Guide to the Human Genome
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Search of human proteins with 187960047

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|187960047 angiopoietin-like 5 [Homo sapiens]
         (388 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187960047 angiopoietin-like 5 [Homo sapiens]                       812   0.0  
gi|4757752 angiopoietin-like 1 precursor [Homo sapiens]               150   2e-36
gi|5730075 fibrinogen-like 2 precursor [Homo sapiens]                 147   2e-35
gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]               144   2e-34
gi|42544202 fibrinogen-like 1 precursor [Homo sapiens]                140   3e-33
gi|42544200 fibrinogen-like 1 precursor [Homo sapiens]                140   3e-33
gi|42544198 fibrinogen-like 1 precursor [Homo sapiens]                140   3e-33
gi|42544189 fibrinogen-like 1 precursor [Homo sapiens]                140   3e-33
gi|20532340 angiopoietin 1 [Homo sapiens]                             131   9e-31
gi|169646749 angiopoietin 2 isoform b precursor [Homo sapiens]        131   1e-30
gi|169646754 angiopoietin 2 isoform c precursor [Homo sapiens]        130   2e-30
gi|4557315 angiopoietin 2 isoform a precursor [Homo sapiens]          130   2e-30
gi|10863949 angiopoietin-like 7 [Homo sapiens]                        129   4e-30
gi|70906439 fibrinogen, gamma chain isoform gamma-B precursor [H...   128   8e-30
gi|70906437 fibrinogen, gamma chain isoform gamma-A precursor [H...   128   8e-30
gi|62988324 tenascin N [Homo sapiens]                                 126   4e-29
gi|7705276 angiopoietin 4 [Homo sapiens]                              124   1e-28
gi|223029463 fibrinogen C domain containing 1 [Homo sapiens]          121   9e-28
gi|223029461 fibrinogen C domain containing 1 [Homo sapiens]          121   9e-28
gi|70906435 fibrinogen, beta chain preproprotein [Homo sapiens]       121   9e-28
gi|157384973 tenascin R [Homo sapiens]                                119   6e-27
gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E preprop...   116   3e-26
gi|8051586 ficolin 2 isoform b precursor [Homo sapiens]               114   1e-25
gi|61744445 ficolin 2 isoform a precursor [Homo sapiens]              114   1e-25
gi|29893555 angiopoietin-like 6 [Homo sapiens]                        112   4e-25
gi|23111005 microfibrillar-associated protein 4 [Homo sapiens]        112   6e-25
gi|8051584 ficolin 1 precursor [Homo sapiens]                         110   3e-24
gi|20665034 tenascin XB isoform 2 [Homo sapiens]                      108   1e-23
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]           108   1e-23
gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens]              102   8e-22

>gi|187960047 angiopoietin-like 5 [Homo sapiens]
          Length = 388

 Score =  812 bits (2098), Expect = 0.0
 Identities = 388/388 (100%), Positives = 388/388 (100%)

Query: 1   MMSPSQASLLFLNVCIFICGEAVQGNCVHHSTDSSVVNIVEDGSNAKDESKSNDTVCKED 60
           MMSPSQASLLFLNVCIFICGEAVQGNCVHHSTDSSVVNIVEDGSNAKDESKSNDTVCKED
Sbjct: 1   MMSPSQASLLFLNVCIFICGEAVQGNCVHHSTDSSVVNIVEDGSNAKDESKSNDTVCKED 60

Query: 61  CEESCDVKTKITREEKHFMCRNLQNSIVSYTRSTKKLLRNMMDEQQASLDYLSNQVNELM 120
           CEESCDVKTKITREEKHFMCRNLQNSIVSYTRSTKKLLRNMMDEQQASLDYLSNQVNELM
Sbjct: 61  CEESCDVKTKITREEKHFMCRNLQNSIVSYTRSTKKLLRNMMDEQQASLDYLSNQVNELM 120

Query: 121 NRVLLLTTEVFRKQLDPFPHRPVQSHGLDCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFE 180
           NRVLLLTTEVFRKQLDPFPHRPVQSHGLDCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFE
Sbjct: 121 NRVLLLTTEVFRKQLDPFPHRPVQSHGLDCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFE 180

Query: 181 VMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTS 240
           VMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTS
Sbjct: 181 VMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTS 240

Query: 241 FMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPF 300
           FMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPF
Sbjct: 241 FMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPF 300

Query: 301 STSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKLLATGIQW 360
           STSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKLLATGIQW
Sbjct: 301 STSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKLLATGIQW 360

Query: 361 GTWTKNNSPVKIKSVSMKIRRMYNPYFK 388
           GTWTKNNSPVKIKSVSMKIRRMYNPYFK
Sbjct: 361 GTWTKNNSPVKIKSVSMKIRRMYNPYFK 388


>gi|4757752 angiopoietin-like 1 precursor [Homo sapiens]
          Length = 491

 Score =  150 bits (378), Expect = 2e-36
 Identities = 87/235 (37%), Positives = 124/235 (52%), Gaps = 28/235 (11%)

Query: 149 DCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRL 208
           DC   K+   SV    SG+Y+I PE S+ P ++ C+     GG TVIQKR DG ++F R 
Sbjct: 279 DCQQAKEAGHSV----SGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRN 334

Query: 209 WCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDET 268
           W +Y  GFG++ GE+WLGL+ I+ + NQ N  + L + LE   D   YA Y +F LE E+
Sbjct: 335 WENYKKGFGNIDGEYWLGLENIYMLSNQDN--YKLLIELEDWSDKKVYAEYSSFRLEPES 392

Query: 269 RFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLH 328
            F+++ LG Y GNAGD+          N   F+T D D D              +C+H H
Sbjct: 393 EFYRLRLGTYQGNAGDSMMW------HNGKQFTTLDRDKD----------MYAGNCAHFH 436

Query: 329 NKTGWWFNECGLANLNGIHHFSGKLLA---TGIQWGTWTKNNSPVKIKSVSMKIR 380
            K GWW+N C  +NLNG+ +  G   +    GI W  +        +++V M I+
Sbjct: 437 -KGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEY--RGGSYSLRAVQMMIK 488


