaptor-related protein complex 4, mu 1 subunit [Homo
sapiens]
Length = 453
Score = 180 bits (457), Expect = 2e-45
Identities = 126/467 (26%), Positives = 224/467 (47%), Gaps = 54/467 (11%)
Query: 4 SAVYVLDLKGKVLICRNYRGDV---DMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI 60
S ++L KG LI +++RGD D++E+ + + +E + ++ H G F+ I
Sbjct: 3 SQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPV---VMHHHGRHFIHI 59
Query: 61 KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF 120
+H+ LYLV T+ +N + L ++ + +Y L E +I N ++YELLDE++D+
Sbjct: 60 RHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDY 119
Query: 121 GYPQTTDSKILQEYITQE------------------GHKLETGAPRPPATVTNAV-SWRS 161
GY QTT +++L+ +I E G + + P + + V S RS
Sbjct: 120 GYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRS 179
Query: 162 EGIKYRKNEVFLDVIESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPE 221
+ + +KNEVFLDV+E +++L +++NG++L+ ++ G I+++ FL E
Sbjct: 180 D--QSQKNEVFLDVVERLSVL------------IASNGSLLKVDVQGEIRLKSFLPSGSE 225
Query: 222 LRLGLNDKVLFDNTG-RGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYR 280
+R+GL ++ + RG + +++V FH V L FE+ R + PP GE +M Y+
Sbjct: 226 MRIGLTEEFCVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQ 285
Query: 281 LNTHVK---PLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKF 337
L+ + P SV R++ +K + +S A NV +H+P+P S
Sbjct: 286 LSDDLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQ 345
Query: 338 KTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKP---------PI 388
+ + K + W + GG + +P G P
Sbjct: 346 ELSSPEQKAELAEGALRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPA 405
Query: 389 SVKFEIPYFTTSGIQVRYLKIIEKSGYQALP--WVRYITQNGDYQLR 433
S+ FE+P T SG+QVR+L++ + A P WVR+++ + Y +R
Sbjct: 406 SLSFELPRHTCSGLQVRFLRLAFRPCGNANPHKWVRHLSHSDAYVIR 452
>gi|6912240 adaptor-related protein complex 3, mu 1 subunit [Homo
sapiens]
Length = 418
Score = 177 bits (448), Expect = 2e-44
Identities = 118/445 (26%), Positives = 213/445 (47%), Gaps = 45/445 (10%)
Query: 5 AVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNN 64
++++++ G + + ++++ V S ++F + + + P+++ + I +
Sbjct: 4 SLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIYRDK 63
Query: 65 LYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQ 124
L+ V+ + V FL++V F +YF E E +I+DN VI+YELL+E++D G+P
Sbjct: 64 LFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNGFPL 123
Query: 125 TTDSKILQEYI----------TQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLD 174
T+S IL+E I G P ++N + WR G+KY NE + D
Sbjct: 124 ATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSN-IPWRRAGVKYTNNEAYFD 182
Query: 175 VIESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDN 234
V+E ++ + + +G+ + +EI G I + LSGMP+L L + L
Sbjct: 183 VVEEIDAI------------IDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRL--- 227
Query: 235 TGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTH--VKPLIWIE 292
L+DV FH C+R R+E++R +SFIPPDG F L+SYR+++ V ++++
Sbjct: 228 ----------LDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVK 277
Query: 293 SVI---EKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPE 349
I E S R + I K + T + + + +P + T GS + P
Sbjct: 278 HSISFKENSSCGRFDITIGPKQNMGK--TIEGITVTVHMPKVVLNMNLTPTQGSYTFDPV 335
