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Search of human proteins with 189083732
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
(456 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 929 0.0
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 929 0.0
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 929 0.0
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 929 0.0
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 929 0.0
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 929 0.0
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 929 0.0
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 689 0.0
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 689 0.0
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 642 0.0
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 639 0.0
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 503 e-142
gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso... 487 e-137
gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 378 e-105
gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 373 e-103
gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso... 367 e-101
gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform... 357 2e-98
gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 ... 346 2e-95
gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon p... 298 9e-81
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 275 5e-74
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 275 5e-74
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 275 5e-74
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 275 6e-74
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 275 8e-74
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 271 1e-72
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 269 3e-72
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 268 8e-72
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 267 1e-71
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 265 6e-71
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 265 6e-71
>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 929 bits (2402), Expect = 0.0
Identities = 456/456 (100%), Positives = 456/456 (100%)
Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 929 bits (2402), Expect = 0.0
Identities = 456/456 (100%), Positives = 456/456 (100%)
Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 929 bits (2402), Expect = 0.0
Identities = 456/456 (100%), Positives = 456/456 (100%)
Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 929 bits (2402), Expect = 0.0
Identities = 456/456 (100%), Positives = 456/456 (100%)
Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 929 bits (2402), Expect = 0.0
Identities = 456/456 (100%), Positives = 456/456 (100%)
Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 929 bits (2402), Expect = 0.0
Identities = 456/456 (100%), Positives = 456/456 (100%)
Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 929 bits (2402), Expect = 0.0
Identities = 456/456 (100%), Positives = 456/456 (100%)
Query: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG
Sbjct: 1 MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPG 60
Query: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK
Sbjct: 61 LGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASK 120
Query: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC
Sbjct: 121 IWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHAC 180
Query: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM
Sbjct: 181 PLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVM 240
Query: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
Sbjct: 241 TTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 300
Query: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP
Sbjct: 301 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDP 360
Query: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID
Sbjct: 361 LIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKID 420
Query: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Sbjct: 421 RLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 456
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 689 bits (1777), Expect = 0.0
Identities = 340/418 (81%), Positives = 369/418 (88%), Gaps = 2/418 (0%)
Query: 32 QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDV 91
+DE K+N T+FTRILDRLLDGYDNRLRPGLG+ +TEV T+I+VTSFGPVSD DMEYTIDV
Sbjct: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91
Query: 92 FFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITED 151
FFRQ WKDERLKFKGPM +LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI +D
Sbjct: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151
Query: 152 GTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAED 211
GTLLYTMRLTV+AECPMHLEDFPMDAH+CPLKFGSYAYT +EV Y WT + SV VA D
Sbjct: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211
Query: 212 GSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