>gi|5730075 fibrinogen-like 2 precursor [Homo sapiens]
          Length = 439

 Score =  147 bits (370), Expect = 2e-35
 Identities = 101/297 (34%), Positives = 149/297 (50%), Gaps = 33/297 (11%)

Query: 98  LRNMMDEQQASLDYLSNQVNELMNRVLLLTTEVFRKQLDPFPHRPVQSHGL--DCTDIKD 155
           + N +D + A+L ++ N ++   ++             +    RPVQ H +  DC+D   
Sbjct: 169 IENYVDSKVANLTFVVNSLDGKCSKC---------PSQEQIQSRPVQ-HLIYKDCSDYY- 217

Query: 156 TIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDG 215
              ++ K  S  Y + P+  +  FEV CDM+  GGG TV+Q R+DG  +F R W DY  G
Sbjct: 218 ---AIGKRSSETYRVTPDPKNSSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQDYKAG 274

Query: 216 FGDLLGEFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHL 275
           FG+L  EFWLG  KI  +   K+   +L + LE  +    YA YD F++ +E   +++H+
Sbjct: 275 FGNLRREFWLGNDKIHLLT--KSKEMILRIDLEDFNGVELYALYDQFYVANEFLKYRLHV 332

Query: 276 GRYSGNAGDAFRGLKKEDNQNAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWF 335
           G Y+G AGDA R   K  N +   F+T D DND              +C  L+  +GWWF
Sbjct: 333 GNYNGTAGDALR-FNKHYNHDLKFFTTPDKDNDRYPSG---------NCG-LYYSSGWWF 381

Query: 336 NECGLANLNG-IHHFSGKLLATGIQWGTW--TKNNSPVKIKSVSMKIRRMYNP-YFK 388
           + C  ANLNG  +H   + +  GI WGTW       P   KS   + + M  P +FK
Sbjct: 382 DACLSANLNGKYYHQKYRGVRNGIFWGTWPGVSEAHPGGYKSSFKEAKMMIRPKHFK 438


>gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]
          Length = 493

 Score =  144 bits (362), Expect = 2e-34
 Identities = 81/225 (36%), Positives = 123/225 (54%), Gaps = 24/225 (10%)

Query: 165 SGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFW 224
           S +Y++ PE ++   +V CD  +  GG TVIQ+R+DG ++F R W  Y  GFG++ GE+W
Sbjct: 289 SSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYW 348

Query: 225 LGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGD 284
           LGL+ I+++ NQ N  + L V +E       +A Y +F LE E+ ++K+ LGRY GNAGD
Sbjct: 349 LGLENIYWLTNQGN--YKLLVTMEDWSGRKVFAEYASFRLEPESEYYKLRLGRYHGNAGD 406

Query: 285 AFRGLKKEDNQNAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLN 344
           +F         N   F+T D D+D      +  G    +C+H + K GWW+N C  +NLN
Sbjct: 407 SFTW------HNGKQFTTLDRDHD------VYTG----NCAH-YQKGGWWYNACAHSNLN 449

Query: 345 GIHHFSGKLLA---TGIQWGTWTKNNSPVKIKSVSMKIRRMYNPY 386
           G+ +  G   +    G+ W  +        +K V M IR   N +
Sbjct: 450 GVWYRGGHYRSRYQDGVYWAEF--RGGSYSLKKVVMMIRPNPNTF 492


>gi|42544202 fibrinogen-like 1 precursor [Homo sapiens]
          Length = 312

 Score =  140 bits (352), Expect = 3e-33
 Identities = 91/227 (40%), Positives = 119/227 (52%), Gaps = 28/227 (12%)

Query: 165 SGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLL---G 221
           SG Y I P  S   F V CDM   GGG TVIQ+R DG  +F R W DY +GFG+ +   G
Sbjct: 94  SGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQKHG 152

Query: 222 EFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGN 281
           E+WLG K + ++  Q++  + L + L   +    YA Y NF + DE  F+++++G YSG 
Sbjct: 153 EYWLGNKNLHFLTTQED--YTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGT 210

Query: 282 AGDAFRGLKKEDNQ-----NAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFN 336
           AGD+  G    + Q       M FST D D+D     C    QS           GWWFN
Sbjct: 211 AGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQS-----------GWWFN 259

Query: 337 ECGLANLNGIHHFSGKLLA---TGIQWGTWTKNNSPVKIKSVSMKIR 380
            C  ANLNG+ ++SG   A    GI W TW  +     +KSV MKIR
Sbjct: 260 RCHSANLNGV-YYSGPYTAKTDNGIVWYTW--HGWWYSLKSVVMKIR 303


>gi|42544200 fibrinogen-like 1 precursor [Homo sapiens]
          Length = 312

 Score =  140 bits (352), Expect = 3e-33
 Identities = 91/227 (40%), Positives = 119/227 (52%), Gaps = 28/227 (12%)

Query: 165 SGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLL---G 221
           SG Y I P  S   F V CDM   GGG TVIQ+R DG  +F R W DY +GFG+ +   G
Sbjct: 94  SGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQKHG 152

Query: 222 EFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGN 281
           E+WLG K + ++  Q++  + L + L   +    YA Y NF + DE  F+++++G YSG 
Sbjct: 153 EYWLGNKNLHFLTTQED--YTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGT 210

Query: 282 AGDAFRGLKKEDNQ-----NAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFN 336
           AGD+  G    + Q       M FST D D+D     C    QS           GWWFN
Sbjct: 211 AGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQS-----------GWWFN 259

Query: 337 ECGLANLNGIHHFSGKLLA---TGIQWGTWTKNNSPVKIKSVSMKIR 380
            C  ANLNG+ ++SG   A    GI W TW  +     +KSV MKIR
Sbjct: 260 RCHSANLNGV-YYSGPYTAKTDNGIVWYTW--HGWWYSLKSVVMKIR 303


>gi|42544198 fibrinogen-like 1 precursor [Homo sapiens]
          Length = 312

 Score =  140 bits (352), Expect = 3e-33
 Identities = 91/227 (40%), Positives = 119/227 (52%), Gaps = 28/227 (12%)

Query: 165 SGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLL---G 221
           SG Y I P  S   F V CDM   GGG TVIQ+R DG  +F R W DY +GFG+ +   G
Sbjct: 94  SGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQKHG 152

