BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|188219563 hypothetical protein LOC126731 [Homo sapiens] (270 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|188219563 hypothetical protein LOC126731 [Homo sapiens] 559 e-160 gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 46 3e-05 gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 46 3e-05 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 45 7e-05 gi|23503317 coiled-coil domain containing 96 [Homo sapiens] 45 9e-05 gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 44 1e-04 gi|83921602 solute carrier family 38, member 10 isoform a [Homo ... 44 1e-04 gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 43 3e-04 gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 43 3e-04 gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 43 3e-04 gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 43 3e-04 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 43 3e-04 gi|190684675 X-ray repair cross complementing protein 1 [Homo sa... 42 4e-04 gi|182507165 thymus expressed gene 3-like [Homo sapiens] 42 4e-04 gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 42 6e-04 gi|21389423 junctional sarcoplasmic reticulum protein 1 [Homo sa... 42 7e-04 gi|150378549 tangerin [Homo sapiens] 41 0.001 gi|30795231 brain abundant, membrane attached signal protein 1 [... 40 0.002 gi|153070260 myristoylated alanine-rich protein kinase C substra... 40 0.002 gi|157649073 adenylyl cyclase-associated protein [Homo sapiens] 40 0.002 gi|5453595 adenylyl cyclase-associated protein [Homo sapiens] 40 0.002 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 40 0.002 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 40 0.002 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 40 0.003 gi|147902746 MEX3A protein [Homo sapiens] 40 0.003 gi|199559779 coiled-coil domain containing 8 [Homo sapiens] 39 0.004 gi|130502140 NEZHA isoform 2 [Homo sapiens] 39 0.005 gi|122937255 NEZHA isoform 1 [Homo sapiens] 39 0.005 gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 39 0.005 gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 39 0.005 >gi|188219563 hypothetical protein LOC126731 [Homo sapiens] Length = 270 Score = 559 bits (1441), Expect = e-160 Identities = 270/270 (100%), Positives = 270/270 (100%) Query: 1 MSPGSGVKSEYMKRYQEPRWEEYGPCYRELLHYRLGRRLLEQAHAPWLWDDWGPAGSSED 60 MSPGSGVKSEYMKRYQEPRWEEYGPCYRELLHYRLGRRLLEQAHAPWLWDDWGPAGSSED Sbjct: 1 MSPGSGVKSEYMKRYQEPRWEEYGPCYRELLHYRLGRRLLEQAHAPWLWDDWGPAGSSED 60 Query: 61 SASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAA 120 SASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAA Sbjct: 61 SASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAA 120 Query: 121 LPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKEN 180 LPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKEN Sbjct: 121 LPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKEN 180 Query: 181 KHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHS 240 KHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHS Sbjct: 181 KHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHS 240 Query: 241 VDVEKNRKMKASSSENPWMTEYMRCYSARA 270 VDVEKNRKMKASSSENPWMTEYMRCYSARA Sbjct: 241 VDVEKNRKMKASSSENPWMTEYMRCYSARA 270 >gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens] Length = 2462 Score = 46.2 bits (108), Expect = 3e-05 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 2/95 (2%) Query: 58 SEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAE 117 +E + +SE++GA P P PS PPPV P ++E E A EE + + A E A Sbjct: 777 TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAV 836 Query: 118 DAALPALPVKD--VEDKPEQQTRTRETDKSPTSTE 150 D PVK E+ E + ++ + + + E Sbjct: 837 DTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAE 871 Score = 34.7 bits (78), Expect = 0.090 Identities = 42/189 (22%), Positives = 77/189 (40%), Gaps = 28/189 (14%) Query: 58 SEDSASSESSGAGGPAPRC---------APPSPPPPVEPA-TQEEAERRARGAPEEQDAE 107 S + +++ +G GP P PP+PPP PA T+ A GAP A Sbjct: 736 SPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAP 795 Query: 108 AGDA--------EAEDAEDAALPALPVKDVEDKPEQQTRTRETDKS--PTSTEPRQQPSA 157 + E ++ E AA P + + + P + +T K+ P +E ++ Sbjct: 796 PSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEE 855 Query: 158 LFARG-NRKAVKSPQRSSSKIKENKHPFALYGWGEKQT--DTGSQKTHNVCASAPVHEIH 214 A+G + +A ++ + K ++ + G G T +G+ + + A+ E+ Sbjct: 856 GPAKGKDAEAAEATAEGALKAEKKEG-----GSGRATTAKSSGAPQDSDSSATCSADEVD 910 Query: 215 ESALRAKNR 223 E+ KNR Sbjct: 911 EAEGGDKNR 919 Score = 29.3 bits (64), Expect = 3.8 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 7/56 (12%) Query: 44 HAPWLWDDWGPAGSSEDSASSESSGAGGPAPRCAPPS---PPPPVEPATQEEAERR 96 HAP W P +S S G GG + R A S P+ P TQ+ ++R Sbjct: 1814 HAPI----WRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQR 1865 Score = 28.9 bits (63), Expect = 4.9 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 11/88 (12%) Query: 90 QEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTST 149 Q++ + R + EE+D + + EAE E+ +VE+ E + + D TS Sbjct: 506 QQQQQPMPRSSQEEKDEKEKEKEAEKEEEK-------PEVENDKEDLLKEKTDD---TSG 555 Query: 150 EPRQQPSALFARGNRKAVKSPQRSSSKI 177 E + A+ ++G RK S R +I Sbjct: 556 EDNDEKEAVASKG-RKTANSQGRRKGRI 582 Score = 28.5 bits (62), Expect = 6.5 Identities = 12/49 (24%), Positives = 24/49 (48%) Query: 59 EDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAE 107 ED+A ++ + P P+ P P +P + + R+ P +++AE Sbjct: 970 EDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAE 1018 >gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens] Length = 2524 Score = 46.2 bits (108), Expect = 3e-05 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 2/95 (2%) Query: 58 SEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAE 117 +E + +SE++GA P P PS PPPV P ++E E A EE + + A E A Sbjct: 794 TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAV 853 Query: 118 DAALPALPVKD--VEDKPEQQTRTRETDKSPTSTE 150 D PVK E+ E + ++ + + + E Sbjct: 854 DTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAE 888 Score = 34.7 bits (78), Expect = 0.090 Identities = 42/189 (22%), Positives = 77/189 (40%), Gaps = 28/189 (14%) Query: 58 SEDSASSESSGAGGPAPRC---------APPSPPPPVEPA-TQEEAERRARGAPEEQDAE 107 S + +++ +G GP P PP+PPP PA T+ A GAP A Sbjct: 753 SPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAP 812 