Guide to the Human Genome
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Search of human proteins with 194306541

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194306541 oxidation resistance 1 isoform 1 [Homo sapiens]
         (846 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194306541 oxidation resistance 1 isoform 1 [Homo sapiens]         1699   0.0  
gi|194306543 oxidation resistance 1 isoform 2 [Homo sapiens]         1553   0.0  
gi|170932526 nuclear receptor coactivator 7 isoform 2 [Homo sapi...   340   2e-93
gi|170932524 nuclear receptor coactivator 7 isoform 1 [Homo sapi...   340   2e-93
gi|62909985 hypothetical protein LOC140711 [Homo sapiens]             205   1e-52
gi|205360930 hypothetical protein LOC57707 [Homo sapiens]              78   3e-14
gi|89886453 TBC1 domain family, member 24 [Homo sapiens]               77   9e-14
gi|93204867 G protein-coupled receptor 158 [Homo sapiens]              45   4e-04
gi|56676335 RAP1 interacting factor 1 [Homo sapiens]                   44   8e-04
gi|124249396 coiled-coil domain containing 30 [Homo sapiens]           43   0.001
gi|60097902 filaggrin [Homo sapiens]                                   43   0.001
gi|116805342 human immunodeficiency virus type I enhancer bindin...    41   0.004
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           41   0.004
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    41   0.005
gi|62244004 modulator of estrogen induced transcription isoform ...    40   0.007
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    40   0.009
gi|87299628 biorientation of chromosomes in cell division 1-like...    40   0.009
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                40   0.012
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                40   0.012
gi|71061468 centromere protein E [Homo sapiens]                        40   0.012
gi|117414154 sodium channel associated protein 2 isoform b [Homo...    39   0.016
gi|117414162 sodium channel associated protein 2 isoform a [Homo...    39   0.016
gi|217330641 IWS1 homolog [Homo sapiens]                               39   0.020
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi...    39   0.020
gi|119226220 membrane-spanning 4-domains, subfamily A, member 14...    39   0.020
gi|119226217 membrane-spanning 4-domains, subfamily A, member 14...    39   0.020
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       39   0.020
gi|8922940 gamma-taxilin [Homo sapiens]                                39   0.026
gi|150170670 piccolo isoform 2 [Homo sapiens]                          39   0.026
gi|150378539 piccolo isoform 1 [Homo sapiens]                          39   0.026

>gi|194306541 oxidation resistance 1 isoform 1 [Homo sapiens]
          Length = 846

 Score = 1699 bits (4399), Expect = 0.0
 Identities = 846/846 (100%), Positives = 846/846 (100%)

Query: 1   MSVSNLSWLKKKSQSVDINAPGFNPLAGAGKQTPQASKPPAPKTPIIEEEQNNAANTQKH 60
           MSVSNLSWLKKKSQSVDINAPGFNPLAGAGKQTPQASKPPAPKTPIIEEEQNNAANTQKH
Sbjct: 1   MSVSNLSWLKKKSQSVDINAPGFNPLAGAGKQTPQASKPPAPKTPIIEEEQNNAANTQKH 60

Query: 61  PSRRSELKRFYTIDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPN 120
           PSRRSELKRFYTIDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPN
Sbjct: 61  PSRRSELKRFYTIDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPN 120

Query: 121 ELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVH 180
           ELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVH
Sbjct: 121 ELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVH 180

Query: 181 PTEATPSSTFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIM 240
           PTEATPSSTFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIM
Sbjct: 181 PTEATPSSTFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIM 240

Query: 241 FDPHKNDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHS 300
           FDPHKNDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHS
Sbjct: 241 FDPHKNDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHS 300

Query: 301 KKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQD 360
           KKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQD
Sbjct: 301 KKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQD 360

Query: 361 KSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMA 420
           KSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMA
Sbjct: 361 KSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMA 420

Query: 421 IKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQ 480
           IKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQ
Sbjct: 421 IKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQ 480

Query: 481 SVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHI 540
           SVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHI
Sbjct: 481 SVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHI 540

Query: 541 ESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTD 600
           ESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTD
Sbjct: 541 ESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTD 600

Query: 601 HLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDIN 660
           HLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDIN
Sbjct: 601 HLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDIN 660

Query: 661 SKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTS 720
           SKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTS
Sbjct: 661 SKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTS 720

Query: 721 LKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFK 780
           LKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFK
Sbjct: 721 LKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFK 780

Query: 781 WTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDI 840
           WTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDI
Sbjct: 781 WTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDI 840

Query: 841 EIWAFE 846
           EIWAFE
Sbjct: 841 EIWAFE 846


>gi|194306543 oxidation resistance 1 isoform 2 [Homo sapiens]
          Length = 839

 Score = 1553 bits (4020), Expect = 0.0
 Identities = 773/773 (100%), Positives = 773/773 (100%)

Query: 74  DTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAV 133
           DTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAV
Sbjct: 67  DTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAV 126

Query: 134 VTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGI 193
           VTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGI
Sbjct: 127 VTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGI 186

Query: 194 RPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQEN 253
           RPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQEN
Sbjct: 187 RPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQEN 246

Query: 254 GCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDS 313
           GCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDS
Sbjct: 247 GCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDS 306

Query: 314 RIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTV 373
           RIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTV
Sbjct: 307 RIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTV 366

Query: 374 NQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGI 433
           NQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGI
Sbjct: 367 NQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGI 426

Query: 434 SGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQ 493
           SGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQ
Sbjct: 427 SGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQ 486

Query: 494 DSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRHR 553
           DSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRHR
Sbjct: 487 DSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRHR 546

Query: 554 LHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEI 613
           LHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEI
Sbjct: 547 LHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEI 606

Query: 614 YAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDINSKQVATVKADLES 673
           YAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDINSKQVATVKADLES
Sbjct: 607 YAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDINSKQVATVKADLES 666

Query: 674 ESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDT 733
           ESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDT
Sbjct: 667 ESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDT 726

Query: 734 PVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDM 793
           PVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDM
Sbjct: 727 PVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDM 786

Query: 794 DSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE 846
           DSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE
Sbjct: 787 DSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE 839


>gi|170932526 nuclear receptor coactivator 7 isoform 2 [Homo
           sapiens]
          Length = 931

 Score =  340 bits (873), Expect = 2e-93
 Identities = 163/307 (53%), Positives = 210/307 (68%), Gaps = 5/307 (1%)

Query: 540 IESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERT 599
           IE     KE++      FLC++VGKPMRK+F +  +A +QQY +R K+ EYWFAVP+ER 
Sbjct: 630 IEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERV 689

Query: 600 DHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDI 659
           DHLY FF+QWSP++Y +D     +E GF+VV+K EE   I++  ++   + WEI T E+ 
Sbjct: 690 DHLYTFFVQWSPDVYGKDA----KEQGFVVVEK-EELNMIDNFFSEPTTKSWEIITVEEA 744

Query: 660 NSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGT 719
             ++      + E E   P L   S LL    IE+L + LP R  GYPW L Y T +HGT
Sbjct: 745 KRRKSTCSYYEDEDEEVLPVLRPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGT 804

Query: 720 SLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVF 779
           SLKTLYR    LD+PVL+VIKD D Q+FGA A+ P K SD +YGTGETF++TF P F+VF
Sbjct: 805 SLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVF 864

Query: 780 KWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQD 839
           KW+G+N +FI GD+ SL  GGGGG F LWLD DLYHGRS+SC TF N  LSKKEDF +QD
Sbjct: 865 KWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQD 924

Query: 840 IEIWAFE 846
           +E+WAF+
Sbjct: 925 LEVWAFD 931



 Score =  257 bits (656), Expect = 4e-68
 Identities = 162/378 (42%), Positives = 215/378 (56%), Gaps = 33/378 (8%)

Query: 49  EEQNNAANTQKHPSRRSELKRFYTIDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSL 108
           +E+    + Q    RR+ELKR+Y+ID  Q KT DKK+ ++M  QKP GT+EYT  ++D+L
Sbjct: 66  DEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKE-KKMVVQKPHGTMEYTAGNQDTL 124

Query: 109 NSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSE 168
           NSIALKF+ TPN+LV+LNKLF+  +V GQVL+VPD    SS     S SP + +SP+SS+
Sbjct: 125 NSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSPSSSD 184

Query: 169 AEFDKTTNPDVHPTEATPSSTFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTV 228
           AE+DK  + D+      P          RV+SSTSEE+E    KFLK+NC+Y T GKG V
Sbjct: 185 AEYDKLPDADLARKALKPIE--------RVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVV 236

Query: 229 SGVLLVTPNNIMFDPHKNDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPID 288
            GV++VTPNNIMFDPHK+DPLV ENGCEEYG++CPMEEV+S A+Y +I   KIK++LP  
Sbjct: 237 GGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSP 296

Query: 289 ---IDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTA---PRSTEESLSEDVFTES 342
               D  S +D     K    N E+     R    +   T+   P    E  +    T+ 
Sbjct: 297 GEWEDLASEKDINPFSKFKSINKEK-----RQQNGEKIMTSDSRPIVPLEKSTGHTPTKP 351

Query: 343 ELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKS--ESTGTPGHLRS---- 396
             S + E+L   D      SS  +S    TV +   E     S  EST     L      
Sbjct: 352 SGSSVSEKLKKLD------SSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDF 405

Query: 397 -DTEHSTNEVGTLCHKTD 413
            D E  +++ G   HK D
Sbjct: 406 VDLEELSSQTGGGMHKKD 423


>gi|170932524 nuclear receptor coactivator 7 isoform 1 [Homo
           sapiens]
          Length = 942

 Score =  340 bits (873), Expect = 2e-93
 Identities = 163/307 (53%), Positives = 210/307 (68%), Gaps = 5/307 (1%)

Query: 540 IESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERT 599
           IE     KE++      FLC++VGKPMRK+F +  +A +QQY +R K+ EYWFAVP+ER 
Sbjct: 641 IEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERV 700

Query: 600 DHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDI 659
           DHLY FF+QWSP++Y +D     +E GF+VV+K EE   I++  ++   + WEI T E+ 
Sbjct: 701 DHLYTFFVQWSPDVYGKDA----KEQGFVVVEK-EELNMIDNFFSEPTTKSWEIITVEEA 755

Query: 660 NSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGT 719
             ++      + E E   P L   S LL    IE+L + LP R  GYPW L Y T +HGT
Sbjct: 756 KRRKSTCSYYEDEDEEVLPVLRPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGT 815

Query: 720 SLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVF 779
           SLKTLYR    LD+PVL+VIKD D Q+FGA A+ P K SD +YGTGETF++TF P F+VF
Sbjct: 816 SLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVF 875

Query: 780 KWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQD 839
           KW+G+N +FI GD+ SL  GGGGG F LWLD DLYHGRS+SC TF N  LSKKEDF +QD
Sbjct: 876 KWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQD 935

Query: 840 IEIWAFE 846
           +E+WAF+
Sbjct: 936 LEVWAFD 942



 Score =  258 bits (659), Expect = 2e-68
 Identities = 132/243 (54%), Positives = 173/243 (71%), Gaps = 9/243 (3%)

