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Search of human proteins with 112799849
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|112799849 tumor protein p53 binding protein, 2 isoform 1
[Homo sapiens]
(1134 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom... 2284 0.0
gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ... 2015 0.0
gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens] 951 0.0
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 281 3e-75
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 281 3e-75
gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 1... 89 2e-17
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 87 9e-17
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 87 9e-17
gi|14249672 protein phosphatase 1, regulatory (inhibitor) subuni... 82 3e-15
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 82 4e-15
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit... 82 4e-15
gi|20270347 ankyrin repeat domain 54 [Homo sapiens] 75 4e-13
gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo ... 75 5e-13
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 69 3e-11
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 69 3e-11
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 69 3e-11
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 69 3e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 68 4e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 68 6e-11
gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo ... 67 7e-11
gi|28605137 proteasome 26S non-ATPase subunit 10 isform 2 [Homo ... 67 7e-11
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] 67 1e-10
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 67 1e-10
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 67 1e-10
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 67 1e-10
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens] 67 1e-10
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 66 2e-10
gi|41350198 fetal globin inducing factor [Homo sapiens] 65 5e-10
gi|221139761 zinc finger protein 853 [Homo sapiens] 64 6e-10
gi|148746195 trichohyalin [Homo sapiens] 64 6e-10
>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
sapiens]
Length = 1134
Score = 2284 bits (5919), Expect = 0.0
Identities = 1134/1134 (100%), Positives = 1134/1134 (100%)
Query: 1 MRFGSKMMPMFLTVYLSNNEQHFTEVPVTPETICRDVVDLCKEPGESDCHLAEVWCGSER 60
MRFGSKMMPMFLTVYLSNNEQHFTEVPVTPETICRDVVDLCKEPGESDCHLAEVWCGSER
Sbjct: 1 MRFGSKMMPMFLTVYLSNNEQHFTEVPVTPETICRDVVDLCKEPGESDCHLAEVWCGSER 60
Query: 61 PVADNERMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRR 120
PVADNERMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRR
Sbjct: 61 PVADNERMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRR 120
Query: 121 KENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQE 180
KENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQE
Sbjct: 121 KENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQE 180
Query: 181 KLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSK 240
KLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSK
Sbjct: 181 KLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSK 240
Query: 241 VEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKR 300
VEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKR
Sbjct: 241 VEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKR 300
Query: 301 NSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSS 360
NSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSS
Sbjct: 301 NSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSS 360
Query: 361 TMPRMPSRPELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWS 420
TMPRMPSRPELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWS
Sbjct: 361 TMPRMPSRPELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWS 420
Query: 421 PSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGT 480
PSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGT
Sbjct: 421 PSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGT 480
Query: 481 LRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLS 540
LRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLS
Sbjct: 481 LRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLS 540
Query: 541 TVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTL 600
TVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTL
Sbjct: 541 TVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTL 600
Query: 601 LPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQ 660
LPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQ
Sbjct: 601 LPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQ 660
Query: 661 NQQQHPENIYSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQS 720
NQQQHPENIYSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQS
Sbjct: 661 NQQQHPENIYSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQS 720
Query: 721 DADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKS 780
DADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKS
Sbjct: 721 DADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKS 780
Query: 781 ASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEP 840
ASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEP
Sbjct: 781 ASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEP 840
Query: 841 EGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEI 900
EGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEI
Sbjct: 841 EGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEI 900
Query: 901 TGQVSLPPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSL 960
TGQVSLPPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSL
Sbjct: 901 TGQVSLPPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSL 960
Query: 961 PNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVES 1020
PNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVES
Sbjct: 961 PNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVES 1020
Query: 1021 GAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDD 1080
GAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDD
Sbjct: 1021 GAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDD 1080
Query: 1081 ELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA 1134
ELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA
Sbjct: 1081 ELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA 1134
>gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
sapiens]
Length = 1005
Score = 2015 bits (5220), Expect = 0.0
Identities = 1005/1005 (100%), Positives = 1005/1005 (100%)
Query: 130 MDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIA 189
MDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIA
Sbjct: 1 MDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIA 60
Query: 190 ENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE 249
ENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE
Sbjct: 61 ENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE 120
Query: 250 MLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDK 309
MLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDK
Sbjct: 121 MLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDK 180
Query: 310 RVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRP 369
RVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRP
Sbjct: 181 RVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRP 240
Query: 370 ELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPS 429
ELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPS
Sbjct: 241 ELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPS 300
Query: 430 QGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSED 489
QGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSED
Sbjct: 301 QGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSED 360
Query: 490 ILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTK 549
ILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTK
Sbjct: 361 ILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTK 420
Query: 550 PKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQT 609
PKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQT
Sbjct: 421 PKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQT 480
Query: 610 VAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENI 669
VAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENI
Sbjct: 481 VAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENI 540
Query: 670 YSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRK 729
YSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRK
Sbjct: 541 YSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRK 600
Query: 730 KLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSES 789
KLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSES
Sbjct: 601 KLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSES 660
Query: 790 PVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPN 849
PVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPN
Sbjct: 661 PVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPN 720
Query: 850 LQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPG 909
LQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPG
Sbjct: 721 LQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPG 780
Query: 910 KRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL 969
KRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL
Sbjct: 781 KRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL 840
Query: 970 HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 1029
HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY
Sbjct: 841 HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 900
Query: 1030 SDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDC 1089
SDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDC
Sbjct: 901 SDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDC 960
Query: 1090 MTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA 1134
MTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA
Sbjct: 961 MTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA 1005
>gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens]
Length = 1090
Score = 951 bits (2458), Expect = 0.0
Identities = 551/1154 (47%), Positives = 703/1154 (60%), Gaps = 90/1154 (7%)
Query: 7 MMPMFLTVYLSNNEQHFTEVPVTPETICRDVVDLCKEPGESDCHLAEVWCGSERPVADNE 66
MMPM LTV+LSNNEQ TEVP+TPET CRDVV+ CKEPGE CHLAEVW G+ERP+ +
Sbjct: 1 MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDH 60
Query: 67 RMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPR-SQDPSLKRNGVKVPGEYRRKENGV 125
M++ LQ++G +R EV+FFLRHE P + G R +Q+ +RN + VPGE +R ENGV
Sbjct: 61 MMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGE-KRTENGV 119
Query: 126 NSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRL 185
+PR++LTL+ELQ+MA+RQQQQIE QQQ+L KEQRL FLKQQ++RQQQ ++E EKL++L
Sbjct: 120 GNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKL 179
Query: 186 KEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELT 245
KE E QE KLKK+RA++G V+ ++ NG L EIE+ + +FQ+K++E+ A+ +V++L+
Sbjct: 180 KERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLS 239
Query: 246 RQLEMLKNGRIDSHHDNQS-----AVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKR 300
+QLE LK G+++ A EL RLY+ELQ+RN+LNQEQN+KLQQQ+E LNKR
Sbjct: 240 QQLEDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKR 299
Query: 301 NSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSS 360
N EVA+MDKR++ELR+RL+ KK L + + PQ S RVAAVGPYIQ
Sbjct: 300 NMEVAMMDKRISELRERLYGKKIQLNRVNGT------SSPQSPLSTSGRVAAVGPYIQVP 353
Query: 361 TMPRMPSRPELLVKPALPDG-SLVIQASEGPMKIQ---TLPNMRSGAASQTKGSKIHPVG 416
+ P +L P P S+ A+ G K P ++ ++S K + G
Sbjct: 354 SAGSFP----VLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVK--PVQVAG 407
Query: 417 PDWSPSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPP 476
DW + + QG+ S +AL + + + + + PP
Sbjct: 408 ADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG-------KQLPP 460
Query: 477 SFGTLRKNQSSEDILRDAQVANKNVAKVPPP---VPTKPKQINLPYFGQTNQPPSDIKPD 533
S+GT + + + + + +P P +P++ + LP G T QP
Sbjct: 461 SYGTY-PSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQP------- 512
Query: 534 GSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTP 593
GSSQQ+ Q+ V SP+ P G + SK E P A+RPF
Sbjct: 513 GSSQQIQ--------------QRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLA 558
Query: 594 QPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGK 653
P + PQTV +SSIYSMY QQ P KN+Q A SAL K+ +VYGK
Sbjct: 559 DKGSRP-QSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKS------VKAVYGK 611
Query: 654 PVIAAAQNQQQ-----HPENIYSNSQGKPGS----PEPETEPVSSVQENHENERIPRPLS 704
PV+ + H Q +P S EPE + ++ + E +PRPLS
Sbjct: 612 PVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLS 671
Query: 705 PTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTT 764
PTKL P + +P R QSDADLEALR+KL+NAPRPLKKRSSITEPEGP GPNIQKLLYQR
Sbjct: 672 PTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFN 731
Query: 765 IAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNAST 824
A P Y + + + V+ N + E+ + L E ++
Sbjct: 732 TLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDA 791
Query: 825 ENSDMPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGE 884
++++P+P P E P + E+ N V P P P E
Sbjct: 792 NDNELPSPEP----EELICPQTTHQTAEPAEDNNNNVATV--------PTTEQIPSPVAE 839
Query: 885 PEGPGEDSVSMRPPEITGQVSLPP----GKRTNLRKTGSERIAHGMRVKFNPLALLLDSS 940
PGE+ V PP S PP KRTNL+K SER HG+RV+FNPLALLLD+S
Sbjct: 840 APSPGEEQV---PPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDAS 896
Query: 941 LEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWT 1000
LEGEFDLVQRIIYEV+DPS PNDEGIT LHNAVCAGH IVKFL+ FGVNVNAADSDGWT
Sbjct: 897 LEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWT 956
Query: 1001 PLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKM 1060
PLHCAASCN+V +CK LVESGAA+FA T SD++TAADKCEEMEEGY QCSQFLYGVQEK+
Sbjct: 957 PLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKL 1016
Query: 1061 GIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLL 1120
G+MNKGV YALWDYE QN DEL EGD +TI+ R+DE E EWWWARL D+EGYVP+NLL
Sbjct: 1017 GVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLL 1076
Query: 1121 GLYPRIKPRQRSLA 1134
GLYPRIKPRQR+LA
Sbjct: 1077 GLYPRIKPRQRTLA 1090
>gi|215820635 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 281 bits (718), Expect = 3e-75
Identities = 237/810 (29%), Positives = 346/810 (42%), Gaps = 133/810 (16%)
Query: 414 PVGPDWSPSNADLFPSQGSASVPQ---STGNALDQVDDG-EVPLREKEKK--VRPFSMFD 467
P GP P + P S+S+P+ S G+ DG + P E + P+S
Sbjct: 56 PPGPQAGPPSRP--PRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLS 113
Query: 468 AVDQSNAP--------PSFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLP- 518
+ ++P ++G+L + S D ++ A P P P +Q P
Sbjct: 114 PKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPT 173
Query: 519 ---YFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLS 575
+ G+ P +G P G P+P P + G L
Sbjct: 174 PFDFLGRAGSPRGSPLAEGPQ----AFFPERGPSPRP----PATAYDAPASAFGSS-LLG 224
Query: 576 PGSKQESPPAAAV-------RPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKN 628
G +PP A RP D + +KP A+ ++ + +P
Sbjct: 225 SGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQ 284
Query: 629 FQQAVQSALTKTHTRGPHFSSVYGKP---VIAAAQNQQQHPENIYSNSQGKPG------- 678
+S+L G + P ++ + ++ Y S G G
Sbjct: 285 LLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPR 344
Query: 679 SPEPETE---PVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQ---------SDADLEA 726
S +P + P SS Q + P PLS ++ L N + S A
Sbjct: 345 SWQPVSRIPMPPSSPQPRGAPRQRPIPLS---MIFKLQNAFWEHGASRAMLPGSPLFTRA 401
Query: 727 LRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTAS 786
KL P+P + S +P+ P P Q Q T A P +P ++
Sbjct: 402 PPPKLQPQPQPQPQPQSQPQPQLPPQPQTQP---QTPTPA-------PQHPQQTWPPV-- 449
Query: 787 SESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAP-SPGLDYEPEGVPD 845
+E P + P +EPE E+ L+ L DV P P L E + VP+
Sbjct: 450 NEGPPK---PPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPE 506
Query: 846 NSPNLQNNPEEPNP--------EAPHVL--DVYLEEY----------------------- 872
+ E P P +AP V + ++Y
Sbjct: 507 LEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPEL 566
Query: 873 ------------PPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPGKRTNLRKTGSE 920
PP P PP P P P + S PPE + + R+ LRK GS
Sbjct: 567 SPITEGSEARAGPPAPAPPAPI-PPPAPSQSS----PPEQPQSMEM----RSVLRKAGSP 617
Query: 921 RIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEI 980
R A R + NPL LLLD++L GE ++VQ+ + E++DPS PN+EGITALHNA+C + I
Sbjct: 618 RKAR--RARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSI 675
Query: 981 VKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCE 1040
V FL+ G NVN+ DS GWTPLHCAASCN+ +C LV+ GAA+FA T SD TA +KC+
Sbjct: 676 VDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCD 735
Query: 1041 EMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDE 1100
EGY C+ +L V++ MG+MN G +YALWDY + DEL +EG+ +T++ R+ +E
Sbjct: 736 PYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEE 795
Query: 1101 IEWWWARLNDKEGYVPRNLLGLYPRIKPRQ 1130
+WWWA L+ +EGYVPRN GL+PR+KP++
Sbjct: 796 TDWWWAALHGQEGYVPRNYFGLFPRVKPQR 825
>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 281 bits (718), Expect = 3e-75
Identities = 237/810 (29%), Positives = 346/810 (42%), Gaps = 133/810 (16%)
Query: 414 PVGPDWSPSNADLFPSQGSASVPQ---STGNALDQVDDG-EVPLREKEKK--VRPFSMFD 467
P GP P + P S+S+P+ S G+ DG + P E + P+S
