BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sapiens] (619 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 1225 0.0 gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 268 1e-71 gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 266 3e-71 gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 249 4e-66 gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 242 8e-64 gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 242 8e-64 gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 239 4e-63 gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 239 5e-63 gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 239 5e-63 gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 238 2e-62 gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 238 2e-62 gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 238 2e-62 gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 232 9e-61 gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 230 3e-60 gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 230 3e-60 gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 220 3e-57 gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 217 2e-56 gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 217 2e-56 gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 208 1e-53 gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 204 1e-52 gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 204 2e-52 gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 204 3e-52 gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 196 4e-50 gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 196 4e-50 gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 196 7e-50 gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 188 1e-47 gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 188 1e-47 gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi... 181 2e-45 gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ... 181 2e-45 gi|4758112 HLA-B associated transcript 1 [Homo sapiens] 179 5e-45 >gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sapiens] Length = 619 Score = 1225 bits (3169), Expect = 0.0 Identities = 619/619 (100%), Positives = 619/619 (100%) Query: 1 MFVPRSLKIKRNANDDGKSCVAKIIKPDPEDLQLDKSRDVPVDAVATEAATIDRHISESC 60 MFVPRSLKIKRNANDDGKSCVAKIIKPDPEDLQLDKSRDVPVDAVATEAATIDRHISESC Sbjct: 1 MFVPRSLKIKRNANDDGKSCVAKIIKPDPEDLQLDKSRDVPVDAVATEAATIDRHISESC 60 Query: 61 PFPSPGGQLAEVHSVSPEQGAKDSHPSEEPVKSFSKTQRWAEPGEPICVVCGRYGEYICD 120 PFPSPGGQLAEVHSVSPEQGAKDSHPSEEPVKSFSKTQRWAEPGEPICVVCGRYGEYICD Sbjct: 61 PFPSPGGQLAEVHSVSPEQGAKDSHPSEEPVKSFSKTQRWAEPGEPICVVCGRYGEYICD 120 Query: 121 KTDEDVCSLECKAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQED 180 KTDEDVCSLECKAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQED Sbjct: 121 KTDEDVCSLECKAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQED 180 Query: 181 QIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLG 240 QIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLG Sbjct: 181 QIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLG 240 Query: 241 RDILASADTGSGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPR 300 RDILASADTGSGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPR Sbjct: 241 RDILASADTGSGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPR 300 Query: 301 MKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLK 360 MKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLK Sbjct: 301 MKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLK 360 Query: 361 MGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQI 420 MGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQI Sbjct: 361 MGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQI 420 Query: 421 ILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKS 480 ILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKS Sbjct: 421 ILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKS 480 Query: 481 QIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLG 540 QIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLG Sbjct: 481 QIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLG 540 Query: 541 QNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLV 600 QNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLV Sbjct: 541 QNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLV 600 Query: 601 TGANLMDIIRKHDKSNSQK 619 TGANLMDIIRKHDKSNSQK Sbjct: 601 TGANLMDIIRKHDKSNSQK 619 >gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens] Length = 1031 Score = 268 bits (684), Expect = 1e-71 Identities = 156/441 (35%), Positives = 258/441 (58%), Gaps = 13/441 (2%) Query: 144 EKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLKQQL-GILVQGQEVTRPI 202 ++ KL P P ++ Y E P + + ++++ + ++ GI V+G+ +PI Sbjct: 313 KQRKLLEPVDHGKIEYEPFRKNF-YVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPI 371 Query: 203 IDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVI 262 + C + + ++LKK GYE PTPIQ Q IP + GRD++ A TGSGKT AFLLP+ Sbjct: 372 KSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMF 431 Query: 263 -----MRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLY 317 R+L E + P A+I+TPTRELA+QI ++ K+ L ++ V + GG + Q+ Sbjct: 432 RHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLG-LRVVCVYGGTGISEQIA 490 Query: 318 RLQQHVKVIIATPGRLLDIIKQSS---VELCGVKIVVVDEADTMLKMGFQQQVLDILENI 374 L++ ++I+ TPGR++D++ +S L V VV+DEAD M MGF+ QV+ I++N+ Sbjct: 491 ELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNV 550 Query: 375 PNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLF 434 D QT++ SAT P ++E LA ++L P+ + G +++ C++V Q ++ +E+ K KL Sbjct: 551 RPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLL 610 Query: 435 EILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEG 494 E+L + V++FVD + AD L + + + + +S+H Q +R +I+ G Sbjct: 611 ELLGHYQE-SGSVIIFVDKQEHADGLLKDLMRAS-YPCMSLHGGIDQYDRDSIINDFKNG 668 Query: 495 DYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSK 554 +++V+T V RGLD+ + LVVN+ P+ ++YVH+ GR GR G G A TFI + Sbjct: 669 TCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQA 728 Query: 555 RLFWDIAKRVKPTGSILPPQL 575 R DI K ++ +G+ +PP L Sbjct: 729 RYAGDIIKALELSGTAVPPDL 749 >gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapiens] Length = 820 Score = 266 bits (681), Expect = 3e-71 Identities = 152/430 (35%), Positives = 248/430 (57%), Gaps = 40/430 (9%) Query: 186 KQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILA 245 ++ I +G ++ PI ++ SLP + + K GY+ PTPIQ Q IP+GL RDI+ Sbjct: 374 REDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIG 433 Query: 246 SADTGSGKTAAFLLPVIM---------RALFESKTPSALILTPTRELAIQIERQAKELMS 296 A+TGSGKTAAFL+P+++ R + P A+IL PTRELA QIE + + Sbjct: 434 VAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGK 493 Query: 297 GLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEAD 356 L ++TV ++GG+ Q +RL+ +++IATPGRL+D+++ + L VV+DEAD Sbjct: 494 PL-GIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEAD 552 Query: 357 TMLKMGFQQQVLDILENIP--------------------------NDCQTILVSATIPTS 390 M+ MGF+ V ILE++P QT++ +AT+P + Sbjct: 553 RMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPA 612 Query: 391 IEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFKPPVLVF 450 +E+LA L P + G P V Q + + + K+KKL IL ++ F PP+++F Sbjct: 613 VERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAIL--EQGFDPPIIIF 670 Query: 451 VDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLD 510 V+ K G D+L+++++K+ G + ++H K Q +R+ L L G +++V+T V GRG+D Sbjct: 671 VNQKKGCDVLAKSLEKM-GYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGID 729 Query: 511 LISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRV-KPTGS 569 + V +VVN+DM ++++Y+H+IGR GR G++G AITF+ +F+++ + + + S Sbjct: 730 IQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVS 789 Query: 570 ILPPQLLNSP 579 PP+L N P Sbjct: 790 SCPPELANHP 799 >gi|21071032 DEAD-box protein abstrakt [Homo sapiens] Length = 622 Score = 249 bits (637), Expect = 4e-66 Identities = 157/472 (33%), Positives = 245/472 (51%), Gaps = 37/472 (7%) Query: 121 KTDEDVCSLECKAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQED 180 K +E + + + L+ VKE + +P K P ++L++ E+ Sbjct: 111 KEEEKILESVAEGRALMSVKEMAKGITYDDPIKTSWTPPR------------YVLSMSEE 158 Query: 181 QIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLG 240 + E ++++ ILV+G + PI F+ P + LKK G PTPIQ+Q IP L G Sbjct: 159 RHERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSG 218 Query: 241 RDILASADTGSGKTAAFLLPVIMRALFESKT--------PSALILTPTRELAIQ----IE 288 RD++ A TGSGKT F LPVIM L + K P LI+ P+RELA Q +E Sbjct: 219 RDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILE 278 Query: 289 RQAKELMS-GLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGV 347 + L P ++ L +GG+ + Q+ ++ V +++ATPGRL+D++++ V L Sbjct: 279 YYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDIC 338 Query: 348 KIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIIT 407 + + +DEAD M+ MGF+ + I QT+L SAT+P I+ A L PV I Sbjct: 339 RYLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 398 Query: 408 GEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKI 467 G +V Q + +V++ AK L E L PPVL+F + K D + E + + Sbjct: 399 GRAGAASLDVIQEVEYVKEEAKMVYLLECLQKT---PPPVLIFAEKKADVDAIHEYL-LL 454 Query: 468 TGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMD 527 G+++++IH K Q ER ++ EG +V+V+T V +GLD +++ V+N+DMP ++ Sbjct: 455 KGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIE 514 Query: 528 EYVHQIGRVGRLGQNGTAITFINN--------NSKRLFWDIAKRVKPTGSIL 571 YVH+IGR GR G G A TFIN + K L + ++V P +L Sbjct: 515 NYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVL 566 >gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] Length = 731 Score = 242 bits (617), Expect = 8e-64 Identities = 146/426 (34%), Positives = 232/426 (54%), Gaps = 10/426 (2%) Query: 159 ESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVT-RPIIDFEHCSLPEVLNHN 217 E P Y EHP + L +++ L+++ I V+G +V +P+ F H + P+ + Sbjct: 126 ELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDV 185 Query: 218 LKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRA-----LFESKTP 272 L + PTPIQ Q P+ L GRD++ A TGSGKT A+LLP I+ L P Sbjct: 186 LMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGP 245 Query: 273 SALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGR 332 L+L PTRELA Q+++ A + R+K+ + GG P PQ+ L++ V++ IATPGR Sbjct: 246 ICLVLAPTRELAQQVQQVADDY-GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGR 304 Query: 333 LLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIE 392 L+D ++ L +V+DEAD ML MGF+ Q+ I++ I D QT++ SAT P + Sbjct: 305 LIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVR 364 Query: 393 QLASQLLHNPVRIITGEKNLPC-ANVRQIILWVEDPAKKKKLFEILNDKKLFKP-PVLVF 450 QLA L + +I G L N+ QI+ + K KL +++ + K ++F Sbjct: 365 QLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIF 424 Query: 451 VDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLD 510 V+ K D L+ +++ G ++ IH +KSQ ER +L G ++++T V RGLD Sbjct: 425 VETKRRCDDLTRRMRR-DGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLD 483 Query: 511 LISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTGSI 570 + V+ V+N+D P+S ++YVH+IGR R GTA TF + + ++ K ++ Sbjct: 484 VEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQA 543 Query: 571 LPPQLL 576 + P+L+ Sbjct: 544 INPKLM 549 >gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] Length = 729 Score = 242 bits (617), Expect = 8e-64 Identities = 146/426 (34%), Positives = 232/426 (54%), Gaps = 10/426 (2%) Query: 159 ESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVT-RPIIDFEHCSLPEVLNHN 217 E P Y EHP + L +++ L+++ I V+G +V +P+ F H + P+ + Sbjct: 126 ELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDV 185 Query: 218 LKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRA-----LFESKTP 272 L + PTPIQ Q P+ L GRD++ A TGSGKT A+LLP I+ L P Sbjct: 186 LMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGP 245 Query: 273 SALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGR 332 L+L PTRELA Q+++ A + R+K+ + GG P PQ+ L++ V++ IATPGR Sbjct: 246 ICLVLAPTRELAQQVQQVADDY-GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGR 304 Query: 333 LLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIE 392 L+D ++ L +V+DEAD ML MGF+ Q+ I++ I D QT++ SAT P + Sbjct: 305 LIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVR 364 Query: 393 QLASQLLHNPVRIITGEKNLPC-ANVRQIILWVEDPAKKKKLFEILNDKKLFKP-PVLVF 450 QLA L + +I G L N+ QI+ + K KL +++ + K ++F Sbjct: 365 QLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIF 424 Query: 451 VDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLD 510 V+ K D L+ +++ G ++ IH +KSQ ER +L G ++++T V RGLD Sbjct: 425 VETKRRCDDLTRRMRR-DGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLD 483 Query: 511 LISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTGSI 570 + V+ V+N+D P+S ++YVH+IGR R GTA TF + + ++ K ++ Sbjct: 484 VEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQA 543 