Query: 222 EFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGN 281
           E+WLG K + ++  Q++  + L + L   +    YA Y NF + DE  F+++++G YSG 
Sbjct: 153 EYWLGNKNLHFLTTQED--YTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGT 210

Query: 282 AGDAFRGLKKEDNQ-----NAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFN 336
           AGD+  G    + Q       M FST D D+D     C    QS           GWWFN
Sbjct: 211 AGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQS-----------GWWFN 259

Query: 337 ECGLANLNGIHHFSGKLLA---TGIQWGTWTKNNSPVKIKSVSMKIR 380
            C  ANLNG+ ++SG   A    GI W TW  +     +KSV MKIR
Sbjct: 260 RCHSANLNGV-YYSGPYTAKTDNGIVWYTW--HGWWYSLKSVVMKIR 303


>gi|42544189 fibrinogen-like 1 precursor [Homo sapiens]
          Length = 312

 Score =  140 bits (352), Expect = 3e-33
 Identities = 91/227 (40%), Positives = 119/227 (52%), Gaps = 28/227 (12%)

Query: 165 SGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLL---G 221
           SG Y I P  S   F V CDM   GGG TVIQ+R DG  +F R W DY +GFG+ +   G
Sbjct: 94  SGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQKHG 152

Query: 222 EFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGN 281
           E+WLG K + ++  Q++  + L + L   +    YA Y NF + DE  F+++++G YSG 
Sbjct: 153 EYWLGNKNLHFLTTQED--YTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGT 210

Query: 282 AGDAFRGLKKEDNQ-----NAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFN 336
           AGD+  G    + Q       M FST D D+D     C    QS           GWWFN
Sbjct: 211 AGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQS-----------GWWFN 259

Query: 337 ECGLANLNGIHHFSGKLLA---TGIQWGTWTKNNSPVKIKSVSMKIR 380
            C  ANLNG+ ++SG   A    GI W TW  +     +KSV MKIR
Sbjct: 260 RCHSANLNGV-YYSGPYTAKTDNGIVWYTW--HGWWYSLKSVVMKIR 303


>gi|20532340 angiopoietin 1 [Homo sapiens]
          Length = 498

 Score =  131 bits (330), Expect = 9e-31
 Identities = 102/315 (32%), Positives = 149/315 (47%), Gaps = 40/315 (12%)

Query: 73  REEKHFMCRNLQNSIVSYTRSTKKLLRNMMDEQQASLDYLSNQVNELM----NRVLLLTT 128
           +EEK     NLQ  +   T   ++L    ++    +   L  Q  ELM    N V L T 
Sbjct: 213 KEEKE----NLQGLVTRQTYIIQEL-EKQLNRATTNNSVLQKQQLELMDTVHNLVNLCTK 267

Query: 129 E-VFRKQLDPFPHRPVQSHGLDCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDY 187
           E V  K       +P +    DC D+           SG+Y I+      P +V C+MD 
Sbjct: 268 EGVLLKGGKREEEKPFR----DCADVYQA----GFNKSGIYTIYINNMPEPKKVFCNMDV 319

Query: 188 RGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTSFMLYVAL 247
            GGG TVIQ R DG +DFQR W +Y  GFG+  GE+WLG + IF I +Q+   +ML + L
Sbjct: 320 NGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQR--QYMLRIEL 377

Query: 248 ESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPFSTSDVDN 307
              +   AY+ YD F + +E + ++++L  ++G AG      +     +   FST D DN
Sbjct: 378 MDWEGNRAYSQYDRFHIGNEKQNYRLYLKGHTGTAGK-----QSSLILHGADFSTKDADN 432

Query: 308 DGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKL--LATGIQWGTWTK 365
           D C   C            L    GWWF+ CG +NLNG+ + +G+      GI+W  +  
Sbjct: 433 DNCMCKCA-----------LMLTGGWWFDACGPSNLNGMFYTAGQNHGKLNGIKWHYF-- 479

Query: 366 NNSPVKIKSVSMKIR 380
                 ++S +M IR
Sbjct: 480 KGPSYSLRSTTMMIR 494


>gi|169646749 angiopoietin 2 isoform b precursor [Homo sapiens]
          Length = 495

 Score =  131 bits (329), Expect = 1e-30
 Identities = 88/272 (32%), Positives = 135/272 (49%), Gaps = 27/272 (9%)

Query: 112 LSNQVNELMNRVL-LLTTEVFRKQLDPFPHRPVQSHGLDCTDIKDTIGSVTKTPSGLYII 170
           L  Q ++LM  V  LLT        DP   +  Q    DC ++  +      T +G+Y +
Sbjct: 244 LQKQQHDLMETVNNLLTMMSTSNSKDPTVAKEEQISFRDCAEVFKS----GHTTNGIYTL 299

Query: 171 HPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKI 230
               S+   +  CDM+  GGG T+IQ+R DG +DFQR W +Y  GFG+  GE+WLG + +
Sbjct: 300 TFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEFV 359

Query: 231 FYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGLK 290
             + NQ+   ++L + L+  +   AY+ Y++F+L  E   +++HL   +G AG       
Sbjct: 360 SQLTNQQR--YVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKI----- 412

Query: 291 KEDNQNAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHH-- 348
              +Q    FST D DND C          +  CS +    GWWF+ CG +NLNG+++  
Sbjct: 413 SSISQPGNDFSTKDGDNDKC----------ICKCSQMLT-GGWWFDACGPSNLNGMYYPQ 461

Query: 349 FSGKLLATGIQWGTWTKNNSPVKIKSVSMKIR 380
                   GI+W  W    S   +K+ +M IR
Sbjct: 462 RQNTNKFNGIKWYYW--KGSGYSLKATTMMIR 491


>gi|169646754 angiopoietin 2 isoform c precursor [Homo sapiens]
          Length = 444

 Score =  130 bits (328), Expect = 2e-30
 Identities = 87/273 (31%), Positives = 134/273 (49%), Gaps = 28/273 (10%)

Query: 112 LSNQVNELMNRV--LLLTTEVFRKQLDPFPHRPVQSHGLDCTDIKDTIGSVTKTPSGLYI 169
           L  Q ++LM  V  LL          DP   +  Q    DC ++  +      T +G+Y 
Sbjct: 192 LQKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQISFRDCAEVFKS----GHTTNGIYT 247

