Guide to the Human Genome
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Search of human proteins with 19263340

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19263340 glutamic pyruvate transaminase 2 isoform 1 [Homo
sapiens]
         (523 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19263340 glutamic pyruvate transaminase 2 isoform 1 [Homo sap...  1054   0.0  
gi|215599424 glutamic pyruvate transaminase 2 isoform 2 [Homo sa...   865   0.0  
gi|4885351 glutamic pyruvate transaminase [Homo sapiens]              706   0.0  
gi|4507369 tyrosine aminotransferase [Homo sapiens]                    82   1e-15
gi|187936925 1-aminocyclopropane-1-carboxylate synthase homolog ...    62   1e-09
gi|14211921 1-aminocyclopropane-1-carboxylate synthase homolog [...    62   1e-09
gi|149944424 1-aminocyclopropane-1-carboxylate synthase homolog ...    55   2e-07
gi|56713254 kynurenine aminotransferase III isoform 1 [Homo sapi...    40   0.005
gi|56713256 kynurenine aminotransferase III isoform 2 [Homo sapi...    40   0.005
gi|169881279 kynurenine aminotransferase I isoform a [Homo sapiens]    38   0.026
gi|95147551 kynurenine aminotransferase I isoform a [Homo sapiens]     38   0.026
gi|169881281 kynurenine aminotransferase I isoform b [Homo sapiens]    35   0.22 
gi|148727286 acyl-CoA thioesterase 2 [Homo sapiens]                    30   4.1  
gi|81230485 acyl-CoA thioesterase 1 [Homo sapiens]                     30   4.1  
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    30   5.4  
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    30   5.4  
gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]     30   7.0  
gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]       30   7.0  
gi|169217528 PREDICTED: similar to sidekick homolog 2 (chicken) ...    29   9.2  

>gi|19263340 glutamic pyruvate transaminase 2 isoform 1 [Homo
           sapiens]
          Length = 523

 Score = 1054 bits (2726), Expect = 0.0
 Identities = 523/523 (100%), Positives = 523/523 (100%)

Query: 1   MQRAAALVRRGCGPRTPSSWGRSQSSAAAEASAVLKVRPERSRRERILTLESMNPQVKAV 60
           MQRAAALVRRGCGPRTPSSWGRSQSSAAAEASAVLKVRPERSRRERILTLESMNPQVKAV
Sbjct: 1   MQRAAALVRRGCGPRTPSSWGRSQSSAAAEASAVLKVRPERSRRERILTLESMNPQVKAV 60

Query: 61  EYAVRGPIVLKAGEIELELQRGIKKPFTEVIRANIGDAQAMGQQPITFLRQVMALCTYPN 120
           EYAVRGPIVLKAGEIELELQRGIKKPFTEVIRANIGDAQAMGQQPITFLRQVMALCTYPN
Sbjct: 61  EYAVRGPIVLKAGEIELELQRGIKKPFTEVIRANIGDAQAMGQQPITFLRQVMALCTYPN 120

Query: 121 LLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDN 180
           LLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDN
Sbjct: 121 LLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDN 180

Query: 181 IYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENC 240
           IYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENC
Sbjct: 181 IYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENC 240

Query: 241 WALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADE 300
           WALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADE
Sbjct: 241 WALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADE 300

Query: 301 VYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLH 360
           VYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLH
Sbjct: 301 VYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLH 360

Query: 361 PEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLT 420
           PEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLT
Sbjct: 361 PEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLT 420

Query: 421 EDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVP 480
           EDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVP
Sbjct: 421 EDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVP 480

Query: 481 GSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLEKYA 523
           GSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLEKYA
Sbjct: 481 GSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLEKYA 523


>gi|215599424 glutamic pyruvate transaminase 2 isoform 2 [Homo
           sapiens]
          Length = 423

 Score =  865 bits (2234), Expect = 0.0
 Identities = 423/423 (100%), Positives = 423/423 (100%)

Query: 101 MGQQPITFLRQVMALCTYPNLLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIR 160
           MGQQPITFLRQVMALCTYPNLLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIR
Sbjct: 1   MGQQPITFLRQVMALCTYPNLLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIR 60

Query: 161 EDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYS 220
           EDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYS
Sbjct: 61  EDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYS 120

Query: 221 AVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRK 280
           AVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRK
Sbjct: 121 AVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRK 180

Query: 281 CIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTS 340
           CIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTS
Sbjct: 181 CIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTS 240

