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Search of human proteins with 193804865
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|193804865 nucleolar and spindle associated protein 1 isoform
1 [Homo sapiens]
(441 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|193804865 nucleolar and spindle associated protein 1 isoform ... 877 0.0
gi|17505234 nucleolar and spindle associated protein 1 isoform 2... 870 0.0
gi|193804867 nucleolar and spindle associated protein 1 isoform ... 780 0.0
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 45 1e-04
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 43 7e-04
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 42 9e-04
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 42 9e-04
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 42 9e-04
gi|87162461 fragile X mental retardation 2 [Homo sapiens] 42 0.001
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 40 0.003
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 40 0.003
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 40 0.003
gi|125656165 THO complex 2 [Homo sapiens] 40 0.004
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 40 0.004
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 40 0.004
gi|62244004 modulator of estrogen induced transcription isoform ... 40 0.006
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 39 0.007
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 39 0.012
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 37 0.027
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 37 0.036
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 37 0.036
gi|104526627 triadin [Homo sapiens] 37 0.036
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 37 0.047
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 37 0.047
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 36 0.061
gi|60097902 filaggrin [Homo sapiens] 36 0.061
gi|39995093 parathyroid hormone-like hormone isoform 1 prepropro... 36 0.061
gi|39995091 parathyroid hormone-like hormone isoform 1 prepropro... 36 0.061
gi|39995089 parathyroid hormone-like hormone isoform 2 prepropro... 36 0.061
gi|4506269 parathyroid hormone-like hormone isoform 2 preproprot... 36 0.061
>gi|193804865 nucleolar and spindle associated protein 1 isoform 1
[Homo sapiens]
Length = 441
Score = 877 bits (2265), Expect = 0.0
Identities = 441/441 (100%), Positives = 441/441 (100%)
Query: 1 MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS
Sbjct: 1 MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
Query: 61 ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE
Sbjct: 61 ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI
Sbjct: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
Query: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS 240
TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS
Sbjct: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS 240
Query: 241 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 300
VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT
Sbjct: 241 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 300
Query: 301 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDL 360
PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDL
Sbjct: 301 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDL 360
Query: 361 KASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 420
KASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ
Sbjct: 361 KASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 420
Query: 421 ERKEKKAKVLGMRRGLILAED 441
ERKEKKAKVLGMRRGLILAED
Sbjct: 421 ERKEKKAKVLGMRRGLILAED 441
>gi|17505234 nucleolar and spindle associated protein 1 isoform 2
[Homo sapiens]
Length = 440
Score = 870 bits (2248), Expect = 0.0
Identities = 440/441 (99%), Positives = 440/441 (99%), Gaps = 1/441 (0%)
Query: 1 MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS
Sbjct: 1 MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
Query: 61 ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE
Sbjct: 61 ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI
Sbjct: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
Query: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS 240
TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELK QPINKGGVRTPVPPRGRLS
Sbjct: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELK-QPINKGGVRTPVPPRGRLS 239
Query: 241 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 300
VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT
Sbjct: 240 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 299
Query: 301 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDL 360
PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDL
Sbjct: 300 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDL 359
Query: 361 KASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 420
KASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ
Sbjct: 360 KASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 419
Query: 421 ERKEKKAKVLGMRRGLILAED 441
ERKEKKAKVLGMRRGLILAED
Sbjct: 420 ERKEKKAKVLGMRRGLILAED 440
>gi|193804867 nucleolar and spindle associated protein 1 isoform 3
[Homo sapiens]
Length = 402
Score = 780 bits (2013), Expect = 0.0
Identities = 402/441 (91%), Positives = 402/441 (91%), Gaps = 39/441 (8%)
Query: 1 MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS
Sbjct: 1 MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
Query: 61 ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE
Sbjct: 61 ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI
Sbjct: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
Query: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS 240
TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS
Sbjct: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS 240
Query: 241 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 300
VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT
Sbjct: 241 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 300
Query: 301 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDL 360
PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAA
Sbjct: 301 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAA------------------------- 335
Query: 361 KASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 420
GKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ
Sbjct: 336 --------------GKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 381
Query: 421 ERKEKKAKVLGMRRGLILAED 441
ERKEKKAKVLGMRRGLILAED
Sbjct: 382 ERKEKKAKVLGMRRGLILAED 402
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 45.1 bits (105), Expect = 1e-04
Identities = 86/400 (21%), Positives = 147/400 (36%), Gaps = 37/400 (9%)
Query: 33 TKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRC 92
T ++ G I E K E +++ S ++ E + + EAER L + R R
Sbjct: 223 TVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLE--AEERERI 280
Query: 93 KTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDL-RATAKVPSPPDEHQEAENAVSSGN 151
K + D + I+ Q E++E+++ R + +E Q +
Sbjct: 281 KAEQ-DKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAA 339
Query: 152 RDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFK-EMESIDQYIERKKKHF 210
+ + E +K + + KR A + E K E + ++ +E KK
Sbjct: 340 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAM 399
Query: 211 EEHNSMNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSL 270
+E E +Q I V +L A + QG G Q+ + L
Sbjct: 400 QETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVL-----KKQGEEKGTKVQAK---REKL 451
Query: 271 KRSAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLK--- 327
+ + K ++ KD E K + RK V + GE + THKLK
Sbjct: 452 QEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK--SQNGEFM--THKLKHTE 507
Query: 328 ---TITGNSAAVITPFKLTTEATQTP-VSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQS 383
+ G A+V T EA P V K + +L+ + E K K K +
Sbjct: 508 NTFSRPGGRASVDTK-----EAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAA 562
Query: 384 KENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERK 423
E L + K+ ++ L+ +E++RK+ E +RK
Sbjct: 563 LELEELKK--------KREERRKVLEEEEQRRKQEEADRK 594
Score = 29.6 bits (65), Expect = 5.7
Identities = 37/163 (22%), Positives = 64/163 (39%), Gaps = 23/163 (14%)
Query: 44 KHEARKGNENQDESQTSASSCD----ETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDP 99
K E R+ ++E + D E E + +EE ER+ + R++ +
Sbjct: 571 KREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR-AEAAEKRQKMPEDGLSD 629
Query: 100 DSQQ------NHSEIKISNPTEFQNHEKQESQDLRAT--AKVPSPPDEHQEAENAVSSGN 151
D + S +KI EF N Q+S +++T A + S D E + G
Sbjct: 630 DKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGT 689
Query: 152 RDSK----------VPSEGKKSLYTDESSKPGKNKRTAITTPN 184
+ +K VP+EG +++ + + TA TPN
Sbjct: 690 KSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPN 732
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 42.7 bits (99), Expect = 7e-04
Identities = 52/207 (25%), Positives = 86/207 (41%), Gaps = 21/207 (10%)
Query: 95 VRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDS 154
VR PD +Q H ++ S P + H+ + RA A+ P E+ N + N S
Sbjct: 1230 VRAGPDRRQ-HPSLESSYPPDL--HKSSPHGEKRAHARDPKGSREYSRQPNEHHTWNGTS 1286
Query: 155 KVPSEG--KKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEE 212
+ P G + E + + +R A ++ E + S D +ER++KH E+
Sbjct: 1287 RKPDSGACRPKDRAPEGRRDAQAERAAAANGPKRRSPEKRREGTRSADNTLERREKH-EK 1345
Query: 213 HNSMNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKR 272
++ +++ + R P R R S+ + QRRS R G GS +R
Sbjct: 1346 RRDVSPERRRERSPTRRRDGSPSRRRRSLERL-LEQRRSPERRRG----------GSPER 1394
Query: 273 SAISAAKTGVRFSAATKDNEHKRSLTK 299
AK+ R A + + +RSL K
Sbjct: 1395 ----RAKSTDRRRARSPERRRERSLDK 1417
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 42.4 bits (98), Expect = 9e-04
Identities = 86/423 (20%), Positives = 159/423 (37%), Gaps = 44/423 (10%)
Query: 29 NLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETE----IQISNQEEAERQPLGH 84
+L K+ + +G + E++++ S + D+T+ + +N + P+
Sbjct: 249 SLEQEKVDEEEEGKKDESSCSSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAPVAV 308
Query: 85 VTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEK--------QESQDLRATAKVPSP 136
T T + P + + KIS E + E +++ A A++ +
Sbjct: 309 TTPTVSSGQATPTSPIKKFPTTATKISPKEEERKDESPATWRLGLRKTGSYGALAEITAS 368
Query: 137 PDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKK--LHEAHFK 194
+ +E + A + + S S SL E K K R A P + + +
Sbjct: 369 KEGQKEKDTAGVTRSASSPRLSS---SLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIE 425
Query: 195 EMESIDQYIERKKKHFEEHNSMNELKQQP-INKGGVRTPVPPRGRLS--VASTPISQRRS 251
E E+ D R + ++LK+ +N+G GR + S+ + S
Sbjct: 426 EKENRDSSSLRTSSSYTRRKWEDDLKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPSTTS 485
Query: 252 QGRSCGPASQSTLGLKGSLKRSAISAAK-TGVRFSAATKDNEHKRSLTKTPARKSAHVTV 310