Query: 350 NSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKI 409
+ W + K ++ L S A E P ++++F+I SG++V L +
Sbjct: 336 TKVLTWDVGKITPQKLPSLKGLVNLQS-GAPKPEENPSLNIQFKIQQLAISGLKVNRLDM 394
Query: 410 IEKSGYQALPWVRYITQNGDYQLRT 434
+ Y+ V+Y+T+ G +Q+RT
Sbjct: 395 YGEK-YKPFKGVKYVTKAGKFQVRT 418
>gi|46370095 adaptor-related protein complex 3, mu 1 subunit [Homo
sapiens]
Length = 418
Score = 177 bits (448), Expect = 2e-44
Identities = 118/445 (26%), Positives = 213/445 (47%), Gaps = 45/445 (10%)
Query: 5 AVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNN 64
++++++ G + + ++++ V S ++F + + + P+++ + I +
Sbjct: 4 SLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIYRDK 63
Query: 65 LYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQ 124
L+ V+ + V FL++V F +YF E E +I+DN VI+YELL+E++D G+P
Sbjct: 64 LFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNGFPL 123
Query: 125 TTDSKILQEYI----------TQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLD 174
T+S IL+E I G P ++N + WR G+KY NE + D
Sbjct: 124 ATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSN-IPWRRAGVKYTNNEAYFD 182
Query: 175 VIESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDN 234
V+E ++ + + +G+ + +EI G I + LSGMP+L L + L
Sbjct: 183 VVEEIDAI------------IDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRL--- 227
Query: 235 TGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTH--VKPLIWIE 292
L+DV FH C+R R+E++R +SFIPPDG F L+SYR+++ V ++++
Sbjct: 228 ----------LDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVK 277
Query: 293 SVI---EKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPE 349
I E S R + I K + T + + + +P + T GS + P
Sbjct: 278 HSISFKENSSCGRFDITIGPKQNMGK--TIEGITVTVHMPKVVLNMNLTPTQGSYTFDPV 335
Query: 350 NSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKI 409
+ W + K ++ L S A E P ++++F+I SG++V L +
Sbjct: 336 TKVLTWDVGKITPQKLPSLKGLVNLQS-GAPKPEENPSLNIQFKIQQLAISGLKVNRLDM 394
Query: 410 IEKSGYQALPWVRYITQNGDYQLRT 434
+ Y+ V+Y+T+ G +Q+RT
Sbjct: 395 YGEK-YKPFKGVKYVTKAGKFQVRT 418
>gi|197209857 adaptor-related protein complex 3, mu 2 subunit [Homo
sapiens]
Length = 418
Score = 166 bits (421), Expect = 3e-41
Identities = 115/449 (25%), Positives = 207/449 (46%), Gaps = 53/449 (11%)
Query: 5 AVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNN 64
++++++ G + + ++++ V S ++F E + P++ + + +
Sbjct: 4 SLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHK 63
Query: 65 LYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQ 124
++ VA + V FL++VV F +YF E I+DN V++YE+L+E++D G+P
Sbjct: 64 IFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPL 123
Query: 125 TTDSKILQEYI----------------TQEGHKLETGAPRPPATVTNAVSWRSEGIKYRK 168
T+S IL+E I T G +L TG + V WR G+KY
Sbjct: 124 ATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQ-------LSVVPWRRTGVKYTN 176
Query: 169 NEVFLDVIESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLND 228
NE + DVIE ++ + + +G+ + +EI G I V L+GMP+L L +
Sbjct: 177 NEAYFDVIEEIDAI------------IDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMN 224
Query: 229 KVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRL---NTHV 285
L L+DV FH CVR R+E++R +SFIPPDG F L+SY + N
Sbjct: 225 PRL-------------LDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVA 271