Query: 49  EEQNNAANTQKHPSRRSELKRFYTIDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSL 108
           +E+    + Q    RR+ELKR+Y+ID  Q KT DKK+ ++M  QKP GT+EYT  ++D+L
Sbjct: 66  DEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKE-KKMVVQKPHGTMEYTAGNQDTL 124

Query: 109 NSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSE 168
           NSIALKF+ TPN+LV+LNKLF+  +V GQVL+VPD    SS     S SP + +SP+SS+
Sbjct: 125 NSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSPSSSD 184

Query: 169 AEFDKTTNPDVHPTEATPSSTFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTV 228
           AE+DK  + D+      P          RV+SSTSEE+E    KFLK+NC+Y T GKG V
Sbjct: 185 AEYDKLPDADLARKALKPIE--------RVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVV 236

Query: 229 SGVLLVTPNNIMFDPHKNDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPID 288
            GV++VTPNNIMFDPHK+DPLV ENGCEEYG++CPMEEV+S A+Y +I   KIK++LP D
Sbjct: 237 GGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSD 296

Query: 289 IDQ 291
           + Q
Sbjct: 297 LPQ 299


>gi|62909985 hypothetical protein LOC140711 [Homo sapiens]
          Length = 215

 Score =  205 bits (522), Expect = 1e-52
 Identities = 91/187 (48%), Positives = 128/187 (68%)

Query: 657 EDINSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGK 716
           E+   ++ A   A    +   P L++ S++L   +I +L+ H PPR  G+PW+LV+ T +
Sbjct: 26  EEEEEEEAAPDPAAAPEDPTVPQLTEASQVLSASEIRQLSFHFPPRVTGHPWSLVFCTSR 85

Query: 717 HGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEF 776
            G SL++LYR M G   PVL+V++D DGQ+FGA +S  +++S GFYGTGETF+F+F P+ 
Sbjct: 86  DGFSLQSLYRRMEGCSGPVLLVLRDQDGQIFGAFSSSAIRLSKGFYGTGETFLFSFSPQL 145

Query: 777 EVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFF 836
           +VFKWTG N FF+KGD+DSL  G G G F LWLDGDL+ G S  C TF N  L+++E F 
Sbjct: 146 KVFKWTGSNSFFVKGDLDSLMMGSGSGRFGLWLDGDLFRGGSSPCPTFNNEVLARQEQFC 205

Query: 837 IQDIEIW 843
           IQ++E W
Sbjct: 206 IQELEAW 212


>gi|205360930 hypothetical protein LOC57707 [Homo sapiens]
          Length = 456

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 50/153 (32%), Positives = 72/153 (47%), Gaps = 10/153 (6%)

Query: 701 PRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDG 760
           PR   + W L++ +  HG S   L   +T    P + V++D D  VFG  AS   +V   
Sbjct: 259 PREQRHRWCLLFSSELHGHSFSQLCGHITHRG-PCVAVLEDHDKHVFGGFASCSWEVKPQ 317

Query: 761 FYGTGETFVFTFCPEFEVFKWTGDN---MFFIKGDM---DSLAFGGGGGEFALWLDGDLY 814
           F G    F+F+ CP   V+  TG N   M+   G     + L  GG    F LW+D D  
Sbjct: 318 FQGDNRCFLFSICPSMAVYTHTGYNDHYMYLNHGQQTIPNGLGMGGQHNYFGLWVDVDFG 377

Query: 815 HGRSH---SCKTFGNRTLSKKEDFFIQDIEIWA 844
            G S    +C T+ +  LS +E+F    +E+WA
Sbjct: 378 KGHSRAKPTCTTYNSPQLSAQENFQFDKMEVWA 410


>gi|89886453 TBC1 domain family, member 24 [Homo sapiens]
          Length = 553

 Score = 76.6 bits (187), Expect = 9e-14
 Identities = 68/257 (26%), Positives = 108/257 (42%), Gaps = 67/257 (26%)

Query: 643 SNQAAAREWEITTREDINSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPR 702
           +N+ A ++  IT ++      +A     + +E+FR      SE++   ++  +   +P R
Sbjct: 306 ANEKALKQKGITVKQKRQFVHLA-----VHAENFR------SEIVSVREMRDIWSWVPER 354

Query: 703 TIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSD--- 759
                  L++ + +HG SL   Y    G + P L++IK +  +V GA  S      +   
Sbjct: 355 FALCQPLLLFSSLQHGYSLARFYFQCEGHE-PTLLLIKTTQKEVCGAYLSTDWSERNKFG 413

Query: 760 ---GFYGTGETFVFTFCPEFEVFKWT------------------------------GDNM 786
              GF+GTGE FVF   PE + ++W                                D +
Sbjct: 414 GKLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRL 473

Query: 787 -----------------FFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTL 829
                             F+ G  D L  GGGGG+ AL++DGDL  GR+  C TF N+ L
Sbjct: 474 SPFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQ-ALYIDGDLNRGRTSHCDTFNNQPL 532

Query: 830 SKKEDFFIQDIEIWAFE 846
              E+F I  +E W F+
Sbjct: 533 C-SENFLIAAVEAWGFQ 548


>gi|93204867 G protein-coupled receptor 158 [Homo sapiens]
          Length = 1215

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 50/212 (23%), Positives = 83/212 (39%), Gaps = 23/212 (10%)

Query: 315 IRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVN 374
           IR    +S+    +S EE+L   VF+  +     + +   D+  +  S    S+  +T  
Sbjct: 788 IRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHV--RDQTEESSSLPTESQEEETTE 845

Query: 375 QAEVESLTVKSESTGTPGHLRSDTE-HSTNEVGTLCHKTDLNNLEMAIKE-----DQIAD 428
            + +ESL+ K  +      L+ D+E  ST  V  +C     +NL    K        +  
Sbjct: 846 NSTLESLSGKKLTQ----KLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQK 901

Query: 429 NFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQG 488
           +   I+  KE +  + G +             EE  K   P  +  E  +  S +   + 
Sbjct: 902 SLSVIASAKEKTLGLAGKTQTAGV--------EERTKSQKPLPKDKETNRNHSNSDNTET 953

Query: 489 KEQNQDSQTEAEELRKLWKTHTMQQTKQQREN 520
           K+    +   AEE RK  K+  M   KQQR N
Sbjct: 954 KDPAPQNSNPAEEPRKPQKSGIM---KQQRVN 982


>gi|56676335 RAP1 interacting factor 1 [Homo sapiens]
          Length = 2472

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 50/237 (21%), Positives = 102/237 (43%), Gaps = 28/237 (11%)

Query: 302  KMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVF---------TESELSPIREELV 352
            K+T SN E+  +   + GN+++      T+  +SE+           +E++ + +  + V
Sbjct: 1905 KVTESNLEKAKTMELNVGNEASFHGQERTKTGISEEAAIEENKRNDDSEADTAKLNAKEV 1964

Query: 353  SSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKT 412
            +++E   D S   ++  V+   Q E+   T   E  G  G+  SD  HS+ E  T     
Sbjct: 1965 ATEEFNSDISLSDNTTPVKLNAQTEISEQTAAGELDG--GNDVSDL-HSSEETNTKMK-- 2019

Query: 413  DLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGE 472
              NN EM I E        G        T  +G + + S   E   +   ++ +N  C +
Sbjct: 2020 --NNEEMMIGEAMAETGHDG-------ETENEGITTKTSKPDEAETNMLTAEMDNFVC-D 2069

Query: 473  TAEFKQKQSV---NKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQ 526
            T E   ++ +   NK +   E ++ S+ + +  + + ++  +Q+     + +++ SQ
Sbjct: 2070 TVEMSTEEGIIDANKTETNTEYSK-SEEKLDNNQMVMESDILQEDHHTSQKVEEPSQ 2125


>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
          Length = 783

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 92/435 (21%), Positives = 161/435 (37%), Gaps = 76/435 (17%)

Query: 205 EEEAFTEKFLKINCKYITSGKGTVSGVL----LVTPNNIMFDPHKNDPLVQ---ENGCEE 257
           E      K LK++ ++      T+ G      L+T  N   DP  N+P+++   ++  EE
Sbjct: 78  ENSELETKVLKLSQEFAQLNHFTLGGKTAPSNLITSENTCKDPESNEPILETEIQSRKEE 137

Query: 258 YGIMCPMEEVMSAAMYKEILDSKIKE-SLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIR 316
              +CP    +     KEI +  +KE S P +                    EE   + R
Sbjct: 138 TEELCPK---LGERKQKEIPEESVKEGSFPRE-----------------GQKEEGSQQNR 177

Query: 317 DAGNDSASTAPRSTEESLSEDVFTESELSPIREELVS-SDELRQDKSSGASSESVQTVNQ 375
           D             EE   +      E+  +REEL   +  L Q +SSG SS+     + 
Sbjct: 178 D----------MKDEEKEQQLTMKPEEIVRLREELSHINQSLLQSQSSGDSSDDSGAQHP 227

Query: 376 AEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISG 435
           +  E L    +      H       + + +  LC+  +    E+  +  Q  D  Q  S 
Sbjct: 228 SSGEKLKYNQQGEVQQLH------QNLHRLQILCNSAE---NELRYERGQNLDLKQHNSL 278

Query: 436 PKEDSTSIK-----------GNSDQDSFLHENSLHQEESQKE----------NMPCGETA 474
            +E++  IK            ++   S L     H ++  KE          ++      
Sbjct: 279 LQEENIKIKIELKHAQQKLLDSTKMCSSLTAEYKHCQQKIKELELEVLKHTQSIKSQNNL 338

Query: 475 EFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQ-RENIQQVSQKEAKHKI 533
           + K  Q  +K    +E+  D Q + E   K+  T T    KQQ  E I++ +Q EAK K 
Sbjct: 339 QEKLVQEKSKVADAEEKILDLQRKLEHAHKVCLTDTCISEKQQLEEKIKEATQNEAKVKQ 398

Query: 534 TSADGHIESSALLKE-KQRHRLHKFL-----CLRVGKPMRKTFVSQASATMQQYAQRDKK 587
              +   +   L +   + HR  + L      L +    +++ + Q  A ++Q     +K
Sbjct: 399 QYQEEQQKRKLLYQNVDELHRQVRTLQDKENLLEMTCSQQQSRIQQQEALLKQLENEKRK 458

Query: 588 HEYWFAVPQERTDHL 602
           ++      QE ++ L
Sbjct: 459 YDEHVKSNQELSEKL 473


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 66/299 (22%), Positives = 114/299 (38%), Gaps = 49/299 (16%)

Query: 300  SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTES-----ELSPIREELVSS 354
            S + +G    +  S +RD+G+  +S +  S  E  SED  T+S     +  P ++   S 
Sbjct: 3636 SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQ---SH 3692

Query: 355  DELRQDKSSGASSES------VQTVNQAEVESLTVKSESTGTPG----HLRSDTEHSTNE 404
             E  + +S+G S  S      V T  Q+E         + G  G      R  + HS ++
Sbjct: 3693 QESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQ 3752

Query: 405  VG---TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQ------------ 449
             G      H             +Q  D   G SG     T+ +G SD             
Sbjct: 3753 EGQDTIRGHPGSRRGGRQGSYHEQSVDR-SGHSGSHHSHTTSQGRSDASHGQSGSRSASR 3811

