Guide to the Human Genome
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Search of human proteins with 190014625

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190014625 DIS3 mitotic control isoform b [Homo sapiens]
         (928 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|190014625 DIS3 mitotic control isoform b [Homo sapiens]           1869   0.0  
gi|190014623 DIS3 mitotic control isoform a [Homo sapiens]           1803   0.0  
gi|219521928 DIS3 mitotic control homolog (S. cerevisiae)-like i...   510   e-144
gi|19115966 DIS3 mitotic control homolog (S. cerevisiae)-like is...   496   e-140
gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2...   347   2e-95
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ...   119   2e-26
gi|156105695 PPAR-alpha interacting complex protein 285 isoform ...   119   2e-26
gi|68160947 secretogranin II precursor [Homo sapiens]                  35   0.25 
gi|169201955 PREDICTED: similar to hCG1793014 [Homo sapiens]           33   1.6  
gi|169192125 PREDICTED: similar to UNCoordinated family member (...    33   1.6  
gi|198041777 Ran binding protein 11 isoform 1 [Homo sapiens]           33   1.6  
gi|39725950 Ran binding protein 11 isoform 2 [Homo sapiens]            33   1.6  
gi|60460889 Myb protein P42POP [Homo sapiens]                          32   2.1  
gi|217330592 LGP1 homolog isoform 2 [Homo sapiens]                     32   2.1  
gi|169214023 PREDICTED: hypothetical protein [Homo sapiens]            32   2.7  
gi|169214468 PREDICTED: hypothetical protein [Homo sapiens]            32   2.7  
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ...    32   2.7  
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ...    32   2.7  
gi|40255109 GrpE-like 2, mitochondrial [Homo sapiens]                  32   2.7  
gi|67782321 spectrin beta isoform a [Homo sapiens]                     32   3.6  
gi|67782319 spectrin beta isoform b [Homo sapiens]                     32   3.6  
gi|8922785 hypothetical protein LOC55267 [Homo sapiens]                32   3.6  
gi|23346412 cysteine-serine-rich nuclear protein 3 [Homo sapiens]      31   4.7  
gi|82617626 paralemmin 2 isoform b [Homo sapiens]                      31   4.7  
gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens]               31   4.7  
gi|124430557 a disintegrin-like and metalloprotease with thrombo...    31   4.7  
gi|28274682 zinc finger protein 33A isoform b [Homo sapiens]           31   4.7  
gi|110347446 zinc finger protein 33A isoform a [Homo sapiens]          31   4.7  
gi|24307875 zinc finger protein 33B [Homo sapiens]                     31   4.7  
gi|150010540 FERM domain containing 4B [Homo sapiens]                  31   6.1  

>gi|190014625 DIS3 mitotic control isoform b [Homo sapiens]
          Length = 928

 Score = 1869 bits (4841), Expect = 0.0
 Identities = 928/928 (100%), Positives = 928/928 (100%)

Query: 1   MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVC 60
           MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVC
Sbjct: 1   MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVC 60

Query: 61  PQPHYLLPDTNVLLHQIVSAWRPGTWASVASSLRLPGSLETYVEQEQGENANDRNDRAIR 120
           PQPHYLLPDTNVLLHQIVSAWRPGTWASVASSLRLPGSLETYVEQEQGENANDRNDRAIR
Sbjct: 61  PQPHYLLPDTNVLLHQIVSAWRPGTWASVASSLRLPGSLETYVEQEQGENANDRNDRAIR 120

Query: 121 VAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDR 180
           VAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDR
Sbjct: 121 VAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDR 180

Query: 181 LACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNE 240
           LACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNE
Sbjct: 181 LACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNE 240

Query: 241 ENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERML 300
           ENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERML
Sbjct: 241 ENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERML 300

Query: 301 KTAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQA 360
           KTAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQA
Sbjct: 301 KTAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQA 360

Query: 361 STLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLS 420
           STLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLS
Sbjct: 361 STLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLS 420

Query: 421 FLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVS 480
           FLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVS
Sbjct: 421 FLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVS 480

Query: 481 HFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNHNA 540
           HFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNHNA
Sbjct: 481 HFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNHNA 540

Query: 541 EILKTKFTKSVINSKASLTYAEAQLRIDSANMNDDITTSLRGLNKLAKILKKRRIEKGAL 600
           EILKTKFTKSVINSKASLTYAEAQLRIDSANMNDDITTSLRGLNKLAKILKKRRIEKGAL
Sbjct: 541 EILKTKFTKSVINSKASLTYAEAQLRIDSANMNDDITTSLRGLNKLAKILKKRRIEKGAL 600

Query: 601 TLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRK 660
           TLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRK
Sbjct: 601 TLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRK 660

Query: 661 HPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQ 720
           HPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQ
Sbjct: 661 HPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQ 720

Query: 721 AVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKL 780
           AVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKL
Sbjct: 721 AVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKL 780

Query: 781 ADICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLE 840
           ADICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLE
Sbjct: 781 ADICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLE 840

