Guide to the Human Genome
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Search of human proteins with 189083732

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
         (456 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   929   0.0  
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   929   0.0  
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   929   0.0  
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   929   0.0  
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   929   0.0  
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   929   0.0  
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p...   929   0.0  
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s...   689   0.0  
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs...   689   0.0  
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr...   642   0.0  
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor...   639   0.0  
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs...   503   e-142
gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso...   487   e-137
gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform ...   378   e-105
gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform ...   373   e-103
gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso...   367   e-101
gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform...   357   2e-98
gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 ...   346   2e-95
gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon p...   298   9e-81
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]       275   5e-74
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]       275   5e-74
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]         275   5e-74
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]       275   6e-74
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso...   275   8e-74
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo...   271   1e-72
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo...   269   3e-72
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]       268   8e-72
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p...   267   1e-71
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is...   265   6e-71
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso...   265   6e-71

>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  929 bits (2402), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
           MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60

Query: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
           LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120

Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
           IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180

Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
           PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240

Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
           TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300

Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
           RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360

Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
           LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420

Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
           RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456


>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  929 bits (2402), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
           MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60

Query: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
           LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120

Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
           IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180

Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
           PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240

Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
           TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300

Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
           RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360

Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
           LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420

Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
           RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456


>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  929 bits (2402), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
           MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60

Query: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
           LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120

Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
           IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180

Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
           PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240

Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
           TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300

Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
           RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360

Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
           LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420

Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
           RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456


>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  929 bits (2402), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
           MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60

Query: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
           LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120

Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
           IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180

Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
           PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240

Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
           TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300

Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
           RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360

Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
           LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420

Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
           RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456


>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  929 bits (2402), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
           MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60

Query: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
           LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120

Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
           IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180

Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
           PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240

Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
           TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300

Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
           RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360

Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
           LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420

Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
           RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456


>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  929 bits (2402), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
           MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60

Query: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
           LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120

Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
           IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180

Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
           PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240

Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
           TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300

Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
           RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360

Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
           LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420

Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
           RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456


>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  929 bits (2402), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
           MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1   MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60

Query: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
           LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61  LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120

Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
           IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180

Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
           PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240

Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
           TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300

Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
           RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360

Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
           LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420

Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
           RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456


>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
           sapiens]
          Length = 451

 Score =  689 bits (1777), Expect = 0.0
 Identities = 340/418 (81%), Positives = 369/418 (88%), Gaps = 2/418 (0%)

Query: 32  QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDV 91
           +DE K+N T+FTRILDRLLDGYDNRLRPGLG+ +TEV T+I+VTSFGPVSD DMEYTIDV
Sbjct: 32  EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91

Query: 92  FFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITED 151
           FFRQ WKDERLKFKGPM +LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI +D
Sbjct: 92  FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151

Query: 152 GTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAED 211
           GTLLYTMRLTV+AECPMHLEDFPMDAH+CPLKFGSYAYT +EV Y WT   + SV VA D
Sbjct: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211

Query: 212 GSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
           GSRLNQYDLLGQ++    ++SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271

Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
           FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331

Query: 332 ATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
           ATVNYFTKRG+AWDGKSVV +K KK K  ++ +NN YA    +Y PNL++ DP L+TI+K
Sbjct: 332 ATVNYFTKRGWAWDGKSVVNDK-KKEKASVMIQNNAYAVAVANYAPNLSK-DPVLSTISK 389

Query: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQL 449
           SAT      KPE KP E KKTFNSVSKIDR+SRI FP+LFG FNLVYWATYLNREP L
Sbjct: 390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447


>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
           [Homo sapiens]
          Length = 451

 Score =  689 bits (1777), Expect = 0.0
 Identities = 340/418 (81%), Positives = 369/418 (88%), Gaps = 2/418 (0%)

Query: 32  QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDV 91
           +DE K+N T+FTRILDRLLDGYDNRLRPGLG+ +TEV T+I+VTSFGPVSD DMEYTIDV
Sbjct: 32  EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91

Query: 92  FFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITED 151
           FFRQ WKDERLKFKGPM +LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI +D
Sbjct: 92  FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151

Query: 152 GTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAED 211
           GTLLYTMRLTV+AECPMHLEDFPMDAH+CPLKFGSYAYT +EV Y WT   + SV VA D
Sbjct: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211

Query: 212 GSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
           GSRLNQYDLLGQ++    ++SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271

Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
           FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331

Query: 332 ATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
           ATVNYFTKRG+AWDGKSVV +K KK K  ++ +NN YA    +Y PNL++ DP L+TI+K
Sbjct: 332 ATVNYFTKRGWAWDGKSVVNDK-KKEKASVMIQNNAYAVAVANYAPNLSK-DPVLSTISK 389