P S GL+ SL S + K T SA T+ + R + K
Sbjct: 486 T-----PTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVP 540
Query: 311 SGGT-PKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLN 369
+ T P V+ N+AA T TT T VS+ V + + S P+
Sbjct: 541 TAVTIPVAPTVV----------NAAASTTTLTTTTAGT---VSSTTEVRERRRSYLTPVR 587
Query: 370 YEPHKGKLKPWG-QSKENNYLNQHVNRINFY---KKTYKQPHLQTKEEQRKKREQERKEK 425
E + + K Q++++ Q V + K + +T+E++ +++E+E KEK
Sbjct: 588 DEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEK 647
Query: 426 KAK 428
+ K
Sbjct: 648 QDK 650
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 42.4 bits (98), Expect = 9e-04
Identities = 86/423 (20%), Positives = 159/423 (37%), Gaps = 44/423 (10%)
Query: 29 NLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETE----IQISNQEEAERQPLGH 84
+L K+ + +G + E++++ S + D+T+ + +N + P+
Sbjct: 336 SLEQEKVDEEEEGKKDESSCSSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAPVAV 395
Query: 85 VTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEK--------QESQDLRATAKVPSP 136
T T + P + + KIS E + E +++ A A++ +
Sbjct: 396 TTPTVSSGQATPTSPIKKFPTTATKISPKEEERKDESPATWRLGLRKTGSYGALAEITAS 455
Query: 137 PDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKK--LHEAHFK 194
+ +E + A + + S S SL E K K R A P + + +
Sbjct: 456 KEGQKEKDTAGVTRSASSPRLSS---SLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIE 512
Query: 195 EMESIDQYIERKKKHFEEHNSMNELKQQP-INKGGVRTPVPPRGRLS--VASTPISQRRS 251
E E+ D R + ++LK+ +N+G GR + S+ + S
Sbjct: 513 EKENRDSSSLRTSSSYTRRKWEDDLKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPSTTS 572
Query: 252 QGRSCGPASQSTLGLKGSLKRSAISAAK-TGVRFSAATKDNEHKRSLTKTPARKSAHVTV 310
P S GL+ SL S + K T SA T+ + R + K
Sbjct: 573 T-----PTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVP 627
Query: 311 SGGT-PKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLN 369
+ T P V+ N+AA T TT T VS+ V + + S P+
Sbjct: 628 TAVTIPVAPTVV----------NAAASTTTLTTTTAGT---VSSTTEVRERRRSYLTPVR 674
Query: 370 YEPHKGKLKPWG-QSKENNYLNQHVNRINFY---KKTYKQPHLQTKEEQRKKREQERKEK 425
E + + K Q++++ Q V + K + +T+E++ +++E+E KEK
Sbjct: 675 DEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEK 734
Query: 426 KAK 428
+ K
Sbjct: 735 QDK 737
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 42.4 bits (98), Expect = 9e-04
Identities = 86/423 (20%), Positives = 159/423 (37%), Gaps = 44/423 (10%)
Query: 29 NLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETE----IQISNQEEAERQPLGH 84
+L K+ + +G + E++++ S + D+T+ + +N + P+
Sbjct: 336 SLEQEKVDEEEEGKKDESSCSSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAPVAV 395
Query: 85 VTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEK--------QESQDLRATAKVPSP 136
T T + P + + KIS E + E +++ A A++ +
Sbjct: 396 TTPTVSSGQATPTSPIKKFPTTATKISPKEEERKDESPATWRLGLRKTGSYGALAEITAS 455
Query: 137 PDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKK--LHEAHFK 194
+ +E + A + + S S SL E K K R A P + + +
Sbjct: 456 KEGQKEKDTAGVTRSASSPRLSS---SLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIE 512
Query: 195 EMESIDQYIERKKKHFEEHNSMNELKQQP-INKGGVRTPVPPRGRLS--VASTPISQRRS 251
E E+ D R + ++LK+ +N+G GR + S+ + S
Sbjct: 513 EKENRDSSSLRTSSSYTRRKWEDDLKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPSTTS 572
Query: 252 QGRSCGPASQSTLGLKGSLKRSAISAAK-TGVRFSAATKDNEHKRSLTKTPARKSAHVTV 310
P S GL+ SL S + K T SA T+ + R + K
Sbjct: 573 T-----PTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVP 627
Query: 311 SGGT-PKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLN 369
+ T P V+ N+AA T TT T VS+ V + + S P+
Sbjct: 628 TAVTIPVAPTVV----------NAAASTTTLTTTTAGT---VSSTTEVRERRRSYLTPVR 674
Query: 370 YEPHKGKLKPWG-QSKENNYLNQHVNRINFY---KKTYKQPHLQTKEEQRKKREQERKEK 425
E + + K Q++++ Q V + K + +T+E++ +++E+E KEK
Sbjct: 675 DEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEK 734
Query: 426 KAK 428
+ K
Sbjct: 735 QDK 737
>gi|87162461 fragile X mental retardation 2 [Homo sapiens]
Length = 1311
Score = 41.6 bits (96), Expect = 0.001
Identities = 84/399 (21%), Positives = 143/399 (35%), Gaps = 46/399 (11%)
Query: 46 EARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNH 105
+A G+ + ES++S+ S +TE ++ E E R T +P S
Sbjct: 479 QASGGSGSSSESESSSESDSDTESSTTDSESNEAP----------RVATPEPEPPSTNKW 528
Query: 106 SEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLY 165
K N QN Q+ + PP Q E + S+VP+E K+
Sbjct: 529 QLDKWLNKVTSQNKSFICGQNETPMETISLPPPIIQPMEVQMKVKTNASQVPAEPKERPL 588
Query: 166 TD---ESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKK--KHFEEHNSMNEL- 219
E ++P R P K L E++ Q KK K E++ S +E
Sbjct: 589 LSLIREKARP----RPTQKIPETKALKHKLSTTSETVSQRTIGKKQPKKVEKNTSTDEFT 644
Query: 220 -------KQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKR 272
P K V PPRGR + A+ R + R P + +G K
Sbjct: 645 WPKPNITSSTPKEKESVELHDPPRGR-NKATAHKPAPRKEPRPNIPLAPEKKKYRGPGK- 702
Query: 273 SAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGN 332
+ ++ + ++T D+ + T + +SGG T K K I G
Sbjct: 703 -IVPKSREFIETDSSTSDSNTDQEET-LQIKVLPPCIISGG--------NTAKSKEICGA 752
Query: 333 SAAVITPFKLTTEATQTPVSNKKPVFD----LKASLSRPLNYEPHKGKLKPWGQSKENNY 388
S + T + +SN++P F ++ + PL H+ W + + +
Sbjct: 753 SLTLSTLMSSSGSNNNLSISNEEPTFSPIPVMQTEILSPL--RDHENLKNLWVKI-DLDL 809
Query: 389 LNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKA 427
L++ + + K H +T + +++ EK A
Sbjct: 810 LSRVPGHSSLHAAPAKPDHKETATKPKRQTAVTAVEKPA 848
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 40.4 bits (93), Expect = 0.003