Query: 108 AGDA--------EAEDAEDAALPALPVKDVEDKPEQQTRTRETDKS--PTSTEPRQQPSA 157 + E ++ E AA P + + + P + +T K+ P +E ++ Sbjct: 813 PSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEE 872 Query: 158 LFARG-NRKAVKSPQRSSSKIKENKHPFALYGWGEKQT--DTGSQKTHNVCASAPVHEIH 214 A+G + +A ++ + K ++ + G G T +G+ + + A+ E+ Sbjct: 873 GPAKGKDAEAAEATAEGALKAEKKEG-----GSGRATTAKSSGAPQDSDSSATCSADEVD 927 Query: 215 ESALRAKNR 223 E+ KNR Sbjct: 928 EAEGGDKNR 936 Score = 29.3 bits (64), Expect = 3.8 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 7/56 (12%) Query: 44 HAPWLWDDWGPAGSSEDSASSESSGAGGPAPRCAPPS---PPPPVEPATQEEAERR 96 HAP W P +S S G GG + R A S P+ P TQ+ ++R Sbjct: 1830 HAPI----WRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQR 1881 Score = 28.9 bits (63), Expect = 4.9 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 11/88 (12%) Query: 90 QEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTST 149 Q++ + R + EE+D + + EAE E+ +VE+ E + + D TS Sbjct: 506 QQQQQPMPRSSQEEKDEKEKEKEAEKEEEK-------PEVENDKEDLLKEKTDD---TSG 555 Query: 150 EPRQQPSALFARGNRKAVKSPQRSSSKI 177 E + A+ ++G RK S R +I Sbjct: 556 EDNDEKEAVASKG-RKTANSQGRRKGRI 582 Score = 28.5 bits (62), Expect = 6.5 Identities = 12/49 (24%), Positives = 24/49 (48%) Query: 59 EDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAE 107 ED+A ++ + P P+ P P +P + + R+ P +++AE Sbjct: 986 EDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAE 1034 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 45.1 bits (105), Expect = 7e-05 Identities = 49/202 (24%), Positives = 84/202 (41%), Gaps = 19/202 (9%) Query: 56 GSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAED 115 G E++ S + A P P +EEA+ A E++ AE + Sbjct: 496 GGEEETKSPPAEEAASPEKEAKSP---------VKEEAKSPAEAKSPEKEEAKSPAEVKS 546 Query: 116 AEDAALPALPVKDVEDKPEQQTRTRETDKSPT---STEPRQQPSALFARGNRKAVKSPQR 172 E A PA ++ + PE ++ +E KSP S E + P+ A+ +A KSP++ Sbjct: 547 PEKAKSPA--KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA-KSPEK 603 Query: 173 SSSKIKEN-KHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKRKL 231 + S +KE K P +++ + ++ A +P E +S +AK+ EK + Sbjct: 604 AKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS---PEKEEA 660 Query: 232 VAQRQRAHSVDVEKNRKMKASS 253 + + V E KA S Sbjct: 661 KSPEKAKSPVKAEAKSPEKAKS 682 Score = 39.7 bits (91), Expect = 0.003 Identities = 53/222 (23%), Positives = 95/222 (42%), Gaps = 29/222 (13%) Query: 55 AGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAE----RRARGAPEEQDAEAGD 110 A S ++ S E A PA +P P + + AE +A+ +E+ + Sbjct: 558 AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617 Query: 111 AEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSP---TSTEPRQQPSALFARGNRKA- 166 A++ E+A PA +V+ + ++ T+E KSP S E + S A+ KA Sbjct: 618 AKSPVKEEAKSPA----EVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAE 673 Query: 167 VKSPQRSSSKIK-ENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKN--- 222 KSP+++ S +K E K P + ++ + A +PV E +S +AK+ Sbjct: 674 AKSPEKAKSPVKAEAKSP------EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727 Query: 223 --RRQVEKRKLVAQR-----QRAHSVDVEKNRKMKASSSENP 257 + EK K + ++A S + K +K+ ++ P Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP 769 Score = 37.7 bits (86), Expect = 0.011 Identities = 47/187 (25%), Positives = 82/187 (43%), Gaps = 19/187 (10%) Query: 86 EPATQEEAERRARGAPEEQDAEAGDAEAED-------AEDAALP----ALPVKDVEDKP- 133 E +EE E + EE+ E +AE + AE+AA P PVK+ P Sbjct: 469 EVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPA 528 Query: 134 EQQTRTRETDKSPT---STEPRQQPSALFARGNRKAVKSPQRSSSKI-KENKHPFALYGW 189 E ++ +E KSP S E + P+ A+ +A KSP++ +K E K P Sbjct: 529 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA-KSPEKEEAKSPAEVKSPEKAKSP 587 Query: 190 GEKQTDTGSQKTHNVCASAPVHEIHESALRAKN--RRQVEKRKLVAQRQRAHSVDVEKNR 247 +++ + ++ A +PV E +S AK+ + + + V ++A S E+ + Sbjct: 588 AKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAK 647 Query: 248 KMKASSS 254 + + S Sbjct: 648 SPEKAKS 654 Score = 35.8 bits (81), Expect = 0.040 Identities = 40/169 (23%), Positives = 71/169 (42%), Gaps = 11/169 (6%) Query: 89 TQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPA-LPVKDVEDKPEQQTRT--RETDKS 145 T+E E + A EE+ E E E+AE P + PE++ ++ +E KS Sbjct: 467 TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS 526 Query: 146 PTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKEN-KHPFALYGWGEKQTDTGSQKTHNV 204 P + ++ A + VKSP+++ S KE K P +++ + ++ Sbjct: 527 PAEAKSPEKEEA----KSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPE 582 Query: 205 CASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASS 253 A +P E +S AK+ EK K + + + + K +A S Sbjct: 583 KAKSPAKEEAKSPAEAKS---PEKAKSPVKEEAKSPAEAKSPVKEEAKS 628 Score = 35.4 bits (80), Expect = 0.053 Identities = 39/175 (22%), Positives = 62/175 (35%), Gaps = 23/175 (13%) Query: 87 PATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSP 146 P + A+ AR ++ +A E+ + P+K+ PE++ +E KSP Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823 Query: 147 TSTEPRQQPSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCA 206 E + Q VK P + K +E K P T +K + Sbjct: 824 VKEEEKPQ---------EVKVKEPPK---KAEEEKAP---------ATPKTEEKKDSKKE 862 Query: 207 SAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASSSENPWMTE 261 AP E + + K VEK K + A + E +K+ E P E Sbjct: 863 EAPKKEAPKPKVEEKKEPAVEKPK--ESKVEAKKEEAEDKKKVPTPEKEAPAKVE 915 Score = 34.3 bits (77), Expect = 0.12 Identities = 36/139 (25%), Positives = 58/139 (41%), Gaps = 18/139 (12%) Query: 55 AGSSEDSASSESSGAGGPAPRCAPP---SP-------PPPVEPATQEEAERRARGAPEEQ 104 A S ++ S E A PA +P SP PP + +EEA+ A E+ Sbjct: 524 AKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEK 583 Query: 105 DAEAGDAEAEDAEDAALPAL---PVKDVEDKP-EQQTRTRETDKSPTSTEPRQQPSALFA 160 EA+ +A P PVK+ P E ++ +E KSP + ++ + Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS--- 640 Query: 161 RGNRKAVKSPQRSSSKIKE 179 ++ KSP+++ S KE Sbjct: 641 -PTKEEAKSPEKAKSPEKE 658 Score = 33.5 bits (75), Expect = 0.20 Identities = 35/165 (21%), Positives = 67/165 (40%), Gaps = 14/165 (8%) Query: 82 PPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRE 141 P + +E+A+ + P++++ ++ E E ++ + P K E+K +T E Sbjct: 796 PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEE 855 Query: 142 TDKSPTSTEPRQQ-PSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQK 200 S P+++ P AV+ P+ S + K+ E+ D Sbjct: 856 KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKK-----------EEAEDKKKVP 904 Query: 201 THNVCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEK 245 T A A V E+ E A + K + +V K++ + + S EK Sbjct: 905 TPEKEAPAKV-EVKEDA-KPKEKTEVAKKEPDDAKAKEPSKPAEK 947 Score = 32.7 bits (73), Expect = 0.34 Identities = 29/112 (25%), Positives = 47/112 (41%), Gaps = 7/112 (6%) Query: 72 PAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVED 131 P P P+ E A +E A+ P++ A+ AE E A ++ Sbjct: 904 PTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAK 963 Query: 132 KPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKENKHP 183 KPE++ +T K T + +PS KA K+ + SS+ K++K P Sbjct: 964 KPEEKPKTEAKAKEDDKTLSK-EPS------KPKAEKAEKSSSTDQKDSKPP 1008 >gi|23503317 coiled-coil domain containing 96 [Homo sapiens] Length = 555 Score = 44.7 bits (104), Expect = 9e-05 Identities = 43/180 (23%), Positives = 66/180 (36%), Gaps = 14/180 (7%) Query: 54 PAGSSEDSASSESSGAGGPAPRCAP-PSPPPPVEPATQEEAERRARGAPEEQDAEAGDAE 112 P G + A+ E G G P P P P P E +E A+ PEE +AEAG E Sbjct: 70 PKGLTAAEAAGEE-GPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEE 128 Query: 113 AEDAED-------AALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRK 165 E A + A+LP + + E + T + E Q+ A + + Sbjct: 129 LEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAETERVEGEEEDKEETQRDGAESKERDGE 188 Query: 166 AVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQ 225 + + K + F W E+ QK + + + + S L +NR Q Sbjct: 189 GRPAKSQEEGKRLYGRDEFEDLEWSEE-----VQKLQEQQLRSDLLDQYRSLLVERNRSQ 243 Score = 39.3 bits (90), Expect = 0.004 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 4/122 (3%) Query: 50 DDWGPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARG---APEEQDA 106 D G G E A+ S P +P EP +EE + ++G A E+ +A Sbjct: 10 DPGGEGGDGESLAARPSKIKASSGPPTSPEPGELESEPEEEEEEQAASQGGTAADEQAEA 69 Query: 107 EAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKA 166 G AE A + P P + E +PE + + P EP P L A + Sbjct: 70 PKGLTAAEAAGEEG-PGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEE 128 Query: 167 VK 168 ++ Sbjct: 129 LE 130 >gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens] Length = 1341 Score = 44.3 bits (103), Expect = 1e-04 Identities = 49/187 (26%), Positives = 79/187 (42%), Gaps = 34/187 (18%) Query: 74 PRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKP 133 PR P PPPPV+P AE+R EQ+ + AE ++ E + Sbjct: 1114 PRPLHPPPPPPVQPPQHPRAEQR------EQERAVREQWAE------------REREMER 1155 Query: 134 EQQTRT-RETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEK 192 ++TR+ RE D+ PR + + R +A ++S K K + P A K Sbjct: 1156 RERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPA------K 1209 Query: 193 QTDTGSQKTH--------NVCASAPVHEIHESALRAKNRRQVEK-RKLVAQRQRAHSVDV 243 D +KT + S V + E A RAK R + K ++ Q++R + Sbjct: 1210 LLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAER 1269 Query: 244 EKNRKMK 250 E+NR+++ Sbjct: 1270 ERNRQLE 1276 Score = 29.3 bits (64), Expect = 3.8 Identities = 19/75 (25%), Positives = 30/75 (40%), Gaps = 10/75 (13%) Query: 81 PPPPVEPATQE-------EAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDV---E 130 PP +P T E E+ER E+++ +E D P +P+ D + Sbjct: 740 PPAATQPQTSETQTSHLPESERIHHTVEEKEEVTMDTSENRPENDVPEPPMPIADQVSND 799 Query: 131 DKPEQQTRTRETDKS 145 D+PE E +S Sbjct: 800 DRPEGSVEDEEKKES 814 >gi|83921602 solute carrier family 38, member 10 isoform a [Homo sapiens] Length = 1119 Score = 43.9 bits (102), Expect = 1e-04 Identities = 40/150 (26%), Positives = 52/150 (34%), Gaps = 22/150 (14%) Query: 55 AGSSEDSASSESSGAGGPAPRCAP-PSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113 AG + A G P P P P P P EP Q + ER Q EAG AE Sbjct: 636 AGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEM 695 Query: 114 EDAE-----------------DAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPS 156 D D L V + + K Q R + + P E Q+P Sbjct: 696 LDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQEDEEDKPRQVEVHQEPG 755 Query: 157 ALFARGNRKAVKSPQRSSSKIKENKHPFAL 186 A RG ++P+ + + EN P L Sbjct: 756 AAVPRGQ----EAPEGKARETVENLPPLPL 781 Score = 28.5 bits (62), Expect = 6.5 Identities = 31/115 (26%), Positives = 41/115 (35%), Gaps = 18/115 (15%) Query: 66 SSGAGGPAP----RCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAAL 121 S AGG AP + APP P E E+ E R + EAGD ED + Sbjct: 524 SRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDL-PEDPQ---- 578 Query: 122 PALPVKDVEDKPEQQTRTRETDKSPTSTEPR------QQPSALFARGNRKAVKSP 170 V + + +P Q + PR +Q + L G KA P Sbjct: 579 ---KVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGP 630 >gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 43.1 bits (100), Expect = 3e-04 Identities = 39/137 (28%), Positives = 59/137 (43%), Gaps = 19/137 (13%) Query: 56 GSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAER----RARGAPEEQDAEAGDA 111 G ED+ASSE A PA P EP +EE E+ + EE+ E + Sbjct: 1239 GEEEDAASSEVPAAS-PADSSNSPETETK-EPEVEEEEEKPRVSEEQRQSEEEQQELEEP 1296 Query: 112 EAEDAEDAALPALP-----VKDVEDKPEQQTRTRETDKSPTSTEPRQQPSA--LFARGNR 164 E E+ EDAA D +D + T+ +E ++ PT + +++P F N Sbjct: 1297 EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANM 1356 Query: 165 KAVKSPQRSSSKIKENK 181 Q+S KIK+ + Sbjct: 1357 ------QKSREKIKDKE 1367 Score = 35.0 bits (79), Expect = 0.069 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 10/79 (12%) Query: 79 PSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTR 138 P P+ +EE E +A E ++AE G E EDA + +PA D + PE +T+ Sbjct: 1213 PKEDMPLPEERKEEEEMQA----EAEEAEEG--EEEDAASSEVPAASPADSSNSPETETK 1266 Query: 139 ----TRETDKSPTSTEPRQ 153 E +K S E RQ Sbjct: 1267 EPEVEEEEEKPRVSEEQRQ 1285 Score = 28.5 bits (62), Expect = 6.5 Identities = 33/164 (20%), Positives = 63/164 (38%), Gaps = 13/164 (7%) Query: 102 EEQDAEAGDAEAEDAEDAALPALPVKDV-EDKPEQQTRTRETDKSPTSTEP---RQQPSA 157 EE++AE G+ E ++ L K V + EQ + + E++K P P + Sbjct: 790 EEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQ 849 Query: 158 LFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESA 217 + + A P R ++N+ +G D S+ +SAP + E Sbjct: 850 VLPHDSLPANSQPSRRGRWGRKNRKTQERFG------DKDSKLLLEETSSAPQEQYGECG 903 Query: 218 LRAKNRRQ---VEKRKLVAQRQRAHSVDVEKNRKMKASSSENPW 258 +++ ++ + +LVA ++ K + S PW Sbjct: 904 EKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPW 947 >gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 43.1 bits (100), Expect = 3e-04 Identities = 39/137 (28%), Positives = 