Guide to the Human Genome
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Search of human proteins with 188035877

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
         (619 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...  1225   0.0  
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   268   1e-71
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   266   3e-71
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  249   4e-66
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         242   8e-64
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          242   8e-64
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    239   4e-63
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            239   5e-63
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            239   5e-63
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   238   2e-62
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   238   2e-62
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...   238   2e-62
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   232   9e-61
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   230   3e-60
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   230   3e-60
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   220   3e-57
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi...   217   2e-56
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi...   217   2e-56
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   208   1e-53
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...   204   1e-52
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   204   2e-52
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   204   3e-52
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   196   4e-50
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   196   4e-50
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   196   7e-50
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   188   1e-47
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   188   1e-47
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi...   181   2e-45
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ...   181   2e-45
gi|4758112 HLA-B associated transcript 1 [Homo sapiens]               179   5e-45

>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score = 1225 bits (3169), Expect = 0.0
 Identities = 619/619 (100%), Positives = 619/619 (100%)

Query: 1   MFVPRSLKIKRNANDDGKSCVAKIIKPDPEDLQLDKSRDVPVDAVATEAATIDRHISESC 60
           MFVPRSLKIKRNANDDGKSCVAKIIKPDPEDLQLDKSRDVPVDAVATEAATIDRHISESC
Sbjct: 1   MFVPRSLKIKRNANDDGKSCVAKIIKPDPEDLQLDKSRDVPVDAVATEAATIDRHISESC 60

Query: 61  PFPSPGGQLAEVHSVSPEQGAKDSHPSEEPVKSFSKTQRWAEPGEPICVVCGRYGEYICD 120
           PFPSPGGQLAEVHSVSPEQGAKDSHPSEEPVKSFSKTQRWAEPGEPICVVCGRYGEYICD
Sbjct: 61  PFPSPGGQLAEVHSVSPEQGAKDSHPSEEPVKSFSKTQRWAEPGEPICVVCGRYGEYICD 120

Query: 121 KTDEDVCSLECKAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQED 180
           KTDEDVCSLECKAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQED
Sbjct: 121 KTDEDVCSLECKAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQED 180

Query: 181 QIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLG 240
           QIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLG
Sbjct: 181 QIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLG 240

Query: 241 RDILASADTGSGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPR 300
           RDILASADTGSGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPR
Sbjct: 241 RDILASADTGSGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPR 300

Query: 301 MKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLK 360
           MKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLK
Sbjct: 301 MKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLK 360

Query: 361 MGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQI 420
           MGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQI
Sbjct: 361 MGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQI 420

Query: 421 ILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKS 480
           ILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKS
Sbjct: 421 ILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKS 480

Query: 481 QIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLG 540
           QIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLG
Sbjct: 481 QIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLG 540

Query: 541 QNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLV 600
           QNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLV
Sbjct: 541 QNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLV 600

Query: 601 TGANLMDIIRKHDKSNSQK 619
           TGANLMDIIRKHDKSNSQK
Sbjct: 601 TGANLMDIIRKHDKSNSQK 619


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  268 bits (684), Expect = 1e-71
 Identities = 156/441 (35%), Positives = 258/441 (58%), Gaps = 13/441 (2%)

Query: 144 EKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLKQQL-GILVQGQEVTRPI 202
           ++ KL  P         P   ++ Y E P +  + ++++   + ++ GI V+G+   +PI
Sbjct: 313 KQRKLLEPVDHGKIEYEPFRKNF-YVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPI 371

Query: 203 IDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVI 262
             +  C +   + ++LKK GYE PTPIQ Q IP  + GRD++  A TGSGKT AFLLP+ 
Sbjct: 372 KSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMF 431

Query: 263 -----MRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLY 317
                 R+L E + P A+I+TPTRELA+QI ++ K+    L  ++ V + GG  +  Q+ 
Sbjct: 432 RHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLG-LRVVCVYGGTGISEQIA 490

Query: 318 RLQQHVKVIIATPGRLLDIIKQSS---VELCGVKIVVVDEADTMLKMGFQQQVLDILENI 374
            L++  ++I+ TPGR++D++  +S     L  V  VV+DEAD M  MGF+ QV+ I++N+
Sbjct: 491 ELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNV 550

Query: 375 PNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLF 434
             D QT++ SAT P ++E LA ++L  P+ +  G +++ C++V Q ++ +E+  K  KL 
Sbjct: 551 RPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLL 610

Query: 435 EILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEG 494
           E+L   +     V++FVD +  AD L + + + +    +S+H    Q +R +I+     G
Sbjct: 611 ELLGHYQE-SGSVIIFVDKQEHADGLLKDLMRAS-YPCMSLHGGIDQYDRDSIINDFKNG 668

Query: 495 DYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSK 554
             +++V+T V  RGLD+  + LVVN+  P+  ++YVH+ GR GR G  G A TFI  +  
Sbjct: 669 TCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQA 728

Query: 555 RLFWDIAKRVKPTGSILPPQL 575
           R   DI K ++ +G+ +PP L
Sbjct: 729 RYAGDIIKALELSGTAVPPDL 749


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  266 bits (681), Expect = 3e-71
 Identities = 152/430 (35%), Positives = 248/430 (57%), Gaps = 40/430 (9%)

Query: 186 KQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILA 245
           ++   I  +G ++  PI  ++  SLP  +   + K GY+ PTPIQ Q IP+GL  RDI+ 
Sbjct: 374 REDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIG 433

Query: 246 SADTGSGKTAAFLLPVIM---------RALFESKTPSALILTPTRELAIQIERQAKELMS 296
            A+TGSGKTAAFL+P+++         R     + P A+IL PTRELA QIE +  +   
Sbjct: 434 VAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGK 493

Query: 297 GLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEAD 356
            L  ++TV ++GG+    Q +RL+   +++IATPGRL+D+++   + L     VV+DEAD
Sbjct: 494 PL-GIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEAD 552

Query: 357 TMLKMGFQQQVLDILENIP--------------------------NDCQTILVSATIPTS 390
            M+ MGF+  V  ILE++P                             QT++ +AT+P +
Sbjct: 553 RMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPA 612

Query: 391 IEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFKPPVLVF 450
           +E+LA   L  P  +  G    P   V Q +  + +  K+KKL  IL  ++ F PP+++F
Sbjct: 613 VERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAIL--EQGFDPPIIIF 670

Query: 451 VDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLD 510
           V+ K G D+L+++++K+ G  + ++H  K Q +R+  L  L  G  +++V+T V GRG+D
Sbjct: 671 VNQKKGCDVLAKSLEKM-GYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGID 729

Query: 511 LISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRV-KPTGS 569
           +  V +VVN+DM  ++++Y+H+IGR GR G++G AITF+      +F+++ + + +   S
Sbjct: 730 IQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVS 789