Query: 341 KGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFE 400
           KGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFE
Sbjct: 241 KGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFE 300

Query: 401 QFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQM 460
           QFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQM
Sbjct: 301 QFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQM 360

Query: 461 APDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLE 520
           APDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLE
Sbjct: 361 APDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLE 420

Query: 521 KYA 523
           KYA
Sbjct: 421 KYA 423


>gi|4885351 glutamic pyruvate transaminase [Homo sapiens]
          Length = 496

 Score =  706 bits (1821), Expect = 0.0
 Identities = 331/480 (68%), Positives = 409/480 (85%)

Query: 44  RERILTLESMNPQVKAVEYAVRGPIVLKAGEIELELQRGIKKPFTEVIRANIGDAQAMGQ 103
           R ++LTL+ MNP+V+ VEYAVRGPIV +A E+E EL++G+KKPFTEVIRANIGDAQAMGQ
Sbjct: 17  RAKVLTLDGMNPRVRRVEYAVRGPIVQRALELEQELRQGVKKPFTEVIRANIGDAQAMGQ 76

Query: 104 QPITFLRQVMALCTYPNLLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDV 163
           +PITFLRQV+ALC  P+LL SP+FP+DAKKRA RILQACGG+SLG+YS S G+  IREDV
Sbjct: 77  RPITFLRQVLALCVNPDLLSSPNFPDDAKKRAERILQACGGHSLGAYSVSSGIQLIREDV 136

Query: 164 AAYITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVI 223
           A YI RRDGG+PADP+N++L+TGASD I T+LK+LV+G G +RTGV+IPIPQYPLYSA +
Sbjct: 137 ARYIERRDGGIPADPNNVFLSTGASDAIVTVLKLLVAGEGHTRTGVLIPIPQYPLYSATL 196

Query: 224 SELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIE 283
           +EL A+QV+YYLDEE  WAL+V EL RA+ +A+DHC P+ LC+INPGNPTGQVQ+R+CIE
Sbjct: 197 AELGAVQVDYYLDEERAWALDVAELHRALGQARDHCRPRALCVINPGNPTGQVQTRECIE 256

Query: 284 DVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGY 343
            VI FA+EE+LFLLADEVYQDNVY+   +FHSFKKVL EMGP Y+   ELASFHSTSKGY
Sbjct: 257 AVIRFAFEERLFLLADEVYQDNVYAAGSQFHSFKKVLMEMGPPYAGQQELASFHSTSKGY 316

Query: 344 MGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFS 403
           MGECG+RGGY+EV+N+   ++ Q++KL+SVRLCPPV GQA +D+VV+PP   + SF QF 
Sbjct: 317 MGECGFRGGYVEVVNMDAAVQQQMLKLMSVRLCPPVPGQALLDLVVSPPAPTDPSFAQFQ 376

Query: 404 REKESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPD 463
            EK++VL  LA KAKLTE +FN+ PGI CNP+QGAMY+FPR+ +P +AVE AQ   +APD
Sbjct: 377 AEKQAVLAELAAKAKLTEQVFNEAPGISCNPVQGAMYSFPRVQLPPRAVERAQELGLAPD 436

Query: 464 MFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLEKYA 523
           MF+C++LLEETGICVVPGSGFGQREGTYHFRMTILPP+EKL+ +L+K+  FH  F  +Y+
Sbjct: 437 MFFCLRLLEETGICVVPGSGFGQREGTYHFRMTILPPLEKLRLLLEKLSRFHAKFTLEYS 496


>gi|4507369 tyrosine aminotransferase [Homo sapiens]
          Length = 454

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 90/381 (23%), Positives = 157/381 (41%), Gaps = 50/381 (13%)

Query: 141 ACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVS 200
           A        Y+ S G    RE++A+Y    +   P +  ++ LT+G S  I   L +L +
Sbjct: 100 ALDSGKYNGYAPSIGFLSSREEIASYYHCPEA--PLEAKDVILTSGCSQAIDLCLAVLAN 157

Query: 201 GGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCD 260
            G      +++P P + LY  +   +      Y L  E  W +++ +L   + E      
Sbjct: 158 PG----QNILVPRPGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDE------ 207

Query: 261 PKVLCII--NPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKK 318
            K  C+I  NP NP G V S++ ++ ++  A  + + +LADE+Y D V+S DC+      
Sbjct: 208 -KTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFS-DCK------ 259