Sbjct: 56 PPGPQAGPPSRP--PRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLS 113
Query: 468 AVDQSNAP--------PSFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLP- 518
+ ++P ++G+L + S D ++ A P P P +Q P
Sbjct: 114 PKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPT 173
Query: 519 ---YFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLS 575
+ G+ P +G P G P+P P + G L
Sbjct: 174 PFDFLGRAGSPRGSPLAEGPQ----AFFPERGPSPRP----PATAYDAPASAFGSS-LLG 224
Query: 576 PGSKQESPPAAAV-------RPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKN 628
G +PP A RP D + +KP A+ ++ + +P
Sbjct: 225 SGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQ 284
Query: 629 FQQAVQSALTKTHTRGPHFSSVYGKP---VIAAAQNQQQHPENIYSNSQGKPG------- 678
+S+L G + P ++ + ++ Y S G G
Sbjct: 285 LLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPR 344
Query: 679 SPEPETE---PVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQ---------SDADLEA 726
S +P + P SS Q + P PLS ++ L N + S A
Sbjct: 345 SWQPVSRIPMPPSSPQPRGAPRQRPIPLS---MIFKLQNAFWEHGASRAMLPGSPLFTRA 401
Query: 727 LRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTAS 786
KL P+P + S +P+ P P Q Q T A P +P ++
Sbjct: 402 PPPKLQPQPQPQPQPQSQPQPQLPPQPQTQP---QTPTPA-------PQHPQQTWPPV-- 449
Query: 787 SESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAP-SPGLDYEPEGVPD 845
+E P + P +EPE E+ L+ L DV P P L E + VP+
Sbjct: 450 NEGPPK---PPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPE 506
Query: 846 NSPNLQNNPEEPNP--------EAPHVL--DVYLEEY----------------------- 872
+ E P P +AP V + ++Y
Sbjct: 507 LEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPEL 566
Query: 873 ------------PPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPGKRTNLRKTGSE 920
PP P PP P P P + S PPE + + R+ LRK GS
Sbjct: 567 SPITEGSEARAGPPAPAPPAPI-PPPAPSQSS----PPEQPQSMEM----RSVLRKAGSP 617
Query: 921 RIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEI 980
R A R + NPL LLLD++L GE ++VQ+ + E++DPS PN+EGITALHNA+C + I
Sbjct: 618 RKAR--RARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSI 675
Query: 981 VKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCE 1040
V FL+ G NVN+ DS GWTPLHCAASCN+ +C LV+ GAA+FA T SD TA +KC+
Sbjct: 676 VDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCD 735
Query: 1041 EMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDE 1100
EGY C+ +L V++ MG+MN G +YALWDY + DEL +EG+ +T++ R+ +E
Sbjct: 736 PYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEE 795
Query: 1101 IEWWWARLNDKEGYVPRNLLGLYPRIKPRQ 1130
+WWWA L+ +EGYVPRN GL+PR+KP++
Sbjct: 796 TDWWWAALHGQEGYVPRNYFGLFPRVKPQR 825
>gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 16B
[Homo sapiens]
Length = 567
Score = 89.0 bits (219), Expect = 2e-17
Identities = 50/132 (37%), Positives = 71/132 (53%), Gaps = 5/132 (3%)
Query: 910 KRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL 969
K R TG R +V F LL++SL + + V+ + P L N++G+TAL
Sbjct: 50 KHERKRSTGGRR----KKVSFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTAL 105
Query: 970 HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 1029
H EIVK L+ G NVNA D++ WTPLH AA+C ++ + K LV+ GA + A+
Sbjct: 106 HQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVN- 164
Query: 1030 SDMQTAADKCEE 1041
SD D CE+
Sbjct: 165 SDGNMPYDLCED 176
Score = 58.9 bits (141), Expect = 3e-08
Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Query: 964 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
+G T LH A G+ + L+ GV V+ D DGW PLH AA +Q+ + LV GA+
Sbjct: 228 QGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGAS 287
Query: 1024 VFAMTYSDMQTAADKCEEME 1043
+ A T D + D CEE E
Sbjct: 288 LSARTSMD-EMPIDLCEEEE 306
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 87.0 bits (214), Expect = 9e-17
Identities = 48/120 (40%), Positives = 73/120 (60%), Gaps = 3/120 (2%)
Query: 927 RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQ 986
+VKF+ A+ L + G+ D V ++++ D + N +G+TALH A + ++VKFLV+
Sbjct: 35 KVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVE 94
Query: 987 FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEE--MEE 1044
G N+N D++GW PLH AASC + + +FL+ GA V A+ S+ T D EE MEE
Sbjct: 95 NGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN-SEGDTPLDIAEEEAMEE 153
Score = 66.2 bits (160), Expect = 2e-10
Identities = 36/84 (42%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
G TALH A G+TE++K L+Q G +VN D DGWTPLH AA + C+ LV++
Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDN-LCD 257
Query: 1025 FAMTYSDMQTAADKCEEMEEGYTQ 1048
M QTA D +E GY +
Sbjct: 258 MEMVNKVGQTAFDVADEDILGYLE 281
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit 12A
isoform a [Homo sapiens]
Length = 1030
Score = 87.0 bits (214), Expect = 9e-17
Identities = 48/120 (40%), Positives = 73/120 (60%), Gaps = 3/120 (2%)
Query: 927 RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQ 986
+VKF+ A+ L + G+ D V ++++ D + N +G+TALH A + ++VKFLV+
Sbjct: 35 KVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVE 94
Query: 987 FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEE--MEE 1044
G N+N D++GW PLH AASC + + +FL+ GA V A+ S+ T D EE MEE
Sbjct: 95 NGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN-SEGDTPLDIAEEEAMEE 153
Score = 66.2 bits (160), Expect = 2e-10
Identities = 36/84 (42%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
G TALH A G+TE++K L+Q G +VN D DGWTPLH AA + C+ LV++
Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDN-LCD 257
Query: 1025 FAMTYSDMQTAADKCEEMEEGYTQ 1048
M QTA D +E GY +
Sbjct: 258 MEMVNKVGQTAFDVADEDILGYLE 281
>gi|14249672 protein phosphatase 1, regulatory (inhibitor) subunit 16A
[Homo sapiens]
Length = 528
Score = 82.0 bits (201), Expect = 3e-15
Identities = 43/135 (31%), Positives = 77/135 (57%), Gaps = 3/135 (2%)
Query: 909 GKRTNLRKTGSERIAHGM--RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGI 966
GK+ + E + G+ +V F P +LL+++ + + V++ + P L N++G+
Sbjct: 46 GKKGPGERPRKEAASQGLLKQVLFPPSVVLLEAAARNDLEEVRQFLGSGVSPDLANEDGL 105
Query: 967 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFA 1026
TALH E+V+ L++ G N+NA DS+ WTPLH AA+C ++ + + L+ SGA + A
Sbjct: 106 TALHQCCIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLA 165
Query: 1027 MTYSDMQTAADKCEE 1041
+ +D D C++
Sbjct: 166 VN-TDGNMPYDLCDD 179
Score = 56.2 bits (134), Expect = 2e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Query: 957 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 1016
D P D G T LH A G +E L++ +++A D DGW PLH AA V + +
Sbjct: 224 DLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVEL 283
Query: 1017 LVESGAAVFAMTYSDMQTAADKCEEME 1043
LV GA + A + D +T D C + E
Sbjct: 284 LVAHGADLNAKSLMD-ETPLDVCGDEE 309
>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit 12B
isoform b [Homo sapiens]
Length = 998
Score = 81.6 bits (200), Expect = 4e-15
Identities = 42/115 (36%), Positives = 69/115 (60%), Gaps = 1/115 (0%)
Query: 927 RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQ 986
RV+F A+ L + G+ D V++++ D + N +G+TALH A + ++VKFLV+
Sbjct: 53 RVRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVE 112
Query: 987 FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEE 1041
NVN D++GWTPLH AASC + + ++ + GA+V + S+ + +D EE
Sbjct: 113 NRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASV-GIVNSEGEVPSDLAEE 166
Score = 58.2 bits (139), Expect = 4e-08
Identities = 25/56 (44%), Positives = 34/56 (60%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVES 1020
G TALH A G++E+++ L+Q G +N D DGWTPLH AA + C L E+
Sbjct: 217 GATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEA 272
Score = 31.6 bits (70), Expect = 4.5
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 7/109 (6%)
Query: 754 NIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPES 813
N +K+LY+ T + E +K +S ++S E E ++ E EKE
Sbjct: 334 NKEKMLYEEETPKSQEM----EEENKESSSSSSEEE--EGEDEASESETEKEADKKPEAF 387
Query: 814 LSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAP 862
++ + + S+ +PAP+ + S L N PEEP E+P
Sbjct: 388 VNHSNSESKSSITEQIPAPAQNT-FSASSARRFSSGLFNKPEEPKDESP 435
>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit 12B
isoform a [Homo sapiens]
Length = 982
Score = 81.6 bits (200), Expect = 4e-15
Identities = 42/115 (36%), Positives = 69/115 (60%), Gaps = 1/115 (0%)
Query: 927 RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQ 986
RV+F A+ L + G+ D V++++ D + N +G+TALH A + ++VKFLV+
Sbjct: 53 RVRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVE 112
Query: 987 FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEE 1041
NVN D++GWTPLH AASC + + ++ + GA+V + S+ + +D EE
Sbjct: 113 NRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASV-GIVNSEGEVPSDLAEE 166
Score = 58.2 bits (139), Expect = 4e-08
Identities = 25/56 (44%), Positives = 34/56 (60%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVES 1020
G TALH A G++E+++ L+Q G +N D DGWTPLH AA + C L E+
Sbjct: 217 GATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEA 272
Score = 31.6 bits (70), Expect = 4.5
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 7/109 (6%)
Query: 754 NIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPES 813
N +K+LY+ T + E +K +S ++S E E ++ E EKE
Sbjct: 334 NKEKMLYEEETPKSQEM----EEENKESSSSSSEEE--EGEDEASESETEKEADKKPEAF 387
Query: 814 LSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAP 862
++ + + S+ +PAP+ + S L N PEEP E+P
Sbjct: 388 VNHSNSESKSSITEQIPAPAQNT-FSASSARRFSSGLFNKPEEPKDESP 435
>gi|20270347 ankyrin repeat domain 54 [Homo sapiens]
Length = 300
Score = 75.1 bits (183), Expect = 4e-13
Identities = 49/145 (33%), Positives = 76/145 (52%), Gaps = 10/145 (6%)
Query: 933 LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVN 992
L L DS+ + + VQ+++ + DP +D+G TALH A C G+ +IV+ L+ G + N
Sbjct: 111 LKRLRDSANANDVETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPN 170
Query: 993 AADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADKCEEMEEGYTQC 1049
D G TPLH AA N+V V L+ GA V A+ + + A K ++EG+ QC
Sbjct: 171 QRDGLGNTPLHLAACTNHVPVITTLLRGGARVDALDRAGRTPLHLAKSKLNILQEGHAQC 230
Query: 1050 SQFLYGVQEKMGIMNKGVIYALWDY 1074
E + + K +I+ L +Y
Sbjct: 231 -------LEAVRLEVKQIIHMLREY 248
>gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo
sapiens]
Length = 782
Score = 74.7 bits (182), Expect = 5e-13
Identities = 56/175 (32%), Positives = 81/175 (46%), Gaps = 22/175 (12%)
Query: 883 GEPEGPGEDSVSMRPPEITGQVSLPPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLE 942
G GPG + + R E + G R ER A V+F A L +
Sbjct: 6 GPAAGPGAAAAAAR--ERRREQLRQWGARAGAEPGPGERRAR--TVRFERAAEFLAACAG 61
Query: 943 GEFDLVQRIIYEVD-------DPSLP----------NDEGITALHNAVCAGHTEIVKFLV 985
G+ D + ++ D DP+ P N +GI+ALH A + E+V+FLV
Sbjct: 62 GDLDEARLMLRAADPGPGAELDPAAPPPARAVLDSTNADGISALHQACIDENLEVVRFLV 121
Query: 986 QFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCE 1040
+ G VN AD++GWTPLH AASC + + ++L+ GA + A+ SD D E
Sbjct: 122 EQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVN-SDGDLPLDLAE 175
Score = 57.8 bits (138), Expect = 6e-08
Identities = 28/77 (36%), Positives = 42/77 (54%), Gaps = 1/77 (1%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
G +ALH A G+ E+++ L+Q G + D DGWTPLH AA C+ L E G +
Sbjct: 227 GASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGM 286
Query: 1025 FAMTYSDMQTAADKCEE 1041
++T++ Q D +E
Sbjct: 287 DSLTHAG-QRPCDLADE 302
Score = 42.7 bits (99), Expect = 0.002
Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 11/101 (10%)
Query: 907 PPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGI 966
PP R L T ++ I+ L + ++ ++V+ ++ + + ++EG
Sbjct: 87 PPPARAVLDSTNADGIS-----------ALHQACIDENLEVVRFLVEQGATVNQADNEGW 135
Query: 967 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAAS 1007
T LH A G+ +I ++L+ G N+ A +SDG PL A S
Sbjct: 136 TPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAES 176
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 68.9 bits (167), Expect = 3e-11
Identities = 38/93 (40%), Positives = 56/93 (60%)
Query: 931 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 990
N L L +S EG ++V ++ + +G TALH A AG E+VK LV G N
Sbjct: 73 NGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGAN 132
Query: 991 VNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
VNA +G+TPL+ AA N+++V KFL+++GA+
Sbjct: 133 VNAQSQNGFTPLYMAAQENHLEVVKFLLDNGAS 165
Score = 60.5 bits (145), Expect = 9e-09
Identities = 38/126 (30%), Positives = 61/126 (48%), Gaps = 9/126 (7%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G ++V ++++ P+ N G TALH A +G E+V++LVQ G V A D TPL
Sbjct: 444 GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPL 503
Query: 1003 HCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADKCEEMEEGYTQCSQFLYGVQEK 1059
H +A + + L++ GA+ A T Y+ + +A EG+ + FL
Sbjct: 504 HISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSA------REGHEDVAAFLLDHGAS 557
Query: 1060 MGIMNK 1065
+ I K
Sbjct: 558 LSITTK 563
Score = 55.1 bits (131), Expect = 4e-07
Identities = 24/81 (29%), Positives = 44/81 (54%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G+ D+VQ+++ + P+ G T LH + GH ++ FL+ G +++ G+TPL
Sbjct: 510 GKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPL 569
Query: 1003 HCAASCNNVQVCKFLVESGAA 1023
H AA ++V L++ A+
Sbjct: 570 HVAAKYGKLEVANLLLQKSAS 590
Score = 54.7 bits (130), Expect = 5e-07
Identities = 40/121 (33%), Positives = 57/121 (47%), Gaps = 5/121 (4%)
Query: 908 PGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGIT 967
P K+ RK +R + K + A L ++ G + I D ++ N G+
Sbjct: 22 PEKKRKHRKRSRDR-----KKKSDANASYLRAARAGHLEKALDYIKNGVDINICNQNGLN 76
Query: 968 ALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAM 1027
ALH A GH E+V L+Q NV+AA G T LH A+ +V K LV +GA V A
Sbjct: 77 ALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQ 136
Query: 1028 T 1028
+
Sbjct: 137 S 137
Score = 54.7 bits (130), Expect = 5e-07
Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 3/100 (3%)
Query: 942 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 1001
EG D+V ++ + +L N G+T LH A + + LV G +V+A G+TP
Sbjct: 674 EGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTP 733
Query: 1002 LHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 1038
LH N+++ FL++ A V A T Y+ + AA +
Sbjct: 734 LHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQ 773
Score = 53.9 bits (128), Expect = 8e-07
Identities = 29/87 (33%), Positives = 45/87 (51%)
Query: 942 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 1001
+ + D+ ++ D + +GI ++H A GH ++V L+ NVN ++ G TP
Sbjct: 641 KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTP 700
Query: 1002 LHCAASCNNVQVCKFLVESGAAVFAMT 1028
LH AA + V V + LV GA V A T
Sbjct: 701 LHLAAQEDRVNVAEVLVNQGAHVDAQT 727
Score = 53.1 bits (126), Expect = 1e-06
Identities = 29/78 (37%), Positives = 47/78 (60%), Gaps = 3/78 (3%)
Query: 955 VDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVC 1014
VDD + ++ +TALH A GH ++ K L+ N NA +G+TPLH A N ++V
Sbjct: 360 VDDVT---NDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVM 416
Query: 1015 KFLVESGAAVFAMTYSDM 1032
+ L++ GA++ A+T S +
Sbjct: 417 ELLLKHGASIQAVTESGL 434
Score = 52.8 bits (125), Expect = 2e-06
Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 3/123 (2%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G+ ++ ++ + P G+T LH A + ++ L+ G + +AA +G+TPL
Sbjct: 576 GKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPL 635
Query: 1003 HCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGI 1062
H AA N + + L+E GA A+T Q A +EG+ L G + +
Sbjct: 636 HIAAKKNQMDIATTLLEYGADANAVT---RQGIASVHLAAQEGHVDMVSLLLGRNANVNL 692
Query: 1063 MNK 1065
NK
Sbjct: 693 SNK 695
Score = 51.6 bits (122), Expect = 4e-06
Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 6/112 (5%)
Query: 930 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 989
+ PL L S+ EG D+ ++ S+ +G T LH A G E+ L+Q
Sbjct: 533 YTPLHL---SAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSA 589
Query: 990 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 1038
+ +AA G TPLH AA +N +V L++ GA+ A Y+ + AA K
Sbjct: 590 SPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKK 641
Score = 48.9 bits (115), Expect = 3e-05
Identities = 24/63 (38%), Positives = 35/63 (55%)
Query: 966 ITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVF 1025
IT LH A G+ +VK L+ G ++A DG TPLHC A + QV + L++ A +
Sbjct: 269 ITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPIL 328
Query: 1026 AMT 1028
+ T
Sbjct: 329 SKT 331
Score = 48.5 bits (114), Expect = 4e-05
Identities = 25/69 (36%), Positives = 35/69 (50%)
Query: 963 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ G+T +H A GH IV L+ G + N + G T LH AA +V ++LV+ GA
Sbjct: 431 ESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGA 490
Query: 1023 AVFAMTYSD 1031
V A D
Sbjct: 491 QVEAKAKDD 499
Score = 48.1 bits (113), Expect = 5e-05
Identities = 26/82 (31%), Positives = 45/82 (54%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+SL G+ ++V+ ++ + + + G T L+ A H E+VKFL+ G + + A DG
Sbjct: 114 ASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDG 173
Query: 999 WTPLHCAASCNNVQVCKFLVES 1020
+TPL A + QV L+E+
Sbjct: 174 FTPLAVALQQGHDQVVSLLLEN 195
Score = 45.1 bits (105), Expect = 4e-04
Identities = 23/64 (35%), Positives = 35/64 (54%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
G T LH G+ +IV FL+Q VNA +G+TPLH AA + + L+++ A+
Sbjct: 730 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASP 789
Query: 1025 FAMT 1028
+T
Sbjct: 790 NELT 793
Score = 41.6 bits (96), Expect = 0.004