Identities = 60/344 (17%), Positives = 120/344 (34%), Gaps = 46/344 (13%)
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYT-------------- 166
K + +++ K P D+ +++ ++ S D + P +G KS +T
Sbjct: 1127 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP-QGAKSAHTLGPTPSRTETLVEE 1185
Query: 167 -------DESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNEL 219
D+ P ++ + TP + K +D + + +
Sbjct: 1186 TAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQ 1245
Query: 220 KQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGS---------- 269
+ +P G+ +P + +TP R+ + + G STL L+ +
Sbjct: 1246 EAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK-KGAGNPQASTLALQSNITQCLLGQPW 1304
Query: 270 -LKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARK---SAHVTVSGGTPKGEAVLGTHK 325
L + + A+ V ++ + TK +RK S +SG P K
Sbjct: 1305 PLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKK 1364
Query: 326 LKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSKE 385
K G + T+ ++ K D+K KG L G E
Sbjct: 1365 KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG--------KGSLGSQGAKDE 1416
Query: 386 -NNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAK 428
L + + + ++ + + K+ ++K+++E+KEKK K
Sbjct: 1417 PEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1460
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 40.4 bits (93), Expect = 0.003
Identities = 60/344 (17%), Positives = 120/344 (34%), Gaps = 46/344 (13%)
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYT-------------- 166
K + +++ K P D+ +++ ++ S D + P +G KS +T
Sbjct: 1050 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP-QGAKSAHTLGPTPSRTETLVEE 1108
Query: 167 -------DESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNEL 219
D+ P ++ + TP + K +D + + +
Sbjct: 1109 TAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQ 1168
Query: 220 KQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGS---------- 269
+ +P G+ +P + +TP R+ + + G STL L+ +
Sbjct: 1169 EAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK-KGAGNPQASTLALQSNITQCLLGQPW 1227
Query: 270 -LKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARK---SAHVTVSGGTPKGEAVLGTHK 325
L + + A+ V ++ + TK +RK S +SG P K
Sbjct: 1228 PLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKK 1287
Query: 326 LKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSKE 385
K G + T+ ++ K D+K KG L G E
Sbjct: 1288 KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG--------KGSLGSQGAKDE 1339
Query: 386 -NNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAK 428
L + + + ++ + + K+ ++K+++E+KEKK K
Sbjct: 1340 PEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1383
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 40.4 bits (93), Expect = 0.003
Identities = 60/344 (17%), Positives = 120/344 (34%), Gaps = 46/344 (13%)
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYT-------------- 166
K + +++ K P D+ +++ ++ S D + P +G KS +T
Sbjct: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP-QGAKSAHTLGPTPSRTETLVEE 1147
Query: 167 -------DESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNEL 219
D+ P ++ + TP + K +D + + +
Sbjct: 1148 TAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQ 1207
Query: 220 KQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGS---------- 269
+ +P G+ +P + +TP R+ + + G STL L+ +
Sbjct: 1208 EAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK-KGAGNPQASTLALQSNITQCLLGQPW 1266
Query: 270 -LKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARK---SAHVTVSGGTPKGEAVLGTHK 325
L + + A+ V ++ + TK +RK S +SG P K
Sbjct: 1267 PLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKK 1326
Query: 326 LKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSKE 385
K G + T+ ++ K D+K KG L G E
Sbjct: 1327 KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG--------KGSLGSQGAKDE 1378
Query: 386 -NNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAK 428
L + + + ++ + + K+ ++K+++E+KEKK K
Sbjct: 1379 PEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1422
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 40.0 bits (92), Expect = 0.004
Identities = 79/399 (19%), Positives = 148/399 (37%), Gaps = 41/399 (10%)
Query: 50 GNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIK 109
G S SAS DE+ + +++ ER G K + + +S +S
Sbjct: 1205 GGGPSSSSIGSASKSDESSTEETDKSR-ERSQCG--VKAVNKASSTTPKGNSSNGNSGSN 1261
Query: 110 ISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDES 169
+ + + EK + ++ K P+ E + + +GK+ +
Sbjct: 1262 SNKAVKENDKEKGKEKEKEKKEKTPATTPEARV-------------LGKDGKEKPKEERP 1308
Query: 170 SKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYI---------------ERKKKHFEEHN 214
+K K + T TP K E KE ++ D+ ER+K+ E +
Sbjct: 1309 NKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERD 1368
Query: 215 SMNELKQQPINKGGVRTPVPPRGRLSVASTPISQ-RRSQGR---SCGPASQSTLGLKGSL 270
E+K + KGG +TPV + V + I + R Q R P+ + +K SL
Sbjct: 1369 IAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSSTVKDSL 1428
Query: 271 KRSAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTIT 330
S+AK + + +R + K KS S K + + + +
Sbjct: 1429 IELKESSAKLYINHTPPPLSKSKEREMDKKDLDKSRE--RSREREKKDEKDRKERKRDHS 1486
Query: 331 GNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSK-ENNYL 389
N V + + K + P + K K K G+ K +++
Sbjct: 1487 NNDREVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSFK 1546
Query: 390 NQHVNRINFYKKTYKQPHLQTKEEQRKKREQE--RKEKK 426
++ +++I+ K + H + K E+++KR+ ++EKK