Query: 450  ---------DSFLHENSLHQEES-QKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEA 499
                     D   H  S H E S Q ++    ++ + +   S    +QG   +QDS +EA
Sbjct: 3812 ETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEA 3871

Query: 500  --EELRKLWKTHTMQQTKQQRENIQQVSQKE-AKHKITSADGHIESSALLKEKQRHRLH 555
              E+  +  ++ +       RE  +  S+   + H+ T++  H++SS +  +    + H
Sbjct: 3872 YPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTAS--HVQSSPVQSDSSTAKEH 3928



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 58/272 (21%), Positives = 94/272 (34%), Gaps = 25/272 (9%)

Query: 300  SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTES-----ELSPIREELVSS 354
            S + +G    +  S +RD+G+  +S +  S  E  SED  T+S     +  P ++    S
Sbjct: 2340 SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQES 2399

Query: 355  DELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG-------HLRSDTEHSTNEVGT 407
               R    SG S   +  V+  E          T T G         R  + HST++ G 
Sbjct: 2400 TRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQ 2459

Query: 408  LC---HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQ 464
                 H    +        +Q+ D   G SG     T+ +G SD  S  H  S       
Sbjct: 2460 DTIHGHPGSSSGGRQGSHYEQLVDR-SGHSGSHHSHTTSQGRSDA-SHGHSGSRSASRQT 2517

Query: 465  KENMPCGETAEFK----QKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQREN 520
            + +   G+ +        + S      G  Q    Q+E     + W +   Q +  Q  +
Sbjct: 2518 RNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHS 2577

Query: 521  IQQVSQKEAKHKITSADGHIESSALLKEKQRH 552
                   E      S + H  +   L++  RH
Sbjct: 2578 ----EDSERWSGSASRNHHGSAQEQLRDGSRH 2605



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 55/278 (19%), Positives = 97/278 (34%), Gaps = 47/278 (16%)

Query: 300  SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTES-----ELSPIREELVSS 354
            S + +G    +  S +RD+G+  +S +  +  E  SED  T+S     +  P ++    S
Sbjct: 1367 SSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKES 1426

Query: 355  DELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG-------HLRSDTEHSTNEVG- 406
               +  +SSG S   +  V+  E    T    +  T G         R+ + HS ++ G 
Sbjct: 1427 ARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQ 1486

Query: 407  --TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQ--------------- 449
                 H             +Q  D   G SG     T+ +G SD                
Sbjct: 1487 DTIRGHPGSSRGGRQGSYHEQSVDR-SGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTR 1545

Query: 450  ------DSFLHENSLHQEESQK----------ENMPCGETAEFKQKQSVNKGKQGKEQNQ 493
                  D   H  S H E S +          +    G     +Q  SV++ +  +  ++
Sbjct: 1546 NEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSE 1605

Query: 494  DSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKH 531
            DS+  +E   +       +Q++    N +   +  A H
Sbjct: 1606 DSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASH 1643



 Score = 37.0 bits (84), Expect = 0.077
 Identities = 58/272 (21%), Positives = 99/272 (36%), Gaps = 46/272 (16%)

Query: 300  SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQ 359
            S + +G    +  S +RD+G+   S +  S  E  SED  T+S  +    +  S  +  Q
Sbjct: 2988 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSA--HGQAGSHQQSHQ 3045

Query: 360  DKSSGASSES----------VQTVNQAEVESLTVKSESTGTPG----HLRSDTEHSTNEV 405
            + + G S E+          V T  Q+E         + G  G      +  + HS ++ 
Sbjct: 3046 ESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQY 3105

Query: 406  G---TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQ------------- 449
            G      H             +   D+  G SG     T+ +G SD              
Sbjct: 3106 GQDTIRGHPGSSRGGRQGYHHEHSVDS-SGHSGSHHSHTTSQGRSDASRGQSGSRSASRT 3164

Query: 450  --------DSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKG-KQGKEQNQDSQTEA- 499
                    DS  H  S H E S   ++     A   Q +   +  +QG   +QDS +E  
Sbjct: 3165 TRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGH 3224

Query: 500  EELRKLWKTHTMQQTKQQRENIQQVSQKEAKH 531
             E  + W   +   ++  R ++Q+ S+  ++H
Sbjct: 3225 SEDSERW---SGSASRNHRGSVQEQSRHGSRH 3253



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 55/270 (20%), Positives = 96/270 (35%), Gaps = 42/270 (15%)

Query: 300 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESEL--SPIREELVSSDEL 357
           S + +G+   +  S +RD+G+  +S +  +  E  SED  T+S            S  E 
Sbjct: 719 SSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQES 778

Query: 358 RQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG----------HLRSDTEHSTNEVG- 406
            +D+S   S  S   + Q      +  S     P             R ++ HS ++ G 
Sbjct: 779 ARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQ 838

Query: 407 --TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSD---------------- 448
                H             +Q  D   G SG     T+ +G SD                
Sbjct: 839 DTIRGHPGSSRRGRQGSHHEQSVDR-SGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 897

Query: 449 -----QDSFLHENSLHQEESQKENMP-CGETAEFKQKQSVNKGKQGKEQNQDSQTEA-EE 501
                +D   H  S H E S   ++    +  + + + S    +QG   +QDS +E   E
Sbjct: 898 NEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSE 957

Query: 502 LRKLWKTHTMQQTKQQRENIQQVSQKEAKH 531
             + W   +   ++  R + Q+ S+  ++H
Sbjct: 958 DSERW---SGSASRNHRGSAQEQSRHGSRH 984



 Score = 34.3 bits (77), Expect = 0.50
 Identities = 61/285 (21%), Positives = 101/285 (35%), Gaps = 41/285 (14%)

Query: 300  SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE--ELVSSDEL 357
            S + +G    +  S +RD+G+  +S +  S  E  SE+  T+S     ++     S  E 
Sbjct: 1043 SSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQES 1102

Query: 358  RQDKSSGASSES------VQTVNQAEVESLTVKSESTGTPG----HLRSDTEHSTNEVG- 406
             +D S G S  S      V T  Q+E      ++ +    G      R  + HS ++ G 
Sbjct: 1103 ARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQ 1162

Query: 407  --TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQ--------------- 449
                 H             +Q  D   G SG     T+ +G SD                
Sbjct: 1163 DTIRAHPGSRRGGRQGSHHEQSVDR-SGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTR 1221

Query: 450  ------DSFLHENSLHQE-ESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTE--AE 500
                  D   H  S H E  S  ++    +  + +   S     QG   +QDS +E  ++
Sbjct: 1222 KDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSD 1281

Query: 501  ELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSAD-GHIESSA 544
            +  +L  + +       RE  +  S+    H+   A  GH   S+
Sbjct: 1282 DSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSS 1326



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 38/164 (23%), Positives = 62/164 (37%), Gaps = 16/164 (9%)

Query: 300  SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTES-----ELSPIREELVSS 354
            S + +G    +  S +RD+G+   S +  S  E  SED  T+S     +  P ++    S
Sbjct: 2016 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKES 2075

Query: 355  DELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG-------HLRSDTEHSTNEVG- 406
               +  +SSG S   +  V+  E    T    +  T G         +  + HS ++ G 
Sbjct: 2076 ARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQ 2135

Query: 407  --TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSD 448
                 H            ++Q  D   G SG     T+ +G SD
Sbjct: 2136 DTIRGHPGPSRGGRQGSHQEQSVDR-SGHSGSHHSHTTSQGRSD 2178



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 59/285 (20%), Positives = 101/285 (35%), Gaps = 45/285 (15%)

Query: 300  SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQ 359
            S + +G    +  S +RD+G+   S +  S  E  SED  T+S  +    +  S  +  Q
Sbjct: 2664 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSA--HGQAGSHQQSHQ 2721

Query: 360  DKSSGASSES----------VQTVNQAEVESLTVKSESTGTPG----HLRSDTEHSTNEV 405
            + + G S E+          V T  Q+E         + G  G      +  + HS ++ 
Sbjct: 2722 ESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQD 2781

Query: 406  G---TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQ------------- 449
            G      H             +   D+  G SG     T+ +G SD              
Sbjct: 2782 GQDTIRGHPGSSRGGRQGYHHEHSVDS-SGHSGSHHSHTTSQGRSDASRGQSGSRSASRT 2840

Query: 450  --------DSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKG-KQGKEQNQDSQTE-- 498
                    D   H  S H E S   ++     A   Q +   +  +QG   +QDS +E  
Sbjct: 2841 TRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGH 2900

Query: 499  AEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESS 543
            +E+  +   + +       +E ++  S+    H+   A GH  S+
Sbjct: 2901 SEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRA-GHGHSA 2944



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 60/282 (21%), Positives = 101/282 (35%), Gaps = 50/282 (17%)

Query: 312  DSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSES-- 369
            DSR   +    AS +   +EES ++ V    +  P ++   S  E  +D+S G S  S  
Sbjct: 3329 DSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQ---SHQESARDRSGGRSGRSGS 3385

Query: 370  ----VQTVNQAEVESLTVKSESTGTPG----HLRSDTEHSTNEVG---TLCHKTDLNNLE 418
                V T  Q+E      ++ +    G      R  + HS ++ G      H        
Sbjct: 3386 FLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGR 3445

Query: 419  MAIKEDQIADNFQGISGPKEDSTSIKGNSDQ---------------------DSFLHENS 457
                 +Q  D   G SG     T+ +G SD                      D   H  S
Sbjct: 3446 QGSHYEQSVDR-SGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWS 3504

Query: 458  LHQEES----QKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQ 513
             H E S       +   G+      + S N+G     Q+ DSQ  +E+  + W   +   
Sbjct: 3505 HHHEASTQADSSRHSQSGQGQSAGPRTSRNQG-SSVSQDSDSQGHSEDSER-W---SGSA 3559

Query: 514  TKQQRENIQQVSQKEAKHKITSAD---GHIESSALLKEKQRH 552
            ++  R + Q+ S+  ++H  +  +   GH  S+   ++   H
Sbjct: 3560 SRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTH 3601



 Score = 30.4 bits (67), Expect = 7.2
 Identities = 61/297 (20%), Positives = 103/297 (34%), Gaps = 50/297 (16%)

Query: 300 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTES-----ELSPIREELVSS 354
           S + + +   +  S + D G+  +S +  S  E  SE+  T+S     +    ++    S
Sbjct: 394 SSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQES 453

Query: 355 DELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG-------HLRSDTEHSTNEVG- 406
              R  + SG S  S+  V+  E          T T G         R  + HS ++ G 
Sbjct: 454 TRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQ 513

Query: 407 -TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQ---------------- 449
            T+      +         + + N  G SG     T+ +G SD                 
Sbjct: 514 DTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRN 573

Query: 450 -----DSFLHENSLHQEESQK----ENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAE 500
                D   H  S H E S +     +   G+      + S N+G     Q+ DSQ  +E
Sbjct: 574 EEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQG-SSVSQDSDSQGHSE 632

Query: 501 ELRKLW-----KTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRH 552
           +  + W     + H     +Q R+  +      + H+  +  GH   S+  K   RH
Sbjct: 633 DSER-WSGSASRNHHGSAQEQSRDGSR---HPRSHHEDRAGHGHSADSS-RKSGTRH 684