Identities = 20/81 (24%), Positives = 41/81 (50%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G + + + ++ + +P+ G T LH A ++++ L++ G ++ A G TP+
Sbjct: 378 GHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPI 437
Query: 1003 HCAASCNNVQVCKFLVESGAA 1023
H AA +V + L+ GA+
Sbjct: 438 HVAAFMGHVNIVSQLMHHGAS 458
Score = 40.4 bits (93), Expect = 0.010
Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 7/95 (7%)
Query: 930 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 989
F PLA+ L D V ++ E D + ALH A T+ L+Q
Sbjct: 174 FTPLAVALQQG----HDQVVSLLLENDTKGKVR---LPALHIAARKDDTKAAALLLQNDN 226
Query: 990 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
N + G+TPLH AA N+ V L+ AAV
Sbjct: 227 NADVESKSGFTPLHIAAHYGNINVATLLLNRAAAV 261
Score = 40.4 bits (93), Expect = 0.010
Identities = 21/58 (36%), Positives = 31/58 (53%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
G++ LH A H V+ L+Q V V+ +D T LH AA C + +V K L++ A
Sbjct: 334 GLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKA 391
Score = 37.0 bits (84), Expect = 0.11
Identities = 24/105 (22%), Positives = 50/105 (47%), Gaps = 1/105 (0%)
Query: 931 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 990
N + L +S G ++V+ ++ +G+T LH +GH ++V+ L+
Sbjct: 267 NDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAP 326
Query: 991 VNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTA 1035
+ + +G +PLH A +++ + L++ V +T +D TA
Sbjct: 327 ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVT-NDYLTA 370
Score = 36.6 bits (83), Expect = 0.14
Identities = 20/73 (27%), Positives = 34/73 (46%)
Query: 956 DDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCK 1015
++ + + G T LH A G+ + L+ V+ + TPLH A+ N + K
Sbjct: 226 NNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVK 285
Query: 1016 FLVESGAAVFAMT 1028
L++ GA + A T
Sbjct: 286 LLLDRGAKIDAKT 298
Score = 31.2 bits (69), Expect = 5.8
Identities = 19/71 (26%), Positives = 28/71 (39%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G +V ++ + G T LH A GHT I+ L+Q + N +G T L
Sbjct: 741 GNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTAL 800
Query: 1003 HCAASCNNVQV 1013
A + V
Sbjct: 801 GIARRLGYISV 811
>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
Length = 1863
Score = 68.6 bits (166), Expect = 3e-11
Identities = 38/92 (41%), Positives = 54/92 (58%)
Query: 931 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 990
N L L ++ EG LVQ ++ +G TALH A AG E+VK LV+ G N
Sbjct: 42 NGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGAN 101
Query: 991 VNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+NA +G+TPL+ AA N++ V K+L+E+GA
Sbjct: 102 INAQSQNGFTPLYMAAQENHIDVVKYLLENGA 133
Score = 57.0 bits (136), Expect = 1e-07
Identities = 30/64 (46%), Positives = 39/64 (60%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
GIT LH A G+T +VK L+ G ++A DG TPLHCAA + QV + L+E GA +
Sbjct: 245 GITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL 304
Query: 1025 FAMT 1028
A T
Sbjct: 305 LART 308
Score = 55.1 bits (131), Expect = 4e-07
Identities = 31/78 (39%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
Query: 955 VDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVC 1014
VDD +L + +TALH A GH + K L+ N NA +G+TPLH A N ++V
Sbjct: 337 VDDVTL---DYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVM 393
Query: 1015 KFLVESGAAVFAMTYSDM 1032
+ LV+ GA++ A+T S +
Sbjct: 394 ELLVKYGASIQAITESGL 411
Score = 54.7 bits (130), Expect = 5e-07
Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 920 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 979
+ +AH N L S+ EG+ D+ ++ SL +G T LH A G +
Sbjct: 497 QHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLD 556
Query: 980 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAA 1036
+ K L+Q ++A +G TPLH AA +N +V L+E GA+ A Y+ + AA
Sbjct: 557 VAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAA 616
Query: 1037 DK 1038
K
Sbjct: 617 KK 618
Score = 48.5 bits (114), Expect = 4e-05
Identities = 25/82 (30%), Positives = 46/82 (56%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+SL G+ ++V+ ++ E + + + G T L+ A H ++VK+L++ G N + A DG
Sbjct: 83 ASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDG 142
Query: 999 WTPLHCAASCNNVQVCKFLVES 1020
+TPL A + Q L+E+
Sbjct: 143 FTPLAVALQQGHNQAVAILLEN 164
Score = 48.1 bits (113), Expect = 5e-05
Identities = 26/57 (45%), Positives = 36/57 (63%)
Query: 967 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
T LH A G TEIV+ L+Q + +AA ++G+TPLH +A V V L+E+GAA
Sbjct: 478 TPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAA 534
Score = 48.1 bits (113), Expect = 5e-05
Identities = 24/81 (29%), Positives = 41/81 (50%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G+ ++VQ ++ + P G T LH + G ++ L++ G + A G+TPL
Sbjct: 487 GKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPL 546
Query: 1003 HCAASCNNVQVCKFLVESGAA 1023
H AA ++ V K L++ AA
Sbjct: 547 HVAAKYGSLDVAKLLLQRRAA 567
Score = 47.4 bits (111), Expect = 8e-05
Identities = 28/98 (28%), Positives = 52/98 (53%)
Query: 931 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 990
N + L +S G ++V+ ++ +G+T LH A +GH ++V+ L++ G
Sbjct: 244 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 303
Query: 991 VNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 1028
+ A +G +PLH AA ++V+ K L++ A V +T
Sbjct: 304 LLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVT 341
Score = 47.0 bits (110), Expect = 1e-04
Identities = 27/86 (31%), Positives = 44/86 (51%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G ++V ++ P + N G TALH A AG E+V+ L++ G V+A + TPL
Sbjct: 421 GHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPL 480
Query: 1003 HCAASCNNVQVCKFLVESGAAVFAMT 1028
H A+ ++ + L++ A A T
Sbjct: 481 HIASRLGKTEIVQLLLQHMAHPDAAT 506
Score = 47.0 bits (110), Expect = 1e-04
Identities = 23/66 (34%), Positives = 36/66 (54%)
Query: 957 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 1016
+ ++ +G+T LH A GHT++V L+ G N++ + G T LH AA + V V
Sbjct: 633 ETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADI 692
Query: 1017 LVESGA 1022
L + GA
Sbjct: 693 LTKHGA 698
Score = 46.6 bits (109), Expect = 1e-04
Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 3/103 (2%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+S EG D+V ++ + + + G+T+LH A + L + G + +A G
Sbjct: 648 ASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLG 707
Query: 999 WTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 1038
+TPL A NV++ FL++ GA V A T Y+ + AA +
Sbjct: 708 YTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQ 750
Score = 45.4 bits (106), Expect = 3e-04
Identities = 25/64 (39%), Positives = 36/64 (56%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
G T L A G+ ++V FL++ G NVNA +G+TPLH AA + + L++ GA
Sbjct: 707 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKP 766
Query: 1025 FAMT 1028
A T
Sbjct: 767 NATT 770
Score = 45.1 bits (105), Expect = 4e-04
Identities = 24/64 (37%), Positives = 35/64 (54%)
Query: 963 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ G+T +H A GH IV L+Q G + + + G T LH AA V+V + L+ +GA
Sbjct: 408 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 467
Query: 1023 AVFA 1026
V A
Sbjct: 468 LVDA 471
Score = 45.1 bits (105), Expect = 4e-04
Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 5/108 (4%)
Query: 923 AHGMRVK--FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEI 980
AH + K F PL + ++ G D+ + ++ G+T LH A + ++
Sbjct: 534 AHSLATKKGFTPLHV---AAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKV 590
Query: 981 VKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 1028
L++ G + +A +G+TPLH AA N +Q+ L+ GA +T
Sbjct: 591 ALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVT 638
Score = 43.9 bits (102), Expect = 9e-04
Identities = 20/81 (24%), Positives = 44/81 (54%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G + + + ++ + +P+ G T LH A ++++ LV++G ++ A G TP+
Sbjct: 355 GHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPI 414
Query: 1003 HCAASCNNVQVCKFLVESGAA 1023
H AA ++ + L+++GA+
Sbjct: 415 HVAAFMGHLNIVLLLLQNGAS 435
Score = 42.0 bits (97), Expect = 0.003
Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 946 DLVQRIIYEVDDPSLPNDE-GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHC 1004
D V ++ E P L + G++ LH A H E VK L+Q V+ D T LH
Sbjct: 291 DQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHV 350
Query: 1005 AASCNNVQVCKFLVESGA 1022
AA C + +V K L++ A
Sbjct: 351 AAHCGHYRVTKLLLDKRA 368
Score = 40.8 bits (94), Expect = 0.007
Identities = 21/66 (31%), Positives = 32/66 (48%)
Query: 963 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ G T LH A G+ + L+ G V+ +G TPLH A+ N + K L++ G
Sbjct: 210 ESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGG 269
Query: 1023 AVFAMT 1028
+ A T
Sbjct: 270 QIDAKT 275
Score = 40.8 bits (94), Expect = 0.007
Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
Query: 914 LRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAV 973
L K G+++ AH ++ + PL + G +V ++ + + + G T LH A
Sbjct: 693 LTKHGADQDAH-TKLGYTPLIVACHY---GNVKMVNFLLKQGANVNAKTKNGYTPLHQAA 748
Query: 974 CAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 1013
GHT I+ L+Q G NA ++G T L A + V
Sbjct: 749 QQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISV 788
Score = 39.3 bits (90), Expect = 0.021
Identities = 21/75 (28%), Positives = 31/75 (41%)
Query: 958 PSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 1017
P G T LH A +I L+ +G N G TPLH A+ + + L
Sbjct: 601 PHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLL 660
Query: 1018 VESGAAVFAMTYSDM 1032
++ GA + T S +
Sbjct: 661 LDKGANIHMSTKSGL 675
Score = 38.1 bits (87), Expect = 0.048
Identities = 34/132 (25%), Positives = 49/132 (37%), Gaps = 40/132 (30%)
Query: 930 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFL----- 984
F PL + ++ E D+V+ ++ + S ++G T L A+ GH + V L
Sbjct: 110 FTPLYM---AAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDT 166
Query: 985 --------------------------------VQFGVNVNAADSDGWTPLHCAASCNNVQ 1012
VQ + VN G+TPLH AA NV
Sbjct: 167 KGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVN 226
Query: 1013 VCKFLVESGAAV 1024
V L+ GAAV
Sbjct: 227 VATLLLNRGAAV 238
>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
Length = 1872
Score = 68.6 bits (166), Expect = 3e-11
Identities = 38/92 (41%), Positives = 54/92 (58%)
Query: 931 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 990
N L L ++ EG LVQ ++ +G TALH A AG E+VK LV+ G N
Sbjct: 63 NGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGAN 122
Query: 991 VNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+NA +G+TPL+ AA N++ V K+L+E+GA
Sbjct: 123 INAQSQNGFTPLYMAAQENHIDVVKYLLENGA 154
Score = 57.0 bits (136), Expect = 1e-07
Identities = 30/64 (46%), Positives = 39/64 (60%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
GIT LH A G+T +VK L+ G ++A DG TPLHCAA + QV + L+E GA +
Sbjct: 266 GITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL 325
Query: 1025 FAMT 1028
A T
Sbjct: 326 LART 329
Score = 55.1 bits (131), Expect = 4e-07
Identities = 31/78 (39%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
Query: 955 VDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVC 1014
VDD +L + +TALH A GH + K L+ N NA +G+TPLH A N ++V
Sbjct: 358 VDDVTL---DYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVM 414
Query: 1015 KFLVESGAAVFAMTYSDM 1032
+ LV+ GA++ A+T S +
Sbjct: 415 ELLVKYGASIQAITESGL 432
Score = 54.7 bits (130), Expect = 5e-07
Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 920 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 979
+ +AH N L S+ EG+ D+ ++ SL +G T LH A G +
Sbjct: 518 QHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLD 577
Query: 980 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAA 1036
+ K L+Q ++A +G TPLH AA +N +V L+E GA+ A Y+ + AA
Sbjct: 578 VAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAA 637
Query: 1037 DK 1038
K
Sbjct: 638 KK 639
Score = 48.5 bits (114), Expect = 4e-05
Identities = 25/82 (30%), Positives = 46/82 (56%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+SL G+ ++V+ ++ E + + + G T L+ A H ++VK+L++ G N + A DG
Sbjct: 104 ASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDG 163
Query: 999 WTPLHCAASCNNVQVCKFLVES 1020
+TPL A + Q L+E+
Sbjct: 164 FTPLAVALQQGHNQAVAILLEN 185
Score = 48.1 bits (113), Expect = 5e-05
Identities = 26/57 (45%), Positives = 36/57 (63%)
Query: 967 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
T LH A G TEIV+ L+Q + +AA ++G+TPLH +A V V L+E+GAA
Sbjct: 499 TPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAA 555
Score = 48.1 bits (113), Expect = 5e-05
Identities = 24/81 (29%), Positives = 41/81 (50%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G+ ++VQ ++ + P G T LH + G ++ L++ G + A G+TPL
Sbjct: 508 GKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPL 567
Query: 1003 HCAASCNNVQVCKFLVESGAA 1023
H AA ++ V K L++ AA
Sbjct: 568 HVAAKYGSLDVAKLLLQRRAA 588
Score = 47.4 bits (111), Expect = 8e-05
Identities = 28/98 (28%), Positives = 52/98 (53%)
Query: 931 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 990
N + L +S G ++V+ ++ +G+T LH A +GH ++V+ L++ G
Sbjct: 265 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 324
Query: 991 VNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 1028
+ A +G +PLH AA ++V+ K L++ A V +T
Sbjct: 325 LLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVT 362
Score = 47.0 bits (110), Expect = 1e-04
Identities = 27/86 (31%), Positives = 44/86 (51%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G ++V ++ P + N G TALH A AG E+V+ L++ G V+A + TPL
Sbjct: 442 GHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPL 501
Query: 1003 HCAASCNNVQVCKFLVESGAAVFAMT 1028
H A+ ++ + L++ A A T
Sbjct: 502 HIASRLGKTEIVQLLLQHMAHPDAAT 527
Score = 47.0 bits (110), Expect = 1e-04
Identities = 23/66 (34%), Positives = 36/66 (54%)
Query: 957 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 1016
+ ++ +G+T LH A GHT++V L+ G N++ + G T LH AA + V V
Sbjct: 654 ETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADI 713
Query: 1017 LVESGA 1022
L + GA
Sbjct: 714 LTKHGA 719
Score = 46.6 bits (109), Expect = 1e-04
Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 3/103 (2%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+S EG D+V ++ + + + G+T+LH A + L + G + +A G
Sbjct: 669 ASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLG 728
Query: 999 WTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 1038
+TPL A NV++ FL++ GA V A T Y+ + AA +
Sbjct: 729 YTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQ 771
Score = 45.4 bits (106), Expect = 3e-04
Identities = 25/64 (39%), Positives = 36/64 (56%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
G T L A G+ ++V FL++ G NVNA +G+TPLH AA + + L++ GA
Sbjct: 728 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKP 787
Query: 1025 FAMT 1028
A T
Sbjct: 788 NATT 791
Score = 45.1 bits (105), Expect = 4e-04
Identities = 24/64 (37%), Positives = 35/64 (54%)
Query: 963 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ G+T +H A GH IV L+Q G + + + G T LH AA V+V + L+ +GA
Sbjct: 429 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 488
Query: 1023 AVFA 1026
V A
Sbjct: 489 LVDA 492
Score = 45.1 bits (105), Expect = 4e-04
Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 5/108 (4%)
Query: 923 AHGMRVK--FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEI 980
AH + K F PL + ++ G D+ + ++ G+T LH A + ++
Sbjct: 555 AHSLATKKGFTPLHV---AAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKV 611
Query: 981 VKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 1028
L++ G + +A +G+TPLH AA N +Q+ L+ GA +T
Sbjct: 612 ALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVT 659
Score = 43.9 bits (102), Expect = 9e-04
Identities = 20/81 (24%), Positives = 44/81 (54%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G + + + ++ + +P+ G T LH A ++++ LV++G ++ A G TP+
Sbjct: 376 GHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPI 435
Query: 1003 HCAASCNNVQVCKFLVESGAA 1023
H AA ++ + L+++GA+
Sbjct: 436 HVAAFMGHLNIVLLLLQNGAS 456
Score = 42.0 bits (97), Expect = 0.003
Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 946 DLVQRIIYEVDDPSLPNDE-GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHC 1004
D V ++ E P L + G++ LH A H E VK L+Q V+ D T LH
Sbjct: 312 DQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHV 371
Query: 1005 AASCNNVQVCKFLVESGA 1022
AA C + +V K L++ A
Sbjct: 372 AAHCGHYRVTKLLLDKRA 389
Score = 40.8 bits (94), Expect = 0.007
Identities = 21/66 (31%), Positives = 32/66 (48%)
Query: 963 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ G T LH A G+ + L+ G V+ +G TPLH A+ N + K L++ G
Sbjct: 231 ESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGG 290
Query: 1023 AVFAMT 1028
+ A T
Sbjct: 291 QIDAKT 296
Score = 40.8 bits (94), Expect = 0.007
Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
Query: 914 LRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAV 973
L K G+++ AH ++ + PL + G +V ++ + + + G T LH A
Sbjct: 714 LTKHGADQDAH-TKLGYTPLIVACHY---GNVKMVNFLLKQGANVNAKTKNGYTPLHQAA 769
Query: 974 CAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 1013
GHT I+ L+Q G NA ++G T L A + V
Sbjct: 770 QQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISV 809
Score = 39.3 bits (90), Expect = 0.021
Identities = 21/75 (28%), Positives = 31/75 (41%)
Query: 958 PSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 1017
P G T LH A +I L+ +G N G TPLH A+ + + L
Sbjct: 622 PHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLL 681