Query: 841 GTVFFEEKDKPNPQLIYDDEIPSLKIEDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLVEP 900
           GTVFFEEKDKPNPQLIYDDEIPSLKIEDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLVEP
Sbjct: 841 GTVFFEEKDKPNPQLIYDDEIPSLKIEDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLVEP 900

Query: 901 QIPGISIPTDTSNMDLNGPKKKKMKLGK 928
           QIPGISIPTDTSNMDLNGPKKKKMKLGK
Sbjct: 901 QIPGISIPTDTSNMDLNGPKKKKMKLGK 928


>gi|190014623 DIS3 mitotic control isoform a [Homo sapiens]
          Length = 958

 Score = 1803 bits (4671), Expect = 0.0
 Identities = 909/958 (94%), Positives = 912/958 (95%), Gaps = 30/958 (3%)

Query: 1   MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVC 60
           MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVC
Sbjct: 1   MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVC 60

Query: 61  PQPHYLLPDTNVLLHQIVSAWRPG-----TWASVASSLRLPGS----------------- 98
           PQPHYLLPDTNVLLHQI     P         +V   +R   +                 
Sbjct: 61  PQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHF 120

Query: 99  --------LETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN 150
                    ETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN
Sbjct: 121 YTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN 180

Query: 151 KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQG 210
           KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQG
Sbjct: 181 KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQG 240

Query: 211 IKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKS 270
           IKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKS
Sbjct: 241 IKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKS 300

Query: 271 QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML 330
           QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML
Sbjct: 301 QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML 360

Query: 331 SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNL 390
           SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNL
Sbjct: 361 SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNL 420

Query: 391 GDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP 450
           GDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP
Sbjct: 421 GDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP 480

Query: 451 PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMV 510
           PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMV
Sbjct: 481 PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMV 540

Query: 511 PELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSA 570
           PELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSA
Sbjct: 541 PELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSA 600

Query: 571 NMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETN 630
           NMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETN
Sbjct: 601 NMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETN 660

Query: 631 SMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKS 690
           SMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKS
Sbjct: 661 SMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKS 720

Query: 691 LAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIR 750
           LAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIR
Sbjct: 721 LAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIR 780

Query: 751 RYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFF 810
           RYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFF
Sbjct: 781 RYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFF 840

Query: 811 KSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTV 870
           KSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTV
Sbjct: 841 KSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTV 900

Query: 871 FHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK 928
           FHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK
Sbjct: 901 FHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK 958


>gi|219521928 DIS3 mitotic control homolog (S. cerevisiae)-like
           isoform 1 [Homo sapiens]
          Length = 1054

 Score =  510 bits (1314), Expect = e-144
 Identities = 348/1006 (34%), Positives = 527/1006 (52%), Gaps = 148/1006 (14%)

Query: 3   KSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGC---AACGGAHEGPALEPQPQDPASSV 59
           + K  L +T  G  ++IVREHYLR  + C +P C   AAC  +H+G  L       +S V
Sbjct: 5   REKVLLLRTFQGRTLRIVREHYLRPCVPCHSPLCPQPAAC--SHDGKLL-------SSDV 55

Query: 60  CPQPHYLLPDTNVLLHQIVSAWRPGTWASVASSL---------------RLPGSLET--- 101
               HY++PD  V+   +     P     +                   +L   L+    
Sbjct: 56  T---HYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARH 112

Query: 102 -------------YVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDR 148
                        Y+ +E+GE+      R+I  AA WY  H +     +++ ++ +T D 
Sbjct: 113 DCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQ-----DRMPIVMVTED- 166

Query: 149 RNKEKAIE------EGIPAFTCEEYVKS----LTANPELIDRL--ACLSEEGNEIESGKI 196
              E+AI+      EG+   T + Y+ +    L A  EL D +  +    E    ES   
Sbjct: 167 ---EEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGK 223

Query: 197 IFSEHLPLSKLQQGIKSGTYLQGTFRASREN-YLEATVWIHG----DNEENKEIILQGLK 251
            + EHLPL  L+ GIKSG Y+QG    ++    +EA V + G    D++   +I++ G+K
Sbjct: 224 EYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMK 283

Query: 252 HLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKP 311
             NR++H D+V VELLPK++W   +  +  ++  ++   E   E               P
Sbjct: 284 ARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEP-------------MP 330

Query: 312 TGRVVGIIKRNWRPYCGML-SKSDI----KESRRHLFTPADKRIPRIRIETRQASTLEGR 366
           TGRVVGI+++NWR Y     SK ++    K +++ L TP D RIP+IRI T+QA TL+  
Sbjct: 331 TGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDF 390

Query: 367 RIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLP--- 423
           R++V ID W   S YPNGHFVR LG +G+ E E   +L+E+ +   PFS+A +  +P   
Sbjct: 391 RVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNT 450

Query: 424 -KMPWSITEKDMKNREDLR--HLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVS 480
            + PW ++ ++ + R+DLR  HL + S+DP GC D+DD L  R L NGNLE+GVHIADV+
Sbjct: 451 PESPWKVSPEEEQKRKDLRKSHL-VFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVT 509