GSRLNQYDLLGQ++ ++SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
Query: 332 ATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
ATVNYFTKRG+AWDGKSVV +K KK K ++ +NN YA +Y PNL++ DP L+TI+K
Sbjct: 332 ATVNYFTKRGWAWDGKSVVNDK-KKEKASVMIQNNAYAVAVANYAPNLSK-DPVLSTISK 389
Query: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQL 449
SAT KPE KP E KKTFNSVSKIDR+SRI FP+LFG FNLVYWATYLNREP L
Sbjct: 390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 689 bits (1777), Expect = 0.0
Identities = 340/418 (81%), Positives = 369/418 (88%), Gaps = 2/418 (0%)
Query: 32 QDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDV 91
+DE K+N T+FTRILDRLLDGYDNRLRPGLG+ +TEV T+I+VTSFGPVSD DMEYTIDV
Sbjct: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91
Query: 92 FFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITED 151
FFRQ WKDERLKFKGPM +LRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI +D
Sbjct: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151
Query: 152 GTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAED 211
GTLLYTMRLTV+AECPMHLEDFPMDAH+CPLKFGSYAYT +EV Y WT + SV VA D
Sbjct: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211
Query: 212 GSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
GSRLNQYDLLGQ++ ++SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
Query: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
Query: 332 ATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
ATVNYFTKRG+AWDGKSVV +K KK K ++ +NN YA +Y PNL++ DP L+TI+K
Sbjct: 332 ATVNYFTKRGWAWDGKSVVNDK-KKEKASVMIQNNAYAVAVANYAPNLSK-DPVLSTISK 389
Query: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQL 449
SAT KPE KP E KKTFNSVSKIDR+SRI FP+LFG FNLVYWATYLNREP L
Sbjct: 390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 642 bits (1656), Expect = 0.0
Identities = 319/424 (75%), Positives = 358/424 (84%), Gaps = 7/424 (1%)
Query: 30 SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTI 89
S++DE DN T+FTRILD LLDGYDNRLRPGLGER+T+V+TDI+VTSFGPVSD +MEYTI
Sbjct: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTI 96
Query: 90 DVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIT 149
DVFFRQSWKDERL+FKGPM L LNNL+ASKIWTPDTFFHNGKKS+AHNMT PNKLLR+
Sbjct: 97 DVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLE 156
Query: 150 EDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVA 209
+DGTLLYTMRLT+ AECPM LEDFPMDAHACPLKFGSYAY +EVVY WT +SVVVA
Sbjct: 157 DDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVA 216
Query: 210 EDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQ 269
EDGSRLNQY L+GQTV + + +STGEY +MT HFHLKRKIGYFVIQTYLPCIMTVILSQ
Sbjct: 217 EDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQ 276
Query: 270 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 329
VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI
Sbjct: 277 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 336
Query: 330 EFATVNYFTKRGYAWDGKSVV-PEKPKKVKDPLIKKN-NTYAPTATSYTPNLARGDPGLA 387
EFATVNYFTKRG+AWDGK + K KK ++ ++ K+ N + S+ PN+ P
Sbjct: 337 EFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNI----PKEQ 392
Query: 388 TIAKSATIEPKEVKP-ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
T A ++ VKP E K E KKT+NS+SKID++SRI FP+LFG FNLVYWATYLNRE
Sbjct: 393 TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNRE 452
Query: 447 PQLK 450
P +K
Sbjct: 453 PVIK 456
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 639 bits (1648), Expect = 0.0
Identities = 324/436 (74%), Positives = 357/436 (81%), Gaps = 17/436 (3%)
Query: 29 PSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYT 88
P + D+ DN T+FTRILDRLLDGYDNRLRPGLG+ VTEVKTDI+VTSFGPVSD DMEYT
Sbjct: 54 PDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYT 113
Query: 89 IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI 148
IDVFFRQ+W DERLKF GPM +L LNNL+ASKIWTPDTFFHNGKKSVAHNMT PNKLLR+
Sbjct: 114 IDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRL 173
Query: 149 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVV 208
++GTLLYTMRLT+ AECPMHLEDFPMD HACPLKFGSYAYT AEVVY WT +SV V
Sbjct: 174 VDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEV 233
Query: 209 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 268
A+DGSRLNQYDLLG V + I++SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS
Sbjct: 234 AQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 293
Query: 269 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 328
QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL
Sbjct: 294 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 353
Query: 329 IEFATVNYFTKRGYAWDGKSVVPE----KPKKVKDPLIKKNNTYAPTATSYTPNLARGDP 384
IEFATVNYFTKR +AW+GK VPE K K P K + T+ T+Y NLA+ D
Sbjct: 354 IEFATVNYFTKRSWAWEGKK-VPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAK-DT 411
Query: 385 GLATIAKSAT----------IEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIF 434
+TI+K A PK + P E KT+NSVSK+D++SRI FP+LF IF
Sbjct: 412 EFSTISKGAAPSASSTPTIIASPKATYVQDSPTE-TKTYNSVSKVDKISRIIFPVLFAIF 470
Query: 435 NLVYWATYLNREPQLK 450
NLVYWATY+NRE +K
Sbjct: 471 NLVYWATYVNRESAIK 486