Query: 286 KPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVK 345
P+ ++ + S S + I + T V + +P + + G+
Sbjct: 272 IPVYVKHNISFRDSSSLGRFEITVGPKQTMGKTIEGVTVTSQMPKGVLNMSLTPSQGTHT 331
Query: 346 WVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVR 405
+ P + W + K ++ L + ++ E P I+++F+I SG++V
Sbjct: 332 FDPVTKMLSWDVGKINPQKLPSLKGTMSLQAGASKPDE-NPTINLQFKIQQLAISGLKVN 390
Query: 406 YLKIIEKSGYQALPWVRYITQNGDYQLRT 434
L + + Y+ ++Y+T+ G +Q+RT
Sbjct: 391 RLDMYGEK-YKPFKGIKYMTKAGKFQVRT 418
>gi|5803000 adaptor-related protein complex 3, mu 2 subunit [Homo
sapiens]
Length = 418
Score = 166 bits (421), Expect = 3e-41
Identities = 115/449 (25%), Positives = 207/449 (46%), Gaps = 53/449 (11%)
Query: 5 AVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNN 64
++++++ G + + ++++ V S ++F E + P++ + + +
Sbjct: 4 SLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHK 63
Query: 65 LYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQ 124
++ VA + V FL++VV F +YF E I+DN V++YE+L+E++D G+P
Sbjct: 64 IFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPL 123
Query: 125 TTDSKILQEYI----------------TQEGHKLETGAPRPPATVTNAVSWRSEGIKYRK 168
T+S IL+E I T G +L TG + V WR G+KY
Sbjct: 124 ATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQ-------LSVVPWRRTGVKYTN 176
Query: 169 NEVFLDVIESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLND 228
NE + DVIE ++ + + +G+ + +EI G I V L+GMP+L L +
Sbjct: 177 NEAYFDVIEEIDAI------------IDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMN 224
Query: 229 KVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRL---NTHV 285
L L+DV FH CVR R+E++R +SFIPPDG F L+SY + N
Sbjct: 225 PRL-------------LDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVA 271
Query: 286 KPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVK 345
P+ ++ + S S + I + T V + +P + + G+
Sbjct: 272 IPVYVKHNISFRDSSSLGRFEITVGPKQTMGKTIEGVTVTSQMPKGVLNMSLTPSQGTHT 331
Query: 346 WVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVR 405
+ P + W + K ++ L + ++ E P I+++F+I SG++V
Sbjct: 332 FDPVTKMLSWDVGKINPQKLPSLKGTMSLQAGASKPDE-NPTINLQFKIQQLAISGLKVN 390
Query: 406 YLKIIEKSGYQALPWVRYITQNGDYQLRT 434
L + + Y+ ++Y+T+ G +Q+RT
Sbjct: 391 RLDMYGEK-YKPFKGIKYMTKAGKFQVRT 418
>gi|26787993 stonin 1 [Homo sapiens]
Length = 735
Score = 69.7 bits (169), Expect = 5e-12
Identities = 70/295 (23%), Positives = 112/295 (37%), Gaps = 63/295 (21%)
Query: 166 YRKNEVFLDVIESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLG 225
Y + E+ L++++ N GK V+ G + S ++ I F++G E L
Sbjct: 410 YEEQEISLEIVD--NFWGK----------VTKEGKFVESAVITQIYCLCFVNGNLECFLT 457
Query: 226 LNDKVLFDNTGR-----GKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDG-EFELMSY 279
LND L + K +++ D FH+CV + FE R I F+P D FELM +
Sbjct: 458 LNDLELPKRDESYYEKDSEKKGIDILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRF 517
Query: 280 R--LNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTA------NNVEIHIPVPND 331
+ N P V+ + ++ ++ + S +R S A +N+ IH PVP+
Sbjct: 518 KTLYNGDNLPFSLKSVVVVQGAYVELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQ 577
Query: 332 --------------------------------ADSPKFKTTVGSVKWVPENSEIVWSIKS 359
P + TVGS K+ +VW I
Sbjct: 578 WIKALWTMNLQRQKSLKAKMNRRACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDR 637