Query: 481 HFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNH-N 539
           HF+ P + +D E+  R TT YL ++R DM+P +LS++LCSL   VDR A S +WE++  +
Sbjct: 510 HFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKAS 569

Query: 540 AEILKTKFTKSVINSKASLTYAEAQLRID-SANMNDDI------------------TTSL 580
            EI K  + +++I S   L Y  AQ  +D + ++ DDI                    ++
Sbjct: 570 YEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAI 629

Query: 581 RGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSE--THDPIDLQTKELRETNSMVEEFML 638
             L  +A+ ++ +R   GAL L   EV   +D +   HD I  Q  E+ ET   V E M+
Sbjct: 630 GKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHET---VAECMI 686

Query: 639 LANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQA 698
           LAN  VAKKI E F   ALLR+HP P    +  L + A+++   I T + K+LA+SLD A
Sbjct: 687 LANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNA 746

Query: 699 ESPTFPYLNTLLRILATRCMMQAVYFCSG--MDNDFHHYGLASPIYTHFTSPIRRYADVI 756
             P  P +N LLR +AT+ M  A+YF +G   + +FHHYGLA   YTHFTSPIRRY+D++
Sbjct: 747 NDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIV 806

Query: 757 VHRLLAVAIGADCTYP---ELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFFKSK 813
           VHRLL  AI  D        L     L ++C+++N R++ AQ++Q+ S      ++FK K
Sbjct: 807 VHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDK 866

Query: 814 GIVSEE-----AYILFVRKNAIVVLIPKYGLEGTVFFEEKD--------------KPNPQ 854
              +EE       I  +R N +++ IP++G++G  + + KD              KP   
Sbjct: 867 DPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSL 926

Query: 855 LIYDDEIPSLKI--EDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLV 898
             + ++I S     E   FH+FD V V+I + +S      IR+ ++
Sbjct: 927 QRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEII 972


>gi|19115966 DIS3 mitotic control homolog (S. cerevisiae)-like
           isoform 2 [Homo sapiens]
          Length = 971

 Score =  496 bits (1278), Expect = e-140
 Identities = 317/873 (36%), Positives = 480/873 (54%), Gaps = 102/873 (11%)

Query: 102 YVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIE----- 156
           Y+ +E+GE+      R+I  AA WY  H +     +++ ++ +T D    E+AI+     
Sbjct: 43  YLPRERGESMEKWQTRSIYNAAVWYYHHCQ-----DRMPIVMVTED----EEAIQQYGSE 93

Query: 157 -EGIPAFTCEEYVKS----LTANPELIDRL--ACLSEEGNEIESGKIIFSEHLPLSKLQQ 209
            EG+   T + Y+ +    L A  EL D +  +    E    ES    + EHLPL  L+ 
Sbjct: 94  TEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEA 153

Query: 210 GIKSGTYLQGTFRASREN-YLEATVWIHG----DNEENKEIILQGLKHLNRAVHEDIVAV 264
           GIKSG Y+QG    ++    +EA V + G    D++   +I++ G+K  NR++H D+V V
Sbjct: 154 GIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVV 213

Query: 265 ELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWR 324
           ELLPK++W   +  +  ++  ++   E   E               PTGRVVGI+++NWR
Sbjct: 214 ELLPKNEWKGRTVALCENDCDDKASGESPSEP-------------MPTGRVVGILQKNWR 260

Query: 325 PYCGML-SKSDI----KESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNS 379
            Y     SK ++    K +++ L TP D RIP+IRI T+QA TL+  R++V ID W   S
Sbjct: 261 DYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTS 320

Query: 380 RYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLP----KMPWSITEKDMK 435
            YPNGHFVR LG +G+ E E   +L+E+ +   PFS+A +  +P    + PW ++ ++ +
Sbjct: 321 VYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQ 380

Query: 436 NREDLR--HLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQES 493
            R+DLR  HL + S+DP GC D+DD L  R L NGNLE+GVHIADV+HF+ P + +D E+
Sbjct: 381 KRKDLRKSHL-VFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEA 439

Query: 494 ARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNH-NAEILKTKFTKSVI 552
             R TT YL ++R DM+P +LS++LCSL   VDR A S +WE++  + EI K  + +++I
Sbjct: 440 RTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTII 499

Query: 553 NSKASLTYAEAQLRID-SANMNDDI------------------TTSLRGLNKLAKILKKR 593
            S   L Y  AQ  +D + ++ DDI                    ++  L  +A+ ++ +
Sbjct: 500 RSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAK 559

Query: 594 RIEKGALTLSSPEVRFHMDSE--THDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEE 651
           R   GAL L   EV   +D +   HD I  Q  E+ ET   V E M+LAN  VAKKI E 
Sbjct: 560 RDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHET---VAECMILANHWVAKKIWES 616

Query: 652 FSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLR 711
           F   ALLR+HP P    +  L + A+++   I T + K+LA+SLD A  P  P +N LLR
Sbjct: 617 FPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLR 676