Query: 1018 VESGAAVFAMTYSDM 1032
++ GA + T S +
Sbjct: 682 LDKGANIHMSTKSGL 696
Score = 38.1 bits (87), Expect = 0.048
Identities = 34/132 (25%), Positives = 49/132 (37%), Gaps = 40/132 (30%)
Query: 930 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFL----- 984
F PL + ++ E D+V+ ++ + S ++G T L A+ GH + V L
Sbjct: 131 FTPLYM---AAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDT 187
Query: 985 --------------------------------VQFGVNVNAADSDGWTPLHCAASCNNVQ 1012
VQ + VN G+TPLH AA NV
Sbjct: 188 KGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVN 247
Query: 1013 VCKFLVESGAAV 1024
V L+ GAAV
Sbjct: 248 VATLLLNRGAAV 259
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 68.6 bits (166), Expect = 3e-11
Identities = 38/92 (41%), Positives = 54/92 (58%)
Query: 931 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 990
N L L ++ EG LVQ ++ +G TALH A AG E+VK LV+ G N
Sbjct: 63 NGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGAN 122
Query: 991 VNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+NA +G+TPL+ AA N++ V K+L+E+GA
Sbjct: 123 INAQSQNGFTPLYMAAQENHIDVVKYLLENGA 154
Score = 57.0 bits (136), Expect = 1e-07
Identities = 30/64 (46%), Positives = 39/64 (60%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
GIT LH A G+T +VK L+ G ++A DG TPLHCAA + QV + L+E GA +
Sbjct: 266 GITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL 325
Query: 1025 FAMT 1028
A T
Sbjct: 326 LART 329
Score = 55.1 bits (131), Expect = 4e-07
Identities = 31/78 (39%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
Query: 955 VDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVC 1014
VDD +L + +TALH A GH + K L+ N NA +G+TPLH A N ++V
Sbjct: 358 VDDVTL---DYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVM 414
Query: 1015 KFLVESGAAVFAMTYSDM 1032
+ LV+ GA++ A+T S +
Sbjct: 415 ELLVKYGASIQAITESGL 432
Score = 54.7 bits (130), Expect = 5e-07
Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 920 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 979
+ +AH N L S+ EG+ D+ ++ SL +G T LH A G +
Sbjct: 518 QHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLD 577
Query: 980 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAA 1036
+ K L+Q ++A +G TPLH AA +N +V L+E GA+ A Y+ + AA
Sbjct: 578 VAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAA 637
Query: 1037 DK 1038
K
Sbjct: 638 KK 639
Score = 48.5 bits (114), Expect = 4e-05
Identities = 25/82 (30%), Positives = 46/82 (56%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+SL G+ ++V+ ++ E + + + G T L+ A H ++VK+L++ G N + A DG
Sbjct: 104 ASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDG 163
Query: 999 WTPLHCAASCNNVQVCKFLVES 1020
+TPL A + Q L+E+
Sbjct: 164 FTPLAVALQQGHNQAVAILLEN 185
Score = 48.1 bits (113), Expect = 5e-05
Identities = 26/57 (45%), Positives = 36/57 (63%)
Query: 967 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
T LH A G TEIV+ L+Q + +AA ++G+TPLH +A V V L+E+GAA
Sbjct: 499 TPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAA 555
Score = 48.1 bits (113), Expect = 5e-05
Identities = 24/81 (29%), Positives = 41/81 (50%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G+ ++VQ ++ + P G T LH + G ++ L++ G + A G+TPL
Sbjct: 508 GKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPL 567
Query: 1003 HCAASCNNVQVCKFLVESGAA 1023
H AA ++ V K L++ AA
Sbjct: 568 HVAAKYGSLDVAKLLLQRRAA 588
Score = 47.4 bits (111), Expect = 8e-05
Identities = 28/98 (28%), Positives = 52/98 (53%)
Query: 931 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 990
N + L +S G ++V+ ++ +G+T LH A +GH ++V+ L++ G
Sbjct: 265 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 324
Query: 991 VNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 1028
+ A +G +PLH AA ++V+ K L++ A V +T
Sbjct: 325 LLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVT 362
Score = 47.0 bits (110), Expect = 1e-04
Identities = 27/86 (31%), Positives = 44/86 (51%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G ++V ++ P + N G TALH A AG E+V+ L++ G V+A + TPL
Sbjct: 442 GHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPL 501
Query: 1003 HCAASCNNVQVCKFLVESGAAVFAMT 1028
H A+ ++ + L++ A A T
Sbjct: 502 HIASRLGKTEIVQLLLQHMAHPDAAT 527
Score = 47.0 bits (110), Expect = 1e-04
Identities = 23/66 (34%), Positives = 36/66 (54%)
Query: 957 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 1016
+ ++ +G+T LH A GHT++V L+ G N++ + G T LH AA + V V
Sbjct: 654 ETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADI 713
Query: 1017 LVESGA 1022
L + GA
Sbjct: 714 LTKHGA 719
Score = 46.6 bits (109), Expect = 1e-04
Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 3/103 (2%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+S EG D+V ++ + + + G+T+LH A + L + G + +A G
Sbjct: 669 ASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLG 728
Query: 999 WTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 1038
+TPL A NV++ FL++ GA V A T Y+ + AA +
Sbjct: 729 YTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQ 771
Score = 45.4 bits (106), Expect = 3e-04
Identities = 25/64 (39%), Positives = 36/64 (56%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
G T L A G+ ++V FL++ G NVNA +G+TPLH AA + + L++ GA
Sbjct: 728 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKP 787
Query: 1025 FAMT 1028
A T
Sbjct: 788 NATT 791
Score = 45.1 bits (105), Expect = 4e-04
Identities = 24/64 (37%), Positives = 35/64 (54%)
Query: 963 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ G+T +H A GH IV L+Q G + + + G T LH AA V+V + L+ +GA
Sbjct: 429 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 488
Query: 1023 AVFA 1026
V A
Sbjct: 489 LVDA 492
Score = 45.1 bits (105), Expect = 4e-04
Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 5/108 (4%)
Query: 923 AHGMRVK--FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEI 980
AH + K F PL + ++ G D+ + ++ G+T LH A + ++
Sbjct: 555 AHSLATKKGFTPLHV---AAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKV 611
Query: 981 VKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 1028
L++ G + +A +G+TPLH AA N +Q+ L+ GA +T
Sbjct: 612 ALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVT 659
Score = 43.9 bits (102), Expect = 9e-04
Identities = 20/81 (24%), Positives = 44/81 (54%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G + + + ++ + +P+ G T LH A ++++ LV++G ++ A G TP+
Sbjct: 376 GHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPI 435
Query: 1003 HCAASCNNVQVCKFLVESGAA 1023
H AA ++ + L+++GA+
Sbjct: 436 HVAAFMGHLNIVLLLLQNGAS 456
Score = 42.0 bits (97), Expect = 0.003
Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 946 DLVQRIIYEVDDPSLPNDE-GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHC 1004
D V ++ E P L + G++ LH A H E VK L+Q V+ D T LH
Sbjct: 312 DQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHV 371
Query: 1005 AASCNNVQVCKFLVESGA 1022
AA C + +V K L++ A
Sbjct: 372 AAHCGHYRVTKLLLDKRA 389
Score = 40.8 bits (94), Expect = 0.007
Identities = 21/66 (31%), Positives = 32/66 (48%)
Query: 963 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ G T LH A G+ + L+ G V+ +G TPLH A+ N + K L++ G
Sbjct: 231 ESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGG 290
Query: 1023 AVFAMT 1028
+ A T
Sbjct: 291 QIDAKT 296
Score = 40.8 bits (94), Expect = 0.007
Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
Query: 914 LRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAV 973
L K G+++ AH ++ + PL + G +V ++ + + + G T LH A
Sbjct: 714 LTKHGADQDAH-TKLGYTPLIVACHY---GNVKMVNFLLKQGANVNAKTKNGYTPLHQAA 769
Query: 974 CAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 1013
GHT I+ L+Q G NA ++G T L A + V
Sbjct: 770 QQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISV 809
Score = 39.3 bits (90), Expect = 0.021
Identities = 21/75 (28%), Positives = 31/75 (41%)
Query: 958 PSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 1017
P G T LH A +I L+ +G N G TPLH A+ + + L
Sbjct: 622 PHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLL 681
Query: 1018 VESGAAVFAMTYSDM 1032
++ GA + T S +
Sbjct: 682 LDKGANIHMSTKSGL 696
Score = 38.1 bits (87), Expect = 0.048
Identities = 34/132 (25%), Positives = 49/132 (37%), Gaps = 40/132 (30%)
Query: 930 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFL----- 984
F PL + ++ E D+V+ ++ + S ++G T L A+ GH + V L
Sbjct: 131 FTPLYM---AAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDT 187
Query: 985 --------------------------------VQFGVNVNAADSDGWTPLHCAASCNNVQ 1012
VQ + VN G+TPLH AA NV
Sbjct: 188 KGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVN 247
Query: 1013 VCKFLVESGAAV 1024
V L+ GAAV
Sbjct: 248 VATLLLNRGAAV 259
Score = 33.9 bits (76), Expect = 0.90
Identities = 75/392 (19%), Positives = 148/392 (37%), Gaps = 52/392 (13%)
Query: 428 PSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVD---QSNAPPSFGTLRKN 484
P A P G + + P +E K+ + A+D +S A SF +
Sbjct: 3080 PDTTPARTPTEEGTPTSEQN----PFLFQEGKLFEMTRSGAIDMTKRSYADESFHFFQIG 3135
Query: 485 QSSEDILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVP 544
Q S + V P P+ T + + L +T +D+ PD S+++ +
Sbjct: 3136 QESREETLSEDVKEGATGADPLPLETSAESLALSESKETVDDEADLLPDDVSEEVEEIPA 3195
Query: 545 SMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQ-------ESPPAAAVRPFTPQPSK 597
S Q + S P+ + +S G+K + PP + V+ + S
Sbjct: 3196 S----DAQLNSQMGISASTETPT---KEAVSVGTKDLPTVQTGDIPPLSGVKQISCPDSS 3248
Query: 598 DTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSAL-------------TKTHTRG 644
+ P + Q ++ S+Y+ + + Q ++ T++ ++
Sbjct: 3249 E----PAVQVQLDFSTLTRSVYSDRGDDSPDSSPEEQKSVIEIPTAPMENVPFTESKSKI 3304
Query: 645 PHFSSVYGKPVIAAAQNQQQHPENIYSN-------SQGKPGSPEPETEPVSSVQE--NHE 695
P + P +A+ + E+ S+ + KP S P P+ V++ +
Sbjct: 3305 PVRTMPTSTPAPPSAEYESSVSEDFLSSVDEENKADEAKPKSKLPVKVPLQRVEQQLSDL 3364
Query: 696 NERIPRPLSPT-KLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPN 754
+ + + ++P + + ++ R++S++D +L K P+K R S TE E +
Sbjct: 3365 DTSVQKTVAPQGQDMASIAPDNRSKSESDASSLDSK---TKCPVKTR-SYTETETESRER 3420
Query: 755 IQKLLYQRTTIAAMETISVPSYPSKSASVTAS 786
++L + A I P KS S T+S
Sbjct: 3421 AEELELESEEGATRPKILTSRLPVKSRSTTSS 3452
Score = 33.5 bits (75), Expect = 1.2
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 26/186 (13%)
Query: 529 DIKPDGSSQQLSTVVPSMGTKPKPAGQ---QPRVLLSPSIPSVGQDQTLSPGSKQES--- 582
DI PD + PS+G K KP + + + + + + L GS +ES
Sbjct: 1681 DIPPDETQSTQKQHKPSLGIK-KPVRRKLKEKQKQKEEGLQASAEKAELKKGSSEESLGE 1739
Query: 583 PPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHT 642
P A P + L + + I S+ + +A K + Q +K
Sbjct: 1740 DPGLAPEPLPTVKATSPL---------IEETPIGSIKDKVKALQKRVEDE-QKGRSKLPI 1789
Query: 643 RGPHFSSVYGKPVIAAAQNQQQHPENIYS--NSQGKPGSPEPETEPVSSVQENHENERIP 700
R V GK + + HP S + + PGSP P+TE S++ + + ER P
Sbjct: 1790 R------VKGKEDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHP 1843
Query: 701 RPLSPT 706
P+SP+
Sbjct: 1844 -PVSPS 1848
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 68.2 bits (165), Expect = 4e-11
Identities = 108/490 (22%), Positives = 175/490 (35%), Gaps = 78/490 (15%)
Query: 472 SNAPPSFGTLRKNQSSEDILR----DAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPP 527
S+A P R S+ R +Q K + + PP T P++ P G + P
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 528 SDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLL---------SPSIPSVGQDQTLSPGS 578
++ P P PA P L SPS P Q P +
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363
Query: 579 K-QESPPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSAL 637
++PP+ P PS T+ PP + P ++ + S+ QAP A+ S
Sbjct: 364 PPSQAPPSMTTPPMQAPPSLQTI-PPIQVPHSLTSPSL-------QAPPSPL--ALSSLQ 413
Query: 638 TKTHTRGPHFSSVYGKPVIAAAQNQQQHPENIYSNSQGKPGSPEPETEPVSSVQENHENE 697
T P + + ++ Q Q S +P S P++ P+ + +
Sbjct: 414 ATTSLGSPTLQATHSFLTMSPRQTQAS------LTSPSRPASTPPDSPPLQAPLSLPASP 467
Query: 698 RIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLSNAPR---------PLKKRSSITEPE 748
+ LSP + LS+P L+AL S++P+ PL+ +SS+ P
Sbjct: 468 PLQTSLSPA--VSPLSSPLTIHP---LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPS 522
Query: 749 GPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASS------ESPVEIQ---NPYLH 799
P + + +++ P + SA +T +P +Q +P
Sbjct: 523 LQTPP----ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT 578
Query: 800 VEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNS-PNLQNNPEEP- 857
PE P +P + + + P SP P+ P + P LQ P P
Sbjct: 579 PPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638
Query: 858 ----------NPEAPHVLDVYLEEYPPYPPP------PY--PSGEPEGPGEDSVSMRPPE 899
+P+AP+ L V+L + P PPP P+ P+ P P S PP
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 698
Query: 900 ITG-QVSLPP 908
+ + +PP
Sbjct: 699 LAAPPLQVPP 708
Score = 34.7 bits (78), Expect = 0.53
Identities = 121/589 (20%), Positives = 179/589 (30%), Gaps = 82/589 (13%)
Query: 332 PVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRPELLVKPALPDGSLVIQASEGPM 391
P+ + +L + P P +P + P L L P
Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPL---ENLPSLAPPPLQTASAPLTTPHLETPPCPAPC 567
Query: 392 KIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPSQGSASVPQSTGNALDQVDDGEV 451
+Q P+ + +T S P P +P P QG S P S
Sbjct: 568 PLQAPPSPLTTPPPETPSSIATP--PPQAPPALASPPLQGLPSPPLS------------- 612
Query: 452 PLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTK 511
PL + P + +PP+ L + +A + A PP P+
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP-PSP 671
Query: 512 PKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQD 571
P Q P+ + P S S S P + P P P+ P +
Sbjct: 672 PVQA--PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP----------PASPPMSPS 719
Query: 572 QTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQ 631
T P ++PP A P PS PP P + +A+ + AP
Sbjct: 720 ATPPP----QAPPPLAAPPLQVPPS-----PPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
Query: 632 AVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENIYSNSQGKPGSPEPETEPVSSVQ 691
+ ++L + P + P A Q P S P SP P+S +
Sbjct: 771 SPPASLPMSPLAKPPPQA----PPALATPPLQALPSPPASFPGQAPFSPSASL-PMSPL- 824
Query: 692 ENHENERIPRPLSPTKL-LPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGP 750
P P +P L P L P + L+A R+ + P +T P
Sbjct: 825 ------ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878
Query: 751 NGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLV 810
P + + T+S P S+S T+ +P E++ PE +
Sbjct: 879 GPP-------PPPSRSPSSTLSGPDLAGHSSSATS---TPEELRG--YDSGPEGGAAASP 926
Query: 811 PESLSPEDVGNASTENSDMP------APSPGLDYEPEGVPDNSPNLQNNPEEPNPE---- 860
P A+ P AP L + P P ++ L E PE
Sbjct: 927 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 986
Query: 861 APHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPG 909
AP LD P P P G+ S R P+ LP G
Sbjct: 987 APGALD-------PGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLG 1028
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 67.8 bits (164), Expect = 6e-11
Identities = 43/221 (19%), Positives = 113/221 (51%), Gaps = 7/221 (3%)
Query: 113 KVPGEYRRKENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQ-- 170
K+ + +R+E R + + E +E Q++++ Q++ + +E+ + K+Q+Q
Sbjct: 465 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEE 524
Query: 171 --RQQQQVAEQEKLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQ 228
RQ++++ EQE++ R KE QE K++K E+K + + E E+ +
Sbjct: 525 MWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQE 584
Query: 229 QKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNA 288
+K RE + + EE R+ E + + + + + + E + +++Q + + + Q
Sbjct: 585 EKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE---EKMQEQEEKMRRQEE 641
Query: 289 KLQQQRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKE 329
K+++Q + + ++ ++ ++ + E +++W+++ + ++E
Sbjct: 642 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 682
Score = 55.5 bits (132), Expect = 3e-07
Identities = 60/317 (18%), Positives = 145/317 (45%), Gaps = 47/317 (14%)
Query: 20 EQHFTEVPVTPETICRDVVDLCKEPGESDCHLAEVWCGSERPVADNERMFDVLQRFGSQR 79
EQ + V + R + +L KE L E N ++ + LQ S++
Sbjct: 239 EQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK 298
Query: 80 NEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRRKENGVNSPRMDLTLAELQE 139
+E++ ++ + L+R + +P + + E D ELQ
Sbjct: 299 SEIQLNVKELKR--------------KLERAKLLLPQQQLQAE-------ADHLGKELQS 337
Query: 140 MASRQQQQIEAQQ---QLLATKEQRLKFLKQQDQRQQQQVAEQE-KLKRLKEIAENQEAK 195
++++ Q Q+E + +L +E+++ +++ Q ++++ EQE K++ +E QE K
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 397
Query: 196 LKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGR 255
+++ + E+K +++ E E+ ++Q E++ + EE R+LE
Sbjct: 398 MRRQEEMMWEKEEKMRRQEEMMWEKEEK----MRRQEEMMW---EKEEKIRELE------ 444
Query: 256 IDSHHDNQSAVAELDRLYKELQLRNK-LNQEQNAKLQQQRECLNKRNSEVAVMDKRVNEL 314
+ H+ + + ++ +E ++R + QEQ AK+ +Q E + ++ ++++ E
Sbjct: 445 -EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ-------EEKIREQ 496
Query: 315 RDRLWKKKAALQQKENL 331
+++W+++ + ++E +
Sbjct: 497 EEKMWRQEEKIHEQEKI 513
Score = 55.5 bits (132), Expect = 3e-07
Identities = 50/282 (17%), Positives = 126/282 (44%), Gaps = 52/282 (18%)
Query: 52 AEVWCGSERPVADNERMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNG 111
A++W E+ E++ + ++ Q ++ HE+ R+ R + + R
Sbjct: 477 AKMWRQEEKIREQEEKIREQEEKMWRQEEKI-----HEQEKIRE--EEKRQEQEEMWRQE 529
Query: 112 VKVPGE---YRRKENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQ 168
K+ + +R+KE + E +E +Q++++ Q++ + +E++++ +++
Sbjct: 530 EKIREQEEIWRQKEK----------IHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK 579
Query: 169 DQRQQQQVAEQE-KLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLF 227