Query: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQL 449
           SAT      KPE KP E KKTFNSVSKIDR+SRI FP+LFG FNLVYWATYLNREP L
Sbjct: 390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447


>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
           precursor [Homo sapiens]
          Length = 462

 Score =  642 bits (1656), Expect = 0.0
 Identities = 319/424 (75%), Positives = 358/424 (84%), Gaps = 7/424 (1%)

Query: 30  SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTI 89
           S++DE  DN T+FTRILD LLDGYDNRLRPGLGER+T+V+TDI+VTSFGPVSD +MEYTI
Sbjct: 37  SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTI 96

Query: 90  DVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIT 149
           DVFFRQSWKDERL+FKGPM  L LNNL+ASKIWTPDTFFHNGKKS+AHNMT PNKLLR+ 
Sbjct: 97  DVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLE 156

Query: 150 EDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVA 209
           +DGTLLYTMRLT+ AECPM LEDFPMDAHACPLKFGSYAY  +EVVY WT    +SVVVA
Sbjct: 157 DDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVA 216

Query: 210 EDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQ 269
           EDGSRLNQY L+GQTV +  + +STGEY +MT HFHLKRKIGYFVIQTYLPCIMTVILSQ
Sbjct: 217 EDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQ 276

Query: 270 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 329
           VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI
Sbjct: 277 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 336

Query: 330 EFATVNYFTKRGYAWDGKSVV-PEKPKKVKDPLIKKN-NTYAPTATSYTPNLARGDPGLA 387
           EFATVNYFTKRG+AWDGK  +   K KK ++ ++ K+ N +     S+ PN+    P   
Sbjct: 337 EFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNI----PKEQ 392

Query: 388 TIAKSATIEPKEVKP-ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
           T A ++      VKP E K  E KKT+NS+SKID++SRI FP+LFG FNLVYWATYLNRE
Sbjct: 393 TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNRE 452

Query: 447 PQLK 450
           P +K
Sbjct: 453 PVIK 456


>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
           [Homo sapiens]
          Length = 492

 Score =  639 bits (1648), Expect = 0.0
 Identities = 324/436 (74%), Positives = 357/436 (81%), Gaps = 17/436 (3%)

Query: 29  PSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYT 88
           P + D+  DN T+FTRILDRLLDGYDNRLRPGLG+ VTEVKTDI+VTSFGPVSD DMEYT
Sbjct: 54  PDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYT 113

Query: 89  IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI 148
           IDVFFRQ+W DERLKF GPM +L LNNL+ASKIWTPDTFFHNGKKSVAHNMT PNKLLR+
Sbjct: 114 IDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRL 173

Query: 149 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVV 208
            ++GTLLYTMRLT+ AECPMHLEDFPMD HACPLKFGSYAYT AEVVY WT    +SV V
Sbjct: 174 VDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEV 233

Query: 209 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 268
           A+DGSRLNQYDLLG  V + I++SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS
Sbjct: 234 AQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 293

Query: 269 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 328
           QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL
Sbjct: 294 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 353

Query: 329 IEFATVNYFTKRGYAWDGKSVVPE----KPKKVKDPLIKKNNTYAPTATSYTPNLARGDP 384
           IEFATVNYFTKR +AW+GK  VPE    K K    P  K + T+    T+Y  NLA+ D 
Sbjct: 354 IEFATVNYFTKRSWAWEGKK-VPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAK-DT 411

Query: 385 GLATIAKSAT----------IEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIF 434
             +TI+K A             PK    +  P E  KT+NSVSK+D++SRI FP+LF IF
Sbjct: 412 EFSTISKGAAPSASSTPTIIASPKATYVQDSPTE-TKTYNSVSKVDKISRIIFPVLFAIF 470

Query: 435 NLVYWATYLNREPQLK 450
           NLVYWATY+NRE  +K
Sbjct: 471 NLVYWATYVNRESAIK 486


>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
           [Homo sapiens]
          Length = 453

 Score =  503 bits (1295), Expect = e-142
 Identities = 258/418 (61%), Positives = 307/418 (73%), Gaps = 20/418 (4%)

Query: 43  TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
           +RILD LL+GYDNRLRPG G  VTEVKTDI+VTSFGPVSD +MEYT+DVFFRQ+W DERL
Sbjct: 33  SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92

Query: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
           KF GP  +L LNNLM SKIWTPDTFF NGKKS+AHNMT PNKL RI ++GT+LYTMRLT+
Sbjct: 93  KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152