Query: 712 ILATRCMMQAVYFCSG--MDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADC 769
            +AT+ M  A+YF +G   + +FHHYGLA   YTHFTSPIRRY+D++VHRLL  AI  D 
Sbjct: 677 SMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDK 736

Query: 770 TYP---ELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEE-----AY 821
                  L     L ++C+++N R++ AQ++Q+ S      ++FK K   +EE       
Sbjct: 737 KMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGV 796

Query: 822 ILFVRKNAIVVLIPKYGLEGTVFFEEKD--------------KPNPQLIYDDEIPSLKI- 866
           I  +R N +++ IP++G++G  + + KD              KP     + ++I S    
Sbjct: 797 IYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTD 856

Query: 867 -EDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLV 898
            E   FH+FD V V+I + +S      IR+ ++
Sbjct: 857 GESVTFHLFDHVTVRISIQASRCHSDTIRLEII 889


>gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2
           [Homo sapiens]
          Length = 885

 Score =  347 bits (891), Expect = 2e-95
 Identities = 239/674 (35%), Positives = 352/674 (52%), Gaps = 68/674 (10%)

Query: 277 SVVLHDEGQNEED--VEKEEETERMLKT-AVSEKMLKPTGRVVGII-KRNWRPYCGMLSK 332
           SV + ++G+ + D  V K+E T     T A+SEK L+ + +VV I+ K++ R   G L  
Sbjct: 194 SVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKL 253

Query: 333 SDIKES----RRHLFTPADKRIPRIRIETRQ------------ASTLEGRRIIVAIDGWP 376
              K S    +  LF+P+D R+PRI +  +             A+TL     I  I  W 
Sbjct: 254 LADKNSELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTL----FICRIVDWK 309

Query: 377 RNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPK-MPWSITEKDMK 435
            +  +  G   ++LG  GE E ETE +L E+ V    FS  VL  LP+ +PW+I  ++  
Sbjct: 310 EDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLPWTIPPEEFS 369

Query: 436 NREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESAR 495
            R DLR  CI ++DP    D+DDAL C+ L +GN +VGVHIADVS+F+  G+ LD+ +A 
Sbjct: 370 KRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAE 429

Query: 496 RGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSK 555
           R T+VYL +K + M+P LL   LCSL    D+L FS IW +    +IL   F +++I S 
Sbjct: 430 RATSVYLVQKVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSC 489

Query: 556 ASLTYAEAQLRIDS---------------ANMNDDITTSLRGLNKLAKILKKRRIEKGAL 600
             L+Y  AQ  I+S                + ++++  ++  L+ +AK L+++R   GAL
Sbjct: 490 TKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLRQQRFVDGAL 549

Query: 601 TLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRK 660
            L   ++ F +D ET  P      E RE+N +VEEFMLLAN++VA KIH  F E ALLR+
Sbjct: 550 RLDQLKLAFTLDHETGLPQGCHIYEYRESNKLVEEFMLLANMAVAHKIHRAFPEQALLRR 609

Query: 661 HPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYL--NTLLRILATRCM 718
           HP P       LV+      L +   +A +L +SL Q        L    +L  + +R M
Sbjct: 610 HPPPQTRMLSDLVEFCDQMGLPVDFSSAGALNKSLTQTFGDDKYSLARKEVLTNMCSRPM 669

Query: 719 MQAVYFCSGMDND---FHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELT 775
             A+YFCSG+  D   F HY L  P+YTHFTSPIRR+ADV+VHRLLA A+G    Y E  
Sbjct: 670 QMALYFCSGLLQDPAQFRHYALNVPLYTHFTSPIRRFADVLVHRLLAAALG----YRERL 725

Query: 776 DK-----HKLADICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAI 830
           D       K AD C   N R   ++  Q  S +    +  K  G +  EA ++ + K A 
Sbjct: 726 DMAPDTLQKQADHC---NDRRMASKRVQELSTSLFFAVLVKESGPLESEAMVMGILKQAF 782

Query: 831 VVLIPKYGLEGTV-----------FFEEKDKPNPQLIYDDEIPSLKIEDTVFHVFDKVKV 879
            VL+ +YG++  +           F +   KP   L+++ E    +    V  +F  V+V
Sbjct: 783 DVLVLRYGVQKRIYCNALALRSHHFQKVGKKPELTLVWEPEDMEQEPAQQVITIFSLVEV 842

Query: 880 KIMLDSSNLQHQKI 893
            +  +S+ L++  I
Sbjct: 843 VLQAESTALKYSAI 856



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 31/101 (30%), Positives = 54/101 (53%), Gaps = 5/101 (4%)

Query: 195 KIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLN 254
           K IF  ++    + +G+K GT +QG  R + + + EA +      + +++I + G+   N
Sbjct: 47  KSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFI---PSPDGDRDIFIDGVVARN 103

Query: 255 RAVHEDIVAVELLPKSQW--VAPSSVVLHDEGQNEEDVEKE 293
           RA++ D+V V+LLP+  W  V P S     E   E D+ +E
Sbjct: 104 RALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEE 144


