BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|10092687 NIPA-like domain containing 3 [Homo sapiens] (406 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|10092687 NIPA-like domain containing 3 [Homo sapiens] 797 0.0 gi|13376097 NIPA-like domain containing 2 [Homo sapiens] 310 2e-84 gi|46409302 NIPA-like domain containing 1 [Homo sapiens] 125 7e-29 gi|149944536 ichthyin protein [Homo sapiens] 125 9e-29 gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2 is... 120 2e-27 gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2 is... 120 2e-27 gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2 is... 120 2e-27 gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1 is... 107 2e-23 gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2 is... 102 5e-22 gi|214010179 non-imprinted in Prader-Willi/Angelman syndrome 1 i... 94 2e-19 gi|238859647 G protein-coupled receptor 128 [Homo sapiens] 32 0.79 gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B ... 32 1.3 gi|116517313 mannose-P-dolichol utilization defect 1 [Homo sapiens] 30 3.0 gi|153945846 inositol 1,4,5-triphosphate receptor, type 3 [Homo ... 30 3.9 gi|223029454 solute carrier family 46, member 2 [Homo sapiens] 29 6.7 gi|21389515 ring finger protein 145 [Homo sapiens] 29 6.7 gi|26638655 potassium voltage-gated channel KQT-like protein 4 i... 29 8.7 gi|26638653 potassium voltage-gated channel KQT-like protein 4 i... 29 8.7 gi|4885441 solute carrier family 17 (sodium phosphate), member 4... 29 8.7 >gi|10092687 NIPA-like domain containing 3 [Homo sapiens] Length = 406 Score = 797 bits (2058), Expect = 0.0 Identities = 406/406 (100%), Positives = 406/406 (100%) Query: 1 MDGSHSAALKLQQLPPTSSSSAVSEASFSYKENLIGALLAIFGHLVVSIALNLQKYCHIR 60 MDGSHSAALKLQQLPPTSSSSAVSEASFSYKENLIGALLAIFGHLVVSIALNLQKYCHIR Sbjct: 1 MDGSHSAALKLQQLPPTSSSSAVSEASFSYKENLIGALLAIFGHLVVSIALNLQKYCHIR 60 Query: 61 LAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIF 120 LAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIF Sbjct: 61 LAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIF 120 Query: 121 IKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYM 180 IKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYM Sbjct: 121 IKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYM 180 Query: 181 LVEIILFCLLLYFYKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYP 240 LVEIILFCLLLYFYKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYP Sbjct: 181 LVEIILFCLLLYFYKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYP 240 Query: 241 IFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDV 300 IFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDV Sbjct: 241 IFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDV 300 Query: 301 LHICMFALGCLIAFLGVFLITRNRKKPIPFEPYISMDAMPGMQNMHDKGMTVQPELKASF 360 LHICMFALGCLIAFLGVFLITRNRKKPIPFEPYISMDAMPGMQNMHDKGMTVQPELKASF Sbjct: 301 LHICMFALGCLIAFLGVFLITRNRKKPIPFEPYISMDAMPGMQNMHDKGMTVQPELKASF 360 Query: 361 SYGALENNDNISEIYAPATLPVMQEEHGSRSASGVPYRVLEHTKKE 406 SYGALENNDNISEIYAPATLPVMQEEHGSRSASGVPYRVLEHTKKE Sbjct: 361 SYGALENNDNISEIYAPATLPVMQEEHGSRSASGVPYRVLEHTKKE 406 >gi|13376097 NIPA-like domain containing 2 [Homo sapiens] Length = 368 Score = 310 bits (793), Expect = 2e-84 Identities = 158/343 (46%), Positives = 225/343 (65%), Gaps = 14/343 (4%) Query: 4 SHSAALKLQQLPPTSSSSAVSEASFS---YKEN---LIGALLAIFGHLVVSIALNLQKYC 57 S SAAL L T + S S Y+ N L G LLAI G+LV+SI+LN+QKY Sbjct: 12 SASAALDELSLNFTYGAPGAGNGSLSGDWYRRNQIHLFGVLLAILGNLVISISLNIQKYS 71 Query: 58 HIRLAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIG 117 H++LA + PR YFK+ WW G+ LM +GE G FA+Y FAP++LI PL VSV SAII Sbjct: 72 HLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYGFAPITLIAPLGCVSVTGSAIIS 131 Query: 118 IIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFL 177 + F+K+ + D L G LA GTYLLV FAPN + ++ V +LV W FL Sbjct: 