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Search of human proteins with 188219541
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188219541 DENN/MADD domain containing 1B isoform 2 [Homo
sapiens]
(426 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188219541 DENN/MADD domain containing 1B isoform 2 [Homo sapi... 868 0.0
gi|218563726 DENN/MADD domain containing 1B isoform 1 [Homo sapi... 791 0.0
gi|55749789 DENN/MADD domain containing 1A isoform 2 [Homo sapiens] 550 e-157
gi|55749779 DENN/MADD domain containing 1A isoform 1 [Homo sapiens] 550 e-157
gi|113205087 DENN/MADD domain containing 1C [Homo sapiens] 445 e-125
gi|154813195 DENN/MADD domain containing 2A [Homo sapiens] 143 3e-34
gi|21361991 DENN/MADD domain containing 2D [Homo sapiens] 135 7e-32
gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo sapi... 134 1e-31
gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo sapi... 134 1e-31
gi|21264614 suppression of tumorigenicity 5 isoform 2 [Homo sapi... 134 1e-31
gi|121949817 DENN/MADD domain containing 2C [Homo sapiens] 124 1e-28
gi|94818781 DENN/MADD domain containing 4C [Homo sapiens] 79 6e-15
gi|29788755 SET binding factor 2 [Homo sapiens] 79 8e-15
gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo sapi... 75 9e-14
gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo sapi... 75 9e-14
gi|44889475 RAB6 interacting protein 1 [Homo sapiens] 73 4e-13
gi|50345870 DENN/MADD domain containing 3 [Homo sapiens] 72 7e-13
gi|239735519 SET binding factor 1 [Homo sapiens] 71 2e-12
gi|122891862 DENN/MADD domain containing 5B [Homo sapiens] 71 2e-12
gi|148922920 DENN/MADD domain containing 4B [Homo sapiens] 69 6e-12
gi|209863002 MAP-kinase activating death domain-containing prote... 56 7e-08
gi|209862998 MAP-kinase activating death domain-containing prote... 56 7e-08
gi|209862994 MAP-kinase activating death domain-containing prote... 56 7e-08
gi|18860873 MAP-kinase activating death domain-containing protei... 56 7e-08
gi|209862987 MAP-kinase activating death domain-containing prote... 56 7e-08
gi|209862983 MAP-kinase activating death domain-containing prote... 56 7e-08
gi|209862979 MAP-kinase activating death domain-containing prote... 56 7e-08
gi|209862975 MAP-kinase activating death domain-containing prote... 56 7e-08
gi|209862971 MAP-kinase activating death domain-containing prote... 56 7e-08
gi|209571517 MAP-kinase activating death domain-containing prote... 56 7e-08
>gi|188219541 DENN/MADD domain containing 1B isoform 2 [Homo
sapiens]
Length = 426
Score = 868 bits (2243), Expect = 0.0
Identities = 426/426 (100%), Positives = 426/426 (100%)
Query: 1 MDCRTKANPDRTFDLVLKVKCHASENEDPVVLWKFPEDFGDQEILQSVPKFCFPFDVERV 60
MDCRTKANPDRTFDLVLKVKCHASENEDPVVLWKFPEDFGDQEILQSVPKFCFPFDVERV
Sbjct: 1 MDCRTKANPDRTFDLVLKVKCHASENEDPVVLWKFPEDFGDQEILQSVPKFCFPFDVERV 60
Query: 61 SQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYLAK 120
SQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYLAK
Sbjct: 61 SQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYLAK 120
Query: 121 ELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTG 180
ELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTG
Sbjct: 121 ELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTG 180
Query: 181 LPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMY 240
LPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMY
Sbjct: 181 LPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMY 240
Query: 241 WQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFSDL 300
WQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFSDL
Sbjct: 241 WQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFSDL 300
Query: 301 NNLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEESF 360
NNLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEESF
Sbjct: 301 NNLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEESF 360
Query: 361 VKHRSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGGKDKLQY 420
VKHRSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGGKDKLQY
Sbjct: 361 VKHRSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGGKDKLQY 420
Query: 421 DYPFSQ 426
DYPFSQ
Sbjct: 421 DYPFSQ 426
>gi|218563726 DENN/MADD domain containing 1B isoform 1 [Homo
sapiens]
Length = 755
Score = 791 bits (2043), Expect = 0.0
Identities = 394/417 (94%), Positives = 395/417 (94%), Gaps = 20/417 (4%)
Query: 1 MDCRTKANPDRTFDLVLKVKCHASENEDPVVLWKFPEDFGDQEILQSVPKFCFPFDVERV 60
MDCRTKANPDRTFDLVLKVKCHASENEDPVVLWKFPEDFGDQEILQSVPKFCFPFDVERV
Sbjct: 1 MDCRTKANPDRTFDLVLKVKCHASENEDPVVLWKFPEDFGDQEILQSVPKFCFPFDVERV 60
Query: 61 SQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYLAK 120
SQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYLAK
Sbjct: 61 SQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYLAK 120
Query: 121 ELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTG 180
ELENDLNETLRSLYNHPVPKANTPVNLSV HSYFIAPDVTG
Sbjct: 121 ELENDLNETLRSLYNHPVPKANTPVNLSV--------------------HSYFIAPDVTG 160
Query: 181 LPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMY 240
LPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMY
Sbjct: 161 LPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMY 220