>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
            [Homo sapiens]
          Length = 2649

 Score =  119 bits (297), Expect = 2e-26
 Identities = 136/568 (23%), Positives = 224/568 (39%), Gaps = 87/568 (15%)

Query: 313  GRVVGIIKRN------------WRPYC-----GMLSKSDIKE----SRRHLFTPADKRIP 351
            GRV+G++KR             W P       G ++K  + E    S+  +++    R+ 
Sbjct: 1189 GRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDPSQVPIYSLRKGRLQ 1248

Query: 352  RIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPH 411
            R+ +E   A     R   V I  W +   YP G     L +    E    +L LE+ +  
Sbjct: 1249 RVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRV 1308

Query: 412  QPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLE 471
             P  QA ++ + +   +   +    RED R     +VDP G  ++DDAL  R+L     E
Sbjct: 1309 PPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDL-GPRCE 1367

Query: 472  VGVHIADVSHFIRPGNALDQESARRGTTVYLCEKR-IDMVPELLSSNLCSLKCDVDRLAF 530
            V VHI DV+ F+     LD E+ R+G   Y   +  + M+P  L  ++ SL    DRLA 
Sbjct: 1368 VAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAI 1427

Query: 531  SCIWEMNHNAEILKT-KFTKSVINSKASLTYAEAQLRI--------DSANMNDDITTSLR 581
            S    M   +  LK+ +F  SV+ S   L+Y EA+  I        +     D +   + 
Sbjct: 1428 SLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVV 1487

Query: 582  GLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLAN 641
                 +++L++ R+                D     P +  T   R  + MV+E+M+  N
Sbjct: 1488 AACYFSRLLRRHRLRS--------------DCFYEQPDEDGTLGFRAAHIMVKEYMIQFN 1533

Query: 642  ISVA--------------------------KKIHEEFSEHALLRKH---------PAPPP 666
              VA                          K + E+  +   L  H          +PP 
Sbjct: 1534 RLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPD 1593

Query: 667  SNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCS 726
            +   +L    +      +T   + + + +        P+L    R L       A   C+
Sbjct: 1594 TRLHLLASLWKQVQFAARTQDYEQMVDLV--TTDDMHPFLAPAGRDLRKALERSAFGRCA 1651

Query: 727  -GMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICK 785
             G      HY L    YT  TSPIRRY DV++ R + +A+G   +     D   +  +C+
Sbjct: 1652 RGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARD---IDGLCQ 1708

Query: 786  NLNFRHKMAQYAQRASVAFHTQLFFKSK 813
              + +H +AQ  QR + + H  +  K++
Sbjct: 1709 AFSLQHALAQSYQRRARSLHLAVQLKAQ 1736


>gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2
            [Homo sapiens]
          Length = 2080

 Score =  119 bits (297), Expect = 2e-26
 Identities = 136/568 (23%), Positives = 224/568 (39%), Gaps = 87/568 (15%)

Query: 313  GRVVGIIKRN------------WRPYC-----GMLSKSDIKE----SRRHLFTPADKRIP 351
            GRV+G++KR             W P       G ++K  + E    S+  +++    R+ 
Sbjct: 620  GRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDPSQVPIYSLRKGRLQ 679

Query: 352  RIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPH 411
            R+ +E   A     R   V I  W +   YP G     L +    E    +L LE+ +  
Sbjct: 680  RVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRV 739

Query: 412  QPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLE 471
             P  QA ++ + +   +   +    RED R     +VDP G  ++DDAL  R+L     E
Sbjct: 740  PPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDL-GPRCE 798

Query: 472  VGVHIADVSHFIRPGNALDQESARRGTTVYLCEKR-IDMVPELLSSNLCSLKCDVDRLAF 530
            V VHI DV+ F+     LD E+ R+G   Y   +  + M+P  L  ++ SL    DRLA 
Sbjct: 799  VAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAI 858

Query: 531  SCIWEMNHNAEILKT-KFTKSVINSKASLTYAEAQLRI--------DSANMNDDITTSLR 581
            S    M   +  LK+ +F  SV+ S   L+Y EA+  I        +     D +   + 
Sbjct: 859  SLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVV 918

Query: 582  GLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLAN 641
                 +++L++ R+                D     P +  T   R  + MV+E+M+  N
Sbjct: 919  AACYFSRLLRRHRLRS--------------DCFYEQPDEDGTLGFRAAHIMVKEYMIQFN 964

Query: 642  ISVA--------------------------KKIHEEFSEHALLRKH---------PAPPP 666
              VA                          K + E+  +   L  H          +PP 
Sbjct: 965  RLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPD 1024

Query: 667  SNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCS 726
            +   +L    +      +T   + + + +        P+L    R L       A   C+
Sbjct: 1025 TRLHLLASLWKQVQFAARTQDYEQMVDLV--TTDDMHPFLAPAGRDLRKALERSAFGRCA 1082

Query: 727  -GMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICK 785
             G      HY L    YT  TSPIRRY DV++ R + +A+G   +     D   +  +C+
Sbjct: 1083 RGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARD---IDGLCQ 1139