RQ++++ EQE K++ +E QE ++ G E+K + ++E E+
Sbjct: 580 VWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 228 QQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQN 287
++K RE + + EE R+ E ++ QEQ
Sbjct: 640 EEKIREQEKKIREQEEKIREQE-------------------------------EMMQEQE 668
Query: 288 AKLQQQRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKE 329
K+ +Q E + ++ ++ ++++ +++W+++ L+Q+E
Sbjct: 669 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 710
Score = 52.0 bits (123), Expect = 3e-06
Identities = 43/208 (20%), Positives = 107/208 (51%), Gaps = 18/208 (8%)
Query: 146 QQIEAQ-QQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKR-LKEIAENQEAKLKKVRALK 203
+Q+E + + L++ KF + +Q +++K R ++E+ + ++A ++
Sbjct: 215 KQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNT 274
Query: 204 GHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE----MLKNGRIDSH 259
E+ + N KL E+++ L + ++ E+ L V+EL R+LE +L ++ +
Sbjct: 275 ITDEELKEKNAKLQEKLQ----LVESEKSEIQL---NVKELKRKLERAKLLLPQQQLQAE 327
Query: 260 HDN-----QSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNEL 314
D+ QS A+L +E +L N+LNQ+Q K+ +Q E + + ++ ++++ E
Sbjct: 328 ADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ 387
Query: 315 RDRLWKKKAALQQKENLPVSSDGNLPQQ 342
+++ +++ ++++E + + + +Q
Sbjct: 388 EEKIREQEEKMRRQEEMMWEKEEKMRRQ 415
Score = 33.1 bits (74), Expect = 1.5
Identities = 27/142 (19%), Positives = 65/142 (45%), Gaps = 9/142 (6%)
Query: 101 RSQDPSLKRNGVKV-PGEYRRKENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKE 159
R Q+ ++ K+ E +E + + E +E Q++++ Q++ + +E
Sbjct: 588 REQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI--RE 645
Query: 160 QRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEE 219
Q K +Q+++ ++Q+ QE+ +++ E +E ++ ++ E+ R K+ E+
Sbjct: 646 QEKKIREQEEKIREQEEMMQEQEEKM---WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702
Query: 220 ---IEQMNNLFQQKQRELVLAV 238
+ Q Q+ Q L A+
Sbjct: 703 EVRLRQQEEKMQEHQEHLEAAI 724
Score = 30.8 bits (68), Expect = 7.6
Identities = 39/153 (25%), Positives = 64/153 (41%), Gaps = 33/153 (21%)
Query: 205 HVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQS 264
H Q+ L +L ++ + L QK EL +A+ + +QLE I HD+
Sbjct: 176 HQHQEALRR-ELEAQVHTIRILTCQKT-ELQMALYYSQHAVKQLEGEARDLISRLHDSWK 233
Query: 265 AVAEL--------------DRLYKELQ----------LRNKLN----QEQNAKLQQQREC 296
EL DR +EL RN + +E+NAKLQ++ +
Sbjct: 234 FAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQL 293
Query: 297 LNKRNSEVAVMDKRVNELRDRLWKKKAALQQKE 329
+ SE+ + V EL+ +L + K L Q++
Sbjct: 294 VESEKSEIQL---NVKELKRKLERAKLLLPQQQ 323
>gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo
sapiens]
Length = 226
Score = 67.4 bits (163), Expect = 7e-11
Identities = 36/82 (43%), Positives = 50/82 (60%)
Query: 946 DLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCA 1005
+L + I+ + + + + TALH A AGHTEIV+FL+Q GV VN D GW+PLH A
Sbjct: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 1006 ASCNNVQVCKFLVESGAAVFAM 1027
AS ++ K L+ GA V A+
Sbjct: 81 ASAGRDEIVKALLGKGAQVNAV 102
Score = 54.3 bits (129), Expect = 6e-07
Identities = 29/61 (47%), Positives = 37/61 (60%)
Query: 962 NDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESG 1021
+D G + LH A AG EIVK L+ G VNA + +G TPLH AAS N ++ L+E G
Sbjct: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
Query: 1022 A 1022
A
Sbjct: 130 A 130
Score = 47.4 bits (111), Expect = 8e-05
Identities = 21/69 (30%), Positives = 37/69 (53%)
Query: 957 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 1016
+P + TA+H A G+ +++ L+ + + N D++G TPLH A V+ K
Sbjct: 131 NPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKL 190
Query: 1017 LVESGAAVF 1025
LV GA+++
Sbjct: 191 LVSQGASIY 199
Score = 30.8 bits (68), Expect = 7.6
Identities = 17/67 (25%), Positives = 31/67 (46%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
++ +G ++ ++Y ++ + EG T LH A E K LV G ++ + +
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 205
Query: 999 WTPLHCA 1005
TPL A
Sbjct: 206 KTPLQVA 212
>gi|28605137 proteasome 26S non-ATPase subunit 10 isform 2 [Homo
sapiens]
Length = 151
Score = 67.4 bits (163), Expect = 7e-11
Identities = 36/82 (43%), Positives = 50/82 (60%)
Query: 946 DLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCA 1005
+L + I+ + + + + TALH A AGHTEIV+FL+Q GV VN D GW+PLH A
Sbjct: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 1006 ASCNNVQVCKFLVESGAAVFAM 1027
AS ++ K L+ GA V A+
Sbjct: 81 ASAGRDEIVKALLGKGAQVNAV 102
Score = 54.3 bits (129), Expect = 6e-07
Identities = 29/61 (47%), Positives = 37/61 (60%)
Query: 962 NDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESG 1021
+D G + LH A AG EIVK L+ G VNA + +G TPLH AAS N ++ L+E G
Sbjct: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
Query: 1022 A 1022
A
Sbjct: 130 A 130
Score = 32.0 bits (71), Expect = 3.4
Identities = 19/65 (29%), Positives = 31/65 (47%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G ++V+ ++ + + N G T LH A EI L++ G N +A D T +
Sbjct: 84 GRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAM 143
Query: 1003 HCAAS 1007
H AA+
Sbjct: 144 HRAAA 148
>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
Length = 1897
Score = 67.0 bits (162), Expect = 1e-10
Identities = 35/84 (41%), Positives = 52/84 (61%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+S EG +V ++++ +G TALH A AG E+V+ LV +G NVNA G
Sbjct: 85 ASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKG 144
Query: 999 WTPLHCAASCNNVQVCKFLVESGA 1022
+TPL+ AA N+++V KFL+E+GA
Sbjct: 145 FTPLYMAAQENHLEVVKFLLENGA 168
Score = 63.2 bits (152), Expect = 1e-09
Identities = 32/84 (38%), Positives = 47/84 (55%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+S G +V+ ++ P++ N + T LH A AGHTE+ K+L+Q VNA D
Sbjct: 444 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD 503
Query: 999 WTPLHCAASCNNVQVCKFLVESGA 1022
TPLHCAA + + K L+E+ A
Sbjct: 504 QTPLHCAARIGHTNMVKLLLENNA 527
Score = 60.5 bits (145), Expect = 9e-09
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
Query: 942 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 1001
EG ++V ++ + + +L N G+T LH GH + L++ GV V+A G+TP
Sbjct: 678 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 737
Query: 1002 LHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 1038
LH A+ N+++ KFL++ A V A T YS + AA +
Sbjct: 738 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 777
Score = 54.7 bits (130), Expect = 5e-07
Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 3/79 (3%)
Query: 954 EVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 1013
E+DD +L + +T LH A GH + K L+ G N+ +G+TPLH A N+V+V
Sbjct: 363 EIDDITLDH---LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRV 419
Query: 1014 CKFLVESGAAVFAMTYSDM 1032
+ L+++GA++ A+T S +
Sbjct: 420 MELLLKTGASIDAVTESGL 438
Score = 50.1 bits (118), Expect = 1e-05
Identities = 26/83 (31%), Positives = 45/83 (54%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
++L G+ ++V+ ++ + + + +G T L+ A H E+VKFL++ G N N A DG
Sbjct: 118 AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDG 177
Query: 999 WTPLHCAASCNNVQVCKFLVESG 1021
+TPL A + V L+ G
Sbjct: 178 FTPLAVALQQGHENVVAHLINYG 200
Score = 49.7 bits (117), Expect = 2e-05
Identities = 27/69 (39%), Positives = 39/69 (56%)
Query: 963 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ G+T LH A GH IVK L+Q G + N ++ TPLH AA + +V K+L+++ A
Sbjct: 435 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKA 494
Query: 1023 AVFAMTYSD 1031
V A D
Sbjct: 495 KVNAKAKDD 503
Score = 48.5 bits (114), Expect = 4e-05
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 4/119 (3%)
Query: 948 VQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAA 1006
V ++ E D P+ G+T LH AV + +IVK L+ G + ++ +G+TPLH AA
Sbjct: 584 VAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAA 643
Query: 1007 SCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 1065
N V+V + L++ G + A +Q +EG+ + L Q + NK
Sbjct: 644 KQNQVEVARSLLQYGGSANA---ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNK 699
Score = 47.8 bits (112), Expect = 6e-05
Identities = 24/64 (37%), Positives = 36/64 (56%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
GIT LH A G+ +V+ L+ G + D TPLHCAA +V++ + L++ GA +
Sbjct: 272 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 331
Query: 1025 FAMT 1028
A T
Sbjct: 332 QAKT 335
Score = 47.0 bits (110), Expect = 1e-04
Identities = 31/103 (30%), Positives = 45/103 (43%)
Query: 920 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 979
ER AH N L L + D+V+ ++ P P G T LH A E
Sbjct: 590 ERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVE 649
Query: 980 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ + L+Q+G + NA G TPLH AA + ++ L+ A
Sbjct: 650 VARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQA 692
Score = 47.0 bits (110), Expect = 1e-04
Identities = 25/65 (38%), Positives = 33/65 (50%)
Query: 964 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
+G+T LH A GH E+V L+ N N + G TPLH A +V V L++ G
Sbjct: 667 QGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 726
Query: 1024 VFAMT 1028
V A T
Sbjct: 727 VDATT 731
Score = 46.2 bits (108), Expect = 2e-04
Identities = 26/62 (41%), Positives = 34/62 (54%)
Query: 967 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFA 1026
T LH A GHT +VK L++ N N A + G TPLH AA +V+ L+E A+
Sbjct: 505 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 564
Query: 1027 MT 1028
MT
Sbjct: 565 MT 566
Score = 46.2 bits (108), Expect = 2e-04
Identities = 24/82 (29%), Positives = 40/82 (48%)
Query: 942 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 1001
EG + V ++ + + +G T LH A G + + L++ + NAA +G TP
Sbjct: 546 EGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTP 605
Query: 1002 LHCAASCNNVQVCKFLVESGAA 1023
LH A NN+ + K L+ G +
Sbjct: 606 LHVAVHHNNLDIVKLLLPRGGS 627
Score = 45.1 bits (105), Expect = 4e-04
Identities = 20/58 (34%), Positives = 33/58 (56%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
G++ +H A H + V+ L+Q+ ++ D TPLH AA C + +V K L++ GA
Sbjct: 338 GLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 395
Score = 45.1 bits (105), Expect = 4e-04
Identities = 26/80 (32%), Positives = 40/80 (50%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G ++V+ ++ +P+L G T LH A GH E V L++ + G+TPL
Sbjct: 514 GHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 573
Query: 1003 HCAASCNNVQVCKFLVESGA 1022
H AA V+V + L+E A
Sbjct: 574 HVAAKYGKVRVAELLLERDA 593
Score = 45.1 bits (105), Expect = 4e-04
Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 9/102 (8%)
Query: 922 IAHGM------RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCA 975
I HG+ R+ + PL + +S G LV+ ++ D + G + LH A
Sbjct: 721 IKHGVMVDATTRMGYTPLHV---ASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 777
Query: 976 GHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 1017
GHT+IV L++ G + N SDG TPL A + V L
Sbjct: 778 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 819
Score = 45.1 bits (105), Expect = 4e-04
Identities = 23/59 (38%), Positives = 36/59 (61%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
G T LH A G+ ++VKFL+Q +VNA G++PLH AA + + L+++GA+
Sbjct: 734 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 792
Score = 44.7 bits (104), Expect = 5e-04
Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 955 VDDPSLPNDE---GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNV 1011
+D + PN G T LH A H +++ L++ G +++A G TPLH A+ ++
Sbjct: 391 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 450
Query: 1012 QVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 1065
+ K L++ GA + S+++ G+T+ +++L + K+ K
Sbjct: 451 PIVKNLLQRGA---SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 501
Score = 42.7 bits (99), Expect = 0.002
Identities = 22/76 (28%), Positives = 39/76 (51%)
Query: 957 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 1016
+P + + G T LH A + + + L+ G +VN +G TPLH A+ NV + +
Sbjct: 231 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 290
Query: 1017 LVESGAAVFAMTYSDM 1032
L++ GA + T ++
Sbjct: 291 LLDRGAQIETKTKDEL 306
Score = 38.9 bits (89), Expect = 0.028
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Query: 930 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 989
F PLA+ L +G ++V +I + + ALH A T L+Q
Sbjct: 178 FTPLAVALQ---QGHENVVAHLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 230
Query: 990 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
N + G+TPLH AA N+ V + L+ GA+V
Sbjct: 231 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 265
Score = 38.9 bits (89), Expect = 0.028
Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 3/107 (2%)
Query: 925 GMRVKFNP---LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIV 981
G V F P + L +S G +V+ ++ + +T LH A GH I
Sbjct: 262 GASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRIS 321
Query: 982 KFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 1028
+ L+ G + A +G +P+H AA +++ + L++ A + +T
Sbjct: 322 EILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 368
>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
Length = 1881
Score = 67.0 bits (162), Expect = 1e-10
Identities = 35/84 (41%), Positives = 52/84 (61%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+S EG +V ++++ +G TALH A AG E+V+ LV +G NVNA G
Sbjct: 52 ASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKG 111
Query: 999 WTPLHCAASCNNVQVCKFLVESGA 1022
+TPL+ AA N+++V KFL+E+GA
Sbjct: 112 FTPLYMAAQENHLEVVKFLLENGA 135
Score = 63.2 bits (152), Expect = 1e-09
Identities = 32/84 (38%), Positives = 47/84 (55%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+S G +V+ ++ P++ N + T LH A AGHTE+ K+L+Q VNA D
Sbjct: 411 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD 470
Query: 999 WTPLHCAASCNNVQVCKFLVESGA 1022
TPLHCAA + + K L+E+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNA 494
Score = 60.5 bits (145), Expect = 9e-09
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
Query: 942 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 1001
EG ++V ++ + + +L N G+T LH GH + L++ GV V+A G+TP
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 704
Query: 1002 LHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 1038
LH A+ N+++ KFL++ A V A T YS + AA +
Sbjct: 705 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744
Score = 54.7 bits (130), Expect = 5e-07
Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 3/79 (3%)
Query: 954 EVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 1013
E+DD +L + +T LH A GH + K L+ G N+ +G+TPLH A N+V+V
Sbjct: 330 EIDDITLDH---LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRV 386
Query: 1014 CKFLVESGAAVFAMTYSDM 1032
+ L+++GA++ A+T S +
Sbjct: 387 MELLLKTGASIDAVTESGL 405
Score = 50.1 bits (118), Expect = 1e-05
Identities = 26/83 (31%), Positives = 45/83 (54%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
++L G+ ++V+ ++ + + + +G T L+ A H E+VKFL++ G N N A DG
Sbjct: 85 AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDG 144
Query: 999 WTPLHCAASCNNVQVCKFLVESG 1021
+TPL A + V L+ G
Sbjct: 145 FTPLAVALQQGHENVVAHLINYG 167
Score = 49.7 bits (117), Expect = 2e-05
Identities = 27/69 (39%), Positives = 39/69 (56%)
Query: 963 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ G+T LH A GH IVK L+Q G + N ++ TPLH AA + +V K+L+++ A
Sbjct: 402 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKA 461
Query: 1023 AVFAMTYSD 1031
V A D
Sbjct: 462 KVNAKAKDD 470
Score = 48.5 bits (114), Expect = 4e-05
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 4/119 (3%)
Query: 948 VQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAA 1006
V ++ E D P+ G+T LH AV + +IVK L+ G + ++ +G+TPLH AA
Sbjct: 551 VAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAA 610
Query: 1007 SCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 1065
N V+V + L++ G + A +Q +EG+ + L Q + NK
Sbjct: 611 KQNQVEVARSLLQYGGSANA---ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNK 666
Score = 47.8 bits (112), Expect = 6e-05
Identities = 24/64 (37%), Positives = 36/64 (56%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
GIT LH A G+ +V+ L+ G + D TPLHCAA +V++ + L++ GA +
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298
Query: 1025 FAMT 1028
A T
Sbjct: 299 QAKT 302
Score = 47.0 bits (110), Expect = 1e-04
Identities = 31/103 (30%), Positives = 45/103 (43%)
Query: 920 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 979
ER AH N L L + D+V+ ++ P P G T LH A E
Sbjct: 557 ERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVE 616
Query: 980 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ + L+Q+G + NA G TPLH AA + ++ L+ A
Sbjct: 617 VARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQA 659
Score = 47.0 bits (110), Expect = 1e-04
Identities = 25/65 (38%), Positives = 33/65 (50%)
Query: 964 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
+G+T LH A GH E+V L+ N N + G TPLH A +V V L++ G
Sbjct: 634 QGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693
Query: 1024 VFAMT 1028
V A T
Sbjct: 694 VDATT 698
Score = 46.2 bits (108), Expect = 2e-04
Identities = 26/62 (41%), Positives = 34/62 (54%)
Query: 967 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFA 1026
T LH A GHT +VK L++ N N A + G TPLH AA +V+ L+E A+
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 531
Query: 1027 MT 1028
MT
Sbjct: 532 MT 533
Score = 46.2 bits (108), Expect = 2e-04
Identities = 24/82 (29%), Positives = 40/82 (48%)
Query: 942 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 1001