Query: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222
            A+CPM L +FPMD HACPLKFGSYAY ++E++Y W + P  SV V E+ S L QYDL+G
Sbjct: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212

Query: 223 QTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
           QTV S  ++S+TGEYV+MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272

Query: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT---- 338
           TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT    
Sbjct: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQT 332

Query: 339 -----KRGYAWD-----GKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLAT 388
                K  +A        K+  P + + V  P  K +     T+ S  P ++  +     
Sbjct: 333 QKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLS-LPIVSSSEAN--- 388

Query: 389 IAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
             K  T  P        PP     F   SKID+ SRI FP+ F  FNLVYW  YL+++
Sbjct: 389 --KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKD 444


>gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor
           [Homo sapiens]
          Length = 554

 Score =  487 bits (1253), Expect = e-137
 Identities = 237/335 (70%), Positives = 281/335 (83%), Gaps = 3/335 (0%)

Query: 4   SPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGE 63
           S G+S  L  + L L+     S GQ   +++L   T  FTRILD LLDGYDNRLRPG G 
Sbjct: 13  SAGVSFALLRF-LCLAVCLNESPGQNQKEEKLC--TENFTRILDSLLDGYDNRLRPGFGG 69

Query: 64  RVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWT 123
            VTEVKTDI+VTSFGPVSD +MEYT+DVFFRQ+W D+RLK+ GP+ +LRLNN+M +K+WT
Sbjct: 70  PVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLNNMMVTKVWT 129

Query: 124 PDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLK 183
           PDTFF NGKKSV+HNMT PNKL RI  +GT+LYTMRLT+ AECPM L DFPMD HACPLK
Sbjct: 130 PDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLK 189

Query: 184 FGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTH 243
           FGSYAY ++E++Y WT+ P +SV V ++ S L QYDL+GQTV S  ++S TGEY+VMT +
Sbjct: 190 FGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVY 249

Query: 244 FHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNS 303
           FHL+RK+GYF+IQTY+PCIMTVILSQVSFW+N+ESVPARTVFG+TTVLTMTTLSISAR+S
Sbjct: 250 FHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHS 309

Query: 304 LPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT 338
           LPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 310 LPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFT 344



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 22/49 (44%), Positives = 32/49 (65%), Gaps = 1/49 (2%)

Query: 404 TKPPE-PKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKA 451
           T PP  P  + +  SKID+ +RI FP+ FG FN+VYW  YL+++   K+
Sbjct: 502 TPPPSAPPPSGSGTSKIDKYARILFPVTFGAFNMVYWVVYLSKDTMEKS 550


>gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform 1
           precursor [Homo sapiens]
          Length = 475

 Score =  378 bits (970), Expect = e-105
 Identities = 209/468 (44%), Positives = 288/468 (61%), Gaps = 38/468 (8%)

Query: 4   SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51
           +P  S  +  WILLL +L      Q S    +D   + T V T          IL+ LL+
Sbjct: 16  TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75

Query: 52  GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111
           GYDN+LRP +G + T + TD++V S GPV+  +MEYTID+FF Q+W D RLKF   + VL
Sbjct: 76  GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135

Query: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171
           RLN+ M  KIW PDTFF N KK+ AH +T PN++LRI  DG +LYT+RLT+ AEC + L 
Sbjct: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195

Query: 172 DFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIV 230
           +FPMD H+CPL+F SY Y R E+VY+W R    SV V +  S RL Q+  +G    + +V
Sbjct: 196 NFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVV 252

Query: 231 QSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 290
           ++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART  G+TTV
Sbjct: 253 KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312

Query: 291 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV 350
           LTMTTLS  AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF         +   
Sbjct: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV------SNRKPS 366

Query: 351 PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP- 402
            +K KK K+PL++  +  APT     P  A      AT  +          ++ K+    
Sbjct: 367 KDKDKKKKNPLLRMFSFKAPT-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 425

Query: 403 -------ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
                   T      +    ++K+D  +RI FP  F +FNLVYW +YL
Sbjct: 426 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 473


>gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform 2
           precursor [Homo sapiens]
          Length = 467

 Score =  373 bits (958), Expect = e-103
 Identities = 211/468 (45%), Positives = 284/468 (60%), Gaps = 46/468 (9%)

Query: 4   SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51
           +P  S  +  WILLL +L      Q S    +D   + T V T          IL+ LL+
Sbjct: 16  TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75

Query: 52  GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111
           GYDN+LRP +G + T + TD++V S GPV+  +MEYTID+FF Q+W D RLKF   + VL
Sbjct: 76  GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135