Query: 170 IHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKK 229
           +    S+   +  CDM+  GGG T+IQ+R DG +DFQR W +Y  GFG+  GE+WLG + 
Sbjct: 248 LTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEF 307

Query: 230 IFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGL 289
           +  + NQ+   ++L + L+  +   AY+ Y++F+L  E   +++HL   +G AG      
Sbjct: 308 VSQLTNQQR--YVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKI---- 361

Query: 290 KKEDNQNAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHH- 348
               +Q    FST D DND C          +  CS +    GWWF+ CG +NLNG+++ 
Sbjct: 362 -SSISQPGNDFSTKDGDNDKC----------ICKCSQMLT-GGWWFDACGPSNLNGMYYP 409

Query: 349 -FSGKLLATGIQWGTWTKNNSPVKIKSVSMKIR 380
                    GI+W  W    S   +K+ +M IR
Sbjct: 410 QRQNTNKFNGIKWYYW--KGSGYSLKATTMMIR 440


>gi|4557315 angiopoietin 2 isoform a precursor [Homo sapiens]
          Length = 496

 Score =  130 bits (328), Expect = 2e-30
 Identities = 87/273 (31%), Positives = 134/273 (49%), Gaps = 28/273 (10%)

Query: 112 LSNQVNELMNRV--LLLTTEVFRKQLDPFPHRPVQSHGLDCTDIKDTIGSVTKTPSGLYI 169
           L  Q ++LM  V  LL          DP   +  Q    DC ++  +      T +G+Y 
Sbjct: 244 LQKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQISFRDCAEVFKS----GHTTNGIYT 299

Query: 170 IHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKK 229
           +    S+   +  CDM+  GGG T+IQ+R DG +DFQR W +Y  GFG+  GE+WLG + 
Sbjct: 300 LTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEF 359

Query: 230 IFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGL 289
           +  + NQ+   ++L + L+  +   AY+ Y++F+L  E   +++HL   +G AG      
Sbjct: 360 VSQLTNQQR--YVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKI---- 413

Query: 290 KKEDNQNAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHH- 348
               +Q    FST D DND C          +  CS +    GWWF+ CG +NLNG+++ 
Sbjct: 414 -SSISQPGNDFSTKDGDNDKC----------ICKCSQMLT-GGWWFDACGPSNLNGMYYP 461

Query: 349 -FSGKLLATGIQWGTWTKNNSPVKIKSVSMKIR 380
                    GI+W  W    S   +K+ +M IR
Sbjct: 462 QRQNTNKFNGIKWYYW--KGSGYSLKATTMMIR 492


>gi|10863949 angiopoietin-like 7 [Homo sapiens]
          Length = 346

 Score =  129 bits (324), Expect = 4e-30
 Identities = 97/337 (28%), Positives = 154/337 (45%), Gaps = 59/337 (17%)

Query: 61  CEESCDVKTKIT-----------REEKHFMCRNLQNSIVSYTRSTKKLLRNMMDEQQASL 109
           CEE  ++K ++            ++E+ ++   +Q   V    S  K + + + + ++  
Sbjct: 46  CEEVKELKAQVANLSSLLSELNKKQERDWVSVVMQ---VMELESNSKRMESRLTDAESKY 102

Query: 110 DYLSNQVNELMNRVLLLTTEVFRKQLDPFPHRPVQSHGLDCTDIKDT---IGSVTKTPSG 166
             ++NQ++ +  +     T+     +             DC+ +      I  V K P  
Sbjct: 103 SEMNNQIDIMQLQAAQTVTQTSADAI------------YDCSSLYQKNYRISGVYKLPPD 150

Query: 167 LYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLG 226
            ++  PE      EV CDM+  GGG T+IQ+R  G++ F R W  Y  GFG + G+FWLG
Sbjct: 151 DFLGSPE-----LEVFCDMETSGGGWTIIQRRKSGLVSFYRDWKQYKQGFGSIRGDFWLG 205

Query: 227 LKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAG-DA 285
            + I  +  Q      L V +E  +  L YA Y +F L +E   +++ LG Y+GN G DA
Sbjct: 206 NEHIHRLSRQPT---RLRVEMEDWEGNLRYAEYSHFVLGNELNSYRLFLGNYTGNVGNDA 262

Query: 286 FRGLKKEDNQNAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNG 345
            +        N   FST D DND C          +  C+ L  K G+W+N C  +NLNG
Sbjct: 263 LQ------YHNNTAFSTKDKDNDNC----------LDKCAQL-RKGGYWYNCCTDSNLNG 305

Query: 346 IHHFSGK--LLATGIQWGTWTKNNSPVKIKSVSMKIR 380
           +++  G+      GI W  W  + S   +K V MKIR
Sbjct: 306 VYYRLGEHNKHLDGITWYGW--HGSTYSLKRVEMKIR 340


>gi|70906439 fibrinogen, gamma chain isoform gamma-B precursor [Homo
           sapiens]
          Length = 453

 Score =  128 bits (322), Expect = 8e-30
 Identities = 102/326 (31%), Positives = 145/326 (44%), Gaps = 47/326 (14%)

Query: 85  NSIVSYTRSTKKLLRNMMDEQ------QASLDYLSNQVNELMNRVLLLTTEVFRKQLDPF 138
           N I + T  ++K+L  +M  +       +S+ YL    N    +++ L  +V   QL+  
Sbjct: 103 NMIDAATLKSRKMLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKV--AQLEAQ 160

Query: 139 PHRP----VQSHGLDCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGRTV 194
              P    VQ H +   D +D      K  SGLY I P  ++  F V C++D  G G TV
Sbjct: 161 CQEPCKDTVQIHDITGKDCQDIANKGAKQ-SGLYFIKPLKANQQFLVYCEIDGSGNGWTV 219

Query: 195 IQKRIDGIIDFQRLWCDYLDGFGDL----LGEFWLGLKKIFYIVNQKNTSFMLYVALESE 250
            QKR+DG +DF++ W  Y +GFG L      EFWLG +KI  I  Q    + L V LE  
Sbjct: 220 FQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDW 279