 Score = 30.0 bits (66), Expect = 9.4
 Identities = 52/258 (20%), Positives = 93/258 (36%), Gaps = 39/258 (15%)

Query: 304  TGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTES-----ELSPIREELVSSDELR 358
            +G+   +  S + D+GN  +S +  S  E  SE+  T+S     +  P ++    S   +
Sbjct: 1695 SGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQ 1754

Query: 359  QDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLE 418
              + SG S   +  V+  E            T G  RS  E + +           ++  
Sbjct: 1755 SGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARD-----------SSRH 1803

Query: 419  MAIKEDQIADNFQGISGPK---------EDSTSIKGNSDQDSFLHENSLHQEESQKENMP 469
             A +E Q  D  +G  G           E S    G+S      H ++  QE S      
Sbjct: 1804 SASQEGQ--DTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSH---HSHTTSQERSDVSRGQ 1858

Query: 470  CGETAEFKQ----KQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVS 525
             G  +  +Q    KQS +  +    ++ ++ + A+  R     H+     Q        +
Sbjct: 1859 SGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSR-----HSQVGQGQSSGPRTSRN 1913

Query: 526  QKEAKHKITSADGHIESS 543
            Q  +  + + + GH E S
Sbjct: 1914 QGSSVSQDSDSQGHSEDS 1931


>gi|116805342 human immunodeficiency virus type I enhancer binding
            protein 1 [Homo sapiens]
          Length = 2718

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 59/273 (21%), Positives = 110/273 (40%), Gaps = 39/273 (14%)

Query: 141  VPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGIRPAR--V 198
            V D +  +S  SS ++ PV  L   +   +      P    T+ +   +  G +P +  V
Sbjct: 1488 VKDLQAETSNSSSTNVFPVQQLCDINLLNQIHAP--PSHQSTQLSLQVSTQGSKPDKNSV 1545

Query: 199  VSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQ------- 251
            +S +S+ E+ F  K+ +++C+  TSG    S  +   PN ++ DP   D  V        
Sbjct: 1546 LSGSSKSEDCFAPKY-QLHCQVFTSGPSCSSNPVHSLPNQVISDPVGTDHCVTSATLPTK 1604

Query: 252  --ENGCEEYGIMCP--------MEEVMSAAMYKEILDSKIK-------ESLP--IDIDQL 292
              ++    + ++ P        +++V S+ M    L S +         SLP  +    L
Sbjct: 1605 LIDSMSNSHPLLPPELRPLGSQVQKVPSSFMLPIRLQSSVPAYCFATLTSLPQILVTQDL 1664

Query: 293  SGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTE-------SELS 345
              +  C +       +EE +S +        +  P   +E L E+VF+E       SE  
Sbjct: 1665 PNQPICQTNHSVVPISEEQNS-VPTLQKGHQNALPNPEKEFLCENVFSEMSQNSSLSESL 1723

Query: 346  PIREELVSSDELRQDKSSGASSESVQTVNQAEV 378
            PI +++       Q +SS +S   +   N  ++
Sbjct: 1724 PITQKISVGRLSPQQESSASSKRMLSPANSLDI 1756


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 49/237 (20%), Positives = 94/237 (39%), Gaps = 32/237 (13%)

Query: 362 SSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAI 421
           SS AS E  +  NQ E   +  +             +E    EV     ++  ++ E   
Sbjct: 118 SSSASREPYK--NQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVN 175

Query: 422 KEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQS 481
            E+  +D+  G SG  ++    +GN         N+ ++EE  +E++   E  E   ++ 
Sbjct: 176 SEEYGSDHETGSSGSSDE----QGN---------NTENEEEGVEEDVEEDEEVEEDAEED 222

Query: 482 VNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEA----KHKITSAD 537
               + G+E+ ++ + E EE  +  + +   +  Q+ E     ++ EA       ++  D
Sbjct: 223 EEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282

Query: 538 GHIESSALL-----KEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHE 589
           G + S +       K+K+R R      +         F    S+  + YA  +KKHE
Sbjct: 283 GSVRSGSGTDGSDEKKKERKRARGISPI--------VFDRSGSSASESYAGSEKKHE 331


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 45/241 (18%), Positives = 102/241 (42%), Gaps = 30/241 (12%)

Query: 321 DSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVES 380
           D+   A +S++    +    + +   +++  V  D+ ++D      S   ++ +  +   
Sbjct: 287 DTKKNAKKSSDAESEDSKDAKKDSKKVKKN-VKKDDKKKDVKKDTESTDAESGDSKDERK 345

Query: 381 LTVKSESTGTPGHLRSDT----EHSTNEVGTLCH-KTDLNNLEMAIKEDQIADNFQGISG 435
            T K +        + DT    E +  E G     + D  NL+ A K D           
Sbjct: 346 DTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDD---------- 395

Query: 436 PKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDS 495
            K+D+  I  ++D      E+ L  +ESQK+     + ++   K+SV   ++  + + + 
Sbjct: 396 KKKDAKKITFSTDS-----ESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEP 450

Query: 496 QTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRHRLH 555
           + ++++ +K        + K ++++ +   +K+AK    S +  +ES   LK+ ++H   
Sbjct: 451 KGDSKKGKK-------DEKKGKKDSKKDDKKKDAKKNAESTE--MESDLELKKDKKHSKE 501

Query: 556 K 556
           K
Sbjct: 502 K 502


>gi|62244004 modulator of estrogen induced transcription isoform b
           [Homo sapiens]
          Length = 1016

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 52/283 (18%), Positives = 116/283 (40%), Gaps = 50/283 (17%)

Query: 302 KMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSE-DVFTESELSPIREELVSSDELRQD 360
           +++G  + E D+ I+D   ++     +   + L + + F E+E   +  + + S E  + 
Sbjct: 91  ELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKR 150

Query: 361 KSSGASSESVQTVNQAEVESLTVKSES-------TGTPGHLRSD-----------TEHST 402
                 +E ++ + + ++ES  ++++        T   G    +           T H  
Sbjct: 151 AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKEGSLAEADHTAHEE 210

Query: 403 NEVGTLCHKTDLNNLEMAIK-EDQIADNFQG----------------ISGPKEDSTSIKG 445
            E  T   + + +N+ + I+ ED I  +F G                 S PK+   +I  
Sbjct: 211 MEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQ 270

Query: 446 NSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQ-----DSQTEAE 500
           + +++S  +E + + ++ +KE+   G+  E + ++S  K + G ++        S T A 
Sbjct: 271 SPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGAS 330

Query: 501 ELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESS 543
              K         +K+ +++  + S K+ K   +S  G   SS
Sbjct: 331 GQAK-------SSSKESKDS--KTSSKDDKGSTSSTSGSSGSS 364



 Score = 37.4 bits (85), Expect = 0.059
 Identities = 88/489 (17%), Positives = 185/489 (37%), Gaps = 73/489 (14%)

Query: 74  DTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAV 133
           D+   K  D +D    S +K     E     +D      +K D    E  + +K      
Sbjct: 255 DSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESG- 313

Query: 134 VTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNP--DVHPTEATPSSTFT 191
                    D E   +++  PS +  S  + +SS+   D  T+   D   T +T  S+ +
Sbjct: 314 ---------DKEK-DTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGS 363

Query: 192 GIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQ 251
             +   V   +S  + A        + K +    G V    +VT               +
Sbjct: 364 STKNIWVSGLSSNTKAA--------DLKNLFGKYGKVLSAKVVTN-------------AR 402

Query: 252 ENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEI 311
             G + YGI+        +     +  +++   L I ++++ G      K+M   N E+ 
Sbjct: 403 SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQL-ISVEKVKGDP--SKKEMKKENDEKS 459

Query: 312 DSRIRDAGNDSASTAPRS--TEESLSEDVFTESELSPIRE-----ELVSSDELRQDKSSG 364
            SR   +  D  +T+ RS  T+ S+ ++    SE S  +E     ++   DE   + +SG
Sbjct: 460 SSR---SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASG 516

Query: 365 ASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKED 424
            +SES++       +S   K  S+ +PGH+             +  +T  ++   + +  
Sbjct: 517 QTSESIK-------KSEEKKRISSKSPGHM------------VILDQTKGDHCRPSRR-- 555

Query: 425 QIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNK 484
                ++ I G  ++      +  +D       +   E  KE         F++ +   +
Sbjct: 556 ---GRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAME 612

Query: 485 GKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSA 544
            ++ +E  +  + E E +R + +    ++ +++RE ++   QK  + ++      +E   
Sbjct: 613 LRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERE--RLERER 670

Query: 545 LLKEKQRHR 553
           +  E++R +
Sbjct: 671 IRIEQERRK 679



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 31/150 (20%), Positives = 66/150 (44%), Gaps = 5/150 (3%)

Query: 410 HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMP 469
           H+T+L+   +++++ +   + + +    ++ +S + + D+ +    +S  Q   +KE   
Sbjct: 428 HRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKR 487

Query: 470 CGETAEFKQKQSVNK--GKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQK 527
             E +E K+ +   K  GK  K  N  S   +E ++K       + + +   ++  + Q 
Sbjct: 488 SSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKK--SEEKKRISSKSPGHMVILDQT 545

Query: 528 EAKHKITSADGHIES-SALLKEKQRHRLHK 556
           +  H   S  G  E      KEK+R  L K
Sbjct: 546 KGDHCRPSRRGRYEKIHGRSKEKERASLDK 575


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 42/257 (16%), Positives = 85/257 (33%), Gaps = 4/257 (1%)

Query: 288  DIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPI 347
            D D  +  D  +S   + S+     S   D+ + S S +   ++ S S D    S+ S  
Sbjct: 817  DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876

Query: 348  REELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGT 407
             +   SSD      SS +S  S    N ++ +S    + S  +     SD+  S+N    
Sbjct: 877  SDSSDSSDSNESSNSSDSSDSS----NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932

Query: 408  LCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKEN 467
                   N+ + +   D    +    S    +S+    ++  DS    NS    +S   +
Sbjct: 933  SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992

Query: 468  MPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQK 527
                 +       S +        N    + + +      +     +    ++       
Sbjct: 993  DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052

Query: 528  EAKHKITSADGHIESSA 544
            ++ +   S+D    S +
Sbjct: 1053 DSSNSSDSSDSSDSSDS 1069



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 40/202 (19%), Positives = 77/202 (38%), Gaps = 8/202 (3%)

Query: 300 SKKMTGSNTEEIDSRIRDAGNDSA-STAPRSTEESLSEDVFTESELSPIREELVSSDELR 358
           S   + S+  E DS   D+ +DS+ S +  S++ S S D    S  S   +   SSD   
Sbjct: 620 SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD--- 676

Query: 359 QDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLE 418
               S +SS+S  + + ++    +  SES+ +     SD+  S++   +    +D +N  
Sbjct: 677 ----SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732

Query: 419 MAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQ 478
            +      +D+           +S   +S   S   ++S   + S   N      +    
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792

Query: 479 KQSVNKGKQGKEQNQDSQTEAE 500
             S +        + DS   ++
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSD 814