Query: 570 ILPPQLLNSP 579
             PP+L N P
Sbjct: 790 SCPPELANHP 799


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  249 bits (637), Expect = 4e-66
 Identities = 157/472 (33%), Positives = 245/472 (51%), Gaps = 37/472 (7%)

Query: 121 KTDEDVCSLECKAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQED 180
           K +E +     + + L+ VKE  +     +P K    P              ++L++ E+
Sbjct: 111 KEEEKILESVAEGRALMSVKEMAKGITYDDPIKTSWTPPR------------YVLSMSEE 158

Query: 181 QIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLG 240
           + E ++++  ILV+G  +  PI  F+    P  +   LKK G   PTPIQ+Q IP  L G
Sbjct: 159 RHERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSG 218

Query: 241 RDILASADTGSGKTAAFLLPVIMRALFESKT--------PSALILTPTRELAIQ----IE 288
           RD++  A TGSGKT  F LPVIM  L + K         P  LI+ P+RELA Q    +E
Sbjct: 219 RDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILE 278

Query: 289 RQAKELMS-GLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGV 347
              + L     P ++  L +GG+ +  Q+  ++  V +++ATPGRL+D++++  V L   
Sbjct: 279 YYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDIC 338

Query: 348 KIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIIT 407
           + + +DEAD M+ MGF+  +  I        QT+L SAT+P  I+  A   L  PV I  
Sbjct: 339 RYLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 398

Query: 408 GEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKI 467
           G       +V Q + +V++ AK   L E L       PPVL+F + K   D + E +  +
Sbjct: 399 GRAGAASLDVIQEVEYVKEEAKMVYLLECLQKT---PPPVLIFAEKKADVDAIHEYL-LL 454

Query: 468 TGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMD 527
            G+++++IH  K Q ER   ++   EG  +V+V+T V  +GLD  +++ V+N+DMP  ++
Sbjct: 455 KGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIE 514

Query: 528 EYVHQIGRVGRLGQNGTAITFINN--------NSKRLFWDIAKRVKPTGSIL 571
            YVH+IGR GR G  G A TFIN         + K L  +  ++V P   +L
Sbjct: 515 NYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVL 566


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  242 bits (617), Expect = 8e-64
 Identities = 146/426 (34%), Positives = 232/426 (54%), Gaps = 10/426 (2%)

Query: 159 ESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVT-RPIIDFEHCSLPEVLNHN 217
           E P      Y EHP +  L   +++ L+++  I V+G +V  +P+  F H + P+ +   
Sbjct: 126 ELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDV 185

Query: 218 LKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRA-----LFESKTP 272
           L    +  PTPIQ Q  P+ L GRD++  A TGSGKT A+LLP I+       L     P
Sbjct: 186 LMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGP 245

Query: 273 SALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGR 332
             L+L PTRELA Q+++ A +      R+K+  + GG P  PQ+  L++ V++ IATPGR
Sbjct: 246 ICLVLAPTRELAQQVQQVADDY-GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGR 304

Query: 333 LLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIE 392
           L+D ++     L     +V+DEAD ML MGF+ Q+  I++ I  D QT++ SAT P  + 
Sbjct: 305 LIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVR 364

Query: 393 QLASQLLHNPVRIITGEKNLPC-ANVRQIILWVEDPAKKKKLFEILNDKKLFKP-PVLVF 450
           QLA   L +  +I  G   L    N+ QI+    +  K  KL +++ +    K    ++F
Sbjct: 365 QLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIF 424

Query: 451 VDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLD 510
           V+ K   D L+  +++  G  ++ IH +KSQ ER  +L     G   ++++T V  RGLD
Sbjct: 425 VETKRRCDDLTRRMRR-DGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLD 483

Query: 511 LISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTGSI 570
           +  V+ V+N+D P+S ++YVH+IGR  R    GTA TF    + +   ++ K ++     
Sbjct: 484 VEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQA 543

Query: 571 LPPQLL 576
           + P+L+
Sbjct: 544 INPKLM 549


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  242 bits (617), Expect = 8e-64
 Identities = 146/426 (34%), Positives = 232/426 (54%), Gaps = 10/426 (2%)

Query: 159 ESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVT-RPIIDFEHCSLPEVLNHN 217
           E P      Y EHP +  L   +++ L+++  I V+G +V  +P+  F H + P+ +   
Sbjct: 126 ELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDV 185

Query: 218 LKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRA-----LFESKTP 272
           L    +  PTPIQ Q  P+ L GRD++  A TGSGKT A+LLP I+       L     P
Sbjct: 186 LMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGP 245

Query: 273 SALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGR 332
             L+L PTRELA Q+++ A +      R+K+  + GG P  PQ+  L++ V++ IATPGR
Sbjct: 246 ICLVLAPTRELAQQVQQVADDY-GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGR 304

Query: 333 LLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIE 392
           L+D ++     L     +V+DEAD ML MGF+ Q+  I++ I  D QT++ SAT P  + 
Sbjct: 305 LIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVR 364

Query: 393 QLASQLLHNPVRIITGEKNLPC-ANVRQIILWVEDPAKKKKLFEILNDKKLFKP-PVLVF 450
           QLA   L +  +I  G   L    N+ QI+    +  K  KL +++ +    K    ++F
Sbjct: 365 QLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIF 424

Query: 451 VDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLD 510
           V+ K   D L+  +++  G  ++ IH +KSQ ER  +L     G   ++++T V  RGLD
Sbjct: 425 VETKRRCDDLTRRMRR-DGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLD 483

Query: 511 LISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTGSI 570
           +  V+ V+N+D P+S ++YVH+IGR  R    GTA TF    + +   ++ K ++     
Sbjct: 484 VEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQA 543

Query: 571 LPPQLL 576
           + P+L+
Sbjct: 544 INPKLM 549


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  239 bits (611), Expect = 4e-63
 Identities = 146/428 (34%), Positives = 231/428 (53%), Gaps = 15/428 (3%)

Query: 159 ESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNL 218
           E P      Y+EHP +      ++E  ++   I V+G    +P+++F   + P  +   +
Sbjct: 50  ELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVI 109

Query: 219 KKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRA-----LFESKTPS 273
            +  +  PT IQ Q  PV L G D++  A TGSGKT ++LLP I+       L     P 
Sbjct: 110 ARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPI 169

Query: 274 ALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRL 333
            L+L PTRELA Q+++ A E      R+K+  + GG P  PQ+  L++ V++ IATPGRL
Sbjct: 170 CLVLAPTRELAQQVQQVAAEYCRAC-RLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 228

Query: 334 LDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIEQ 393
           +D ++     L     +V+DEAD ML MGF+ Q+  I++ I  D QT++ SAT P  + Q
Sbjct: 229 IDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQ 288

Query: 394 LASQLLHNPVRIITGEKNLPC-ANVRQIILWVEDPAKKKKLF----EILNDKKLFKPPVL 448
           LA   L + + I  G   L    N+ QI+    D  K +KL     EI+++K   +   +
Sbjct: 289 LAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEK---ENKTI 345