Query: 786  NLNFRHKMAQYAQRASVAFHTQLFFKSK 813
              + +H +AQ  QR + + H  +  K++
Sbjct: 1140 AFSLQHALAQSYQRRARSLHLAVQLKAQ 1167


>gi|68160947 secretogranin II precursor [Homo sapiens]
          Length = 617

 Score = 35.4 bits (80), Expect = 0.25
 Identities = 24/100 (24%), Positives = 53/100 (53%), Gaps = 6/100 (6%)

Query: 224 SRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVV--LH 281
           SR N L    WI   + EN+++  + L   ++ + E +    +L K   +  S+ V  + 
Sbjct: 473 SRSNQLPKAAWI--PHVENRQMAYENLNDKDQELGEYLA--RMLVKYPEIINSNQVKRVP 528

Query: 282 DEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKR 321
            +G +E+D+++EE+ E+ +K  +++   + T ++  + KR
Sbjct: 529 GQGSSEDDLQEEEQIEQAIKEHLNQGSSQETDKLAPVSKR 568


>gi|169201955 PREDICTED: similar to hCG1793014 [Homo sapiens]
          Length = 366

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 14/30 (46%), Positives = 15/30 (50%)

Query: 33  APGCAACGGAHEGPALEPQPQDPASSVCPQ 62
           APG    GG   GP L P P  P S  CP+
Sbjct: 293 APGKVTLGGPRAGPPLAPAPPPPQSGRCPR 322


>gi|169192125 PREDICTED: similar to UNCoordinated family member
           (unc-44) [Homo sapiens]
          Length = 393

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 14/30 (46%), Positives = 15/30 (50%)

Query: 33  APGCAACGGAHEGPALEPQPQDPASSVCPQ 62
           APG    GG   GP L P P  P S  CP+
Sbjct: 320 APGKVTLGGPRAGPPLAPAPPPPQSGRCPR 349


>gi|198041777 Ran binding protein 11 isoform 1 [Homo sapiens]
          Length = 1015

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 666 PSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPT---FPYLNTLLRILATRCMMQAV 722
           P  YE +    + ++L ++ +TA +L  ++D  E  T    PYL T+  +L    ++Q V
Sbjct: 554 PMLYEAICNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLETMFTLLFQ--LLQQV 611

Query: 723 YFCSGMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRL 760
             C   D   H   + S +       IR Y   +V  L
Sbjct: 612 TEC---DTKMHVLHVLSCVIERVNMQIRPYVGCLVQYL 646


>gi|39725950 Ran binding protein 11 isoform 2 [Homo sapiens]
          Length = 975

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 666 PSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPT---FPYLNTLLRILATRCMMQAV 722
           P  YE +    + ++L ++ +TA +L  ++D  E  T    PYL T+  +L    ++Q V
Sbjct: 514 PMLYEAICNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLETMFTLLFQ--LLQQV 571

Query: 723 YFCSGMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRL 760
             C   D   H   + S +       IR Y   +V  L
Sbjct: 572 TEC---DTKMHVLHVLSCVIERVNMQIRPYVGCLVQYL 606


>gi|60460889 Myb protein P42POP [Homo sapiens]
          Length = 399

 Score = 32.3 bits (72), Expect = 2.1
 Identities = 23/64 (35%), Positives = 26/64 (40%), Gaps = 9/64 (14%)

Query: 30  GCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPD------TNVLLHQIVSAWRP 83
           G  APG  A  GA E PA  P  Q P  S CPQ + L  D       +   H    +  P
Sbjct: 123 GVAAPGAGA--GAEEPPAA-PSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSP 179

Query: 84  GTWA 87
             WA
Sbjct: 180 EPWA 183


>gi|217330592 LGP1 homolog isoform 2 [Homo sapiens]
          Length = 491

 Score = 32.3 bits (72), Expect = 2.1
 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 10/80 (12%)

Query: 324 RPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPN 383
           RP+C +   +DI   R HL  P  K  P +  + R A        +     WPR   +P 
Sbjct: 79  RPHCSLRRSTDISTFRNHL--PLTKAYPEVLAQGRTAR-------VTLTSPWPRPLPWP- 128

Query: 384 GHFVRNLGDVGEKETETEVL 403
           G+ +  +G  G K+    +L
Sbjct: 129 GNTLGQVGTPGTKDPRALLL 148


>gi|169214023 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 193

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 9/57 (15%)

Query: 45  GPALEPQPQ---DPASSVCPQPHYLLPDTNVLLHQIVSAWRPGTWASVASSLRLPGS 98
           GPAL P+PQ    P+S+  P PH  +P       +  S W P  W +      L G+
Sbjct: 50  GPALRPRPQPKAPPSSAAPPTPHSSIPP------RPPSPWGPRVWGAPTHRPALKGT 100


>gi|169214468 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 193

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 9/57 (15%)