 Score = 38.1 bits (87), Expect = 0.035
 Identities = 41/247 (16%), Positives = 92/247 (37%), Gaps = 6/247 (2%)

Query: 300 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSE--DVFTESELSPIREELVSSDEL 357
           S     S++ + DS   ++ +DS S+   S++ S S+  D    S+ S   +   SSD  
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS- 616

Query: 358 RQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNL 417
             D S   S  S    + ++ +S +  S+S  +     SD+  S+N   +       ++ 
Sbjct: 617 -SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS 675

Query: 418 EMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFK 477
           + +   D  + N    S   + S S + +   DS   ++S   + S   +     +    
Sbjct: 676 DSSSSSD--SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD 733

Query: 478 QKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSAD 537
              S N        +  + +++ +      +     +    ++    +  ++     S+D
Sbjct: 734 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793

Query: 538 GHIESSA 544
               S++
Sbjct: 794 SSDSSNS 800



 Score = 38.1 bits (87), Expect = 0.035
 Identities = 34/198 (17%), Positives = 73/198 (36%), Gaps = 4/198 (2%)

Query: 306 SNTEEIDSRIRDAGNDS----ASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDK 361
           S ++  DS   D+ ++S    +S +  S++ S S D    S  S       SSD      
Sbjct: 638 SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN 697

Query: 362 SSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAI 421
           SS +S  S  + + +   S +  S S+ +     SD+  S+N   +       N+ + + 
Sbjct: 698 SSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD 757

Query: 422 KEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQS 481
             D    +    S    DS+    +SD +   + +      +  ++    ++++      
Sbjct: 758 SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817

Query: 482 VNKGKQGKEQNQDSQTEA 499
            +        N    +++
Sbjct: 818 SDSSNSSDSSNSSDSSDS 835



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 44/222 (19%), Positives = 76/222 (34%), Gaps = 5/222 (2%)

Query: 279 SKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDV 338
           S   +S   D    S  D   S   + S+     S   D+ + S S +  S  ES S D 
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDS 636

Query: 339 FTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDT 398
            ++S+ S       SSD      SS +S+ S  + +    +S    S S  +     SD+
Sbjct: 637 DSKSDSSDSN----SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692

Query: 399 EHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSL 458
             S+N        +D ++ + +   D    N           +S   NS   S   ++S 
Sbjct: 693 SDSSNS-SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751

Query: 459 HQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAE 500
             + S   +      +      S +        + DS   ++
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 36/215 (16%), Positives = 84/215 (39%), Gaps = 7/215 (3%)

Query: 290 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDS-ASTAPRSTEESLSEDVFTESELSPIR 348
           D  +  D   S   + S+     S   D+ + S +S +  S+  S S D    S+ S   
Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807

Query: 349 EELVSSDELRQDKSSGA----SSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTN- 403
           +   SSD    D S+ +    SS+S  + N ++    +  S+ + +    RSD+ +S++ 
Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867

Query: 404 -EVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEE 462
            +     + +D ++   + +    +D+    +    DS+    +SD     + +   +  
Sbjct: 868 SDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 927

Query: 463 SQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQT 497
           +  +N    +++        +      + +  S +
Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDS 962



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 38/215 (17%), Positives = 72/215 (33%), Gaps = 2/215 (0%)

Query: 290  DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 349
            D     D   S   + S+     S   D+ N S S+   S++ S S D    S+ S   +
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSD--SSDSSDSSDSSDSSDSSDSSD 1119

Query: 350  ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 409
               SSD      SS +S  S  + +    ES      S  +     SD+  S++   +  
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1179

Query: 410  HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMP 469
                 ++ + +   D    +    S    DS+    +SD       +         ++  
Sbjct: 1180 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSD 1239

Query: 470  CGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRK 504
              ++++       +      +   DS  E++   K
Sbjct: 1240 SSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 43/213 (20%), Positives = 80/213 (37%), Gaps = 4/213 (1%)

Query: 290  DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 349
            D     D   S   + S+     S   D+ + S S+   S++ S S D    S+ S   +
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSNSSDSSDSSDSSDSSD 1137

Query: 350  ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 409
               SSD     +SS +S  S  + +    +S      S  +     SD+  S++   +  
Sbjct: 1138 SSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1197

Query: 410  HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSD-QDSFLHENSLHQEESQKENM 468
                 ++ + +   D    +    S    DS+    +SD  DS    +S +  +S   + 
Sbjct: 1198 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD 1257

Query: 469  PCGETAEFK-QKQSVNKGKQGKEQNQDSQTEAE 500
                T++   +  S +K   G     DS +++E
Sbjct: 1258 SSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSE 1290



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 38/212 (17%), Positives = 78/212 (36%), Gaps = 4/212 (1%)

Query: 288 DIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPI 347
           D D  S  D  +S      N    D+   D+G   + ++   + +S +    ++S  S  
Sbjct: 512 DDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571

Query: 348 REELVSSDELRQDKSSGAS--SESVQTVNQAEVESLTVKSESTGT--PGHLRSDTEHSTN 403
            +   SSD    D  S  S  S+S  + N ++    +  S+S+ +      +SD+  S +
Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631

Query: 404 EVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEES 463
           +      K+D ++   +   D    +    S    DS+    +SD  S    ++      
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691

Query: 464 QKENMPCGETAEFKQKQSVNKGKQGKEQNQDS 495
             ++    E+++       +        N +S
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS 723



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 37/197 (18%), Positives = 72/197 (36%), Gaps = 2/197 (1%)

Query: 300 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQ 359
           S     SN+ E       + +DS+ ++  S   S   D    S+ S       SSD    
Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS 749

Query: 360 DKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEM 419
             SS  SS+S  + N ++    +  S+S+ +     S+   ++++     + +D +N   
Sbjct: 750 SNSSD-SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808

Query: 420 AIKEDQIADNFQGISGPKEDST-SIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQ 478
           +      +D+    S    +S+ S   ++  DS    +S    +S   N      +    
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868

Query: 479 KQSVNKGKQGKEQNQDS 495
             S +        + DS
Sbjct: 869 DSSDSSNSSDSSDSSDS 885



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 33/202 (16%), Positives = 74/202 (36%), Gaps = 6/202 (2%)

Query: 300  SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQ 359
            S     SN+ +       + N ++S +  S++ S S D    S+ S   +   SSD    
Sbjct: 912  SDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS--S 969

Query: 360  DKSSGASSESVQTVNQAEVESLTVKSESTGTPGHL----RSDTEHSTNEVGTLCHKTDLN 415
            D +S  SS+S  + + ++    +  S+S+ +         SD+  S+N   +       N
Sbjct: 970  DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029

Query: 416  NLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAE 475
            + + +   D    +    S    DS++   +SD       +         ++    ++++
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089

Query: 476  FKQKQSVNKGKQGKEQNQDSQT 497
                   +      + +  S +
Sbjct: 1090 SSNSSDSSDSSDSSDSSDSSDS 1111



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 45/222 (20%), Positives = 76/222 (34%), Gaps = 14/222 (6%)

Query: 275  EILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESL 334
            E  DS    +     D     D   S   + S+     S   D+ + S S+   S++ S 
Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSDSSN 1140

Query: 335  SEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHL 394
            S D    SE S   +   SSD      SS +S  S  + +    +S      S  +    
Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1200

Query: 395  RSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLH 454
             SD+  S++   +       ++ + +   D    +    S    DS++   +SD      
Sbjct: 1201 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSD 1260

Query: 455  ENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQ 496
              S   +ES              Q +S N    G + + DS+
Sbjct: 1261 STSDSNDESD------------SQSKSGNGNNNGSDSDSDSE 1290



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 39/222 (17%), Positives = 78/222 (35%), Gaps = 14/222 (6%)

Query: 278  DSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSED 337
            DS  +       D     D  +S   + S+     S   D+ + S S+   S++ S S D
Sbjct: 854  DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913

Query: 338  VFTESELSPIREELVSSDELRQDKSSGAS--SESVQTVNQAEVESLTVKSESTGTPGHLR 395
                S  S   E   SSD      SS +S  S+S  + N ++  + +  S S+ +     
Sbjct: 914  SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973

Query: 396  SDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHE 455
            SD+  S+N            + + +   D    +    S    DS+    +SD  +    
Sbjct: 974  SDSSDSSN------------SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021

Query: 456  NSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQT 497
            ++     +  ++    ++++       +        +  S +
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 34/209 (16%), Positives = 73/209 (34%), Gaps = 1/209 (0%)

Query: 290  DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDS-ASTAPRSTEESLSEDVFTESELSPIR 348
            D  +  D   S   + S+     S   D+ + S +S +  S++ S S D    S+ S   
Sbjct: 978  DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037

Query: 349  EELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTL 408
            +   SSD      SS +S+ S  + +    +S      S  +     SD+  S+N   + 
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097

Query: 409  CHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENM 468
                  ++ + +   D    +    S    DS+    +SD  +    +   +     ++ 
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS 1157

Query: 469  PCGETAEFKQKQSVNKGKQGKEQNQDSQT 497
               ++++       +        +  S +
Sbjct: 1158 DSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1186



 Score = 34.3 bits (77), Expect = 0.50
 Identities = 45/224 (20%), Positives = 78/224 (34%), Gaps = 12/224 (5%)

Query: 278 DSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSED 337
           DSK   S     D     D   S     SN+ +       + + S+S +  S++ S S D
Sbjct: 637 DSKSDSSDSNSSDSSDNSD--SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694

Query: 338 VFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSD 397
               SE S   +   SSD    D S  ++S      N ++ +S      S  +     SD
Sbjct: 695 SSNSSESSDSSD---SSDSDSSDSSDSSNS------NSSDSDSSNSSDSSDSSNSSDSSD 745

Query: 398 TEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSD-QDSFLHEN 456
           +  S+N   +       N+ + +   D    +    S    DS++   +SD  +S    N
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805

Query: 457 SLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAE 500
           S    +S   +      +      S +        + DS   ++
Sbjct: 806 SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849



 Score = 34.3 bits (77), Expect = 0.50
 Identities = 34/198 (17%), Positives = 74/198 (37%), Gaps = 3/198 (1%)

Query: 300  SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQ 359
            S   + S+     S   D+ N S S+   S++ S S +    S+ S   +   SSD    
Sbjct: 944  SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003

Query: 360  DKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEM 419
              SS  SS+S  + N ++  + +  S S+ +     SD+  S++   +       N+ + 
Sbjct: 1004 SDSSD-SSDSSDSSNSSDSSNSSDSSNSSDSSDS--SDSSDSSDSSDSSDSSDSSNSSDS 1060

Query: 420  AIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQK 479
            +   D    +    S    DS+    +SD  +    +         ++    ++++    
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120

Query: 480  QSVNKGKQGKEQNQDSQT 497
             + +      + +  S +
Sbjct: 1121 SNSSDSSDSSDSSDSSDS 1138



 Score = 34.3 bits (77), Expect = 0.50
 Identities = 38/211 (18%), Positives = 78/211 (36%), Gaps = 7/211 (3%)

Query: 288  DIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDS-ASTAPRSTEESLSEDVFTESELSP 346
            D +     D  +S   + S+     S   D+ N S +S +  S++ S S D    S+ S 
Sbjct: 970  DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029