Query: 571 LPPQLL 576 + P+L+ Sbjct: 544 INPKLM 549 >gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] Length = 614 Score = 239 bits (611), Expect = 4e-63 Identities = 146/428 (34%), Positives = 231/428 (53%), Gaps = 15/428 (3%) Query: 159 ESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNL 218 E P Y+EHP + ++E ++ I V+G +P+++F + P + + Sbjct: 50 ELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVI 109 Query: 219 KKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRA-----LFESKTPS 273 + + PT IQ Q PV L G D++ A TGSGKT ++LLP I+ L P Sbjct: 110 ARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPI 169 Query: 274 ALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRL 333 L+L PTRELA Q+++ A E R+K+ + GG P PQ+ L++ V++ IATPGRL Sbjct: 170 CLVLAPTRELAQQVQQVAAEYCRAC-RLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 228 Query: 334 LDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIEQ 393 +D ++ L +V+DEAD ML MGF+ Q+ I++ I D QT++ SAT P + Q Sbjct: 229 IDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQ 288 Query: 394 LASQLLHNPVRIITGEKNLPC-ANVRQIILWVEDPAKKKKLF----EILNDKKLFKPPVL 448 LA L + + I G L N+ QI+ D K +KL EI+++K + + Sbjct: 289 LAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEK---ENKTI 345 Query: 449 VFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRG 508 VFV+ K D L+ +++ G ++ IH +KSQ ER +L G ++++T V RG Sbjct: 346 VFVETKRRCDELTRKMRR-DGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRG 404 Query: 509 LDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTG 568 LD+ V+ V+N+D P+S ++Y+H+IGR R + GTA TF N+ + D+ ++ Sbjct: 405 LDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREAN 464 Query: 569 SILPPQLL 576 + P+LL Sbjct: 465 QAINPKLL 472 >gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] Length = 938 Score = 239 bits (610), Expect = 5e-63 Identities = 152/460 (33%), Positives = 240/460 (52%), Gaps = 17/460 (3%) Query: 156 SEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN 215 SE + P Y EH I NL Q+ +L+ +L + V G RP F H E L Sbjct: 206 SEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLM 265 Query: 216 HNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESKT---- 271 H ++KS Y PTPIQ Q +PV L GRD++ A TGSGKTAAF+ P+++ + + + Sbjct: 266 HQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGD 325 Query: 272 -PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATP 330 P A+I+ PTREL QI + K +++V + GG + Q LQ+ ++++ TP Sbjct: 326 GPIAVIVCPTRELCQQIHAECKRFGKAY-NLRSVAVYGGGSMWEQAKALQEGAEIVVCTP 384 Query: 331 GRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTS 390 GRL+D +K+ + L V +V DEAD M MGF+ QV I ++ D QT+L SAT Sbjct: 385 GRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKK 444 Query: 391 IEQLASQLLHNPVRIITGEKNLPCANVRQII-LWVEDPAK----KKKLFEILNDKKLFKP 445 IE+LA +L +P+R++ G+ +V QI+ + P+K ++L E + Sbjct: 445 IEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGS---- 500 Query: 446 PVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVL 505 VL+FV K A+ L+ + K G +H + Q ER ++ + D V+V+T V Sbjct: 501 -VLLFVTKKANAEELANNL-KQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558 Query: 506 GRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVK 565 RGLD+ S++ V+N+D+ +D + H+IGR GR G+ G A T + D+ + ++ Sbjct: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLE 618 Query: 566 PTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLVTGANL 605 + +LL+ + RK + K + + + G L Sbjct: 619 GANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGL 658 >gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] Length = 938 Score = 239 bits (610), Expect = 5e-63 Identities = 152/460 (33%), Positives = 240/460 (52%), Gaps = 17/460 (3%) Query: 156 SEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN 215 SE + P Y EH I NL Q+ +L+ +L + V G RP F H E L Sbjct: 206 SEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLM 265 Query: 216 HNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESKT---- 271 H ++KS Y PTPIQ Q +PV L GRD++ A TGSGKTAAF+ P+++ + + + Sbjct: 266 HQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGD 325 Query: 272 -PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATP 330 P A+I+ PTREL QI + K +++V + GG + Q LQ+ ++++ TP Sbjct: 326 GPIAVIVCPTRELCQQIHAECKRFGKAY-NLRSVAVYGGGSMWEQAKALQEGAEIVVCTP 384 Query: 331 GRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTS 390 GRL+D +K+ + L V +V DEAD M MGF+ QV I ++ D QT+L SAT Sbjct: 385 GRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKK 444 Query: 391 IEQLASQLLHNPVRIITGEKNLPCANVRQII-LWVEDPAK----KKKLFEILNDKKLFKP 445 IE+LA +L +P+R++ G+ +V QI+ + P+K ++L E + Sbjct: 445 IEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGS---- 500 Query: 446 PVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVL 505 VL+FV K A+ L+ + K G +H + Q ER ++ + D V+V+T V Sbjct: 501 -VLLFVTKKANAEELANNL-KQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558 Query: 506 GRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVK 565 RGLD+ S++ V+N+D+ +D + H+IGR GR G+ G A T + D+ + ++ Sbjct: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLE 618 Query: 566 PTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLVTGANL 605 + +LL+ + RK + K + + + G L Sbjct: 619 GANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGL 658 >gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 [Homo sapiens] Length = 724 Score = 238 bits (606), Expect = 2e-62 Identities = 150/427 (35%), Positives = 241/427 (56%), Gaps = 24/427 (5%) Query: 141 EKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTR 200 E E S P+ P P + ++ + +N D+ + + + V G + Sbjct: 232 EGGESSDTQGPKVTYIPPPPPEDEDSIFAHYQTGINF--DKYDTILVE----VSGHDAPP 285 Query: 201 PIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLP 260 I+ FE +L + LN+N+ K+GY TP+Q IP+ L GRD++A A TGSGKTAAFLLP Sbjct: 286 AILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLP 345 Query: 261 VIMRALFESKT---------PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLP 311 ++ + + T P +I+ PTREL QI +A++ G ++ V++ GG Sbjct: 346 ILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTC-VRAVVIYGGTQ 404 Query: 312 LPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDIL 371 L + ++ Q ++ ATPGRL+DII + + L +K +V+DEAD ML MGF ++ ++ Sbjct: 405 LGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 464 Query: 372 E--NIPN--DCQTILVSATIPTSIEQLASQLLH-NPVRIITGEKNLPCANVRQIILWVED 426 +P+ QT++ SAT P I++LA++ L N + + G+ C +V+Q +L V Sbjct: 465 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQ 524 Query: 427 PAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKN 486 +K++KL EIL + + +VFV+ K AD ++ + + + + SIH ++ Q ER+ Sbjct: 525 FSKREKLVEIL--RNIGDERTMVFVETKKKADFIATFLCQ-EKISTTSIHGDREQREREQ 581 Query: 487 ILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAI 546 L G V+V+T V RGLD+ +V+ V+NFD+PS++DEYVH+IGR GR G G AI Sbjct: 582 ALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAI 641 Query: 547 TFINNNS 553 +F + S Sbjct: 642 SFFDLES 648 >gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [Homo sapiens] Length = 724 Score = 238 bits (606), Expect = 2e-62 Identities = 150/427 (35%), Positives = 241/427 (56%), Gaps = 24/427 (5%) Query: 141 EKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTR 200 E E S P+ P P + ++ + +N D+ + + + V G + Sbjct: 232 EGGESSDTQGPKVTYIPPPPPEDEDSIFAHYQTGINF--DKYDTILVE----VSGHDAPP 285 Query: 201 PIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLP 260 I+ FE +L + LN+N+ K+GY TP+Q IP+ L GRD++A A TGSGKTAAFLLP Sbjct: 286 AILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLP 345 Query: 261 VIMRALFESKT---------PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLP 311 ++ + + T P +I+ PTREL QI +A++ G ++ V++ GG Sbjct: 346 ILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTC-VRAVVIYGGTQ 404 Query: 312 LPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDIL 371 L + ++ Q ++ ATPGRL+DII + + L +K +V+DEAD ML MGF ++ ++ Sbjct: 405 LGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 464 Query: 372 E--NIPN--DCQTILVSATIPTSIEQLASQLLH-NPVRIITGEKNLPCANVRQIILWVED 426 +P+ QT++ SAT P I++LA++ L N + + G+ C +V+Q +L V Sbjct: 465 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQ 524 Query: 427 PAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKN 486 +K++KL EIL + + +VFV+ K AD ++ + + + + SIH ++ Q ER+ Sbjct: 525 FSKREKLVEIL--RNIGDERTMVFVETKKKADFIATFLCQ-EKISTTSIHGDREQREREQ 581 Query: 487 ILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAI 546 L G V+V+T V RGLD+ +V+ V+NFD+PS++DEYVH+IGR GR G G AI Sbjct: 582 ALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAI 641 Query: 547 TFINNNS 553 +F + S Sbjct: 642 SFFDLES 648 >gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 [Homo sapiens] Length = 690 Score = 238 bits (606), Expect = 2e-62 Identities = 150/427 (35%), Positives = 241/427 (56%), Gaps = 24/427 (5%) Query: 141 EKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTR 200 E E S P+ P P + ++ + +N D+ + + + V G + Sbjct: 198 EGGESSDTQGPKVTYIPPPPPEDEDSIFAHYQTGINF--DKYDTILVE----VSGHDAPP 251 Query: 201 PIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLP 260 I+ FE +L + LN+N+ K+GY TP+Q IP+ L GRD++A A TGSGKTAAFLLP Sbjct: 252 AILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLP 311 Query: 261 VIMRALFESKT---------PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLP 311 ++ + + T P +I+ PTREL QI +A++ G ++ V++ GG Sbjct: 312 ILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTC-VRAVVIYGGTQ 370 Query: 312 LPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDIL 371 L + ++ Q ++ ATPGRL+DII + + L +K +V+DEAD ML MGF ++ ++ Sbjct: 371 LGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 430 Query: 372 E--NIPN--DCQTILVSATIPTSIEQLASQLLH-NPVRIITGEKNLPCANVRQIILWVED 426 +P+ QT++ SAT P I++LA++ L N + + G+ C +V+Q +L V Sbjct: 431 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQ 490 Query: 427 PAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKN 486 +K++KL EIL + + +VFV+ K AD ++ + + + + SIH ++ Q ER+ Sbjct: 491 FSKREKLVEIL--RNIGDERTMVFVETKKKADFIATFLCQ-EKISTTSIHGDREQREREQ 547 Query: 487 ILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAI 546 L G V+V+T V RGLD+ +V+ V+NFD+PS++DEYVH+IGR GR G G AI Sbjct: 548 ALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAI 607 Query: 547 TFINNNS 553 +F + S Sbjct: 608 SFFDLES 614 >gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo sapiens] Length = 662 Score = 232 bits (591), Expect = 9e-61 Identities = 144/417 (34%), Positives = 230/417 (55%), Gaps = 25/417 (5%) Query: 202 IIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPV 261 I F + E++ N++ + Y PTP+Q IP+ RD++A A TGSGKTAAFLLP+ Sbjct: 179 IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPI 238 Query: 262 I-----------MRALFES-------KTPSALILTPTRELAIQIERQAKELMSGLPRMKT 303 + +RA+ E+ + P +L+L PTRELA+QI +A++ S R++ Sbjct: 239 LSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKF-SYRSRVRP 297 Query: 304 VLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGF 363 ++ GG + Q+ L++ +++ATPGRL+D++++ + L K +V+DEAD ML MGF Sbjct: 298 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 357 Query: 364 QQQVLDILENI---PNDCQ-TILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQ 419 + Q+ I+E P + T++ SAT P I+ LA L + + G N+ Q Sbjct: 358 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 417 Query: 420 IILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEK 479 ++WVE+ K+ L ++LN LVFV+ K GAD L + + G SIH ++ Sbjct: 418 KVVWVEESDKRSFLLDLLNATGK-DSLTLVFVETKKGADSLEDFLYH-EGYACTSIHGDR 475 Query: 480 SQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRL 539 SQ +R+ L G ++V+T V RGLD+ +V+ V+NFD+PS ++EYVH+IGR GR+ Sbjct: 476 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRV 535 Query: 540 GQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQ 596 G G A +F N + + D+ + +P L N Y H K + + K ++ Sbjct: 536 GNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSR 592 >gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Homo sapiens] Length = 660 Score = 230 bits (587), Expect = 3e-60 Identities = 145/417 (34%), Positives = 229/417 (54%), Gaps = 25/417 (5%) Query: 202 IIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPV 261 I +F + E++ N++ + Y PTP+Q IP+ RD++A A TGSGKTAAFLLP+ Sbjct: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPI 236 Query: 262 I-----------MRALFES-------KTPSALILTPTRELAIQIERQAKELMSGLPRMKT 303 + ++A+ E+ + P +L+L PTRELA+QI +A++ S R++ Sbjct: 237 LSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKF-SYRSRVRP 295 Query: 304 VLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGF 363 ++ GG + Q+ L++ +++ATPGRL+D++++ + L K +V+DEAD ML MGF Sbjct: 296 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 355 Query: 364 QQQVLDILENI---PNDCQ-TILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQ 419 + Q+ I+E P + T++ SAT P I+ LA L + + G N+ Q Sbjct: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415 Query: 420 IILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEK 479 ++WVED K+ L +IL LVFV+ K GAD L + + G SIH ++ Sbjct: 416 