Guide to the Human Genome
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Search of human proteins with 188219563

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|188219563 hypothetical protein LOC126731 [Homo sapiens]
         (270 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|188219563 hypothetical protein LOC126731 [Homo sapiens]            559   e-160
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    46   3e-05
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    46   3e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     45   7e-05
gi|23503317 coiled-coil domain containing 96 [Homo sapiens]            45   9e-05
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    44   1e-04
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ...    44   1e-04
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    43   3e-04
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    43   3e-04
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    43   3e-04
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    43   3e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        43   3e-04
gi|190684675 X-ray repair cross complementing protein 1 [Homo sa...    42   4e-04
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               42   4e-04
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           42   6e-04
gi|21389423 junctional sarcoplasmic reticulum protein 1 [Homo sa...    42   7e-04
gi|150378549 tangerin [Homo sapiens]                                   41   0.001
gi|30795231 brain abundant, membrane attached signal protein 1 [...    40   0.002
gi|153070260 myristoylated alanine-rich protein kinase C substra...    40   0.002
gi|157649073 adenylyl cyclase-associated protein [Homo sapiens]        40   0.002
gi|5453595 adenylyl cyclase-associated protein [Homo sapiens]          40   0.002
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    40   0.002
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    40   0.002
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    40   0.003
gi|147902746 MEX3A protein [Homo sapiens]                              40   0.003
gi|199559779 coiled-coil domain containing 8 [Homo sapiens]            39   0.004
gi|130502140 NEZHA isoform 2 [Homo sapiens]                            39   0.005
gi|122937255 NEZHA isoform 1 [Homo sapiens]                            39   0.005
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    39   0.005
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    39   0.005

>gi|188219563 hypothetical protein LOC126731 [Homo sapiens]
          Length = 270

 Score =  559 bits (1441), Expect = e-160
 Identities = 270/270 (100%), Positives = 270/270 (100%)

Query: 1   MSPGSGVKSEYMKRYQEPRWEEYGPCYRELLHYRLGRRLLEQAHAPWLWDDWGPAGSSED 60
           MSPGSGVKSEYMKRYQEPRWEEYGPCYRELLHYRLGRRLLEQAHAPWLWDDWGPAGSSED
Sbjct: 1   MSPGSGVKSEYMKRYQEPRWEEYGPCYRELLHYRLGRRLLEQAHAPWLWDDWGPAGSSED 60

Query: 61  SASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAA 120
           SASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAA
Sbjct: 61  SASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAA 120

Query: 121 LPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKEN 180
           LPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKEN
Sbjct: 121 LPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKEN 180

Query: 181 KHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHS 240
           KHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHS
Sbjct: 181 KHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHS 240

Query: 241 VDVEKNRKMKASSSENPWMTEYMRCYSARA 270
           VDVEKNRKMKASSSENPWMTEYMRCYSARA
Sbjct: 241 VDVEKNRKMKASSSENPWMTEYMRCYSARA 270


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 58  SEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAE 117
           +E + +SE++GA  P P    PS PPPV P  ++E E  A    EE + +   A  E A 
Sbjct: 777 TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAV 836

Query: 118 DAALPALPVKD--VEDKPEQQTRTRETDKSPTSTE 150
           D      PVK    E+  E   + ++ + +  + E
Sbjct: 837 DTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAE 871



 Score = 34.7 bits (78), Expect = 0.090
 Identities = 42/189 (22%), Positives = 77/189 (40%), Gaps = 28/189 (14%)

Query: 58  SEDSASSESSGAGGPAPRC---------APPSPPPPVEPA-TQEEAERRARGAPEEQDAE 107
           S  + +++ +G  GP P            PP+PPP   PA T+      A GAP    A 
Sbjct: 736 SPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAP 795

Query: 108 AGDA--------EAEDAEDAALPALPVKDVEDKPEQQTRTRETDKS--PTSTEPRQQPSA 157
              +        E ++ E AA P +   + +  P  +    +T K+  P  +E  ++   
Sbjct: 796 PSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEE 855

Query: 158 LFARG-NRKAVKSPQRSSSKIKENKHPFALYGWGEKQT--DTGSQKTHNVCASAPVHEIH 214
             A+G + +A ++    + K ++ +      G G   T   +G+ +  +  A+    E+ 
Sbjct: 856 GPAKGKDAEAAEATAEGALKAEKKEG-----GSGRATTAKSSGAPQDSDSSATCSADEVD 910

Query: 215 ESALRAKNR 223
           E+    KNR
Sbjct: 911 EAEGGDKNR 919



 Score = 29.3 bits (64), Expect = 3.8
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 7/56 (12%)

Query: 44   HAPWLWDDWGPAGSSEDSASSESSGAGGPAPRCAPPS---PPPPVEPATQEEAERR 96
            HAP     W P       +S  S G GG + R A  S      P+ P TQ+  ++R
Sbjct: 1814 HAPI----WRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQR 1865



 Score = 28.9 bits (63), Expect = 4.9
 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 11/88 (12%)

Query: 90  QEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTST 149
           Q++ +   R + EE+D +  + EAE  E+         +VE+  E   + +  D   TS 
Sbjct: 506 QQQQQPMPRSSQEEKDEKEKEKEAEKEEEK-------PEVENDKEDLLKEKTDD---TSG 555

Query: 150 EPRQQPSALFARGNRKAVKSPQRSSSKI 177
           E   +  A+ ++G RK   S  R   +I
Sbjct: 556 EDNDEKEAVASKG-RKTANSQGRRKGRI 582



 Score = 28.5 bits (62), Expect = 6.5
 Identities = 12/49 (24%), Positives = 24/49 (48%)

Query: 59   EDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAE 107
            ED+A ++ +    P P+   P    P +P +    + R+   P +++AE
Sbjct: 970  EDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAE 1018


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 58  SEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAE 117
           +E + +SE++GA  P P    PS PPPV P  ++E E  A    EE + +   A  E A 
Sbjct: 794 TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAV 853

Query: 118 DAALPALPVKD--VEDKPEQQTRTRETDKSPTSTE 150
           D      PVK    E+  E   + ++ + +  + E
Sbjct: 854 DTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAE 888



 Score = 34.7 bits (78), Expect = 0.090
 Identities = 42/189 (22%), Positives = 77/189 (40%), Gaps = 28/189 (14%)

Query: 58  SEDSASSESSGAGGPAPRC---------APPSPPPPVEPA-TQEEAERRARGAPEEQDAE 107
           S  + +++ +G  GP P            PP+PPP   PA T+      A GAP    A 
Sbjct: 753 SPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAP 812

Query: 108 AGDA--------EAEDAEDAALPALPVKDVEDKPEQQTRTRETDKS--PTSTEPRQQPSA 157
              +        E ++ E AA P +   + +  P  +    +T K+  P  +E  ++   
Sbjct: 813 PSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEE 872

Query: 158 LFARG-NRKAVKSPQRSSSKIKENKHPFALYGWGEKQT--DTGSQKTHNVCASAPVHEIH 214
             A+G + +A ++    + K ++ +      G G   T   +G+ +  +  A+    E+ 
Sbjct: 873 GPAKGKDAEAAEATAEGALKAEKKEG-----GSGRATTAKSSGAPQDSDSSATCSADEVD 927

Query: 215 ESALRAKNR 223
           E+    KNR
Sbjct: 928 EAEGGDKNR 936



 Score = 29.3 bits (64), Expect = 3.8
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 7/56 (12%)

Query: 44   HAPWLWDDWGPAGSSEDSASSESSGAGGPAPRCAPPS---PPPPVEPATQEEAERR 96
            HAP     W P       +S  S G GG + R A  S      P+ P TQ+  ++R
Sbjct: 1830 HAPI----WRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQR 1881