Query: 251 DDTLAYASYDNFWLEDETRFFKMHLGRYS-GNAGDAFRGLKKED--------NQNAMPFS 301
           +   + A Y  F +  E   +++    ++ G+AGDAF G    D        + N M FS
Sbjct: 280 NGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFS 339

Query: 302 TSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKL-------- 353
           T D DND     C     S           GWW N+C   +LNG+++  G          
Sbjct: 340 TWDNDNDKFEGNCAEQDGS-----------GWWMNKCHAGHLNGVYYQGGTYSKASTPNG 388

Query: 354 LATGIQWGTWTKNNSPVKIKSVSMKI 379
              GI W TW        +K  +MKI
Sbjct: 389 YDNGIIWATW--KTRWYSMKKTTMKI 412


>gi|70906437 fibrinogen, gamma chain isoform gamma-A precursor [Homo
           sapiens]
          Length = 437

 Score =  128 bits (322), Expect = 8e-30
 Identities = 102/326 (31%), Positives = 145/326 (44%), Gaps = 47/326 (14%)

Query: 85  NSIVSYTRSTKKLLRNMMDEQ------QASLDYLSNQVNELMNRVLLLTTEVFRKQLDPF 138
           N I + T  ++K+L  +M  +       +S+ YL    N    +++ L  +V   QL+  
Sbjct: 103 NMIDAATLKSRKMLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKV--AQLEAQ 160

Query: 139 PHRP----VQSHGLDCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGRTV 194
              P    VQ H +   D +D      K  SGLY I P  ++  F V C++D  G G TV
Sbjct: 161 CQEPCKDTVQIHDITGKDCQDIANKGAKQ-SGLYFIKPLKANQQFLVYCEIDGSGNGWTV 219

Query: 195 IQKRIDGIIDFQRLWCDYLDGFGDL----LGEFWLGLKKIFYIVNQKNTSFMLYVALESE 250
            QKR+DG +DF++ W  Y +GFG L      EFWLG +KI  I  Q    + L V LE  
Sbjct: 220 FQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDW 279

Query: 251 DDTLAYASYDNFWLEDETRFFKMHLGRYS-GNAGDAFRGLKKED--------NQNAMPFS 301
           +   + A Y  F +  E   +++    ++ G+AGDAF G    D        + N M FS
Sbjct: 280 NGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFS 339

Query: 302 TSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKL-------- 353
           T D DND     C     S           GWW N+C   +LNG+++  G          
Sbjct: 340 TWDNDNDKFEGNCAEQDGS-----------GWWMNKCHAGHLNGVYYQGGTYSKASTPNG 388

Query: 354 LATGIQWGTWTKNNSPVKIKSVSMKI 379
              GI W TW        +K  +MKI
Sbjct: 389 YDNGIIWATW--KTRWYSMKKTTMKI 412


>gi|62988324 tenascin N [Homo sapiens]
          Length = 1299

 Score =  126 bits (316), Expect = 4e-29
 Identities = 79/236 (33%), Positives = 118/236 (50%), Gaps = 27/236 (11%)

Query: 146  HGLDCTDIKDTIGSVTKTPSGLYIIHPEG-SSYPFEVMCDMDYRGGGRTVIQKRIDGIID 204
            H  DC+ ++      +   SGLY I+  G +S P +V CDM+  GGG  V Q+R  G +D
Sbjct: 1066 HPSDCSQVQQN----SNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLD 1121

Query: 205  FQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWL 264
            F + W  Y++GFGD + EFWLGL K+  +       + + V L++ +++ AYA YD F +
Sbjct: 1122 FFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQTANES-AYAIYDFFQV 1180

Query: 265  EDETRFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPFSTSDVDNDGCRPACLVNGQSVKSC 324
                  +K+ +G+Y G AGDA          N   F+T D DND           ++ +C
Sbjct: 1181 ASSKERYKLTVGKYRGTAGDAL------TYHNGWKFTTFDRDND----------IALSNC 1224

Query: 325  SHLHNKTGWWFNECGLANLNGIHHFSGKLLATGIQWGTWTKNNSPVKIKSVSMKIR 380
            +  H+  GWW+  C LAN NG   +     + G+ W  W        I  V +KIR
Sbjct: 1225 ALTHH-GGWWYKNCHLANPNG--RYGETKHSEGVNWEPW--KGHEFSIPYVELKIR 1275


>gi|7705276 angiopoietin 4 [Homo sapiens]
          Length = 503

 Score =  124 bits (312), Expect = 1e-28
 Identities = 74/216 (34%), Positives = 116/216 (53%), Gaps = 28/216 (12%)

Query: 149 DCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRL 208
           DC +I+ +  S     SG+Y I    ++ P +V CD+   GG  T+IQ+R +G ++FQR 
Sbjct: 290 DCAEIQRSGASA----SGVYTIQVSNATKPRKVFCDLQSSGGRWTLIQRRENGTVNFQRN 345

Query: 209 WCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDET 268
           W DY  GFGD  GE WLG + +  +   +  ++ L V L+  +   AYA Y++F L  E 
Sbjct: 346 WKDYKQGFGDPAGEHWLGNEVVHQLT--RRAAYSLRVELQDWEGHEAYAQYEHFHLGSEN 403

Query: 269 RFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPFSTSDVDNDGCRPAC--LVNGQSVKSCSH 326
           + +++ +  YSG+AG     + +  +     FST D DND C   C  +++G        
Sbjct: 404 QLYRLSVVGYSGSAGRQSSLVLQNTS-----FSTLDSDNDHCLCKCAQVMSG-------- 450

Query: 327 LHNKTGWWFNECGLANLNGIHHFS--GKLLATGIQW 360
                GWWF+ CGL+NLNG+++ +   K    GI+W
Sbjct: 451 -----GWWFDACGLSNLNGVYYHAPDNKYKMDGIRW 481


>gi|223029463 fibrinogen C domain containing 1 [Homo sapiens]
          Length = 461

 Score =  121 bits (304), Expect = 9e-28
 Identities = 92/309 (29%), Positives = 145/309 (46%), Gaps = 41/309 (13%)

Query: 88  VSYTRSTKKLLRNMMDEQQASLDYLSNQVNELMNRVLL---LTTEVFRKQLDPFPHRPVQ 144
           +S  +S +  L  ++ E Q  + +L N V+++++ +     L     +  L   P R  +
Sbjct: 172 LSALQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTR 231