Query: 360 FPGGKEYLMRAH-----FGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKI 409
P L H L S + + P +V+F +P S +VR L +
Sbjct: 638 LPDKNSSLDHPHCLSYKLELGSDQEIPSDWYPFATVQFSVPDTCASRTEVRSLGV 692
>gi|29553944 STON1-GTF2A1L protein [Homo sapiens]
Length = 1182
Score = 69.7 bits (169), Expect = 5e-12
Identities = 70/295 (23%), Positives = 112/295 (37%), Gaps = 63/295 (21%)
Query: 166 YRKNEVFLDVIESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLG 225
Y + E+ L++++ N GK V+ G + S ++ I F++G E L
Sbjct: 410 YEEQEISLEIVD--NFWGK----------VTKEGKFVESAVITQIYCLCFVNGNLECFLT 457
Query: 226 LNDKVLFDNTGR-----GKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDG-EFELMSY 279
LND L + K +++ D FH+CV + FE R I F+P D FELM +
Sbjct: 458 LNDLELPKRDESYYEKDSEKKGIDILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRF 517
Query: 280 R--LNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTA------NNVEIHIPVPND 331
+ N P V+ + ++ ++ + S +R S A +N+ IH PVP+
Sbjct: 518 KTLYNGDNLPFSLKSVVVVQGAYVELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQ 577
Query: 332 --------------------------------ADSPKFKTTVGSVKWVPENSEIVWSIKS 359
P + TVGS K+ +VW I
Sbjct: 578 WIKALWTMNLQRQKSLKAKMNRRACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDR 637
Query: 360 FPGGKEYLMRAH-----FGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKI 409
P L H L S + + P +V+F +P S +VR L +
Sbjct: 638 LPDKNSSLDHPHCLSYKLELGSDQEIPSDWYPFATVQFSVPDTCASRTEVRSLGV 692
>gi|21361863 stonin 2 [Homo sapiens]
Length = 905
Score = 68.6 bits (166), Expect = 1e-11
Identities = 73/315 (23%), Positives = 117/315 (37%), Gaps = 67/315 (21%)
Query: 163 GIKYRKNEVFLDVIESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPEL 222
G+ Y + E+ +DV + + G + +L+ ++ I + FLSG+ E
Sbjct: 563 GLNYLEEEITVDVRDEFS-----------GIVSKGDNQILQHHVLTRIHILSFLSGLAEC 611
Query: 223 RLGLNDKVLFDN--------TGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDG-E 273
RLGLND ++ N +K ++L + +FH CV F N R I F P D
Sbjct: 612 RLGLNDILVKGNEIVLRQDIMPTTTTKWIKLHECRFHGCVDEDVFHNSRVILFNPLDACR 671
Query: 274 FELMSYRLNTHVKPLIWI--------ESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIH 325
FELM +R K L + + +E S R+ A + NV I
Sbjct: 672 FELMRFRTVFAEKTLPFTLRTATSVNGAEVEVQSWLRMSTGFSANRDPLTQVPCENVMIR 731
Query: 326 IPVPND--------------------------------ADSPKFKTTVGSVKWVPENSEI 353
PVP++ P + T+G+ K+ + I
Sbjct: 732 YPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSTSVSGSEPVMRVTLGTAKYEHAFNSI 791
Query: 354 VWSIKSFP-----GGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLK 408
VW I P G + H L S ++V+F +P + S VR +
Sbjct: 792 VWRINRLPDKNSASGHPHCFFCHLELGSDREVPSRFANHVNVEFSMPTTSASKASVRSIS 851
Query: 409 IIEKSGYQALPWVRY 423
+ +K+ + WV Y
Sbjct: 852 VEDKTDVR--KWVNY 864
>gi|11863154 archain isoform 1 [Homo sapiens]
Length = 511
Score = 39.7 bits (91), Expect = 0.005
Identities = 27/137 (19%), Positives = 58/137 (42%), Gaps = 1/137 (0%)
Query: 5 AVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNN 64
A V GK ++ R + ++ + +E + + G + VR+++
Sbjct: 5 AAAVCTKAGKAIVSRQFV-EMTRTRIEGLLAAFPKLMNTGKQHTFVETESVRYVYQPMEK 63
Query: 65 LYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQ 124
LY+V + KN+ + L +V EY + LEE I ++ + DE++ GY +
Sbjct: 64 LYMVLITTKNSNILEDLETLRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALGYRE 123