Query: 449 VFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRG 508
           VFV+ K   D L+  +++  G  ++ IH +KSQ ER  +L     G   ++++T V  RG
Sbjct: 346 VFVETKRRCDELTRKMRR-DGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRG 404

Query: 509 LDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTG 568
           LD+  V+ V+N+D P+S ++Y+H+IGR  R  + GTA TF   N+ +   D+   ++   
Sbjct: 405 LDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREAN 464

Query: 569 SILPPQLL 576
             + P+LL
Sbjct: 465 QAINPKLL 472


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  239 bits (610), Expect = 5e-63
 Identities = 152/460 (33%), Positives = 240/460 (52%), Gaps = 17/460 (3%)

Query: 156 SEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN 215
           SE + P      Y EH  I NL   Q+ +L+ +L + V G    RP   F H    E L 
Sbjct: 206 SEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLM 265

Query: 216 HNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESKT---- 271
           H ++KS Y  PTPIQ Q +PV L GRD++  A TGSGKTAAF+ P+++  + + +     
Sbjct: 266 HQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGD 325

Query: 272 -PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATP 330
            P A+I+ PTREL  QI  + K        +++V + GG  +  Q   LQ+  ++++ TP
Sbjct: 326 GPIAVIVCPTRELCQQIHAECKRFGKAY-NLRSVAVYGGGSMWEQAKALQEGAEIVVCTP 384

Query: 331 GRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTS 390
           GRL+D +K+ +  L  V  +V DEAD M  MGF+ QV  I  ++  D QT+L SAT    
Sbjct: 385 GRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKK 444

Query: 391 IEQLASQLLHNPVRIITGEKNLPCANVRQII-LWVEDPAK----KKKLFEILNDKKLFKP 445
           IE+LA  +L +P+R++ G+      +V QI+ +    P+K     ++L E  +       
Sbjct: 445 IEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGS---- 500

Query: 446 PVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVL 505
            VL+FV  K  A+ L+  + K  G     +H +  Q ER  ++    + D  V+V+T V 
Sbjct: 501 -VLLFVTKKANAEELANNL-KQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558

Query: 506 GRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVK 565
            RGLD+ S++ V+N+D+   +D + H+IGR GR G+ G A T +         D+ + ++
Sbjct: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLE 618

Query: 566 PTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLVTGANL 605
                +  +LL+    +   RK + K  + +   + G  L
Sbjct: 619 GANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGL 658


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  239 bits (610), Expect = 5e-63
 Identities = 152/460 (33%), Positives = 240/460 (52%), Gaps = 17/460 (3%)

Query: 156 SEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN 215
           SE + P      Y EH  I NL   Q+ +L+ +L + V G    RP   F H    E L 
Sbjct: 206 SEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLM 265

Query: 216 HNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESKT---- 271
           H ++KS Y  PTPIQ Q +PV L GRD++  A TGSGKTAAF+ P+++  + + +     
Sbjct: 266 HQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGD 325

Query: 272 -PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATP 330
            P A+I+ PTREL  QI  + K        +++V + GG  +  Q   LQ+  ++++ TP
Sbjct: 326 GPIAVIVCPTRELCQQIHAECKRFGKAY-NLRSVAVYGGGSMWEQAKALQEGAEIVVCTP 384

Query: 331 GRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTS 390
           GRL+D +K+ +  L  V  +V DEAD M  MGF+ QV  I  ++  D QT+L SAT    
Sbjct: 385 GRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKK 444

Query: 391 IEQLASQLLHNPVRIITGEKNLPCANVRQII-LWVEDPAK----KKKLFEILNDKKLFKP 445
           IE+LA  +L +P+R++ G+      +V QI+ +    P+K     ++L E  +       
Sbjct: 445 IEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGS---- 500

Query: 446 PVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVL 505
            VL+FV  K  A+ L+  + K  G     +H +  Q ER  ++    + D  V+V+T V 
Sbjct: 501 -VLLFVTKKANAEELANNL-KQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558

Query: 506 GRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVK 565
            RGLD+ S++ V+N+D+   +D + H+IGR GR G+ G A T +         D+ + ++
Sbjct: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLE 618

Query: 566 PTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLVTGANL 605
                +  +LL+    +   RK + K  + +   + G  L
Sbjct: 619 GANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGL 658


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  238 bits (606), Expect = 2e-62
 Identities = 150/427 (35%), Positives = 241/427 (56%), Gaps = 24/427 (5%)

Query: 141 EKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTR 200
           E  E S    P+     P  P +   ++  +   +N   D+ + +  +    V G +   
Sbjct: 232 EGGESSDTQGPKVTYIPPPPPEDEDSIFAHYQTGINF--DKYDTILVE----VSGHDAPP 285

Query: 201 PIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLP 260
            I+ FE  +L + LN+N+ K+GY   TP+Q   IP+ L GRD++A A TGSGKTAAFLLP
Sbjct: 286 AILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLP 345

Query: 261 VIMRALFESKT---------PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLP 311
           ++   + +  T         P  +I+ PTREL  QI  +A++   G   ++ V++ GG  
Sbjct: 346 ILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTC-VRAVVIYGGTQ 404

Query: 312 LPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDIL 371
           L   + ++ Q   ++ ATPGRL+DII +  + L  +K +V+DEAD ML MGF  ++  ++
Sbjct: 405 LGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 464

Query: 372 E--NIPN--DCQTILVSATIPTSIEQLASQLLH-NPVRIITGEKNLPCANVRQIILWVED 426
               +P+    QT++ SAT P  I++LA++ L  N + +  G+    C +V+Q +L V  
Sbjct: 465 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQ 524

Query: 427 PAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKN 486
            +K++KL EIL  + +     +VFV+ K  AD ++  + +   + + SIH ++ Q ER+ 
Sbjct: 525 FSKREKLVEIL--RNIGDERTMVFVETKKKADFIATFLCQ-EKISTTSIHGDREQREREQ 581

Query: 487 ILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAI 546
            L     G   V+V+T V  RGLD+ +V+ V+NFD+PS++DEYVH+IGR GR G  G AI
Sbjct: 582 ALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAI 641

Query: 547 TFINNNS 553
           +F +  S
Sbjct: 642 SFFDLES 648


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  238 bits (606), Expect = 2e-62
 Identities = 150/427 (35%), Positives = 241/427 (56%), Gaps = 24/427 (5%)

Query: 141 EKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTR 200
           E  E S    P+     P  P +   ++  +   +N   D+ + +  +    V G +   
Sbjct: 232 EGGESSDTQGPKVTYIPPPPPEDEDSIFAHYQTGINF--DKYDTILVE----VSGHDAPP 285

Query: 201 PIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLP 260
            I+ FE  +L + LN+N+ K+GY   TP+Q   IP+ L GRD++A A TGSGKTAAFLLP
Sbjct: 286 AILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLP 345