Sbjct: 1547 SEKMDKISSGGKK-ESRHDKEKIEKKEKRDSSGGKEEKK 1584
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 40.0 bits (92), Expect = 0.004
Identities = 60/345 (17%), Positives = 120/345 (34%), Gaps = 47/345 (13%)
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYT-------------- 166
K + +++ K P D+ +++ ++ S D + P +G KS +T
Sbjct: 1050 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP-QGAKSAHTLVGPTPSRTETLVE 1108
Query: 167 --------DESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNE 218
D+ P ++ + TP + K +D + + +
Sbjct: 1109 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1168
Query: 219 LKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGS--------- 269
+ +P G+ +P + +TP R+ + + G STL L+ +
Sbjct: 1169 QEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK-KGAGNPQASTLALQSNITQCLLGQP 1227
Query: 270 --LKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARK---SAHVTVSGGTPKGEAVLGTH 324
L + + A+ V ++ + TK +RK S +SG P
Sbjct: 1228 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1287
Query: 325 KLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSK 384
K K G + T+ ++ K D+K KG L G
Sbjct: 1288 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG--------KGSLGSQGAKD 1339
Query: 385 E-NNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAK 428
E L + + + ++ + + K+ ++K+++E+KEKK K
Sbjct: 1340 EPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1384
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 40.0 bits (92), Expect = 0.004
Identities = 60/345 (17%), Positives = 120/345 (34%), Gaps = 47/345 (13%)
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYT-------------- 166
K + +++ K P D+ +++ ++ S D + P +G KS +T
Sbjct: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP-QGAKSAHTLVGPTPSRTETLVE 1147
Query: 167 --------DESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNE 218
D+ P ++ + TP + K +D + + +
Sbjct: 1148 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1207
Query: 219 LKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGS--------- 269
+ +P G+ +P + +TP R+ + + G STL L+ +
Sbjct: 1208 QEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK-KGAGNPQASTLALQSNITQCLLGQP 1266
Query: 270 --LKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARK---SAHVTVSGGTPKGEAVLGTH 324
L + + A+ V ++ + TK +RK S +SG P
Sbjct: 1267 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1326
Query: 325 KLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSK 384
K K G + T+ ++ K D+K KG L G
Sbjct: 1327 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG--------KGSLGSQGAKD 1378
Query: 385 E-NNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAK 428
E L + + + ++ + + K+ ++K+++E+KEKK K
Sbjct: 1379 EPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1423
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 39.7 bits (91), Expect = 0.006
Identities = 71/330 (21%), Positives = 124/330 (37%), Gaps = 38/330 (11%)
Query: 117 QNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDS---KVPSEGKKSLYTDESSKPG 173
Q+ E++E++ + A+ E EA V D+ + +E +L D
Sbjct: 187 QDGEEEENEKEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLE 246
Query: 174 KNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPV 233
K IT K + ++I Q E++ K +E + + + K++ KG PV
Sbjct: 247 TGKNVKITDSEASKPKDGQ----DAIAQSPEKESKDYEMNANHKDGKKEDCVKGD---PV 299
Query: 234 PPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEH 293
R S + GP+S G A S++K ++KD++
Sbjct: 300 EKEARESSKKAESGDKEKDTLKKGPSSTGASG-------QAKSSSKESKDSKTSSKDDKG 352
Query: 294 KRSLTKTPARKSA-HVTVSGGTPKGEAVLGTHKLKTITGN-----SAAVITP-------- 339
S T + S ++ VSG + +A LK + G SA V+T
Sbjct: 353 STSSTSGSSGSSTKNIWVSGLSSNTKAA----DLKNLFGKYGKVLSAKVVTNARSPGAKC 408
Query: 340 FKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVN---RI 396
+ + T ++ T VS + ++ E KG KEN+ + + +
Sbjct: 409 YGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKK 468
Query: 397 NFYKKTYKQPHLQTKEEQRKKREQERKEKK 426
N ++ K KEE+R + E+KE K
Sbjct: 469 NTSDRSSKTQASVKKEEKRSSEKSEKKESK 498
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 39.3 bits (90), Expect = 0.007
Identities = 46/215 (21%), Positives = 85/215 (39%), Gaps = 23/215 (10%)
Query: 59 TSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQN 118
T + +E + S+ EE + + + TK + K P Q S+ ++ +
Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSS 477
Query: 119 HEKQESQDLRATAK----------VPSPPDEHQE--AENAVSSGNRDSKVPSEGK-KSLY 165
E++E + ++ K PS P ++ AE++ SS + DS E K K
Sbjct: 478 SEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKG 537
Query: 166 TDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPIN 225
+ P N +A+T N K + +E E KKK + LK++ N
Sbjct: 538 SPRPQAPKANGTSALTAQNGKAAKNSEEEE--------EEKKKAAVVVSKSGSLKKRKQN 589
Query: 226 KGG--VRTPVPPRGRLSVASTPISQRRSQGRSCGP 258
+ TP + +L +T +++ + R+ P
Sbjct: 590 EAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSP 624
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 38.5 bits (88), Expect = 0.012
Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 28/191 (14%)
Query: 49 KGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNH-SE 107
+ ++ +DE + E E S++E+ +P D DS+ N S
Sbjct: 44 RASDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQ-------------DQDSEVNELSR 90
Query: 108 IKISNPTEFQNHEKQESQ--DLRATAK-VPSPPDEHQEAENAVSSGNRDSKVPSEGKKSL 164
S+P E + E +E + DLR A V DEH+ + D +VP E ++
Sbjct: 91 GPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHEL--------DYDEEVPEEPAPAV 142