Query: 241 WQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFSDL 300
WQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFSDL
Sbjct: 221 WQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFSDL 280
Query: 301 NNLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEESF 360
NNLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEESF
Sbjct: 281 NNLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEESF 340
Query: 361 VKHRSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGGKDK 417
VKHRSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGG +
Sbjct: 341 VKHRSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGGNPR 397
>gi|55749789 DENN/MADD domain containing 1A isoform 2 [Homo sapiens]
Length = 559
Score = 550 bits (1417), Expect = e-157
Identities = 276/425 (64%), Positives = 328/425 (77%), Gaps = 24/425 (5%)
Query: 1 MDCRTKANPDRTFDLVLKVKCHASEN--EDPVVLWKFPEDFGDQEILQSVPKFCFPFDVE 58
M R K NP+ TF++ ++V + DP V +FPED+ DQE+LQ++ KFCFPF V+
Sbjct: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
Query: 59 RVSQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYL 118
++ +QVGQ+FTFVLTDI+SKQRFGFCRL+SG C CILSYLPWFEV+YKLLN LADY
Sbjct: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
Query: 119 AKELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDV 178
K EN NE L +L+ P+P V+LSV HSYF PD
Sbjct: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSV--------------------HSYFTVPDT 160
Query: 179 TGLPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYP 238
LP+IPE+RNLTEYFVAVDVNNML LYASML+ERRI+II SKLSTLTACIHGSAA+LYP
Sbjct: 161 RELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYP 220
Query: 239 MYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFS 298
MYWQH+YIPVLPPHLLDYCCAPMPYLIGIH SL+E+V+N +L+DVV+LNVDTNTLE+PF
Sbjct: 221 MYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFD 280
Query: 299 DLNNLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEE 358
DL +LP+DV+S+LKN+LKK ST TGDGVARAFL+AQAA FGSYR+AL+ +P EPITFCEE
Sbjct: 281 DLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEE 340
Query: 359 SFVKH-RSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGGKDK 417
+FV H RS M+QFL+ A LQLFKQFIDGRL LN+G GFSDVFEEEI G + G DK
Sbjct: 341 AFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEY-AGSDK 399
Query: 418 LQYDY 422
L + +
Sbjct: 400 LYHQW 404
>gi|55749779 DENN/MADD domain containing 1A isoform 1 [Homo sapiens]
Length = 1009
Score = 550 bits (1417), Expect = e-157
Identities = 276/425 (64%), Positives = 328/425 (77%), Gaps = 24/425 (5%)
Query: 1 MDCRTKANPDRTFDLVLKVKCHASEN--EDPVVLWKFPEDFGDQEILQSVPKFCFPFDVE 58
M R K NP+ TF++ ++V + DP V +FPED+ DQE+LQ++ KFCFPF V+
Sbjct: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
Query: 59 RVSQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYL 118
++ +QVGQ+FTFVLTDI+SKQRFGFCRL+SG C CILSYLPWFEV+YKLLN LADY
Sbjct: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
Query: 119 AKELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDV 178
K EN NE L +L+ P+P V+LSV HSYF PD
Sbjct: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSV--------------------HSYFTVPDT 160
Query: 179 TGLPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYP 238
LP+IPE+RNLTEYFVAVDVNNML LYASML+ERRI+II SKLSTLTACIHGSAA+LYP
Sbjct: 161 RELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYP 220
Query: 239 MYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFS 298
MYWQH+YIPVLPPHLLDYCCAPMPYLIGIH SL+E+V+N +L+DVV+LNVDTNTLE+PF
Sbjct: 221 MYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFD 280
Query: 299 DLNNLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEE 358
DL +LP+DV+S+LKN+LKK ST TGDGVARAFL+AQAA FGSYR+AL+ +P EPITFCEE
Sbjct: 281 DLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEE 340
Query: 359 SFVKH-RSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGGKDK 417
+FV H RS M+QFL+ A LQLFKQFIDGRL LN+G GFSDVFEEEI G + G DK
Sbjct: 341 AFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEY-AGSDK 399
Query: 418 LQYDY 422
L + +
Sbjct: 400 LYHQW 404
>gi|113205087 DENN/MADD domain containing 1C [Homo sapiens]
Length = 801
Score = 445 bits (1144), Expect = e-125
Identities = 222/417 (53%), Positives = 289/417 (69%), Gaps = 3/417 (0%)
Query: 1 MDCRTKANPDRTFDLVLKVKCHASENEDPVVLWKFPEDFGDQEILQSVPKFCFPFDVERV 60
M+ R + FD + C AS EDP +L +FP DF DQE +Q VPKFCFPFDVER
Sbjct: 1 MESRAEGGSPAVFDWFFEAACPASLQEDPPILRQFPPDFRDQEAMQMVPKFCFPFDVERE 60
Query: 61 SQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYLAK 120
+ QHFTF LTD+ +RFGFCRL +G CLCILS+LPWFEV+YKLLNT+ D LA+
Sbjct: 61 PPSPAVQHFTFALTDLAGNRRFGFCRLRAGTQSCLCILSHLPWFEVFYKLLNTVGDLLAQ 120
Query: 121 ELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPA--LVPHSYFIAPDV 178
+ + E L++L+ + V L + + ++ Q + P S F+APD
Sbjct: 121 DQVTEAEELLQNLFQQSLSGPQASVGLELGSGVTVSSGQGIPPPTRGNSKPLSCFVAPDS 180
Query: 179 TGLPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYP 238
LP+IPE+RNLTE VAV N++ L+A++L ERR+++ +SKLSTLT+C+H S ALLYP
Sbjct: 181 GRLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTASKLSTLTSCVHASCALLYP 240
Query: 239 MYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFS 298
M W+H+ IP LPPHLLDYCCAPMPYLIG+H+SL ERV+ K+LEDVV+LNVD NTLE+ F+
Sbjct: 241 MRWEHVLIPTLPPHLLDYCCAPMPYLIGVHASLAERVREKALEDVVVLNVDANTLETTFN 300