Query: 45  GPALEPQPQ---DPASSVCPQPHYLLPDTNVLLHQIVSAWRPGTWASVASSLRLPGS 98
           GPAL P+PQ    P+S+  P PH  +P       +  S W P  W +      L G+
Sbjct: 50  GPALRPRPQPKAPPSSAAPPTPHSSIPP------RPPSPWGPRVWGAPTHRPALKGT 100


>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
           sapiens]
          Length = 2155

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 5/107 (4%)

Query: 67  LPDTNVLLHQIVSAWRPGTWASVASSLRLPGSLETYVEQEQGENANDRNDRAIRVAAKWY 126
           +P    L+  I  AW     A     L L   L   + QE+ E    R DR   +   W 
Sbjct: 369 MPREGKLISDINKAWERLEKAEHERELALRNEL---IRQEKLEQLARRFDRKAAMRETWL 425

Query: 127 NEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTA 173
           +E+ + +S DN    +        K +AIE  I A+  EE V+++ A
Sbjct: 426 SENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAY--EERVQAVVA 470


>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
           sapiens]
          Length = 2364

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 5/107 (4%)

Query: 67  LPDTNVLLHQIVSAWRPGTWASVASSLRLPGSLETYVEQEQGENANDRNDRAIRVAAKWY 126
           +P    L+  I  AW     A     L L   L   + QE+ E    R DR   +   W 
Sbjct: 382 MPREGKLISDINKAWERLEKAEHERELALRNEL---IRQEKLEQLARRFDRKAAMRETWL 438

Query: 127 NEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTA 173
           +E+ + +S DN    +        K +AIE  I A+  EE V+++ A
Sbjct: 439 SENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAY--EERVQAVVA 483


>gi|40255109 GrpE-like 2, mitochondrial [Homo sapiens]
          Length = 225

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 26/122 (21%), Positives = 54/122 (44%), Gaps = 13/122 (10%)

Query: 86  WASVASSLRLPGSLETYVEQEQGENANDRN----------DRAIRVAAKWYNEHLKKMSA 135
           W++   S   P    T  ++  GE+    +          +RA+RV A    + ++ ++ 
Sbjct: 19  WSAAWESKGWPLPFSTATQRTAGEDCRSEDPPDELGPPLAERALRVKAVKLEKEVQDLTV 78

Query: 136 DNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDRLA-CLSEEGNEIESG 194
             Q  +    N RR  ++ +E+    F  + + K L    +++++   C+SEE +E E  
Sbjct: 79  RYQRAIADCENIRRRTQRCVEDA-KIFGIQSFCKDLVEVADILEKTTECISEE-SEPEDQ 136

Query: 195 KI 196
           K+
Sbjct: 137 KL 138


>gi|67782321 spectrin beta isoform a [Homo sapiens]
          Length = 2328

 Score = 31.6 bits (70), Expect = 3.6
 Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 5/104 (4%)

Query: 68  PDTNVLLHQIVSAWRPGTWASVASSLRLPGSLETYVEQEQGENANDRNDRAIRVAAKWYN 127
           P    L+  I  AW     A     L L   L   + QE+ E    R DR   +   W +
Sbjct: 383 PHDGKLVSDINRAWESLEEAEYRRELALRNEL---IRQEKLEQLARRFDRKAAMRETWLS 439

Query: 128 EHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSL 171
           E+ + ++ DN    +      + K +AIE    A+  EE V++L
Sbjct: 440 ENQRLVAQDNFGYDLAAVEAAKKKHEAIETDTAAY--EERVRAL 481


>gi|67782319 spectrin beta isoform b [Homo sapiens]
          Length = 2137

 Score = 31.6 bits (70), Expect = 3.6
 Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 5/104 (4%)

Query: 68  PDTNVLLHQIVSAWRPGTWASVASSLRLPGSLETYVEQEQGENANDRNDRAIRVAAKWYN 127
           P    L+  I  AW     A     L L   L   + QE+ E    R DR   +   W +
Sbjct: 383 PHDGKLVSDINRAWESLEEAEYRRELALRNEL---IRQEKLEQLARRFDRKAAMRETWLS 439

Query: 128 EHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSL 171
           E+ + ++ DN    +      + K +AIE    A+  EE V++L
Sbjct: 440 ENQRLVAQDNFGYDLAAVEAAKKKHEAIETDTAAY--EERVRAL 481


>gi|8922785 hypothetical protein LOC55267 [Homo sapiens]
          Length = 138

 Score = 31.6 bits (70), Expect = 3.6
 Identities = 20/67 (29%), Positives = 26/67 (38%), Gaps = 5/67 (7%)

Query: 31 CGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIVSAWRPGTWASVA 90
          C  P  A+   +   PA  P P     + CPQ  +  P    L     + W PG+W  V 
Sbjct: 15 CLPPLPASAPTSPPNPATRPAPGPGRRARCPQSAHPAPTRGAL-----TFWAPGSWPRVL 69

Query: 91 SSLRLPG 97
             R PG
Sbjct: 70 LVPRSPG 76


>gi|23346412 cysteine-serine-rich nuclear protein 3 [Homo sapiens]
          Length = 585

 Score = 31.2 bits (69), Expect = 4.7
 Identities = 11/30 (36%), Positives = 19/30 (63%)