 Score = 28.9 bits (63), Expect = 4.9
 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 11/88 (12%)

Query: 90  QEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTST 149
           Q++ +   R + EE+D +  + EAE  E+         +VE+  E   + +  D   TS 
Sbjct: 506 QQQQQPMPRSSQEEKDEKEKEKEAEKEEEK-------PEVENDKEDLLKEKTDD---TSG 555

Query: 150 EPRQQPSALFARGNRKAVKSPQRSSSKI 177
           E   +  A+ ++G RK   S  R   +I
Sbjct: 556 EDNDEKEAVASKG-RKTANSQGRRKGRI 582



 Score = 28.5 bits (62), Expect = 6.5
 Identities = 12/49 (24%), Positives = 24/49 (48%)

Query: 59   EDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAE 107
            ED+A ++ +    P P+   P    P +P +    + R+   P +++AE
Sbjct: 986  EDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAE 1034


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 49/202 (24%), Positives = 84/202 (41%), Gaps = 19/202 (9%)

Query: 56  GSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAED 115
           G  E++ S  +  A  P      P          +EEA+  A     E++     AE + 
Sbjct: 496 GGEEETKSPPAEEAASPEKEAKSP---------VKEEAKSPAEAKSPEKEEAKSPAEVKS 546

Query: 116 AEDAALPALPVKDVEDKPEQQTRTRETDKSPT---STEPRQQPSALFARGNRKAVKSPQR 172
            E A  PA   ++ +  PE ++  +E  KSP    S E  + P+   A+   +A KSP++
Sbjct: 547 PEKAKSPA--KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA-KSPEK 603

Query: 173 SSSKIKEN-KHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKRKL 231
           + S +KE  K P       +++  + ++      A +P  E  +S  +AK+    EK + 
Sbjct: 604 AKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS---PEKEEA 660

Query: 232 VAQRQRAHSVDVEKNRKMKASS 253
            +  +    V  E     KA S
Sbjct: 661 KSPEKAKSPVKAEAKSPEKAKS 682



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 53/222 (23%), Positives = 95/222 (42%), Gaps = 29/222 (13%)

Query: 55  AGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAE----RRARGAPEEQDAEAGD 110
           A S  ++ S E   A  PA   +P     P +   +  AE     +A+   +E+     +
Sbjct: 558 AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617

Query: 111 AEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSP---TSTEPRQQPSALFARGNRKA- 166
           A++   E+A  PA    +V+   + ++ T+E  KSP    S E  +  S   A+   KA 
Sbjct: 618 AKSPVKEEAKSPA----EVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAE 673

Query: 167 VKSPQRSSSKIK-ENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKN--- 222
            KSP+++ S +K E K P       + ++    +      A +PV E  +S  +AK+   
Sbjct: 674 AKSPEKAKSPVKAEAKSP------EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727

Query: 223 --RRQVEKRKLVAQR-----QRAHSVDVEKNRKMKASSSENP 257
              +  EK K   +      ++A S +  K   +K+  ++ P
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP 769



 Score = 37.7 bits (86), Expect = 0.011
 Identities = 47/187 (25%), Positives = 82/187 (43%), Gaps = 19/187 (10%)

Query: 86  EPATQEEAERRARGAPEEQDAEAGDAEAED-------AEDAALP----ALPVKDVEDKP- 133
           E   +EE E +     EE+  E  +AE  +       AE+AA P      PVK+    P 
Sbjct: 469 EVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPA 528

Query: 134 EQQTRTRETDKSPT---STEPRQQPSALFARGNRKAVKSPQRSSSKI-KENKHPFALYGW 189
           E ++  +E  KSP    S E  + P+   A+   +A KSP++  +K   E K P      
Sbjct: 529 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA-KSPEKEEAKSPAEVKSPEKAKSP 587

Query: 190 GEKQTDTGSQKTHNVCASAPVHEIHESALRAKN--RRQVEKRKLVAQRQRAHSVDVEKNR 247
            +++  + ++      A +PV E  +S   AK+  + + +    V   ++A S   E+ +
Sbjct: 588 AKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAK 647

Query: 248 KMKASSS 254
             + + S
Sbjct: 648 SPEKAKS 654



 Score = 35.8 bits (81), Expect = 0.040
 Identities = 40/169 (23%), Positives = 71/169 (42%), Gaps = 11/169 (6%)

Query: 89  TQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPA-LPVKDVEDKPEQQTRT--RETDKS 145
           T+E  E   + A EE+  E    E E+AE        P  +    PE++ ++  +E  KS
Sbjct: 467 TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS 526

Query: 146 PTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKEN-KHPFALYGWGEKQTDTGSQKTHNV 204
           P   +  ++  A     +   VKSP+++ S  KE  K P       +++  + ++     
Sbjct: 527 PAEAKSPEKEEA----KSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPE 582

Query: 205 CASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASS 253
            A +P  E  +S   AK+    EK K   + +     + +   K +A S
Sbjct: 583 KAKSPAKEEAKSPAEAKS---PEKAKSPVKEEAKSPAEAKSPVKEEAKS 628



 Score = 35.4 bits (80), Expect = 0.053
 Identities = 39/175 (22%), Positives = 62/175 (35%), Gaps = 23/175 (13%)

Query: 87  PATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSP 146
           P  +  A+  AR   ++   +A     E+ +       P+K+    PE++   +E  KSP
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823

Query: 147 TSTEPRQQPSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCA 206
              E + Q            VK P +   K +E K P          T    +K  +   
Sbjct: 824 VKEEEKPQ---------EVKVKEPPK---KAEEEKAP---------ATPKTEEKKDSKKE 862

Query: 207 SAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASSSENPWMTE 261
            AP  E  +  +  K    VEK K    +  A   + E  +K+     E P   E
Sbjct: 863 EAPKKEAPKPKVEEKKEPAVEKPK--ESKVEAKKEEAEDKKKVPTPEKEAPAKVE 915



 Score = 34.3 bits (77), Expect = 0.12
 Identities = 36/139 (25%), Positives = 58/139 (41%), Gaps = 18/139 (12%)

Query: 55  AGSSEDSASSESSGAGGPAPRCAPP---SP-------PPPVEPATQEEAERRARGAPEEQ 104
           A S  ++ S E   A  PA   +P    SP       PP  +   +EEA+  A     E+
Sbjct: 524 AKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEK 583

Query: 105 DAEAGDAEAEDAEDAALPAL---PVKDVEDKP-EQQTRTRETDKSPTSTEPRQQPSALFA 160
                  EA+   +A  P     PVK+    P E ++  +E  KSP   +  ++  +   
Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS--- 640

Query: 161 RGNRKAVKSPQRSSSKIKE 179
              ++  KSP+++ S  KE
Sbjct: 641 -PTKEEAKSPEKAKSPEKE 658



 Score = 33.5 bits (75), Expect = 0.20
 Identities = 35/165 (21%), Positives = 67/165 (40%), Gaps = 14/165 (8%)

Query: 82  PPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRE 141
           P   +   +E+A+   +  P++++ ++   E E  ++  +   P K  E+K     +T E
Sbjct: 796 PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEE 855

Query: 142 TDKSPTSTEPRQQ-PSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQK 200
              S     P+++ P          AV+ P+ S  + K+           E+  D     
Sbjct: 856 KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKK-----------EEAEDKKKVP 904

Query: 201 THNVCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEK 245
           T    A A V E+ E A + K + +V K++    + +  S   EK
Sbjct: 905 TPEKEAPAKV-EVKEDA-KPKEKTEVAKKEPDDAKAKEPSKPAEK 947