Query: 299 DLNNLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEE 358
D+ LP DVVS L+ +L+K + A G+GV+R FL+AQA LFG YRDAL PG+P+TF EE
Sbjct: 301 DVQALPPDVVSLLRLRLRKVALAPGEGVSRLFLKAQALLFGGYRDALVCSPGQPVTFSEE 360
Query: 359 SFVKHR-SSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGG 414
F+ + + ++ F A++LQLFKQFI+ RL KLN G GFSD FE+EIT G G
Sbjct: 361 VFLAQKPGAPLQAFHRRAVHLQLFKQFIEARLEKLNKGEGFSDQFEQEITGCGASSG 417
>gi|154813195 DENN/MADD domain containing 2A [Homo sapiens]
Length = 1009
Score = 143 bits (361), Expect = 3e-34
Identities = 116/401 (28%), Positives = 195/401 (48%), Gaps = 47/401 (11%)
Query: 33 WKFPEDFGDQEILQSVPKFCFPFDVERVSQNQ-VGQHFTFVLTDIESKQRFGFCR-LTSG 90
+KF + DQ L+++P+FCFP + V Q + F+FVLT + +RFG+CR L G
Sbjct: 598 FKFMREAEDQ--LKAIPQFCFPDAKDWVPVQQFTSETFSFVLTGEDGSRRFGYCRRLLPG 655
Query: 91 GT-----ICLCILSYLPWFEVYYKLLNTLADYLAKELENDLNETLRSLYNHPVPKANTPV 145
G CI+S L F ++ ++L+ + E R + P P+
Sbjct: 656 GKGKRLPEVYCIVSRLGCFSLFSRILDEV-------------EKRRGIS----PALVQPL 698
Query: 146 NLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLPTIPESRNLTEYFVAVDVNNMLQL 205
SV + F A + + + L + L + E + F ++ V +++ +
Sbjct: 699 MRSVMEAPFPALGKTILVKNFLPGSGTEVIELCRPLDSRLEHVDFESLFSSLSVRHLVCV 758
Query: 206 YASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLI 265
+AS+L ERR++ I+ KLS L+ C H AL+YP WQH YIPVLPP ++D C+P P+LI
Sbjct: 759 FASLLLERRVIFIADKLSILSKCCHAMVALIYPFAWQHTYIPVLPPAMVDIVCSPTPFLI 818
Query: 266 GIHSSLIERVKNKSLEDVVMLN-VDTNTLESPFSDLNNLPSDVVSALKNKLKK------- 317
G+ SS + ++ LE+V++++ V++ L + + LP + AL++ L++
Sbjct: 819 GLLSSSLPLLRELPLEEVLVVDLVNSRFLRQMDDEDSILPRKLQVALEHILEQRNELACE 878
Query: 318 ------------QSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEESFVKHRS 365
+S+ + V+ AF+R + G Y L E T E+F K S
Sbjct: 879 QDEGPLDGRHGPESSPLNEVVSEAFVRFFVEIVGHYSLFLTSGEREERTLQREAFRKAVS 938
Query: 366 S-VMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEE 405
S ++ FLE + Q+F+ FI R + +G +V +E
Sbjct: 939 SKSLRHFLEVFMETQMFRGFIQERELRRQDAKGLFEVRAQE 979
>gi|21361991 DENN/MADD domain containing 2D [Homo sapiens]
Length = 471
Score = 135 bits (340), Expect = 7e-32
Identities = 115/425 (27%), Positives = 202/425 (47%), Gaps = 62/425 (14%)
Query: 15 LVLKVKCHASENE-DPVVLWKFPEDF----GDQE----ILQSVPKFCFPFDVERVSQNQV 65
LV+ +K SE++ +P++ ++FP+ G QE +L+++P FCFP E S +
Sbjct: 58 LVVSLKKKRSEDDYEPIITYQFPKRENLLRGQQEEEERLLKAIPLFCFPDGNEWASLTEY 117
Query: 66 GQH-FTFVLTDIESKQRFGFCR--LTSGGTICL----CILSYLPWFEVYYKLLNTLADYL 118
+ F+FVLT+++ ++ G+CR L +G L CI+S + F ++ K+L+
Sbjct: 118 PRETFSFVLTNVDGSRKIGYCRRLLPAGPGPRLPKVYCIISCIGCFGLFSKILD------ 171
Query: 119 AKELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDV 178
E+E ++ +Y P + + F A P PD
Sbjct: 172 --EVEKRHQISMAVIY---------PFMQGLREAAFPA--------PGKTVTLKSFIPD- 211
Query: 179 TGLPTIPESRNLTEYFVAVDVNNML---------QLYASMLHERRIVIISSKLSTLTACI 229
+G I +R L + VD +++L Q++AS + ER+I+ ++ LSTL+ CI
Sbjct: 212 SGTEFISLTRPLDSHLEHVDFSSLLHCLSFEQILQIFASAVLERKIIFLAEGLSTLSQCI 271
Query: 230 HGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVD 289
H +AALLYP W H YIPV+P LL C P P+++G+ + V + +E+V+++N+
Sbjct: 272 HAAAALLYPFSWAHTYIPVVPESLLATVCCPTPFMVGVQMRFQQEVMDSPMEEVLLVNLC 331
Query: 290 TNTLESPFSDLNN-----LPSDVVSALKNKLKKQSTA--TGDGVARAFLRAQAALFGSYR 342
T D + L D++ +L + + TA + V+ F++ + G Y
Sbjct: 332 EGTFLMSVGDEKDILPPKLQDDILDSLGQGINELKTAEQINEHVSGPFVQFFVKIVGHYA 391
Query: 343 DALRYKPGEPITFCEESFVKH-RSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDV 401
++ + F E SF K S ++F++ + QLF FI N G+
Sbjct: 392 SYIKREANGQGHFQERSFCKALTSKTNRRFVKKFVKTQLFSLFIQEAEKSKNPPAGY--- 448
Query: 402 FEEEI 406
F+++I
Sbjct: 449 FQQKI 453
>gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo sapiens]
Length = 1137
Score = 134 bits (338), Expect = 1e-31
Identities = 104/389 (26%), Positives = 186/389 (47%), Gaps = 44/389 (11%)
Query: 42 QEILQSVPKFCFPFDVERVSQNQVGQH-FTFVLTDIESKQRFGFCR--LTSGGTICL--- 95
+E L+++P+FCFP + + ++ F+F+LT + +RFG+CR L SG L
Sbjct: 736 EERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEV 795
Query: 96 -CILSYLPWFEVYYKLLNTLADYLAKELENDLNETLRSLYNHPVPKANTPVNLSVNQEIF 154
C++S L F ++ K+L+ E+E + +Y P S+ + F
Sbjct: 796 YCVISRLGCFGLFSKVLD--------EVERRRGISAALVY---------PFMRSLMESPF 838
Query: 155 IACEQVLKDQPALVPHSYFIAPDVTGLPTIPESRNLTEYFVAVDVNNMLQLYASMLHERR 214
A + +K + L + + + E + F + V +++++AS+L ERR
Sbjct: 839 PAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERR 898
Query: 215 IVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIER 274
++ ++ KLSTL++C H ALLYP WQH +IPVLP ++D C P P+L+G+ SS + +
Sbjct: 899 VIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPK 958
Query: 275 VKNKSLEDVVMLNVDTNTLESPFSDLNN-LPSDVVSALKNKLKKQSTATGDG-------- 325
+K +E+ +M+N+ ++ D + LP + +AL+ L++++
Sbjct: 959 LKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDE 1018
Query: 326 -------VARAFLRAQAALFGSYRDALRYKPGEPITFCEESFVKH-RSSVMKQFLETAIN 377
V+ F+R G Y L F E+F K S +++FLE +
Sbjct: 1019 CNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFME 1078
Query: 378 LQLFKQFIDGRLAKLNAGRGFSDVFEEEI 406
Q+F FI R + +G +FE+ +
Sbjct: 1079 SQMFAGFIQDRELRKCRAKG---LFEQRV 1104
>gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo sapiens]
Length = 1137
Score = 134 bits (338), Expect = 1e-31
