Search of human proteins with 193804867

Search of human proteins with 193804867

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|193804867 nucleolar and spindle associated protein 1 isoform
3 [Homo sapiens]
         (402 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|193804867 nucleolar and spindle associated protein 1 isoform ...   799   0.0  
gi|193804865 nucleolar and spindle associated protein 1 isoform ...   780   0.0  
gi|17505234 nucleolar and spindle associated protein 1 isoform 2...   773   0.0  
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom...    43   6e-04
gi|125656165 THO complex 2 [Homo sapiens]                              39   0.006
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    39   0.006
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         39   0.011
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  38   0.014
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       37   0.024
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ...    37   0.024
gi|7661950 SH2 domain binding protein 1 [Homo sapiens]                 37   0.024
gi|21396500 HIRA interacting protein 3 [Homo sapiens]                  37   0.032
gi|7661936 scaffold attachment factor B2 [Homo sapiens]                37   0.032
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    37   0.041
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    37   0.041
gi|87162461 fragile X mental retardation 2 [Homo sapiens]              37   0.041
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     36   0.054
gi|60097902 filaggrin [Homo sapiens]                                   36   0.054
gi|39995093 parathyroid hormone-like hormone isoform 1 prepropro...    36   0.054
gi|39995091 parathyroid hormone-like hormone isoform 1 prepropro...    36   0.054
gi|39995089 parathyroid hormone-like hormone isoform 2 prepropro...    36   0.054
gi|4506269 parathyroid hormone-like hormone isoform 2 preproprot...    36   0.054
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    36   0.054
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    36   0.054
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           36   0.054
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]           36   0.054
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...    36   0.054
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...    36   0.054
gi|58530840 desmoplakin isoform I [Homo sapiens]                       36   0.070
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ...    36   0.070

>gi|193804867 nucleolar and spindle associated protein 1 isoform 3
           [Homo sapiens]
          Length = 402

 Score =  799 bits (2063), Expect = 0.0
 Identities = 402/402 (100%), Positives = 402/402 (100%)

Query: 1   MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
           MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS
Sbjct: 1   MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60

Query: 61  ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
           ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE
Sbjct: 61  ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120

Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
           KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI
Sbjct: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180

Query: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS 240
           TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS
Sbjct: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS 240

Query: 241 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 300
           VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT
Sbjct: 241 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 300

Query: 301 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAGKLKPWGQSKENNYLNQHVNRINFY 360
           PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAGKLKPWGQSKENNYLNQHVNRINFY
Sbjct: 301 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAGKLKPWGQSKENNYLNQHVNRINFY 360

Query: 361 KKTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGLILAED 402
           KKTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGLILAED
Sbjct: 361 KKTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGLILAED 402


>gi|193804865 nucleolar and spindle associated protein 1 isoform 1
           [Homo sapiens]
          Length = 441

 Score =  780 bits (2013), Expect = 0.0
 Identities = 402/441 (91%), Positives = 402/441 (91%), Gaps = 39/441 (8%)

Query: 1   MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
           MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS
Sbjct: 1   MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60

Query: 61  ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
           ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE
Sbjct: 61  ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120

Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
           KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI
Sbjct: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180

Query: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS 240
           TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS
Sbjct: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS 240

Query: 241 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 300
           VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT
Sbjct: 241 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 300

Query: 301 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAA------------------------- 335
           PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAA                         
Sbjct: 301 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDL 360

Query: 336 --------------GKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 381
                         GKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ
Sbjct: 361 KASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 420

Query: 382 ERKEKKAKVLGMRRGLILAED 402
           ERKEKKAKVLGMRRGLILAED
Sbjct: 421 ERKEKKAKVLGMRRGLILAED 441


>gi|17505234 nucleolar and spindle associated protein 1 isoform 2
           [Homo sapiens]
          Length = 440

 Score =  773 bits (1996), Expect = 0.0
 Identities = 401/441 (90%), Positives = 401/441 (90%), Gaps = 40/441 (9%)

Query: 1   MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
           MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS
Sbjct: 1   MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60

Query: 61  ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
           ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE
Sbjct: 61  ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120

Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
           KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI
Sbjct: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180

Query: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS 240
           TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELK QPINKGGVRTPVPPRGRLS
Sbjct: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELK-QPINKGGVRTPVPPRGRLS 239

Query: 241 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 300
           VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT
Sbjct: 240 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 299

Query: 301 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAA------------------------- 335
           PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAA                         
Sbjct: 300 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDL 359

Query: 336 --------------GKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 381
                         GKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ
Sbjct: 360 KASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 419

Query: 382 ERKEKKAKVLGMRRGLILAED 402
           ERKEKKAKVLGMRRGLILAED
Sbjct: 420 ERKEKKAKVLGMRRGLILAED 440


>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
            containing 1 isoform c [Homo sapiens]
          Length = 1462

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 52/207 (25%), Positives = 86/207 (41%), Gaps = 21/207 (10%)

Query: 95   VRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDS 154
            VR  PD +Q H  ++ S P +   H+     + RA A+ P    E+    N   + N  S
Sbjct: 1230 VRAGPDRRQ-HPSLESSYPPDL--HKSSPHGEKRAHARDPKGSREYSRQPNEHHTWNGTS 1286

Query: 155  KVPSEG--KKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEE 212
            + P  G  +      E  +  + +R A      ++  E   +   S D  +ER++KH E+
Sbjct: 1287 RKPDSGACRPKDRAPEGRRDAQAERAAAANGPKRRSPEKRREGTRSADNTLERREKH-EK 1345

Query: 213  HNSMNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKR 272
               ++  +++  +    R   P R R S+    + QRRS  R  G          GS +R
Sbjct: 1346 RRDVSPERRRERSPTRRRDGSPSRRRRSLERL-LEQRRSPERRRG----------GSPER 1394