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 503 bits (1295), Expect = e-142
Identities = 258/418 (61%), Positives = 307/418 (73%), Gaps = 20/418 (4%)
Query: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
+RILD LL+GYDNRLRPG G VTEVKTDI+VTSFGPVSD +MEYT+DVFFRQ+W DERL
Sbjct: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
Query: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
KF GP +L LNNLM SKIWTPDTFF NGKKS+AHNMT PNKL RI ++GT+LYTMRLT+
Sbjct: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
Query: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222
A+CPM L +FPMD HACPLKFGSYAY ++E++Y W + P SV V E+ S L QYDL+G
Sbjct: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
Query: 223 QTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
QTV S ++S+TGEYV+MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
Query: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT---- 338
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQT 332
Query: 339 -----KRGYAWD-----GKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLAT 388
K +A K+ P + + V P K + T+ S P ++ +
Sbjct: 333 QKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLS-LPIVSSSEAN--- 388
Query: 389 IAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
K T P PP F SKID+ SRI FP+ F FNLVYW YL+++
Sbjct: 389 --KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKD 444
>gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor
[Homo sapiens]
Length = 554
Score = 487 bits (1253), Expect = e-137
Identities = 237/335 (70%), Positives = 281/335 (83%), Gaps = 3/335 (0%)
Query: 4 SPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGE 63
S G+S L + L L+ S GQ +++L T FTRILD LLDGYDNRLRPG G
Sbjct: 13 SAGVSFALLRF-LCLAVCLNESPGQNQKEEKLC--TENFTRILDSLLDGYDNRLRPGFGG 69
Query: 64 RVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWT 123
VTEVKTDI+VTSFGPVSD +MEYT+DVFFRQ+W D+RLK+ GP+ +LRLNN+M +K+WT
Sbjct: 70 PVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLNNMMVTKVWT 129
Query: 124 PDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLK 183
PDTFF NGKKSV+HNMT PNKL RI +GT+LYTMRLT+ AECPM L DFPMD HACPLK
Sbjct: 130 PDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLK 189
Query: 184 FGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTH 243
FGSYAY ++E++Y WT+ P +SV V ++ S L QYDL+GQTV S ++S TGEY+VMT +
Sbjct: 190 FGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVY 249
Query: 244 FHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNS 303
FHL+RK+GYF+IQTY+PCIMTVILSQVSFW+N+ESVPARTVFG+TTVLTMTTLSISAR+S
Sbjct: 250 FHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHS 309
Query: 304 LPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT 338
LPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 310 LPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFT 344
Score = 49.7 bits (117), Expect = 6e-06
Identities = 22/49 (44%), Positives = 32/49 (65%), Gaps = 1/49 (2%)
Query: 404 TKPPE-PKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKA 451
T PP P + + SKID+ +RI FP+ FG FN+VYW YL+++ K+
Sbjct: 502 TPPPSAPPPSGSGTSKIDKYARILFPVTFGAFNMVYWVVYLSKDTMEKS 550
>gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform 1
precursor [Homo sapiens]
Length = 475
Score = 378 bits (970), Expect = e-105
Identities = 209/468 (44%), Positives = 288/468 (61%), Gaps = 38/468 (8%)
Query: 4 SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51
+P S + WILLL +L Q S +D + T V T IL+ LL+
Sbjct: 16 TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75
Query: 52 GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111
GYDN+LRP +G + T + TD++V S GPV+ +MEYTID+FF Q+W D RLKF + VL
Sbjct: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135
Query: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171
RLN+ M KIW PDTFF N KK+ AH +T PN++LRI DG +LYT+RLT+ AEC + L
Sbjct: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195
Query: 172 DFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIV 230
+FPMD H+CPL+F SY Y R E+VY+W R SV V + S RL Q+ +G + +V
Sbjct: 196 NFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVV 252
Query: 231 QSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 290
++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTV
Sbjct: 253 KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312
Query: 291 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV 350
LTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF +
Sbjct: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV------SNRKPS 366
Query: 351 PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP- 402
+K KK K+PL++ + APT P A AT + ++ K+
Sbjct: 367 KDKDKKKKNPLLRMFSFKAPT-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 425
Query: 403 -------ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
T + ++K+D +RI FP F +FNLVYW +YL
Sbjct: 426 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 473
>gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform 2
precursor [Homo sapiens]
Length = 467
Score = 373 bits (958), Expect = e-103
Identities = 211/468 (45%), Positives = 284/468 (60%), Gaps = 46/468 (9%)
