Search of human proteins with 190341074

Search of human proteins with 190341074

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190341074 pyridoxal-dependent decarboxylase domain
containing 1 [Homo sapiens]
         (788 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|190341074 pyridoxal-dependent decarboxylase domain containing...  1571   0.0  
gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens]             59   2e-08
gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens]       54   4e-07
gi|92110055 histidine decarboxylase [Homo sapiens]                     52   2e-06
gi|58331246 glutamate decarboxylase 1 isoform GAD67 [Homo sapiens]     47   5e-05
gi|197276620 glutamate decarboxylase 2 [Homo sapiens]                  47   9e-05
gi|4503875 glutamate decarboxylase 2 [Homo sapiens]                    47   9e-05
gi|132814448 dopa decarboxylase (aromatic L-amino acid decarboxy...    45   3e-04
gi|4503281 dopa decarboxylase (aromatic L-amino acid decarboxyla...    45   3e-04
gi|46852174 kinesin family member 3A [Homo sapiens]                    37   0.093
gi|122937388 MAX gene associated [Homo sapiens]                        36   0.16 
gi|191250771 spire homolog 1 isoform b [Homo sapiens]                  35   0.21 
gi|191250775 spire homolog 1 isoform c [Homo sapiens]                  35   0.21 
gi|197313732 pleckstrin homology-like domain, family B, member 2...    35   0.27 
gi|197313730 pleckstrin homology-like domain, family B, member 2...    35   0.27 
gi|191250773 spire homolog 1 isoform a [Homo sapiens]                  35   0.27 
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]              34   0.60 
gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens]        33   0.79 
gi|33359221 dyslexia susceptibility 2-like [Homo sapiens]              33   1.3  
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    33   1.3  
gi|110611218 ribosome binding protein 1 [Homo sapiens]                 32   1.8  
gi|110611220 ribosome binding protein 1 [Homo sapiens]                 32   1.8  
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]               32   2.3  
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]               32   2.3  
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ...    32   3.0  
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ...    32   3.0  
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom...    32   3.0  
gi|224465194 secernin 1 isoform a [Homo sapiens]                       32   3.0  
gi|224465192 secernin 1 isoform c [Homo sapiens]                       32   3.0  
gi|224465190 secernin 1 isoform b [Homo sapiens]                       32   3.0  

>gi|190341074 pyridoxal-dependent decarboxylase domain containing 1
           [Homo sapiens]
          Length = 788

 Score = 1571 bits (4069), Expect = 0.0
 Identities = 788/788 (100%), Positives = 788/788 (100%)

Query: 1   MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS 60
           MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
Sbjct: 1   MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS 60

Query: 61  ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD 120
           ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
Sbjct: 61  ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD 120

Query: 121 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA 180
           TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
Sbjct: 121 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA 180

Query: 181 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA 240
           AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
Sbjct: 181 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA 240

Query: 241 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG 300
           NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
Sbjct: 241 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG 300

Query: 301 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA 360
           PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
Sbjct: 301 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA 360

Query: 361 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR 420
           CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
Sbjct: 361 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR 420

Query: 421 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA 480
           ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
Sbjct: 421 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA 480

Query: 481 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE 540
           CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
Sbjct: 481 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE 540

Query: 541 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE 600
           GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
Sbjct: 541 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE 600

Query: 601 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG 660
           ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
Sbjct: 601 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG 660

Query: 661 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET 720
           RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
Sbjct: 661 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET 720

Query: 721 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ 780
           SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
Sbjct: 721 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ 780

Query: 781 VEGPESLR 788
           VEGPESLR
Sbjct: 781 VEGPESLR 788


>gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens]
          Length = 521

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 45/188 (23%), Positives = 79/188 (42%), Gaps = 21/188 (11%)

Query: 221 LEKLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVE---------- 270
           LEK +    + G  P L+ A +GT  +G  D +  + ++CE++ +WLHV+          
Sbjct: 252 LEKQVWQARKEGAAPFLVCATSGTTVLGAFDPLDEIADICERHSLWLHVDASWGGSALMS 311