Identities = 104/389 (26%), Positives = 186/389 (47%), Gaps = 44/389 (11%)
Query: 42 QEILQSVPKFCFPFDVERVSQNQVGQH-FTFVLTDIESKQRFGFCR--LTSGGTICL--- 95
+E L+++P+FCFP + + ++ F+F+LT + +RFG+CR L SG L
Sbjct: 736 EERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEV 795
Query: 96 -CILSYLPWFEVYYKLLNTLADYLAKELENDLNETLRSLYNHPVPKANTPVNLSVNQEIF 154
C++S L F ++ K+L+ E+E + +Y P S+ + F
Sbjct: 796 YCVISRLGCFGLFSKVLD--------EVERRRGISAALVY---------PFMRSLMESPF 838
Query: 155 IACEQVLKDQPALVPHSYFIAPDVTGLPTIPESRNLTEYFVAVDVNNMLQLYASMLHERR 214
A + +K + L + + + E + F + V +++++AS+L ERR
Sbjct: 839 PAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERR 898
Query: 215 IVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIER 274
++ ++ KLSTL++C H ALLYP WQH +IPVLP ++D C P P+L+G+ SS + +
Sbjct: 899 VIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPK 958
Query: 275 VKNKSLEDVVMLNVDTNTLESPFSDLNN-LPSDVVSALKNKLKKQSTATGDG-------- 325
+K +E+ +M+N+ ++ D + LP + +AL+ L++++
Sbjct: 959 LKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDE 1018
Query: 326 -------VARAFLRAQAALFGSYRDALRYKPGEPITFCEESFVKH-RSSVMKQFLETAIN 377
V+ F+R G Y L F E+F K S +++FLE +
Sbjct: 1019 CNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFME 1078
Query: 378 LQLFKQFIDGRLAKLNAGRGFSDVFEEEI 406
Q+F FI R + +G +FE+ +
Sbjct: 1079 SQMFAGFIQDRELRKCRAKG---LFEQRV 1104
>gi|21264614 suppression of tumorigenicity 5 isoform 2 [Homo
sapiens]
Length = 717
Score = 134 bits (338), Expect = 1e-31
Identities = 104/389 (26%), Positives = 186/389 (47%), Gaps = 44/389 (11%)
Query: 42 QEILQSVPKFCFPFDVERVSQNQVGQH-FTFVLTDIESKQRFGFCR--LTSGGTICL--- 95
+E L+++P+FCFP + + ++ F+F+LT + +RFG+CR L SG L
Sbjct: 316 EERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEV 375
Query: 96 -CILSYLPWFEVYYKLLNTLADYLAKELENDLNETLRSLYNHPVPKANTPVNLSVNQEIF 154
C++S L F ++ K+L+ E+E + +Y P S+ + F
Sbjct: 376 YCVISRLGCFGLFSKVLD--------EVERRRGISAALVY---------PFMRSLMESPF 418
Query: 155 IACEQVLKDQPALVPHSYFIAPDVTGLPTIPESRNLTEYFVAVDVNNMLQLYASMLHERR 214
A + +K + L + + + E + F + V +++++AS+L ERR
Sbjct: 419 PAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERR 478
Query: 215 IVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIER 274
++ ++ KLSTL++C H ALLYP WQH +IPVLP ++D C P P+L+G+ SS + +
Sbjct: 479 VIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPK 538
Query: 275 VKNKSLEDVVMLNVDTNTLESPFSDLNN-LPSDVVSALKNKLKKQSTATGDG-------- 325
+K +E+ +M+N+ ++ D + LP + +AL+ L++++
Sbjct: 539 LKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDE 598
Query: 326 -------VARAFLRAQAALFGSYRDALRYKPGEPITFCEESFVKH-RSSVMKQFLETAIN 377
V+ F+R G Y L F E+F K S +++FLE +
Sbjct: 599 CNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFME 658
Query: 378 LQLFKQFIDGRLAKLNAGRGFSDVFEEEI 406
Q+F FI R + +G +FE+ +
Sbjct: 659 SQMFAGFIQDRELRKCRAKG---LFEQRV 684
>gi|121949817 DENN/MADD domain containing 2C [Homo sapiens]
Length = 871
Score = 124 bits (312), Expect = 1e-28
Identities = 106/408 (25%), Positives = 188/408 (46%), Gaps = 58/408 (14%)
Query: 29 PVVLWKFP--EDFGD------QEILQSVPKFCFPFDVERVSQNQV-GQHFTFVLTDIESK 79
P V+ +FP +D G +E L+ +PKFCFP + + +++ + F+FVLT +
Sbjct: 453 PQVIQQFPGKDDHGYKQSKDMEERLKVIPKFCFPDSKDWMPTSELKSETFSFVLTGEDGS 512
Query: 80 QRFGFCR----LTSGGTI--CLCILSYLPWFEVYYKLLNTLADYLAKELENDL-NETLRS 132
+ FG+C+ + G + C++S L F ++ K+L+ + +E+ L +RS
Sbjct: 513 RWFGYCKKLLPVGKGKRLPEVYCMVSRLGCFNLFSKILDEVEK--RREMSPALVYPFMRS 570
Query: 133 LYNHPVPKANTPVNLS-----VNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLPTIPES 187
+ P P + + E C L + E
Sbjct: 571 VMEAPFPAPGRTITVKSYLPGAGDESIELCRP---------------------LDSRLEH 609
Query: 188 RNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIP 247
+ F + V +++++ AS+L ERR++ +++ LSTL+ C H A LYP WQH YIP
Sbjct: 610 VDFKCLFKCLSVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIP 669
Query: 248 VLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFSDLNN-LPSD 306
VLP ++D C+P P+LIGI S + ++++ +E+V+++++ + SD + LP
Sbjct: 670 VLPASMIDIVCSPTPFLIGILSCSLPQLQDLPIEEVLIVDLCADKFLQEVSDEDEILPPK 729
Query: 307 VVSALKNKLKK------------QSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPIT 354
+ +AL L++ Q V+ AF+R L G Y +
Sbjct: 730 LQAALMQILEERNEILTQEQNFSQDVTLNSLVSEAFVRFFVELVGHYSLNMTVTERGERV 789
Query: 355 FCEESFVK-HRSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDV 401
F E F K H S ++ FL+ + Q+F FI R + + +G ++
Sbjct: 790 FQREPFRKSHTSRSVRHFLDLFMETQMFAGFIQDRELRKSGVKGLFEI 837
>gi|94818781 DENN/MADD domain containing 4C [Homo sapiens]
Length = 1673
Score = 79.3 bits (194), Expect = 6e-15
Identities = 99/425 (23%), Positives = 166/425 (39%), Gaps = 84/425 (19%)
Query: 50 KFCFPFDVERVSQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYK 109
+F P+ E +S+ Q+ H +LT +E K + C+C+LS+ P+FE + K
Sbjct: 38 QFYEPYSRELLSEKQL-MHLG-LLTPVERKM----VSKSINTNKCICLLSHWPFFEAFRK 91
Query: 110 LLNTLADYLAK-----ELENDLNETLRSLYNHPVPKANTP---VNLSVNQEIFIACEQVL 161
L + +E ++ ++++ P P P V LSV+ + ++
Sbjct: 92 FLMFIYKLSVSGPHPLPIEKHISHFMQNI---PFPSPQRPRILVQLSVHDALILS----- 143
Query: 162 KDQPALVPHSYFIAPDVTGLPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSK 221
QP P LP N + + + N L +L E +I++ S +
Sbjct: 144 --QPVSTP-----------LPL--SGANFSTLLMNLGPENCATLLLFVLLESKILLHSLR 188
Query: 222 LSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLE 281