Query: 347  IREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVG 406
              +   SSD      SS  SS+S  + N ++    +  S+S+ +     SD+  S++   
Sbjct: 1030 SSDSSDSSDSSDSSDSSD-SSDSSDSSNSSDSSDSSDSSDSSDS-----SDSSDSSDSSE 1083

Query: 407  TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKE 466
            +       N+ + +   D    +    S    DS+    +SD       +      +  +
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143

Query: 467  NMPCGETAEFKQKQSVNKGKQGKEQNQDSQT 497
            +    E+++       +      + +  S +
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDS 1174



 Score = 33.9 bits (76), Expect = 0.65
 Identities = 32/208 (15%), Positives = 70/208 (33%)

Query: 290  DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 349
            D     D  +S   + S+     S   D+ +  +S +  S++ S S D    S+ S    
Sbjct: 943  DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002

Query: 350  ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 409
               SSD      SS +S  S  + +    +S      S  +     SD+  S+N   +  
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062

Query: 410  HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMP 469
                 ++ + +   D    +    S    +S+    +SD       +         ++  
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122

Query: 470  CGETAEFKQKQSVNKGKQGKEQNQDSQT 497
              ++++       +      + +  S++
Sbjct: 1123 SSDSSDSSDSSDSSDSSNSSDSSDSSES 1150



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 35/208 (16%), Positives = 69/208 (33%), Gaps = 2/208 (0%)

Query: 290  DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 349
            D  +  D   S   + S+     S   D+ N S S+   S++ S S D    S+ S   E
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD--SSDSSDSSDSSDSSDSSDSSE 1083

Query: 350  ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 409
               SSD      SS +S  S  + +    +S      S  +     SD+  S++   +  
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143

Query: 410  HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMP 469
                  + + +   D    +    S    DS+    +SD       +         ++  
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203

Query: 470  CGETAEFKQKQSVNKGKQGKEQNQDSQT 497
              ++++       +      + +  S +
Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 44/256 (17%), Positives = 87/256 (33%), Gaps = 14/256 (5%)

Query: 290 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESEL-SPIR 348
           D     D   S   + S+     S   D+ N S S+    + +S S D    S   S   
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726

Query: 349 EELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTL 408
           +   SSD      SS +S  S  + +    +S    + S  +     SD+  S+N     
Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN----- 781

Query: 409 CHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENM 468
              +D N  + +   D    +    S    DS+    +SD DS    +S +  +S   + 
Sbjct: 782 --SSDSN--DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS- 836

Query: 469 PCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKE 528
               +++       + G      N+   + + +      +     +    ++ +  +  +
Sbjct: 837 ---NSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893

Query: 529 AKHKITSADGHIESSA 544
           +     S+D     S+
Sbjct: 894 SSDSSNSSDSDSSDSS 909



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 35/202 (17%), Positives = 72/202 (35%), Gaps = 4/202 (1%)

Query: 300  SKKMTGSNTEEIDSRIRDAGNDSA--STAPRSTEESLSEDVFTESELSPIREELVSSDEL 357
            S     SN+ + DS      +DS+  S +  S+E S S D    S+ S   +   SSD  
Sbjct: 892  SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951

Query: 358  RQDKSSGAS--SESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLN 415
                SS +S  S S  + +    +S    + S  +     SD+  S++   +       +
Sbjct: 952  NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011

Query: 416  NLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAE 475
            + + +   D    +    S    DS+    +SD       +         ++    ++++
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071

Query: 476  FKQKQSVNKGKQGKEQNQDSQT 497
                   +   +  + +  S +
Sbjct: 1072 SSDSSDSSDSSESSDSSDSSNS 1093



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 35/208 (16%), Positives = 69/208 (33%), Gaps = 2/208 (0%)

Query: 290  DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 349
            D  +  D   S   + S+     S   D+ N S S+   S++ S S D    S+ S    
Sbjct: 999  DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD--SSDSSDSSDSSDSSDSSDSSN 1056

Query: 350  ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 409
               SSD      SS +S  S  + +    +S    + S  +     SD+  S++   +  
Sbjct: 1057 SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1116

Query: 410  HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMP 469
                 N+ + +   D    +    S    DS+    +SD       +         ++  
Sbjct: 1117 SSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSD 1176

Query: 470  CGETAEFKQKQSVNKGKQGKEQNQDSQT 497
               +++       +      + +  S +
Sbjct: 1177 SSNSSDSSDSSDSSDSSDSSDSSDSSDS 1204



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 41/210 (19%), Positives = 76/210 (36%), Gaps = 16/210 (7%)

Query: 290 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 349
           D  +  D   S   + S+     S   ++ + S S+    ++ S S D    S+ S    
Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837

Query: 350 ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 409
              SSD    D S G+ S+S    N+++  + +  S+S+ +     S     +NE     
Sbjct: 838 SSDSSDS--SDSSDGSDSDSS---NRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892

Query: 410 HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSD--QDSFLHENSLHQEESQKEN 467
             +D +N          +D+    S    DS+    +SD  + S   +NS   + S   +
Sbjct: 893 DSSDSSNS---------SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD 943

Query: 468 MPCGETAEFKQKQSVNKGKQGKEQNQDSQT 497
                 +      S +        + DS +
Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 35/210 (16%), Positives = 74/210 (35%), Gaps = 6/210 (2%)

Query: 290  DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 349
            D     D   S   + S+     S   D+ N S S+   S++ S S D    S+ S   +
Sbjct: 987  DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS--NSSDSSNSSDSSDSSDSSDSSD 1044

Query: 350  ELVSSDELRQDKSSGAS--SESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGT 407
               SSD      SS +S  S+S  + + ++    +  SES+ +     S     +++   
Sbjct: 1045 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD 1104

Query: 408  LCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKEN 467
                +D ++   +      +D+    S    DS+    +SD       +         ++
Sbjct: 1105 SSDSSDSSDSSDSSDSSNSSDSSD--SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDS 1162

Query: 468  MPCGETAEFKQKQSVNKGKQGKEQNQDSQT 497
                ++++       +      + +  S +
Sbjct: 1163 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 30/198 (15%), Positives = 66/198 (33%)

Query: 300  SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQ 359
            S     SN+ +       + +  +S +  S++ S S D    S  S   +   SSD    
Sbjct: 1049 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDS 1108

Query: 360  DKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEM 419
              SS +S  S  + +    +S      S  +     SD+  S++   +       ++ + 
Sbjct: 1109 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDS 1168

Query: 420  AIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQK 479
            +   D    +    S    DS+    +SD       +         ++    ++++    
Sbjct: 1169 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228

Query: 480  QSVNKGKQGKEQNQDSQT 497
               N+     + +  S +
Sbjct: 1229 SDSNESSDSSDSSDSSDS 1246



 Score = 30.4 bits (67), Expect = 7.2
 Identities = 41/214 (19%), Positives = 79/214 (36%), Gaps = 9/214 (4%)

Query: 290  DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDS-ASTAPRSTEESLSEDVFTESELSPIR 348
            D     D   S   + S+     S   D+ + S +S +  S++ S S D    S+ S   
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064

Query: 349  EELVSSDELRQDKSSGAS--SESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVG 406
            +   SSD      SS +S  S+S  + N ++    +  S+S+ +     SD+  S++   
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDS-----SDSSDSSDSSD 1119

Query: 407  TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKE 466
            +       ++ + +   D    +    S    DS+    +SD  S   ++S   + S   
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD-SSDSSDSSDSSDSSDSS 1178

Query: 467  NMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAE 500
            N      +      S +        + DS   ++
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212



 Score = 30.0 bits (66), Expect = 9.4
 Identities = 30/208 (14%), Positives = 70/208 (33%)

Query: 290  DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 349
            D  +  D   S     S++         + +  +S +  S+  S S D    S+ S   +
Sbjct: 961  DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020

Query: 350  ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 409
               SSD      SS +S  S  + +    +S    + S  +     SD+  S++   +  
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080

Query: 410  HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMP 469
                 ++ + +   D    +    S    DS+    +SD  +    +         ++  
Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140

Query: 470  CGETAEFKQKQSVNKGKQGKEQNQDSQT 497
              ++++  +    +      + +  S +
Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDS 1168



 Score = 30.0 bits (66), Expect = 9.4
 Identities = 32/209 (15%), Positives = 73/209 (34%), Gaps = 1/209 (0%)

Query: 290  DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDS-ASTAPRSTEESLSEDVFTESELSPIR 348
            D  +  D  +S   + S+     S   D+ + S +S +  S+  S S D    S+ S   
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073

Query: 349  EELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTL 408
            +   SSD      SS +S+ S  + +    +S      S  +     S++  S++   + 
Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133

Query: 409  CHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENM 468
                  N+ + +   +    +    S    DS+    +SD     + +         ++ 
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1193

Query: 469  PCGETAEFKQKQSVNKGKQGKEQNQDSQT 497
               ++++       +      + +  S +
Sbjct: 1194 DSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1222


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 78/395 (19%), Positives = 143/395 (36%), Gaps = 80/395 (20%)

Query: 265 EEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSAS 324
           +E  +A    E  ++K  E     +      D    K+ T  +  + +    D+G +   
Sbjct: 213 QEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLE 272

Query: 325 TAPRSTEES---------------------LSEDVFTES-----------ELSPIREELV 352
           TAP+S E S                     L++DV  ES           E  P   E  
Sbjct: 273 TAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKG 332

Query: 353 SSDELRQDKSS-----GASSESVQTV------NQAEVESLTVKSESTGTPGH-------- 393
              + +++K+         SE  Q V       + EVESL + SE               
Sbjct: 333 ERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKED 392

Query: 394 ---LRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQ---GISGPKE--------- 438
              + SD +  T+   +  H +DL++ E   +E+ +  +      I+   E         
Sbjct: 393 FSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTK 452

Query: 439 ----DSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQD 494
               DS+  K  S + +++H+  L+ +     +    E    +++QS+ K K+ +   + 
Sbjct: 453 TQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSD---DELTVEQRRQSIAKEKEERLLRRQ 509

Query: 495 SQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKE--KQRH 552
              E  E ++  K    + +K + +    V  +E+  K          +A +KE  K+R 
Sbjct: 510 INREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLE-----PKAARIKEVLKERK 564

Query: 553 RLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKK 587
            L K + L   +      V + S   QQY +  K+
Sbjct: 565 VLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKE 599



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 55/259 (21%), Positives = 99/259 (38%), Gaps = 44/259 (16%)

Query: 297  FCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDV--------FTESELSPIR 348
            +  S+     N + +DSRI  A      T P  T+E  S D+         T S  S + 
Sbjct: 2777 YLSSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVM 2836

Query: 349  EELVSSDELRQDKSSGASSE--SVQTVNQAEVESLTVKSESTGTPGHLRSDT-------- 398
            EE    DE    +++G   E     T+   E +   +     G P     +T        
Sbjct: 2837 EE---KDEYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDS 2893

Query: 399  ---------EHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSI--KGNS 447
                     E S +       +TD +N E A  +++   N     G ++  TS+  +G  
Sbjct: 2894 KTDTGIVTVEQSPSSSKLKVMQTDESNKETANLQERSISN---DDGEEKIVTSVRRRGRK 2950