Query: 261 VIMRALFESKT---------PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLP 311
           ++   + +  T         P  +I+ PTREL  QI  +A++   G   ++ V++ GG  
Sbjct: 346 ILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTC-VRAVVIYGGTQ 404

Query: 312 LPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDIL 371
           L   + ++ Q   ++ ATPGRL+DII +  + L  +K +V+DEAD ML MGF  ++  ++
Sbjct: 405 LGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 464

Query: 372 E--NIPN--DCQTILVSATIPTSIEQLASQLLH-NPVRIITGEKNLPCANVRQIILWVED 426
               +P+    QT++ SAT P  I++LA++ L  N + +  G+    C +V+Q +L V  
Sbjct: 465 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQ 524

Query: 427 PAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKN 486
            +K++KL EIL  + +     +VFV+ K  AD ++  + +   + + SIH ++ Q ER+ 
Sbjct: 525 FSKREKLVEIL--RNIGDERTMVFVETKKKADFIATFLCQ-EKISTTSIHGDREQREREQ 581

Query: 487 ILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAI 546
            L     G   V+V+T V  RGLD+ +V+ V+NFD+PS++DEYVH+IGR GR G  G AI
Sbjct: 582 ALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAI 641

Query: 547 TFINNNS 553
           +F +  S
Sbjct: 642 SFFDLES 648


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score =  238 bits (606), Expect = 2e-62
 Identities = 150/427 (35%), Positives = 241/427 (56%), Gaps = 24/427 (5%)

Query: 141 EKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTR 200
           E  E S    P+     P  P +   ++  +   +N   D+ + +  +    V G +   
Sbjct: 198 EGGESSDTQGPKVTYIPPPPPEDEDSIFAHYQTGINF--DKYDTILVE----VSGHDAPP 251

Query: 201 PIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLP 260
            I+ FE  +L + LN+N+ K+GY   TP+Q   IP+ L GRD++A A TGSGKTAAFLLP
Sbjct: 252 AILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLP 311

Query: 261 VIMRALFESKT---------PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLP 311
           ++   + +  T         P  +I+ PTREL  QI  +A++   G   ++ V++ GG  
Sbjct: 312 ILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTC-VRAVVIYGGTQ 370

Query: 312 LPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDIL 371
           L   + ++ Q   ++ ATPGRL+DII +  + L  +K +V+DEAD ML MGF  ++  ++
Sbjct: 371 LGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 430

Query: 372 E--NIPN--DCQTILVSATIPTSIEQLASQLLH-NPVRIITGEKNLPCANVRQIILWVED 426
               +P+    QT++ SAT P  I++LA++ L  N + +  G+    C +V+Q +L V  
Sbjct: 431 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQ 490

Query: 427 PAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKN 486
            +K++KL EIL  + +     +VFV+ K  AD ++  + +   + + SIH ++ Q ER+ 
Sbjct: 491 FSKREKLVEIL--RNIGDERTMVFVETKKKADFIATFLCQ-EKISTTSIHGDREQREREQ 547

Query: 487 ILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAI 546
            L     G   V+V+T V  RGLD+ +V+ V+NFD+PS++DEYVH+IGR GR G  G AI
Sbjct: 548 ALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAI 607

Query: 547 TFINNNS 553
           +F +  S
Sbjct: 608 SFFDLES 614


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  232 bits (591), Expect = 9e-61
 Identities = 144/417 (34%), Positives = 230/417 (55%), Gaps = 25/417 (5%)

Query: 202 IIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPV 261
           I  F    + E++  N++ + Y  PTP+Q   IP+    RD++A A TGSGKTAAFLLP+
Sbjct: 179 IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPI 238

Query: 262 I-----------MRALFES-------KTPSALILTPTRELAIQIERQAKELMSGLPRMKT 303
           +           +RA+ E+       + P +L+L PTRELA+QI  +A++  S   R++ 
Sbjct: 239 LSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKF-SYRSRVRP 297

Query: 304 VLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGF 363
            ++ GG  +  Q+  L++   +++ATPGRL+D++++  + L   K +V+DEAD ML MGF
Sbjct: 298 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 357

Query: 364 QQQVLDILENI---PNDCQ-TILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQ 419
           + Q+  I+E     P   + T++ SAT P  I+ LA   L   + +  G       N+ Q
Sbjct: 358 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 417

Query: 420 IILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEK 479
            ++WVE+  K+  L ++LN         LVFV+ K GAD L + +    G    SIH ++
Sbjct: 418 KVVWVEESDKRSFLLDLLNATGK-DSLTLVFVETKKGADSLEDFLYH-EGYACTSIHGDR 475

Query: 480 SQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRL 539
           SQ +R+  L     G   ++V+T V  RGLD+ +V+ V+NFD+PS ++EYVH+IGR GR+
Sbjct: 476 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRV 535

Query: 540 GQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQ 596
           G  G A +F N  +  +  D+   +      +P  L N  Y H  K   + + K ++
Sbjct: 536 GNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSR 592


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  230 bits (587), Expect = 3e-60
 Identities = 145/417 (34%), Positives = 229/417 (54%), Gaps = 25/417 (5%)

Query: 202 IIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPV 261
           I +F    + E++  N++ + Y  PTP+Q   IP+    RD++A A TGSGKTAAFLLP+
Sbjct: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPI 236

Query: 262 I-----------MRALFES-------KTPSALILTPTRELAIQIERQAKELMSGLPRMKT 303
           +           ++A+ E+       + P +L+L PTRELA+QI  +A++  S   R++ 
Sbjct: 237 LSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKF-SYRSRVRP 295

Query: 304 VLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGF 363
            ++ GG  +  Q+  L++   +++ATPGRL+D++++  + L   K +V+DEAD ML MGF
Sbjct: 296 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 355

Query: 364 QQQVLDILENI---PNDCQ-TILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQ 419
           + Q+  I+E     P   + T++ SAT P  I+ LA   L   + +  G       N+ Q
Sbjct: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415

Query: 420 IILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEK 479
            ++WVED  K+  L +IL          LVFV+ K GAD L + +    G    SIH ++
Sbjct: 416 KVVWVEDLDKRSFLLDILGATGS-DSLTLVFVETKKGADSLEDFLYH-EGYACTSIHGDR 473

Query: 480 SQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRL 539
           SQ +R+  L     G   ++V+T V  RGLD+ +VR V+NFD+PS ++EYVH+IGR GR+
Sbjct: 474 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRV 533

Query: 540 GQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQ 596
           G  G A +F N  +  +  D+   +      +P  L N  Y H  K   + + K  +
Sbjct: 534 GNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNR 590


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  230 bits (587), Expect = 3e-60
 Identities = 145/417 (34%), Positives = 229/417 (54%), Gaps = 25/417 (5%)

Query: 202 IIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPV 261
           I +F    + E++  N++ + Y  PTP+Q   IP+    RD++A A TGSGKTAAFLLP+
Sbjct: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPI 236