Query: 273  SAISAAKTGVRFSAATKDNEHKRSLTK 299
                 AK+  R  A + +   +RSL K
Sbjct: 1395 ----RAKSTDRRRARSPERRRERSLDK 1417


>gi|125656165 THO complex 2 [Homo sapiens]
          Length = 1593

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 58/275 (21%), Positives = 101/275 (36%), Gaps = 35/275 (12%)

Query: 50   GNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIK 109
            G      S  SAS  DE+  + +++   ER   G   K   +  +     +S   +S   
Sbjct: 1205 GGGPSSSSIGSASKSDESSTEETDKSR-ERSQCG--VKAVNKASSTTPKGNSSNGNSGSN 1261

Query: 110  ISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDES 169
             +   +  + EK + ++     K P+   E +              +  +GK+    +  
Sbjct: 1262 SNKAVKENDKEKGKEKEKEKKEKTPATTPEARV-------------LGKDGKEKPKEERP 1308

Query: 170  SKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYI---------------ERKKKHFEEHN 214
            +K  K + T   TP   K  E   KE ++ D+                 ER+K+   E +
Sbjct: 1309 NKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERD 1368

Query: 215  SMNELKQQPINKGGVRTPVPPRGRLSVASTPISQ-RRSQGR---SCGPASQSTLGLKGSL 270
               E+K +   KGG +TPV    +  V  + I +  R Q R      P+   +  +K SL
Sbjct: 1369 IAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSSTVKDSL 1428

Query: 271  KRSAISAAKTGVRFSAATKDNEHKRSLTKTPARKS 305
                 S+AK  +  +        +R + K    KS
Sbjct: 1429 IELKESSAKLYINHTPPPLSKSKEREMDKKDLDKS 1463



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 58/282 (20%), Positives = 103/282 (36%), Gaps = 31/282 (10%)

Query: 114  TEFQNHEKQESQ-DLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKP 172
            TE  +  ++ SQ  ++A  K  S   +   +    +SG+  +K   E  K    ++  + 
Sbjct: 1224 TEETDKSRERSQCGVKAVNKASSTTPKGNSSNG--NSGSNSNKAVKENDKEKGKEKEKE- 1280

Query: 173  GKNKRTAITTPNFKKL----HEAHFKEMESIDQYIERKKKHFEEHNSMNEL--KQQPINK 226
             K ++T  TTP  + L     E   +E  + D+     K+   + +   E   K++    
Sbjct: 1281 -KKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKD 1339

Query: 227  GGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGV-RFS 285
               +T VP     S       +  S+ R      +S   +KG  K     + K+ V R  
Sbjct: 1340 EKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKENVKGGEKTPVSGSLKSPVPRSD 1399

Query: 286  AATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAGKLKPWGQSK 345
                + E KR    T    S   TV     +    L     K    ++      P  +SK
Sbjct: 1400 IPEPEREQKRRKIDTHPSPSHSSTVKDSLIE----LKESSAKLYINHTPP----PLSKSK 1451

Query: 346  ENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKK 387
            E     + +++             +   E+ KK E++RKE+K
Sbjct: 1452 EREMDKKDLDKSR-----------ERSREREKKDEKDRKERK 1482


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 46/215 (21%), Positives = 85/215 (39%), Gaps = 23/215 (10%)

Query: 59  TSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQN 118
           T  +    +E + S+ EE + + +   TK +   K     P  Q        S+ ++  +
Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSS 477

Query: 119 HEKQESQDLRATAK----------VPSPPDEHQE--AENAVSSGNRDSKVPSEGK-KSLY 165
            E++E +  ++  K           PS P   ++  AE++ SS + DS    E K K   
Sbjct: 478 SEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKG 537

Query: 166 TDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPIN 225
           +     P  N  +A+T  N K    +  +E        E KKK     +    LK++  N
Sbjct: 538 SPRPQAPKANGTSALTAQNGKAAKNSEEEE--------EEKKKAAVVVSKSGSLKKRKQN 589

Query: 226 KGG--VRTPVPPRGRLSVASTPISQRRSQGRSCGP 258
           +      TP   + +L   +T   +++ + R+  P
Sbjct: 590 EAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSP 624


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 38.5 bits (88), Expect = 0.011
 Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 28/191 (14%)

Query: 49  KGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNH-SE 107
           + ++ +DE   +     E E   S++E+   +P                D DS+ N  S 
Sbjct: 44  RASDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQ-------------DQDSEVNELSR 90

Query: 108 IKISNPTEFQNHEKQESQ--DLRATAK-VPSPPDEHQEAENAVSSGNRDSKVPSEGKKSL 164
              S+P E +  E +E +  DLR  A  V    DEH+         + D +VP E   ++
Sbjct: 91  GPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHEL--------DYDEEVPEEPAPAV 142

Query: 165 YTDESSKPGK--NKRTAITTPNFK-KLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQ 221
             DE+ K G   ++     TP  + K       E ES++   E+KK+  +      E+  
Sbjct: 143 QEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDD 202

Query: 222 QPINKGGVRTP 232
             + +G V+ P
Sbjct: 203 DDLEEGEVKDP 213


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 57/345 (16%), Positives = 125/345 (36%), Gaps = 32/345 (9%)

Query: 51  NENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKI 110
           + + D S  S SS D ++ + + +E+++++   H   +R+  K  +     ++  S+   
Sbjct: 201 SSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKK-----KRKKSKKSA 255

Query: 111 SNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESS 170
           S+ +E +N E Q    +R     P P +     ++   +  ++ K     ++      +S
Sbjct: 256 SSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNS 315

Query: 171 KPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVR 230
           +P   +R  + T + +K+     +   +  +   R +  F                   R
Sbjct: 316 QPASYQRRLLVTRSGRKIKGRGPRRYRTPSR--SRSRDRFR------------------R 355

Query: 231 TPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGV----RFSA 286
           +  PP  R  +       R S G       +S L      +RS +   +  +      S 
Sbjct: 356 SETPPHWRQEMQRAQ-RMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSE 414