Query: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171
           RLN+ M  KIW PDTFF N KK+ AH +T PN++LRI  DG +LYT+RLT+ AEC + L 
Sbjct: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195

Query: 172 DFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIV 230
           +FPMD H+CPL+F SY Y R E+VY+W R    SV V +  S RL Q+  +G    + +V
Sbjct: 196 NFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVV 252

Query: 231 QSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 290
           ++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART  G+TTV
Sbjct: 253 KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312

Query: 291 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV 350
           LTMTTLS  AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF           V 
Sbjct: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYF-----------VS 361

Query: 351 PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP- 402
             KP K KD   KK    APT     P  A      AT  +          ++ K+    
Sbjct: 362 NRKPSKDKD---KKKKNPAPT-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 417

Query: 403 -------ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
                   T      +    ++K+D  +RI FP  F +FNLVYW +YL
Sbjct: 418 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465


>gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor
           [Homo sapiens]
          Length = 465

 Score =  367 bits (942), Expect = e-101
 Identities = 195/412 (47%), Positives = 256/412 (62%), Gaps = 24/412 (5%)

Query: 43  TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
           T+IL+ LL GYDN+LRP +G R T ++TD++V S GPV   +MEYTID+ F Q+W D RL
Sbjct: 65  TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124

Query: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
           KF   M VL LN+ M  KIW PDTFF N +KS AH +T PN+LLRI  DG +LYT+RLT+
Sbjct: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184

Query: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLL 221
            AEC + L +FPMD H+CPL+F SY Y + E+ Y+W +    SV VA+    RL Q+  +
Sbjct: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKP---SVEVADPKYWRLYQFAFV 241

Query: 222 GQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
           G    + I  + +G+YV+MT  F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301

Query: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
           RT  G+TTVLTMTTLS  AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT   
Sbjct: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN- 360

Query: 342 YAWDGKSVVPEKPKKVK----------DPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
               GK+   ++  K K            LI  NN   P    Y      G    +    
Sbjct: 361 --QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCC 418

Query: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
                       T      +    ++KID  SRI FP  F +FNLVYW  YL
Sbjct: 419 FEDC-------RTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463


>gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform 3
           precursor [Homo sapiens]
          Length = 515

 Score =  357 bits (915), Expect = 2e-98
 Identities = 208/508 (40%), Positives = 289/508 (56%), Gaps = 78/508 (15%)

Query: 4   SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51
           +P  S  +  WILLL +L      Q S    +D   + T V T          IL+ LL+
Sbjct: 16  TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75

Query: 52  GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111
           GYDN+LRP +G + T + TD++V S GPV+  +MEYTID+FF Q+W D RLKF   + VL
Sbjct: 76  GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135

Query: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171
           RLN+ M  KIW PDTFF N KK+ AH +T PN++LRI  DG +LYT+RLT+ AEC + L 
Sbjct: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195

Query: 172 DFPMDAHACPLKFGSYA----------------------------------------YTR 191
           +FPMD H+CPL+F S++                                        Y R
Sbjct: 196 NFPMDEHSCPLEFSSWSRSIAQAGMCSGVISAHYSLRFWGSTDPPTLASRVAGISDGYPR 255

Query: 192 AEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKI 250
            E+VY+W R    SV V +  S RL Q+  +G    + +V++++G+YVVM+ +F L R++
Sbjct: 256 EEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRM 312

Query: 251 GYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYA 310
           GYF IQTY+PC + V+LS VSFW+N+++VPART  G+TTVLTMTTLS  AR SLPKV+Y 
Sbjct: 313 GYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYV 372

Query: 311 TAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP 370
           TAMD F++VC+ FVFSAL+E+ T++YF         +    +K KK K+PL++  +  AP
Sbjct: 373 TAMDLFVSVCFIFVFSALVEYGTLHYFV------SNRKPSKDKDKKKKNPLLRMFSFKAP 426

Query: 371 TATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP--------ETKPPEPKKTFNS 415
           T     P  A      AT  +          ++ K+            T      +    
Sbjct: 427 T-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIR 485

Query: 416 VSKIDRLSRIAFPLLFGIFNLVYWATYL 443
           ++K+D  +RI FP  F +FNLVYW +YL
Sbjct: 486 IAKMDSYARIFFPTAFCLFNLVYWVSYL 513


>gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3
           [Homo sapiens]
          Length = 467

 Score =  346 bits (888), Expect = 2e-95
 Identities = 191/436 (43%), Positives = 258/436 (59%), Gaps = 39/436 (8%)

Query: 36  KDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQ 95
           K   T  T IL++LL  YD +LRP +G + T +  DI+V S GPVS  +MEY ID+FF Q
Sbjct: 41  KSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ 100