59/137 (43%), Gaps = 19/137 (13%) Query: 56 GSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAER----RARGAPEEQDAEAGDA 111 G ED+ASSE A PA P EP +EE E+ + EE+ E + Sbjct: 1239 GEEEDAASSEVPAAS-PADSSNSPETETK-EPEVEEEEEKPRVSEEQRQSEEEQQELEEP 1296 Query: 112 EAEDAEDAALPALP-----VKDVEDKPEQQTRTRETDKSPTSTEPRQQPSA--LFARGNR 164 E E+ EDAA D +D + T+ +E ++ PT + +++P F N Sbjct: 1297 EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANM 1356 Query: 165 KAVKSPQRSSSKIKENK 181 Q+S KIK+ + Sbjct: 1357 ------QKSREKIKDKE 1367 Score = 35.0 bits (79), Expect = 0.069 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 10/79 (12%) Query: 79 PSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTR 138 P P+ +EE E +A E ++AE G E EDA + +PA D + PE +T+ Sbjct: 1213 PKEDMPLPEERKEEEEMQA----EAEEAEEG--EEEDAASSEVPAASPADSSNSPETETK 1266 Query: 139 ----TRETDKSPTSTEPRQ 153 E +K S E RQ Sbjct: 1267 EPEVEEEEEKPRVSEEQRQ 1285 Score = 28.5 bits (62), Expect = 6.5 Identities = 33/164 (20%), Positives = 63/164 (38%), Gaps = 13/164 (7%) Query: 102 EEQDAEAGDAEAEDAEDAALPALPVKDV-EDKPEQQTRTRETDKSPTSTEP---RQQPSA 157 EE++AE G+ E ++ L K V + EQ + + E++K P P + Sbjct: 790 EEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQ 849 Query: 158 LFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESA 217 + + A P R ++N+ +G D S+ +SAP + E Sbjct: 850 VLPHDSLPANSQPSRRGRWGRKNRKTQERFG------DKDSKLLLEETSSAPQEQYGECG 903 Query: 218 LRAKNRRQ---VEKRKLVAQRQRAHSVDVEKNRKMKASSSENPW 258 +++ ++ + +LVA ++ K + S PW Sbjct: 904 EKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPW 947 >gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 43.1 bits (100), Expect = 3e-04 Identities = 39/137 (28%), Positives = 59/137 (43%), Gaps = 19/137 (13%) Query: 56 GSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAER----RARGAPEEQDAEAGDA 111 G ED+ASSE A PA P EP +EE E+ + EE+ E + Sbjct: 1239 GEEEDAASSEVPAAS-PADSSNSPETETK-EPEVEEEEEKPRVSEEQRQSEEEQQELEEP 1296 Query: 112 EAEDAEDAALPALP-----VKDVEDKPEQQTRTRETDKSPTSTEPRQQPSA--LFARGNR 164 E E+ EDAA D +D + T+ +E ++ PT + +++P F N Sbjct: 1297 EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANM 1356 Query: 165 KAVKSPQRSSSKIKENK 181 Q+S KIK+ + Sbjct: 1357 ------QKSREKIKDKE 1367 Score = 35.0 bits (79), Expect = 0.069 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 10/79 (12%) Query: 79 PSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTR 138 P P+ +EE E +A E ++AE G E EDA + +PA D + PE +T+ Sbjct: 1213 PKEDMPLPEERKEEEEMQA----EAEEAEEG--EEEDAASSEVPAASPADSSNSPETETK 1266 Query: 139 ----TRETDKSPTSTEPRQ 153 E +K S E RQ Sbjct: 1267 EPEVEEEEEKPRVSEEQRQ 1285 Score = 28.5 bits (62), Expect = 6.5 Identities = 33/164 (20%), Positives = 63/164 (38%), Gaps = 13/164 (7%) Query: 102 EEQDAEAGDAEAEDAEDAALPALPVKDV-EDKPEQQTRTRETDKSPTSTEP---RQQPSA 157 EE++AE G+ E ++ L K V + EQ + + E++K P P + Sbjct: 790 EEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQ 849 Query: 158 LFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESA 217 + + A P R ++N+ +G D S+ +SAP + E Sbjct: 850 VLPHDSLPANSQPSRRGRWGRKNRKTQERFG------DKDSKLLLEETSSAPQEQYGECG 903 Query: 218 LRAKNRRQ---VEKRKLVAQRQRAHSVDVEKNRKMKASSSENPW 258 +++ ++ + +LVA ++ K + S PW Sbjct: 904 EKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPW 947 >gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sapiens] Length = 699 Score = 42.7 bits (99), Expect = 3e-04 Identities = 40/207 (19%), Positives = 85/207 (41%), Gaps = 23/207 (11%) Query: 55 AGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAE 114 + SEDS+ E G PA + A P+ + P + A + + + E+ ++ D E + Sbjct: 84 SSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPG--KAAAKASESSSSEESSDDDDEEDQ 141 Query: 115 DAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTE--PRQQP---SALFARGNRKAVKS 169 + P P ++ ++ ++D +S + P+ Q + + + KA Sbjct: 142 KKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPK 201 Query: 170 PQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKR 229 P R++ KI K + + + +S+ + E A ++ V K+ Sbjct: 202 PARAAPKIANGK---------------AASSSSSSSSSSSSDDSEEEKAAATPKKTVPKK 246 Query: 230 KLVAQRQ-RAHSVDVEKNRKMKASSSE 255 ++VA+ +A + K+ + SSS+ Sbjct: 247 QVVAKAPVKAATTPTRKSSSSEDSSSD 273 Score = 39.7 bits (91), Expect = 0.003 Identities = 54/218 (24%), Positives = 82/218 (37%), Gaps = 25/218 (11%) Query: 55 AGSSEDSASSESS-------GAGGPAPRCAPPSPPPPVEP-ATQEEAERRARGAPEEQDA 106 + SSEDS+S E GP PPS PPP + TQ + + P E Sbjct: 264 SSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSE 323 Query: 107 EAGDAEAEDAEDAALPALPVKDVEDK------PEQQTRTRETDKSPT-STEPRQQPSALF 159 ++ D +E+ P P K V K P ++ +D S + S+E + PS Sbjct: 324 DSSDESDSSSEEEKKP--PTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPS--- 378 Query: 160 ARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCA-SAPVHEIHESAL 218 + A + S+ K P KQ G QK A S+ E S+ Sbjct: 379 ----KPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSE 434 Query: 219 RAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASSSEN 256 K ++ V K A + A S+ ++ + SS + Sbjct: 435 EEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSD 472 Score = 34.3 bits (77), Expect = 0.12 Identities = 44/214 (20%), Positives = 83/214 (38%), Gaps = 18/214 (8%) Query: 54 PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113 P SSEDS+ S + PP+ + T+ ++A E +++ D+++ Sbjct: 318 PVESSEDSSDESDSSS---EEEKKPPTKAVVSKATTKPPPAKKAA----ESSSDSSDSDS 370 Query: 114 -EDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQR 172 ED E + PA K+ +KP T++ + +P L R + + Sbjct: 371 SEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEES 430 Query: 173 SSSKIKENKHPF----------ALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKN 222 SSS+ ++ K A KQ GS+ + + S+ E E ++ Sbjct: 431 SSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAV 490 Query: 223 RRQVEKRKLVAQRQRAHSVDVEKNRKMKASSSEN 256 +++ +K A + S K +SSS++ Sbjct: 491 KKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDD 524 Score = 31.2 bits (69), Expect = 1.00 Identities = 31/138 (22%), Positives = 53/138 (38%), Gaps = 24/138 (17%) Query: 54 PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113 P ++ S S S + P+ P P A + + AR AP+ + +A + + Sbjct: 160 PPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSS 219 Query: 114 --------EDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRK 165 +D+E+ A P K V P++Q + K+ T+ RK Sbjct: 220 SSSSSSSSDDSEEEKAAATPKKTV---PKKQVVAKAPVKAATTP-------------TRK 