 Score = 32.7 bits (73), Expect = 0.34
 Identities = 29/112 (25%), Positives = 47/112 (41%), Gaps = 7/112 (6%)

Query: 72   PAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVED 131
            P P    P+     E A  +E    A+  P++  A+     AE  E A       ++   
Sbjct: 904  PTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAK 963

Query: 132  KPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKENKHP 183
            KPE++ +T    K    T  + +PS        KA K+ + SS+  K++K P
Sbjct: 964  KPEEKPKTEAKAKEDDKTLSK-EPS------KPKAEKAEKSSSTDQKDSKPP 1008


>gi|23503317 coiled-coil domain containing 96 [Homo sapiens]
          Length = 555

 Score = 44.7 bits (104), Expect = 9e-05
 Identities = 43/180 (23%), Positives = 66/180 (36%), Gaps = 14/180 (7%)

Query: 54  PAGSSEDSASSESSGAGGPAPRCAP-PSPPPPVEPATQEEAERRARGAPEEQDAEAGDAE 112
           P G +   A+ E  G G P     P P P  P E   +E A+      PEE +AEAG  E
Sbjct: 70  PKGLTAAEAAGEE-GPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEE 128

Query: 113 AEDAED-------AALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRK 165
            E A +       A+LP   + + E     +  T   +      E  Q+  A     + +
Sbjct: 129 LEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAETERVEGEEEDKEETQRDGAESKERDGE 188

Query: 166 AVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQ 225
              +  +   K    +  F    W E+      QK       + + + + S L  +NR Q
Sbjct: 189 GRPAKSQEEGKRLYGRDEFEDLEWSEE-----VQKLQEQQLRSDLLDQYRSLLVERNRSQ 243



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 4/122 (3%)

Query: 50  DDWGPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARG---APEEQDA 106
           D  G  G  E  A+  S       P  +P       EP  +EE +  ++G   A E+ +A
Sbjct: 10  DPGGEGGDGESLAARPSKIKASSGPPTSPEPGELESEPEEEEEEQAASQGGTAADEQAEA 69

Query: 107 EAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKA 166
             G   AE A +   P  P +  E +PE +       + P   EP   P  L A    + 
Sbjct: 70  PKGLTAAEAAGEEG-PGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEE 128

Query: 167 VK 168
           ++
Sbjct: 129 LE 130


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
          Length = 1341

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 49/187 (26%), Positives = 79/187 (42%), Gaps = 34/187 (18%)

Query: 74   PRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKP 133
            PR   P PPPPV+P     AE+R      EQ+    +  AE            ++ E + 
Sbjct: 1114 PRPLHPPPPPPVQPPQHPRAEQR------EQERAVREQWAE------------REREMER 1155

Query: 134  EQQTRT-RETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEK 192
             ++TR+ RE D+      PR +  +   R   +A    ++S  K K  + P A      K
Sbjct: 1156 RERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPA------K 1209

Query: 193  QTDTGSQKTH--------NVCASAPVHEIHESALRAKNRRQVEK-RKLVAQRQRAHSVDV 243
              D   +KT          +  S  V +  E A RAK R +  K ++   Q++R    + 
Sbjct: 1210 LLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAER 1269

Query: 244  EKNRKMK 250
            E+NR+++
Sbjct: 1270 ERNRQLE 1276



 Score = 29.3 bits (64), Expect = 3.8
 Identities = 19/75 (25%), Positives = 30/75 (40%), Gaps = 10/75 (13%)

Query: 81  PPPPVEPATQE-------EAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDV---E 130
           PP   +P T E       E+ER      E+++     +E     D   P +P+ D    +
Sbjct: 740 PPAATQPQTSETQTSHLPESERIHHTVEEKEEVTMDTSENRPENDVPEPPMPIADQVSND 799

Query: 131 DKPEQQTRTRETDKS 145
           D+PE      E  +S
Sbjct: 800 DRPEGSVEDEEKKES 814


>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
           sapiens]
          Length = 1119

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 40/150 (26%), Positives = 52/150 (34%), Gaps = 22/150 (14%)

Query: 55  AGSSEDSASSESSGAGGPAPRCAP-PSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113
           AG +   A     G   P P   P P P  P EP  Q + ER        Q  EAG AE 
Sbjct: 636 AGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEM 695

Query: 114 EDAE-----------------DAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPS 156
            D                   D     L V + + K   Q R  + +  P   E  Q+P 
Sbjct: 696 LDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQEDEEDKPRQVEVHQEPG 755

Query: 157 ALFARGNRKAVKSPQRSSSKIKENKHPFAL 186
           A   RG     ++P+  + +  EN  P  L
Sbjct: 756 AAVPRGQ----EAPEGKARETVENLPPLPL 781



 Score = 28.5 bits (62), Expect = 6.5
 Identities = 31/115 (26%), Positives = 41/115 (35%), Gaps = 18/115 (15%)

Query: 66  SSGAGGPAP----RCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAAL 121
           S  AGG AP    + APP P    E    E+ E   R    +   EAGD   ED +    
Sbjct: 524 SRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDL-PEDPQ---- 578

Query: 122 PALPVKDVEDKPEQQTRTRETDKSPTSTEPR------QQPSALFARGNRKAVKSP 170
               V + + +P  Q    +         PR      +Q + L   G  KA   P
Sbjct: 579 ---KVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGP 630


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 39/137 (28%), Positives = 59/137 (43%), Gaps = 19/137 (13%)

Query: 56   GSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAER----RARGAPEEQDAEAGDA 111
            G  ED+ASSE   A  PA     P      EP  +EE E+      +   EE+  E  + 
Sbjct: 1239 GEEEDAASSEVPAAS-PADSSNSPETETK-EPEVEEEEEKPRVSEEQRQSEEEQQELEEP 1296

Query: 112  EAEDAEDAALPALP-----VKDVEDKPEQQTRTRETDKSPTSTEPRQQPSA--LFARGNR 164
            E E+ EDAA            D +D   + T+ +E ++ PT  + +++P     F   N 
Sbjct: 1297 EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANM 1356

Query: 165  KAVKSPQRSSSKIKENK 181
                  Q+S  KIK+ +
Sbjct: 1357 ------QKSREKIKDKE 1367



 Score = 35.0 bits (79), Expect = 0.069
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 10/79 (12%)

Query: 79   PSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTR 138
            P    P+    +EE E +A    E ++AE G  E EDA  + +PA    D  + PE +T+
Sbjct: 1213 PKEDMPLPEERKEEEEMQA----EAEEAEEG--EEEDAASSEVPAASPADSSNSPETETK 1266

Query: 139  ----TRETDKSPTSTEPRQ 153
                  E +K   S E RQ
Sbjct: 1267 EPEVEEEEEKPRVSEEQRQ 1285



 Score = 28.5 bits (62), Expect = 6.5
 Identities = 33/164 (20%), Positives = 63/164 (38%), Gaps = 13/164 (7%)

Query: 102 EEQDAEAGDAEAEDAEDAALPALPVKDV-EDKPEQQTRTRETDKSPTSTEP---RQQPSA 157
           EE++AE G+ E    ++  L     K V  +  EQ + + E++K P    P    +    
Sbjct: 790 EEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQ 849

Query: 158 LFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESA 217
           +    +  A   P R     ++N+     +G      D  S+      +SAP  +  E  
Sbjct: 850 VLPHDSLPANSQPSRRGRWGRKNRKTQERFG------DKDSKLLLEETSSAPQEQYGECG 903