Query: 448  DQDSF-LHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQD------SQTEAE 500
             + S  + +++   E  +K      +  E K++Q  ++ ++ +E+++       S T +E
Sbjct: 2951 PKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSE 3010

Query: 501  ELRKLWKTHTMQQTKQQRE 519
              R   KT      K++RE
Sbjct: 3011 AQRS--KTQLSPSIKRKRE 3027



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 33/150 (22%), Positives = 66/150 (44%), Gaps = 20/150 (13%)

Query: 384 KSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGP-KEDSTS 442
           K++S+ T G  RS  +   +   +L  K     ++  +KE ++ +    +S   K+DS +
Sbjct: 525 KTKSSKTKGQGRSSVDLEESSTKSLEPKAA--RIKEVLKERKVLEKKVALSKKRKKDSRN 582

Query: 443 IKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEEL 502
           ++ NS +           EE  KE +   +T+E  +K+ ++  K+ K  +  S+      
Sbjct: 583 VEENSKKKQ-------QYEEDSKETL---KTSEHCEKEKISSSKELKHVHAKSEPSKPAR 632

Query: 503 RKLWKTHTMQQTKQQRENIQQVSQKEAKHK 532
           R     H + + K +       S+ E +HK
Sbjct: 633 RLSESLHVVDENKNE-------SKLEREHK 655



 Score = 30.0 bits (66), Expect = 9.4
 Identities = 46/243 (18%), Positives = 94/243 (38%), Gaps = 25/243 (10%)

Query: 302  KMTGSNTEEIDSRIRDAGNDSASTAP----RSTEESLSEDV---------FTESELSPIR 348
            K  G   + +++ +++     A+T      ++TEE+ SE           F E+ + P+ 
Sbjct: 915  KTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVL 974

Query: 349  EELVSSDELRQ-DKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGT 407
            E   SS    Q D S  A     +   +++ +S + + E   + GH     +HS+ ++  
Sbjct: 975  ETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDI-- 1032

Query: 408  LCHKTDLNNLE--MAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQK 465
               K D N  +     + D   +  +G S   E   S +   ++       SL QE ++ 
Sbjct: 1033 --KKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKLSRRLCENR-----RGSLSQEMAKG 1085

Query: 466  ENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVS 525
            E      T       S+ + K+  +     + E  E+        + +  + ++N    S
Sbjct: 1086 EEKLAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEIDSEPGVENVFEVSKTQDNRNNNS 1145

Query: 526  QKE 528
            Q++
Sbjct: 1146 QQD 1148


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 51/242 (21%), Positives = 98/242 (40%), Gaps = 32/242 (13%)

Query: 410 HKTDLNNLEMAIKEDQIA-----DNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQ 464
           H+  L  L+ A++  ++A     D    +   KE  + ++     ++ L E      + Q
Sbjct: 561 HRDSLVTLKRALEAKELARQHLRDQLDEVE--KETRSKLQEIDIFNNQLKELREIHNKQQ 618

Query: 465 KENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQR-ENIQQ 523
            +     E    KQK+   K  + ++Q +++Q  A+E  K W  H  Q+ + QR   + +
Sbjct: 619 LQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHE 678

Query: 524 VSQKEAKHKITSADGHIESSALLKEKQRHRLHKFLCLRVGKP-MRKTFVSQASATMQQYA 582
             + + +  +   DG  +     ++K     H+       KP ++  + +     +   A
Sbjct: 679 EEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQH--QEPAKPAVQAPWSTAEKGPLTISA 736

Query: 583 QRDKKHEYWFAV-PQERTDHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKK---IEESET 638
           Q + K  Y+ A+ P E   H                  E T +PG IV+ K   ++ES+T
Sbjct: 737 QENVKVVYYRALYPFESRSH-----------------DEITIQPGDIVMVKGEWVDESQT 779

Query: 639 IE 640
            E
Sbjct: 780 GE 781


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 51/242 (21%), Positives = 98/242 (40%), Gaps = 32/242 (13%)

Query: 410 HKTDLNNLEMAIKEDQIA-----DNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQ 464
           H+  L  L+ A++  ++A     D    +   KE  + ++     ++ L E      + Q
Sbjct: 561 HRDSLVTLKRALEAKELARQHLRDQLDEVE--KETRSKLQEIDIFNNQLKELREIHNKQQ 618

Query: 465 KENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQR-ENIQQ 523
            +     E    KQK+   K  + ++Q +++Q  A+E  K W  H  Q+ + QR   + +
Sbjct: 619 LQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHE 678

Query: 524 VSQKEAKHKITSADGHIESSALLKEKQRHRLHKFLCLRVGKP-MRKTFVSQASATMQQYA 582
             + + +  +   DG  +     ++K     H+       KP ++  + +     +   A
Sbjct: 679 EEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQH--QEPAKPAVQAPWSTAEKGPLTISA 736

Query: 583 QRDKKHEYWFAV-PQERTDHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKK---IEESET 638
           Q + K  Y+ A+ P E   H                  E T +PG IV+ K   ++ES+T
Sbjct: 737 QENVKVVYYRALYPFESRSH-----------------DEITIQPGDIVMVKGEWVDESQT 779

Query: 639 IE 640
            E
Sbjct: 780 GE 781


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 50/199 (25%), Positives = 85/199 (42%), Gaps = 24/199 (12%)

Query: 328  RSTEESLS--EDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKS 385
            RS EE+L    D   E+    I  +L   +EL+         E  +T+++       + S
Sbjct: 1692 RSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMH--LKEHQETIDKLR----GIVS 1745

Query: 386  ESTGTPGHLRSDTEHSTNEVGT--LCHKTDLNNLEMAIKEDQ-IADNFQGISGPKEDSTS 442
            E T    +++ D EHS + +    L  + +L    M +KE Q   D  +GI   K D  S
Sbjct: 1746 EKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLS 1805

Query: 443  IKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEEL 502
               N  +D    ENS  + + + + +   E      K+ VN       + Q   +E E+L
Sbjct: 1806 ---NMQKDL---ENSNAKLQEKIQELKANEHQLITLKKDVN-------ETQKKVSEMEQL 1852

Query: 503  RKLWKTHTMQQTKQQRENI 521
            +K  K  ++  +K + EN+
Sbjct: 1853 KKQIKDQSLTLSKLEIENL 1871



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 43/194 (22%), Positives = 75/194 (38%), Gaps = 44/194 (22%)

Query: 374 NQAEVESLTVKSESTGTPGH---LRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNF 430
           N+A  E + + SE    P     LR + +  + E+  +  + D    E+  KE ++    
Sbjct: 736 NEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLL 795

Query: 431 QGISGPKEDSTSIKGN--SDQDSFLHENSLHQEESQKENMPCGE---------------- 472
           + I   K+D  + + N  S    F +  +LH +  QK  M   E                
Sbjct: 796 EEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQ 855

Query: 473 ----------------TAEFKQK-----QSVNKGKQGKEQ--NQDSQTEAEELRKLWKTH 509
                           T E ++K     + +N+ +Q KEQ  N+DS  +  E  K   T 
Sbjct: 856 KFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITE 915

Query: 510 TMQQTKQQRENIQQ 523
            +QQT ++ + + Q
Sbjct: 916 KLQQTLEEVKTLTQ 929


>gi|117414154 sodium channel associated protein 2 isoform b [Homo
           sapiens]
          Length = 939

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 8/124 (6%)

Query: 487 QGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALL 546
           + K+Q +D       L K  +    Q+ +QQ   I+ + + E K      + ++  ++L 
Sbjct: 416 KAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLH 475

Query: 547 KEK-QRHRLHKFLCLRVGKPMR----KTFVSQA---SATMQQYAQRDKKHEYWFAVPQER 598
           +E+ Q  +LH+ L L+  +  +    + F + A    A  ++ A+ +KKHE      QE+
Sbjct: 476 REREQAQQLHQLLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEK 535

Query: 599 TDHL 602
            D L
Sbjct: 536 IDVL 539



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 47/208 (22%), Positives = 83/208 (39%), Gaps = 36/208 (17%)

Query: 334 LSEDVFTESELSPIR-EELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG 392
           +SE    ES +  +R E  V   EL Q  SS A +       +A++ESL+ ++E      
Sbjct: 656 ISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKL---EAQIESLSRENEC----- 707

Query: 393 HLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSF 452
            LR   E  ++ +   C   D     +   +D + +  + I   +E  T I+        
Sbjct: 708 -LRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIE-------- 758

Query: 453 LHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKT---- 508
                  QE+  +++    E  E  ++ +  K K  K+Q +  + E EE+RK + T    
Sbjct: 759 ----KCTQEQLDEKSSQLDEVLEKLERHNERKEKL-KQQLKGKEVELEEIRKAYSTLNRK 813

Query: 509 ---------HTMQQTKQQRENIQQVSQK 527
                    H   Q K+ +E  +   +K
Sbjct: 814 WHDKGELLCHLETQVKEVKEKFENKEKK 841


>gi|117414162 sodium channel associated protein 2 isoform a [Homo
           sapiens]
          Length = 1032

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 8/124 (6%)

Query: 487 QGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALL 546
           + K+Q +D       L K  +    Q+ +QQ   I+ + + E K      + ++  ++L 
Sbjct: 509 KAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLH 568

Query: 547 KEK-QRHRLHKFLCLRVGKPMR----KTFVSQA---SATMQQYAQRDKKHEYWFAVPQER 598
           +E+ Q  +LH+ L L+  +  +    + F + A    A  ++ A+ +KKHE      QE+
Sbjct: 569 REREQAQQLHQLLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEK 628

Query: 599 TDHL 602
            D L
Sbjct: 629 IDVL 632



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 47/208 (22%), Positives = 83/208 (39%), Gaps = 36/208 (17%)

Query: 334 LSEDVFTESELSPIR-EELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG 392
           +SE    ES +  +R E  V   EL Q  SS A +       +A++ESL+ ++E      
Sbjct: 749 ISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKL---EAQIESLSRENEC----- 800

Query: 393 HLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSF 452
            LR   E  ++ +   C   D     +   +D + +  + I   +E  T I+        
Sbjct: 801 -LRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIE-------- 851

Query: 453 LHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKT---- 508
                  QE+  +++    E  E  ++ +  K K  K+Q +  + E EE+RK + T    
Sbjct: 852 ----KCTQEQLDEKSSQLDEVLEKLERHNERKEKL-KQQLKGKEVELEEIRKAYSTLNRK 906

Query: 509 ---------HTMQQTKQQRENIQQVSQK 527
                    H   Q K+ +E  +   +K
Sbjct: 907 WHDKGELLCHLETQVKEVKEKFENKEKK 934


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 58/275 (21%), Positives = 109/275 (39%), Gaps = 34/275 (12%)

Query: 276 ILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEE------IDSRIRDA---GNDSASTA 326
           + DS+  E L ++       +  H +K + S +EE       DS   D    G+DS S  
Sbjct: 66  VTDSENDEPLNLNASDSESEEL-HRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEE 124

Query: 327 PR------STEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVES 380
            R      S  E L     ++SE   + +   S  E+ + + S AS    +   + ++  
Sbjct: 125 TRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISD 184