Query: 4 SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51
+P S + WILLL +L Q S +D + T V T IL+ LL+
Sbjct: 16 TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75
Query: 52 GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111
GYDN+LRP +G + T + TD++V S GPV+ +MEYTID+FF Q+W D RLKF + VL
Sbjct: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135
Query: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171
RLN+ M KIW PDTFF N KK+ AH +T PN++LRI DG +LYT+RLT+ AEC + L
Sbjct: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195
Query: 172 DFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIV 230
+FPMD H+CPL+F SY Y R E+VY+W R SV V + S RL Q+ +G + +V
Sbjct: 196 NFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVV 252
Query: 231 QSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 290
++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTV
Sbjct: 253 KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312
Query: 291 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV 350
LTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF V
Sbjct: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYF-----------VS 361
Query: 351 PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP- 402
KP K KD KK APT P A AT + ++ K+
Sbjct: 362 NRKPSKDKD---KKKKNPAPT-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 417
Query: 403 -------ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
T + ++K+D +RI FP F +FNLVYW +YL
Sbjct: 418 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465
>gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor
[Homo sapiens]
Length = 465
Score = 367 bits (942), Expect = e-101
Identities = 195/412 (47%), Positives = 256/412 (62%), Gaps = 24/412 (5%)
Query: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
T+IL+ LL GYDN+LRP +G R T ++TD++V S GPV +MEYTID+ F Q+W D RL
Sbjct: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
Query: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
KF M VL LN+ M KIW PDTFF N +KS AH +T PN+LLRI DG +LYT+RLT+
Sbjct: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
Query: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLL 221
AEC + L +FPMD H+CPL+F SY Y + E+ Y+W + SV VA+ RL Q+ +
Sbjct: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKP---SVEVADPKYWRLYQFAFV 241
Query: 222 GQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
G + I + +G+YV+MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301
Query: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN- 360
Query: 342 YAWDGKSVVPEKPKKVK----------DPLIKKNNTYAPTATSYTPNLARGDPGLATIAK 391
GK+ ++ K K LI NN P Y G +
Sbjct: 361 --QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCC 418
Query: 392 SATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
T + ++KID SRI FP F +FNLVYW YL
Sbjct: 419 FEDC-------RTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
>gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform 3
precursor [Homo sapiens]
Length = 515
Score = 357 bits (915), Expect = 2e-98
Identities = 208/508 (40%), Positives = 289/508 (56%), Gaps = 78/508 (15%)
Query: 4 SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51
+P S + WILLL +L Q S +D + T V T IL+ LL+
Sbjct: 16 TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75
Query: 52 GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111
GYDN+LRP +G + T + TD++V S GPV+ +MEYTID+FF Q+W D RLKF + VL
Sbjct: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135
Query: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171
RLN+ M KIW PDTFF N KK+ AH +T PN++LRI DG +LYT+RLT+ AEC + L
Sbjct: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195
Query: 172 DFPMDAHACPLKFGSYA----------------------------------------YTR 191
+FPMD H+CPL+F S++ Y R
Sbjct: 196 NFPMDEHSCPLEFSSWSRSIAQAGMCSGVISAHYSLRFWGSTDPPTLASRVAGISDGYPR 255
Query: 192 AEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKI 250
E+VY+W R SV V + S RL Q+ +G + +V++++G+YVVM+ +F L R++
Sbjct: 256 EEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRM 312
Query: 251 GYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYA 310
GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTVLTMTTLS AR SLPKV+Y
Sbjct: 313 GYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYV 372
Query: 311 TAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP 370
TAMD F++VC+ FVFSAL+E+ T++YF + +K KK K+PL++ + AP
Sbjct: 373 TAMDLFVSVCFIFVFSALVEYGTLHYFV------SNRKPSKDKDKKKKNPLLRMFSFKAP 426
Query: 371 TATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP--------ETKPPEPKKTFNS 415
T P A AT + ++ K+ T +
Sbjct: 427 T-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIR 485
Query: 416 VSKIDRLSRIAFPLLFGIFNLVYWATYL 443
++K+D +RI FP F +FNLVYW +YL
Sbjct: 486 IAKMDSYARIFFPTAFCLFNLVYWVSYL 513
>gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3
[Homo sapiens]
Length = 467
Score = 346 bits (888), Expect = 2e-95
Identities = 191/436 (43%), Positives = 258/436 (59%), Gaps = 39/436 (8%)
Query: 36 KDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQ 95
K T T IL++LL YD +LRP +G + T + DI+V S GPVS +MEY ID+FF Q