Query: 287 ATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAGKLKPWGQSKE 346
           +      K    K     S    +   + K +      K +  + + +  K K   + ++
Sbjct: 415 SPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERD 474

Query: 347 NNYLNQHVNRINFYKKTYKQPHLQTKEEQ--RKKREQERKEKKAK 389
           + +      R+    K     +++ KE+Q   K ++QER   K K
Sbjct: 475 SKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEK 519



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 32/180 (17%), Positives = 67/180 (37%), Gaps = 9/180 (5%)

Query: 44  KHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQ 103
           +H+  K  E    +Q+ +  CD T+ + S       +        R R +T   D    +
Sbjct: 529 EHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSK 588

Query: 104 NHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKS 163
            +   +     E++   +  S++ R         D  +   ++ SS   +S+  ++ K  
Sbjct: 589 EYHRYR---EQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDK-- 643

Query: 164 LYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHF---EEHNSMNELK 220
            Y ++ SK    K  + +          H     S ++  +R +  F   ++ +  NELK
Sbjct: 644 -YRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELK 702



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 50/279 (17%), Positives = 105/279 (37%), Gaps = 39/279 (13%)

Query: 126 DLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNF 185
           +L   +KV     +  ++ ++ SS + DS   S+ + S  + +S    + K     +   
Sbjct: 176 ELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEK-----SKKR 230

Query: 186 KKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVR---TPVPPRGRLSVA 242
           KK H  + ++ +   +  ++ KK     +    L+ QP  +  VR    P  P  R  + 
Sbjct: 231 KKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQP--QSTVRPEEIPPIPENRFLMR 288

Query: 243 STP--------ISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHK 294
            +P         ++ R + R C P +      +   +R  ++ +   ++     +     
Sbjct: 289 KSPPKADEKERKNRERERERECNPPNSQPASYQ---RRLLVTRSGRKIKGRGPRRYRTPS 345

Query: 295 RSLTKTPARKSAHVTVSGGTPK--GEAVLGTHKLKTITGNSAAGKLKPW--GQSKENNYL 350
           RS ++   R+S        TP    + +    +++  +G       + W  G   E N +
Sbjct: 346 RSRSRDRFRRSE-------TPPHWRQEMQRAQRMRVSSG-------ERWIKGDKSELNEI 391

Query: 351 NQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAK 389
            ++       K+     H    E   +K E+E+K K  K
Sbjct: 392 KENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHK 430


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 78/389 (20%), Positives = 136/389 (34%), Gaps = 47/389 (12%)

Query: 33  TKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRC 92
           T ++    G I  E  K  E +++     S  ++ E +   + EAER  L    + R R 
Sbjct: 223 TVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLE--AEERERI 280

Query: 93  KTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDL-RATAKVPSPPDEHQEAENAVSSGN 151
           K  + D       + I+       Q  E++E+++  R   +     +E Q  +       
Sbjct: 281 KAEQ-DKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAA 339

Query: 152 RDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFK-EMESIDQYIERKKKHF 210
            + +   E +K    +      + KR A      +   E   K E +  ++ +E KK   
Sbjct: 340 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAM 399

Query: 211 EEHNSMNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSL 270
           +E     E  +Q I    V        +L  A       + QG   G   Q+    +  L
Sbjct: 400 QETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVL-----KKQGEEKGTKVQAK---REKL 451

Query: 271 KRSAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLK--- 327
           +    +  K  ++     KD E K  +     RK     V   +  GE +  THKLK   
Sbjct: 452 QEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK--SQNGEFM--THKLKHTE 507

Query: 328 ----------TITGNSAAG--KLKPWGQSKENNYLNQHVNRINFYKKTYKQPH------- 368
                     ++    A G  +++   + +E            F K   KQ         
Sbjct: 508 NTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEE 567

Query: 369 LQTKEEQRKK--------REQERKEKKAK 389
           L+ K E+R+K        R+QE  ++K +
Sbjct: 568 LKKKREERRKVLEEEEQRRKQEEADRKLR 596



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 37/163 (22%), Positives = 64/163 (39%), Gaps = 23/163 (14%)

Query: 44  KHEARKGNENQDESQTSASSCD----ETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDP 99
           K E R+    ++E +      D    E E +   +EE ER+      + R++     +  
Sbjct: 571 KREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR-AEAAEKRQKMPEDGLSD 629

Query: 100 DSQQ------NHSEIKISNPTEFQNHEKQESQDLRAT--AKVPSPPDEHQEAENAVSSGN 151
           D +         S +KI    EF N   Q+S  +++T  A + S  D   E   +   G 
Sbjct: 630 DKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGT 689

Query: 152 RDSK----------VPSEGKKSLYTDESSKPGKNKRTAITTPN 184
           + +K          VP+EG +++ +        +  TA  TPN
Sbjct: 690 KSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPN 732


>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
           sapiens]
          Length = 956

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 9/94 (9%)

Query: 298 TKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAGK-LKPWGQSKENNYLNQHVNR 356
           T TP R+     V G T K       +KL+        GK LK   + +E   L +   R
Sbjct: 314 TSTPLRRITKKFVKGSTEK-------NKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKR 366

Query: 357 INFYKKTYKQPHLQTKE-EQRKKREQERKEKKAK 389
                K  K+   + KE E+R+KRE++ KEK  K
Sbjct: 367 AKEEAKKKKEEEKELKEKERREKREKDEKEKAEK 400



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 28/122 (22%), Positives = 46/122 (37%), Gaps = 3/122 (2%)

Query: 16  DLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQE 75
           D + L K L LRA     + LK      K EA+K  E + E +         + +   +E
Sbjct: 340 DQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER---REKREKDEKE 396

Query: 76  EAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPS 135
           +AE+Q L    +  R+        + ++   E ++    +    EK E        K P 
Sbjct: 397 KAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQ 456