Query: 503 CEKRIDMVPELLSSNLCSLKCDVDRLAFSC 532
           C+ R+   P+  + +L  +KC VDR++F C
Sbjct: 214 CDCRVFCDPDTCTCSLAGIKCQVDRMSFPC 243


>gi|82617626 paralemmin 2 isoform b [Homo sapiens]
          Length = 379

 Score = 31.2 bits (69), Expect = 4.7
 Identities = 35/143 (24%), Positives = 59/143 (41%), Gaps = 9/143 (6%)

Query: 131 KKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPE-------LIDRLAC 183
           K+   D Q+ ++  +  +  +EK + +GIPA T EE       + E       L D +  
Sbjct: 29  KRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQR 88

Query: 184 LSEEGNEIES--GKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEE 241
           L +E   +ES   +I   E + L KL++  KS    Q  F ++        + +  D + 
Sbjct: 89  LEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQKGFSSTDGAVYAMEINVEKDKQT 148

Query: 242 NKEIILQGLKHLNRAVHEDIVAV 264
            +  IL         VH+  V V
Sbjct: 149 GETKILSTSTIGPEGVHQKGVKV 171


>gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens]
          Length = 5890

 Score = 31.2 bits (69), Expect = 4.7
 Identities = 25/100 (25%), Positives = 52/100 (52%), Gaps = 8/100 (8%)

Query: 827  KNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTVFHV-FDKVKV-KIMLD 884
            K  + V +PK  +EG +   + D   P++  D + P +++ D  +H+   K+K+ K  + 
Sbjct: 1668 KGDMDVSVPK--VEGEMKVPDVDIKGPKV--DIDAPDVEVHDPDWHLKMPKMKMPKFSMP 1723

Query: 885  SSNLQHQKIRMSLVEPQIP--GISIPTDTSNMDLNGPKKK 922
                +  ++ ++L +  I   G S+ TD  ++D+ GP+ K
Sbjct: 1724 GFKAEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGK 1763


>gi|124430557 a disintegrin-like and metalloprotease with
            thrombospondin type 1 motifs 20 [Homo sapiens]
          Length = 1910

 Score = 31.2 bits (69), Expect = 4.7
 Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 8/82 (9%)

Query: 37   AACGGAHEG-PALEPQPQDPASSVCPQPHYLLPDTNVLLHQIV--SAWRPGTWASVASSL 93
            AAC  AH   P+   QP    S+  P    L  + N ++H  V  + WR G W S +SS 
Sbjct: 1261 AACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGSCSSS- 1319

Query: 94   RLPGSLE---TYVEQEQGENAN 112
               G L+      + E G++A+
Sbjct: 1320 -CSGGLQHRAVVCQDENGQSAS 1340


>gi|28274682 zinc finger protein 33A isoform b [Homo sapiens]
          Length = 810

 Score = 31.2 bits (69), Expect = 4.7
 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 4/40 (10%)

Query: 125 WYNEHLKKMSADNQL----QVIFITNDRRNKEKAIEEGIP 160
           W  +HLK+ S +NQ     +V+FI N+   KE+    GIP
Sbjct: 85  WTADHLKERSQENQSKHLWEVVFINNEMLTKEQGDVIGIP 124


>gi|110347446 zinc finger protein 33A isoform a [Homo sapiens]
          Length = 811

 Score = 31.2 bits (69), Expect = 4.7
 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 4/40 (10%)

Query: 125 WYNEHLKKMSADNQL----QVIFITNDRRNKEKAIEEGIP 160
           W  +HLK+ S +NQ     +V+FI N+   KE+    GIP
Sbjct: 86  WTADHLKERSQENQSKHLWEVVFINNEMLTKEQGDVIGIP 125


>gi|24307875 zinc finger protein 33B [Homo sapiens]
          Length = 778

 Score = 31.2 bits (69), Expect = 4.7
 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 4/40 (10%)

Query: 125 WYNEHLKKMSADNQL----QVIFITNDRRNKEKAIEEGIP 160
           W  +HLK+ S +NQ     +V+FI N+   KE+    GIP
Sbjct: 86  WTADHLKERSQENQSKHLWEVVFINNEMLTKEQGNVIGIP 125


>gi|150010540 FERM domain containing 4B [Homo sapiens]
          Length = 1034

 Score = 30.8 bits (68), Expect = 6.1
 Identities = 15/47 (31%), Positives = 28/47 (59%)

Query: 264 VELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLK 310
           V L  KSQ++  S+  L   G  + +V +E++ E++L+    EK+L+
Sbjct: 392 VTLEAKSQFIMASNGSLISSGSQDSEVSEEQKREKILELKKKEKLLQ 438


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,745,609
Number of Sequences: 37866
Number of extensions: 1663740
Number of successful extensions: 6228
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 6143
Number of HSP's gapped (non-prelim): 61
length of query: 928
length of database: 18,247,518
effective HSP length: 112
effective length of query: 816
effective length of database: 14,006,526
effective search space: 11429325216
effective search space used: 11429325216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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