+ LT A+++P WQ YIP+ P L AP+P+++G+ S + + +
Sbjct: 189 PAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFD--LHDPPQ 246
Query: 282 DVVMLNVDTNTL----ESPFSDLNNLPSDVVSALKNKLKK---------QSTATGDG--- 325
DVV +++DTN L E + LP L + LKK Q T G
Sbjct: 247 DVVCIDLDTNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDM 306
Query: 326 -------------------VARAFLRAQAALFGSYRDALR---YKPGEPIT-----FCEE 358
+ AFLR A++ YR LR P T F +
Sbjct: 307 TPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAADSLFDRQ 366
Query: 359 SFVKHRSSVMKQFLETAINLQLFKQFID--GRLAKLNAGRGFSDVFEEEITSGGFCGGKD 416
F+K R +F Q+F +FI+ ++ + G F D E++ D
Sbjct: 367 GFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTD 426
Query: 417 KLQYD 421
K+ +D
Sbjct: 427 KVDFD 431
>gi|29788755 SET binding factor 2 [Homo sapiens]
Length = 1849
Score = 79.0 bits (193), Expect = 8e-15
Identities = 89/413 (21%), Positives = 162/413 (39%), Gaps = 74/413 (17%)
Query: 31 VLWKFPE-DFGDQEILQSVPKFCFPFDVERVSQNQVGQHFTFVLTDIESKQRFGFC---- 85
++ +FP+ D+ D Q + FC P + + + F VLTDI+S + + C
Sbjct: 27 IIQRFPQKDWDDTPFPQGIELFCQPGGWQLSRERKQPTFFVVVLTDIDSDRHYCSCLTFY 86
Query: 86 --RLTSGGTI-----------------------CLCILSYLPWFEVYYKLLNTLADYLAK 120
+ GT L ++S L + E++ L +
Sbjct: 87 EAEINLQGTKKEEIEGEAKVSGLIQPAEVFAPKSLVLVSRLYYPEIFRACLGLIYTVYVD 146
Query: 121 ELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTG 180
L L + +L VP A +Q++F + L+ + +TG
Sbjct: 147 SLNVSLESLIANLCACLVPAAGG------SQKLF----SLGAGDRQLIQTPLHDSLPITG 196
Query: 181 LPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMY 240
++ F + + N+L L+ ++L E +++ S+ L+ +L++P+
Sbjct: 197 T-------SVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLK 249
Query: 241 WQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESP-FSD 299
+ + YIP+LP LL+ +P P++IG+HS + + L DV++ ++D T++ P
Sbjct: 250 YSYPYIPILPAQLLEVLSSPTPFIIGVHS--VFKTDVHELLDVIIADLDGGTIKIPECIH 307
Query: 300 LNNLPSDVVSALKNKLK---------------------KQSTATGDGVARAFLRAQAALF 338
L++LP ++ ++ L S V FLR A LF
Sbjct: 308 LSSLPEPLLHQTQSALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLFAQLF 367
Query: 339 GSYRDAL---RYKPGEPITFCEESFVKHRSSVMKQFLETAINLQLFKQFIDGR 388
YR L R I F + +F+ R V FL ++ F F+ R
Sbjct: 368 QGYRSCLQLIRIHAEPVIHFHKTAFLGQRGLVENDFLTKVLSGMAFAGFVSER 420
>gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo
sapiens]
Length = 1906
Score = 75.5 bits (184), Expect = 9e-14
Identities = 101/437 (23%), Positives = 156/437 (35%), Gaps = 99/437 (22%)
Query: 31 VLWKFP-EDFGDQEILQSVPKFCFPFDVE-----RVSQNQVGQHFTFVLTDIESKQRFGF 84
++ ++P ED+ + +SVP FC P S+ + TFVLT +++ +G
Sbjct: 212 LICRYPQEDYESFSLPESVPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGA 271
Query: 85 C----------------RLTSGGTI---------------CLCILSYLPWFEVYYKLLNT 113
RL G T C+C+LS+ P+F+ + K L
Sbjct: 272 AIQFYEPYSEENLTEKQRLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTF 331
Query: 114 LADYLAKELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYF 173
L Y E S + H VP Q + L PH
Sbjct: 332 LYRYSISGPHVLPIEKHISHFMHKVP---------------FPSPQRPRILVQLSPHDNL 376
Query: 174 IAPDVTGLPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSA 233
I P + + N + L + E +I+I S + S LT+
Sbjct: 377 ILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALV 436
Query: 234 ALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTL 293
++++P +W Y+P+ P L D AP P+++GI S + DV ++VDTNT+
Sbjct: 437 SMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPP--PDVSCVDVDTNTI 494
Query: 294 ESPFSDLNN-----LPSDVVSALKNKL--------KKQSTATGDG--------------- 325
S D N LP L N L K Q DG
Sbjct: 495 -SQIGDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKLQQRPRDDGLMDLAINDYDFNSGK 553
Query: 326 --------VARAFLRAQAALFGSYRDALR---YKPGEPIT-----FCEESFVKHRSSVMK 369
+ AFL A++ YR LR P E T F ++F++ R +
Sbjct: 554 RLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQ 613
Query: 370 QFLETAINLQLFKQFID 386
+F Q+F +FI+
Sbjct: 614 KFYNMMTKTQMFIRFIE 630
>gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo
sapiens]
Length = 1863
Score = 75.5 bits (184), Expect = 9e-14
Identities = 101/437 (23%), Positives = 156/437 (35%), Gaps = 99/437 (22%)
Query: 31 VLWKFP-EDFGDQEILQSVPKFCFPFDVE-----RVSQNQVGQHFTFVLTDIESKQRFGF 84
++ ++P ED+ + +SVP FC P S+ + TFVLT +++ +G
Sbjct: 212 LICRYPQEDYESFSLPESVPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGA 271
Query: 85 C----------------RLTSGGTI---------------CLCILSYLPWFEVYYKLLNT 113
RL G T C+C+LS+ P+F+ + K L
Sbjct: 272 AIQFYEPYSEENLTEKQRLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTF 331
Query: 114 LADYLAKELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYF 173
L Y E S + H VP Q + L PH
Sbjct: 332 LYRYSISGPHVLPIEKHISHFMHKVP---------------FPSPQRPRILVQLSPHDNL 376
Query: 174 IAPDVTGLPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSA 233
I P + + N + L + E +I+I S + S LT+
Sbjct: 377 ILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALV 436
Query: 234 ALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTL 293
++++P +W Y+P+ P L D AP P+++GI S + DV ++VDTNT+
Sbjct: 437 SMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPP--PDVSCVDVDTNTI 494
Query: 294 ESPFSDLNN-----LPSDVVSALKNKL--------KKQSTATGDG--------------- 325
S D N LP L N L K Q DG