Query: 319 VLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHP----EIKGQLVKLLSVR 374
             YE     S++V + S    +K ++   G+R G++ + +       EI+  LVKL    
Sbjct: 260 --YEPLATLSTDVPILSCGGLAKRWLVP-GWRLGWILIHDRRDIFGNEIRDGLVKLSQRI 316

Query: 375 LCPPVSGQAAM-DIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQVPGIHCN 433
           L P    Q A+  I+   P               + L  L   A L       +PG+   
Sbjct: 317 LGPCTIVQGALKSILCRTP----------GEFYHNTLSFLKSNADLCYGALAAIPGLRPV 366

Query: 434 PLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHF 493
              GAMY           +E     +   D+ +  +L+ E  +  +P + F   E     
Sbjct: 367 RPSGAMYLM-------VGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCF---EYPNFI 416

Query: 494 RMTILPPVEKLKTVLQKVKDF 514
           R+ I  P   +     ++++F
Sbjct: 417 RVVITVPEVMMLEACSRIQEF 437


>gi|187936925 1-aminocyclopropane-1-carboxylate synthase homolog
           [Homo sapiens]
          Length = 501

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 50/179 (27%), Positives = 86/179 (48%), Gaps = 13/179 (7%)

Query: 146 SLGSYSASQGVNCIREDVAAYITRR-DGGVPADPDNIYLTTGASDGISTILKILVSGGGK 204
           SL  Y+  +G   +RE+VA +++      VP  P+N+ +  G +   S +  +L   G  
Sbjct: 128 SLLQYADWRGHLFLREEVAKFLSFYCKSPVPLRPENVVVLNGGASLFSALATVLCEAG-- 185

Query: 205 SRTGVMIPIPQYPLYSAVISELDAIQVNY-YLDEE------NCWALNVNELRRAVQEA-K 256
                +IP P Y   +  +     I++ Y YLD E        + L V +L  A++EA  
Sbjct: 186 --EAFLIPTPYYGAITQHVCLYGNIRLAYVYLDSEVTGLDTRPFQLTVEKLEMALREAHS 243

Query: 257 DHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHS 315
           +    K L +I+P NP G V S + +++ + FA   +L ++ DEVY  +V+     + S
Sbjct: 244 EGVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSVGYRS 302


>gi|14211921 1-aminocyclopropane-1-carboxylate synthase homolog
           [Homo sapiens]
          Length = 501

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 50/179 (27%), Positives = 86/179 (48%), Gaps = 13/179 (7%)

Query: 146 SLGSYSASQGVNCIREDVAAYITRR-DGGVPADPDNIYLTTGASDGISTILKILVSGGGK 204
           SL  Y+  +G   +RE+VA +++      VP  P+N+ +  G +   S +  +L   G  
Sbjct: 128 SLLQYADWRGHLFLREEVAKFLSFYCKSPVPLRPENVVVLNGGASLFSALATVLCEAG-- 185

Query: 205 SRTGVMIPIPQYPLYSAVISELDAIQVNY-YLDEE------NCWALNVNELRRAVQEA-K 256
                +IP P Y   +  +     I++ Y YLD E        + L V +L  A++EA  
Sbjct: 186 --EAFLIPTPYYGAITQHVCLYGNIRLAYVYLDSEVTGLDTRPFQLTVEKLEMALREAHS 243

Query: 257 DHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHS 315
           +    K L +I+P NP G V S + +++ + FA   +L ++ DEVY  +V+     + S
Sbjct: 244 EGVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSVGYRS 302


>gi|149944424 1-aminocyclopropane-1-carboxylate synthase homolog
           (Arabidopsis)(non-functional)-like [Homo sapiens]
          Length = 568

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 47/185 (25%), Positives = 86/185 (46%), Gaps = 17/185 (9%)

Query: 142 CGGNSLGSYSASQGVNCIREDVAAYITRR-DGGVPADPDNIYLTTGASDGISTILKILVS 200
           C  ++L  Y   +G   +RE+VA ++T         DP+N+ +  G       +  +L  
Sbjct: 196 CIEDTLLQYPDWRGQPFLREEVARFLTYYCRAPTRLDPENVVVLNGCCSVFCALAMVLCD 255

Query: 201 GGGKSRTGVMIPIPQYPLY---SAVISELDAIQVNYYLDEE------NCWALNVNELRRA 251
            G       ++P P Y  +   S + ++++ I V  +L+ E      + + L V++L  A
Sbjct: 256 PG----EAFLVPAPFYGGFAFSSRLYAKVELIPV--HLESEVTVTNTHPFQLTVDKLEEA 309