Query: 136 PP 137
            P
Sbjct: 457 AP 458


>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
          Length = 1173

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 30/146 (20%), Positives = 54/146 (36%), Gaps = 9/146 (6%)

Query: 34   KLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCK 93
            +L  ++KG IK +A   + +    +      DE   + SN      +      + R++C 
Sbjct: 999  RLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDED-----EQRKKCA 1053

Query: 94   TVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRD 153
            +   D D  QN S  +  +P   +     +  D    ++   P    Q    +V SG   
Sbjct: 1054 SSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSH 1113

Query: 154  SKVPSEGKK----SLYTDESSKPGKN 175
            S V     +    S  +D  S+ G +
Sbjct: 1114 SGVSENDSRPASPSAESDHESERGSD 1139


>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
          Length = 556

 Score = 37.0 bits (84), Expect = 0.032
 Identities = 72/337 (21%), Positives = 116/337 (34%), Gaps = 55/337 (16%)

Query: 42  YIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPD- 100
           Y+ H  R   E  +E Q      +E  +++   E A R+    +TK  +R  T   DP+ 
Sbjct: 33  YLAHSGRSHLE-PEEKQALKRLVEEELLKMQVDEAASREDKLDLTKKGKRPPTPCSDPER 91

Query: 101 -----SQQNHSEIKISNPTEFQNHEK----------QESQDLRATAKVPSPPDEHQEAEN 145
                + ++ S  + S+P  F    K          +E    RA+  V    DE ++ + 
Sbjct: 92  KRFRFNSESESGSEASSPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEESSDEERQRDL 151

Query: 146 AVSSGNRDSKVPSEG-----------------------KKSLYTDESSKPGKNKRTAITT 182
               G   S+   +G                       K++    E S+    +RTA   
Sbjct: 152 PAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSRKQAREESEESEAEPVQRTAKKV 211

Query: 183 PNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLSVA 242
              K        E ES ++ + +KK+  EE     E K++   KG  +      GR   A
Sbjct: 212 EGNKGTKSLKESEQESEEEILAQKKEQREEEVEEEE-KEEDEEKGDWKPRTRSNGRRKSA 270

Query: 243 STPISQRRSQGRSCGPASQSTLGLKGS-----LKRSAISAAKTGVRFSAATKDNEHKRSL 297
                    + RSC   SQ+   L  S      K +A S   +G       +     R+ 
Sbjct: 271 --------REERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDRTQ 322

Query: 298 TKTPARKSAHVTVSGGTPKGE-AVLGTHKLKTITGNS 333
            K   R S        + KGE    G+ K+  +   S
Sbjct: 323 LKGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGSTS 359


>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
          Length = 953

 Score = 37.0 bits (84), Expect = 0.032
 Identities = 37/171 (21%), Positives = 75/171 (43%), Gaps = 12/171 (7%)

Query: 55  DESQTSASSCDETEI--QISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKIS- 111
           DE+    S    TE+  ++ + E+A+ +P G     R+ C+  +    S   H  ++I  
Sbjct: 459 DEATKCISHLHRTELHGRMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKI 518

Query: 112 NPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSK 171
             T  +  EK E ++ +    +     +  E +   ++ +R +K  S G +     + SK
Sbjct: 519 EKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSK 578

Query: 172 PGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQ 222
            G+   +  TT   K+      +  +S D+  E K+K   +  S +++K+Q
Sbjct: 579 -GEPVISVKTTSRSKE------RSSKSQDRKSESKEK--RDILSFDKIKEQ 620


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 36.6 bits (83), Expect = 0.041
 Identities = 38/166 (22%), Positives = 70/166 (42%), Gaps = 23/166 (13%)

Query: 30  LRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQP-------L 82
           +RA + LK  +   + E  + ++ ++E         E  I    +EE E  P       +
Sbjct: 261 VRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMM 320

Query: 83  GHVTKTRRRCKTV--------RVDPDSQQNH-------SEIKISNPTEFQNHEKQESQDL 127
               KTR + + V        R   +++++H        E+K ++P E +  E + SQ L
Sbjct: 321 DERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGL 380

Query: 128 RATAKVPSPPDEHQEAENA-VSSGNRDSKVPSEGKKSLYTDESSKP 172
           +  +K PSPP   ++ + A + +    +    E    L T E+S P
Sbjct: 381 KEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSP 426



 Score = 32.7 bits (73), Expect = 0.60
 Identities = 68/344 (19%), Positives = 121/344 (35%), Gaps = 77/344 (22%)

Query: 7    EELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDE 66
            +E  S   S +Q    S    A    T+ L+  +G     + K  E ++    +A+    
Sbjct: 694  KERTSTSSSSVQARRLSQPESAEKHVTQRLQPERG-----SPKKCEAEEAEPPAATQPQT 748

Query: 67   TEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPT-----EFQNHEK 121
            +E Q S+  E+ER  + H  + +       V  D+ +N  E  +  P      +  N ++
Sbjct: 749  SETQTSHLPESER--IHHTVEEKEE-----VTMDTSENRPENDVPEPPMPIADQVSNDDR 801

Query: 122  QESQDLRATAKVPSPPDEHQE------AENAVSSGNRDSKVPSEGKKSLYTDESSKPGKN 175
             E        K  S P   +       A   V +GN D++    G+K  +   ++   K 
Sbjct: 802  PEGSVEDEEKKESSLPKSFKRKISVVSATKGVPAGNSDTEGGQPGRKRRWGASTATTQKK 861

Query: 176  KRTAITTPNFKKL------------------------------------HEAHFKEMESI 199
               +ITT + K L                                    H+   K   ++
Sbjct: 862  PSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTV 921

Query: 200  DQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPA 259
             Q +  + +   +     E K+          PVPP+  + VA  P ++           
Sbjct: 922  TQVVPAEGQENGQREEEEEEKEPE-----AEPPVPPQVSVEVALPPPAEHE--------V 968