Query: 165 YTDESSKPGK--NKRTAITTPNFK-KLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQ 221
DE+ K G ++ TP + K E ES++ E+KK+ + E+
Sbjct: 143 QEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDD 202
Query: 222 QPINKGGVRTP 232
+ +G V+ P
Sbjct: 203 DDLEEGEVKDP 213
Score = 35.4 bits (80), Expect = 0.10
Identities = 78/423 (18%), Positives = 141/423 (33%), Gaps = 53/423 (12%)
Query: 44 KHEARKGNENQDES-QTSASSCDETEIQISNQE-EAERQPLGHVTKTRRRCKTVRVDPDS 101
+HE K + + E + + DE + Q +++ E ER+ K + + K P S
Sbjct: 439 EHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKERE------KEKGKPKPRSPQPPS 492
Query: 102 QQNHSEIKISNPTEFQNHEKQESQDLRATAKVP--------SPPDEHQEAENAVSSGNRD 153
+Q K + T Q E +D +K P SP + + + SS +
Sbjct: 493 RQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASAS 552
Query: 154 SKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHF--- 210
+ S + S Y+ S +++ ++ ++ + + + F S +
Sbjct: 553 NSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTP 612
Query: 211 EEHNSMNELKQQPINKGG------VRTPVPPRGRLSVAST------------PISQRRSQ 252
H K +P G V+ P PP T P RR +
Sbjct: 613 SPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKE 672
Query: 253 GRSCGPASQSTLGLKGSLKRSAISAAKTGVR---------FSAATKDNEHKRSLTKTPAR 303
+ P + TL GS S+ S + + R S+AT + S+
Sbjct: 673 RPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMY 732
Query: 304 KSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKAS 363
VS + + A T K K + V + +TQ P S K P
Sbjct: 733 ADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPA------ 786
Query: 364 LSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERK 423
+ +P + P GQ ++ ++ ++ K + + E K R+
Sbjct: 787 -GGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPP 845
Query: 424 EKK 426
K+
Sbjct: 846 AKR 848
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 37.4 bits (85), Expect = 0.027
Identities = 30/146 (20%), Positives = 54/146 (36%), Gaps = 9/146 (6%)
Query: 34 KLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCK 93
+L ++KG IK +A + + + DE + SN + + R++C
Sbjct: 999 RLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDED-----EQRKKCA 1053
Query: 94 TVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRD 153
+ D D QN S + +P + + D ++ P Q +V SG
Sbjct: 1054 SSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSH 1113
Query: 154 SKVPSEGKK----SLYTDESSKPGKN 175
S V + S +D S+ G +
Sbjct: 1114 SGVSENDSRPASPSAESDHESERGSD 1139
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 37.0 bits (84), Expect = 0.036
Identities = 72/337 (21%), Positives = 116/337 (34%), Gaps = 55/337 (16%)
Query: 42 YIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPD- 100
Y+ H R E +E Q +E +++ E A R+ +TK +R T DP+
Sbjct: 33 YLAHSGRSHLE-PEEKQALKRLVEEELLKMQVDEAASREDKLDLTKKGKRPPTPCSDPER 91
Query: 101 -----SQQNHSEIKISNPTEFQNHEK----------QESQDLRATAKVPSPPDEHQEAEN 145
+ ++ S + S+P F K +E RA+ V DE ++ +
Sbjct: 92 KRFRFNSESESGSEASSPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEESSDEERQRDL 151
Query: 146 AVSSGNRDSKVPSEG-----------------------KKSLYTDESSKPGKNKRTAITT 182
G S+ +G K++ E S+ +RTA
Sbjct: 152 PAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSRKQAREESEESEAEPVQRTAKKV 211
Query: 183 PNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLSVA 242
K E ES ++ + +KK+ EE E K++ KG + GR A
Sbjct: 212 EGNKGTKSLKESEQESEEEILAQKKEQREEEVEEEE-KEEDEEKGDWKPRTRSNGRRKSA 270
Query: 243 STPISQRRSQGRSCGPASQSTLGLKGS-----LKRSAISAAKTGVRFSAATKDNEHKRSL 297
+ RSC SQ+ L S K +A S +G + R+
Sbjct: 271 --------REERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDRTQ 322
Query: 298 TKTPARKSAHVTVSGGTPKGE-AVLGTHKLKTITGNS 333
K R S + KGE G+ K+ + S
Sbjct: 323 LKGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGSTS 359
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 37.0 bits (84), Expect = 0.036
Identities = 37/171 (21%), Positives = 75/171 (43%), Gaps = 12/171 (7%)
Query: 55 DESQTSASSCDETEI--QISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKIS- 111
DE+ S TE+ ++ + E+A+ +P G R+ C+ + S H ++I
Sbjct: 459 DEATKCISHLHRTELHGRMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKI 518
Query: 112 NPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSK 171
T + EK E ++ + + + E + ++ +R +K S G + + SK
Sbjct: 519 EKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSK 578
Query: 172 PGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQ 222
G+ + TT K+ + +S D+ E K+K + S +++K+Q
Sbjct: 579 -GEPVISVKTTSRSKE------RSSKSQDRKSESKEK--RDILSFDKIKEQ 620
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 37.0 bits (84), Expect = 0.036
Identities = 86/398 (21%), Positives = 156/398 (39%), Gaps = 46/398 (11%)
Query: 46 EARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNH 105
E KG E E + E +I +E+ E + L K +++ KT + ++
Sbjct: 166 EKEKGKEKVREKEKPEKKATHKE-KIEKKEKPETKTLA---KEQKKAKTA--EKSEEKTK 219
Query: 106 SEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGN--RDSKVPSEGKKS 163
E+K Q KQ + ++ K PS P E ++ E A S + +D
Sbjct: 220 KEVKGGK----QEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMID 275
Query: 164 LYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQP 223
++ KPG++ AI P + ++++ KKK ++ S + K++
Sbjct: 276 IFVHGDLKPGQS--PAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKE 333
Query: 224 INKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVR 283
K + S T I + + G AS++ +G++K +A +AAK +
Sbjct: 334 DIK-----------KKSEKETAIDVEKKEP---GKASETK---QGTVKIAAQAAAKKDEK 376