Query: 271 --------GVNLATLALGYVSSSVLAAAKCDSMTMTPGPWLGLPAVPAVTLYKHDDPALT 322
                   G++ A          ++A  +C ++ +     L      A   Y        
Sbjct: 312 RKHRKLLHGIHRADSVAWNPHKMLMAGIQCCALLVKDKSDLLKKCYSAKASYLFQQDKFY 371

Query: 323 LVAGLTSNKPTDKLR---ALPLWLSLQYLGLDGFVERIKHACQLSQRLQESLKKVNYIKI 379
            V+  T +K     R   A   W++ + LG  G  ER+  A  LS+ L + +KK    K+
Sbjct: 372 DVSYDTGDKSIQCSRRPDAFKFWMTWKALGTLGLEERVNRALALSRYLVDEIKKREGFKL 431

Query: 380 LVEDELSS 387
           L+E E ++
Sbjct: 432 LMEPEYAN 439


>gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens]
          Length = 520

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 48/191 (25%), Positives = 83/191 (43%), Gaps = 29/191 (15%)

Query: 223 KLIKDDIER--------GRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNL 274
           K++ +D+ER        G +P L+ A +GT  +G  D +  + ++C+++G+WLHV+    
Sbjct: 245 KMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWG 304

Query: 275 ATLALGYVSSSVL-AAAKCDSMTMTPGPWLGLPAVPAVTLYK---------HDDPALTL- 323
            ++ L      +L    + DS+   P   L      +  L +         H   A  L 
Sbjct: 305 GSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLF 364

Query: 324 -------VAGLTSNKPTD---KLRALPLWLSLQYLGLDGFVERIKHACQLSQRLQESLKK 373
                  VA  T +K      ++  L LWL  +  G  G   RI  A  L++ L E +KK
Sbjct: 365 QQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKK 424

Query: 374 VNYIKILVEDE 384
               ++++E E
Sbjct: 425 REGFELVMEPE 435


>gi|92110055 histidine decarboxylase [Homo sapiens]
          Length = 662

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 42/191 (21%), Positives = 77/191 (40%), Gaps = 20/191 (10%)

Query: 221 LEKLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALG 280
           L+K I++D +RG +P+ + A  GT  V   D +  L  +C + G+WLH++     T  L 
Sbjct: 224 LQKAIEEDKQRGLVPVFVCATLGTTGVCAFDCLSELGPICAREGLWLHIDAAYAGTAFLC 283

Query: 281 YVSSSVLAAAK-CDSMTMTPGPWL-------GLPAVPAVTLYKHDDPALTLVAGLTSNKP 332
                 L   +  DS T  P  W+       G        L +        +    S   
Sbjct: 284 PEFRGFLKGIEYADSFTFNPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHANSGVA 343

Query: 333 TD----------KLRALPLWLSLQYLGLDGFVERIKHACQLSQRLQESLKKVNYIKILVE 382
           TD          + R++ LW  ++  G+      ++H  ++++  +  ++     +I  +
Sbjct: 344 TDFMHWQIPLSRRFRSVKLWFVIRSFGVKNLQAHVRHGTEMAKYFESLVRNDPSFEIPAK 403

Query: 383 DELSSPVVVFR 393
             L   +VVFR
Sbjct: 404 RHLG--LVVFR 412


>gi|58331246 glutamate decarboxylase 1 isoform GAD67 [Homo sapiens]
          Length = 594

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 65/285 (22%), Positives = 116/285 (40%), Gaps = 38/285 (13%)

Query: 219 AFLEKLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLA 278
           A  E  I +  ++G +P  + A AGT   G  D I  + ++CE+Y +WLHV+      L 
Sbjct: 322 ADFEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLL 381

Query: 279 LGYVSSSVL-AAAKCDSMTMTPGPWLGLPAVPAVTLYKHD---DPALTLVAGL------- 327
           +       L    + +S+T  P   +G+    +  L K          + AG        
Sbjct: 382 MSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQ 441

Query: 328 ------TSNKPTDKLRALPL---WLSLQYLGLDGFVERIKHACQLSQRLQESLKKVNYIK 378
                 T +K     R + +   WL  +  G  GF  +I    +L++ L   +K     +
Sbjct: 442 YDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFE 501