Query: 262 I-----------MRALFES-------KTPSALILTPTRELAIQIERQAKELMSGLPRMKT 303
           +           ++A+ E+       + P +L+L PTRELA+QI  +A++  S   R++ 
Sbjct: 237 LSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKF-SYRSRVRP 295

Query: 304 VLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGF 363
            ++ GG  +  Q+  L++   +++ATPGRL+D++++  + L   K +V+DEAD ML MGF
Sbjct: 296 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 355

Query: 364 QQQVLDILENI---PNDCQ-TILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQ 419
           + Q+  I+E     P   + T++ SAT P  I+ LA   L   + +  G       N+ Q
Sbjct: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415

Query: 420 IILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEK 479
            ++WVED  K+  L +IL          LVFV+ K GAD L + +    G    SIH ++
Sbjct: 416 KVVWVEDLDKRSFLLDILGATGS-DSLTLVFVETKKGADSLEDFLYH-EGYACTSIHGDR 473

Query: 480 SQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRL 539
           SQ +R+  L     G   ++V+T V  RGLD+ +VR V+NFD+PS ++EYVH+IGR GR+
Sbjct: 474 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRV 533

Query: 540 GQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQ 596
           G  G A +F N  +  +  D+   +      +P  L N  Y H  K   + + K  +
Sbjct: 534 GNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNR 590


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  220 bits (561), Expect = 3e-57
 Identities = 141/398 (35%), Positives = 225/398 (56%), Gaps = 19/398 (4%)

Query: 211 PEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESK 270
           PEV+  N+KK+G++ PTPIQ Q  P+ L G D++  A TG+GKT  +L+P  +  + +  
Sbjct: 251 PEVME-NIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPS 309

Query: 271 T------PSALILTPTRELAIQIERQA-KELMSGLPRMKTVLLVGGLPLPPQLYRLQQHV 323
                  P  L+LTPTRELA+Q+E +  K    GL   ++V + GG     Q+  L++ V
Sbjct: 310 LKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGL---RSVCVYGGGNRDEQIEELKKGV 366

Query: 324 KVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILV 383
            +IIATPGRL D+   + V L  +  +V+DEAD ML MGF+ Q++ IL ++  D QT++ 
Sbjct: 367 DIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMT 426

Query: 384 SATIPTSIEQLASQLLHNPVRIITGEKNL-PCANVRQIILWVEDPAKKKKLFEILNDKKL 442
           SAT P S+ +LA   L  P+ +  G  +L   ++V+Q I+   +  K   +   L     
Sbjct: 427 SATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMS- 485

Query: 443 FKPPVLVFVDCKLGADLLSEAVQKITGLKSI-SIHSEKSQIERKNILKGLLEGDYEVVVS 501
               V+VFV  K  AD LS  +  I G  S+ S+H ++ Q +R+  L+    G   ++++
Sbjct: 486 STDKVIVFVSRKAVADHLSSDL--ILGNISVESLHGDREQRDREKALENFKTGKVRILIA 543

Query: 502 TGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIA 561
           T +  RGLD+  V  V NFD P +++EYVH+IGR GR G+ G +IT +  N  R+  ++ 
Sbjct: 544 TDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELI 603

Query: 562 KRVKPTGSILPPQLLNSP---YLHDQKRKEQQKDKQTQ 596
             ++     +P +L++       H QKR+ ++K ++ Q
Sbjct: 604 NILERANQSIPEELVSMAERFKAHQQKREMERKMERPQ 641


>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
           sapiens]
          Length = 491

 Score =  217 bits (553), Expect = 2e-56
 Identities = 157/473 (33%), Positives = 245/473 (51%), Gaps = 40/473 (8%)

Query: 176 NLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN----HNLKKSGYEVPTPIQM 231
           NL++++I  L+ +  I VQG ++  PI  F+       +N     N+  +G+++PTPIQM
Sbjct: 26  NLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQM 85

Query: 232 QMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFES-KTPSALILTPTRELAIQIERQ 290
           Q IPV L GR++LASA TGSGKT AF +P++M+    + K   ALI++PTRELA QI R+
Sbjct: 86  QAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRE 145

Query: 291 AKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQS--SVELCGVK 348
             ++  G      ++    +       +  +   +++ TP RL+ ++KQ    ++L  V+
Sbjct: 146 LIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVE 205

Query: 349 IVVVDEADTML---KMGFQQQVLDI-LENIPNDCQTILVSATIPTSIEQLASQLLHNPVR 404
            +VVDE+D +    K GF+ Q+  I L    +  +  + SAT    +EQ     L N + 
Sbjct: 206 WLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVIS 265

Query: 405 IITGEKNLPCANVRQIILWV-EDPAKKKKLFEILNDKKLFKPPVLVFVDC-KLGADLLSE 462
           +  G +N     V Q +L+V  +  K   + E++  KK F PPVLVFV   +   +L  E
Sbjct: 266 VSIGARNSAVETVEQELLFVGSETGKLLAMRELV--KKGFNPPVLVFVQSIERAKELFHE 323

Query: 463 AVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDM 522
            + +  G+    IH+E++Q +R N +     G   V++ T +L RG+D   V LV+N+D 
Sbjct: 324 LIYE--GINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDF 381

Query: 523 PSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLN-SPYL 581
           P+S  EY+H+IGR GR G  G AITF   + K L   +A  ++  G  +P  +      L
Sbjct: 382 PTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLL 441

Query: 582 HDQKRK-------------------EQQKDKQTQNDLVTGANLMDIIRKHDKS 615
             QK+K                   E+ KDKQ +   VTG N    +   DKS
Sbjct: 442 SKQKKKMIKKPLERESISTTPKCFLEKAKDKQKK---VTGQNSKKKVALEDKS 491


>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
           sapiens]
          Length = 599

 Score =  217 bits (553), Expect = 2e-56
 Identities = 157/473 (33%), Positives = 245/473 (51%), Gaps = 40/473 (8%)

Query: 176 NLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN----HNLKKSGYEVPTPIQM 231
           NL++++I  L+ +  I VQG ++  PI  F+       +N     N+  +G+++PTPIQM
Sbjct: 134 NLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQM 193

Query: 232 QMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFES-KTPSALILTPTRELAIQIERQ 290
           Q IPV L GR++LASA TGSGKT AF +P++M+    + K   ALI++PTRELA QI R+
Sbjct: 194 QAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRE 253

Query: 291 AKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQS--SVELCGVK 348
             ++  G      ++    +       +  +   +++ TP RL+ ++KQ    ++L  V+
Sbjct: 254 LIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVE 313

Query: 349 IVVVDEADTML---KMGFQQQVLDI-LENIPNDCQTILVSATIPTSIEQLASQLLHNPVR 404
            +VVDE+D +    K GF+ Q+  I L    +  +  + SAT    +EQ     L N + 
Sbjct: 314 WLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVIS 373