Query: 260  SQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTPAR 303
             + TLG   +L R +IS  K+GV   + T D+  + +   +P R
Sbjct: 969  KKVTLG--DTLTRRSISQQKSGV---SITIDDPVRTAQVPSPPR 1007



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 45/223 (20%), Positives = 91/223 (40%), Gaps = 27/223 (12%)

Query: 9   LDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNEN-----QDESQTSASS 63
           L +L+ +DL+   +  GL  + + + L+K LKG +  E  + +       Q  SQ     
Sbjct: 72  LQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQPNSQIGEEM 131

Query: 64  CDETEIQ--ISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSE-IKISNPTEFQNH- 119
              + I+  +  Q+E  RQ L    +     +    + + +  H E +    P +FQ+  
Sbjct: 132 SQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASLLPPDFQSSL 191

Query: 120 EKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGK---------KSLYTDESS 170
           E+ E +  R + +  S   E +        G+ D + P +G+         ++    E S
Sbjct: 192 ERPELELSRHSPRKSSSISEEK--------GDSDDEKPRKGERRSSRVRQARAAKLSEGS 243

Query: 171 KPGKNKRTAIT-TPNFKKLHEAHFKEMESIDQYIERKKKHFEE 212
           +P + +    T + N +   + + K  E  ++  E ++   EE
Sbjct: 244 QPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEE 286


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 36.6 bits (83), Expect = 0.041
 Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 27/202 (13%)

Query: 32  ATKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEE------------AER 79
           A K  K +K  +K + +K +  +D   T A S D  + +   +++             ++
Sbjct: 306 AKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKK 365

Query: 80  QPLGHVTKT---------RRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRAT 130
            P    T++          R  K    + D +++  +I  S  +E +   K+  +D +  
Sbjct: 366 YPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKD 425

Query: 131 AKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHE 190
            K  S  D  +  +N   S + DS+   + KK    ++  K  K+ +      + KK   
Sbjct: 426 KK-DSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGK--KDSKKDDKKKDAKK--N 480

Query: 191 AHFKEMESIDQYIERKKKHFEE 212
           A   EMES D  +++ KKH +E
Sbjct: 481 AESTEMES-DLELKKDKKHSKE 501


>gi|87162461 fragile X mental retardation 2 [Homo sapiens]
          Length = 1311

 Score = 36.6 bits (83), Expect = 0.041
 Identities = 66/304 (21%), Positives = 108/304 (35%), Gaps = 31/304 (10%)

Query: 46  EARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNH 105
           +A  G+ +  ES++S+ S  +TE   ++ E  E            R  T   +P S    
Sbjct: 479 QASGGSGSSSESESSSESDSDTESSTTDSESNEAP----------RVATPEPEPPSTNKW 528

Query: 106 SEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLY 165
              K  N    QN      Q+      +  PP   Q  E  +      S+VP+E K+   
Sbjct: 529 QLDKWLNKVTSQNKSFICGQNETPMETISLPPPIIQPMEVQMKVKTNASQVPAEPKERPL 588

Query: 166 TD---ESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKK--KHFEEHNSMNEL- 219
                E ++P    R     P  K L        E++ Q    KK  K  E++ S +E  
Sbjct: 589 LSLIREKARP----RPTQKIPETKALKHKLSTTSETVSQRTIGKKQPKKVEKNTSTDEFT 644

Query: 220 -------KQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKR 272
                     P  K  V    PPRGR + A+      R + R   P +      +G  K 
Sbjct: 645 WPKPNITSSTPKEKESVELHDPPRGR-NKATAHKPAPRKEPRPNIPLAPEKKKYRGPGK- 702

Query: 273 SAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTH-KLKTITG 331
             +  ++  +   ++T D+   +  T         +   G T K + + G    L T+  
Sbjct: 703 -IVPKSREFIETDSSTSDSNTDQEETLQIKVLPPCIISGGNTAKSKEICGASLTLSTLMS 761

Query: 332 NSAA 335
           +S +
Sbjct: 762 SSGS 765


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 52/263 (19%), Positives = 106/263 (40%), Gaps = 30/263 (11%)

Query: 44  KHEARKGNENQDESQTSASSCDETEIQISNQEEA----ERQPLGHVTKTRRRCKTV--RV 97
           K ++R  + +  +S++ +   D+ E +I N +       R P  H +K++ R ++   RV
Sbjct: 252 KEKSRSRSHSAGKSRSKSK--DQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRV 309

Query: 98  DPDSQQNHSEIKISNPTEFQNHEKQESQD---LRATAKVPSPPDEHQEAENAVSSGNRD- 153
           + + + + S  +    +  Q+  +  S+     R+ ++  S         +   S +R  
Sbjct: 310 EEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSR 369

Query: 154 SKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEH 213
           S+  SE  +   +   SK G +K+        KK  +    +  S  + + ++++H +  
Sbjct: 370 SRSKSERSRKRGSKRDSKAGSSKK--------KKKEDTDRSQSRSPSRSVSKEREHAKSE 421

Query: 214 NSMNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRS 273
           +S  E + +  N  G       R R +  S P     S+ RS   ++  T     S  RS
Sbjct: 422 SSQREGRGESEN-AGTNQETRSRSRSNSKSKP--NLPSESRSRSKSASKTRSRSKSRSRS 478

Query: 274 AISAAKTGVRFSAATKDNEHKRS 296
           A        R  + ++   H RS
Sbjct: 479 A-------SRSPSRSRSRSHSRS 494


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 28/125 (22%), Positives = 53/125 (42%), Gaps = 6/125 (4%)

Query: 56  ESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTE 115
           E   S+     +++  S  E   + PL      +RR   V  D DS+ +  + +  + + 
Sbjct: 258 ERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSA 317