Query: 218 LRAKNRRQ---VEKRKLVAQRQRAHSVDVEKNRKMKASSSENPW 258
            +++  ++     + +LVA  ++          K + S    PW
Sbjct: 904 EKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPW 947


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 39/137 (28%), Positives = 59/137 (43%), Gaps = 19/137 (13%)

Query: 56   GSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAER----RARGAPEEQDAEAGDA 111
            G  ED+ASSE   A  PA     P      EP  +EE E+      +   EE+  E  + 
Sbjct: 1239 GEEEDAASSEVPAAS-PADSSNSPETETK-EPEVEEEEEKPRVSEEQRQSEEEQQELEEP 1296

Query: 112  EAEDAEDAALPALP-----VKDVEDKPEQQTRTRETDKSPTSTEPRQQPSA--LFARGNR 164
            E E+ EDAA            D +D   + T+ +E ++ PT  + +++P     F   N 
Sbjct: 1297 EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANM 1356

Query: 165  KAVKSPQRSSSKIKENK 181
                  Q+S  KIK+ +
Sbjct: 1357 ------QKSREKIKDKE 1367



 Score = 35.0 bits (79), Expect = 0.069
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 10/79 (12%)

Query: 79   PSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTR 138
            P    P+    +EE E +A    E ++AE G  E EDA  + +PA    D  + PE +T+
Sbjct: 1213 PKEDMPLPEERKEEEEMQA----EAEEAEEG--EEEDAASSEVPAASPADSSNSPETETK 1266

Query: 139  ----TRETDKSPTSTEPRQ 153
                  E +K   S E RQ
Sbjct: 1267 EPEVEEEEEKPRVSEEQRQ 1285



 Score = 28.5 bits (62), Expect = 6.5
 Identities = 33/164 (20%), Positives = 63/164 (38%), Gaps = 13/164 (7%)

Query: 102 EEQDAEAGDAEAEDAEDAALPALPVKDV-EDKPEQQTRTRETDKSPTSTEP---RQQPSA 157
           EE++AE G+ E    ++  L     K V  +  EQ + + E++K P    P    +    
Sbjct: 790 EEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQ 849

Query: 158 LFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESA 217
           +    +  A   P R     ++N+     +G      D  S+      +SAP  +  E  
Sbjct: 850 VLPHDSLPANSQPSRRGRWGRKNRKTQERFG------DKDSKLLLEETSSAPQEQYGECG 903

Query: 218 LRAKNRRQ---VEKRKLVAQRQRAHSVDVEKNRKMKASSSENPW 258
            +++  ++     + +LVA  ++          K + S    PW
Sbjct: 904 EKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPW 947


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 39/137 (28%), Positives = 59/137 (43%), Gaps = 19/137 (13%)

Query: 56   GSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAER----RARGAPEEQDAEAGDA 111
            G  ED+ASSE   A  PA     P      EP  +EE E+      +   EE+  E  + 
Sbjct: 1239 GEEEDAASSEVPAAS-PADSSNSPETETK-EPEVEEEEEKPRVSEEQRQSEEEQQELEEP 1296

Query: 112  EAEDAEDAALPALP-----VKDVEDKPEQQTRTRETDKSPTSTEPRQQPSA--LFARGNR 164
            E E+ EDAA            D +D   + T+ +E ++ PT  + +++P     F   N 
Sbjct: 1297 EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANM 1356

Query: 165  KAVKSPQRSSSKIKENK 181
                  Q+S  KIK+ +
Sbjct: 1357 ------QKSREKIKDKE 1367



 Score = 35.0 bits (79), Expect = 0.069
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 10/79 (12%)

Query: 79   PSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTR 138
            P    P+    +EE E +A    E ++AE G  E EDA  + +PA    D  + PE +T+
Sbjct: 1213 PKEDMPLPEERKEEEEMQA----EAEEAEEG--EEEDAASSEVPAASPADSSNSPETETK 1266

Query: 139  ----TRETDKSPTSTEPRQ 153
                  E +K   S E RQ
Sbjct: 1267 EPEVEEEEEKPRVSEEQRQ 1285



 Score = 28.5 bits (62), Expect = 6.5
 Identities = 33/164 (20%), Positives = 63/164 (38%), Gaps = 13/164 (7%)

Query: 102 EEQDAEAGDAEAEDAEDAALPALPVKDV-EDKPEQQTRTRETDKSPTSTEP---RQQPSA 157
           EE++AE G+ E    ++  L     K V  +  EQ + + E++K P    P    +    
Sbjct: 790 EEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQ 849

Query: 158 LFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESA 217
           +    +  A   P R     ++N+     +G      D  S+      +SAP  +  E  
Sbjct: 850 VLPHDSLPANSQPSRRGRWGRKNRKTQERFG------DKDSKLLLEETSSAPQEQYGECG 903

Query: 218 LRAKNRRQ---VEKRKLVAQRQRAHSVDVEKNRKMKASSSENPW 258
            +++  ++     + +LVA  ++          K + S    PW
Sbjct: 904 EKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPW 947


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 40/207 (19%), Positives = 85/207 (41%), Gaps = 23/207 (11%)

Query: 55  AGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAE 114
           +  SEDS+  E    G PA + A P+    + P   + A + +  +  E+ ++  D E +
Sbjct: 84  SSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPG--KAAAKASESSSSEESSDDDDEEDQ 141

Query: 115 DAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTE--PRQQP---SALFARGNRKAVKS 169
             +       P       P ++ ++ ++D   +S +  P+ Q    + +  +   KA   
Sbjct: 142 KKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPK 201

Query: 170 PQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKR 229
           P R++ KI   K                +  + +  +S+   +  E    A  ++ V K+
Sbjct: 202 PARAAPKIANGK---------------AASSSSSSSSSSSSDDSEEEKAAATPKKTVPKK 246

Query: 230 KLVAQRQ-RAHSVDVEKNRKMKASSSE 255
           ++VA+   +A +    K+   + SSS+
Sbjct: 247 QVVAKAPVKAATTPTRKSSSSEDSSSD 273



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 54/218 (24%), Positives = 82/218 (37%), Gaps = 25/218 (11%)

Query: 55  AGSSEDSASSESS-------GAGGPAPRCAPPSPPPPVEP-ATQEEAERRARGAPEEQDA 106
           + SSEDS+S E            GP     PPS PPP +   TQ   +   +  P E   
Sbjct: 264 SSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSE 323

Query: 107 EAGDAEAEDAEDAALPALPVKDVEDK------PEQQTRTRETDKSPT-STEPRQQPSALF 159
           ++ D     +E+   P  P K V  K      P ++     +D S + S+E  + PS   
Sbjct: 324 DSSDESDSSSEEEKKP--PTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPS--- 378

Query: 160 ARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCA-SAPVHEIHESAL 218
               + A  +   S+      K P        KQ   G QK     A S+   E   S+ 
Sbjct: 379 ----KPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSE 434

Query: 219 RAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASSSEN 256
             K ++ V   K  A  + A S+  ++  +    SS +
Sbjct: 435 EEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSD 472



 Score = 34.3 bits (77), Expect = 0.12
 Identities = 44/214 (20%), Positives = 83/214 (38%), Gaps = 18/214 (8%)

Query: 54  PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113
           P  SSEDS+    S +        PP+     +  T+    ++A     E  +++ D+++
Sbjct: 318 PVESSEDSSDESDSSS---EEEKKPPTKAVVSKATTKPPPAKKAA----ESSSDSSDSDS 370

Query: 114 -EDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQR 172
            ED E  + PA   K+  +KP   T++     +    +P      L  R    +    + 
Sbjct: 371 SEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEES 430