Query: 145 SHGL-------DCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQK 197
             G        DC D+  +     +   G+Y + P      F+V CDM   GGG TV Q+
Sbjct: 232 PRGCATGSRPRDCLDVLLS----GQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQR 287

Query: 198 RIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYA 257
           R DG ++F R W  Y DGFG L GE WLGLK+I  +  Q   ++ L+V LE  ++  AYA
Sbjct: 288 REDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQ--AAYELHVDLEDFENGTAYA 345

Query: 258 SYDNFW-----LEDETRFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPFSTSDVDNDGCRP 312
            Y +F      ++ E   + + +  YSG AGD+          + M F+T D D+D    
Sbjct: 346 RYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLL------KHSGMRFTTKDRDSD---- 395

Query: 313 ACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIH-HFSGKLLATGIQWGTWTKNNSPVK 371
                  S  +C+  + +  WW+  C  +NLNG +   +    A G++W +WT       
Sbjct: 396 ------HSENNCAAFY-RGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWT--GWQYS 446

Query: 372 IKSVSMKIR 380
           +K   MKIR
Sbjct: 447 LKFSEMKIR 455


>gi|223029461 fibrinogen C domain containing 1 [Homo sapiens]
          Length = 461

 Score =  121 bits (304), Expect = 9e-28
 Identities = 92/309 (29%), Positives = 145/309 (46%), Gaps = 41/309 (13%)

Query: 88  VSYTRSTKKLLRNMMDEQQASLDYLSNQVNELMNRVLL---LTTEVFRKQLDPFPHRPVQ 144
           +S  +S +  L  ++ E Q  + +L N V+++++ +     L     +  L   P R  +
Sbjct: 172 LSALQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTR 231

Query: 145 SHGL-------DCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQK 197
             G        DC D+  +     +   G+Y + P      F+V CDM   GGG TV Q+
Sbjct: 232 PRGCATGSRPRDCLDVLLS----GQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQR 287

Query: 198 RIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYA 257
           R DG ++F R W  Y DGFG L GE WLGLK+I  +  Q   ++ L+V LE  ++  AYA
Sbjct: 288 REDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQ--AAYELHVDLEDFENGTAYA 345

Query: 258 SYDNFW-----LEDETRFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPFSTSDVDNDGCRP 312
            Y +F      ++ E   + + +  YSG AGD+          + M F+T D D+D    
Sbjct: 346 RYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLL------KHSGMRFTTKDRDSD---- 395

Query: 313 ACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIH-HFSGKLLATGIQWGTWTKNNSPVK 371
                  S  +C+  + +  WW+  C  +NLNG +   +    A G++W +WT       
Sbjct: 396 ------HSENNCAAFY-RGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWT--GWQYS 446

Query: 372 IKSVSMKIR 380
           +K   MKIR
Sbjct: 447 LKFSEMKIR 455


>gi|70906435 fibrinogen, beta chain preproprotein [Homo sapiens]
          Length = 491

 Score =  121 bits (304), Expect = 9e-28
 Identities = 98/337 (29%), Positives = 152/337 (45%), Gaps = 53/337 (15%)

Query: 75  EKHFMCRNLQNSIVSYTRSTKKLLRNMMDEQQASLDYLSNQVNELMNRVLLLTTEVFRKQ 134
           EKH +   +  ++ S   +  ++LR++++  ++ +  L + V+  M        E  R  
Sbjct: 177 EKHQLY--IDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQM--------EYCRTP 226

Query: 135 LDPFPHRPVQSHGLDCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGRTV 194
                + PV S G +C +I    G  ++    +Y+I P+ S  P+ V CDM+   GG TV
Sbjct: 227 CTVSCNIPVVS-GKECEEIIRKGGETSE----MYLIQPDSSVKPYRVYCDMNTENGGWTV 281

Query: 195 IQKRIDGIIDFQRLWCDYLDGFGD------------LLGEFWLGLKKIFYIVNQKNTSFM 242
           IQ R DG +DF R W  Y  GFG+            L GE+WLG  KI  +     T   
Sbjct: 282 IQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTE-- 339

Query: 243 LYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRG----LKKEDN---- 294
           L + +E        A Y  F +++E   +++ + +Y G AG+A       L  E+     
Sbjct: 340 LLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTI 399

Query: 295 QNAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKL- 353
            N M FST D DNDG      +     K CS   +  GWW+N C  AN NG +++ G+  
Sbjct: 400 HNGMFFSTYDRDNDG-----WLTSDPRKQCSK-EDGGGWWYNRCHAANPNGRYYWGGQYT 453

Query: 354 -------LATGIQWGTWTKNNSPVKIKSVSMKIRRMY 383
                     G+ W  W    S   ++ +SMKIR  +
Sbjct: 454 WDMAKHGTDDGVVWMNW--KGSWYSMRKMSMKIRPFF 488


>gi|157384973 tenascin R [Homo sapiens]
          Length = 1358

 Score =  119 bits (297), Expect = 6e-27
 Identities = 80/219 (36%), Positives = 105/219 (47%), Gaps = 25/219 (11%)

Query: 163  TPSGLYIIHPEGS-SYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLG 221
            T SG+Y I   G  S   +V CDM   GGG  V Q+R +G  DF R W DY  GFG++  
Sbjct: 1147 TLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVED 1206

Query: 222  EFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGN 281
            EFWLGL  I  I +Q    + L V +    +  A+ASYD F +ED    +K+ +G Y+G 
Sbjct: 1207 EFWLGLDNIHRITSQGR--YELRVDMRDGQEA-AFASYDRFSVEDSRNLYKLRIGSYNGT 1263

Query: 282  AGDAFRGLKKEDNQNAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLA 341
            AGD+             PFST D DND           +V +C+ +  K  WW+  C   
Sbjct: 1264 AGDSL------SYHQGRPFSTEDRDND----------VAVTNCA-MSYKGAWWYKNCHRT 1306

Query: 342  NLNGIHHFSGKLLATGIQWGTWTKNNSPVKIKSVSMKIR 380
            NLNG   +     + GI W  W        I  V MK+R
Sbjct: 1307 NLNG--KYGESRHSQGINWYHW--KGHEFSIPFVEMKMR 1341


>gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E
           preproprotein [Homo sapiens]
          Length = 866

 Score =  116 bits (291), Expect = 3e-26
 Identities = 89/258 (34%), Positives = 129/258 (50%), Gaps = 41/258 (15%)

Query: 141 RPVQSHGLDCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRID 200
           RPV+    DC D+  T  S T+  SG++ I   GSS  F V CD +   GG  +IQ+R+D
Sbjct: 627 RPVR----DCDDVLQTHPSGTQ--SGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMD 680

Query: 201 GIIDFQRLWCDYLDGFGDL----LGEFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAY 256
           G ++F R W DY  GFG L     GEFWLG     +++ Q+ +  +L V LE      AY
Sbjct: 681 GSLNFNRTWQDYKRGFGSLNDEGEGEFWLG-NDYLHLLTQRGS--VLRVELEDWAGNEAY 737

Query: 257 ASYDNFWLEDETRFFKMHLGRYSGNAGDA-FRGLKKE----DNQNAMPFSTSDVDNDGCR 311
           A Y +F +  E   + + +  Y G AGDA   G  +E     + N M FST D D D   
Sbjct: 738 AEY-HFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDAD--- 793

Query: 312 PACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKL---------LATGIQWGT 362
                  Q  ++C+ ++   GWW+N C  ANLNGI++  G           +  G+ W +
Sbjct: 794 -------QWEENCAEVYG-GGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVS 845

Query: 363 WTKNNSPVKIKSVSMKIR 380
           +    +   +++V MKIR
Sbjct: 846 F--RGADYSLRAVRMKIR 861


>gi|8051586 ficolin 2 isoform b precursor [Homo sapiens]
          Length = 275

 Score =  114 bits (285), Expect = 1e-25
 Identities = 76/205 (37%), Positives = 101/205 (49%), Gaps = 23/205 (11%)

Query: 178 PFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQK 237
           P  V+CDMD  GGG TV Q+R+DG +DF R W  Y  GFG  LGEFWLG   I  +  Q 
Sbjct: 90  PLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQG 149

Query: 238 NTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRY-SGNAGDAFRGLKKEDNQN 296
            +   L V L   +D   +A Y +F + DE   + + LG +  G+AGD+   L   +NQ+
Sbjct: 150 TSE--LRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDS---LTFHNNQS 204

Query: 297 AMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIH-HFSGKLLA 355
              FST D DND     C V  Q             WW+  C ++NLNG +   +    A
Sbjct: 205 ---FSTKDQDNDLNTGNCAVMFQG-----------AWWYKNCHVSNLNGRYLRGTHGSFA 250

Query: 356 TGIQWGTWTKNNSPVKIKSVSMKIR 380
            GI W +    N   K+    MK+R
Sbjct: 251 NGINWKSGKGYNYSYKVS--EMKVR 273


>gi|61744445 ficolin 2 isoform a precursor [Homo sapiens]
          Length = 313

 Score =  114 bits (285), Expect = 1e-25
 Identities = 76/205 (37%), Positives = 101/205 (49%), Gaps = 23/205 (11%)

Query: 178 PFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQK 237
           P  V+CDMD  GGG TV Q+R+DG +DF R W  Y  GFG  LGEFWLG   I  +  Q 
Sbjct: 128 PLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQG 187

Query: 238 NTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRY-SGNAGDAFRGLKKEDNQN 296
            +   L V L   +D   +A Y +F + DE   + + LG +  G+AGD+   L   +NQ+
Sbjct: 188 TSE--LRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDS---LTFHNNQS 242

Query: 297 AMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIH-HFSGKLLA 355
              FST D DND     C V  Q             WW+  C ++NLNG +   +    A
Sbjct: 243 ---FSTKDQDNDLNTGNCAVMFQG-----------AWWYKNCHVSNLNGRYLRGTHGSFA 288

Query: 356 TGIQWGTWTKNNSPVKIKSVSMKIR 380
            GI W +    N   K+    MK+R
Sbjct: 289 NGINWKSGKGYNYSYKVS--EMKVR 311


>gi|29893555 angiopoietin-like 6 [Homo sapiens]
          Length = 470

 Score =  112 bits (281), Expect = 4e-25
 Identities = 68/203 (33%), Positives = 99/203 (48%), Gaps = 24/203 (11%)

Query: 181 VMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTS 240
           V C+    GGG TVIQ+R DG ++F   W  Y  GFG   GE+WLGL+ ++ + ++ +  
Sbjct: 285 VWCEQQLEGGGWTVIQRRQDGSVNFFTTWQHYKAGFGRPDGEYWLGLEPVYQLTSRGDHE 344

Query: 241 FMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPF 300
             L V LE      A A YD F LE E+  +++ LG+Y G+AGD+          N  PF
Sbjct: 345 --LLVLLEDWGGRGARAHYDGFSLEPESDHYRLRLGQYHGDAGDSLSW------HNDKPF 396

Query: 301 STSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKLLA---TG 357
           ST D D D     C            L+ + GWW++ C  +NLNG+ H  G   +    G
Sbjct: 397 STVDRDRDSYSGNCA-----------LYQRGGWWYHACAHSNLNGVWHHGGHYRSRYQDG 445

Query: 358 IQWGTWTKNNSPVKIKSVSMKIR 380
           + W  +        ++  +M IR
Sbjct: 446 VYWAEF--RGGAYSLRKAAMLIR 466


>gi|23111005 microfibrillar-associated protein 4 [Homo sapiens]
          Length = 255

 Score =  112 bits (280), Expect = 6e-25
 Identities = 82/241 (34%), Positives = 110/241 (45%), Gaps = 32/241 (13%)

Query: 148 LDCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQR 207
           LDC DI     +      G+Y+I+P G S P  V CDM   GG  TV QKR +G + F R
Sbjct: 39  LDCDDIY----AQGYQSDGVYLIYPSGPSVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFR 94

Query: 208 LWCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLE-- 265
            W DY  GFG   GE+WLGL+ +  +  ++   + L V LE  ++  AYA Y +F +   
Sbjct: 95  GWNDYKLGFGRADGEYWLGLQNMHLLTLKQ--KYELRVDLEDFENNTAYAKYADFSISPN 152