263 Query: 166 AVKSPQRSSSKIKENKHP 183 + S SS + +E K P Sbjct: 264 SSSSEDSSSDEEEEQKKP 281 Score = 31.2 bits (69), Expect = 1.00 Identities = 49/232 (21%), Positives = 87/232 (37%), Gaps = 54/232 (23%) Query: 54 PAGSSEDSASSESSG--------------------AGGPAPRC--------APPSPPPPV 85 P GS + S+ S+SS AGG AP A S Sbjct: 463 PQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSS 522 Query: 86 EPATQEEAER-RARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDK 144 + +++EE E+ + +G+P Q +A A A++ K+ E++ E++ + Sbjct: 523 DDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGK----AAKNSEEEEEEKKKAAVVVS 578 Query: 145 SPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNV 204 S + R+Q A K ++PQ K+ + + F GEK+ Sbjct: 579 KSGSLKKRKQNEA------AKEAETPQAKKIKL-QTPNTFPKRKKGEKR----------- 620 Query: 205 CASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASSSEN 256 AS+P + E + +R V A+R A N+ +K + ++ Sbjct: 621 -ASSPFRRVREEEIEVDSR--VADNSFDAKRGAAGDWGERANQVLKFTKGKS 669 Score = 30.8 bits (68), Expect = 1.3 Identities = 18/92 (19%), Positives = 39/92 (42%), Gaps = 4/92 (4%) Query: 87 PATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPA----LPVKDVEDKPEQQTRTRET 142 P ++ ++ + E+ E + + A+ AA+PA LP K + + + E+ Sbjct: 73 PVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEES 132 Query: 143 DKSPTSTEPRQQPSALFARGNRKAVKSPQRSS 174 + ++QP + KA K+P + + Sbjct: 133 SDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKA 164 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 42.7 bits (99), Expect = 3e-04 Identities = 33/132 (25%), Positives = 47/132 (35%), Gaps = 25/132 (18%) Query: 55 AGSSEDSASSESSGAGGPAPRCAPPSP---PPPVEPATQEEAERRARGAPEEQDAEAGDA 111 + SS S+SS SS + +P A P P P P P ERR+R Sbjct: 2630 SSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRS------------ 2677 Query: 112 EAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQ 171 P P+ + D E + PR Q S+ RG+R+ + Sbjct: 2678 ----------PRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDS 2727 Query: 172 RSSSKIKENKHP 183 RS S + + P Sbjct: 2728 RSPSHKRRRETP 2739 Score = 33.9 bits (76), Expect = 0.15 Identities = 39/200 (19%), Positives = 69/200 (34%), Gaps = 22/200 (11%) Query: 54 PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113 P S S SS GP+P + + P P A R +R +PE + Sbjct: 1629 PRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR 1688 Query: 114 EDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRS 173 + + P L K + + + +S T R+ PS K+ S +R Sbjct: 1689 RSSRSS--PELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRR 1746 Query: 174 SSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKRKLVA 233 S+ +T T S++ + R+++R + EK + Sbjct: 1747 SA--------------SSPRTKTTSRRGRSPSPKP------RGLQRSRSRSRREKTRTTR 1786 Query: 234 QRQRAHSVDVEKNRKMKASS 253 +R R+ S R+ ++ S Sbjct: 1787 RRDRSGSSQSTSRRRQRSRS 1806 Score = 31.2 bits (69), Expect = 1.00 Identities = 45/228 (19%), Positives = 82/228 (35%), Gaps = 12/228 (5%) Query: 53 GPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEA---ERRARGAPE------E 103 G S E S+S+ESS P R A EP T+ R +R +PE Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703 Query: 104 QDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGN 163 + + + P PE ++R + + +++ PR + ++ R Sbjct: 1704 SRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSP 1763 Query: 164 RKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHE--SALRAK 221 + QRS S+ + K + + S++ + + V S ++ Sbjct: 1764 SPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSR 1823 Query: 222 NRRQVEKRKLVAQRQRAHSVDVEKNRKMKAS-SSENPWMTEYMRCYSA 268 + + E + ++R+R S +RK S +S PW R A Sbjct: 1824 SPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPA 1871 Score = 30.0 bits (66), Expect = 2.2 Identities = 47/216 (21%), Positives = 80/216 (37%), Gaps = 37/216 (17%) Query: 57 SSEDSASSESSGAGGPAPRCAPPS---PPPPVEPATQEEA-------------ERRARGA 100 +SE + S S P+ PP+ P PV A +++ + + GA Sbjct: 2420 TSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGA 2479 Query: 101 PEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFA 160 + AGD + A P +P DV + P ++ QQPSAL A Sbjct: 2480 VATTTSSAGDHNGMLSVPA--PGVPHSDVGEPP--------------ASTGAQQPSALAA 2523 Query: 161 RGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRA 220 K +S SSS + + + +GS + + +S PV E AL+ Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSS---SSSSSSSGSSSSDSEGSSLPVQP--EVALKR 2578 Query: 221 KNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASSSEN 256 ++ V + + ++ R+ +SSS + Sbjct: 2579 VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS 2614 Score = 28.1 bits (61), Expect = 8.4 Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 7/101 (6%) Query: 160 ARGNRKAVKSPQRSSSKIKEN---KHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHES 216 AR ++ P + S ++E+ + P +K+ D G + +S+P E +S Sbjct: 157 AREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSE----SSSPRRERKKS 212 Query: 217 ALRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASSSENP 257 + + K+R + E +K + S K++K K S S P Sbjct: 213 SKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTP 253 >gi|190684675 X-ray repair cross complementing protein 1 [Homo sapiens] Length = 633 Score = 42.4 bits (98), Expect = 4e-04 Identities = 38/139 (27%), Positives = 56/139 (40%), Gaps = 26/139 (18%) Query: 33 YRLGRRLLEQAHAPWLWDDWGPAGSSEDSASSESSGAGGPAPR------------CAPPS 80 +R+ RRL Q + GP SSE+ +S S G+G AP+ Sbjct: 390 HRMRRRLPSQRYLMA-----GPGSSSEEDEASHSGGSGDEAPKLPQKQPQTKTKPTQAAG 444 Query: 81 PPPPVEPATQEEAERRARGAPEEQDAEAGDAEAED--AEDAALPALPVKDVEDKPEQQTR 138 P P +P T EE + + E+ D E +E +D AED+ D ED+ + Sbjct: 445 PSSPQKPPTPEETKAASPVLQEDIDIEGVQSEGQDNGAEDSG-------DTEDELRRVAE 497 Query: 139 TRETDKSPTSTEPRQQPSA 157 +E P E + P A Sbjct: 498 QKEHRLPPGQEENGEDPYA 516 >gi|182507165 thymus expressed gene 3-like [Homo sapiens] Length = 629 Score = 42.4 bits (98), Expect = 4e-04 Identities = 42/126 (33%), Positives = 54/126 (42%), Gaps = 22/126 (17%) Query: 54 PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113 PA S ASS S A P P P +P PP PA E +A+ P Q A G Sbjct: 317 PAALSRAWASSWESEAA-PEPAAPPAAPSPPDSPA--EGRLVKAQYIPGAQAATRG---- 369 Query: 114 EDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRS 173 LP + KP TR R ++SP PR++P A RG R A S +R Sbjct: 370 ----------LPGRAARRKPPPLTRGRSVEQSP----PRERPRAAGRRG-RMAEASGRRG 414 Query: 174 SSKIKE 179 S + ++ Sbjct: 415 SPRARK 420 >gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] Length = 727 Score = 42.0 bits (97), Expect = 6e-04 Identities = 43/208 (20%), Positives = 83/208 (39%), Gaps = 14/208 (6%) Query: 53 GPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAE 112 G +GSS++ ++ + G VE +E+ E G EE++ E + E Sbjct: 186 GSSGSSDEQGNNTENEEEGVEEDVEEDEE---VEEDAEEDEEVDEDGEEEEEEEEEEEEE 242 Query: 113 AEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQR 172 E+ E+ + +D+ +Q+ + D +++ + S F G+ ++ Sbjct: 243 EEEEEE--------EYEQDERDQKEEGNDYDTRSEASDSGSE-SVSFTDGSVRSGSGTDG 293 Query: 173 SSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKRKLV 232 S K KE K + ++ GS + + S HE S++RA + Q K K V Sbjct: 294 SDEKKKERKRARGISPIVFDRS--GSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYV 351 Query: 233 AQRQRAHSVDVEKNRKMKASSSENPWMT 260 Q R + + + + ++ W T Sbjct: 352 LQDARFFLIKSNNHENVSLAKAKGVWST 379 >gi|21389423 junctional sarcoplasmic reticulum protein 1 [Homo sapiens] Length = 331 Score = 41.6 bits (96), Expect = 7e-04 Identities = 39/140 (27%), Positives = 60/140 (42%), Gaps = 15/140 (10%) Query: 42 QAHAPWLWDDWGPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAP 101 QA P + W P S+ SS AP APP+P E + R A Sbjct: 155 QARVP---EPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAEND 211 Query: 102 EEQDAEA-GDAEAEDAEDAALPALPVKDVEDKPEQQTRTRE----TDKSPTSTEPRQQPS 156 EE+ EA G+A ED L + +++P ++ + R+ ++ P PR++ Sbjct: 212 EEEPGEATGEAVREDR-----VTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEER 266 Query: 157 ALFARGNRKAVKSPQRSSSK 176 AR R+A+ PQR S+ Sbjct: 267 PRAAREPREAL--PQRWESR 284 >gi|150378549 tangerin [Homo sapiens] Length = 1523 Score = 40.8 bits (94), Expect = 0.001 Identities = 25/101 (24%), Positives = 37/101 (36%) Query: 51 DWGPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGD 110 D G +S E+ G G P R P P P E T E E +G P++ A + Sbjct: 181 DVGNLDDFAESDEDEAHGPGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPSN 240 Query: 111 AEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEP 151 AE + PA P + + ++ P + P Sbjct: 241 AEDTSPAPVSAPAPPARTSRGQGSERANEAGGQVGPEAPRP 281 >gi|30795231 brain abundant, membrane attached signal protein 1 [Homo sapiens] Length = 227 Score = 40.4 bits (93), Expect = 0.002 Identities = 32/125 (25%), Positives = 52/125 (41%), Gaps = 5/125 (4%) Query: 54 PAGSSEDSASSESSGAGGPAPRC--APPSPPPPVEPATQEEAERRARGAPEEQDAEAGDA 111 P + E ++ AGG AP+ A +P PA EE + G P++ +A A A Sbjct: 100 PPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKE-EGEPKKTEAPAAPA 158 Query: 112 EAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQ 171 E D A + + T ++P+ST Q P+A + K V++P Sbjct: 159 AQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKAQGPAA--SAEEPKPVEAPA 216 Query: 172 RSSSK 176 +S + Sbjct: 217 ANSDQ 221 Score = 31.6 bits (70), Expect = 0.76 Identities = 36/152 (23%), Positives = 59/152 (38%), Gaps = 23/152 (15%) Query: 57 SSEDSASSESSGAGGPAPRCAPPSPP--------PPVEPATQEEAERRARGAPEEQDAEA 108 + E +++ A AP+ P PP P ++ A A G + AEA Sbjct: 66 AEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEA 125 Query: 109 GDAEAEDAEDAALPALPVKDVEDK--------PEQQTRT---RETDKSPTSTE----PRQ 153 A AE A AA ++ E K Q+T++ +D P S+E ++ Sbjct: 126 AAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKE 185 Query: 154 QPSALFARGNRKAVKSPQRSSSKIKENKHPFA 185 P+A A + + P S+ + K + P A Sbjct: 186 TPAATEAPSSTPKAQGPAASAEEPKPVEAPAA 217 Score = 28.5 bits (62), Expect = 6.5 Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 6/119 (5%) Query: 58 SEDSASSESSGAGGPAPRCAPPSPPPPVEP-ATQEEAERRARGAPEEQDAEAGDAEAEDA 116 +++ A + A G A P EP A E AE + +QDAE E E Sbjct: 15 NDEKAKEKDKKAEGAATE--EEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGE 72 Query: 117 EDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSS 175 +DAA A + + +PE+ E P P Q+ +A +A K+ + +++ Sbjct: 73 KDAA--AAKEEAPKAEPEKTEGAAEAKAEPPKA-PEQEQAAPGPAAGGEAPKAAEAAAA 128 >gi|153070260 myristoylated alanine-rich protein kinase C substrate [Homo sapiens] Length = 332 Score = 40.0 bits (92), Expect = 0.002 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 5/95 (5%) Query: 54 PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDA-- 111 PA + +AS ++ G PA AP + PVE E E G+P + EA A Sbjct: 72 PAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAAS 131 Query: 112 --EAEDAEDAALPALPVKDVEDKPEQQTRTRETDK 144 + AED A P+ P + K +++ +++ K Sbjct: 132 STSSPKAEDGATPS-PSNETPKKKKKRFSFKKSFK 165 >gi|157649073 adenylyl cyclase-associated protein [Homo sapiens] Length = 475 Score = 40.0 bits (92), Expect = 0.002 Identities = 33/138 (23%), Positives = 52/138 (37%), Gaps = 6/138 (4%) Query: 49 WDDWGPAGSSEDSA-SSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAE 107 W GP S S+G+G P P PP PP + E A R A A Q Sbjct: 207 WSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGES 266 Query: 108 AGDAEAEDAEDAALPALPVKDVEDKPEQQ-TRTRETDKSPTSTEP----RQQPSALFARG 162 A ++D P + P + + K TS P +++P+ L G Sbjct: 267 ITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEG 326 Query: 163 NRKAVKSPQRSSSKIKEN 180 + V++ + S+ + E+ Sbjct: 327 KKWRVENQENVSNLVIED 344 >gi|5453595 adenylyl cyclase-associated protein [Homo sapiens] Length = 475 Score = 40.0 bits (92), Expect = 0.002 Identities = 33/138 (23%), Positives = 52/138 (37%), Gaps = 6/138 (4%) Query: 49 WDDWGPAGSSEDSA-SSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAE 107 W GP S S+G+G P P PP PP + E A R A A Q Sbjct: 207 WSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGES 266 Query: 108 AGDAEAEDAEDAALPALPVKDVEDKPEQQ-TRTRETDKSPTSTEP----RQQPSALFARG 162 A ++D P + P + + K TS P +++P+ L G Sbjct: 267 ITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEG 326 Query: 163 NRKAVKSPQRSSSKIKEN 180 + V++ + S+ + E+ Sbjct: 327 KKWRVENQENVSNLVIED 344 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 40.0 bits (92), Expect = 0.002 Identities = 48/224 (21%), Positives = 80/224 (35%), Gaps = 31/224 (13%) Query: 42 QAHAPWLWDDWGPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAP 101 +A AP + ++ G E E G + + + +E + + G Sbjct: 514 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGG-------SEKEGSSEKEEGEQ 566 Query: 102 EEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQ-----------QTRTRETDKSPTSTE 150 EE + EA +AE E+AE A K VE+K E+ + E KSP Sbjct: 567 EEGETEA-EAEGEEAE-----AKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 620 Query: 151 PRQQ-------PSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHN 203 P ++ S + +G KSP K K P G +K + Sbjct: 621 PVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKS 680 Query: 204 VCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEKNR 247 +PV E A K ++ E+ K V + + V+ ++ + Sbjct: 681 PVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEK 724 Score = 29.6 bits (65), Expect = 2.9 Identities = 29/119 (24%), Positives = 46/119 (38%), Gaps = 34/119 (28%) Query: 79 PSPPPPVEPAT----------QEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKD 128 P P PVE A +EE E+ + AP+E+ E + + +D + PVK+ Sbjct: 681 PVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKE 740 Query: 129 ----------------------VEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRK 165 E KP QQ + +E +E ++ S A+G+RK Sbjct: 741 EAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSE--EEGSDKGAKGSRK 797 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 40.0 bits (92), Expect = 0.002 Identities = 48/224 (21%), Positives = 80/224 (35%), Gaps = 31/224 (13%) Query: 42 QAHAPWLWDDWGPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAP 101 +A AP + ++ G E E G + + + +E + + G Sbjct: 138 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGG-------SEKEGSSEKEEGEQ 190 Query: 102 EEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQ-----------QTRTRETDKSPTSTE 150 EE + EA +AE E+AE A K VE+K E+ + E KSP Sbjct: 191 EEGETEA-EAEGEEAE-----AKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 244 Query: 151 PRQQ-------PSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHN 203 P ++ S + +G KSP K K P G +K + Sbjct: 245 PVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKS 304 Query: 204 VCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEKNR 247 +PV E A K ++ E+ K V + + V+ ++ + Sbjct: 305 PVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEK 348 Score = 29.6 bits (65), Expect = 2.9 Identities = 29/119 (24%), Positives = 46/119 (38%), Gaps = 34/119 (28%) Query: 79 PSPPPPVEPAT----------QEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKD 128 P P PVE A +EE E+ + AP+E+ E + + +D + PVK+ Sbjct: 305 PVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKE 364 Query: 129 ----------------------VEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRK 165 E KP QQ + +E +E ++ S A+G+RK Sbjct: 365 EAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSE--EEGSDKGAKGSRK 421 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 39.7 bits (91), Expect = 0.003 Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 22/166 (13%) Query: 82 PPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRE 141 PPPVEP +E+ E ++ +A A D E E E + + VK+ ++ E++ E Sbjct: 487 PPPVEPEEEEDTE---DAGLDDWEAMASDEETEKVEGNKV-HIEVKENPEEEEEEEEEEE 542 Query: 142 TDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKT 201 D+ E + S S ++ S K + K + E +D K Sbjct: 543 EDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTK- 601 Query: 202 HNVCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEKNR 247 E K +R++EKR+L + + +V+ EK R Sbjct: 602 -------------EERAYDKAKRRIEKRRL----EHSKNVNTEKLR 630 Score = 29.6 bits (65), Expect = 2.9 Identities = 26/132 (19%), Positives = 46/132 (34%), Gaps = 7/132 (5%) Query: 50 DDWGPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAG 109 DDW S E++ E G +P E +EE + + EE+ G Sbjct: 504 DDWEAMASDEETEKVE----GNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEG 559 Query: 110 DAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKS 169 E+ E + K ++ KP ++ +D S + R + + + R+ K Sbjct: 560 SEGDEEDEKVSDEKDSGKTLDKKPSKE---MSSDSEYDSDDDRTKEERAYDKAKRRIEKR 616 Query: 170 PQRSSSKIKENK 181 S + K Sbjct: 617 RLEHSKNVNTEK 628 >gi|147902746 MEX3A protein [Homo sapiens] Length = 520 Score = 39.7 bits (91), Expect = 0.003 Identities = 30/81 (37%), Positives = 35/81 (43%), Gaps = 5/81 (6%) Query: 68 GAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVK 127 G G PA APP P PP PA A A A Q A + A DA L AL K Sbjct: 66 GGGAPAQPAAPPQPAPPPPPAAPPAAPTAAPAAQTPQPPTA----PKGASDAKLCAL-YK 120 Query: 128 DVEDKPEQQTRTRETDKSPTS 148 + E + + + T E PTS Sbjct: 121 EAELRLKGSSNTTECVPVPTS 141 >gi|199559779 coiled-coil domain containing 8 [Homo sapiens] Length = 538 Score = 39.3 bits (90), Expect = 0.004 Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 23/192 (11%) Query: 50 DDWGPAGSS--EDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRAR-GAPEEQDA 106 D G A S E++ + + GA G AP +EEA R GAP E+ A Sbjct: 294 DQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGA 353 Query: 107 EAGDAEAEDAEDAALPALPVKDVEDKPEQQT--RTRETDKSPTSTEPRQQPSALFARGNR 164 EA D + E+A D P D+ Q T E + + P Q S + Sbjct: 354 EAADNQREEAADNQRAEAPA----DQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQRE 409 Query: 165 KAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAP-VHEIHESALR---- 219 +AV + + ++ + A G++ ++ HN A AP + E SA + Sbjct: 410 EAVHDQRERAPAVQGADNQRAQARAGQR-----AEAAHNQRAGAPGIQEAEVSAAQGTTG 464 Query: 220 ----AKNRRQVE 227 A+ R+QV+ Sbjct: 465 TAPGARARKQVK 476 >gi|130502140 NEZHA isoform 2 [Homo sapiens] Length = 1249 Score = 38.9 bits (89), Expect = 0.005 Identities = 56/216 (25%), Positives = 88/216 (40%), Gaps = 31/216 (14%) Query: 61 SASSESSGAGGPAPRCAPPSPPP-PVEPATQEEAERRARGA-PEEQDAEAGDA------- 111 S SS+S G PAP P PPP P + T EEA + A P A D Sbjct: 429 SVSSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSP 488 Query: 112 EAEDAEDAALPALP---VKDVEDKPEQQTRTRETDKSPTSTEP-----RQQPSALFARGN 163 E A P LP K + D+P + ++P+ P +P A + G+ Sbjct: 489 EGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAP-SEGS 547 Query: 164 RKAV-KSPQRSSSKIK-----ENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESA 217 KAV SP ++S++K E K E + GS + A E+ E + Sbjct: 548 PKAVASSPAATNSEVKMTSFAERKKQLVK---AEAEAGAGSPTSTPAPPEALSSEMSELS 604 Query: 218 LRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASS 253 R + +R R + AQ++R ++ + +++ S+ Sbjct: 605 ARLEEKR----RAIEAQKRRIEAIFAKHRQRLGKSA 636 >gi|122937255 NEZHA isoform 1 [Homo sapiens] Length = 1276 Score = 38.9 bits (89), Expect = 0.005 Identities = 56/216 (25%), Positives = 88/216 (40%), Gaps = 31/216 (14%) Query: 61 SASSESSGAGGPAPRCAPPSPPP-PVEPATQEEAERRARGA-PEEQDAEAGDA------- 111 S SS+S G PAP P PPP P + T EEA + A P A D Sbjct: 456 SVSSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSP 515 Query: 112 EAEDAEDAALPALP---VKDVEDKPEQQTRTRETDKSPTSTEP-----RQQPSALFARGN 163 E A P LP K + D+P + ++P+ P +P A + G+ Sbjct: 516 EGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAP-SEGS 574 Query: 164 RKAV-KSPQRSSSKIK-----ENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESA 217 KAV SP ++S++K E K E + GS + A E+ E + Sbjct: 575 PKAVASSPAATNSEVKMTSFAERKKQLVK---AEAEAGAGSPTSTPAPPEALSSEMSELS 631 Query: 218 LRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASS 253 R + +R R + AQ++R ++ + +++ S+ Sbjct: 632 ARLEEKR----RAIEAQKRRIEAIFAKHRQRLGKSA 663 >gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f [Homo sapiens] Length = 1412 Score = 38.9 bits (89), Expect = 0.005 Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 36/157 (22%) Query: 54 PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113 P G S + + G G P + A P PP V PAT A+ E+D+E+ E+ Sbjct: 422 PLGKSPQVKPASTMGMG-PLGKGAGPVPPGKVGPATPS-----AQVGKWEEDSESSSEES 475 Query: 114 EDAEDAALP----------------ALPVKDVEDKPEQQT--------------RTRETD 143 D+ D +P A P P Q+ + ++ Sbjct: 476 SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 535 Query: 144 KSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKEN 180 +S S + + P+A+ A + A+K PQ + K N Sbjct: 536 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 572 Score = 33.1 bits (74), Expect = 0.26 Identities = 51/207 (24%), Positives = 78/207 (37%), Gaps = 50/207 (24%) Query: 55 AGSSEDS-ASSESSGAGGPAPRCA-------PP--------SPPPPVEPATQEEAE---R 95 AG +DS +SSE S + G AP PP SP P Q +A R Sbjct: 849 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 908 Query: 96 RARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQP 155 +AR + + + ++E ED A P R + + PR P Sbjct: 909 KARASESTARSSSSESEDEDVIPATQCLTP------------GIRTNVVTMPTAHPRIAP 956 Query: 156 SALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHE 215 A A S + SS+I + G+KQ +Q + AS P + + Sbjct: 957 KASMAGA------SSSKESSRISD----------GKKQEGPATQVSKKNPASLP---LTQ 997 Query: 216 SALRAKNRRQVEKRKLVAQRQRAHSVD 242 +AL+ ++ E + VA+ Q + VD Sbjct: 998 AALKVLAQKASEAQPPVARTQPSSGVD 1024 Score = 32.0 bits (71), Expect = 0.58 Identities = 22/116 (18%), Positives = 43/116 (37%) Query: 61 SASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAA 120 S + GA + +P P P A +A+ E+D+++ E++ E+A Sbjct: 288 SGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 347 Query: 121 LPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSK 176 A P +E+ + + P ++ A+ + RSSS+ Sbjct: 348 AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 403 Score = 28.5 bits (62), Expect = 6.5 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 10/93 (10%) Query: 61 SASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAA 120 +AS+ + G G APP V A+Q +A G PEE D+E+ E+ D+E+ Sbjct: 225 AASAPAKGTPGKGATPAPPGKAGAV--ASQTKA-----GKPEE-DSESSSEESSDSEEET 276 Query: 121 LPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQ 153 A + ++ K +T +P PR+ Sbjct: 277 PAAKAL--LQAKASGKTSQVGAASAPAKESPRK 307 >gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e [Homo sapiens] Length = 1451 Score = 38.9 bits (89), Expect = 0.005 Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 36/157 (22%) Query: 54 PAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEA 113 P G S + + G G P + A P PP V PAT A+ E+D+E+ E+ Sbjct: 499 PLGKSPQVKPASTMGMG-PLGKGAGPVPPGKVGPATPS-----AQVGKWEEDSESSSEES 552 Query: 114 EDAEDAALP----------------ALPVKDVEDKPEQQT--------------RTRETD 143 D+ D +P A P P Q+ + ++ Sbjct: 553 SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 612 Query: 144 KSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKEN 180 +S S + + P+A+ A + A+K PQ + K N Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649 Score = 32.3 bits (72), Expect = 0.45 Identities = 45/199 (22%), Positives = 67/199 (33%), Gaps = 11/199 (5%) Query: 53 GPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAE 112 G A SS + SS S P+ +T+E R+A AP + GD Sbjct: 194 GQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAP----GKVGDVT 249 Query: 113 AEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEP---RQQPSALFARGNRKAVKS 169 + A PA K KPE+++ + E P R Q A +A + Sbjct: 250 PQVKGGALPPAKRAK----KPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA 305 Query: 170 PQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKR 229 P + + P G QT G + + +S + E AK Q + Sbjct: 306 PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKAS 365 Query: 230 KLVAQRQRAHSVDVEKNRK 248 +Q A + E RK Sbjct: 366 GKTSQVGAASAPAKESPRK 384 Score = 32.0 bits (71), Expect = 0.58 Identities = 22/116 (18%), Positives = 43/116 (37%) Query: 61 SASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAA 120 S + GA + +P P P A +A+ E+D+++ E++ E+A Sbjct: 365 SGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 424 Query: 121 LPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSK 176 A P +E+ + + P ++ A+ + RSSS+ Sbjct: 425 AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480 Score = 31.6 bits (70), Expect = 0.76 Identities = 49/219 (22%), Positives = 80/219 (36%), Gaps = 48/219 (21%) Query: 55 AGSSEDS-ASSESSGAGGPAPRCA-------PP--------SPPPPVEPATQEEAE---R 95 AG +DS +SSE S + G AP PP SP P Q +A R Sbjct: 926 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 985 Query: 96 RARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQP 155 +AR + + + ++E ED A P R + + PR P Sbjct: 986 KARASESTARSSSSESEDEDVIPATQCLTP------------GIRTNVVTMPTAHPRIAP 1033 Query: 156 SALFARGNRKAVKSPQRSSSKIKENKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHE 215 A A S + SS+I + G+KQ +Q + + P Sbjct: 1034 KASMAGA------SSSKESSRISD----------GKKQEGPATQ-VDSAVGTLPATSPQS 1076 Query: 216 SALRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASSS 254 ++++AK ++ K KL +Q + + + + + SS Sbjct: 1077 TSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSS 1115 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.124 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,695,264 Number of Sequences: 37866 Number of extensions: 711468 Number of successful extensions: 13318 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 347 Number of HSP's successfully gapped in prelim test: 848 Number of HSP's that attempted gapping in prelim test: 8926 Number of HSP's gapped (non-prelim): 4169 length of query: 270 length of database: 18,247,518 effective HSP length: 101 effective length of query: 169 effective length of database: 14,423,052 effective search space: 2437495788 effective search space used: 2437495788 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.