EG + V ++ + + +G T LH A G + + L++ + NAA +G TP
Sbjct: 513 EGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTP 572
Query: 1002 LHCAASCNNVQVCKFLVESGAA 1023
LH A NN+ + K L+ G +
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGS 594
Score = 45.1 bits (105), Expect = 4e-04
Identities = 20/58 (34%), Positives = 33/58 (56%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
G++ +H A H + V+ L+Q+ ++ D TPLH AA C + +V K L++ GA
Sbjct: 305 GLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 362
Score = 45.1 bits (105), Expect = 4e-04
Identities = 26/80 (32%), Positives = 40/80 (50%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G ++V+ ++ +P+L G T LH A GH E V L++ + G+TPL
Sbjct: 481 GHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 540
Query: 1003 HCAASCNNVQVCKFLVESGA 1022
H AA V+V + L+E A
Sbjct: 541 HVAAKYGKVRVAELLLERDA 560
Score = 45.1 bits (105), Expect = 4e-04
Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 9/102 (8%)
Query: 922 IAHGM------RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCA 975
I HG+ R+ + PL + +S G LV+ ++ D + G + LH A
Sbjct: 688 IKHGVMVDATTRMGYTPLHV---ASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744
Query: 976 GHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 1017
GHT+IV L++ G + N SDG TPL A + V L
Sbjct: 745 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 45.1 bits (105), Expect = 4e-04
Identities = 23/59 (38%), Positives = 36/59 (61%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
G T LH A G+ ++VKFL+Q +VNA G++PLH AA + + L+++GA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759
Score = 44.7 bits (104), Expect = 5e-04
Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 955 VDDPSLPNDE---GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNV 1011
+D + PN G T LH A H +++ L++ G +++A G TPLH A+ ++
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 417
Query: 1012 QVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 1065
+ K L++ GA + S+++ G+T+ +++L + K+ K
Sbjct: 418 PIVKNLLQRGA---SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 468
Score = 42.7 bits (99), Expect = 0.002
Identities = 22/76 (28%), Positives = 39/76 (51%)
Query: 957 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 1016
+P + + G T LH A + + + L+ G +VN +G TPLH A+ NV + +
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 257
Query: 1017 LVESGAAVFAMTYSDM 1032
L++ GA + T ++
Sbjct: 258 LLDRGAQIETKTKDEL 273
Score = 38.9 bits (89), Expect = 0.028
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Query: 930 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 989
F PLA+ L +G ++V +I + + ALH A T L+Q
Sbjct: 145 FTPLAVALQ---QGHENVVAHLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 197
Query: 990 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
N + G+TPLH AA N+ V + L+ GA+V
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 232
Score = 38.9 bits (89), Expect = 0.028
Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 3/107 (2%)
Query: 925 GMRVKFNP---LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIV 981
G V F P + L +S G +V+ ++ + +T LH A GH I
Sbjct: 229 GASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRIS 288
Query: 982 KFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 1028
+ L+ G + A +G +P+H AA +++ + L++ A + +T
Sbjct: 289 EILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 335
>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
Length = 1880
Score = 67.0 bits (162), Expect = 1e-10
Identities = 35/84 (41%), Positives = 52/84 (61%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+S EG +V ++++ +G TALH A AG E+V+ LV +G NVNA G
Sbjct: 52 ASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKG 111
Query: 999 WTPLHCAASCNNVQVCKFLVESGA 1022
+TPL+ AA N+++V KFL+E+GA
Sbjct: 112 FTPLYMAAQENHLEVVKFLLENGA 135
Score = 63.2 bits (152), Expect = 1e-09
Identities = 32/84 (38%), Positives = 47/84 (55%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+S G +V+ ++ P++ N + T LH A AGHTE+ K+L+Q VNA D
Sbjct: 411 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD 470
Query: 999 WTPLHCAASCNNVQVCKFLVESGA 1022
TPLHCAA + + K L+E+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNA 494
Score = 60.5 bits (145), Expect = 9e-09
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
Query: 942 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 1001
EG ++V ++ + + +L N G+T LH GH + L++ GV V+A G+TP
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 704
Query: 1002 LHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 1038
LH A+ N+++ KFL++ A V A T YS + AA +
Sbjct: 705 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744
Score = 54.7 bits (130), Expect = 5e-07
Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 3/79 (3%)
Query: 954 EVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 1013
E+DD +L + +T LH A GH + K L+ G N+ +G+TPLH A N+V+V
Sbjct: 330 EIDDITLDH---LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRV 386
Query: 1014 CKFLVESGAAVFAMTYSDM 1032
+ L+++GA++ A+T S +
Sbjct: 387 MELLLKTGASIDAVTESGL 405
Score = 50.1 bits (118), Expect = 1e-05
Identities = 26/83 (31%), Positives = 45/83 (54%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
++L G+ ++V+ ++ + + + +G T L+ A H E+VKFL++ G N N A DG
Sbjct: 85 AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDG 144
Query: 999 WTPLHCAASCNNVQVCKFLVESG 1021
+TPL A + V L+ G
Sbjct: 145 FTPLAVALQQGHENVVAHLINYG 167
Score = 49.7 bits (117), Expect = 2e-05
Identities = 27/69 (39%), Positives = 39/69 (56%)
Query: 963 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ G+T LH A GH IVK L+Q G + N ++ TPLH AA + +V K+L+++ A
Sbjct: 402 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKA 461
Query: 1023 AVFAMTYSD 1031
V A D
Sbjct: 462 KVNAKAKDD 470
Score = 48.5 bits (114), Expect = 4e-05
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 4/119 (3%)
Query: 948 VQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAA 1006
V ++ E D P+ G+T LH AV + +IVK L+ G + ++ +G+TPLH AA
Sbjct: 551 VAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAA 610
Query: 1007 SCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 1065
N V+V + L++ G + A +Q +EG+ + L Q + NK
Sbjct: 611 KQNQVEVARSLLQYGGSANA---ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNK 666
Score = 47.8 bits (112), Expect = 6e-05
Identities = 24/64 (37%), Positives = 36/64 (56%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
GIT LH A G+ +V+ L+ G + D TPLHCAA +V++ + L++ GA +
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298
Query: 1025 FAMT 1028
A T
Sbjct: 299 QAKT 302
Score = 47.0 bits (110), Expect = 1e-04
Identities = 31/103 (30%), Positives = 45/103 (43%)
Query: 920 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 979
ER AH N L L + D+V+ ++ P P G T LH A E
Sbjct: 557 ERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVE 616
Query: 980 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ + L+Q+G + NA G TPLH AA + ++ L+ A
Sbjct: 617 VARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQA 659
Score = 47.0 bits (110), Expect = 1e-04
Identities = 25/65 (38%), Positives = 33/65 (50%)
Query: 964 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
+G+T LH A GH E+V L+ N N + G TPLH A +V V L++ G
Sbjct: 634 QGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693
Query: 1024 VFAMT 1028
V A T
Sbjct: 694 VDATT 698
Score = 46.2 bits (108), Expect = 2e-04
Identities = 26/62 (41%), Positives = 34/62 (54%)
Query: 967 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFA 1026
T LH A GHT +VK L++ N N A + G TPLH AA +V+ L+E A+
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 531
Query: 1027 MT 1028
MT
Sbjct: 532 MT 533
Score = 46.2 bits (108), Expect = 2e-04
Identities = 24/82 (29%), Positives = 40/82 (48%)
Query: 942 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 1001
EG + V ++ + + +G T LH A G + + L++ + NAA +G TP
Sbjct: 513 EGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTP 572
Query: 1002 LHCAASCNNVQVCKFLVESGAA 1023
LH A NN+ + K L+ G +
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGS 594
Score = 45.1 bits (105), Expect = 4e-04
Identities = 20/58 (34%), Positives = 33/58 (56%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
G++ +H A H + V+ L+Q+ ++ D TPLH AA C + +V K L++ GA
Sbjct: 305 GLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 362
Score = 45.1 bits (105), Expect = 4e-04
Identities = 26/80 (32%), Positives = 40/80 (50%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G ++V+ ++ +P+L G T LH A GH E V L++ + G+TPL
Sbjct: 481 GHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 540
Query: 1003 HCAASCNNVQVCKFLVESGA 1022
H AA V+V + L+E A
Sbjct: 541 HVAAKYGKVRVAELLLERDA 560
Score = 45.1 bits (105), Expect = 4e-04
Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 9/102 (8%)
Query: 922 IAHGM------RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCA 975
I HG+ R+ + PL + +S G LV+ ++ D + G + LH A
Sbjct: 688 IKHGVMVDATTRMGYTPLHV---ASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744
Query: 976 GHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 1017
GHT+IV L++ G + N SDG TPL A + V L
Sbjct: 745 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 45.1 bits (105), Expect = 4e-04
Identities = 23/59 (38%), Positives = 36/59 (61%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
G T LH A G+ ++VKFL+Q +VNA G++PLH AA + + L+++GA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759
Score = 44.7 bits (104), Expect = 5e-04
Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 955 VDDPSLPNDE---GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNV 1011
+D + PN G T LH A H +++ L++ G +++A G TPLH A+ ++
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 417
Query: 1012 QVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 1065
+ K L++ GA + S+++ G+T+ +++L + K+ K
Sbjct: 418 PIVKNLLQRGA---SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 468
Score = 42.7 bits (99), Expect = 0.002
Identities = 22/76 (28%), Positives = 39/76 (51%)
Query: 957 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 1016
+P + + G T LH A + + + L+ G +VN +G TPLH A+ NV + +
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 257
Query: 1017 LVESGAAVFAMTYSDM 1032
L++ GA + T ++
Sbjct: 258 LLDRGAQIETKTKDEL 273
Score = 38.9 bits (89), Expect = 0.028
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Query: 930 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 989
F PLA+ L +G ++V +I + + ALH A T L+Q
Sbjct: 145 FTPLAVALQ---QGHENVVAHLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 197
Query: 990 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
N + G+TPLH AA N+ V + L+ GA+V
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 232
Score = 38.9 bits (89), Expect = 0.028
Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 3/107 (2%)
Query: 925 GMRVKFNP---LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIV 981
G V F P + L +S G +V+ ++ + +T LH A GH I
Sbjct: 229 GASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRIS 288
Query: 982 KFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 1028
+ L+ G + A +G +P+H AA +++ + L++ A + +T
Sbjct: 289 EILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 335
>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
Length = 1719
Score = 67.0 bits (162), Expect = 1e-10
Identities = 35/84 (41%), Positives = 52/84 (61%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+S EG +V ++++ +G TALH A AG E+V+ LV +G NVNA G
Sbjct: 52 ASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKG 111
Query: 999 WTPLHCAASCNNVQVCKFLVESGA 1022
+TPL+ AA N+++V KFL+E+GA
Sbjct: 112 FTPLYMAAQENHLEVVKFLLENGA 135
Score = 63.2 bits (152), Expect = 1e-09
Identities = 32/84 (38%), Positives = 47/84 (55%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+S G +V+ ++ P++ N + T LH A AGHTE+ K+L+Q VNA D
Sbjct: 411 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD 470
Query: 999 WTPLHCAASCNNVQVCKFLVESGA 1022
TPLHCAA + + K L+E+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNA 494
Score = 60.5 bits (145), Expect = 9e-09
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
Query: 942 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 1001
EG ++V ++ + + +L N G+T LH GH + L++ GV V+A G+TP
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 704
Query: 1002 LHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 1038
LH A+ N+++ KFL++ A V A T YS + AA +
Sbjct: 705 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744
Score = 54.7 bits (130), Expect = 5e-07
Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 3/79 (3%)
Query: 954 EVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 1013
E+DD +L + +T LH A GH + K L+ G N+ +G+TPLH A N+V+V
Sbjct: 330 EIDDITLDH---LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRV 386
Query: 1014 CKFLVESGAAVFAMTYSDM 1032
+ L+++GA++ A+T S +
Sbjct: 387 MELLLKTGASIDAVTESGL 405
Score = 50.1 bits (118), Expect = 1e-05
Identities = 26/83 (31%), Positives = 45/83 (54%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
++L G+ ++V+ ++ + + + +G T L+ A H E+VKFL++ G N N A DG
Sbjct: 85 AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDG 144
Query: 999 WTPLHCAASCNNVQVCKFLVESG 1021
+TPL A + V L+ G
Sbjct: 145 FTPLAVALQQGHENVVAHLINYG 167
Score = 49.7 bits (117), Expect = 2e-05
Identities = 27/69 (39%), Positives = 39/69 (56%)
Query: 963 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ G+T LH A GH IVK L+Q G + N ++ TPLH AA + +V K+L+++ A
Sbjct: 402 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKA 461
Query: 1023 AVFAMTYSD 1031
V A D
Sbjct: 462 KVNAKAKDD 470
Score = 48.5 bits (114), Expect = 4e-05
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 4/119 (3%)
Query: 948 VQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAA 1006
V ++ E D P+ G+T LH AV + +IVK L+ G + ++ +G+TPLH AA
Sbjct: 551 VAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAA 610
Query: 1007 SCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 1065
N V+V + L++ G + A +Q +EG+ + L Q + NK
Sbjct: 611 KQNQVEVARSLLQYGGSANA---ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNK 666
Score = 47.8 bits (112), Expect = 6e-05
Identities = 24/64 (37%), Positives = 36/64 (56%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
GIT LH A G+ +V+ L+ G + D TPLHCAA +V++ + L++ GA +
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298
Query: 1025 FAMT 1028
A T
Sbjct: 299 QAKT 302
Score = 47.0 bits (110), Expect = 1e-04
Identities = 31/103 (30%), Positives = 45/103 (43%)
Query: 920 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 979
ER AH N L L + D+V+ ++ P P G T LH A E
Sbjct: 557 ERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVE 616
Query: 980 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ + L+Q+G + NA G TPLH AA + ++ L+ A
Sbjct: 617 VARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQA 659
Score = 47.0 bits (110), Expect = 1e-04
Identities = 25/65 (38%), Positives = 33/65 (50%)
Query: 964 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
+G+T LH A GH E+V L+ N N + G TPLH A +V V L++ G
Sbjct: 634 QGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693
Query: 1024 VFAMT 1028
V A T
Sbjct: 694 VDATT 698
Score = 46.2 bits (108), Expect = 2e-04
Identities = 26/62 (41%), Positives = 34/62 (54%)
Query: 967 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFA 1026
T LH A GHT +VK L++ N N A + G TPLH AA +V+ L+E A+
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 531
Query: 1027 MT 1028
MT
Sbjct: 532 MT 533
Score = 46.2 bits (108), Expect = 2e-04
Identities = 24/82 (29%), Positives = 40/82 (48%)
Query: 942 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 1001
EG + V ++ + + +G T LH A G + + L++ + NAA +G TP
Sbjct: 513 EGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTP 572
Query: 1002 LHCAASCNNVQVCKFLVESGAA 1023
LH A NN+ + K L+ G +
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGS 594
Score = 45.1 bits (105), Expect = 4e-04
Identities = 20/58 (34%), Positives = 33/58 (56%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
G++ +H A H + V+ L+Q+ ++ D TPLH AA C + +V K L++ GA
Sbjct: 305 GLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 362
Score = 45.1 bits (105), Expect = 4e-04
Identities = 26/80 (32%), Positives = 40/80 (50%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G ++V+ ++ +P+L G T LH A GH E V L++ + G+TPL
Sbjct: 481 GHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 540
Query: 1003 HCAASCNNVQVCKFLVESGA 1022
H AA V+V + L+E A
Sbjct: 541 HVAAKYGKVRVAELLLERDA 560
Score = 45.1 bits (105), Expect = 4e-04
Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 9/102 (8%)
Query: 922 IAHGM------RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCA 975
I HG+ R+ + PL + +S G LV+ ++ D + G + LH A
Sbjct: 688 IKHGVMVDATTRMGYTPLHV---ASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744
Query: 976 GHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 1017
GHT+IV L++ G + N SDG TPL A + V L
Sbjct: 745 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 45.1 bits (105), Expect = 4e-04
Identities = 23/59 (38%), Positives = 36/59 (61%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
G T LH A G+ ++VKFL+Q +VNA G++PLH AA + + L+++GA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759
Score = 44.7 bits (104), Expect = 5e-04
Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 955 VDDPSLPNDE---GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNV 1011
+D + PN G T LH A H +++ L++ G +++A G TPLH A+ ++