Sbjct: 495 -SQIGDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKLQQRPRDDGLMDLAINDYDFNSGK 553
Query: 326 --------VARAFLRAQAALFGSYRDALR---YKPGEPIT-----FCEESFVKHRSSVMK 369
+ AFL A++ YR LR P E T F ++F++ R +
Sbjct: 554 RLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQ 613
Query: 370 QFLETAINLQLFKQFID 386
+F Q+F +FI+
Sbjct: 614 KFYNMMTKTQMFIRFIE 630
>gi|44889475 RAB6 interacting protein 1 [Homo sapiens]
Length = 1287
Score = 73.2 bits (178), Expect = 4e-13
Identities = 37/117 (31%), Positives = 66/117 (56%), Gaps = 4/117 (3%)
Query: 192 EYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPP 251
E F + V N+ QL+ L E +I++ S L AL++P WQH+Y+P+LP
Sbjct: 288 EVFELLGVENVFQLFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPA 347
Query: 252 HLLDYCCAPMPYLIGIHSSLIE---RVKNKSLEDVVMLNVDTNTLESPFSDLNNLPS 305
LL + AP+PYL+G+HS+ ++ +++ ++ +++D + +E P DL P+
Sbjct: 348 SLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDIDNHFIELP-EDLPQFPN 403
>gi|50345870 DENN/MADD domain containing 3 [Homo sapiens]
Length = 1198
Score = 72.4 bits (176), Expect = 7e-13
Identities = 56/220 (25%), Positives = 98/220 (44%), Gaps = 36/220 (16%)
Query: 202 MLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPM 261
+LQ+ +L E+RIV SS + LT A LYP+ WQH ++P+L +LD+ AP
Sbjct: 203 VLQILTCILTEQRIVFFSSDWALLTLVTECFMAYLYPLQWQHPFVPILSDQMLDFVMAPT 262
Query: 262 PYLIGIHSSLIERVKNKSLEDVVMLNVD--TNTLESPFSDLNNLPSDVVSALKNKLKK-- 317
+L+G H E V +K + +V++N+D + T D ++P + A + +++
Sbjct: 263 SFLMGCHLDHFEEV-SKEADGLVLINIDHGSITYSKSTDDNVDIPDVPLLAAQTFIQRVQ 321
Query: 318 --------------QSTATGDG--------------VARAFLRAQAALFGSYRDALRYKP 349
ST +G + + L+ ++F ++ L Y
Sbjct: 322 SLQLHHELHAAHLLSSTDLKEGRAHRRSWQQKLNCQIQQTTLQLLVSIFRDVKNHLNY-- 379
Query: 350 GEPITFCEESFVKHRSSVMKQFLETAINLQLFKQFIDGRL 389
E F E F+K R+ QF + ++ +F F+ RL
Sbjct: 380 -EHRVFNSEEFLKTRAPGDHQFYKQVLDTYMFHSFLKARL 418
>gi|239735519 SET binding factor 1 [Homo sapiens]
Length = 1893
Score = 71.2 bits (173), Expect = 2e-12
Identities = 60/232 (25%), Positives = 104/232 (44%), Gaps = 28/232 (12%)
Query: 183 TIPESR-NLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYW 241
++P SR ++ F + + N+L L+ + L E +++ +S L G ALL+P+ +
Sbjct: 203 SLPVSRCSVALLFRQLGITNVLSLFCAALTEHKVLFLSRSYQRLADACRGLLALLFPLRY 262
Query: 242 QHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESP-FSDL 300
Y+P+LP LL+ P P++IG++++ + + + L DV++ ++D T+ P +
Sbjct: 263 SFTYVPILPAQLLEVLSTPTPFIIGVNAAF--QAETQELLDVIVADLDGGTVTIPECVHI 320
Query: 301 NNLPSDVVSALKNKLK---------------KQSTATG-----DGVARA-FLRAQAALFG 339
LP + S + L +T+T D RA FLR A L
Sbjct: 321 PPLPEPLQSQTHSVLSMVLDPELELADLAFPPPTTSTSSLKMQDKELRAVFLRLFAQLLQ 380
Query: 340 SYR---DALRYKPGEPITFCEESFVKHRSSVMKQFLETAINLQLFKQFIDGR 388
YR +R P I F + +F+ R V FL + F F+ R
Sbjct: 381 GYRWCLHVVRIHPEPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSER 432
Score = 32.3 bits (72), Expect = 0.84
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 1/56 (1%)
Query: 31 VLWKFPE-DFGDQEILQSVPKFCFPFDVERVSQNQVGQHFTFVLTDIESKQRFGFC 85
+L +FPE D+ D Q + FC P + + F VLTDI S++ + C
Sbjct: 27 ILQRFPEKDWEDNPFPQGIELFCQPSGWQLCPERNPPTFFVAVLTDINSERHYCAC 82
>gi|122891862 DENN/MADD domain containing 5B [Homo sapiens]
Length = 1274
Score = 71.2 bits (173), Expect = 2e-12
Identities = 36/112 (32%), Positives = 61/112 (54%), Gaps = 7/112 (6%)
Query: 190 LTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVL 249
L E F + + N++Q++ +L E +I++ S L G LL+P WQH+Y+P+L
Sbjct: 271 LREAFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPIL 330
Query: 250 PPHLLDYCCAPMPYLIGIHSSLIERVKNKSLE-----DVVMLNVDTNTLESP 296
P LL + AP+PYL+G+ S E LE ++ +++D + +E P
Sbjct: 331 PASLLHFLDAPVPYLMGLQSK--EGTDRSKLELPQEANLCFVDIDNHFIELP 380
>gi|148922920 DENN/MADD domain containing 4B [Homo sapiens]
Length = 1496
Score = 69.3 bits (168), Expect = 6e-12
Identities = 61/227 (26%), Positives = 96/227 (42%), Gaps = 46/227 (20%)
Query: 203 LQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMP 262
+ L ++L E ++++ S + LT+ ++++P++WQ YIP+ P L D AP+P
Sbjct: 411 ITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVP 470
Query: 263 YLIGIHSSLIERVKNKSLEDVVMLNVDTNT--------LESPFSDLNNLPSDVVSALKNK 314
+++GIHSS + + DV+ +++DTNT L SP L P V+ A
Sbjct: 471 FIVGIHSSYFD--LHDPPADVICVDLDTNTLFQTEEKKLLSP-RTLPRRPYKVLLATLTN 527
Query: 315 LKKQSTATGDG---------------------------VARAFLRAQAALFGSYRDALRY 347
L +Q T G V AFLR A L YR LR
Sbjct: 528 LYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAFLRFMACLLKGYRVFLRP 587
Query: 348 KPGEPI--------TFCEESFVKHRSSVMKQFLETAINLQLFKQFID 386
P F + F+K R + ++ Q+F QFI+
Sbjct: 588 LTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQLLHTQMFSQFIE 634
>gi|209863002 MAP-kinase activating death domain-containing protein
isoform j [Homo sapiens]
Length = 1541
Score = 55.8 bits (133), Expect = 7e-08
Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 45/261 (17%)
Query: 95 LCILSYLPWFEVYYKLLNTL--------------------------------ADYLAKEL 122
LC+LS+ P+F + + L TL L +E
Sbjct: 177 LCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK 236
Query: 123 ENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLP 182
+ L LR + +PV +S + + I +VL + L P F PD +
Sbjct: 237 SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDI---EVLPQE--LQPALTFALPDPSRFT 291