Query: 125 TTDSKILQEYITQEGHK 141
+ ++ + + H+
Sbjct: 124 NVNLAQIRTFTEMDSHE 140
>gi|224451116 Mu-2 related death-inducing protein [Homo sapiens]
Length = 490
Score = 38.5 bits (88), Expect = 0.012
Identities = 42/181 (23%), Positives = 67/181 (37%), Gaps = 32/181 (17%)
Query: 205 EIVGSIKMRVFLSG-MPELRLGLNDKVLFDNTGRGKSKSVELEDVKFHQCVRL------- 256
++VG++ + L G MP + + L+ + L+D+ H CV
Sbjct: 232 QVVGTVTCKCDLEGIMPNVTISLSLP----------TNGSPLQDILVHPCVTSLDSAILT 281
Query: 257 ---------SRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMI 307
S F F PP F L Y V P++ + E+ RI +
Sbjct: 282 SSSIDAMDDSAFSGPYKFPFTPPLESFNLCFYTSQVPVPPILGFYQMKEEEVQLRITINL 341
Query: 308 KAKSQFKRRSTANNVEIHIPVPNDADSP--KFKTTVGSVKWVPENSEIVWSI-KSFPGGK 364
K K + E HIP N ++KT+ G ++ E S ++W I + FP
Sbjct: 342 KLHESVK--NNFEFCEAHIPFYNRGPITHLEYKTSFGQLEVFREKSLLIWIIGQKFPKSM 399
Query: 365 E 365
E
Sbjct: 400 E 400
>gi|88703051 adaptor-related protein complex 1, sigma 3 subunit
[Homo sapiens]
Length = 154
Score = 32.7 bits (73), Expect = 0.66
Identities = 22/90 (24%), Positives = 40/90 (44%)
Query: 55 VRFMWIKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELL 114
++ ++ ++ +LY + L +++ V++ +YF + E I NF Y +L
Sbjct: 55 LKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFIL 114
Query: 115 DELMDFGYPQTTDSKILQEYITQEGHKLET 144
DE + G Q T KI + I ET
Sbjct: 115 DEFIIGGEIQETSKKIAVKAIEDSDMLQET 144
>gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [Homo
sapiens]
Length = 158
Score = 31.6 bits (70), Expect = 1.5
Identities = 26/129 (20%), Positives = 57/129 (44%), Gaps = 5/129 (3%)
Query: 12 KGKVLICRNYRGDVDMSE---VEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLV 68
+GK+ + + Y D V M +++ ++ + + L ++ ++ ++ +LY
Sbjct: 11 QGKLRLQKWYLATSDKERKKMVRELMQVVLARKPK--MCSFLEWRDLKVVYKRYASLYFC 68
Query: 69 ATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDS 128
+ + +++ V++ +YF + E I NF Y +LDE + G Q T
Sbjct: 69 CAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSK 128
Query: 129 KILQEYITQ 137
K + + I Q
Sbjct: 129 KSVLKAIEQ 137
>gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [Homo
sapiens]
Length = 157
Score = 31.2 bits (69), Expect = 1.9
Identities = 19/83 (22%), Positives = 39/83 (46%)
Query: 55 VRFMWIKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELL 114
++ ++ ++ +LY + + +++ V++ +YF + E I NF Y +L
Sbjct: 54 LKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFIL 113
Query: 115 DELMDFGYPQTTDSKILQEYITQ 137
DE + G Q T K + + I Q
Sbjct: 114 DEFLLGGEVQETSKKNVLKAIEQ 136
>gi|189409104 adaptor-related protein complex 4, sigma 1 subunit
isoform 2 [Homo sapiens]
Length = 144
Score = 31.2 bits (69), Expect = 1.9
Identities = 14/63 (22%), Positives = 32/63 (50%)
Query: 56 RFMWIKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLD 115
+ ++ ++ L++V ++ F++ V+V EYF + E I N ++ +LD
Sbjct: 56 KLIYRQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMFNLDKVHIILD 115
Query: 116 ELM 118
E++
Sbjct: 116 EMV 118
>gi|70906430 adaptor-related protein complex 2, sigma 1 subunit
isoform AP17 [Homo sapiens]
Length = 142
Score = 30.8 bits (68), Expect = 2.5
Identities = 15/53 (28%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Query: 84 LYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFG-YPQTTDSKILQEYI 135