Query: 405 IITGEKNLPCANVRQIILWV-EDPAKKKKLFEILNDKKLFKPPVLVFVDC-KLGADLLSE 462
           +  G +N     V Q +L+V  +  K   + E++  KK F PPVLVFV   +   +L  E
Sbjct: 374 VSIGARNSAVETVEQELLFVGSETGKLLAMRELV--KKGFNPPVLVFVQSIERAKELFHE 431

Query: 463 AVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDM 522
            + +  G+    IH+E++Q +R N +     G   V++ T +L RG+D   V LV+N+D 
Sbjct: 432 LIYE--GINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDF 489

Query: 523 PSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLN-SPYL 581
           P+S  EY+H+IGR GR G  G AITF   + K L   +A  ++  G  +P  +      L
Sbjct: 490 PTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLL 549

Query: 582 HDQKRK-------------------EQQKDKQTQNDLVTGANLMDIIRKHDKS 615
             QK+K                   E+ KDKQ +   VTG N    +   DKS
Sbjct: 550 SKQKKKMIKKPLERESISTTPKCFLEKAKDKQKK---VTGQNSKKKVALEDKS 599


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  208 bits (530), Expect = 1e-53
 Identities = 119/358 (33%), Positives = 205/358 (57%), Gaps = 7/358 (1%)

Query: 205 FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMR 264
           F+   L E L   +   G+E P+ IQ + I   + GRD++A + +G+GKTA F + V+  
Sbjct: 40  FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99

Query: 265 ALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVK 324
              + +   ALIL PTRELA+QI++    L   +  ++    +GG  +   + +L     
Sbjct: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYGQH 158

Query: 325 VIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVS 384
           V+  TPGR+ D+I++ S+    +K++V+DEAD ML  GF++Q+ D+   +P   Q +L+S
Sbjct: 159 VVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLIS 218

Query: 385 ATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILND--KKL 442
           AT+P  I ++ ++ + +P+RI+     L    ++Q  + VE   +++  F+ L D    L
Sbjct: 219 ATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVE---REEWKFDTLCDLYDTL 275

Query: 443 FKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVST 502
                ++F + K   D L+E +++     S S+H +  Q ER++I+K    G   V++ST
Sbjct: 276 TITQAVIFCNTKRKVDWLTEKMREANFTVS-SMHGDMPQKERESIMKEFRSGASRVLIST 334

Query: 503 GVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDI 560
            V  RGLD+  V L++N+D+P++ + Y+H+IGR GR G+ G AI F+ N+  R+  DI
Sbjct: 335 DVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score =  204 bits (520), Expect = 1e-52
 Identities = 124/393 (31%), Positives = 213/393 (54%), Gaps = 13/393 (3%)

Query: 211 PEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMR------ 264
           P++L  ++ + G   PTPIQ Q  P+ L G D++  A TG+GKT ++L+P  +       
Sbjct: 231 PDLLK-SIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPI 289

Query: 265 ALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVK 324
           +  +   P  L+LTPTRELA+ +E +  +       +K++ + GG     Q+  + + V 
Sbjct: 290 SREQRNGPGMLVLTPTRELALHVEAECSKY--SYKGLKSICIYGGRNRNGQIEDISKGVD 347

Query: 325 VIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVS 384
           +IIATPGRL D+   +SV L  +  +V+DEAD ML M F+ Q+  IL ++  D QT++ S
Sbjct: 348 IIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTS 407

Query: 385 ATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFK 444
           AT P ++ QLA   L +P+ +  G  NL   N  +  + V    +K+ L +   +     
Sbjct: 408 ATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPN 467

Query: 445 PPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGV 504
             V++FV  K  AD LS     I G+ + S+H    Q +++  ++    G+ +++++T +
Sbjct: 468 DKVIMFVSQKHIADDLSSDF-NIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526

Query: 505 LGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRV 564
           + RGLDL  V  V N+D P ++D YVH++G +GR G+ GT++T I     ++  ++ K +
Sbjct: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586

Query: 565 KPTGSILPPQLL---NSPYLHDQKRKEQQKDKQ 594
                 +P  L+       L+ QKR  + + ++
Sbjct: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRK 619


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  204 bits (519), Expect = 2e-52
 Identities = 127/368 (34%), Positives = 203/368 (55%), Gaps = 11/368 (2%)

Query: 197 EVTRPIID------FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTG 250
           E ++PI++      F+   + +VL     + G+  PT IQ++ IP+ L GRDI+  A+TG
Sbjct: 12  EASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETG 71

Query: 251 SGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGL 310
           SGKT AF LP++   L   +   AL+LTPTRELA QI  Q + L S +  +++ ++VGG+
Sbjct: 72  SGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGI 130

Query: 311 PLPPQLYRLQQHVKVIIATPGRLLDIIKQS-SVELCGVKIVVVDEADTMLKMGFQQQVLD 369
               Q   L +   +IIATPGRL+D ++ +    L  +K +V+DEAD +L M F+ +V  
Sbjct: 131 DSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDK 190

Query: 370 ILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAK 429
           IL+ IP D +T L SAT+   +++L    L NPV+     K      ++Q  +++    K
Sbjct: 191 ILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFK 250

Query: 430 KKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILK 489
              L  ILN+  L     ++F          +  ++ + G  +I +H + SQ +R   L 
Sbjct: 251 DTYLVYILNE--LAGNSFMIFCSTCNNTQRTALLLRNL-GFTAIPLHGQMSQSKRLGSLN 307

Query: 490 GLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFI 549
                   ++++T V  RGLD+  V +VVNFD+P+   +Y+H++GR  R G++G AITF+
Sbjct: 308 KFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFV 367

Query: 550 NNNSKRLF 557
                 LF
Sbjct: 368 TQYDVELF 375


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  204 bits (518), Expect = 3e-52
 Identities = 137/455 (30%), Positives = 231/455 (50%), Gaps = 15/455 (3%)

Query: 132 KAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLK----- 186
           K K   +  E +E+  L    +  SE E+     Y   +   +      ++++ K     
Sbjct: 142 KEKEAKEGSEPKEQEDLQENDEEGSEDEAS-ETDYSSADENILTKADTLKVKDRKKKKKK 200

Query: 187 -QQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILA 245
            Q+ G   +        + F+  +L   L   +   G++ PTPIQ   IPVGLLG+DI A
Sbjct: 201 GQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICA 260

Query: 246 SADTGSGKTAAFLLPVIMRALFESK---TPSALILTPTRELAIQIERQAKELMSGLPRMK 302
            A TG+GKTAAF LPV+ R +++ +       L+L PTREL IQ+    ++L      + 
Sbjct: 261 CAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQ-FCNIT 319

Query: 303 TVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQS-SVELCGVKIVVVDEADTMLKM 361
           T L VGGL +  Q   L+    ++IATPGRL+D +    S  L  ++++++DEAD ML  
Sbjct: 320 TCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDE 379

Query: 362 GFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQII 421
            F++Q+ +I+    +  QT+L SAT+   ++ LAS  L NPVRI           +RQ  
Sbjct: 380 YFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEF 439