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 417
Query: 1012 QVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 1065
+ K L++ GA + S+++ G+T+ +++L + K+ K
Sbjct: 418 PIVKNLLQRGA---SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 468
Score = 42.7 bits (99), Expect = 0.002
Identities = 22/76 (28%), Positives = 39/76 (51%)
Query: 957 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 1016
+P + + G T LH A + + + L+ G +VN +G TPLH A+ NV + +
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 257
Query: 1017 LVESGAAVFAMTYSDM 1032
L++ GA + T ++
Sbjct: 258 LLDRGAQIETKTKDEL 273
Score = 38.9 bits (89), Expect = 0.028
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Query: 930 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 989
F PLA+ L +G ++V +I + + ALH A T L+Q
Sbjct: 145 FTPLAVALQ---QGHENVVAHLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 197
Query: 990 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
N + G+TPLH AA N+ V + L+ GA+V
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 232
Score = 38.9 bits (89), Expect = 0.028
Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 3/107 (2%)
Query: 925 GMRVKFNP---LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIV 981
G V F P + L +S G +V+ ++ + +T LH A GH I
Sbjct: 229 GASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRIS 288
Query: 982 KFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 1028
+ L+ G + A +G +P+H AA +++ + L++ A + +T
Sbjct: 289 EILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 335
>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
Length = 1856
Score = 67.0 bits (162), Expect = 1e-10
Identities = 35/84 (41%), Positives = 52/84 (61%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+S EG +V ++++ +G TALH A AG E+V+ LV +G NVNA G
Sbjct: 52 ASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKG 111
Query: 999 WTPLHCAASCNNVQVCKFLVESGA 1022
+TPL+ AA N+++V KFL+E+GA
Sbjct: 112 FTPLYMAAQENHLEVVKFLLENGA 135
Score = 63.2 bits (152), Expect = 1e-09
Identities = 32/84 (38%), Positives = 47/84 (55%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
+S G +V+ ++ P++ N + T LH A AGHTE+ K+L+Q VNA D
Sbjct: 411 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD 470
Query: 999 WTPLHCAASCNNVQVCKFLVESGA 1022
TPLHCAA + + K L+E+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNA 494
Score = 60.5 bits (145), Expect = 9e-09
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
Query: 942 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 1001
EG ++V ++ + + +L N G+T LH GH + L++ GV V+A G+TP
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 704
Query: 1002 LHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 1038
LH A+ N+++ KFL++ A V A T YS + AA +
Sbjct: 705 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744
Score = 54.7 bits (130), Expect = 5e-07
Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 3/79 (3%)
Query: 954 EVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 1013
E+DD +L + +T LH A GH + K L+ G N+ +G+TPLH A N+V+V
Sbjct: 330 EIDDITLDH---LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRV 386
Query: 1014 CKFLVESGAAVFAMTYSDM 1032
+ L+++GA++ A+T S +
Sbjct: 387 MELLLKTGASIDAVTESGL 405
Score = 50.1 bits (118), Expect = 1e-05
Identities = 26/83 (31%), Positives = 45/83 (54%)
Query: 939 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
++L G+ ++V+ ++ + + + +G T L+ A H E+VKFL++ G N N A DG
Sbjct: 85 AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDG 144
Query: 999 WTPLHCAASCNNVQVCKFLVESG 1021
+TPL A + V L+ G
Sbjct: 145 FTPLAVALQQGHENVVAHLINYG 167
Score = 49.7 bits (117), Expect = 2e-05
Identities = 27/69 (39%), Positives = 39/69 (56%)
Query: 963 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ G+T LH A GH IVK L+Q G + N ++ TPLH AA + +V K+L+++ A
Sbjct: 402 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKA 461
Query: 1023 AVFAMTYSD 1031
V A D
Sbjct: 462 KVNAKAKDD 470
Score = 48.5 bits (114), Expect = 4e-05
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 4/119 (3%)
Query: 948 VQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAA 1006
V ++ E D P+ G+T LH AV + +IVK L+ G + ++ +G+TPLH AA
Sbjct: 551 VAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAA 610
Query: 1007 SCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 1065
N V+V + L++ G + A +Q +EG+ + L Q + NK
Sbjct: 611 KQNQVEVARSLLQYGGSANA---ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNK 666
Score = 47.8 bits (112), Expect = 6e-05
Identities = 24/64 (37%), Positives = 36/64 (56%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
GIT LH A G+ +V+ L+ G + D TPLHCAA +V++ + L++ GA +
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298
Query: 1025 FAMT 1028
A T
Sbjct: 299 QAKT 302
Score = 47.0 bits (110), Expect = 1e-04
Identities = 31/103 (30%), Positives = 45/103 (43%)
Query: 920 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 979
ER AH N L L + D+V+ ++ P P G T LH A E
Sbjct: 557 ERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVE 616
Query: 980 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
+ + L+Q+G + NA G TPLH AA + ++ L+ A
Sbjct: 617 VARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQA 659
Score = 47.0 bits (110), Expect = 1e-04
Identities = 25/65 (38%), Positives = 33/65 (50%)
Query: 964 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
+G+T LH A GH E+V L+ N N + G TPLH A +V V L++ G
Sbjct: 634 QGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693
Query: 1024 VFAMT 1028
V A T
Sbjct: 694 VDATT 698
Score = 46.2 bits (108), Expect = 2e-04
Identities = 26/62 (41%), Positives = 34/62 (54%)
Query: 967 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFA 1026
T LH A GHT +VK L++ N N A + G TPLH AA +V+ L+E A+
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 531
Query: 1027 MT 1028
MT
Sbjct: 532 MT 533
Score = 46.2 bits (108), Expect = 2e-04
Identities = 24/82 (29%), Positives = 40/82 (48%)
Query: 942 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 1001
EG + V ++ + + +G T LH A G + + L++ + NAA +G TP
Sbjct: 513 EGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTP 572
Query: 1002 LHCAASCNNVQVCKFLVESGAA 1023
LH A NN+ + K L+ G +
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGS 594
Score = 45.1 bits (105), Expect = 4e-04
Identities = 20/58 (34%), Positives = 33/58 (56%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
G++ +H A H + V+ L+Q+ ++ D TPLH AA C + +V K L++ GA
Sbjct: 305 GLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 362
Score = 45.1 bits (105), Expect = 4e-04
Identities = 26/80 (32%), Positives = 40/80 (50%)
Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
G ++V+ ++ +P+L G T LH A GH E V L++ + G+TPL
Sbjct: 481 GHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 540
Query: 1003 HCAASCNNVQVCKFLVESGA 1022
H AA V+V + L+E A
Sbjct: 541 HVAAKYGKVRVAELLLERDA 560
Score = 45.1 bits (105), Expect = 4e-04
Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 9/102 (8%)
Query: 922 IAHGM------RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCA 975
I HG+ R+ + PL + +S G LV+ ++ D + G + LH A
Sbjct: 688 IKHGVMVDATTRMGYTPLHV---ASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744
Query: 976 GHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 1017
GHT+IV L++ G + N SDG TPL A + V L
Sbjct: 745 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 45.1 bits (105), Expect = 4e-04
Identities = 23/59 (38%), Positives = 36/59 (61%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
G T LH A G+ ++VKFL+Q +VNA G++PLH AA + + L+++GA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759
Score = 44.7 bits (104), Expect = 5e-04
Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 955 VDDPSLPNDE---GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNV 1011
+D + PN G T LH A H +++ L++ G +++A G TPLH A+ ++
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 417
Query: 1012 QVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 1065
+ K L++ GA + S+++ G+T+ +++L + K+ K
Sbjct: 418 PIVKNLLQRGA---SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 468
Score = 42.7 bits (99), Expect = 0.002
Identities = 22/76 (28%), Positives = 39/76 (51%)
Query: 957 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 1016
+P + + G T LH A + + + L+ G +VN +G TPLH A+ NV + +
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 257
Query: 1017 LVESGAAVFAMTYSDM 1032
L++ GA + T ++
Sbjct: 258 LLDRGAQIETKTKDEL 273
Score = 38.9 bits (89), Expect = 0.028
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Query: 930 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 989
F PLA+ L +G ++V +I + + ALH A T L+Q
Sbjct: 145 FTPLAVALQ---QGHENVVAHLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 197
Query: 990 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
N + G+TPLH AA N+ V + L+ GA+V
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 232
Score = 38.9 bits (89), Expect = 0.028
Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 3/107 (2%)
Query: 925 GMRVKFNP---LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIV 981
G V F P + L +S G +V+ ++ + +T LH A GH I
Sbjct: 229 GASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRIS 288
Query: 982 KFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 1028
+ L+ G + A +G +P+H AA +++ + L++ A + +T
Sbjct: 289 EILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 335
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 66.2 bits (160), Expect = 2e-10
Identities = 36/84 (42%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Query: 965 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
G TALH A G+TE++K L+Q G +VN D DGWTPLH AA + C+ LV++
Sbjct: 112 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDN-LCD 170
Query: 1025 FAMTYSDMQTAADKCEEMEEGYTQ 1048
M QTA D +E GY +
Sbjct: 171 MEMVNKVGQTAFDVADEDILGYLE 194
Score = 60.1 bits (144), Expect = 1e-08
Identities = 32/67 (47%), Positives = 43/67 (64%), Gaps = 3/67 (4%)
Query: 980 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKC 1039
+VKFLV+ G N+N D++GW PLH AASC + + +FL+ GA V A+ S+ T D
Sbjct: 1 MVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN-SEGDTPLDIA 59
Query: 1040 EE--MEE 1044
EE MEE
Sbjct: 60 EEEAMEE 66
Score = 40.0 bits (92), Expect = 0.013
Identities = 19/45 (42%), Positives = 28/45 (62%)
Query: 961 PNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCA 1005
P++EG LH A G+ +I +FL+ G +V A +S+G TPL A
Sbjct: 15 PDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIA 59
>gi|41350198 fetal globin inducing factor [Homo sapiens]
Length = 239
Score = 64.7 bits (156), Expect = 5e-10
Identities = 37/103 (35%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
Query: 927 RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEG-ITALHNAVCAGHTEIVKFLV 985
+++ +P LLL ++ + V+R++ E DE T LH A +GH +IV+ L+
Sbjct: 69 KMEKDPSRLLLWAAEKNRLTTVRRLLSEKATHVNTRDEDEYTPLHRAAYSGHLDIVQELI 128
Query: 986 QFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 1028
G +V+A DGWTPLH A NN +V FL++ A + A T
Sbjct: 129 AQGADVHAVTVDGWTPLHSACKWNNTRVASFLLQHDADINAQT 171
Score = 46.2 bits (108), Expect = 2e-04
Identities = 29/95 (30%), Positives = 45/95 (47%)
Query: 912 TNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHN 971
T +R+ SE+ H + L ++ G D+VQ +I + D +G T LH+
Sbjct: 88 TTVRRLLSEKATHVNTRDEDEYTPLHRAAYSGHLDIVQELIAQGADVHAVTVDGWTPLHS 147
Query: 972 AVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAA 1006
A +T + FL+Q ++NA TPLH AA
Sbjct: 148 ACKWNNTRVASFLLQHDADINAQTKGLLTPLHLAA 182
Score = 39.7 bits (91), Expect = 0.016
Identities = 29/119 (24%), Positives = 49/119 (41%), Gaps = 3/119 (2%)
Query: 953 YEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQ 1012
Y + + + D L A T + + L + +VN D D +TPLH AA ++
Sbjct: 63 YRLQEKKMEKDPSRLLLWAAEKNRLTTVRRLLSEKATHVNTRDEDEYTPLHRAAYSGHLD 122
Query: 1013 VCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYAL 1071
+ + L+ GA V A+T C + T+ + FL + KG++ L
Sbjct: 123 IVQELIAQGADVHAVTVDGWTPLHSAC---KWNNTRVASFLLQHDADINAQTKGLLTPL 178
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 64.3 bits (155), Expect = 6e-10
Identities = 70/294 (23%), Positives = 125/294 (42%), Gaps = 76/294 (25%)
Query: 92 PGRDIVSG------------PRSQDPSLKRNGVKVPGEYRRKENGVNSPRMDLTLAELQE 139
PG D +SG P+ ++ S +R V P + +L L +L++
Sbjct: 37 PGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQ 96
Query: 140 MASRQQQ-------------------QIEAQQQLLATKEQR------------LKFLKQQ 168
QQQ Q + QQQL ++++ L+ + QQ
Sbjct: 97 QPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQ 156
Query: 169 DQRQQQQVAEQEKLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQ 228
Q Q QQV EQ++L++ +E + Q+A+ EQ+ L + +++ Q L Q
Sbjct: 157 QQLQPQQVQEQQRLQQQQEQLQTQQAQ-----------EQQVLQQQEQLQQQVQEQQLLQ 205
Query: 229 QKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNA 288
Q+Q +L + ++L +Q E L+ + + +L L ++ QL+ +L Q+Q A
Sbjct: 206 QQQEQL-----QQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQA 260
Query: 289 KLQQQRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQ 342
+LQQQ +++++ +L+ +L LQQ+E L L QQ
Sbjct: 261 QLQQQ------------LLEQQQAQLQQQL-----LLQQQEQLQQQQQQQLLQQ 297
Score = 57.4 bits (137), Expect = 8e-08
Identities = 60/278 (21%), Positives = 129/278 (46%), Gaps = 23/278 (8%)
Query: 129 RMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEI 188
R+ +LQ +++QQ ++ Q+QL +++ +QQ+Q QQQQ+ +Q++ + ++
Sbjct: 169 RLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQF 228
Query: 189 AENQEAKLKKVRAL----KGHVEQKRL--SNGKLVEE-IEQMNNLFQQ----KQRELVLA 237
+ QE ++ + L +G ++Q+ L +L ++ +EQ QQ +Q+E +
Sbjct: 229 QQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288
Query: 238 VSKVEELTRQLEMLKNGRIDSH--HDNQSAVAELDRLYKELQLRNKLNQE-QNAKLQQQR 294
+ + L +Q E L+ ++ + EL+ + +L +L Q+ Q + QQ+
Sbjct: 289 QQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQEL 348
Query: 295 ECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVG 354
E ++ + + + +L +L +++ L+Q+E + L Q + V
Sbjct: 349 ERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQ 408
Query: 355 PYIQSSTMP-------RMPSRPELLVKPALPDGSLVIQ 385
P +Q +P +P P +V P G +V+Q
Sbjct: 409 PELQLELVPAAGGGGAAVPGAPAAVV--VAPPGYVVVQ 444
Score = 55.5 bits (132), Expect = 3e-07
Identities = 62/274 (22%), Positives = 123/274 (44%), Gaps = 30/274 (10%)
Query: 136 ELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQE-- 193
+LQ ++QQ+++ QQ+ L T++ + + + QQ ++ QQQV EQ+ L++ +E + Q+
Sbjct: 158 QLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLL 217
Query: 194 AKLKKVRALKGHVEQKRLSNGK----LVEEIEQMNNLFQQKQREL--VLAVSKVEELTRQ 247
+ ++++ + +Q++L + L ++ + L QQ+Q +L L + +L +Q
Sbjct: 218 QQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQ 277
Query: 248 LEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQ---------------NAKLQQ 292
L + + ++ Q + ++L ++ L E+ +L+Q
Sbjct: 278 LLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQ 337
Query: 293 QRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAA 352
QR+ L +R E+ +R E R K + LQQ E L QQ
Sbjct: 338 QRQEL-ERQQEL----ERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVE 392
Query: 353 VGPYIQSSTMPRMPSRPELLVK--PALPDGSLVI 384
+G Q + P +PEL ++ PA G +
Sbjct: 393 LGAQQQEVQLELTPVQPELQLELVPAAGGGGAAV 426
Score = 39.7 bits (91), Expect = 0.016
Identities = 59/254 (23%), Positives = 115/254 (45%), Gaps = 53/254 (20%)
Query: 144 QQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAKLKKVRALK 203
QQQQ + QQQLL ++Q+ + +Q +QQ+Q+ +Q++ + L++ E
Sbjct: 256 QQQQAQLQQQLL--EQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQE------------- 300
Query: 204 GHVEQKRLSNGKLVEEIEQMNNLFQQKQRELV-LAVSKVEELTRQLEMLKNGRIDSHHDN 262
++Q++L L E E ++ + EL+ + + +EL +Q + L+ +
Sbjct: 301 -QLQQQQLQPPPLEPEEE------EEVELELMPVDLGSEQELEQQRQELERQQ------- 346
Query: 263 QSAVAELDRLYKELQLRNKLN---QEQNAKLQQQRECLNKRNSEVAVMDKRVNELRDRLW 319
EL+R ++ QL+ KL Q+ +L+QQ++ L ++ ++ + + + +
Sbjct: 347 -----ELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQ 401
Query: 320 KKKAALQ---QKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRPELLVKPA 376
+ +Q Q E +P + G A A VA G + EL+V PA
Sbjct: 402 LELTPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQ----------ELMVLPA 451
Query: 377 LPDGSLVIQASEGP 390
+ ++V A GP
Sbjct: 452 VAAPAVV--AIPGP 463
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 64.3 bits (155), Expect = 6e-10
Identities = 64/278 (23%), Positives = 128/278 (46%), Gaps = 23/278 (8%)
Query: 59 ERPVADNERMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEY 118
ER ER L+R +R E + LR E+ R R Q+ + ++ +
Sbjct: 326 ERREQQEERREQQLRREQEERREQQ--LRREQEEERREQQLRREQEEERREQQLRREQQL 383
Query: 119 RRKENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAE 178
RR++ ++ +E R++QQ+ +QQL +EQ+L+ +Q+++R +Q+ +
Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQL--RREQQLR-REQEEERHEQKHEQ 440
Query: 179 QEKLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAV 238
+ + +RLK E + LK+ + H +++R K +E E+ + ++ E
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEE----- 495
Query: 239 SKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLN 298
+ E+ R+ + L+ + + E +RL + L+ +L +EQ +++RE L
Sbjct: 496 -RREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ----EERREQLL 550
Query: 299 KRNSEVAVMDKR--------VNELRDRLWKKKAALQQK 328
KR E + +R E RD+L K++ +Q+
Sbjct: 551 KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588
Score = 57.8 bits (138), Expect = 6e-08
Identities = 57/262 (21%), Positives = 127/262 (48%), Gaps = 21/262 (8%)