Query: 381 LTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDS 440
               SES   P H  SD+E   NE       +D  + E+   + Q++D+        E+ 
Sbjct: 185 ----SESEEPPRHQASDSE---NEEPPKPRMSDSESEELP--KPQVSDS------ESEEP 229

Query: 441 TSIKGNSDQDSFLHENSLHQEESQ---KENMPCGETAEFKQKQSVNKGKQGKEQNQDSQT 497
              + +  ++  L +  +   ES+   +      E  E  + +  +   +   +NQ S +
Sbjct: 230 PRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDS 289

Query: 498 EAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHK 532
           E EEL K   + +  +  Q+       ++  ++HK
Sbjct: 290 ENEELPKPRVSDSESEGPQKGPASDSETEDASRHK 324


>gi|195976782 Paf1/RNA polymerase II complex component [Homo
           sapiens]
          Length = 710

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 59/299 (19%), Positives = 122/299 (40%), Gaps = 43/299 (14%)

Query: 311 IDSRIRDAGNDS------ASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSG 364
           IDS   D+G+D        S A R   +S       E +  P+ +   SSD    D    
Sbjct: 51  IDSDTEDSGSDENLDQELLSLAKRKRSDS-------EEKEPPVSQPAASSDSETSDSDDE 103

Query: 365 ASSESVQTVNQAEVESL----TVKSESTGTPGHLRSD----TEHSTNEVGTLCHK----- 411
            +  S +   + +   +    T+K ++  T     SD     E S  E G +        
Sbjct: 104 WTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSS 163

Query: 412 TDLNNLEMAIKEDQIADNF-QGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPC 470
           +  ++ + + ++++  D + + + G +ED   ++  ++++    E  L     ++E +  
Sbjct: 164 SSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKE---REQELFNRIEKREVLK- 219

Query: 471 GETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAK 530
               E K+K    K K+ KE+ +  Q E +E +KL +    Q T   +E      + +  
Sbjct: 220 -RRFEIKKKLKTAKKKEKKEKKK-KQEEEQEKKKLTQIQESQVTSHNKER-----RSKRD 272

Query: 531 HKITSADGHIESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHE 589
            K+      +E     +EK+++R  + L  +  +P++    S+  +  ++  + DK  E
Sbjct: 273 EKLDKKSQAMEELKAEREKRKNRTAELLAKK--QPLK---TSEVYSDDEEEEEDDKSSE 326


>gi|119226220 membrane-spanning 4-domains, subfamily A, member 14
           isoform 2 [Homo sapiens]
          Length = 662

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 50/226 (22%), Positives = 96/226 (42%), Gaps = 23/226 (10%)

Query: 342 SELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHS 401
           SE+    +E  S +EL + KSS   S + QT     +   ++  ++ G     +S   HS
Sbjct: 445 SEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQ----KSSKRHS 500

Query: 402 TNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSF-LHENSLHQ 460
            ++           +L+  IK+            PK  S   +   +Q    L +     
Sbjct: 501 LDQQSKGWQSPKQKSLDQQIKD---------WLSPKRHSVDKQAQLNQTKEQLPDQQAED 551

Query: 461 EESQKENMPCGETAEFKQK-QSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRE 519
           ++++ E  P G++ + + K Q  +K +  K+Q QD QTE +  ++       +  K Q +
Sbjct: 552 QQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQE------KKSPKGQFQ 605

Query: 520 NIQQVSQKEAKHKITSADGHIESSALLKEKQRHRLHKFLCLRVGKP 565
           N+Q   Q+    K+       +S + +++ Q  + HK   L+ G+P
Sbjct: 606 NVQAEGQQAQVEKVPKLLCQ-DSESQIQQYQFWQFHKG-NLQAGQP 649


>gi|119226217 membrane-spanning 4-domains, subfamily A, member 14
           isoform 1 [Homo sapiens]
          Length = 679

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 50/226 (22%), Positives = 96/226 (42%), Gaps = 23/226 (10%)

Query: 342 SELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHS 401
           SE+    +E  S +EL + KSS   S + QT     +   ++  ++ G     +S   HS
Sbjct: 462 SEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQ----KSSKRHS 517

Query: 402 TNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSF-LHENSLHQ 460
            ++           +L+  IK+            PK  S   +   +Q    L +     
Sbjct: 518 LDQQSKGWQSPKQKSLDQQIKD---------WLSPKRHSVDKQAQLNQTKEQLPDQQAED 568

Query: 461 EESQKENMPCGETAEFKQK-QSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRE 519
           ++++ E  P G++ + + K Q  +K +  K+Q QD QTE +  ++       +  K Q +
Sbjct: 569 QQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQE------KKSPKGQFQ 622

Query: 520 NIQQVSQKEAKHKITSADGHIESSALLKEKQRHRLHKFLCLRVGKP 565
           N+Q   Q+    K+       +S + +++ Q  + HK   L+ G+P
Sbjct: 623 NVQAEGQQAQVEKVPKLLCQ-DSESQIQQYQFWQFHKG-NLQAGQP 666


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 88/468 (18%), Positives = 163/468 (34%), Gaps = 76/468 (16%)

Query: 275  EILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESL 334
            E LD  + + L +D +  +G +   +++    N  EI  +  +AG+++       T+++ 
Sbjct: 4877 EALD--LPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNE 4934

Query: 335  SEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHL 394
            S+    E E  P  ++    +E   +  +GA  +        E                 
Sbjct: 4935 SQSP-QEPEEGPSEDDKAEGEE---EMDTGADDQDGDAAQHPE----------------- 4973

Query: 395  RSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLH 454
                EHS  +  ++  K            D+ AD   G +GP +     +   +++    
Sbjct: 4974 ----EHSEEQQQSVEEK------------DKEADEEGGENGPADQGFQPQEEEEREDSDT 5017

Query: 455  ENSLHQEESQKENMPCGETA--EFKQKQSVN------KGKQGKEQNQDSQTEAEELRKLW 506
            E  + +   +KE+  CG+T     +  Q++       + +QGKE++     +A +     
Sbjct: 5018 EEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHE 5077

Query: 507  KTHTMQQTKQQ--RENIQQVSQK--------------EAKHK---ITSADGHIESS-ALL 546
                 Q   Q+  R+N Q   +K              E  HK       D H E   A  
Sbjct: 5078 SNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQ 5137

Query: 547  KEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYA-------QRDKKHEYWFAVPQERT 599
             + Q      F  ++ G           ++  QQ +       Q +++ E      +E+ 
Sbjct: 5138 PQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQE 5197

Query: 600  DHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDI 659
            +   A   Q  PE     T          V  +  ++E  +D     A +E E    E  
Sbjct: 5198 EFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERS 5257

Query: 660  NSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYP 707
                + T    L    F+P L D +E  L  ++E+  +   PR  G P
Sbjct: 5258 RESTIHTAHQFLMDTIFQPFLKDVNE--LRQELERQLEMWQPRESGNP 5303


>gi|8922940 gamma-taxilin [Homo sapiens]
          Length = 528

 Score = 38.5 bits (88), Expect = 0.026
 Identities = 43/229 (18%), Positives = 99/229 (43%), Gaps = 28/229 (12%)

Query: 477 KQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSA 536
           KQ Q V +    + ++  +     +L  L +         + EN+QQ  ++E + K  +A
Sbjct: 183 KQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATA 242

Query: 537 DGHIESSALLKEKQRHRLHKFLC----LRVGKPMRKTFVSQASATMQQYAQRDKKHEYWF 592
              I    +  + ++H +H        + +G+ ++K         ++QYA R++  +  F
Sbjct: 243 HFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKK--------LIEQYALREEHIDKVF 294

Query: 593 AVPQERTDHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWE 652
              +E    L    +Q + ++  E   ++ RE  F++ +  E            +  ++E
Sbjct: 295 K-RKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATE------------SRHKYE 341

Query: 653 ITTREDINSKQVATVKADLESESFRPNLSDPSELL--LPDQIEKLTKHL 699
              ++++  KQ  ++  D + E F+  ++  +EL      ++EK+TK +
Sbjct: 342 QMKQQEVQLKQQLSLYMD-KFEEFQTTMAKSNELFTTFRQEMEKMTKKI 389


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 38.5 bits (88), Expect = 0.026
 Identities = 58/261 (22%), Positives = 105/261 (40%), Gaps = 38/261 (14%)

Query: 275  EILDSKIKESLPIDIDQLSG------RDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPR 328
            E L S   +SLP + D+ +       +  C +K       +E   +  D  + S+S  P+
Sbjct: 1296 EGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPK 1355

Query: 329  STEESLSEDVFTESELSPIREE---LVSSDE------LRQDKSSGASSES---------- 369
            S +  LS+  ++   +S    E   L+ +DE      L++D  S  SS S          
Sbjct: 1356 SPQ-GLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES 1414

Query: 370  -VQTVNQAEVESLT-VKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIA 427
             V ++ +A+  +L   KSE    P  +  +      +  +L    ++   E  IKE Q  
Sbjct: 1415 TVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEE 1474

Query: 428  DNFQGISGPKEDSTSIKGNSDQDSFLHENSLH-------QEESQKENMPCGETAEFKQKQ 480
                     ++D  S K + ++  F+ + +         +E S+ EN P     + K++ 
Sbjct: 1475 RKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSP---VPQRKRRT 1531

Query: 481  SVNKGKQGKEQNQDSQTEAEE 501
            SV      + + +DSQ   EE
Sbjct: 1532 SVGSSSSDEYKQEDSQGSGEE 1552


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 38.5 bits (88), Expect = 0.026
 Identities = 58/261 (22%), Positives = 105/261 (40%), Gaps = 38/261 (14%)

Query: 275  EILDSKIKESLPIDIDQLSG------RDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPR 328
            E L S   +SLP + D+ +       +  C +K       +E   +  D  + S+S  P+
Sbjct: 1296 EGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPK 1355

Query: 329  STEESLSEDVFTESELSPIREE---LVSSDE------LRQDKSSGASSES---------- 369
            S +  LS+  ++   +S    E   L+ +DE      L++D  S  SS S          
Sbjct: 1356 SPQ-GLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES 1414

Query: 370  -VQTVNQAEVESLT-VKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIA 427
             V ++ +A+  +L   KSE    P  +  +      +  +L    ++   E  IKE Q  
Sbjct: 1415 TVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEE 1474

Query: 428  DNFQGISGPKEDSTSIKGNSDQDSFLHENSLH-------QEESQKENMPCGETAEFKQKQ 480
                     ++D  S K + ++  F+ + +         +E S+ EN P     + K++ 
Sbjct: 1475 RKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSP---VPQRKRRT 1531

Query: 481  SVNKGKQGKEQNQDSQTEAEE 501
            SV      + + +DSQ   EE
Sbjct: 1532 SVGSSSSDEYKQEDSQGSGEE 1552


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,908,551
Number of Sequences: 37866
Number of extensions: 1548434
Number of successful extensions: 7500
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 364
Number of HSP's that attempted gapping in prelim test: 6369
Number of HSP's gapped (non-prelim): 1335
length of query: 846
length of database: 18,247,518
effective HSP length: 111
effective length of query: 735
effective length of database: 14,044,392
effective search space: 10322628120
effective search space used: 10322628120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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