Query: 422 LWVEDPAK-KKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKS 480
           + +    +  ++        + F   V++F   K  A  +   +  + GL+   +H   S
Sbjct: 440 IRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRM-HILLGLMGLQVGELHGNLS 498

Query: 481 QIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLG 540
           Q +R   L+   +   +++V+T V  RGLD+  V+ V+NF MP+++  YVH++GR  R G
Sbjct: 499 QTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAG 558

Query: 541 QNGTAITFINNNSKRLFWDIAKRVK-PTGSILPPQ 574
           + G +++ +  + +++  +I K  K P  + + PQ
Sbjct: 559 RAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQ 593


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  196 bits (499), Expect = 4e-50
 Identities = 121/381 (31%), Positives = 201/381 (52%), Gaps = 8/381 (2%)

Query: 204 DFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIM 263
           +FE   L   L   + + G+E P+PIQ + IP+ L GRDILA A  G+GK+ A+L+P++ 
Sbjct: 97  EFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLE 156

Query: 264 RALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHV 323
           R   +     A+++ PTRELA+Q+ +   ++   +   K +   GG  L   + RL   V
Sbjct: 157 RLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTV 216

Query: 324 KVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILV 383
            V+IATPGR+LD+IK+   ++  V+++V+DEAD +L   F Q + DI+  +P + Q +L 
Sbjct: 217 HVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLY 276

Query: 384 SATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLF 443
           SAT P S+++  +  L  P  I   E+ L    V Q   +V +  K   L  + +  ++ 
Sbjct: 277 SATFPLSVQKFMNSHLQKPYEINLMEE-LTLKGVTQYYAYVTERQKVHCLNTLFSRLQIN 335

Query: 444 KPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTG 503
           +   ++F +     +LL++ + ++ G     IH++  Q  R  +      G    +V T 
Sbjct: 336 QS--IIFCNSSQRVELLAKKISQL-GYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD 392

Query: 504 VLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINN----NSKRLFWD 559
           +  RG+D+ +V +V+NFD P   + Y+H+IGR GR G  G AI  I      N K +   
Sbjct: 393 LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQ 452

Query: 560 IAKRVKPTGSILPPQLLNSPY 580
           +   +KP  S +   L  + Y
Sbjct: 453 LGTEIKPIPSNIDKSLYVAEY 473


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  196 bits (499), Expect = 4e-50
 Identities = 113/372 (30%), Positives = 205/372 (55%), Gaps = 8/372 (2%)

Query: 204 DFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIM 263
           +F+  +L E L   +   G+E P+ IQ + I   + G D++A A +G+GKTA F + ++ 
Sbjct: 34  NFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQ 93

Query: 264 RALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHV 323
           +   E K   AL+L PTRELA QI++    L   +        +GG  +  ++ +LQ   
Sbjct: 94  QLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHAC-IGGTNVRNEMQKLQAEA 152

Query: 324 K-VIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTIL 382
             +++ TPGR+ D++ +  +    +K+ V+DEAD ML  GF+ Q+ +I + +    Q +L
Sbjct: 153 PHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVL 212

Query: 383 VSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILND--K 440
           +SAT+PT + ++  + + +P+RI+  ++ L    ++Q  + VE   +++   + L D  +
Sbjct: 213 LSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVE---REEWKLDTLCDLYE 269

Query: 441 KLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVV 500
            L     ++F++ +   D L+E +       S ++H +  Q ER  I++    G   V++
Sbjct: 270 TLTITQAVIFLNTRRKVDWLTEKMHARDFTVS-ALHGDMDQKERDVIMREFRSGSSRVLI 328

Query: 501 STGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDI 560
           +T +L RG+D+  V LV+N+D+P++ + Y+H+IGR GR G+ G AI F+    KR+  DI
Sbjct: 329 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDI 388

Query: 561 AKRVKPTGSILP 572
                 T   +P
Sbjct: 389 ETFYNTTVEEMP 400


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  196 bits (497), Expect = 7e-50
 Identities = 113/363 (31%), Positives = 204/363 (56%), Gaps = 9/363 (2%)

Query: 202 IID-FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLP 260
           I+D F+  +L E L   +   G+E P+ IQ + I   + G D++A A +G+GKTA F + 
Sbjct: 30  IVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAIS 89

Query: 261 VIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQ 320
           ++ +   + K   AL+L PTRELA QI++    L   +        +GG  +  ++ +LQ
Sbjct: 90  ILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGA-SCHACIGGTNVRAEVQKLQ 148

Query: 321 QHVK-VIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQ 379
                +I+ TPGR+ D++ +  +    +K+ V+DEAD ML  GF+ Q+ DI + + ++ Q
Sbjct: 149 MEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQ 208

Query: 380 TILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILND 439
            +L+SAT+P+ + ++  + + +P+RI+  ++ L    +RQ  + VE   +++   + L D
Sbjct: 209 VVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVE---REEWKLDTLCD 265

Query: 440 --KKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYE 497
             + L     ++F++ +   D L+E +       S ++H +  Q ER  I++    G   
Sbjct: 266 LYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS-AMHGDMDQKERDVIMREFRSGSSR 324

Query: 498 VVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLF 557
           V+++T +L RG+D+  V LV+N+D+P++ + Y+H+IGR GR G+ G AI  +    KR  
Sbjct: 325 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTL 384

Query: 558 WDI 560
            DI
Sbjct: 385 RDI 387


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  188 bits (477), Expect = 1e-47
 Identities = 122/347 (35%), Positives = 187/347 (53%), Gaps = 4/347 (1%)

Query: 205 FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMR 264
           F+   L   +   + K GY+VPTPIQ + IPV L G+D++A A TGSGKTA FLLP+  R
Sbjct: 98  FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157

Query: 265 ALFESKTPSA--LILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQH 322
               S    A  LIL+PTRELA+Q  +  KEL      +KT L++GG  +  Q   L ++
Sbjct: 158 LKTHSAQTGARALILSPTRELALQTLKFTKEL-GKFTGLKTALILGGDRMEDQFAALHEN 216

Query: 323 VKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTIL 382
             +IIATPGRL+ +  + S++L  V+ VV DEAD + +MGF +Q+ +I+  +P   QT+L
Sbjct: 217 PDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVL 276

Query: 383 VSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKL 442
            SAT+P  + + A   L  PV I           ++     V +  K   L  +L++   
Sbjct: 277 FSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVVR 336

Query: 443 FKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVST 502
            +   +VFV  K  A+ L+E +     +    I+S      RK  L     G    ++ T
Sbjct: 337 PQDQTVVFVATKHHAEYLTELL-TTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVT 395

Query: 503 GVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFI 549
            +  RGLD+  +  V+N+  P+    ++H++GRV R G++GTA + +
Sbjct: 396 DLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLV 442


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  188 bits (477), Expect = 1e-47
 Identities = 122/347 (35%), Positives = 187/347 (53%), Gaps = 4/347 (1%)