Query: 96  SWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLL 155
           +W D RL+F   M +L LN+ M   IW PDT F N K + AH +T PN+LLRI  DG +L
Sbjct: 101 TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL 160

Query: 156 YTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-R 214
           YT+RLT+ AEC + L +FPMD H+CPL F SY Y + E++Y W +    SV  A+  S R
Sbjct: 161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRK---NSVEAADQKSWR 217

Query: 215 LNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 274
           L Q+D +G    + IV +S G+YVVMT +F L R++GYF IQTY+PCI+TV+LS VSFW+
Sbjct: 218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWI 277

Query: 275 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV 334
            +++ PART  G+TTVLTMTTLS  AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+
Sbjct: 278 KKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337

Query: 335 NYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-----TATSYTPNLARGDPGLATI 389
           NY++            P   KK    L   ++ + P      A S    L    P  A I
Sbjct: 338 NYYS--------SCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMI 389

Query: 390 AKSATIEPKEVK--------------------PETKPPEPKK--TFNSVSKIDRLSRIAF 427
             + ++  +E +                     E K    +K      + ++D  SR+ F
Sbjct: 390 TLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFF 449

Query: 428 PLLFGIFNLVYWATYL 443
           P  F +FNLVYW  YL
Sbjct: 450 PTSFLLFNLVYWVGYL 465


>gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon
           precursor [Homo sapiens]
          Length = 506

 Score =  298 bits (762), Expect = 9e-81
 Identities = 164/446 (36%), Positives = 246/446 (55%), Gaps = 56/446 (12%)

Query: 43  TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
           +RIL+ +L  YD++LRPG+GE+ T V  +I V S GP+S  DMEYTID+ F Q+W DERL
Sbjct: 72  SRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERL 131

Query: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
            +      L LN  + S++W PDTFF N K++  H +TMPN+++RI +DG +LYT+R+T+
Sbjct: 132 CYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTI 191

Query: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222
            A C +H+  FPMD+H+CPL F S++Y   E++Y+W  E  +  +  ++  +L Q+D  G
Sbjct: 192 DAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKW--ENFKLEINEKNSWKLFQFDFTG 249

Query: 223 QTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
            +  + I+ +  G+++VMT  F++ R+ GY   Q Y+P  +T +LS VSFW+  ES PAR
Sbjct: 250 VSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPAR 309

Query: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGY 342
           T  G+T+VLTMTTL   +R + P+V+Y TA+D++IA+C+ F F AL+EFA +N+      
Sbjct: 310 TSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLIY--- 366

Query: 343 AWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPK--EV 400
                        K++ P I   N+ A   T             A + +  T E    E 
Sbjct: 367 ----NQTKAHASPKLRHPRI---NSRAHARTRARSRACARQHQEAFVCQIVTTEGSDGEE 419

Query: 401 KPE---TKPPEP----------------------KKTFNSVS-----------------K 418
           +P     +PP P                      KK F  V                  +
Sbjct: 420 RPSCSAQQPPSPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCIHVYR 479

Query: 419 IDRLSRIAFPLLFGIFNLVYWATYLN 444
           +D  SR+ FP+ F  FN++YW   LN
Sbjct: 480 LDNYSRVVFPVTFFFFNVLYWLVCLN 505


>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
          Length = 452

 Score =  275 bits (704), Expect = 5e-74
 Identities = 154/403 (38%), Positives = 234/403 (58%), Gaps = 15/403 (3%)

Query: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
           LD+L+    GYD R+RP        V  +IF+ SFG V++  M+Y +++F RQ W D RL
Sbjct: 48  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRL 107

Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
            +   P   L L+  M   IW PD FF N K +  H++T  NKLLRI+++G +LY++RLT
Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167

Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  +    V VAE G  L Q+ +L
Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223

Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
            +  + G      +TG++  +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ 
Sbjct: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283

Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ ++
Sbjct: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343

Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
           +   +       ++  K +D   +    ++     +   +  G     T  K+    P  
Sbjct: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398

Query: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
             P+      KK  +   +ID +SR AFPL F IFN+ YW TY
Sbjct: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441


>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
          Length = 449

 Score =  275 bits (704), Expect = 5e-74
 Identities = 161/404 (39%), Positives = 239/404 (59%), Gaps = 21/404 (5%)

Query: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
           LD+L+    GYD R+RP        V  +IF+ SFG +++  M+Y +++F RQ W D RL
Sbjct: 47  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106

Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
            +   P   L L+  M   IW PD FF N K +  H +T  NKLLRI ++G +LY++RLT
Sbjct: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166

Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  E    V VAE G  L Q+ LL
Sbjct: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222

Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
            +  D        +TG++  +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ 
Sbjct: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282

Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVFSAL+E+A VN+ ++
Sbjct: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342

Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
           +      + +   + +K KD  ++++  ++ TA    P L   D     +       P +
Sbjct: 343 Q----HKELLRFRRKRKNKDDEVRESR-FSFTAYGMGPCLQAKD----GMTPKGPNHPVQ 393

Query: 400 VKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
           V P++ P E +K F +   KID +SR  FPL F IFN+ YW  Y
Sbjct: 394 VMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436


>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
          Length = 452

 Score =  275 bits (704), Expect = 5e-74
 Identities = 154/403 (38%), Positives = 234/403 (58%), Gaps = 15/403 (3%)

Query: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
           LD+L+    GYD R+RP        V  +IF+ SFG V++  M+Y +++F RQ W D RL
Sbjct: 48  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRL 107

Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
            +   P   L L+  M   IW PD FF N K +  H++T  NKLLRI+++G +LY++RLT
Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167

Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  +    V VAE G  L Q+ +L
Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223

Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
            +  + G      +TG++  +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ 
Sbjct: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283

Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ ++
Sbjct: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343

Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
           +   +       ++  K +D   +    ++     +   +  G     T  K+    P  
Sbjct: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398

Query: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
             P+      KK  +   +ID +SR AFPL F IFN+ YW TY
Sbjct: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441


>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
          Length = 452

 Score =  275 bits (703), Expect = 6e-74
 Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)

Query: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
           LD+L+    GYD R+RP        V  +IF+ SFG +++  M+Y +++F RQ W D RL
Sbjct: 48  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107

Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
            +   P   L L+  M   IW PD FF N K +  H++T  NKLLRI+++G +LY++RLT
Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167

Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  +    V VAE G  L Q+ +L
Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223

Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
            +  + G      +TG++  +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ 
Sbjct: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283

Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ ++
Sbjct: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343

Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
           +   +       ++  K +D   +    ++     +   +  G     T  K+    P  
Sbjct: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398

Query: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
             P+      KK  +   +ID +SR AFPL F IFN+ YW TY
Sbjct: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441


>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
           isoform 2 [Homo sapiens]
          Length = 474

 Score =  275 bits (702), Expect = 8e-74
 Identities = 163/482 (33%), Positives = 250/482 (51%), Gaps = 67/482 (13%)

Query: 11  LWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKT 70
           +W++ L+++ +  +S   PS       N ++    +DRLL GYD RLRP  G     V  
Sbjct: 12  IWSFPLIIAAVCAQSVNDPS-------NMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGM 64

Query: 71  DIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHN 130
           +I + S   VS+ +M+YT+ ++F+Q+W+D+RL +      L L+N +A ++W PDT+F N
Sbjct: 65  NIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLN 124

Query: 131 GKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYT 190
            KKS  H +T+ N+++R+  DGT+LY +R+T  A C M L  +P+D   C L+  SY YT
Sbjct: 125 DKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYT 184

Query: 191 RAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKI 250
             ++ + W  +   + V       L Q+ ++   + +  V  STG Y  ++  F LKR I
Sbjct: 185 TDDIEFYWRGDD--NAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNI 242

Query: 251 GYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYA 310
           GYF++QTY+P I+  ILS VSFW+N ++  AR   G+TTVLTMTT++   R +LPK+ Y 
Sbjct: 243 GYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYV 302

Query: 311 TAMDWFIAVCYAFVFSALIEFATVNY-FTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYA 369
            A+D ++  C+ FVF AL+E+A VNY F  RG         P++ KK  +     NN   
Sbjct: 303 KAIDMYLMGCFVFVFMALLEYALVNYIFFGRG---------PQRQKKAAEKAASANNEKM 353

Query: 370 ----------------------PTATSYTPNLARGDPGLATIAKSAT------------- 394
                                   ATS    +  GDP    +A  A+             
Sbjct: 354 RLDVNKMDPHENILLSTLEIKNEMATSEAV-MGLGDPRSTMLAYDASSIQYRKAGLPRHS 412

Query: 395 ---------IEPKEVKPETKPPEPKKT---FNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
                    +  K+ +   +  + K T      V+ IDR SRI FP++F  FN+VYW  Y
Sbjct: 413 FGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472

Query: 443 LN 444
           +N
Sbjct: 473 VN 474


>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 457

 Score =  271 bits (692), Expect = 1e-72
 Identities = 156/415 (37%), Positives = 235/415 (56%), Gaps = 28/415 (6%)