Query: 183 TIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQ 242
+ +L + VD LQ+ +L E ++V+ S + L+ + A++YP+ +
Sbjct: 292 LVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYM 349
Query: 243 HIYIPVLPPHLL---DYCCAPMPYLIGIHSS-LIERVKNKSLEDVVMLNVDTNTLESPFS 298
IP+LP + AP PY+IG+ +S + ++ K +DV ++++D+N + +P +
Sbjct: 350 FPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN 409
Query: 299 D--LNNLPSDVVSALKNKLKK 317
L LP LK LK+
Sbjct: 410 AEVLPILPEPESLELKKHLKQ 430
>gi|209862998 MAP-kinase activating death domain-containing protein
isoform i [Homo sapiens]
Length = 1544
Score = 55.8 bits (133), Expect = 7e-08
Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 45/261 (17%)
Query: 95 LCILSYLPWFEVYYKLLNTL--------------------------------ADYLAKEL 122
LC+LS+ P+F + + L TL L +E
Sbjct: 177 LCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK 236
Query: 123 ENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLP 182
+ L LR + +PV +S + + I +VL + L P F PD +
Sbjct: 237 SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDI---EVLPQE--LQPALTFALPDPSRFT 291
Query: 183 TIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQ 242
+ +L + VD LQ+ +L E ++V+ S + L+ + A++YP+ +
Sbjct: 292 LVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYM 349
Query: 243 HIYIPVLPPHLL---DYCCAPMPYLIGIHSS-LIERVKNKSLEDVVMLNVDTNTLESPFS 298
IP+LP + AP PY+IG+ +S + ++ K +DV ++++D+N + +P +
Sbjct: 350 FPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN 409
Query: 299 D--LNNLPSDVVSALKNKLKK 317
L LP LK LK+
Sbjct: 410 AEVLPILPEPESLELKKHLKQ 430
>gi|209862994 MAP-kinase activating death domain-containing protein
isoform d [Homo sapiens]
Length = 1647
Score = 55.8 bits (133), Expect = 7e-08
Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 45/261 (17%)
Query: 95 LCILSYLPWFEVYYKLLNTL--------------------------------ADYLAKEL 122
LC+LS+ P+F + + L TL L +E
Sbjct: 177 LCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK 236
Query: 123 ENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLP 182
+ L LR + +PV +S + + I +VL + L P F PD +
Sbjct: 237 SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDI---EVLPQE--LQPALTFALPDPSRFT 291
Query: 183 TIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQ 242
+ +L + VD LQ+ +L E ++V+ S + L+ + A++YP+ +
Sbjct: 292 LVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYM 349
Query: 243 HIYIPVLPPHLL---DYCCAPMPYLIGIHSS-LIERVKNKSLEDVVMLNVDTNTLESPFS 298
IP+LP + AP PY+IG+ +S + ++ K +DV ++++D+N + +P +
Sbjct: 350 FPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN 409
Query: 299 D--LNNLPSDVVSALKNKLKK 317
L LP LK LK+
Sbjct: 410 AEVLPILPEPESLELKKHLKQ 430
>gi|18860873 MAP-kinase activating death domain-containing protein
isoform g [Homo sapiens]
Length = 1581
Score = 55.8 bits (133), Expect = 7e-08
Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 45/261 (17%)
Query: 95 LCILSYLPWFEVYYKLLNTL--------------------------------ADYLAKEL 122
LC+LS+ P+F + + L TL L +E
Sbjct: 177 LCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK 236
Query: 123 ENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLP 182
+ L LR + +PV +S + + I +VL + L P F PD +
Sbjct: 237 SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDI---EVLPQE--LQPALTFALPDPSRFT 291
Query: 183 TIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQ 242
+ +L + VD LQ+ +L E ++V+ S + L+ + A++YP+ +
Sbjct: 292 LVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYM 349
Query: 243 HIYIPVLPPHLL---DYCCAPMPYLIGIHSS-LIERVKNKSLEDVVMLNVDTNTLESPFS 298
IP+LP + AP PY+IG+ +S + ++ K +DV ++++D+N + +P +
Sbjct: 350 FPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN 409
Query: 299 D--LNNLPSDVVSALKNKLKK 317
L LP LK LK+
Sbjct: 410 AEVLPILPEPESLELKKHLKQ 430
>gi|209862987 MAP-kinase activating death domain-containing protein
isoform f [Homo sapiens]
Length = 1479
Score = 55.8 bits (133), Expect = 7e-08
Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 45/261 (17%)
Query: 95 LCILSYLPWFEVYYKLLNTL--------------------------------ADYLAKEL 122
LC+LS+ P+F + + L TL L +E
Sbjct: 177 LCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK 236
Query: 123 ENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLP 182
+ L LR + +PV +S + + I +VL + L P F PD +
Sbjct: 237 SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDI---EVLPQE--LQPALTFALPDPSRFT 291
Query: 183 TIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQ 242
+ +L + VD LQ+ +L E ++V+ S + L+ + A++YP+ +
Sbjct: 292 LVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYM 349
Query: 243 HIYIPVLPPHLL---DYCCAPMPYLIGIHSS-LIERVKNKSLEDVVMLNVDTNTLESPFS 298
IP+LP + AP PY+IG+ +S + ++ K +DV ++++D+N + +P +
Sbjct: 350 FPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN 409
Query: 299 D--LNNLPSDVVSALKNKLKK 317
L LP LK LK+
Sbjct: 410 AEVLPILPEPESLELKKHLKQ 430
>gi|209862983 MAP-kinase activating death domain-containing protein
isoform e [Homo sapiens]
Length = 1608
Score = 55.8 bits (133), Expect = 7e-08
Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 45/261 (17%)
Query: 95 LCILSYLPWFEVYYKLLNTL--------------------------------ADYLAKEL 122
LC+LS+ P+F + + L TL L +E
Sbjct: 177 LCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK 236
Query: 123 ENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLP 182