Query: 173 SSSKIKENKHPF----------ALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKN 222
           SSS+ ++ K             A      KQ   GS+ + +   S+   E  E   ++  
Sbjct: 431 SSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAV 490

Query: 223 RRQVEKRKLVAQRQRAHSVDVEKNRKMKASSSEN 256
           +++ +K    A   +  S    K     +SSS++
Sbjct: 491 KKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDD 524



 Score = 31.2 bits (69), Expect = 1.00
 Identities = 31/138 (22%), Positives = 53/138 (38%), Gaps = 24/138 (17%)

Query: 54  PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113
           P   ++ S S   S +    P+   P   P    A  +   + AR AP+  + +A  + +
Sbjct: 160 PPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSS 219

Query: 114 --------EDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRK 165
                   +D+E+    A P K V   P++Q   +   K+ T+               RK
Sbjct: 220 SSSSSSSSDDSEEEKAAATPKKTV---PKKQVVAKAPVKAATTP-------------TRK 263

Query: 166 AVKSPQRSSSKIKENKHP 183
           +  S   SS + +E K P
Sbjct: 264 SSSSEDSSSDEEEEQKKP 281



 Score = 31.2 bits (69), Expect = 1.00
 Identities = 49/232 (21%), Positives = 87/232 (37%), Gaps = 54/232 (23%)

Query: 54  PAGSSEDSASSESSG--------------------AGGPAPRC--------APPSPPPPV 85
           P GS + S+ S+SS                     AGG AP          A  S     
Sbjct: 463 PQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSS 522

Query: 86  EPATQEEAER-RARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDK 144
           + +++EE E+ + +G+P  Q  +A    A  A++        K+ E++ E++ +      
Sbjct: 523 DDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGK----AAKNSEEEEEEKKKAAVVVS 578

Query: 145 SPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNV 204
              S + R+Q  A       K  ++PQ    K+ +  + F     GEK+           
Sbjct: 579 KSGSLKKRKQNEA------AKEAETPQAKKIKL-QTPNTFPKRKKGEKR----------- 620

Query: 205 CASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASSSEN 256
            AS+P   + E  +   +R  V      A+R  A       N+ +K +  ++
Sbjct: 621 -ASSPFRRVREEEIEVDSR--VADNSFDAKRGAAGDWGERANQVLKFTKGKS 669



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 18/92 (19%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 87  PATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPA----LPVKDVEDKPEQQTRTRET 142
           P  ++  ++ +    E+   E  + +   A+ AA+PA    LP      K  + + + E+
Sbjct: 73  PVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEES 132

Query: 143 DKSPTSTEPRQQPSALFARGNRKAVKSPQRSS 174
                  + ++QP     +   KA K+P + +
Sbjct: 133 SDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKA 164


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 33/132 (25%), Positives = 47/132 (35%), Gaps = 25/132 (18%)

Query: 55   AGSSEDSASSESSGAGGPAPRCAPPSP---PPPVEPATQEEAERRARGAPEEQDAEAGDA 111
            + SS  S+SS SS +   +P  A P P   P P  P      ERR+R             
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRS------------ 2677

Query: 112  EAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQ 171
                      P  P+  + D         E  +      PR Q S+   RG+R+  +   
Sbjct: 2678 ----------PRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDS 2727

Query: 172  RSSSKIKENKHP 183
            RS S  +  + P
Sbjct: 2728 RSPSHKRRRETP 2739



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 39/200 (19%), Positives = 69/200 (34%), Gaps = 22/200 (11%)

Query: 54   PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113
            P      S S  SS   GP+P  +  +   P  P     A R +R +PE +         
Sbjct: 1629 PRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR 1688

Query: 114  EDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRS 173
              +  +  P L  K    +  +   +    +S T    R+ PS        K+  S +R 
Sbjct: 1689 RSSRSS--PELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRR 1746

Query: 174  SSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKRKLVA 233
            S+                 +T T S++  +               R+++R + EK +   
Sbjct: 1747 SA--------------SSPRTKTTSRRGRSPSPKP------RGLQRSRSRSRREKTRTTR 1786

Query: 234  QRQRAHSVDVEKNRKMKASS 253
            +R R+ S      R+ ++ S
Sbjct: 1787 RRDRSGSSQSTSRRRQRSRS 1806



 Score = 31.2 bits (69), Expect = 1.00
 Identities = 45/228 (19%), Positives = 82/228 (35%), Gaps = 12/228 (5%)

Query: 53   GPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEA---ERRARGAPE------E 103
            G   S E S+S+ESS    P  R A        EP T+       R +R +PE       
Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703

Query: 104  QDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGN 163
                   + + +      P          PE   ++R + +  +++ PR + ++   R  
Sbjct: 1704 SRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSP 1763

Query: 164  RKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHE--SALRAK 221
                +  QRS S+ +  K            + + S++     + + V       S   ++
Sbjct: 1764 SPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSR 1823

Query: 222  NRRQVEKRKLVAQRQRAHSVDVEKNRKMKAS-SSENPWMTEYMRCYSA 268
            +  + E  +  ++R+R  S     +RK   S +S  PW     R   A
Sbjct: 1824 SPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPA 1871



 Score = 30.0 bits (66), Expect = 2.2
 Identities = 47/216 (21%), Positives = 80/216 (37%), Gaps = 37/216 (17%)

Query: 57   SSEDSASSESSGAGGPAPRCAPPS---PPPPVEPATQEEA-------------ERRARGA 100
            +SE + S  S     P+    PP+   P  PV  A  +++             +  + GA
Sbjct: 2420 TSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGA 2479

Query: 101  PEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFA 160
                 + AGD     +  A  P +P  DV + P              ++   QQPSAL A
Sbjct: 2480 VATTTSSAGDHNGMLSVPA--PGVPHSDVGEPP--------------ASTGAQQPSALAA 2523

Query: 161  RGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRA 220
                K  +S   SSS    +    +        + +GS  + +  +S PV    E AL+ 
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSS---SSSSSSSGSSSSDSEGSSLPVQP--EVALKR 2578

Query: 221  KNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASSSEN 256
                    ++ V + +       ++ R+  +SSS +
Sbjct: 2579 VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS 2614



 Score = 28.1 bits (61), Expect = 8.4
 Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 7/101 (6%)

Query: 160 ARGNRKAVKSPQRSSSKIKEN---KHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHES 216
           AR  ++    P +  S ++E+   + P       +K+ D G +      +S+P  E  +S
Sbjct: 157 AREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSE----SSSPRRERKKS 212

Query: 217 ALRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASSSENP 257
           + + K+R + E +K   +     S    K++K K S S  P
Sbjct: 213 SKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTP 253


>gi|190684675 X-ray repair cross complementing protein 1 [Homo
           sapiens]
          Length = 633

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 38/139 (27%), Positives = 56/139 (40%), Gaps = 26/139 (18%)

Query: 33  YRLGRRLLEQAHAPWLWDDWGPAGSSEDSASSESSGAGGPAPR------------CAPPS 80
           +R+ RRL  Q +        GP  SSE+  +S S G+G  AP+                 
Sbjct: 390 HRMRRRLPSQRYLMA-----GPGSSSEEDEASHSGGSGDEAPKLPQKQPQTKTKPTQAAG 444

Query: 81  PPPPVEPATQEEAERRARGAPEEQDAEAGDAEAED--AEDAALPALPVKDVEDKPEQQTR 138
           P  P +P T EE +  +    E+ D E   +E +D  AED+        D ED+  +   
Sbjct: 445 PSSPQKPPTPEETKAASPVLQEDIDIEGVQSEGQDNGAEDSG-------DTEDELRRVAE 497