Query: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
           LD+L+    GYD R+RP        V  +IF+ SFG +++  M+Y +++F RQ W D RL
Sbjct: 42  LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101

Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
            +   P   L L+  M   IW PD FF N K +  H +T  NKLLRI+ +G +LY++R+T
Sbjct: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161

Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  + A  V    DG  L Q+ +L
Sbjct: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217

Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
            +  D        +TG++  +   FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ 
Sbjct: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277

Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVFSAL+E+A VN+ ++
Sbjct: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337

Query: 340 RGYAWDGKSVV--PEKPKKVKDPLIK-------KNNTYAPTATSYTPNLARGDPGLAT-- 388
           +      K ++    K +  K P++            +  +A    P   +   G++   
Sbjct: 338 Q-----HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKG 392

Query: 389 IAKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
              S T  P    P   P E +K F     KID++SRI FP+ F IFN+ YW  Y
Sbjct: 393 ANNSNTTNPPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446


>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 449

 Score =  269 bits (688), Expect = 3e-72
 Identities = 154/407 (37%), Positives = 233/407 (57%), Gaps = 20/407 (4%)

Query: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
           LD+L+    GYD R+RP        V  +IF+ SFG +++  M+Y +++F RQ W D RL
Sbjct: 42  LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101

Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
            +   P   L L+  M   IW PD FF N K +  H +T  NKLLRI+ +G +LY++R+T
Sbjct: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161

Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  + A  V    DG  L Q+ +L
Sbjct: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217

Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
            +  D        +TG++  +   FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ 
Sbjct: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277

Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVFSAL+E+A VN+ ++
Sbjct: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337

Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKK-NNTYAPTATSYTPNLARGDPGLAT--IAKSATIE 396
           +      K ++  + K+      +     +  +A    P   +   G++      S T  
Sbjct: 338 Q-----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTN 392

Query: 397 PKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
           P    P   P E +K F     KID++SRI FP+ F IFN+ YW  Y
Sbjct: 393 PPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438


>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
          Length = 464

 Score =  268 bits (685), Expect = 8e-72
 Identities = 162/414 (39%), Positives = 237/414 (57%), Gaps = 26/414 (6%)

Query: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
           LD+L+    GYD R+RP        V  +IF+ SFG +++  M+Y +++F RQ W D RL
Sbjct: 47  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106

Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
            +   P   L L+  M   IW PD FF N K +  H +T  NKLLRI ++G +LY++RLT
Sbjct: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166

Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  E    V VAE G  L Q+ LL
Sbjct: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222

Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
            +  D        +TG++  +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ 
Sbjct: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282

Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT- 338
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVFSAL+E+A VN+ + 
Sbjct: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342

Query: 339 --------KRGYAWDGKSVVPEKPKKVKDPLIK-KNNTYAPTATSYTPNLARGDPGLATI 389
                   +R      ++   EK  +  D   + + + ++ TA    P L   D     +
Sbjct: 343 QHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKD----GM 398

Query: 390 AKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
                  P +V P++ P E +K F +   KID +SR  FPL F IFN+ YW  Y
Sbjct: 399 TPKGPNHPVQVMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451


>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
           precursor [Homo sapiens]
          Length = 474

 Score =  267 bits (683), Expect = 1e-71
 Identities = 165/472 (34%), Positives = 248/472 (52%), Gaps = 56/472 (11%)

Query: 15  ILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFV 74
           +++       S  +PS    +K+        +DRLL GYD RLRP  G    +V   I V
Sbjct: 17  VMITMVCCAHSTNEPSNMSYVKET-------VDRLLKGYDIRLRPDFGGPPVDVGMRIDV 69

Query: 75  TSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKS 134
            S   VS+ +M+YT+ ++F+QSWKD+RL + G    L L+N +A ++W PDT+F N KKS
Sbjct: 70  ASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKS 129

Query: 135 VAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEV 194
             H +T+ N+++R+  DGT+LY +R+T  A C M L  +P+D   C L+  SY YT  ++
Sbjct: 130 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 189

Query: 195 VYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFV 254
            + W        V   +   L Q+ ++   + S  V+ +TG Y  ++  F LKR IGYF+
Sbjct: 190 EFYW--NGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFI 247

Query: 255 IQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMD 314
           +QTY+P  +  ILS VSFW+N ++  AR   G+TTVLTMTT+S   R +LPK+ Y  A+D
Sbjct: 248 LQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAID 307

Query: 315 WFIAVCYAFVFSALIEFATVNYF------TKRGYAWDGKSVVPEKPK----KVK------ 358
            ++  C+ FVF AL+E+A VNY        K+G +   +S   EK K    KV+      
Sbjct: 308 IYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQS-ANEKNKLEMNKVQVDAHGN 366