Query: 284 FSAATKDN---EHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVI--- 337
+ K E ++ K +K HV + K +V ++K T + I
Sbjct: 377 KEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAV 436
Query: 338 -----TPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQS-KENNYLNQ 391
P K + T+T + K S S + EP KGK + S KE +
Sbjct: 437 SIKKAVPGKKEEKTTKTVEQEIRKEKSGKTS-SILKDKEPIKGKEEKVPASLKEKEPETK 495
Query: 392 HVNRINFYKKTY--KQPHLQTKEEQRKKREQERKEKKA 427
+++ K K P LQ K+E++ + + +++ K A
Sbjct: 496 KDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPA 533
Score = 30.4 bits (67), Expect = 3.3
Identities = 47/244 (19%), Positives = 84/244 (34%), Gaps = 23/244 (9%)
Query: 83 GHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEK-------QESQDLRATAKVPS 135
G + + R K + D +Q E KI + EK +E + +AT K
Sbjct: 131 GEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKI 190
Query: 136 PPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKE 195
E E + K + K T + K GK ++ T K++ + K
Sbjct: 191 EKKEKPETKTLAKE---QKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKP 247
Query: 196 MESIDQYIERKKKHFEEH-----NSMNELKQQPINKGGVRTPVPP------RGRLSVAST 244
E D+ KH ++ M ++ K G +PP R + AS
Sbjct: 248 KEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASP 307
Query: 245 PISQRRSQGRSCGP--ASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTPA 302
+ ++ + + S++ K +K+ + V K +E K+ K A
Sbjct: 308 ALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAA 367
Query: 303 RKSA 306
+ +A
Sbjct: 368 QAAA 371
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 36.6 bits (83), Expect = 0.047
Identities = 38/166 (22%), Positives = 70/166 (42%), Gaps = 23/166 (13%)
Query: 30 LRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQP-------L 82
+RA + LK + + E + ++ ++E E I +EE E P +
Sbjct: 261 VRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMM 320
Query: 83 GHVTKTRRRCKTV--------RVDPDSQQNH-------SEIKISNPTEFQNHEKQESQDL 127
KTR + + V R +++++H E+K ++P E + E + SQ L
Sbjct: 321 DERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGL 380
Query: 128 RATAKVPSPPDEHQEAENA-VSSGNRDSKVPSEGKKSLYTDESSKP 172
+ +K PSPP ++ + A + + + E L T E+S P
Sbjct: 381 KEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSP 426
Score = 32.7 bits (73), Expect = 0.67
Identities = 68/344 (19%), Positives = 121/344 (35%), Gaps = 77/344 (22%)
Query: 7 EELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDE 66
+E S S +Q S A T+ L+ +G + K E ++ +A+
Sbjct: 694 KERTSTSSSSVQARRLSQPESAEKHVTQRLQPERG-----SPKKCEAEEAEPPAATQPQT 748
Query: 67 TEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPT-----EFQNHEK 121
+E Q S+ E+ER + H + + V D+ +N E + P + N ++
Sbjct: 749 SETQTSHLPESER--IHHTVEEKEE-----VTMDTSENRPENDVPEPPMPIADQVSNDDR 801
Query: 122 QESQDLRATAKVPSPPDEHQE------AENAVSSGNRDSKVPSEGKKSLYTDESSKPGKN 175
E K S P + A V +GN D++ G+K + ++ K
Sbjct: 802 PEGSVEDEEKKESSLPKSFKRKISVVSATKGVPAGNSDTEGGQPGRKRRWGASTATTQKK 861
Query: 176 KRTAITTPNFKKL------------------------------------HEAHFKEMESI 199
+ITT + K L H+ K ++
Sbjct: 862 PSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTV 921
Query: 200 DQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPA 259
Q + + + + E K+ PVPP+ + VA P ++
Sbjct: 922 TQVVPAEGQENGQREEEEEEKEPE-----AEPPVPPQVSVEVALPPPAEHE--------V 968
Query: 260 SQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTPAR 303
+ TLG +L R +IS K+GV + T D+ + + +P R
Sbjct: 969 KKVTLG--DTLTRRSISQQKSGV---SITIDDPVRTAQVPSPPR 1007
Score = 30.8 bits (68), Expect = 2.6
Identities = 45/223 (20%), Positives = 91/223 (40%), Gaps = 27/223 (12%)
Query: 9 LDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNEN-----QDESQTSASS 63
L +L+ +DL+ + GL + + + L+K LKG + E + + Q SQ
Sbjct: 72 LQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQPNSQIGEEM 131
Query: 64 CDETEIQ--ISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSE-IKISNPTEFQNH- 119
+ I+ + Q+E RQ L + + + + + H E + P +FQ+
Sbjct: 132 SQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASLLPPDFQSSL 191
Query: 120 EKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGK---------KSLYTDESS 170
E+ E + R + + S E + G+ D + P +G+ ++ E S
Sbjct: 192 ERPELELSRHSPRKSSSISEEK--------GDSDDEKPRKGERRSSRVRQARAAKLSEGS 243
Query: 171 KPGKNKRTAIT-TPNFKKLHEAHFKEMESIDQYIERKKKHFEE 212
+P + + T + N + + + K E ++ E ++ EE
Sbjct: 244 QPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEE 286
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 36.6 bits (83), Expect = 0.047
Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 27/202 (13%)
Query: 32 ATKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEE------------AER 79
A K K +K +K + +K + +D T A S D + + +++ ++
Sbjct: 306 AKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKK 365
Query: 80 QPLGHVTKT---------RRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRAT 130
P T++ R K + D +++ +I S +E + K+ +D +
Sbjct: 366 YPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKD 425
Query: 131 AKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHE 190
K S D + +N S + DS+ + KK ++ K K+ + + KK
Sbjct: 426 KK-DSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGK--KDSKKDDKKKDAKK--N 480
Query: 191 AHFKEMESIDQYIERKKKHFEE 212
A EMES D +++ KKH +E
Sbjct: 481 AESTEMES-DLELKKDKKHSKE 501
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 36.2 bits (82), Expect = 0.061
Identities = 52/263 (19%), Positives = 106/263 (40%), Gaps = 30/263 (11%)
Query: 44 KHEARKGNENQDESQTSASSCDETEIQISNQEEA----ERQPLGHVTKTRRRCKTV--RV 97