Query: 379 ILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGRERHSCDALNRWLGEQLKQ 438
           ++   E     V F +   +P S    + VP      S   RE+     L++ +  ++K 
Sbjct: 502 MVFNGEPEHTNVCFWY---IPQS---LRGVP-----DSPQRREK-----LHK-VAPKIKA 544

Query: 439 LVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVACIE 483
           L+  SG T++  + +G    F  ++ +    T+  D+D L+  IE
Sbjct: 545 LMMESGTTMVGYQPQGDKANFFRMVISNPAATQ-SDIDFLIEEIE 588


>gi|197276620 glutamate decarboxylase 2 [Homo sapiens]
          Length = 585

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 26/98 (26%), Positives = 50/98 (51%), Gaps = 1/98 (1%)

Query: 221 LEKLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALG 280
           LE+ I +  ++G +P L+ A AGT   G  D +  + ++C++Y IW+HV+      L + 
Sbjct: 315 LERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMS 374

Query: 281 YVSSSVLAAA-KCDSMTMTPGPWLGLPAVPAVTLYKHD 317
                 L+   + +S+T  P   +G+P   +  L + +
Sbjct: 375 RKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREE 412


>gi|4503875 glutamate decarboxylase 2 [Homo sapiens]
          Length = 585

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 26/98 (26%), Positives = 50/98 (51%), Gaps = 1/98 (1%)

Query: 221 LEKLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALG 280
           LE+ I +  ++G +P L+ A AGT   G  D +  + ++C++Y IW+HV+      L + 
Sbjct: 315 LERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMS 374

Query: 281 YVSSSVLAAA-KCDSMTMTPGPWLGLPAVPAVTLYKHD 317
                 L+   + +S+T  P   +G+P   +  L + +
Sbjct: 375 RKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREE 412


>gi|132814448 dopa decarboxylase (aromatic L-amino acid
           decarboxylase) [Homo sapiens]
          Length = 480

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 47/213 (22%), Positives = 79/213 (37%), Gaps = 26/213 (12%)

Query: 216 MDVAFLEKLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLA 275
           M  + L++ ++ D   G +P  +VA  GT      D +  +  +C +  IWLHV+     
Sbjct: 217 MRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAG 276

Query: 276 TLALGYVSSSVLAAAK-CDSMTMTPGPWL-------------------GLPAVPAVTLYK 315
           +  +      +L   +  DS    P  WL                        P    + 
Sbjct: 277 SAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHS 336

Query: 316 HDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHACQLSQRLQESLKKVN 375
           H D  L             + R+L +W   +  G+ G    I+   QLS   +  +++  
Sbjct: 337 HQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDP 396

Query: 376 YIKILVEDELSSPVVVFRFFQELPGSDPVFKAV 408
             +I VE  L   +V FR    L GS+ V +A+
Sbjct: 397 RFEICVEVILG--LVCFR----LKGSNKVNEAL 423


>gi|4503281 dopa decarboxylase (aromatic L-amino acid decarboxylase)
           [Homo sapiens]
          Length = 480

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 47/213 (22%), Positives = 79/213 (37%), Gaps = 26/213 (12%)

Query: 216 MDVAFLEKLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLA 275
           M  + L++ ++ D   G +P  +VA  GT      D +  +  +C +  IWLHV+     
Sbjct: 217 MRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAG 276

Query: 276 TLALGYVSSSVLAAAK-CDSMTMTPGPWL-------------------GLPAVPAVTLYK 315
           +  +      +L   +  DS    P  WL                        P    + 
Sbjct: 277 SAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHS 336

Query: 316 HDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHACQLSQRLQESLKKVN 375
           H D  L             + R+L +W   +  G+ G    I+   QLS   +  +++  
Sbjct: 337 HQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDP 396

Query: 376 YIKILVEDELSSPVVVFRFFQELPGSDPVFKAV 408
             +I VE  L   +V FR    L GS+ V +A+
Sbjct: 397 RFEICVEVILG--LVCFR----LKGSNKVNEAL 423