Query: 116 FQNHEKQESQDLRATAKVPSPPDEHQ-----EAENAVSSGNRDSKVPSEGK-KSLYTDES 169
            +NH     +  R  ++ P   DE +      A+++  SG R ++  S G+  S +    
Sbjct: 318 SRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQAR 377

Query: 170 SKPGK 174
           S PG+
Sbjct: 378 SSPGE 382



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 7/121 (5%)

Query: 48   RKGNENQDESQTSASSCDE--TEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNH 105
            R   ++ D S+ S S   E  T   IS   +A +       ++RR+  +V  D DS+ + 
Sbjct: 2842 RNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHS 2901

Query: 106  SEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQ-----EAENAVSSGNRDSKVPSEG 160
             + +  + +  +NH     + LR  ++ P    E +      A+++  SG R ++  S G
Sbjct: 2902 EDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGG 2961

Query: 161  K 161
            +
Sbjct: 2962 Q 2962



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 31/135 (22%), Positives = 58/135 (42%), Gaps = 8/135 (5%)

Query: 48   RKGNENQDESQTSASSCDE--TEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNH 105
            R   ++ D S+ S S   E  T   IS   +A +       ++RR+  +V  D DS+ + 
Sbjct: 3166 RNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHS 3225

Query: 106  SEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQ-----EAENAVSSGNRDSKVPSEG 160
             + +  + +  +NH     +  R  ++ P    E +      A+ +  SG R ++  S G
Sbjct: 3226 EDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGG 3285

Query: 161  K-KSLYTDESSKPGK 174
            +  S +    S PG+
Sbjct: 3286 QAASSHEQARSSPGE 3300



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 29/138 (21%), Positives = 62/138 (44%), Gaps = 10/138 (7%)

Query: 46   EARKGNENQDESQTSASSCDETEIQISNQEEAE---RQPLGHVTKTRRRCKTVRVDPDSQ 102
            + R   ++ D S+ S S   E   +  +   ++    +  G  T +RR+  +V  D DS+
Sbjct: 1543 QTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKT-SRRQGSSVSQDRDSE 1601

Query: 103  QNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQ-----EAENAVSSGNRDSKVP 157
             +  + +  + +  +NH     +  R  ++ P    E +      AE++  SG R ++  
Sbjct: 1602 GHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETS 1661

Query: 158  SEGKKSLYTDES-SKPGK 174
            S G+ +   +++ S PG+
Sbjct: 1662 SGGQAASSQEQARSSPGE 1679


>gi|39995093 parathyroid hormone-like hormone isoform 1
           preproprotein [Homo sapiens]
          Length = 177

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%)

Query: 341 WGQSKENNYLNQHVNRINFYK-KTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGL 397
           +G   E  YL Q  N++  YK +  K P  + K +  K++EQE+K+++ +   +  G+
Sbjct: 95  FGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGV 152


>gi|39995091 parathyroid hormone-like hormone isoform 1
           preproprotein [Homo sapiens]
          Length = 177

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%)

Query: 341 WGQSKENNYLNQHVNRINFYK-KTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGL 397
           +G   E  YL Q  N++  YK +  K P  + K +  K++EQE+K+++ +   +  G+
Sbjct: 95  FGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGV 152


>gi|39995089 parathyroid hormone-like hormone isoform 2
           preproprotein [Homo sapiens]
          Length = 175

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%)

Query: 341 WGQSKENNYLNQHVNRINFYK-KTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGL 397
           +G   E  YL Q  N++  YK +  K P  + K +  K++EQE+K+++ +   +  G+
Sbjct: 95  FGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGV 152


>gi|4506269 parathyroid hormone-like hormone isoform 2 preproprotein
           [Homo sapiens]
          Length = 175

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%)

Query: 341 WGQSKENNYLNQHVNRINFYK-KTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGL 397
           +G   E  YL Q  N++  YK +  K P  + K +  K++EQE+K+++ +   +  G+
Sbjct: 95  FGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGV 152


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 41/214 (19%), Positives = 85/214 (39%), Gaps = 34/214 (15%)

Query: 120 EKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDE--SSKPGKNKR 177
           E++E    ++  K  +P  + +E E     G  + +   EG KS   +E  S K G +++
Sbjct: 502 EEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEK 561

Query: 178 TAITTPNFKKLHEAHFKEMESIDQY-IERKKKHFEEHNSM--------NELKQQPINKGG 228
                   +   EA  +E E+ ++  +E K +       +         E  + P+ K  
Sbjct: 562 EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSP 621

Query: 229 V---------RTPVPPRGRLSVASTPISQR----------RSQGRSCGPASQSTL--GLK 267
           V         ++PV  +G+  V  +P+ ++            +G+S  P S+S +    K
Sbjct: 622 VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS--PVSKSPVEEKAK 679

Query: 268 GSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTP 301
             + +S +  AK+        +  E ++ + + P
Sbjct: 680 SPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAP 713



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 64/311 (20%), Positives = 110/311 (35%), Gaps = 50/311 (16%)

Query: 36  LKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTV 95
           +KA    +K E  +G + ++E Q      DE   +    EE   +  G   K     +  
Sbjct: 513 VKATAPEVKEE--EGEKEEEEGQEEEEEEDEGA-KSDQAEEGGSEKEGSSEKEEGEQEEG 569

Query: 96  RVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSK 155
             + +++   +E K     E ++ E    ++L A AKV  P    ++A++ V       K
Sbjct: 570 ETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP----EKAKSPV------PK 619

Query: 156 VPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNS 215
            P E K      +S    K K     +P                   +E K K     + 
Sbjct: 620 SPVEEKGKSPVPKSPVEEKGKSPVPKSP-------------------VEEKGKSPVPKSP 660

Query: 216 MNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAI 275
           + E  + P++K    +PV  + +  V  +P+ + +         S++ +G KG  K    
Sbjct: 661 VEEKGKSPVSK----SPVEEKAKSPVPKSPVEEAK---------SKAEVG-KGEQKEEEE 706