Query: 252 VQEAK-DHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPD 310
           + EA+ +    + L +INP NP G + S   +   + FA    L ++ DE+Y  +V+   
Sbjct: 310 LLEARLEGKKVRGLVLINPQNPLGDIYSPDSLMKYLEFAKRYNLHVIIDEIYMLSVFDES 369

Query: 311 CRFHS 315
             FHS
Sbjct: 370 ITFHS 374


>gi|56713254 kynurenine aminotransferase III isoform 1 [Homo
           sapiens]
          Length = 454

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 18/137 (13%)

Query: 181 IYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEE-- 238
           I +T GA   +   ++ L+  G +    V++ +P Y  Y  ++    A  V   L  +  
Sbjct: 128 ILVTVGAYGSLFNTIQALIDEGDE----VILIVPFYDCYEPMVRMAGATPVFIPLRSKPV 183

Query: 239 -------NCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWE 291
                  + W L+  EL     E+K +   K + +  P NP G+V +R+ ++ +     +
Sbjct: 184 YGKRWSSSDWTLDPQEL-----ESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIK 238

Query: 292 EKLFLLADEVYQDNVYS 308
                ++DEVY+  VYS
Sbjct: 239 YDTLCISDEVYEWLVYS 255


>gi|56713256 kynurenine aminotransferase III isoform 2 [Homo
           sapiens]
          Length = 420

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 18/137 (13%)

Query: 181 IYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEE-- 238
           I +T GA   +   ++ L+  G +    V++ +P Y  Y  ++    A  V   L  +  
Sbjct: 94  ILVTVGAYGSLFNTIQALIDEGDE----VILIVPFYDCYEPMVRMAGATPVFIPLRSKPV 149

Query: 239 -------NCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWE 291
                  + W L+  EL     E+K +   K + +  P NP G+V +R+ ++ +     +
Sbjct: 150 YGKRWSSSDWTLDPQEL-----ESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIK 204

Query: 292 EKLFLLADEVYQDNVYS 308
                ++DEVY+  VYS
Sbjct: 205 YDTLCISDEVYEWLVYS 221


>gi|169881279 kynurenine aminotransferase I isoform a [Homo sapiens]
          Length = 422

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 47/193 (24%), Positives = 73/193 (37%), Gaps = 24/193 (12%)

Query: 125 PSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLT 184
           P F  +A + A       G   L  Y+ + G   + + +A++     G       N+ +T
Sbjct: 43  PDFAVEAFQHA-----VSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVT 97

Query: 185 TGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQV----------NYY 234
            G    + T  + LV  G +    V+I  P +  Y  +        V          N  
Sbjct: 98  VGGYGALFTAFQALVDEGDE----VIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153

Query: 235 LDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKL 294
           L   + W L+  EL       K     K L +  P NP G+V SR+ +E V     +  +
Sbjct: 154 LGSSSNWQLDPMELA-----GKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDV 208

Query: 295 FLLADEVYQDNVY 307
             + DEVYQ  VY
Sbjct: 209 VCITDEVYQWMVY 221


>gi|95147551 kynurenine aminotransferase I isoform a [Homo sapiens]
          Length = 422

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 47/193 (24%), Positives = 73/193 (37%), Gaps = 24/193 (12%)

Query: 125 PSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLT 184
           P F  +A + A       G   L  Y+ + G   + + +A++     G       N+ +T
Sbjct: 43  PDFAVEAFQHA-----VSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVT 97

Query: 185 TGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQV----------NYY 234
            G    + T  + LV  G +    V+I  P +  Y  +        V          N  
Sbjct: 98  VGGYGALFTAFQALVDEGDE----VIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153

Query: 235 LDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKL 294
           L   + W L+  EL       K     K L +  P NP G+V SR+ +E V     +  +
Sbjct: 154 LGSSSNWQLDPMELA-----GKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDV 208

Query: 295 FLLADEVYQDNVY 307
             + DEVYQ  VY
Sbjct: 209 VCITDEVYQWMVY 221


>gi|169881281 kynurenine aminotransferase I isoform b [Homo sapiens]
          Length = 372

 Score = 34.7 bits (78), Expect = 0.22
 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 232 NYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWE 291
           N  L   + W L+  EL       K     K L +  P NP G+V SR+ +E V     +
Sbjct: 101 NGELGSSSNWQLDPMELA-----GKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQ 155