Query: 359 ---DPLIKKNNTYA---------PTATSYT----------PNLARGDPGLAT----IAKS 392
                L  +N T           P AT Y+          P  +R   G A     +   
Sbjct: 367 ILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPSK 426

Query: 393 ATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLN 444
             I  +  + + K P+       V+ ID+ SR+ FP+ F +FN+VYW  Y++
Sbjct: 427 GRIRRRASQLKVKIPD----LTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH 474


>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
           isoform 2 precursor [Homo sapiens]
          Length = 473

 Score =  265 bits (677), Expect = 6e-71
 Identities = 158/445 (35%), Positives = 232/445 (52%), Gaps = 42/445 (9%)

Query: 38  NTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSW 97
           N +     +D+LL GYD RLRP  G     V  +I + S   VS+ +M+YT+ ++F+Q W
Sbjct: 33  NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92

Query: 98  KDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYT 157
           +D+RL + G    L L+N +A ++W PDT+F N KKS  H +T+ N+++R+  DGT+LY 
Sbjct: 93  RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152

Query: 158 MRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQ 217
           +R+T  A C M L  +P+D   C L+  SY YT  ++ + W        V   +   L Q
Sbjct: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--RGGDKAVTGVERIELPQ 210

Query: 218 YDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 277
           + ++   + S  V  +TG Y  ++  F LKR IGYF++QTY+P I+  ILS VSFW+N +
Sbjct: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270

Query: 278 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 336
           +  AR   G+TTVLTMTT++   R +LPK+ Y  A+D ++  C+ FVF AL+E+A VNY 
Sbjct: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330

Query: 337 FTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-------TATSYTPNLARGDPGLATI 389
           F  RG     K  + EK  K K+   K  +           T+      +     G+   
Sbjct: 331 FFGRGPQRQKK--LAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDT 388

Query: 390 AKSATIEPK---EVKPETKPPE------------PKKT---------------FNSVSKI 419
             SA        + + ++ P E             KKT                  V+ I
Sbjct: 389 RNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAI 448

Query: 420 DRLSRIAFPLLFGIFNLVYWATYLN 444
           DR SRI FP  F +FNLVYW  Y+N
Sbjct: 449 DRWSRIVFPFTFSLFNLVYWLYYVN 473


>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
           isoform 1 precursor [Homo sapiens]
          Length = 473

 Score =  265 bits (677), Expect = 6e-71
 Identities = 158/445 (35%), Positives = 232/445 (52%), Gaps = 42/445 (9%)

Query: 38  NTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSW 97
           N +     +D+LL GYD RLRP  G     V  +I + S   VS+ +M+YT+ ++F+Q W
Sbjct: 33  NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92

Query: 98  KDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYT 157
           +D+RL + G    L L+N +A ++W PDT+F N KKS  H +T+ N+++R+  DGT+LY 
Sbjct: 93  RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152

Query: 158 MRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQ 217
           +R+T  A C M L  +P+D   C L+  SY YT  ++ + W        V   +   L Q
Sbjct: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--RGGDKAVTGVERIELPQ 210

Query: 218 YDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 277
           + ++   + S  V  +TG Y  ++  F LKR IGYF++QTY+P I+  ILS VSFW+N +
Sbjct: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270

Query: 278 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 336
           +  AR   G+TTVLTMTT++   R +LPK+ Y  A+D ++  C+ FVF AL+E+A VNY 
Sbjct: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330

Query: 337 FTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-------TATSYTPNLARGDPGLATI 389
           F  RG     K  + EK  K K+   K  +           T+      +     G+   
Sbjct: 331 FFGRGPQRQKK--LAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDT 388

Query: 390 AKSATIEPK---EVKPETKPPE------------PKKT---------------FNSVSKI 419
             SA        + + ++ P E             KKT                  V+ I
Sbjct: 389 RNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAI 448

Query: 420 DRLSRIAFPLLFGIFNLVYWATYLN 444
           DR SRI FP  F +FNLVYW  Y+N
Sbjct: 449 DRWSRIVFPFTFSLFNLVYWLYYVN 473


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,151,710
Number of Sequences: 37866
Number of extensions: 715874
Number of successful extensions: 2044
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1858
Number of HSP's gapped (non-prelim): 155
length of query: 456
length of database: 18,247,518
effective HSP length: 106
effective length of query: 350
effective length of database: 14,233,722
effective search space: 4981802700
effective search space used: 4981802700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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