Query: 276 SAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAA 335
              K   +     K  E  + +   P +K A   V       E V  T  +K        
Sbjct: 707 KEVKEAPKEEKVEKKEEKPKDV---PEKKKAESPVK-EEAVAEVVTITKSVKVHLEKETK 762

Query: 336 GKLKPWGQSKE 346
            + KP  Q KE
Sbjct: 763 EEGKPLQQEKE 773


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 41/214 (19%), Positives = 85/214 (39%), Gaps = 34/214 (15%)

Query: 120 EKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDE--SSKPGKNKR 177
           E++E    ++  K  +P  + +E E     G  + +   EG KS   +E  S K G +++
Sbjct: 126 EEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEK 185

Query: 178 TAITTPNFKKLHEAHFKEMESIDQY-IERKKKHFEEHNSM--------NELKQQPINKGG 228
                   +   EA  +E E+ ++  +E K +       +         E  + P+ K  
Sbjct: 186 EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSP 245

Query: 229 V---------RTPVPPRGRLSVASTPISQR----------RSQGRSCGPASQSTL--GLK 267
           V         ++PV  +G+  V  +P+ ++            +G+S  P S+S +    K
Sbjct: 246 VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS--PVSKSPVEEKAK 303

Query: 268 GSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTP 301
             + +S +  AK+        +  E ++ + + P
Sbjct: 304 SPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAP 337



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 64/311 (20%), Positives = 110/311 (35%), Gaps = 50/311 (16%)

Query: 36  LKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTV 95
           +KA    +K E  +G + ++E Q      DE   +    EE   +  G   K     +  
Sbjct: 137 VKATAPEVKEE--EGEKEEEEGQEEEEEEDEGA-KSDQAEEGGSEKEGSSEKEEGEQEEG 193

Query: 96  RVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSK 155
             + +++   +E K     E ++ E    ++L A AKV  P    ++A++ V       K
Sbjct: 194 ETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP----EKAKSPV------PK 243

Query: 156 VPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNS 215
            P E K      +S    K K     +P                   +E K K     + 
Sbjct: 244 SPVEEKGKSPVPKSPVEEKGKSPVPKSP-------------------VEEKGKSPVPKSP 284

Query: 216 MNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAI 275
           + E  + P++K    +PV  + +  V  +P+ + +         S++ +G KG  K    
Sbjct: 285 VEEKGKSPVSK----SPVEEKAKSPVPKSPVEEAK---------SKAEVG-KGEQKEEEE 330

Query: 276 SAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAA 335
              K   +     K  E  + +   P +K A   V       E V  T  +K        
Sbjct: 331 KEVKEAPKEEKVEKKEEKPKDV---PEKKKAESPVK-EEAVAEVVTITKSVKVHLEKETK 386

Query: 336 GKLKPWGQSKE 346
            + KP  Q KE
Sbjct: 387 EEGKPLQQEKE 397


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 23/127 (18%), Positives = 56/127 (44%), Gaps = 12/127 (9%)

Query: 51  NENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKI 110
           +E++D++  S  + D +E + SN++++ R+       +  R  +    P S ++ S  + 
Sbjct: 172 DEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRS 231

Query: 111 SNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESS 170
            + +  Q+  +  S+            +  +   +   S +R  +  S  +K  Y+  SS
Sbjct: 232 RSSSSSQSRSRSSSR------------ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSS 279

Query: 171 KPGKNKR 177
            P +N++
Sbjct: 280 SPERNRK 286


>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
          Length = 320

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 23/127 (18%), Positives = 56/127 (44%), Gaps = 12/127 (9%)

Query: 51  NENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKI 110
           +E++D++  S  + D +E + SN++++ R+       +  R  +    P S ++ S  + 
Sbjct: 172 DEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRS 231

Query: 111 SNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESS 170
            + +  Q+  +  S+            +  +   +   S +R  +  S  +K  Y+  SS
Sbjct: 232 RSSSSSQSRSRSSSR------------ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSS 279

Query: 171 KPGKNKR 177
            P +N++
Sbjct: 280 SPERNRK 286


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 56/269 (20%), Positives = 97/269 (36%), Gaps = 42/269 (15%)

Query: 38  ALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAE---------------RQPL 82
           ALK  +   ARK + + D++  S S  + +E    +++ ++               R PL
Sbjct: 161 ALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPL 220

Query: 83  GHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRAT---AKVPSPPDE 139
           G   K +    +   D DS+ +    K   P          S    ++     V  PP  
Sbjct: 221 GGRKKKKAPSAS---DSDSKADSDGAK-PEPVAMARSASSSSSSSSSSDSDVSVKKPPRG 276

Query: 140 HQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESI 199
            + AE  +         P     S  +D  S              +K+  EA  +E+E+ 
Sbjct: 277 RKPAEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDR------ISEWKRRDEARRRELEA- 329

Query: 200 DQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLSVAST---------PISQRR 250
                R+++  EE   + E +++   +   R       R S  S+         P+ +R 
Sbjct: 330 ----RRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPVKKRG 385

Query: 251 SQGRSCGPASQSTLGLKGSLKRSAISAAK 279
            +GR  GP S S    +  L+R A  +AK
Sbjct: 386 RKGRGRGPPSSSDSEPEAELEREAKKSAK 414



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 58/303 (19%), Positives = 109/303 (35%), Gaps = 19/303 (6%)

Query: 105 HSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSL 164
           H+      P    + E  E+     +       D    A  AV++     ++ S+     
Sbjct: 89  HASYSAPPPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDK 148

Query: 165 YTDESSKPGKNKRTAITTPNFKKLHEAHFK-EMESIDQYIERKKKHFEEHNSMNELKQQP 223
            +D S    K K  A+     K+  +A    +  S+    E   +   E    ++    P
Sbjct: 149 SSDNSGL--KRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTP 206