+ L LR + +PV +S + + I +VL + L P F PD +
Sbjct: 237 SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDI---EVLPQE--LQPALTFALPDPSRFT 291
Query: 183 TIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQ 242
+ +L + VD LQ+ +L E ++V+ S + L+ + A++YP+ +
Sbjct: 292 LVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYM 349
Query: 243 HIYIPVLPPHLL---DYCCAPMPYLIGIHSS-LIERVKNKSLEDVVMLNVDTNTLESPFS 298
IP+LP + AP PY+IG+ +S + ++ K +DV ++++D+N + +P +
Sbjct: 350 FPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN 409
Query: 299 D--LNNLPSDVVSALKNKLKK 317
L LP LK LK+
Sbjct: 410 AEVLPILPEPESLELKKHLKQ 430
>gi|209862979 MAP-kinase activating death domain-containing protein
isoform c [Homo sapiens]
Length = 1545
Score = 55.8 bits (133), Expect = 7e-08
Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 45/261 (17%)
Query: 95 LCILSYLPWFEVYYKLLNTL--------------------------------ADYLAKEL 122
LC+LS+ P+F + + L TL L +E
Sbjct: 177 LCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK 236
Query: 123 ENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLP 182
+ L LR + +PV +S + + I +VL + L P F PD +
Sbjct: 237 SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDI---EVLPQE--LQPALTFALPDPSRFT 291
Query: 183 TIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQ 242
+ +L + VD LQ+ +L E ++V+ S + L+ + A++YP+ +
Sbjct: 292 LVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYM 349
Query: 243 HIYIPVLPPHLL---DYCCAPMPYLIGIHSS-LIERVKNKSLEDVVMLNVDTNTLESPFS 298
IP+LP + AP PY+IG+ +S + ++ K +DV ++++D+N + +P +
Sbjct: 350 FPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN 409
Query: 299 D--LNNLPSDVVSALKNKLKK 317
L LP LK LK+
Sbjct: 410 AEVLPILPEPESLELKKHLKQ 430
>gi|209862975 MAP-kinase activating death domain-containing protein
isoform b [Homo sapiens]
Length = 1565
Score = 55.8 bits (133), Expect = 7e-08
Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 45/261 (17%)
Query: 95 LCILSYLPWFEVYYKLLNTL--------------------------------ADYLAKEL 122
LC+LS+ P+F + + L TL L +E
Sbjct: 177 LCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK 236
Query: 123 ENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLP 182
+ L LR + +PV +S + + I +VL + L P F PD +
Sbjct: 237 SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDI---EVLPQE--LQPALTFALPDPSRFT 291
Query: 183 TIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQ 242
+ +L + VD LQ+ +L E ++V+ S + L+ + A++YP+ +
Sbjct: 292 LVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYM 349
Query: 243 HIYIPVLPPHLL---DYCCAPMPYLIGIHSS-LIERVKNKSLEDVVMLNVDTNTLESPFS 298
IP+LP + AP PY+IG+ +S + ++ K +DV ++++D+N + +P +
Sbjct: 350 FPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN 409
Query: 299 D--LNNLPSDVVSALKNKLKK 317
L LP LK LK+
Sbjct: 410 AEVLPILPEPESLELKKHLKQ 430
>gi|209862971 MAP-kinase activating death domain-containing protein
isoform a [Homo sapiens]
Length = 1588
Score = 55.8 bits (133), Expect = 7e-08
Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 45/261 (17%)
Query: 95 LCILSYLPWFEVYYKLLNTL--------------------------------ADYLAKEL 122
LC+LS+ P+F + + L TL L +E
Sbjct: 177 LCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK 236
Query: 123 ENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLP 182
+ L LR + +PV +S + + I +VL + L P F PD +
Sbjct: 237 SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDI---EVLPQE--LQPALTFALPDPSRFT 291
Query: 183 TIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQ 242
+ +L + VD LQ+ +L E ++V+ S + L+ + A++YP+ +
Sbjct: 292 LVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYM 349
Query: 243 HIYIPVLPPHLL---DYCCAPMPYLIGIHSS-LIERVKNKSLEDVVMLNVDTNTLESPFS 298
IP+LP + AP PY+IG+ +S + ++ K +DV ++++D+N + +P +
Sbjct: 350 FPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN 409
Query: 299 D--LNNLPSDVVSALKNKLKK 317
L LP LK LK+
Sbjct: 410 AEVLPILPEPESLELKKHLKQ 430
>gi|209571517 MAP-kinase activating death domain-containing protein
isoform h [Homo sapiens]
Length = 1587
Score = 55.8 bits (133), Expect = 7e-08
Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 45/261 (17%)
Query: 95 LCILSYLPWFEVYYKLLNTL--------------------------------ADYLAKEL 122
LC+LS+ P+F + + L TL L +E
Sbjct: 177 LCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK 236
Query: 123 ENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLP 182
+ L LR + +PV +S + + I +VL + L P F PD +
Sbjct: 237 SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDI---EVLPQE--LQPALTFALPDPSRFT 291
Query: 183 TIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQ 242
+ +L + VD LQ+ +L E ++V+ S + L+ + A++YP+ +
Sbjct: 292 LVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYM 349
Query: 243 HIYIPVLPPHLL---DYCCAPMPYLIGIHSS-LIERVKNKSLEDVVMLNVDTNTLESPFS 298
IP+LP + AP PY+IG+ +S + ++ K +DV ++++D+N + +P +
Sbjct: 350 FPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN 409
Query: 299 D--LNNLPSDVVSALKNKLKK 317
L LP LK LK+
Sbjct: 410 AEVLPILPEPESLELKKHLKQ 430
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,797,028
Number of Sequences: 37866
Number of extensions: 670009
Number of successful extensions: 1663
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1568
Number of HSP's gapped (non-prelim): 62
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.