Sbjct: 41 KSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ 100
Query: 96 SWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLL 155
+W D RL+F M +L LN+ M IW PDT F N K + AH +T PN+LLRI DG +L
Sbjct: 101 TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL 160
Query: 156 YTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-R 214
YT+RLT+ AEC + L +FPMD H+CPL F SY Y + E++Y W + SV A+ S R
Sbjct: 161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRK---NSVEAADQKSWR 217
Query: 215 LNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 274
L Q+D +G + IV +S G+YVVMT +F L R++GYF IQTY+PCI+TV+LS VSFW+
Sbjct: 218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWI 277
Query: 275 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV 334
+++ PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+
Sbjct: 278 KKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
Query: 335 NYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-----TATSYTPNLARGDPGLATI 389
NY++ P KK L ++ + P A S L P A I
Sbjct: 338 NYYS--------SCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMI 389
Query: 390 AKSATIEPKEVK--------------------PETKPPEPKK--TFNSVSKIDRLSRIAF 427
+ ++ +E + E K +K + ++D SR+ F
Sbjct: 390 TLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFF 449
Query: 428 PLLFGIFNLVYWATYL 443
P F +FNLVYW YL
Sbjct: 450 PTSFLLFNLVYWVGYL 465
>gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon
precursor [Homo sapiens]
Length = 506
Score = 298 bits (762), Expect = 9e-81
Identities = 164/446 (36%), Positives = 246/446 (55%), Gaps = 56/446 (12%)
Query: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
+RIL+ +L YD++LRPG+GE+ T V +I V S GP+S DMEYTID+ F Q+W DERL
Sbjct: 72 SRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERL 131
Query: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
+ L LN + S++W PDTFF N K++ H +TMPN+++RI +DG +LYT+R+T+
Sbjct: 132 CYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTI 191
Query: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222
A C +H+ FPMD+H+CPL F S++Y E++Y+W E + + ++ +L Q+D G
Sbjct: 192 DAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKW--ENFKLEINEKNSWKLFQFDFTG 249
Query: 223 QTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
+ + I+ + G+++VMT F++ R+ GY Q Y+P +T +LS VSFW+ ES PAR
Sbjct: 250 VSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPAR 309
Query: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGY 342
T G+T+VLTMTTL +R + P+V+Y TA+D++IA+C+ F F AL+EFA +N+
Sbjct: 310 TSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLIY--- 366
Query: 343 AWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPK--EV 400
K++ P I N+ A T A + + T E E
Sbjct: 367 ----NQTKAHASPKLRHPRI---NSRAHARTRARSRACARQHQEAFVCQIVTTEGSDGEE 419
Query: 401 KPE---TKPPEP----------------------KKTFNSVS-----------------K 418
+P +PP P KK F V +
Sbjct: 420 RPSCSAQQPPSPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCIHVYR 479
Query: 419 IDRLSRIAFPLLFGIFNLVYWATYLN 444
+D SR+ FP+ F FN++YW LN
Sbjct: 480 LDNYSRVVFPVTFFFFNVLYWLVCLN 505
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 275 bits (704), Expect = 5e-74
Identities = 154/403 (38%), Positives = 234/403 (58%), Gaps = 15/403 (3%)
Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
LD+L+ GYD R+RP V +IF+ SFG V++ M+Y +++F RQ W D RL
Sbjct: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRL 107
Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
+ P L L+ M IW PD FF N K + H++T NKLLRI+++G +LY++RLT
Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
+ CPM L++FPMD C ++ S+ YT ++++EW + V VAE G L Q+ +L
Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
+ + G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
+ + ++ K +D + ++ + + G T K+ P
Sbjct: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
Query: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
P+ KK + +ID +SR AFPL F IFN+ YW TY
Sbjct: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 275 bits (704), Expect = 5e-74
Identities = 161/404 (39%), Positives = 239/404 (59%), Gaps = 21/404 (5%)
Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
+ + + + +K KD ++++ ++ TA P L D + P +
Sbjct: 343 Q----HKELLRFRRKRKNKDDEVRESR-FSFTAYGMGPCLQAKD----GMTPKGPNHPVQ 393
Query: 400 VKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 394 VMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 275 bits (704), Expect = 5e-74
Identities = 154/403 (38%), Positives = 234/403 (58%), Gaps = 15/403 (3%)
Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
LD+L+ GYD R+RP V +IF+ SFG V++ M+Y +++F RQ W D RL
Sbjct: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRL 107
Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
+ P L L+ M IW PD FF N K + H++T NKLLRI+++G +LY++RLT
Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
+ CPM L++FPMD C ++ S+ YT ++++EW + V VAE G L Q+ +L
Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
+ + G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
+ + ++ K +D + ++ + + G T K+ P
Sbjct: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