Query: 205 FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMR 264
           F+   L   +   + K GY+VPTPIQ + IPV L G+D++A A TGSGKTA FLLP+  R
Sbjct: 98  FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157

Query: 265 ALFESKTPSA--LILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQH 322
               S    A  LIL+PTRELA+Q  +  KEL      +KT L++GG  +  Q   L ++
Sbjct: 158 LKTHSAQTGARALILSPTRELALQTLKFTKEL-GKFTGLKTALILGGDRMEDQFAALHEN 216

Query: 323 VKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTIL 382
             +IIATPGRL+ +  + S++L  V+ VV DEAD + +MGF +Q+ +I+  +P   QT+L
Sbjct: 217 PDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVL 276

Query: 383 VSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKL 442
            SAT+P  + + A   L  PV I           ++     V +  K   L  +L++   
Sbjct: 277 FSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVVR 336

Query: 443 FKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVST 502
            +   +VFV  K  A+ L+E +     +    I+S      RK  L     G    ++ T
Sbjct: 337 PQDQTVVFVATKHHAEYLTELL-TTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVT 395

Query: 503 GVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFI 549
            +  RGLD+  +  V+N+  P+    ++H++GRV R G++GTA + +
Sbjct: 396 DLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLV 442


>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
           sapiens]
          Length = 427

 Score =  181 bits (459), Expect = 2e-45
 Identities = 114/383 (29%), Positives = 206/383 (53%), Gaps = 16/383 (4%)

Query: 211 PEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESK 270
           PE+L   +   G+E P+ +Q + IP  +LG D+L  A +G GKTA F+L  + +    + 
Sbjct: 53  PELLRA-IVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNG 111

Query: 271 TPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVK-VIIAT 329
             + L++  TRELA QI ++ +     +P +K  +  GGL +      L+++   V++ T
Sbjct: 112 QVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCPHVVVGT 171

Query: 330 PGRLLDIIKQSSVELCGVKIVVVDEADTMLK-MGFQQQVLDILENIPNDCQTILVSATIP 388
           PGR+L +++  S  L  VK  V+DE D ML+ +  ++ V +I    P++ Q ++ SAT+ 
Sbjct: 172 PGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLS 231

Query: 389 TSIEQLASQLLHNPVRI-ITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFKPPV 447
             I  +  + + +P+ + +  E  L    ++Q  + ++D  K +KLF++L+  +  +  V
Sbjct: 232 KDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQ--V 289

Query: 448 LVFVD----CKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTG 503
           ++FV     C   A LL E         +I+IH   +Q ER +  +   +    ++V+T 
Sbjct: 290 IIFVKSVQRCMALAQLLVEQ-----NFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATN 344

Query: 504 VLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINN-NSKRLFWDIAK 562
           + GRG+D+  V +V N+DMP   D Y+H++ R GR G  G AITF+++ N  ++  D+  
Sbjct: 345 LFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 404

Query: 563 RVKPTGSILPPQLLNSPYLHDQK 585
           R +   + LP ++  S Y+   +
Sbjct: 405 RFEVNVAELPEEIDISTYIEQSR 427


>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
           [Homo sapiens]
          Length = 406

 Score =  181 bits (458), Expect = 2e-45
 Identities = 119/368 (32%), Positives = 188/368 (51%), Gaps = 60/368 (16%)

Query: 197 EVTRPIID------FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTG 250
           E ++PI++      F+   + +VL     + G+  PT IQ++ IP+ L GRDI+  A+TG
Sbjct: 12  EASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETG 71

Query: 251 SGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGL 310
           SGKT AF LP++   L   +   AL+LTPTRELA QI  Q + L S +  +++ ++VGG+
Sbjct: 72  SGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGI 130

Query: 311 PLPPQLYRLQQHVKVIIATPGRLLDIIKQS-SVELCGVKIVVVDEADTMLKMGFQQQVLD 369
               Q   L +   +IIATPGRL+D ++ +    L  +K +V+DEAD +L M F+ +V  
Sbjct: 131 DSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDK 190

Query: 370 ILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAK 429
           IL+ IP D +T L SAT+   +++L    L NPV+     K      ++Q  +++    K
Sbjct: 191 ILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFK 250

Query: 430 KKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILK 489
            K+L  +                                          K + + ++IL 
Sbjct: 251 SKRLGSL-----------------------------------------NKFKAKARSIL- 268

Query: 490 GLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFI 549
                     ++T V  RGLD+  V +VVNFD+P+   +Y+H++GR  R G++G AITF+
Sbjct: 269 ----------LATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFV 318

Query: 550 NNNSKRLF 557
                 LF
Sbjct: 319 TQYDVELF 326


>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score =  179 bits (455), Expect = 5e-45
 Identities = 120/426 (28%), Positives = 218/426 (51%), Gaps = 21/426 (4%)

Query: 174 ILNLQEDQIENLKQQLGIL------VQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPT 227
           +L+ ++D++E      G        V+G  V+     F    L   L   +   G+E P+
Sbjct: 10  LLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPS 69

Query: 228 PIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQI 287
            +Q + IP  +LG D+L  A +G GKTA F+L  + +    +   S L++  TRELA QI
Sbjct: 70  EVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQI 129

Query: 288 ERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHV-KVIIATPGRLLDIIKQSSVELCG 346
            ++ +     +P +K  +  GGL +      L+++   +++ TPGR+L + +  S+ L  
Sbjct: 130 SKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKH 189

Query: 347 VKIVVVDEADTML-KMGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRI 405
           +K  ++DE D ML ++  ++ V +I    P++ Q ++ SAT+   I  +  + + +P+ I
Sbjct: 190 IKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEI 249

Query: 406 -ITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFKPPVLVFVD----CKLGADLL 460
            +  E  L    ++Q  + ++D  K +KLF++L+  +  +  V++FV     C   A LL
Sbjct: 250 FVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQ--VVIFVKSVQRCIALAQLL 307

Query: 461 SEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNF 520
            E         +I+IH    Q ER +  +   +    ++V+T + GRG+D+  V +  N+
Sbjct: 308 VE-----QNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNY 362

Query: 521 DMPSSMDEYVHQIGRVGRLGQNGTAITFINN-NSKRLFWDIAKRVKPTGSILPPQLLNSP 579
           DMP   D Y+H++ R GR G  G AITF+++ N  ++  D+  R +   S LP ++  S 
Sbjct: 363 DMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDISS 422

Query: 580 YLHDQK 585
           Y+   +
Sbjct: 423 YIEQTR 428


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,417,712
Number of Sequences: 37866
Number of extensions: 1160503
Number of successful extensions: 3959
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 3680
Number of HSP's gapped (non-prelim): 128
length of query: 619
length of database: 18,247,518
effective HSP length: 108
effective length of query: 511
effective length of database: 14,157,990
effective search space: 7234732890
effective search space used: 7234732890
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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