Query: 292 EKLFLLADEVYQDNVY 307
             +  + DEVYQ  VY
Sbjct: 156 HDVVCITDEVYQWMVY 171


>gi|148727286 acyl-CoA thioesterase 2 [Homo sapiens]
          Length = 483

 Score = 30.4 bits (67), Expect = 4.1
 Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 10/108 (9%)

Query: 354 MEVINLHPEIKGQLVKLLSV----RLCPPVSG---QAAMDIVVNPPVAGEESFEQFSREK 406
           M  +  HPE+KG  V LL +     LC  ++         +V+N  VA       +  E 
Sbjct: 274 MNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLHYKGET 333

Query: 407 ESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEA 454
              +G    + K+T+D +  +  +  +PL+G      + FIP +  E+
Sbjct: 334 LPPVGVNRNRIKVTKDGYADIVDVLNSPLEG---PDQKSFIPVERAES 378


>gi|81230485 acyl-CoA thioesterase 1 [Homo sapiens]
          Length = 421

 Score = 30.4 bits (67), Expect = 4.1
 Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 10/102 (9%)

Query: 360 HPEIKGQLVKLLSV----RLCPPVSG---QAAMDIVVNPPVAGEESFEQFSREKESVLGN 412
           HPE+KG  V LL +     LC  ++         +V+N  VA      ++  E    +G 
Sbjct: 218 HPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLRYKGETLPPVGV 277

Query: 413 LAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEA 454
              + K+T+D +  +  +  +PL+G      + FIP +  E+
Sbjct: 278 NRNRIKVTKDGYADIVDVLNSPLEG---PDQKSFIPVERAES 316


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 8/70 (11%)

Query: 349  YRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKES 408
            YR G  E++ LH EIK Q  +L +++ C        + +   P V+ EE   +F   ++ 
Sbjct: 940  YRKGQEEIVTLHAEIKAQKKELDTIQEC--------IKVKYAPIVSFEECERKFKATEKE 991

Query: 409  VLGNLAKKAK 418
            +   L+++ +
Sbjct: 992  LKDQLSEQTQ 1001


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 8/70 (11%)

Query: 349  YRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKES 408
            YR G  E++ LH EIK Q  +L +++ C        + +   P V+ EE   +F   ++ 
Sbjct: 953  YRKGQEEIVTLHAEIKAQKKELDTIQEC--------IKVKYAPIVSFEECERKFKATEKE 1004

Query: 409  VLGNLAKKAK 418
            +   L+++ +
Sbjct: 1005 LKDQLSEQTQ 1014


>gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]
          Length = 1280

 Score = 29.6 bits (65), Expect = 7.0
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 9/56 (16%)

Query: 212 PIPQYPLYSAVISELDAIQVNYYLDEENCWALN--------VNELRRAVQEAKDHC 259
           P+   PL+S+++ +    +V Y L    C++ N        +  LRR VQ  KD+C
Sbjct: 258 PVSVKPLHSSILGQDFCFEVTY-LSGSKCFSCNSASERDKWMENLRRTVQPNKDNC 312


>gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]
          Length = 1139

 Score = 29.6 bits (65), Expect = 7.0
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 9/56 (16%)

Query: 212 PIPQYPLYSAVISELDAIQVNYYLDEENCWALN--------VNELRRAVQEAKDHC 259
           P+   PL+S+++ +    +V Y L    C++ N        +  LRR VQ  KD+C
Sbjct: 110 PVSVKPLHSSILGQDFCFEVTY-LSGSKCFSCNSASERDKWMENLRRTVQPNKDNC 164


>gi|169217528 PREDICTED: similar to sidekick homolog 2 (chicken)
          [Homo sapiens]
          Length = 399

 Score = 29.3 bits (64), Expect = 9.2
 Identities = 13/36 (36%), Positives = 17/36 (47%)

Query: 12 CGPRTPSSWGRSQSSAAAEASAVLKVRPERSRRERI 47
          CG RTP  WG S+         + K+RP+   R  I
Sbjct: 22 CGHRTPFPWGPSEYPHGTSRGPLWKIRPQGPTRPLI 57


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,314,033
Number of Sequences: 37866
Number of extensions: 903808
Number of successful extensions: 2096
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2080
Number of HSP's gapped (non-prelim): 20
length of query: 523
length of database: 18,247,518
effective HSP length: 107
effective length of query: 416
effective length of database: 14,195,856
effective search space: 5905476096
effective search space used: 5905476096
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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