Query: 266 ----DETRFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPFSTSDVDNDGCRPACLVNGQSV 321
               +E  +     G   G AGD+          +   FST D D D            V
Sbjct: 153 AVSAEEDGYTLFVAGFEDGGAGDSL------SYHSGQKFSTFDRDQD----------LFV 196

Query: 322 KSCSHLHNKTGWWFNECGLANLNGIHHFSGKL-LATGIQWGTWTKNNSPVKIKSVSMKIR 380
           ++C+ L +   +WF  C  ANLNG +     L  A GI W  W        +K   MKIR
Sbjct: 197 QNCAAL-SSGAFWFRSCHFANLNGFYLGGSHLSYANGINWAQW--KGFYYSLKRTEMKIR 253

Query: 381 R 381
           R
Sbjct: 254 R 254


>gi|8051584 ficolin 1 precursor [Homo sapiens]
          Length = 326

 Score =  110 bits (274), Expect = 3e-24
 Identities = 72/205 (35%), Positives = 97/205 (47%), Gaps = 23/205 (11%)

Query: 178 PFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQK 237
           P  V+CDMD  GGG TV Q+R+DG +DF R W  Y  GFG  LGEFWLG   I  +  Q 
Sbjct: 141 PLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQG 200

Query: 238 NTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRY-SGNAGDAFRGLKKEDNQN 296
           ++   L V L   +    +A Y +F + DE   +K+ LG +  G+AG++  G       N
Sbjct: 201 SSE--LRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTG------HN 252

Query: 297 AMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFS-GKLLA 355
              FST D DND     C    Q             WW+ +C  +NLNG++     +  A
Sbjct: 253 NNFFSTKDQDNDVSSSNCAEKFQG-----------AWWYADCHASNLNGLYLMGPHESYA 301

Query: 356 TGIQWGTWTKNNSPVKIKSVSMKIR 380
            GI W          K+    MK+R
Sbjct: 302 NGINWSAAKGYKYSYKVS--EMKVR 324


>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
          Length = 673

 Score =  108 bits (269), Expect = 1e-23
 Identities = 62/208 (29%), Positives = 99/208 (47%), Gaps = 22/208 (10%)

Query: 178 PFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQK 237
           P  V CDM+  GGG  V Q+R+DG  DF R W DY  GFG++ GEFWLG + +  +    
Sbjct: 484 PLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAG 543

Query: 238 NTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGLKKEDNQNA 297
           +  + + V L + D+ + +A YD+F ++    ++++HL  Y G AGD+          + 
Sbjct: 544 D--YSMRVDLRAGDEAV-FAQYDSFHVDSAAEYYRLHLEGYHGTAGDSM------SYHSG 594

Query: 298 MPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKLLATG 357
             FS  D D +    +C V+            +  WW+  C  ANLNG+  +   +   G
Sbjct: 595 SVFSARDRDPNSLLISCAVS-----------YRGAWWYRNCHYANLNGL--YGSTVDHQG 641

Query: 358 IQWGTWTKNNSPVKIKSVSMKIRRMYNP 385
           + W  W      V    + ++ R   +P
Sbjct: 642 VSWYHWKGFEFSVPFTEMKLRPRNFRSP 669


>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
          Length = 4242

 Score =  108 bits (269), Expect = 1e-23
 Identities = 62/208 (29%), Positives = 99/208 (47%), Gaps = 22/208 (10%)

Query: 178  PFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQK 237
            P  V CDM+  GGG  V Q+R+DG  DF R W DY  GFG++ GEFWLG + +  +    
Sbjct: 4053 PLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAG 4112

Query: 238  NTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGLKKEDNQNA 297
            +  + + V L + D+ + +A YD+F ++    ++++HL  Y G AGD+          + 
Sbjct: 4113 D--YSMRVDLRAGDEAV-FAQYDSFHVDSAAEYYRLHLEGYHGTAGDSM------SYHSG 4163

Query: 298  MPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKLLATG 357
              FS  D D +    +C V+            +  WW+  C  ANLNG+  +   +   G
Sbjct: 4164 SVFSARDRDPNSLLISCAVS-----------YRGAWWYRNCHYANLNGL--YGSTVDHQG 4210

Query: 358  IQWGTWTKNNSPVKIKSVSMKIRRMYNP 385
            + W  W      V    + ++ R   +P
Sbjct: 4211 VSWYHWKGFEFSVPFTEMKLRPRNFRSP 4238


>gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens]
          Length = 288

 Score =  102 bits (253), Expect = 8e-22
 Identities = 72/205 (35%), Positives = 98/205 (47%), Gaps = 28/205 (13%)

Query: 163 TPSGLY-IIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLG 221
           T SG Y +  PEG + P  V CDMD  GGG  V Q+R DG +DF R W  Y  GFG+   
Sbjct: 91  TLSGWYHLCLPEGRALP--VFCDMDTEGGGWLVFQRRQDGSVDFFRSWSSYRAGFGNQES 148

Query: 222 EFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYS-G 280
           EFWLG + +  +  Q N  + L V LE  +    +A Y  F L  E   +++ LG++S G
Sbjct: 149 EFWLGNENLHQLTLQGN--WELRVELEDFNGNRTFAHYATFRLLGEVDHYQLALGKFSEG 206

Query: 281 NAGDAFRGLKKEDNQNAMPFSTSDVDNDGCRPAC--LVNGQSVKSCSHLHNKTGWWFNEC 338
            AGD+          +  PF+T D D+D     C  +V+G              WW+  C
Sbjct: 207 TAGDSL------SLHSGRPFTTYDADHDSSNSNCAVIVHG-------------AWWYASC 247

Query: 339 GLANLNGIHHFS-GKLLATGIQWGT 362
             +NLNG +  S       GI W +
Sbjct: 248 YRSNLNGRYAVSEAAAHKYGIDWAS 272


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,745,800
Number of Sequences: 37866
Number of extensions: 656699
Number of successful extensions: 1770
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1641
Number of HSP's gapped (non-prelim): 56
length of query: 388
length of database: 18,247,518
effective HSP length: 104
effective length of query: 284
effective length of database: 14,309,454
effective search space: 4063884936
effective search space used: 4063884936
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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