Query: 139 TRETDKSPTSTEPRQQPSA 157
            +E    P   E  + P A
Sbjct: 498 QKEHRLPPGQEENGEDPYA 516


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 42/126 (33%), Positives = 54/126 (42%), Gaps = 22/126 (17%)

Query: 54  PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113
           PA  S   ASS  S A  P P   P +P PP  PA  E    +A+  P  Q A  G    
Sbjct: 317 PAALSRAWASSWESEAA-PEPAAPPAAPSPPDSPA--EGRLVKAQYIPGAQAATRG---- 369

Query: 114 EDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRS 173
                     LP +    KP   TR R  ++SP    PR++P A   RG R A  S +R 
Sbjct: 370 ----------LPGRAARRKPPPLTRGRSVEQSP----PRERPRAAGRRG-RMAEASGRRG 414

Query: 174 SSKIKE 179
           S + ++
Sbjct: 415 SPRARK 420


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 43/208 (20%), Positives = 83/208 (39%), Gaps = 14/208 (6%)

Query: 53  GPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAE 112
           G +GSS++  ++  +   G             VE   +E+ E    G  EE++ E  + E
Sbjct: 186 GSSGSSDEQGNNTENEEEGVEEDVEEDEE---VEEDAEEDEEVDEDGEEEEEEEEEEEEE 242

Query: 113 AEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQR 172
            E+ E+        +  +D+ +Q+    + D    +++   + S  F  G+ ++      
Sbjct: 243 EEEEEE--------EYEQDERDQKEEGNDYDTRSEASDSGSE-SVSFTDGSVRSGSGTDG 293

Query: 173 SSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKRKLV 232
           S  K KE K    +      ++  GS  + +   S   HE   S++RA  + Q  K K V
Sbjct: 294 SDEKKKERKRARGISPIVFDRS--GSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYV 351

Query: 233 AQRQRAHSVDVEKNRKMKASSSENPWMT 260
            Q  R   +    +  +  + ++  W T
Sbjct: 352 LQDARFFLIKSNNHENVSLAKAKGVWST 379


>gi|21389423 junctional sarcoplasmic reticulum protein 1 [Homo
           sapiens]
          Length = 331

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 39/140 (27%), Positives = 60/140 (42%), Gaps = 15/140 (10%)

Query: 42  QAHAPWLWDDWGPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAP 101
           QA  P   + W P  S+    SS        AP  APP+P    E   +    R A    
Sbjct: 155 QARVP---EPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAEND 211

Query: 102 EEQDAEA-GDAEAEDAEDAALPALPVKDVEDKPEQQTRTRE----TDKSPTSTEPRQQPS 156
           EE+  EA G+A  ED        L  +  +++P ++ + R+     ++ P    PR++  
Sbjct: 212 EEEPGEATGEAVREDR-----VTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEER 266

Query: 157 ALFARGNRKAVKSPQRSSSK 176
              AR  R+A+  PQR  S+
Sbjct: 267 PRAAREPREAL--PQRWESR 284


>gi|150378549 tangerin [Homo sapiens]
          Length = 1523

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 25/101 (24%), Positives = 37/101 (36%)

Query: 51  DWGPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGD 110
           D G      +S   E+ G G P  R   P P P  E  T  E E   +G P++  A   +
Sbjct: 181 DVGNLDDFAESDEDEAHGPGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPSN 240

Query: 111 AEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEP 151
           AE       + PA P +    +  ++         P +  P
Sbjct: 241 AEDTSPAPVSAPAPPARTSRGQGSERANEAGGQVGPEAPRP 281


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 32/125 (25%), Positives = 52/125 (41%), Gaps = 5/125 (4%)

Query: 54  PAGSSEDSASSESSGAGGPAPRC--APPSPPPPVEPATQEEAERRARGAPEEQDAEAGDA 111
           P  + E   ++    AGG AP+   A  +P     PA  EE  +   G P++ +A A  A
Sbjct: 100 PPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKE-EGEPKKTEAPAAPA 158

Query: 112 EAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQ 171
             E   D A  +       +       T    ++P+ST   Q P+A  +    K V++P 
Sbjct: 159 AQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKAQGPAA--SAEEPKPVEAPA 216

Query: 172 RSSSK 176
            +S +
Sbjct: 217 ANSDQ 221



 Score = 31.6 bits (70), Expect = 0.76
 Identities = 36/152 (23%), Positives = 59/152 (38%), Gaps = 23/152 (15%)

Query: 57  SSEDSASSESSGAGGPAPRCAPPSPP--------PPVEPATQEEAERRARGAPEEQDAEA 108
           + E     +++ A   AP+  P            PP  P  ++ A   A G    + AEA
Sbjct: 66  AEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEA 125

Query: 109 GDAEAEDAEDAALPALPVKDVEDK--------PEQQTRT---RETDKSPTSTE----PRQ 153
             A AE A  AA      ++ E K          Q+T++     +D  P S+E     ++
Sbjct: 126 AAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKE 185

Query: 154 QPSALFARGNRKAVKSPQRSSSKIKENKHPFA 185
            P+A  A  +    + P  S+ + K  + P A
Sbjct: 186 TPAATEAPSSTPKAQGPAASAEEPKPVEAPAA 217



 Score = 28.5 bits (62), Expect = 6.5
 Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 6/119 (5%)

Query: 58  SEDSASSESSGAGGPAPRCAPPSPPPPVEP-ATQEEAERRARGAPEEQDAEAGDAEAEDA 116
           +++ A  +   A G A        P   EP A  E AE +      +QDAE    E E  
Sbjct: 15  NDEKAKEKDKKAEGAATE--EEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGE 72

Query: 117 EDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSS 175
           +DAA  A   +  + +PE+     E    P    P Q+ +A       +A K+ + +++
Sbjct: 73  KDAA--AAKEEAPKAEPEKTEGAAEAKAEPPKA-PEQEQAAPGPAAGGEAPKAAEAAAA 128


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 5/95 (5%)

Query: 54  PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDA-- 111
           PA +   +AS  ++  G PA   AP +   PVE     E E    G+P   + EA  A  
Sbjct: 72  PAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAAS 131

Query: 112 --EAEDAEDAALPALPVKDVEDKPEQQTRTRETDK 144
              +  AED A P+ P  +   K +++   +++ K
Sbjct: 132 STSSPKAEDGATPS-PSNETPKKKKKRFSFKKSFK 165


>gi|157649073 adenylyl cyclase-associated protein [Homo sapiens]
          Length = 475

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 33/138 (23%), Positives = 52/138 (37%), Gaps = 6/138 (4%)

Query: 49  WDDWGPAGSSEDSA-SSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAE 107
           W   GP         S  S+G+G P P   PP PP      + E A R A  A   Q   
Sbjct: 207 WSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGES 266

Query: 108 AGDAEAEDAEDAALPALPVKDVEDKPEQQ-TRTRETDKSPTSTEP----RQQPSALFARG 162
              A    ++D      P    +  P +   +     K  TS  P    +++P+ L   G
Sbjct: 267 ITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEG 326

Query: 163 NRKAVKSPQRSSSKIKEN 180
            +  V++ +  S+ + E+
Sbjct: 327 KKWRVENQENVSNLVIED 344


>gi|5453595 adenylyl cyclase-associated protein [Homo sapiens]
          Length = 475

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 33/138 (23%), Positives = 52/138 (37%), Gaps = 6/138 (4%)

Query: 49  WDDWGPAGSSEDSA-SSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAE 107
           W   GP         S  S+G+G P P   PP PP      + E A R A  A   Q   
Sbjct: 207 WSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGES 266