Query: 72 LQRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRRKENGVNSPRMD 131
L+R G + + + R +R + R ++ L++ K+ E +++ +
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ 277
Query: 132 LTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAEN 191
L E QE+ +Q++ + QQ+L +EQ+L+ KQ+++R++QQ +E+ +R ++ E
Sbjct: 278 LRKLERQELRRERQEEEQQQQRL--RREQQLR-RKQEEERREQQEERREQQERREQQEER 334
Query: 192 QEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEML 251
+E +L++ + E++R + +E E+ +++Q E E +QL
Sbjct: 335 REQQLRREQ------EERREQQLRREQEEERREQQLRREQEE--------ERREQQLRRE 380
Query: 252 KNGRIDSHHDNQSAVAELDRLYKELQLR--NKLNQEQNAKLQQQ--RECLNKRNSEVAVM 307
+ R + + + +L +E QLR +L +EQ + +QQ RE +R+ +
Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Query: 308 DKRVNELRDRLWKKKAALQQKE 329
++R L+ +++ L+++E
Sbjct: 441 ERREQRLKREQEERRDWLKREE 462
Score = 54.7 bits (130), Expect = 5e-07
Identities = 64/262 (24%), Positives = 120/262 (45%), Gaps = 37/262 (14%)
Query: 73 QRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRRKENGVNSPRMDL 132
QR ++ E R +L+ E R + ++ +K E R+E + L
Sbjct: 445 QRLKREQEERRDWLKREEETER--------HEQERRKQQLKRDQEEERRERWLK-----L 491
Query: 133 TLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKE----- 187
E +E R++QQ+ +Q+ +EQRLK +++++R QQ++ +++L+R +E
Sbjct: 492 EEEERREQQERREQQLRREQE--ERREQRLK-RQEEEERLQQRLRSEQQLRREQEERREQ 548
Query: 188 -IAENQEAKLKKVR---ALKGHVEQKRLSNGKLVEE-------IEQMNNLFQQKQRELVL 236
+ +E +L++ R LK E++R K EE EQ L Q+ +RE
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE--- 605
Query: 237 AVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQ--EQNAKLQQQR 294
V ++E+ R+ + LK + Q +E ++ QLR + + EQ K +++
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Query: 295 ECLNKRNSEVAVMDKRVNELRD 316
E L +R ++R EL +
Sbjct: 666 ERLEQRLKREHEEERREQELAE 687
Score = 50.4 bits (119), Expect = 9e-06
Identities = 61/264 (23%), Positives = 124/264 (46%), Gaps = 42/264 (15%)
Query: 78 QRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRRKENGVNSPRMDLTLAEL 137
+ E++F E+ R+ R+Q + +G++ E RR + + L E
Sbjct: 827 REKELQFLEEEEQLQRRE-----RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEE 881
Query: 138 QEMASRQ-------QQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKE-IA 189
++ Q+Q+ +QQLL +E+ L Q+++R++++ EQE+ R +E +
Sbjct: 882 RKRRRHTLYAKPALQEQLRKEQQLLQEEEEEL----QREEREKRRRQEQERQYREEEQLQ 937
Query: 190 ENQEAKLKKVRALKGHVEQKR--LSNGKLVEEIEQMNNLFQQKQR--ELVLAVSKVEELT 245
+ +E L++ R + E++R + KL ++ EQ+ +K+R E + EEL
Sbjct: 938 QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ 997
Query: 246 RQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVA 305
++ E L + E +R Y++ +++L QE+ L+++RE
Sbjct: 998 QEEEQLLREEREKRRRQ-----EWERQYRK---KDELQQEEEQLLREERE---------- 1039
Query: 306 VMDKRVNELRDRLWKKKAALQQKE 329
KR + R+R ++++ LQQ+E
Sbjct: 1040 ---KRRLQERERQYREEEELQQEE 1060
Score = 48.5 bits (114), Expect = 4e-05
Identities = 56/240 (23%), Positives = 114/240 (47%), Gaps = 33/240 (13%)
Query: 119 RRKENGVNSPRMDLTLAELQEMASRQQQQIEA-QQQLLATKEQRLKFLKQQDQRQQQQVA 177
RR+E + L E +E R+Q++ +++ L +EQ KFL +++QR ++Q
Sbjct: 1330 RRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFL-EEEQRLRRQER 1388
Query: 178 EQEKLKRLKEI-AENQEAKLKKVRALKGHVEQKRLS--------------------NGKL 216
E++ LK +++ + +E +L++ R K E+++LS K
Sbjct: 1389 ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKF 1448
Query: 217 VEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKEL 276
+EE +Q+ +K RE + + EE +QL + R + Q E DR ++E
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREE--QQLHRQERDRKFLEEEQQLRRQERDRKFREQ 1506
Query: 277 QLRNK------LNQEQNAKLQQQRECLNKRNSEVAVMDK--RVNELRDRLWKKKAALQQK 328
+LR++ L +EQ QQ++ + ++ ++ + + RDR ++++ L+Q+
Sbjct: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566
Score = 47.0 bits (110), Expect = 1e-04
Identities = 49/228 (21%), Positives = 113/228 (49%), Gaps = 37/228 (16%)
Query: 138 QEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQE--AK 195
+E R++Q+ + Q++ LA E++ + ++ +QR +Q+ ++E ++ +E E +E A+
Sbjct: 131 EEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR-RDEELWRQRQEWQEREERRAE 189
Query: 196 LKKVRALKGH-----VEQKRLSNGKLVE------------EIEQMNNLFQQ------KQR 232
+++++ KGH ++++L +L+E E+ + +FQ+ ++R
Sbjct: 190 EEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKR 249
Query: 233 ELVLAVS----KVEELTRQLE-------MLKNGRIDSHHDNQSAVAELDRLYKELQLRNK 281
E VL + EE RQ E + K R + + Q + RL +E QLR K
Sbjct: 250 ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK 309
Query: 282 LNQEQNAKLQQQRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKE 329
+E+ + +++RE +R + ++++ ++ +++ +Q+E
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Score = 46.6 bits (109), Expect = 1e-04
Identities = 46/217 (21%), Positives = 107/217 (49%), Gaps = 19/217 (8%)
Query: 120 RKENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQ--RQQQQ-- 175
R+E ++ D E ++ RQ++ + ++Q L ++E KFL+++ Q RQQ+Q
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRK 1532
Query: 176 -VAEQEKLKRL---KEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQ 231
+ E+++L+R ++ ++++ K ++ L+ E+++LS +E ++ L +QK
Sbjct: 1533 FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR----QERDRKFRLEEQKV 1588
Query: 232 RELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQ 291
R +E+ Q + G+ + E ++L +E + + QE++ K
Sbjct: 1589 RRQEQERKFMED--EQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFL 1646
Query: 292 QQRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQK 328
++ L ++ E +++ RDR ++++ L Q+
Sbjct: 1647 EEEPQLRRQERE-----QQLRHDRDRKFREEEQLLQE 1678
Score = 45.8 bits (107), Expect = 2e-04
Identities = 64/259 (24%), Positives = 114/259 (44%), Gaps = 30/259 (11%)
Query: 66 ERMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRRKENGV 125
ER +L+R +R L ER R +D LKR + +R++
Sbjct: 544 ERREQLLKREEEKR------LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Query: 126 NSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRL 185
R+ E E R++Q+++ ++ ++Q LK +Q+++RQQQ EQ++ +
Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657
Query: 186 KEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELT 245
+ E +E +L++ R + H E++R +L EE Q++ RE + S++ +
Sbjct: 658 RLKREEEEERLEQ-RLKREHEEERR--EQELAEE-------EQEQARERI--KSRIPKWQ 705
Query: 246 RQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVA 305
QLE + R QS V R Q + QEQ K +++ L + E A
Sbjct: 706 WQLESEADAR-------QSKVYSRPR----KQEGQRRRQEQEEKRRRRESELQWQEEERA 754
Query: 306 VMDKRVNE-LRDRLWKKKA 323
++ E RD W+ +A
Sbjct: 755 HRQQQEEEQRRDFTWQWQA 773
Score = 45.1 bits (105), Expect = 4e-04
Identities = 58/249 (23%), Positives = 109/249 (43%), Gaps = 35/249 (14%)
Query: 113 KVPGEYRRKENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATK----------EQRL 162
K G+ RR+E R + L +E + +QQQ E Q++ + QRL
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRL 784
Query: 163 KF---LKQQDQRQ----QQQVAEQEKLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGK 215
L++Q +RQ ++Q EQ L +E + + + ++ + L+ E+++L +
Sbjct: 785 SARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRE 844
Query: 216 LVEEIEQMNNLFQQKQRELVLAVSKVEELTR-QLEMLKNGRIDSHHDNQSAVAELDRLYK 274
+++++ + Q+ Q + ++ R QLE + R H + A ++L K
Sbjct: 845 RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR---RHTLYAKPALQEQLRK 901
Query: 275 ELQL----RNKLNQEQNAKLQQQRECLNKRNSEVAVM----------DKRVNELRDRLWK 320
E QL +L +E+ K ++Q + R E +KR + R+R ++
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR 961
Query: 321 KKAALQQKE 329
K LQQKE
Sbjct: 962 KDKKLQQKE 970
Score = 44.3 bits (103), Expect = 7e-04
Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 17/211 (8%)
Query: 121 KENGVNSPRMDLTLAELQEMASRQQQQIE--AQQQLLATKEQRLKFLKQQDQRQQQQVAE 178
+E + D E ++ RQ+++ + ++Q L +E KF +++ RQ+ + +
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ 1739
Query: 179 QEKLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAV 238
+ +R ++I E ++ +R + + +R + E EQ+ +Q++ E L
Sbjct: 1740 LRRQERYRKILEEEQ-----LRPEREEQQLRRQERDRKFREEEQL----RQEREEQQLRS 1790
Query: 239 SKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLN 298
+ + R+ E L+ R + Q + ++LQL +EQ +L+Q+R+
Sbjct: 1791 QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL-----EEQEQRLRQERDRQY 1845
Query: 299 KRNSEVAVMDKRVNELRDRLWKKKAALQQKE 329
+ + A +K E LW+++ +++E
Sbjct: 1846 RAEEQFATQEKSRRE-EQELWQEEEQKRRQE 1875
Score = 43.1 bits (100), Expect = 0.001
Identities = 58/301 (19%), Positives = 131/301 (43%), Gaps = 48/301 (15%)
Query: 40 LCKEPGESDCHLAEVWCGSERPVADNERMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSG 99
L +EP + E C E + E +R +R E+ R E ++
Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153
Query: 100 PRSQDPSLKRNGVKVPGEYRRKENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKE 159
R + KR ++ +YR +E ELQ + ++QLL ++
Sbjct: 1154 LREEPE--KRRRQELERQYREEE-------------ELQ----------QEEEQLLREEQ 1188
Query: 160 QRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAKLK------KVRALKGHVEQKRLSN 213
++ + +++ R+++++ Q++ +R ++ E+Q + LK K A++ + +
Sbjct: 1189 EKRRQERERQYREEEELQRQKRKQRYRD--EDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 214 GKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLY 273
+ ++E +Q Q++L + + +E R+ E + + D H + + ++
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ-- 1304
Query: 274 KELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNELRDRLWK-KKAALQQKENLP 332
KE + R++ +QE+ L+++RE +KR + DR ++ ++ LQ++E P
Sbjct: 1305 KEAKRRDRKSQEEKQLLREERE------------EKRRRQETDRKFREEEQLLQEREEQP 1352
Query: 333 V 333
+
Sbjct: 1353 L 1353
Score = 41.6 bits (96), Expect = 0.004
Identities = 42/193 (21%), Positives = 91/193 (47%), Gaps = 23/193 (11%)
Query: 138 QEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAKLK 197
Q++ + ++ +QLL +R++QQ+ QE+ ++ E E Q + +
Sbjct: 1611 QQLRQERDRKFREDEQLLQ-------------EREEQQLHRQERDRKFLE-EEPQLRRQE 1656
Query: 198 KVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRID 257
+ + L+ ++K +L++E E+ Q++ R K E +QL + R
Sbjct: 1657 REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDR-------KFREEEQQLRRQERERKF 1709
Query: 258 SHHDNQSAVAELDRLYK-ELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRV-NELR 315
+ Q EL+R ++ E QLR + QEQ + ++ R+ L + ++++ + R
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769
Query: 316 DRLWKKKAALQQK 328
DR ++++ L+Q+
Sbjct: 1770 DRKFREEEQLRQE 1782
Score = 40.8 bits (94), Expect = 0.007
Identities = 58/280 (20%), Positives = 123/280 (43%), Gaps = 39/280 (13%)
Query: 86 LRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYR--RKENGVNSPRMDLTLAELQEMASR 143
LRH+ + + R + +R +K + R +E + R D E ++ SR
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR-DRKFREEEQQLSR 1425
Query: 144 QQQQI---EAQQQLLATKEQRLKFLKQQDQ------------------RQQQQVAEQEKL 182
Q++ E +QQ+ + +R KFL+++ Q R++QQ+ QE+
Sbjct: 1426 QERDRKFREEEQQVRRQERER-KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD 1484
Query: 183 KRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVE 242
++ E E Q + ++ R + + + K +EE +Q++ QQ+QR+ +
Sbjct: 1485 RKFLE-EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR--QQRQRKFL------- 1534
Query: 243 ELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNS 302
+ +QL + G+ D E ++L +E + + QE++ K + + + + ++
Sbjct: 1535 QEEQQLRRQERGQ-QRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 303 EVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQ 342
E M+ +E + R + + L+Q+ + D L Q+
Sbjct: 1594 ERKFME---DEQQLRRQEGQQQLRQERDRKFREDEQLLQE 1630
Score = 40.4 bits (93), Expect = 0.010
Identities = 49/217 (22%), Positives = 98/217 (45%), Gaps = 18/217 (8%)
Query: 108 KRNGVKVPGEYRRKENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQ 167
KR + +YR+K+ L + +++Q +++L +EQ L ++
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG--EE 1067
Query: 168 QDQRQQQQVAEQEKLKRLKEIAENQEAKLKKVRALKGHVEQKR--LSNGKLVEEIEQMNN 225
++ R++Q++ Q ++ +E+ + +E L++ + E++R +L +E EQ+
Sbjct: 1068 RETRRRQELERQ--YRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Query: 226 LFQQKQR--ELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKE----LQLR 279
++K+R EL + EE+ ++ E L + EL+R Y+E Q
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQ-----ELERQYREEEELQQEE 1180
Query: 280 NKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNELRD 316
+L +E+ K +Q+RE R E KR RD
Sbjct: 1181 EQLLREEQEKRRQERE-RQYREEEELQRQKRKQRYRD 1216
Score = 39.3 bits (90), Expect = 0.021
Identities = 43/232 (18%), Positives = 99/232 (42%), Gaps = 27/232 (11%)
Query: 117 EYRRKENGVNSPRMDLTLAELQEMASRQQQQIEAQ--QQLLATKEQRLKFLKQQDQRQQ- 173
+ RR+E +L E + ++QQ+ Q Q+ +EQ+L+ ++ QR+Q
Sbjct: 1493 QLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD 1552
Query: 174 --------QQVAEQEKLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNN 225
+Q+ ++ + ++L +++ +L++ + + E+K + + + + E
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Query: 226 LFQQKQR-----ELVLAVSKVEELTRQLEMLK-----------NGRIDSHHDNQSAVAEL 269
L Q++ R E +L + ++L RQ K HD E
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 270 DRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNELRDRLWKK 321
++L +E + + QE++ K +++ + L ++ E + + R L +K
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERK 1724
Score = 38.9 bits (89), Expect = 0.028
Identities = 44/187 (23%), Positives = 91/187 (48%), Gaps = 19/187 (10%)
Query: 134 LAELQEMASRQ--QQQIEAQQQLLATKEQRLKF--LKQQDQRQQQQVAEQEKLKRLKEIA 189
L E +E RQ ++Q +++L +EQ L+ K++ Q +++Q E+E+L++ +E
Sbjct: 1064 LGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL 1123
Query: 190 ENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQR--ELVLAVSKVEELTRQ 247
+E + ++ + +E++ ++ +E EQ+ +K+R EL + EEL ++
Sbjct: 1124 LREEREKRR----RQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
Query: 248 LEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLN---KRNSEV 304
E L + + E +R Y+E + + ++Q + + QR L + E
Sbjct: 1180 EEQL------LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKEN 1233
Query: 305 AVMDKRV 311
AV D +V
Sbjct: 1234 AVRDNKV 1240
Score = 38.1 bits (87), Expect = 0.048
Identities = 46/203 (22%), Positives = 96/203 (47%), Gaps = 33/203 (16%)
Query: 134 LAELQEMASRQ--QQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAEN 191
L E +E RQ ++Q + +L +EQ L+ ++R+++++ E+E+ R +E +
Sbjct: 1004 LREEREKRRRQEWERQYRKKDELQQEEEQLLR-----EEREKRRLQERERQYREEEELQQ 1058
Query: 192 QEAKL---KKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQR--ELVLAVSKVEELTR 246
+E +L ++ + +E++ +L +E EQ+ +K+R E + EEL +
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118
Query: 247 QLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAV 306
+ E L + EL+R Y+E ++ QE+ L+++ E
Sbjct: 1119 EEEQLLREEREKRRRQ-----ELERQYRE---EEEVQQEEEQLLREEPE----------- 1159
Query: 307 MDKRVNELRDRLWKKKAALQQKE 329
KR + +R ++++ LQQ+E
Sbjct: 1160 --KRRRQELERQYREEEELQQEE 1180
Score = 36.2 bits (82), Expect = 0.18
Identities = 40/204 (19%), Positives = 97/204 (47%), Gaps = 19/204 (9%)
Query: 138 QEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAKLK 197
Q++ + ++ ++QLL E+ QQ +RQ++ +E+ ++L+ ++ +
Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEE------QQLRRQERDRKFREEEQQLRRQERERKFLQE 1712
Query: 198 KVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELV----LAVSKVEELTRQLEMLKN 253
+ + + +E+K +L +E EQ Q++ R+++ L + E+ R+ E +
Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Query: 254 GRID-----SHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQ--RECLNKRNSEVAV 306
R + + Q E DR ++E + + +EQ + QQ+ + + ++
Sbjct: 1773 FREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEE 1832
Query: 307 MDKRVNELRDRLWK--KKAALQQK 328
++R+ + RDR ++ ++ A Q+K
Sbjct: 1833 QEQRLRQERDRQYRAEEQFATQEK 1856
Score = 35.8 bits (81), Expect = 0.24
Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 13/104 (12%)
Query: 120 RKENGVNSPRMDLTLAELQEMAS-RQQQQIEAQQQ-----------LLATKEQRLKFLKQ 167
R+E + S D E +++ R++QQ+ QQ+ L +EQRL+ +
Sbjct: 1783 REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERD 1842
Query: 168 QDQRQQQQVAEQEKLKR-LKEIAENQEAKLKKVRALKGHVEQKR 210
+ R ++Q A QEK +R +E+ + +E K ++ R K E R
Sbjct: 1843 RQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIR 1886
Score = 34.7 bits (78), Expect = 0.53
Identities = 46/212 (21%), Positives = 100/212 (47%), Gaps = 24/212 (11%)
Query: 136 ELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAK 195
+LQ + QQ++ Q++ +QR + +++Q +++ EQ++ KR ++ ++
Sbjct: 1266 DLQHLLGEQQERDREQER--RRWQQRDRHFPEEEQLERE---EQKEAKRRDRKSQEEKQL 1320
Query: 196 LKKVRALK---GHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLK 252
L++ R K ++K +L++E E+ Q++ R+ + EEL Q +
Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF-----REEELRHQ----E 1371
Query: 253 NGRIDSHHDNQSAVAELDR--LYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKR 310
GR + + E +R L +E QLR QE+ +L+Q R+ K E + ++
Sbjct: 1372 QGRKFLEEEQRLRRQERERKFLKEEQQLR---CQEREQQLRQDRD--RKFREEEQQLSRQ 1426
Query: 311 VNELRDRLWKKKAALQQKENLPVSSDGNLPQQ 342
+ + R +++ Q++E + + L Q+
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,785,542
Number of Sequences: 37866
Number of extensions: 2948344
Number of successful extensions: 28184
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 660
Number of HSP's successfully gapped in prelim test: 1654
Number of HSP's that attempted gapping in prelim test: 14134
Number of HSP's gapped (non-prelim): 10370
length of query: 1134
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1021
effective length of database: 13,968,660
effective search space: 14262001860
effective search space used: 14262001860
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.