>gi|46852174 kinesin family member 3A [Homo sapiens]
          Length = 699

 Score = 36.6 bits (83), Expect = 0.093
 Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 2/142 (1%)

Query: 495 LREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPEGENIHAGLLKKLNE 554
           L  +F++E+E     L  +    SG  +   E  +D++  +  D E      G  K   +
Sbjct: 359 LLRQFQKEIEELKKKLE-EGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPD 417

Query: 555 LESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIEENSRLLENMTEVVR 614
              ++  KI  E K++++ L +     N   AEL +      +  +E+  LLE ++ + +
Sbjct: 418 KMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEK 477

Query: 615 KGIQEAQVELQKASE-ERLLEE 635
           K I      L KA E E+LLEE
Sbjct: 478 KVIVGGVDLLAKAEEQEKLLEE 499


>gi|122937388 MAX gene associated [Homo sapiens]
          Length = 3114

 Score = 35.8 bits (81), Expect = 0.16
 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 18/109 (16%)

Query: 669  SLESTEPIYVYKAQGAGV---TLPPTPSGSRTKQRLPGQKP-------------FKRSLR 712
            S   +E    Y + G  V   +L P  SGS    +LPGQKP              KR  +
Sbjct: 1963 SKTGSETKITYSSGGQPVGTASLIPLQSGSFALLQLPGQKPVPSSILQHVASLQMKRESQ 2022

Query: 713  GSDALSETSSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHT 761
              D   ET+S+   ++ +KV  L S  E +  EA+  + + GA + + T
Sbjct: 2023 NPDQKDETNSIKREQETKKV--LQSEGEAVDPEANVIKQNSGAATSEET 2069


>gi|191250771 spire homolog 1 isoform b [Homo sapiens]
          Length = 742

 Score = 35.4 bits (80), Expect = 0.21
 Identities = 42/134 (31%), Positives = 56/134 (41%), Gaps = 12/134 (8%)

Query: 661 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET 720
           R   L   + EST+ +        G+T     +G  T Q++P Q+  K+ LR        
Sbjct: 392 RRSRLDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQR--KKLLRAPTLAELD 449

Query: 721 SSVSHIEDLEKVERLS----SGPEQITLEASSTEGHPGAPSP-QHTDQTEAFQKGVPHPE 775
           SS S  E L K    S    S PE+  LEA ST   P    P   T Q E  Q     P+
Sbjct: 450 SSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQP----PQ 505

Query: 776 DDHS-QVEGPESLR 788
             HS + E P ++R
Sbjct: 506 RRHSIEKETPTNVR 519


>gi|191250775 spire homolog 1 isoform c [Homo sapiens]
          Length = 622

 Score = 35.4 bits (80), Expect = 0.21
 Identities = 42/134 (31%), Positives = 56/134 (41%), Gaps = 12/134 (8%)

Query: 661 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET 720
           R   L   + EST+ +        G+T     +G  T Q++P Q+  K+ LR        
Sbjct: 272 RRSRLDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQR--KKLLRAPTLAELD 329

Query: 721 SSVSHIEDLEKVERLS----SGPEQITLEASSTEGHPGAPSP-QHTDQTEAFQKGVPHPE 775
           SS S  E L K    S    S PE+  LEA ST   P    P   T Q E  Q     P+
Sbjct: 330 SSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQP----PQ 385

Query: 776 DDHS-QVEGPESLR 788
             HS + E P ++R
Sbjct: 386 RRHSIEKETPTNVR 399


>gi|197313732 pleckstrin homology-like domain, family B, member 2
           isoform a [Homo sapiens]
          Length = 1253

 Score = 35.0 bits (79), Expect = 0.27
 Identities = 33/140 (23%), Positives = 63/140 (45%), Gaps = 23/140 (16%)

Query: 420 RERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLV 479
           +E+   D LNR + E  K +V       + L+AE   L               E + +L 
Sbjct: 642 KEKEILDHLNRKIAELEKNIVGEKTKEKVKLDAEREKL---------------ERLQELY 686

Query: 480 ACIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDP 539
           +  E K  +  C   +RE+ +Q+++  A LL V+  ++  +   + EH +      + D 
Sbjct: 687 S--EQKTQLDNCPESMREQLQQQLKRDADLLDVESKHFEDLEFQQLEHES------RLDE 738