Query: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
P+ KK + +ID +SR AFPL F IFN+ YW TY
Sbjct: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 275 bits (703), Expect = 6e-74
Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)
Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
+ P L L+ M IW PD FF N K + H++T NKLLRI+++G +LY++RLT
Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
+ CPM L++FPMD C ++ S+ YT ++++EW + V VAE G L Q+ +L
Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
+ + G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
+ + ++ K +D + ++ + + G T K+ P
Sbjct: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
Query: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
P+ KK + +ID +SR AFPL F IFN+ YW TY
Sbjct: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 275 bits (702), Expect = 8e-74
Identities = 163/482 (33%), Positives = 250/482 (51%), Gaps = 67/482 (13%)
Query: 11 LWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKT 70
+W++ L+++ + +S PS N ++ +DRLL GYD RLRP G V
Sbjct: 12 IWSFPLIIAAVCAQSVNDPS-------NMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGM 64
Query: 71 DIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHN 130
+I + S VS+ +M+YT+ ++F+Q+W+D+RL + L L+N +A ++W PDT+F N
Sbjct: 65 NIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLN 124
Query: 131 GKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYT 190
KKS H +T+ N+++R+ DGT+LY +R+T A C M L +P+D C L+ SY YT
Sbjct: 125 DKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYT 184
Query: 191 RAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKI 250
++ + W + + V L Q+ ++ + + V STG Y ++ F LKR I
Sbjct: 185 TDDIEFYWRGDD--NAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNI 242
Query: 251 GYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYA 310
GYF++QTY+P I+ ILS VSFW+N ++ AR G+TTVLTMTT++ R +LPK+ Y
Sbjct: 243 GYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYV 302
Query: 311 TAMDWFIAVCYAFVFSALIEFATVNY-FTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYA 369
A+D ++ C+ FVF AL+E+A VNY F RG P++ KK + NN
Sbjct: 303 KAIDMYLMGCFVFVFMALLEYALVNYIFFGRG---------PQRQKKAAEKAASANNEKM 353
Query: 370 ----------------------PTATSYTPNLARGDPGLATIAKSAT------------- 394
ATS + GDP +A A+
Sbjct: 354 RLDVNKMDPHENILLSTLEIKNEMATSEAV-MGLGDPRSTMLAYDASSIQYRKAGLPRHS 412
Query: 395 ---------IEPKEVKPETKPPEPKKT---FNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
+ K+ + + + K T V+ IDR SRI FP++F FN+VYW Y
Sbjct: 413 FGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472
Query: 443 LN 444
+N
Sbjct: 473 VN 474
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 271 bits (692), Expect = 1e-72
Identities = 156/415 (37%), Positives = 235/415 (56%), Gaps = 28/415 (6%)
Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
Query: 340 RGYAWDGKSVV--PEKPKKVKDPLIK-------KNNTYAPTATSYTPNLARGDPGLAT-- 388
+ K ++ K + K P++ + +A P + G++
Sbjct: 338 Q-----HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKG 392
Query: 389 IAKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
S T P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 393 ANNSNTTNPPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 449
Score = 269 bits (688), Expect = 3e-72
Identities = 154/407 (37%), Positives = 233/407 (57%), Gaps = 20/407 (4%)
Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
Query: 340 RGYAWDGKSVVPEKPKKVKDPLIKK-NNTYAPTATSYTPNLARGDPGLAT--IAKSATIE 396
+ K ++ + K+ + + +A P + G++ S T
Sbjct: 338 Q-----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTN 392
Query: 397 PKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 393 PPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 268 bits (685), Expect = 8e-72
Identities = 162/414 (39%), Positives = 237/414 (57%), Gaps = 26/414 (6%)
Query: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
Query: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
Query: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
Query: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
Query: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT- 338
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +
Sbjct: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
Query: 339 --------KRGYAWDGKSVVPEKPKKVKDPLIK-KNNTYAPTATSYTPNLARGDPGLATI 389
+R ++ EK + D + + + ++ TA P L D +
Sbjct: 343 QHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKD----GM 398
Query: 390 AKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
P +V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 399 TPKGPNHPVQVMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 267 bits (683), Expect = 1e-71
Identities = 165/472 (34%), Positives = 248/472 (52%), Gaps = 56/472 (11%)
Query: 15 ILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFV 74
+++ S +PS +K+ +DRLL GYD RLRP G +V I V
Sbjct: 17 VMITMVCCAHSTNEPSNMSYVKET-------VDRLLKGYDIRLRPDFGGPPVDVGMRIDV 69
Query: 75 TSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKS 134
S VS+ +M+YT+ ++F+QSWKD+RL + G L L+N +A ++W PDT+F N KKS