Query: 108 AGDAEAEDAEDAALPALPVKDVEDKPEQQ-TRTRETDKSPTSTEP----RQQPSALFARG 162
              A    ++D      P    +  P +   +     K  TS  P    +++P+ L   G
Sbjct: 267 ITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEG 326

Query: 163 NRKAVKSPQRSSSKIKEN 180
            +  V++ +  S+ + E+
Sbjct: 327 KKWRVENQENVSNLVIED 344


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 48/224 (21%), Positives = 80/224 (35%), Gaps = 31/224 (13%)

Query: 42  QAHAPWLWDDWGPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAP 101
           +A AP + ++ G     E     E    G  + +            + +E +  +  G  
Sbjct: 514 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGG-------SEKEGSSEKEEGEQ 566

Query: 102 EEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQ-----------QTRTRETDKSPTSTE 150
           EE + EA +AE E+AE     A   K VE+K E+           +    E  KSP    
Sbjct: 567 EEGETEA-EAEGEEAE-----AKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 620

Query: 151 PRQQ-------PSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHN 203
           P ++        S +  +G     KSP     K    K P    G          +K  +
Sbjct: 621 PVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKS 680

Query: 204 VCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEKNR 247
               +PV E    A   K  ++ E+ K V +  +   V+ ++ +
Sbjct: 681 PVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEK 724



 Score = 29.6 bits (65), Expect = 2.9
 Identities = 29/119 (24%), Positives = 46/119 (38%), Gaps = 34/119 (28%)

Query: 79  PSPPPPVEPAT----------QEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKD 128
           P P  PVE A           +EE E+  + AP+E+  E  + + +D  +      PVK+
Sbjct: 681 PVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKE 740

Query: 129 ----------------------VEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRK 165
                                  E KP QQ + +E       +E  ++ S   A+G+RK
Sbjct: 741 EAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSE--EEGSDKGAKGSRK 797


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 48/224 (21%), Positives = 80/224 (35%), Gaps = 31/224 (13%)

Query: 42  QAHAPWLWDDWGPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAP 101
           +A AP + ++ G     E     E    G  + +            + +E +  +  G  
Sbjct: 138 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGG-------SEKEGSSEKEEGEQ 190

Query: 102 EEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQ-----------QTRTRETDKSPTSTE 150
           EE + EA +AE E+AE     A   K VE+K E+           +    E  KSP    
Sbjct: 191 EEGETEA-EAEGEEAE-----AKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 244

Query: 151 PRQQ-------PSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHN 203
           P ++        S +  +G     KSP     K    K P    G          +K  +
Sbjct: 245 PVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKS 304

Query: 204 VCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEKNR 247
               +PV E    A   K  ++ E+ K V +  +   V+ ++ +
Sbjct: 305 PVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEK 348



 Score = 29.6 bits (65), Expect = 2.9
 Identities = 29/119 (24%), Positives = 46/119 (38%), Gaps = 34/119 (28%)

Query: 79  PSPPPPVEPAT----------QEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKD 128
           P P  PVE A           +EE E+  + AP+E+  E  + + +D  +      PVK+
Sbjct: 305 PVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKE 364

Query: 129 ----------------------VEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRK 165
                                  E KP QQ + +E       +E  ++ S   A+G+RK
Sbjct: 365 EAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSE--EEGSDKGAKGSRK 421


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 22/166 (13%)

Query: 82  PPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRE 141
           PPPVEP  +E+ E       ++ +A A D E E  E   +  + VK+  ++ E++    E
Sbjct: 487 PPPVEPEEEEDTE---DAGLDDWEAMASDEETEKVEGNKV-HIEVKENPEEEEEEEEEEE 542

Query: 142 TDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKT 201
            D+     E  +  S            S ++ S K  + K    +    E  +D    K 
Sbjct: 543 EDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTK- 601

Query: 202 HNVCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEKNR 247
                        E     K +R++EKR+L    + + +V+ EK R
Sbjct: 602 -------------EERAYDKAKRRIEKRRL----EHSKNVNTEKLR 630



 Score = 29.6 bits (65), Expect = 2.9
 Identities = 26/132 (19%), Positives = 46/132 (34%), Gaps = 7/132 (5%)

Query: 50  DDWGPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAG 109
           DDW    S E++   E    G         +P    E   +EE +  +    EE+    G
Sbjct: 504 DDWEAMASDEETEKVE----GNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEG 559

Query: 110 DAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKS 169
               E+ E  +      K ++ KP ++     +D    S + R +    + +  R+  K 
Sbjct: 560 SEGDEEDEKVSDEKDSGKTLDKKPSKE---MSSDSEYDSDDDRTKEERAYDKAKRRIEKR 616

Query: 170 PQRSSSKIKENK 181
               S  +   K
Sbjct: 617 RLEHSKNVNTEK 628


>gi|147902746 MEX3A protein [Homo sapiens]
          Length = 520

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 30/81 (37%), Positives = 35/81 (43%), Gaps = 5/81 (6%)

Query: 68  GAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVK 127
           G G PA   APP P PP  PA    A   A  A   Q   A     + A DA L AL  K
Sbjct: 66  GGGAPAQPAAPPQPAPPPPPAAPPAAPTAAPAAQTPQPPTA----PKGASDAKLCAL-YK 120

Query: 128 DVEDKPEQQTRTRETDKSPTS 148
           + E + +  + T E    PTS
Sbjct: 121 EAELRLKGSSNTTECVPVPTS 141


>gi|199559779 coiled-coil domain containing 8 [Homo sapiens]
          Length = 538

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 23/192 (11%)

Query: 50  DDWGPAGSS--EDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRAR-GAPEEQDA 106
           D  G A  S  E++ + +  GA G     AP           +EEA    R GAP E+ A
Sbjct: 294 DQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGA 353

Query: 107 EAGDAEAEDAEDAALPALPVKDVEDKPEQQT--RTRETDKSPTSTEPRQQPSALFARGNR 164
           EA D + E+A D      P     D+  Q T     E   +  +  P  Q S +      
Sbjct: 354 EAADNQREEAADNQRAEAPA----DQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQRE 409

Query: 165 KAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAP-VHEIHESALR---- 219
           +AV   +  +  ++   +  A    G++     ++  HN  A AP + E   SA +    
Sbjct: 410 EAVHDQRERAPAVQGADNQRAQARAGQR-----AEAAHNQRAGAPGIQEAEVSAAQGTTG 464

Query: 220 ----AKNRRQVE 227
               A+ R+QV+
Sbjct: 465 TAPGARARKQVK 476


>gi|130502140 NEZHA isoform 2 [Homo sapiens]
          Length = 1249

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 56/216 (25%), Positives = 88/216 (40%), Gaps = 31/216 (14%)

Query: 61  SASSESSGAGGPAPRCAPPSPPP-PVEPATQEEAERRARGA-PEEQDAEAGDA------- 111
           S SS+S G   PAP   P  PPP P +  T EEA +    A P      A D        
Sbjct: 429 SVSSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSP 488

Query: 112 EAEDAEDAALPALP---VKDVEDKPEQQTRTRETDKSPTSTEP-----RQQPSALFARGN 163
           E       A P LP    K + D+P +        ++P+   P       +P A  + G+
Sbjct: 489 EGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAP-SEGS 547

Query: 164 RKAV-KSPQRSSSKIK-----ENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESA 217
            KAV  SP  ++S++K     E K         E +   GS  +      A   E+ E +
Sbjct: 548 PKAVASSPAATNSEVKMTSFAERKKQLVK---AEAEAGAGSPTSTPAPPEALSSEMSELS 604