KVVWVEDLDKRSFLLDILGATGS-DSLTLVFVETKKGADSLEDFLYH-EGYACTSIHGDR 473 Query: 480 SQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRL 539 SQ +R+ L G ++V+T V RGLD+ +VR V+NFD+PS ++EYVH+IGR GR+ Sbjct: 474 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRV 533 Query: 540 GQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQ 596 G G A +F N + + D+ + +P L N Y H K + + K + Sbjct: 534 GNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNR 590 >gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Homo sapiens] Length = 660 Score = 230 bits (587), Expect = 3e-60 Identities = 145/417 (34%), Positives = 229/417 (54%), Gaps = 25/417 (5%) Query: 202 IIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPV 261 I +F + E++ N++ + Y PTP+Q IP+ RD++A A TGSGKTAAFLLP+ Sbjct: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPI 236 Query: 262 I-----------MRALFES-------KTPSALILTPTRELAIQIERQAKELMSGLPRMKT 303 + ++A+ E+ + P +L+L PTRELA+QI +A++ S R++ Sbjct: 237 LSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKF-SYRSRVRP 295 Query: 304 VLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGF 363 ++ GG + Q+ L++ +++ATPGRL+D++++ + L K +V+DEAD ML MGF Sbjct: 296 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 355 Query: 364 QQQVLDILENI---PNDCQ-TILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQ 419 + Q+ I+E P + T++ SAT P I+ LA L + + G N+ Q Sbjct: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415 Query: 420 IILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEK 479 ++WVED K+ L +IL LVFV+ K GAD L + + G SIH ++ Sbjct: 416 KVVWVEDLDKRSFLLDILGATGS-DSLTLVFVETKKGADSLEDFLYH-EGYACTSIHGDR 473 Query: 480 SQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRL 539 SQ +R+ L G ++V+T V RGLD+ +VR V+NFD+PS ++EYVH+IGR GR+ Sbjct: 474 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRV 533 Query: 540 GQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQ 596 G G A +F N + + D+ + +P L N Y H K + + K + Sbjct: 534 GNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNR 590 >gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sapiens] Length = 648 Score = 220 bits (561), Expect = 3e-57 Identities = 141/398 (35%), Positives = 225/398 (56%), Gaps = 19/398 (4%) Query: 211 PEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESK 270 PEV+ N+KK+G++ PTPIQ Q P+ L G D++ A TG+GKT +L+P + + + Sbjct: 251 PEVME-NIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPS 309 Query: 271 T------PSALILTPTRELAIQIERQA-KELMSGLPRMKTVLLVGGLPLPPQLYRLQQHV 323 P L+LTPTRELA+Q+E + K GL ++V + GG Q+ L++ V Sbjct: 310 LKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGL---RSVCVYGGGNRDEQIEELKKGV 366 Query: 324 KVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILV 383 +IIATPGRL D+ + V L + +V+DEAD ML MGF+ Q++ IL ++ D QT++ Sbjct: 367 DIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMT 426 Query: 384 SATIPTSIEQLASQLLHNPVRIITGEKNL-PCANVRQIILWVEDPAKKKKLFEILNDKKL 442 SAT P S+ +LA L P+ + G +L ++V+Q I+ + K + L Sbjct: 427 SATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMS- 485 Query: 443 FKPPVLVFVDCKLGADLLSEAVQKITGLKSI-SIHSEKSQIERKNILKGLLEGDYEVVVS 501 V+VFV K AD LS + I G S+ S+H ++ Q +R+ L+ G ++++ Sbjct: 486 STDKVIVFVSRKAVADHLSSDL--ILGNISVESLHGDREQRDREKALENFKTGKVRILIA 543 Query: 502 TGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIA 561 T + RGLD+ V V NFD P +++EYVH+IGR GR G+ G +IT + N R+ ++ Sbjct: 544 TDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELI 603 Query: 562 KRVKPTGSILPPQLLNSP---YLHDQKRKEQQKDKQTQ 596 ++ +P +L++ H QKR+ ++K ++ Q Sbjct: 604 NILERANQSIPEELVSMAERFKAHQQKREMERKMERPQ 641 >gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapiens] Length = 491 Score = 217 bits (553), Expect = 2e-56 Identities = 157/473 (33%), Positives = 245/473 (51%), Gaps = 40/473 (8%) Query: 176 NLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN----HNLKKSGYEVPTPIQM 231 NL++++I L+ + I VQG ++ PI F+ +N N+ +G+++PTPIQM Sbjct: 26 NLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQM 85 Query: 232 QMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFES-KTPSALILTPTRELAIQIERQ 290 Q IPV L GR++LASA TGSGKT AF +P++M+ + K ALI++PTRELA QI R+ Sbjct: 86 QAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRE 145 Query: 291 AKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQS--SVELCGVK 348 ++ G ++ + + + +++ TP RL+ ++KQ ++L V+ Sbjct: 146 LIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVE 205 Query: 349 IVVVDEADTML---KMGFQQQVLDI-LENIPNDCQTILVSATIPTSIEQLASQLLHNPVR 404 +VVDE+D + K GF+ Q+ I L + + + SAT +EQ L N + Sbjct: 206 WLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVIS 265 Query: 405 IITGEKNLPCANVRQIILWV-EDPAKKKKLFEILNDKKLFKPPVLVFVDC-KLGADLLSE 462 + G +N V Q +L+V + K + E++ KK F PPVLVFV + +L E Sbjct: 266 VSIGARNSAVETVEQELLFVGSETGKLLAMRELV--KKGFNPPVLVFVQSIERAKELFHE 323 Query: 463 AVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDM 522 + + G+ IH+E++Q +R N + G V++ T +L RG+D V LV+N+D Sbjct: 324 LIYE--GINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDF 381 Query: 523 PSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLN-SPYL 581 P+S EY+H+IGR GR G G AITF + K L +A ++ G +P + L Sbjct: 382 PTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLL 441 Query: 582 HDQKRK-------------------EQQKDKQTQNDLVTGANLMDIIRKHDKS 615 QK+K E+ KDKQ + VTG N + DKS Sbjct: 442 SKQKKKMIKKPLERESISTTPKCFLEKAKDKQKK---VTGQNSKKKVALEDKS 491 >gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapiens] Length = 599 Score = 217 bits (553), Expect = 2e-56 Identities = 157/473 (33%), Positives = 245/473 (51%), Gaps = 40/473 (8%) Query: 176 NLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN----HNLKKSGYEVPTPIQM 231 NL++++I L+ + I VQG ++ PI F+ +N N+ +G+++PTPIQM Sbjct: 134 NLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQM 193 Query: 232 QMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFES-KTPSALILTPTRELAIQIERQ 290 Q IPV L GR++LASA TGSGKT AF +P++M+ + K ALI++PTRELA QI R+ Sbjct: 194 QAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRE 253 Query: 291 AKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQS--SVELCGVK 348 ++ G ++ + + + +++ TP RL+ ++KQ ++L V+ Sbjct: 254 LIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVE 313 Query: 349 IVVVDEADTML---KMGFQQQVLDI-LENIPNDCQTILVSATIPTSIEQLASQLLHNPVR 404 +VVDE+D + K GF+ Q+ I L + + + SAT +EQ L N + Sbjct: 314 WLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVIS 373 Query: 405 IITGEKNLPCANVRQIILWV-EDPAKKKKLFEILNDKKLFKPPVLVFVDC-KLGADLLSE 462 + G +N V Q +L+V + K + E++ KK F PPVLVFV + +L E Sbjct: 374 VSIGARNSAVETVEQELLFVGSETGKLLAMRELV--KKGFNPPVLVFVQSIERAKELFHE 431 Query: 463 AVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDM 522 + + G+ IH+E++Q +R N + G V++ T +L RG+D V LV+N+D Sbjct: 432 LIYE--GINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDF 489 Query: 523 PSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLN-SPYL 581 P+S EY+H+IGR GR G G AITF + K L +A ++ G +P + L Sbjct: 490 PTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLL 549 Query: 582 HDQKRK-------------------EQQKDKQTQNDLVTGANLMDIIRKHDKS 615 QK+K E+ KDKQ + VTG N + DKS Sbjct: 550 SKQKKKMIKKPLERESISTTPKCFLEKAKDKQKK---VTGQNSKKKVALEDKS 599 >gi|7661920 eukaryotic translation initiation factor 4A, isoform 3 [Homo sapiens] Length = 411 Score = 208 bits (530), Expect = 1e-53 Identities = 119/358 (33%), Positives = 205/358 (57%), Gaps = 7/358 (1%) Query: 205 FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMR 264 F+ L E L + G+E P+ IQ + I + GRD++A + +G+GKTA F + V+ Sbjct: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 Query: 265 ALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVK 324 + + ALIL PTRELA+QI++ L + ++ +GG + + +L Sbjct: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYGQH 158 Query: 325 VIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVS 384 V+ TPGR+ D+I++ S+ +K++V+DEAD ML GF++Q+ D+ +P Q +L+S Sbjct: 159 VVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLIS 218 Query: 385 ATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILND--KKL 442 AT+P I ++ ++ + +P+RI+ L ++Q + VE +++ F+ L D L Sbjct: 219 ATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVE---REEWKFDTLCDLYDTL 275 Query: 443 FKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVST 502 ++F + K D L+E +++ S S+H + Q ER++I+K G V++ST Sbjct: 276 TITQAVIFCNTKRKVDWLTEKMREANFTVS-SMHGDMPQKERESIMKEFRSGASRVLIST 334 Query: 503 GVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDI 560 V RGLD+ V L++N+D+P++ + Y+H+IGR GR G+ G AI F+ N+ R+ DI Sbjct: 335 DVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392 >gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapiens] Length = 631 Score = 204 bits (520), Expect = 1e-52 Identities = 124/393 (31%), Positives = 213/393 (54%), Gaps = 13/393 (3%) Query: 211 PEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMR------ 264 P++L ++ + G PTPIQ Q P+ L G D++ A TG+GKT ++L+P + Sbjct: 231 PDLLK-SIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPI 289 Query: 265 ALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVK 324 + + P L+LTPTRELA+ +E + + +K++ + GG Q+ + + V Sbjct: 290 SREQRNGPGMLVLTPTRELALHVEAECSKY--SYKGLKSICIYGGRNRNGQIEDISKGVD 347 Query: 325 VIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVS 384 +IIATPGRL D+ +SV L + +V+DEAD ML M F+ Q+ IL ++ D QT++ S Sbjct: 348 IIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTS 407 Query: 385 ATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFK 444 AT P ++ QLA L +P+ + G NL N + + V +K+ L + + Sbjct: 408 ATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPN 467 Query: 445 PPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGV 504 V++FV K AD LS I G+ + S+H Q +++ ++ G+ +++++T + Sbjct: 468 DKVIMFVSQKHIADDLSSDF-NIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526 Query: 505 LGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRV 564 + RGLDL V V N+D P ++D YVH++G +GR G+ GT++T I ++ ++ K + Sbjct: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586 Query: 565 KPTGSILPPQLL---NSPYLHDQKRKEQQKDKQ 594 +P L+ L+ QKR + + ++ Sbjct: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRK 619 >gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 [Homo sapiens] Length = 455 Score = 204 bits (519), Expect = 2e-52 Identities = 127/368 (34%), Positives = 203/368 (55%), Gaps = 11/368 (2%) Query: 197 EVTRPIID------FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTG 250 E ++PI++ F+ + +VL + G+ PT IQ++ IP+ L GRDI+ A+TG Sbjct: 12 EASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETG 71 Query: 251 SGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGL 310 SGKT AF LP++ L + AL+LTPTRELA QI Q + L S + +++ ++VGG+ Sbjct: 72 SGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGI 130 Query: 311 PLPPQLYRLQQHVKVIIATPGRLLDIIKQS-SVELCGVKIVVVDEADTMLKMGFQQQVLD 369 Q L + +IIATPGRL+D ++ + L +K +V+DEAD +L M F+ +V Sbjct: 131 DSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDK 190 Query: 370 ILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAK 429 IL+ IP D +T L SAT+ +++L L NPV+ K ++Q +++ K Sbjct: 191 ILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFK 250 Query: 430 KKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILK 489 L ILN+ L ++F + ++ + G +I +H + SQ +R L Sbjct: 251 DTYLVYILNE--LAGNSFMIFCSTCNNTQRTALLLRNL-GFTAIPLHGQMSQSKRLGSLN 307 Query: 490 GLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFI 549 ++++T V RGLD+ V +VVNFD+P+ +Y+H++GR R G++G AITF+ Sbjct: 308 KFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFV 367 Query: 550 NNNSKRLF 557 LF Sbjct: 368 TQYDVELF 375 >gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sapiens] Length = 796 Score = 204 bits (518), Expect = 3e-52 Identities = 137/455 (30%), Positives = 231/455 (50%), Gaps = 15/455 (3%) Query: 132 KAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLK----- 186 K K + E +E+ L + SE E+ Y + + ++++ K Sbjct: 142 KEKEAKEGSEPKEQEDLQENDEEGSEDEAS-ETDYSSADENILTKADTLKVKDRKKKKKK 200 Query: 187 -QQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILA 245 Q+ G + + F+ +L L + G++ PTPIQ IPVGLLG+DI A Sbjct: 201 GQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICA 260 Query: 246 SADTGSGKTAAFLLPVIMRALFESK---TPSALILTPTRELAIQIERQAKELMSGLPRMK 302 A TG+GKTAAF LPV+ R +++ + L+L PTREL IQ+ ++L + Sbjct: 261 CAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQ-FCNIT 319 Query: 303 TVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQS-SVELCGVKIVVVDEADTMLKM 361 T L VGGL + Q L+ ++IATPGRL+D + S L ++++++DEAD ML Sbjct: 320 TCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDE 379 Query: 362 GFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQII 421 F++Q+ +I+ + QT+L SAT+ ++ LAS L NPVRI +RQ Sbjct: 380 YFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEF 439 Query: 422 LWVEDPAK-KKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKS 480 + + + ++ + F V++F K A + + + GL+ +H S Sbjct: 440 IRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRM-HILLGLMGLQVGELHGNLS 498 Query: 481 QIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLG 540 Q +R L+ + +++V+T V RGLD+ V+ V+NF MP+++ YVH++GR R G Sbjct: 499 QTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAG 558 Query: 541 QNGTAITFINNNSKRLFWDIAKRVK-PTGSILPPQ 574 + G +++ + + +++ +I K K P + + PQ Sbjct: 559 RAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQ 593 >gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapiens] Length = 483 Score = 196 bits (499), Expect = 4e-50 Identities = 121/381 (31%), Positives = 201/381 (52%), Gaps = 8/381 (2%) Query: 204 DFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIM 263 +FE L L + + G+E P+PIQ + IP+ L GRDILA A G+GK+ A+L+P++ Sbjct: 97 EFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLE 156 Query: 264 RALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHV 323 R + A+++ PTRELA+Q+ + ++ + K + GG L + RL V Sbjct: 157 RLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTV 216 Query: 324 KVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILV 383 V+IATPGR+LD+IK+ ++ V+++V+DEAD +L F Q + DI+ +P + Q +L Sbjct: 217 HVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLY 276 Query: 384 SATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLF 443 SAT P S+++ + L P I E+ L V Q +V + K L + + ++ Sbjct: 277 SATFPLSVQKFMNSHLQKPYEINLMEE-LTLKGVTQYYAYVTERQKVHCLNTLFSRLQIN 335 Query: 444 KPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTG 503 + ++F + +LL++ + ++ G IH++ Q R + G +V T Sbjct: 336 QS--IIFCNSSQRVELLAKKISQL-GYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD 392 Query: 504 VLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINN----NSKRLFWD 559 + RG+D+ +V +V+NFD P + Y+H+IGR GR G G AI I N K + Sbjct: 393 LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQ 452 Query: 560 IAKRVKPTGSILPPQLLNSPY 580 + +KP S + L + Y Sbjct: 453 LGTEIKPIPSNIDKSLYVAEY 473 >gi|83700235 eukaryotic translation initiation factor 4A2 [Homo sapiens] Length = 407 Score = 196 bits (499), Expect = 4e-50 Identities = 113/372 (30%), Positives = 205/372 (55%), Gaps = 8/372 (2%) Query: 204 DFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIM 263 +F+ +L E L + G+E P+ IQ + I + G D++A A +G+GKTA F + ++ Sbjct: 34 NFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQ 93 Query: 264 RALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHV 323 + E K AL+L PTRELA QI++ L + +GG + ++ +LQ Sbjct: 94 QLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHAC-IGGTNVRNEMQKLQAEA 152 Query: 324 K-VIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTIL 382 +++ TPGR+ D++ + + +K+ V+DEAD ML GF+ Q+ +I + + Q +L Sbjct: 153 PHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVL 212 Query: 383 VSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILND--K 440 +SAT+PT + ++ + + +P+RI+ ++ L ++Q + VE +++ + L D + Sbjct: 213 LSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVE---REEWKLDTLCDLYE 269 Query: 441 KLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVV 500 L ++F++ + D L+E + S ++H + Q ER I++ G V++ Sbjct: 270 TLTITQAVIFLNTRRKVDWLTEKMHARDFTVS-ALHGDMDQKERDVIMREFRSGSSRVLI 328 Query: 501 STGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDI 560 +T +L RG+D+ V LV+N+D+P++ + Y+H+IGR GR G+ G AI F+ KR+ DI Sbjct: 329 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDI 388 Query: 561 AKRVKPTGSILP 572 T +P Sbjct: 389 ETFYNTTVEEMP 400 >gi|4503529 eukaryotic translation initiation factor 4A isoform 1 [Homo sapiens] Length = 406 Score = 196 bits (497), Expect = 7e-50 Identities = 113/363 (31%), Positives = 204/363 (56%), Gaps = 9/363 (2%) Query: 202 IID-FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLP 260 I+D F+ +L E L + G+E P+ IQ + I + G D++A A +G+GKTA F + Sbjct: 30 IVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAIS 89 Query: 261 VIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQ 320 ++ + + K AL+L PTRELA QI++ L + +GG + ++ +LQ Sbjct: 90 ILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGA-SCHACIGGTNVRAEVQKLQ 148 Query: 321 QHVK-VIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQ 379 +I+ TPGR+ D++ + + +K+ V+DEAD ML GF+ Q+ DI + + ++ Q Sbjct: 149 MEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQ 208 Query: 380 TILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILND 439 +L+SAT+P+ + ++ + + +P+RI+ ++ L +RQ + VE +++ + L D Sbjct: 209 VVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVE---REEWKLDTLCD 265 Query: 440 --KKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYE 497 + L ++F++ + D L+E + S ++H + Q ER I++ G Sbjct: 266 LYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS-AMHGDMDQKERDVIMREFRSGSSR 324 Query: 498 VVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLF 557 V+++T +L RG+D+ V LV+N+D+P++ + Y+H+IGR GR G+ G AI + KR Sbjct: 325 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTL 384 Query: 558 WDI 560 DI Sbjct: 385 RDI 387 >gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 [Homo sapiens] Length = 881 Score = 188 bits (477), Expect = 1e-47 Identities = 122/347 (35%), Positives = 187/347 (53%), Gaps = 4/347 (1%) Query: 205 FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMR 264 F+ L + + K GY+VPTPIQ + IPV L G+D++A A TGSGKTA FLLP+ R Sbjct: 98 FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157 Query: 265 ALFESKTPSA--LILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQH 322 S A LIL+PTRELA+Q + KEL +KT L++GG + Q L ++ Sbjct: 158 LKTHSAQTGARALILSPTRELALQTLKFTKEL-GKFTGLKTALILGGDRMEDQFAALHEN 216 Query: 323 VKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTIL 382 +IIATPGRL+ + + S++L V+ VV DEAD + +MGF +Q+ +I+ +P QT+L Sbjct: 217 PDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVL 276 Query: 383 VSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKL 442 SAT+P + + A L PV I ++ V + K L +L++ Sbjct: 277 FSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVVR 336 Query: 443 FKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVST 502 + +VFV K A+ L+E + + I+S RK L G ++ T Sbjct: 337 PQDQTVVFVATKHHAEYLTELL-TTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVT 395 Query: 503 GVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFI 549 + RGLD+ + V+N+ P+ ++H++GRV R G++GTA + + Sbjct: 396 DLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLV 442 >gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1 [Homo sapiens] Length = 882 Score = 188 bits (477), Expect = 1e-47 Identities = 122/347 (35%), Positives = 187/347 (53%), Gaps = 4/347 (1%) Query: 205 FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMR 264 F+ L + + K GY+VPTPIQ + IPV L G+D++A A TGSGKTA FLLP+ R Sbjct: 98 FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157 Query: 265 ALFESKTPSA--LILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQH 322 S A LIL+PTRELA+Q + KEL +KT L++GG + Q L ++ Sbjct: 158 LKTHSAQTGARALILSPTRELALQTLKFTKEL-GKFTGLKTALILGGDRMEDQFAALHEN 216 Query: 323 VKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTIL 382 +IIATPGRL+ + + S++L V+ VV DEAD + +MGF +Q+ +I+ +P QT+L Sbjct: 217 PDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVL 276 Query: 383 VSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKL 442 SAT+P + + A L PV I ++ V + K L +L++ Sbjct: 277 FSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVVR 336 Query: 443 FKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVST 502 + +VFV K A+ L+E + + I+S RK L G ++ T Sbjct: 337 PQDQTVVFVATKHHAEYLTELL-TTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVT 395 Query: 503 GVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFI 549 + RGLD+ + V+N+ P+ ++H++GRV R G++GTA + + Sbjct: 396 DLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLV 442 >gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapiens] Length = 427 Score = 181 bits (459), Expect = 2e-45 Identities = 114/383 (29%), Positives = 206/383 (53%), Gaps = 16/383 (4%) Query: 211 PEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESK 270 PE+L + G+E P+ +Q + IP +LG D+L A +G GKTA F+L + + + Sbjct: 53 PELLRA-IVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNG 111 Query: 271 TPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVK-VIIAT 329 + L++ TRELA QI ++ + +P +K + GGL + L+++ V++ T Sbjct: 112 QVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCPHVVVGT 171 Query: 330 PGRLLDIIKQSSVELCGVKIVVVDEADTMLK-MGFQQQVLDILENIPNDCQTILVSATIP 388 PGR+L +++ S L VK V+DE D ML+ + ++ V +I P++ Q ++ SAT+ Sbjct: 172 PGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLS 231 Query: 389 TSIEQLASQLLHNPVRI-ITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFKPPV 447 I + + + +P+ + + E L ++Q + ++D K +KLF++L+ + + V Sbjct: 232 KDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQ--V 289 Query: 448 LVFVD----CKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTG 503 ++FV C A LL E +I+IH +Q ER + + + ++V+T Sbjct: 290 IIFVKSVQRCMALAQLLVEQ-----NFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATN 344 Query: 504 VLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINN-NSKRLFWDIAK 562 + GRG+D+ V +V N+DMP D Y+H++ R GR G G AITF+++ N ++ D+ Sbjct: 345 LFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 404 Query: 563 RVKPTGSILPPQLLNSPYLHDQK 585 R + + LP ++ S Y+ + Sbjct: 405 RFEVNVAELPEEIDISTYIEQSR 427 >gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 [Homo sapiens] Length = 406 Score = 181 bits (458), Expect = 2e-45 Identities = 119/368 (32%), Positives = 188/368 (51%), Gaps = 60/368 (16%) Query: 197 EVTRPIID------FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTG 250 E ++PI++ F+ + +VL + G+ PT IQ++ IP+ L GRDI+ A+TG Sbjct: 12 EASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETG 71 Query: 251 SGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGL 310 SGKT AF LP++ L + AL+LTPTRELA QI Q + L S + +++ ++VGG+ Sbjct: 72 SGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGI 130 Query: 311 PLPPQLYRLQQHVKVIIATPGRLLDIIKQS-SVELCGVKIVVVDEADTMLKMGFQQQVLD 369 Q L + +IIATPGRL+D ++ + L +K +V+DEAD +L M F+ +V Sbjct: 131 DSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDK 190 Query: 370 ILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAK 429 IL+ IP D +T L SAT+ +++L L NPV+ K ++Q +++ K Sbjct: 191 ILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFK 250 Query: 430 KKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILK 489 K+L + K + + ++IL Sbjct: 251 SKRLGSL-----------------------------------------NKFKAKARSIL- 268 Query: 490 GLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFI 549 ++T V RGLD+ V +VVNFD+P+ +Y+H++GR R G++G AITF+ Sbjct: 269 ----------LATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFV 318 Query: 550 NNNSKRLF 557 LF Sbjct: 319 TQYDVELF 326 >gi|4758112 HLA-B associated transcript 1 [Homo sapiens] Length = 428 Score = 179 bits (455), Expect = 5e-45 Identities = 120/426 (28%), Positives = 218/426 (51%), Gaps = 21/426 (4%) Query: 174 ILNLQEDQIENLKQQLGIL------VQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPT 227 +L+ ++D++E G V+G V+ F L L + G+E P+ Sbjct: 10 LLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPS 69 Query: 228 PIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQI 287 +Q + IP +LG D+L A +G GKTA F+L + + + S L++ TRELA QI Sbjct: 70 EVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQI 129 Query: 288 ERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHV-KVIIATPGRLLDIIKQSSVELCG 346 ++ + +P +K + GGL + L+++ +++ TPGR+L + + S+ L Sbjct: 130 SKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKH 189 Query: 347 VKIVVVDEADTML-KMGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRI 405 +K ++DE D ML ++ ++ V +I P++ Q ++ SAT+ I + + + +P+ I Sbjct: 190 IKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEI 249 Query: 406 -ITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFKPPVLVFVD----CKLGADLL 460 + E L ++Q + ++D K +KLF++L+ + + V++FV C A LL Sbjct: 250 FVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQ--VVIFVKSVQRCIALAQLL 307 Query: 461 SEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNF 520 E +I+IH Q ER + + + ++V+T + GRG+D+ V + N+ Sbjct: 308 VE-----QNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNY 362 Query: 521 DMPSSMDEYVHQIGRVGRLGQNGTAITFINN-NSKRLFWDIAKRVKPTGSILPPQLLNSP 579 DMP D Y+H++ R GR G G AITF+++ N ++ D+ R + S LP ++ S Sbjct: 363 DMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDISS 422 Query: 580 YLHDQK 585 Y+ + Sbjct: 423 YIEQTR 428 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.135 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,417,712 Number of Sequences: 37866 Number of extensions: 1160503 Number of successful extensions: 3959 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 74 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 3680 Number of HSP's gapped (non-prelim): 128 length of query: 619 length of database: 18,247,518 effective HSP length: 108 effective length of query: 511 effective length of database: 14,157,990 effective search space: 7234732890 effective search space used: 7234732890 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.