Query: 540 EGENIHAGLLKKLNELESDL 559
           E EN+   LL+++ E + ++
Sbjct: 739 EKENLTQQLLREVAEYQRNI 758


>gi|197313730 pleckstrin homology-like domain, family B, member 2
           isoform a [Homo sapiens]
          Length = 1253

 Score = 35.0 bits (79), Expect = 0.27
 Identities = 33/140 (23%), Positives = 63/140 (45%), Gaps = 23/140 (16%)

Query: 420 RERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLV 479
           +E+   D LNR + E  K +V       + L+AE   L               E + +L 
Sbjct: 642 KEKEILDHLNRKIAELEKNIVGEKTKEKVKLDAEREKL---------------ERLQELY 686

Query: 480 ACIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDP 539
           +  E K  +  C   +RE+ +Q+++  A LL V+  ++  +   + EH +      + D 
Sbjct: 687 S--EQKTQLDNCPESMREQLQQQLKRDADLLDVESKHFEDLEFQQLEHES------RLDE 738

Query: 540 EGENIHAGLLKKLNELESDL 559
           E EN+   LL+++ E + ++
Sbjct: 739 EKENLTQQLLREVAEYQRNI 758


>gi|191250773 spire homolog 1 isoform a [Homo sapiens]
          Length = 756

 Score = 35.0 bits (79), Expect = 0.27
 Identities = 40/124 (32%), Positives = 53/124 (42%), Gaps = 12/124 (9%)

Query: 671 ESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSETSSVSHIEDLE 730
           EST+ +        G+T     +G  T Q++P Q+  K+ LR        SS S  E L 
Sbjct: 416 ESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQR--KKLLRAPTLAELDSSESEEETLH 473

Query: 731 KVERLS----SGPEQITLEASSTEGHPGAPSP-QHTDQTEAFQKGVPHPEDDHS-QVEGP 784
           K    S    S PE+  LEA ST   P    P   T Q E  Q     P+  HS + E P
Sbjct: 474 KSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQP----PQRRHSIEKETP 529

Query: 785 ESLR 788
            ++R
Sbjct: 530 TNVR 533


>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
          Length = 636

 Score = 33.9 bits (76), Expect = 0.60
 Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 11/106 (10%)

Query: 590 ETIAATAREIEENSRLLENMTEVVRKG--IQEAQVELQKASE--ERLLEEGVLRQIPVVG 645
           E  AA  R ++ENSRL E M  +   G  ++E+Q+E  +  +  E L+++  L  +P   
Sbjct: 20  EASAAFERLVKENSRLKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNEL--LPPPS 77

Query: 646 SVLNWFSPVQALQKGRTFNLTAG----SLESTEPIYVYKAQGAGVT 687
             L  F P+  L  G+  N+TA     +  S +P  V K   +G +
Sbjct: 78  PSLGSFDPLAEL-TGKDSNVTASPTAPACPSDKPAPVQKPPSSGTS 122


>gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens]
          Length = 526

 Score = 33.5 bits (75), Expect = 0.79
 Identities = 28/113 (24%), Positives = 44/113 (38%), Gaps = 9/113 (7%)

Query: 675 PIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSETSSVSHIEDLEKVER 734
           P Y + + G   TLP +    RT+Q          +    + +  TS  + +      E 
Sbjct: 222 PGYTFTSPGMTTTLPSSVISQRTQQTSSQMPASSTAPSSQETVQPTSPATALRTPTLPET 281

Query: 735 LSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQVEGPESL 787
           +SS P      AS+T  +P  PSP     T A +      ED  +Q +  + L
Sbjct: 282 MSSSP----TAASTTHRYPKTPSP-----TVAHESNWAKCEDLETQTQSEKQL 325


>gi|33359221 dyslexia susceptibility 2-like [Homo sapiens]
          Length = 1049

 Score = 32.7 bits (73), Expect = 1.3
 Identities = 17/62 (27%), Positives = 29/62 (46%)