Query: 224 INKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVR 283
             K  VR P   RG       P+  R+ +       S S     G+ K   ++ A++   
Sbjct: 207 EKKAAVRAP--RRG-------PLGGRKKKKAPSASDSDSKADSDGA-KPEPVAMARSASS 256

Query: 284 FSAATKDNEHKRSLTKTP-ARKSAHVTVS---GGTPKGEAVLGTHKLKTITGNSAAGKLK 339
            S+++  ++   S+ K P  RK A   +    G  PK E    +    + + +    ++ 
Sbjct: 257 SSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSS--SDSDSDEVDRIS 314

Query: 340 PWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGLIL 399
            W +  E         R    ++  ++   Q KEE+ ++RE+  + +  +  G   G  L
Sbjct: 315 EWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDEL 374

Query: 400 AED 402
            ED
Sbjct: 375 RED 377


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 56/269 (20%), Positives = 97/269 (36%), Gaps = 42/269 (15%)

Query: 38  ALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAE---------------RQPL 82
           ALK  +   ARK + + D++  S S  + +E    +++ ++               R PL
Sbjct: 161 ALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPL 220

Query: 83  GHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRAT---AKVPSPPDE 139
           G   K +    +   D DS+ +    K   P          S    ++     V  PP  
Sbjct: 221 GGRKKKKAPSAS---DSDSKADSDGAK-PEPVAMARSASSSSSSSSSSDSDVSVKKPPRG 276

Query: 140 HQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESI 199
            + AE  +         P     S  +D  S              +K+  EA  +E+E+ 
Sbjct: 277 RKPAEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDR------ISEWKRRDEARRRELEA- 329

Query: 200 DQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLSVAST---------PISQRR 250
                R+++  EE   + E +++   +   R       R S  S+         P+ +R 
Sbjct: 330 ----RRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPVKKRG 385

Query: 251 SQGRSCGPASQSTLGLKGSLKRSAISAAK 279
            +GR  GP S S    +  L+R A  +AK
Sbjct: 386 RKGRGRGPPSSSDSEPEAELEREAKKSAK 414



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 58/303 (19%), Positives = 109/303 (35%), Gaps = 19/303 (6%)

Query: 105 HSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSL 164
           H+      P    + E  E+     +       D    A  AV++     ++ S+     
Sbjct: 89  HASYSAPPPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDK 148

Query: 165 YTDESSKPGKNKRTAITTPNFKKLHEAHFK-EMESIDQYIERKKKHFEEHNSMNELKQQP 223
            +D S    K K  A+     K+  +A    +  S+    E   +   E    ++    P
Sbjct: 149 SSDNSGL--KRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTP 206

Query: 224 INKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVR 283
             K  VR P   RG       P+  R+ +       S S     G+ K   ++ A++   
Sbjct: 207 EKKAAVRAP--RRG-------PLGGRKKKKAPSASDSDSKADSDGA-KPEPVAMARSASS 256

Query: 284 FSAATKDNEHKRSLTKTP-ARKSAHVTVS---GGTPKGEAVLGTHKLKTITGNSAAGKLK 339
            S+++  ++   S+ K P  RK A   +    G  PK E    +    + + +    ++ 
Sbjct: 257 SSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSS--SDSDSDEVDRIS 314

Query: 340 PWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGLIL 399
            W +  E         R    ++  ++   Q KEE+ ++RE+  + +  +  G   G  L
Sbjct: 315 EWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDEL 374

Query: 400 AED 402
            ED
Sbjct: 375 RED 377


>gi|58530840 desmoplakin isoform I [Homo sapiens]
          Length = 2871

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 45/204 (22%), Positives = 87/204 (42%), Gaps = 23/204 (11%)

Query: 34   KLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCK 93
            K ++ LK   + EA++  E ++E     ++ DE  I + NQ E E     ++TKT     
Sbjct: 1325 KEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEI----NITKTTIHQL 1380

Query: 94   TVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRAT--------AKVPSPPDEHQEAEN 145
            T++ + D+    ++  I N T       +E + L+ T         +V     + +   +
Sbjct: 1381 TMQKEEDTSGYRAQ--IDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGS 1438

Query: 146  AVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIER 205
             VS   +  +V       + T+ES +  ++   A  T   K       KE+E + Q I++
Sbjct: 1439 EVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKN------KEIERLKQLIDK 1492

Query: 206  K---KKHFEEHNSMNELKQQPINK 226
            +   +K  E+ N+  +  Q  + K
Sbjct: 1493 ETNDRKCLEDENARLQRVQYDLQK 1516


>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 1153

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 36/190 (18%), Positives = 78/190 (41%), Gaps = 14/190 (7%)

Query: 76  EAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPS 135
           E ER+    + K +RR K    +   ++ HS +    PTE         Q    T ++P 
Sbjct: 728 EEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSL----PTESDEDIAPAQQVDIVTEEMP- 782

Query: 136 PPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKE 195
                   ENA+ S + D K P++  ++L  D       +++  I      +  ++  K+
Sbjct: 783 --------ENALPS-DEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKD 833

Query: 196 MESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRS 255
           +  +++  ++ KK  ++H      K++   K   ++P P + +        ++ + + + 
Sbjct: 834 VPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKK 893

Query: 256 CGPASQSTLG 265
             P S+   G
Sbjct: 894 QPPGSEEAAG 903


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.123    0.337 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,613,346
Number of Sequences: 37866
Number of extensions: 741672
Number of successful extensions: 5214
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 234
Number of HSP's that attempted gapping in prelim test: 4700
Number of HSP's gapped (non-prelim): 760
length of query: 402
length of database: 18,247,518
effective HSP length: 105
effective length of query: 297
effective length of database: 14,271,588
effective search space: 4238661636
effective search space used: 4238661636
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.