K ++R + + +S++ + D+ E +I N + R P H +K++ R ++ RV
Sbjct: 252 KEKSRSRSHSAGKSRSKSK--DQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRV 309
Query: 98 DPDSQQNHSEIKISNPTEFQNHEKQESQD---LRATAKVPSPPDEHQEAENAVSSGNRD- 153
+ + + + S + + Q+ + S+ R+ ++ S + S +R
Sbjct: 310 EEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSR 369
Query: 154 SKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEH 213
S+ SE + + SK G +K+ KK + + S + + ++++H +
Sbjct: 370 SRSKSERSRKRGSKRDSKAGSSKK--------KKKEDTDRSQSRSPSRSVSKEREHAKSE 421
Query: 214 NSMNELKQQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRS 273
+S E + + N G R R + S P S+ RS ++ T S RS
Sbjct: 422 SSQREGRGESEN-AGTNQETRSRSRSNSKSKP--NLPSESRSRSKSASKTRSRSKSRSRS 478
Query: 274 AISAAKTGVRFSAATKDNEHKRS 296
A R + ++ H RS
Sbjct: 479 A-------SRSPSRSRSRSHSRS 494
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 36.2 bits (82), Expect = 0.061
Identities = 28/125 (22%), Positives = 53/125 (42%), Gaps = 6/125 (4%)
Query: 56 ESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTE 115
E S+ +++ S E + PL +RR V D DS+ + + + + +
Sbjct: 258 ERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSA 317
Query: 116 FQNHEKQESQDLRATAKVPSPPDEHQ-----EAENAVSSGNRDSKVPSEGK-KSLYTDES 169
+NH + R ++ P DE + A+++ SG R ++ S G+ S +
Sbjct: 318 SRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQAR 377
Query: 170 SKPGK 174
S PG+
Sbjct: 378 SSPGE 382
Score = 32.0 bits (71), Expect = 1.1
Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 7/121 (5%)
Query: 48 RKGNENQDESQTSASSCDE--TEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNH 105
R ++ D S+ S S E T IS +A + ++RR+ +V D DS+ +
Sbjct: 2842 RNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHS 2901
Query: 106 SEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQ-----EAENAVSSGNRDSKVPSEG 160
+ + + + +NH + LR ++ P E + A+++ SG R ++ S G
Sbjct: 2902 EDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGG 2961
Query: 161 K 161
+
Sbjct: 2962 Q 2962
Score = 31.6 bits (70), Expect = 1.5
Identities = 31/135 (22%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Query: 48 RKGNENQDESQTSASSCDE--TEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNH 105
R ++ D S+ S S E T IS +A + ++RR+ +V D DS+ +
Sbjct: 3166 RNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHS 3225
Query: 106 SEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQ-----EAENAVSSGNRDSKVPSEG 160
+ + + + +NH + R ++ P E + A+ + SG R ++ S G
Sbjct: 3226 EDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGG 3285
Query: 161 K-KSLYTDESSKPGK 174
+ S + S PG+
Sbjct: 3286 QAASSHEQARSSPGE 3300
Score = 28.9 bits (63), Expect = 9.7
Identities = 29/138 (21%), Positives = 62/138 (44%), Gaps = 10/138 (7%)
Query: 46 EARKGNENQDESQTSASSCDETEIQISNQEEAE---RQPLGHVTKTRRRCKTVRVDPDSQ 102
+ R ++ D S+ S S E + + ++ + G T +RR+ +V D DS+
Sbjct: 1543 QTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKT-SRRQGSSVSQDRDSE 1601
Query: 103 QNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQ-----EAENAVSSGNRDSKVP 157
+ + + + + +NH + R ++ P E + AE++ SG R ++
Sbjct: 1602 GHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETS 1661
Query: 158 SEGKKSLYTDES-SKPGK 174
S G+ + +++ S PG+
Sbjct: 1662 SGGQAASSQEQARSSPGE 1679
>gi|39995093 parathyroid hormone-like hormone isoform 1
preproprotein [Homo sapiens]
Length = 177
Score = 36.2 bits (82), Expect = 0.061
Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 380 WGQSKENNYLNQHVNRINFYK-KTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGL 436
+G E YL Q N++ YK + K P + K + K++EQE+K+++ + + G+
Sbjct: 95 FGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGV 152
>gi|39995091 parathyroid hormone-like hormone isoform 1
preproprotein [Homo sapiens]
Length = 177
Score = 36.2 bits (82), Expect = 0.061
Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 380 WGQSKENNYLNQHVNRINFYK-KTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGL 436
+G E YL Q N++ YK + K P + K + K++EQE+K+++ + + G+
Sbjct: 95 FGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGV 152
>gi|39995089 parathyroid hormone-like hormone isoform 2
preproprotein [Homo sapiens]
Length = 175
Score = 36.2 bits (82), Expect = 0.061
Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 380 WGQSKENNYLNQHVNRINFYK-KTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGL 436
+G E YL Q N++ YK + K P + K + K++EQE+K+++ + + G+
Sbjct: 95 FGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGV 152
>gi|4506269 parathyroid hormone-like hormone isoform 2 preproprotein
[Homo sapiens]
Length = 175
Score = 36.2 bits (82), Expect = 0.061
Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 380 WGQSKENNYLNQHVNRINFYK-KTYKQPHLQTKEEQRKKREQERKEKKAKVLGMRRGL 436
+G E YL Q N++ YK + K P + K + K++EQE+K+++ + + G+
Sbjct: 95 FGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGV 152
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,048,719
Number of Sequences: 37866
Number of extensions: 806402
Number of successful extensions: 5508
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 252
Number of HSP's that attempted gapping in prelim test: 4911
Number of HSP's gapped (non-prelim): 821
length of query: 441
length of database: 18,247,518
effective HSP length: 105
effective length of query: 336
effective length of database: 14,271,588
effective search space: 4795253568
effective search space used: 4795253568
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.