Query: 713 GSDALSETSSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVP 772
           GS  + +  ++S     +    LS GP+ ++++   +EG    PS Q    +E  Q  VP
Sbjct: 219 GSAEVHKAITISSPLTTDLTAELSGGPKNVSVQPEISEGLATTPSTQQVKSSEKTQIAVP 278

Query: 773 HP 774
            P
Sbjct: 279 QP 280


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 32.7 bits (73), Expect = 1.3
 Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 8/84 (9%)

Query: 5    LEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVSILQL 64
            LEK  +  + ++ +NLKE  + L+DS + T++ N K+L   +    L  + QDM  +LQL
Sbjct: 1148 LEK--ESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQL 1205

Query: 65   VQNLMHGDEDEEPQSPRIQNIGEQ 88
                   +E+EE      + + E+
Sbjct: 1206 ------KEEEEETNRQETEKLKEE 1223


>gi|110611218 ribosome binding protein 1 [Homo sapiens]
          Length = 977

 Score = 32.3 bits (72), Expect = 1.8
 Identities = 38/159 (23%), Positives = 71/159 (44%), Gaps = 24/159 (15%)

Query: 547 GLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIEENSRLL 606
           G L++     S LT +I    +S+++ L  G A D  D        A+ A   ++ +RL 
Sbjct: 508 GQLQEARAENSQLTERI----RSIEALLEAGQARDAQDVQ------ASQAEADQQQTRLK 557

Query: 607 ENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNW-----FSPVQALQKGR 661
           E  ++V   G+++  +EL++A E++ ++   LR+        NW      +  +   K +
Sbjct: 558 ELESQV--SGLEKEAIELREAVEQQKVKNNDLRE-------KNWKAMEALATAEQACKEK 608

Query: 662 TFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQR 700
             +LT    ES + + + +AQ     L   P  S   Q+
Sbjct: 609 LHSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQ 647


>gi|110611220 ribosome binding protein 1 [Homo sapiens]
          Length = 977

 Score = 32.3 bits (72), Expect = 1.8
 Identities = 38/159 (23%), Positives = 71/159 (44%), Gaps = 24/159 (15%)

Query: 547 GLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIEENSRLL 606
           G L++     S LT +I    +S+++ L  G A D  D        A+ A   ++ +RL 
Sbjct: 508 GQLQEARAENSQLTERI----RSIEALLEAGQARDAQDVQ------ASQAEADQQQTRLK 557

Query: 607 ENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNW-----FSPVQALQKGR 661
           E  ++V   G+++  +EL++A E++ ++   LR+        NW      +  +   K +
Sbjct: 558 ELESQV--SGLEKEAIELREAVEQQKVKNNDLRE-------KNWKAMEALATAEQACKEK 608

Query: 662 TFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQR 700
             +LT    ES + + + +AQ     L   P  S   Q+
Sbjct: 609 LHSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQ 647


>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
          Length = 2416

 Score = 32.0 bits (71), Expect = 2.3
 Identities = 31/130 (23%), Positives = 43/130 (33%), Gaps = 16/130 (12%)

Query: 666  TAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLP-------GQKPFKRSLRGSDALS 718
            TAG +    P+      G+GV +   P  S      P             R   GS  LS
Sbjct: 1961 TAGDISGATPVL----PGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLS 2016

Query: 719  ETSSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQ---TEA--FQKGVPH 773
            ET+S  H  +LE+   L      +T +       P       T     TEA       P 
Sbjct: 2017 ETTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPT 2076

Query: 774  PEDDHSQVEG 783
               D +++ G
Sbjct: 2077 ASGDRTEISG 2086


>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
          Length = 2317

 Score = 32.0 bits (71), Expect = 2.3
 Identities = 31/130 (23%), Positives = 43/130 (33%), Gaps = 16/130 (12%)

Query: 666  TAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLP-------GQKPFKRSLRGSDALS 718
            TAG +    P+      G+GV +   P  S      P             R   GS  LS
Sbjct: 1961 TAGDISGATPVL----PGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLS 2016

Query: 719  ETSSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQ---TEA--FQKGVPH 773
            ET+S  H  +LE+   L      +T +       P       T     TEA       P 
Sbjct: 2017 ETTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPT 2076