Sbjct: 70 ASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKS 129
Query: 135 VAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEV 194
H +T+ N+++R+ DGT+LY +R+T A C M L +P+D C L+ SY YT ++
Sbjct: 130 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 189
Query: 195 VYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFV 254
+ W V + L Q+ ++ + S V+ +TG Y ++ F LKR IGYF+
Sbjct: 190 EFYW--NGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFI 247
Query: 255 IQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMD 314
+QTY+P + ILS VSFW+N ++ AR G+TTVLTMTT+S R +LPK+ Y A+D
Sbjct: 248 LQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAID 307
Query: 315 WFIAVCYAFVFSALIEFATVNYF------TKRGYAWDGKSVVPEKPK----KVK------ 358
++ C+ FVF AL+E+A VNY K+G + +S EK K KV+
Sbjct: 308 IYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQS-ANEKNKLEMNKVQVDAHGN 366
Query: 359 ---DPLIKKNNTYA---------PTATSYT----------PNLARGDPGLAT----IAKS 392
L +N T P AT Y+ P +R G A +
Sbjct: 367 ILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPSK 426
Query: 393 ATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLN 444
I + + + K P+ V+ ID+ SR+ FP+ F +FN+VYW Y++
Sbjct: 427 GRIRRRASQLKVKIPD----LTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH 474
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 265 bits (677), Expect = 6e-71
Identities = 158/445 (35%), Positives = 232/445 (52%), Gaps = 42/445 (9%)
Query: 38 NTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSW 97
N + +D+LL GYD RLRP G V +I + S VS+ +M+YT+ ++F+Q W
Sbjct: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92
Query: 98 KDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYT 157
+D+RL + G L L+N +A ++W PDT+F N KKS H +T+ N+++R+ DGT+LY
Sbjct: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152
Query: 158 MRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQ 217
+R+T A C M L +P+D C L+ SY YT ++ + W V + L Q
Sbjct: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--RGGDKAVTGVERIELPQ 210
Query: 218 YDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 277
+ ++ + S V +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N +
Sbjct: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270
Query: 278 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 336
+ AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY
Sbjct: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330
Query: 337 FTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-------TATSYTPNLARGDPGLATI 389
F RG K + EK K K+ K + T+ + G+
Sbjct: 331 FFGRGPQRQKK--LAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDT 388
Query: 390 AKSATIEPK---EVKPETKPPE------------PKKT---------------FNSVSKI 419
SA + + ++ P E KKT V+ I
Sbjct: 389 RNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAI 448
Query: 420 DRLSRIAFPLLFGIFNLVYWATYLN 444
DR SRI FP F +FNLVYW Y+N
Sbjct: 449 DRWSRIVFPFTFSLFNLVYWLYYVN 473
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 265 bits (677), Expect = 6e-71
Identities = 158/445 (35%), Positives = 232/445 (52%), Gaps = 42/445 (9%)
Query: 38 NTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSW 97
N + +D+LL GYD RLRP G V +I + S VS+ +M+YT+ ++F+Q W
Sbjct: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92
Query: 98 KDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYT 157
+D+RL + G L L+N +A ++W PDT+F N KKS H +T+ N+++R+ DGT+LY
Sbjct: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152
Query: 158 MRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQ 217
+R+T A C M L +P+D C L+ SY YT ++ + W V + L Q
Sbjct: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--RGGDKAVTGVERIELPQ 210
Query: 218 YDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 277
+ ++ + S V +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N +
Sbjct: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270
Query: 278 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 336
+ AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY
Sbjct: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330
Query: 337 FTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-------TATSYTPNLARGDPGLATI 389
F RG K + EK K K+ K + T+ + G+
Sbjct: 331 FFGRGPQRQKK--LAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDT 388
Query: 390 AKSATIEPK---EVKPETKPPE------------PKKT---------------FNSVSKI 419
SA + + ++ P E KKT V+ I
Sbjct: 389 RNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAI 448
Query: 420 DRLSRIAFPLLFGIFNLVYWATYLN 444
DR SRI FP F +FNLVYW Y+N
Sbjct: 449 DRWSRIVFPFTFSLFNLVYWLYYVN 473
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,151,710
Number of Sequences: 37866
Number of extensions: 715874
Number of successful extensions: 2044
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1858
Number of HSP's gapped (non-prelim): 155
length of query: 456
length of database: 18,247,518
effective HSP length: 106
effective length of query: 350
effective length of database: 14,233,722
effective search space: 4981802700
effective search space used: 4981802700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.