Query: 218 LRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASS 253
            R + +R    R + AQ++R  ++  +  +++  S+
Sbjct: 605 ARLEEKR----RAIEAQKRRIEAIFAKHRQRLGKSA 636


>gi|122937255 NEZHA isoform 1 [Homo sapiens]
          Length = 1276

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 56/216 (25%), Positives = 88/216 (40%), Gaps = 31/216 (14%)

Query: 61  SASSESSGAGGPAPRCAPPSPPP-PVEPATQEEAERRARGA-PEEQDAEAGDA------- 111
           S SS+S G   PAP   P  PPP P +  T EEA +    A P      A D        
Sbjct: 456 SVSSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSP 515

Query: 112 EAEDAEDAALPALP---VKDVEDKPEQQTRTRETDKSPTSTEP-----RQQPSALFARGN 163
           E       A P LP    K + D+P +        ++P+   P       +P A  + G+
Sbjct: 516 EGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAP-SEGS 574

Query: 164 RKAV-KSPQRSSSKIK-----ENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESA 217
            KAV  SP  ++S++K     E K         E +   GS  +      A   E+ E +
Sbjct: 575 PKAVASSPAATNSEVKMTSFAERKKQLVK---AEAEAGAGSPTSTPAPPEALSSEMSELS 631

Query: 218 LRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASS 253
            R + +R    R + AQ++R  ++  +  +++  S+
Sbjct: 632 ARLEEKR----RAIEAQKRRIEAIFAKHRQRLGKSA 663


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
           [Homo sapiens]
          Length = 1412

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 36/157 (22%)

Query: 54  PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113
           P G S     + + G G P  + A P PP  V PAT       A+    E+D+E+   E+
Sbjct: 422 PLGKSPQVKPASTMGMG-PLGKGAGPVPPGKVGPATPS-----AQVGKWEEDSESSSEES 475

Query: 114 EDAEDAALP----------------ALPVKDVEDKPEQQT--------------RTRETD 143
            D+ D  +P                A P       P Q+                +  ++
Sbjct: 476 SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 535

Query: 144 KSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKEN 180
           +S  S +  + P+A+ A   + A+K PQ  +   K N
Sbjct: 536 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 572



 Score = 33.1 bits (74), Expect = 0.26
 Identities = 51/207 (24%), Positives = 78/207 (37%), Gaps = 50/207 (24%)

Query: 55   AGSSEDS-ASSESSGAGGPAPRCA-------PP--------SPPPPVEPATQEEAE---R 95
            AG  +DS +SSE S + G AP          PP        SP  P     Q +A    R
Sbjct: 849  AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 908

Query: 96   RARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQP 155
            +AR +     + + ++E ED   A     P              R    +  +  PR  P
Sbjct: 909  KARASESTARSSSSESEDEDVIPATQCLTP------------GIRTNVVTMPTAHPRIAP 956

Query: 156  SALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHE 215
             A  A        S  + SS+I +          G+KQ    +Q +    AS P   + +
Sbjct: 957  KASMAGA------SSSKESSRISD----------GKKQEGPATQVSKKNPASLP---LTQ 997

Query: 216  SALRAKNRRQVEKRKLVAQRQRAHSVD 242
            +AL+   ++  E +  VA+ Q +  VD
Sbjct: 998  AALKVLAQKASEAQPPVARTQPSSGVD 1024



 Score = 32.0 bits (71), Expect = 0.58
 Identities = 22/116 (18%), Positives = 43/116 (37%)

Query: 61  SASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAA 120
           S  +   GA     + +P     P  P     A  +A+    E+D+++   E++  E+A 
Sbjct: 288 SGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 347

Query: 121 LPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSK 176
             A P              +E+ +   +  P ++     A+      +   RSSS+
Sbjct: 348 AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 403



 Score = 28.5 bits (62), Expect = 6.5
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 10/93 (10%)

Query: 61  SASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAA 120
           +AS+ + G  G     APP     V  A+Q +A     G PEE D+E+   E+ D+E+  
Sbjct: 225 AASAPAKGTPGKGATPAPPGKAGAV--ASQTKA-----GKPEE-DSESSSEESSDSEEET 276

Query: 121 LPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQ 153
             A  +  ++ K   +T       +P    PR+
Sbjct: 277 PAAKAL--LQAKASGKTSQVGAASAPAKESPRK 307


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 36/157 (22%)

Query: 54  PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113
           P G S     + + G G P  + A P PP  V PAT       A+    E+D+E+   E+
Sbjct: 499 PLGKSPQVKPASTMGMG-PLGKGAGPVPPGKVGPATPS-----AQVGKWEEDSESSSEES 552

Query: 114 EDAEDAALP----------------ALPVKDVEDKPEQQT--------------RTRETD 143
            D+ D  +P                A P       P Q+                +  ++
Sbjct: 553 SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 612

Query: 144 KSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKEN 180
           +S  S +  + P+A+ A   + A+K PQ  +   K N
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649



 Score = 32.3 bits (72), Expect = 0.45
 Identities = 45/199 (22%), Positives = 67/199 (33%), Gaps = 11/199 (5%)

Query: 53  GPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAE 112
           G A SS +  SS S            P+       +T+E   R+A  AP     + GD  
Sbjct: 194 GQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAP----GKVGDVT 249

Query: 113 AEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEP---RQQPSALFARGNRKAVKS 169
            +    A  PA   K    KPE+++ + E         P   R Q  A       +A  +
Sbjct: 250 PQVKGGALPPAKRAK----KPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA 305

Query: 170 PQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKR 229
           P + +        P    G    QT  G  +  +  +S    +  E    AK   Q +  
Sbjct: 306 PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKAS 365

Query: 230 KLVAQRQRAHSVDVEKNRK 248
              +Q   A +   E  RK
Sbjct: 366 GKTSQVGAASAPAKESPRK 384



 Score = 32.0 bits (71), Expect = 0.58
 Identities = 22/116 (18%), Positives = 43/116 (37%)

Query: 61  SASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAA 120
           S  +   GA     + +P     P  P     A  +A+    E+D+++   E++  E+A 
Sbjct: 365 SGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 424

Query: 121 LPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSK 176
             A P              +E+ +   +  P ++     A+      +   RSSS+
Sbjct: 425 AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480



 Score = 31.6 bits (70), Expect = 0.76
 Identities = 49/219 (22%), Positives = 80/219 (36%), Gaps = 48/219 (21%)

Query: 55   AGSSEDS-ASSESSGAGGPAPRCA-------PP--------SPPPPVEPATQEEAE---R 95
            AG  +DS +SSE S + G AP          PP        SP  P     Q +A    R
Sbjct: 926  AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 985

Query: 96   RARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQP 155
            +AR +     + + ++E ED   A     P              R    +  +  PR  P
Sbjct: 986  KARASESTARSSSSESEDEDVIPATQCLTP------------GIRTNVVTMPTAHPRIAP 1033

Query: 156  SALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHE 215
             A  A        S  + SS+I +          G+KQ    +Q   +   + P      
Sbjct: 1034 KASMAGA------SSSKESSRISD----------GKKQEGPATQ-VDSAVGTLPATSPQS 1076

Query: 216  SALRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASSS 254
            ++++AK   ++ K KL   +Q   + +   + +  + SS
Sbjct: 1077 TSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSS 1115


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.124    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,695,264
Number of Sequences: 37866
Number of extensions: 711468
Number of successful extensions: 13318
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 347
Number of HSP's successfully gapped in prelim test: 848
Number of HSP's that attempted gapping in prelim test: 8926
Number of HSP's gapped (non-prelim): 4169
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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