Query: 774  PEDDHSQVEG 783
               D +++ G
Sbjct: 2077 ASGDRTEISG 2086


>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
           sapiens]
          Length = 1614

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 7/89 (7%)

Query: 488 VLCCTLQLREEFKQEVEATAGLLYVDDPN-WSGIGVVRYEHAN------DDKSSLKSDPE 540
           + C +L L   F++ V+A  G+    DP  W+   ++ Y+ A+      DDK S+  DP 
Sbjct: 812 IRCPSLPLYLNFEKFVQAKGGIPENIDPRTWALDRLIEYKDASIPVKEKDDKISVPEDPP 871

Query: 541 GENIHAGLLKKLNELESDLTFKIGPEYKS 569
                   LK  + +ESDL  ++   Y+S
Sbjct: 872 ERVKEPPKLKLNDYVESDLPQEVIKYYES 900


>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
           sapiens]
          Length = 1614

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 7/89 (7%)

Query: 488 VLCCTLQLREEFKQEVEATAGLLYVDDPN-WSGIGVVRYEHAN------DDKSSLKSDPE 540
           + C +L L   F++ V+A  G+    DP  W+   ++ Y+ A+      DDK S+  DP 
Sbjct: 812 IRCPSLPLYLNFEKFVQAKGGIPENIDPRTWALDRLIEYKDASIPVKEKDDKISVPEDPP 871

Query: 541 GENIHAGLLKKLNELESDLTFKIGPEYKS 569
                   LK  + +ESDL  ++   Y+S
Sbjct: 872 ERVKEPPKLKLNDYVESDLPQEVIKYYES 900


>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
           sapiens]
          Length = 1614

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 7/89 (7%)

Query: 488 VLCCTLQLREEFKQEVEATAGLLYVDDPN-WSGIGVVRYEHAN------DDKSSLKSDPE 540
           + C +L L   F++ V+A  G+    DP  W+   ++ Y+ A+      DDK S+  DP 
Sbjct: 812 IRCPSLPLYLNFEKFVQAKGGIPENIDPRTWALDRLIEYKDASIPVKEKDDKISVPEDPP 871

Query: 541 GENIHAGLLKKLNELESDLTFKIGPEYKS 569
                   LK  + +ESDL  ++   Y+S
Sbjct: 872 ERVKEPPKLKLNDYVESDLPQEVIKYYES 900


>gi|224465194 secernin 1 isoform a [Homo sapiens]
          Length = 414

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 18/62 (29%), Positives = 29/62 (46%)

Query: 57  DMVSILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTR 116
           D V ++   Q+   GD+D   + PR Q   ++ H     H     I   D+E+ RKL + 
Sbjct: 312 DDVKLVPKTQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAIIESDQEQGRKLRST 371

Query: 117 IL 118
           +L
Sbjct: 372 ML 373


>gi|224465192 secernin 1 isoform c [Homo sapiens]
          Length = 346

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 18/62 (29%), Positives = 29/62 (46%)

Query: 57  DMVSILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTR 116
           D V ++   Q+   GD+D   + PR Q   ++ H     H     I   D+E+ RKL + 
Sbjct: 244 DDVKLVPKTQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAIIESDQEQGRKLRST 303

Query: 117 IL 118
           +L
Sbjct: 304 ML 305


>gi|224465190 secernin 1 isoform b [Homo sapiens]
          Length = 434

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 18/62 (29%), Positives = 29/62 (46%)

Query: 57  DMVSILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTR 116
           D V ++   Q+   GD+D   + PR Q   ++ H     H     I   D+E+ RKL + 
Sbjct: 332 DDVKLVPKTQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAIIESDQEQGRKLRST 391

Query: 117 IL 118
           +L
Sbjct: 392 ML 393


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,379,408
Number of Sequences: 37866
Number of extensions: 1523407
Number of successful extensions: 5647
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 5585
Number of HSP's gapped (non-prelim): 100
length of query: 788
length of database: 18,247,518
effective HSP length: 110
effective length of query: 678
effective length of database: 14,082,258
effective search space: 9547770924
effective search space used: 9547770924
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.