++ V+V +EYF + E + NF +Y ++DE+ G +T+ +K+L++ +
Sbjct: 84 IHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLL 136
>gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]
Length = 1265
Score = 30.4 bits (67), Expect = 3.3
Identities = 41/180 (22%), Positives = 73/180 (40%), Gaps = 24/180 (13%)
Query: 245 LEDVKFHQCV-----RLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHS 299
+E++K +C +++ R S P E+M R+ V+ + +K +
Sbjct: 1059 VEEIKEGECQVKKVNKMTSKSKKRKTSIDPSPESHEVME-RILDSVQGKSTVSEQADKEN 1117
Query: 300 HSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKS 359
+ E M+K K F ++ + EIH PN DS G V S
Sbjct: 1118 NLENEKMVKNKPDFYTKAFRSLSEIH--SPNIQDSSFDSVREGLVP------------LS 1163
Query: 360 FPGGKEYLMRAHFGL---PSVEAEDKEGKPPISVKFEIPYFT-TSGIQVRYLKIIEKSGY 415
GK +++ +F L P+ + D E + +KF++ T SGI R L+ + + +
Sbjct: 1164 VSSGKNVIIKENFALECSPAFQVSDDEHEKMNKMKFKVNRRTQKSGIGDRPLQDLSNTSF 1223
>gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens]
Length = 1261
Score = 30.4 bits (67), Expect = 3.3
Identities = 41/180 (22%), Positives = 73/180 (40%), Gaps = 24/180 (13%)
Query: 245 LEDVKFHQCV-----RLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHS 299
+E++K +C +++ R S P E+M R+ V+ + +K +
Sbjct: 1059 VEEIKEGECQVKKVNKMTSKSKKRKTSIDPSPESHEVME-RILDSVQGKSTVSEQADKEN 1117
Query: 300 HSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKS 359
+ E M+K K F ++ + EIH PN DS G V S
Sbjct: 1118 NLENEKMVKNKPDFYTKAFRSLSEIH--SPNIQDSSFDSVREGLVP------------LS 1163
Query: 360 FPGGKEYLMRAHFGL---PSVEAEDKEGKPPISVKFEIPYFT-TSGIQVRYLKIIEKSGY 415
GK +++ +F L P+ + D E + +KF++ T SGI R L+ + + +
Sbjct: 1164 VSSGKNVIIKENFALECSPAFQVSDDEHEKMNKMKFKVNRRTQKSGIGDRPLQDLSNTSF 1223
>gi|94981553 slow cardiac myosin regulatory light chain 2 [Homo
sapiens]
Length = 166
Score = 30.4 bits (67), Expect = 3.3
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 7/74 (9%)
Query: 205 EIVGSIKMRVFLSGMPELRLG-------LNDKVLFDNTGRGKSKSVELEDVKFHQCVRLS 257
E G I VFL+ E G LN +FD G+G K+ + ++ Q R S
Sbjct: 72 EAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFS 131
Query: 258 RFENDRTISFIPPD 271
+ E D+ + PPD
Sbjct: 132 KEEVDQMFAAFPPD 145
>gi|94557295 mitogen-activated protein kinase 8 interacting protein
3 isoform 2 [Homo sapiens]
Length = 1330
Score = 29.6 bits (65), Expect = 5.6
Identities = 34/151 (22%), Positives = 70/151 (46%), Gaps = 9/151 (5%)
Query: 169 NEVFLDVIESVNLLGKYPGVG-WLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLN 227
+EV DV E +LLG++ G+G +G+ + N +L ++ ++ ++ + + L
Sbjct: 391 SEVIGDVDEGADLLGEFSGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQ--LSGE 448
Query: 228 DKVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKP 287
+VL K V+LE+ L R +++ I+ P E E +S L T
Sbjct: 449 QEVLRGELEAAKQAKVKLENRIKELEEELKRVKSEAIIARREPKEEAEDVSSYLCTESDK 508
Query: 288 LIWIESVIEKHSHSRIEY--MIKAKSQFKRR 316
+ + ++ +R+E ++ ++Q+K R
Sbjct: 509 I----PMAQRRRFTRVEMARVLMERNQYKER 535
>gi|11038643 adaptor-related protein complex 2, sigma 1 subunit
isoform AP17delta [Homo sapiens]
Length = 104
Score = 29.6 bits (65), Expect = 5.6
Identities = 15/49 (30%), Positives = 30/49 (61%), Gaps = 1/49 (2%)
Query: 88 VQVFSEYFKELEEESIRDNFVIIYELLDELMDFG-YPQTTDSKILQEYI 135
V+V +EYF + E + NF +Y ++DE+ G +T+ +K+L++ +
Sbjct: 50 VEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLL 98
>gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]
Length = 222
Score = 29.3 bits (64), Expect = 7.3
Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 31/158 (19%)
Query: 6 VYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRF------MW 59
+Y D+K + LI G D++E+ +P+ +E++ ++ I R+ +
Sbjct: 81 LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVL 140
Query: 60 IKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMD 119
H YLV A +SLV LY Y +EL + S+ NF ++ L + +
Sbjct: 141 QSHGQDYLVGNKLSRADISLV-ELLY--------YVEEL-DSSLISNFPLLKALKTRISN 190
Query: 120 FGYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAV 157
T K LQ G+PR P A+
Sbjct: 191 L----PTVKKFLQ-----------PGSPRKPPADAKAL 213
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 29.3 bits (64), Expect = 7.3
Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 12/72 (16%)
Query: 356 SIKSFPGGKEYLMRAHFGLP----------SVEAEDKEGKPPISVKFEIPYFTTSGIQVR 405
+++SFPG KEY ++A G+ +++A+DK G PP ++ + T+ +
Sbjct: 305 TVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDK-GTPPQFSSVKVIHVTSPQFKAG 363
Query: 406 YLKIIEKSGYQA 417
+K EK Y+A
Sbjct: 364 PVK-FEKDVYRA 374
>gi|45439365 transmembrane protein 180 [Homo sapiens]
Length = 517
Score = 29.3 bits (64), Expect = 7.3
Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 2/60 (3%)
Query: 172 FLDVIESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVL 231
++D SV + K W+G TV N L + G + R FLS P GL+ + +
Sbjct: 37 YVDTFVSVYKINKM--AFWVGETVFLLWNSLNDPLFGWLSDRQFLSSQPRSGAGLSSRAV 94
>gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens]
Length = 1260
Score = 28.9 bits (63), Expect = 9.6
Identities = 35/158 (22%), Positives = 63/158 (39%), Gaps = 23/158 (14%)
Query: 245 LEDVKFHQCV-----RLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHS 299
+E++K +C +++ R S P E+M R+ V+ + +K +
Sbjct: 1059 VEEIKEGECQVKKVNKMTSKSKKRKTSIDPSPESHEVME-RILDSVQGKSTVSEQADKEN 1117
Query: 300 HSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKS 359
+ E M+K K F ++ + EIH PN DS G V S
Sbjct: 1118 NLENEKMVKNKPDFYTKAFRSLSEIH--SPNIQDSSFDSVREGLVP------------LS 1163
Query: 360 FPGGKEYLMRAHFGL---PSVEAEDKEGKPPISVKFEI 394
GK +++ +F L P+ + D E + +KF++
Sbjct: 1164 VSSGKNVIIKENFALECSPAFQVSDDEHEKMNKMKFKV 1201
>gi|119874201 furry-like [Homo sapiens]
Length = 3013
Score = 28.9 bits (63), Expect = 9.6
Identities = 30/158 (18%), Positives = 61/158 (38%), Gaps = 35/158 (22%)
Query: 190 WLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTG-RGKSKSVELEDV 248
+LG+ +A N LR ++G D G R +S ++++ D
Sbjct: 1930 YLGYNSNARSNSLRLSLIG------------------------DRRGDRRRSNTLDIMDG 1965
Query: 249 KFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIK 308
+ + L+R R++S + G +++ S T++ I+ + S EY++
Sbjct: 1966 RINHSSSLAR---TRSLSSLREKGMYDVQSTTEPTNLMATIFWIAASLLESDYEYEYLLA 2022
Query: 309 AKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKW 346
+ N + IH+P+ K + +KW
Sbjct: 2023 LR-------LLNKLLIHLPLDKSESREKIENVQSKLKW 2053
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,900,265
Number of Sequences: 37866
Number of extensions: 767208
Number of successful extensions: 1665
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1596
Number of HSP's gapped (non-prelim): 41
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.