132 VTFLKDNLRASDLL--------GTTLAFAGTYLLVNFAPNITQAISARTVQYYLVGWQFL 183 Query: 178 LYMLVEIILFCLLLYFYKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQL 237 +Y+++EI++FC+LLYFYK K ++V++L LVA+L S+TV++VKAV+GM+ S+ +QL Sbjct: 184 IYVILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISVKAVSGMITFSVMDKMQL 243 Query: 238 DYPIFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIG 297 YPIFY+MF+ M+A+ V+Q FL+QA+++Y+++ + V +I T AI AG IFY +F+G Sbjct: 244 TYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAGIIFYQEFLG 303 Query: 298 EDVLHICMFALGCLIAFLGVFLITRNRKKPIPFEPYISMDAMP 340 L + ++ GC ++FLGVFL+TRNR+K + YI +P Sbjct: 304 APFLTVFIYLFGCFLSFLGVFLVTRNREKEHLQQSYIDFGNIP 346 >gi|46409302 NIPA-like domain containing 1 [Homo sapiens] Length = 410 Score = 125 bits (314), Expect = 7e-29 Identities = 78/293 (26%), Positives = 148/293 (50%), Gaps = 15/293 (5%) Query: 35 IGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWLGLFLMLLGEL 88 +G +LA+ + + + L+K ++LA RA Y K WW+GL M GE Sbjct: 70 VGLVLAVSSSIFIGSSFILKKKGLLQLASKGFTRAGQGGHSYLKEWLWWVGLLSMGAGEA 129 Query: 89 GVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGT 148 FA+YAFAP +L+ PL A+SV+ SAI+ F+ E + +GC L+++G+ Sbjct: 130 ANFAAYAFAPATLVTPLGALSVLISAILSSYFLNEHLN--------IHGKIGCILSILGS 181 Query: 149 YLLVTFAPNSHEKMTGENVTRHLVSWPFLLY-MLVEIILFCLLLYFYKEKNANNIVVILL 207 ++V AP E + + L F+ + +++ +I L+L +K NI+V + Sbjct: 182 TVMVIHAPQEEEVTSLHEMEMKLRDPGFISFAVIITVISLVLILIVAPKKGQTNILVYIS 241 Query: 208 LVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMY 267 + +L+G+ +V +VK + + I+ +P+ +V+ +V + Q +L++A + Sbjct: 242 ICSLIGAFSVSSVKGLGIAIKELIEWKPVYKHPLVFVLLAVLVLSVTTQINYLNKALDTF 301 Query: 268 DSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLI 320 ++SL+ + Y+ T++ +T AI + ++ G I G +G+FL+ Sbjct: 302 NTSLVTPIYYVFFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIFLL 354 >gi|149944536 ichthyin protein [Homo sapiens] Length = 466 Score = 125 bits (313), Expect = 9e-29 Identities = 83/326 (25%), Positives = 162/326 (49%), Gaps = 25/326 (7%) Query: 11 LQQLPPTSSSSAVSEASF-SYKENL-------IGALLAIFGHLVVSIALNLQKYCHIRLA 62 L Q+ S S A+F S++E + IG LA ++ ++ L+K +RL Sbjct: 88 LCQIVNDLSPEVPSNATFHSWQERIRQNYGFYIGLGLAFLSSFLIGSSVILKKKGLLRLV 147 Query: 63 GSKDPRA------YFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAII 116 + RA Y K WW G M GE+ F +YAFAP +++ PL A+SV+ SAI+ Sbjct: 148 ATGATRAVDGGFGYLKDAMWWAGFLTMAAGEVANFGAYAFAPATVVTPLGALSVLISAIL 207 Query: 117 GIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPF 176 F++E +L +GC + V G+ ++V AP + T + + F Sbjct: 208 SSYFLRESLN--------LLGKLGCVICVAGSTVMVIHAPEEEKVTTIMEMASKMKDTGF 259 Query: 177 LLYMLVEIILFCLLLYFY--KEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGN 234 +++ ++ +++ CL+L F NI++ +++ +++G+ +V VK + + QG Sbjct: 260 IVFAVL-LLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFSVAAVKGLGITIKNFFQGL 318 Query: 235 LQLDYPIFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLD 294 + +P+ Y++ + + + Q FL++A ++++SL+ + Y+ TT+ +T+ I + + Sbjct: 319 PVVRHPLPYILSLILALSLSTQVNFLNRALDIFNTSLVFPIYYVFFTTVVVTSSIILFKE 378 Query: 295 FIGEDVLHICMFALGCLIAFLGVFLI 320 + + I G + LGVF++ Sbjct: 379 WYSMSAVDIAGTLSGFVTIILGVFML 404 >gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2 isoform a [Homo sapiens] Length = 360 Score = 120 bits (302), Expect = 2e-27 Identities = 88/342 (25%), Positives = 167/342 (48%), Gaps = 25/342 (7%) Query: 35 IGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWLGLFLMLLGEL 88 IG LA+ + + + L+K +RLA RA Y K WW GL M GE+ Sbjct: 12 IGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEV 71 Query: 89 GVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGT 148 FA+YAFAP +L+ PL A+SV+ SAI+ F+ E R + +GC L+++G+ Sbjct: 72 ANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNE--------RLNLHGKIGCLLSILGS 123 Query: 149 YLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNA-NNIVVILL 207 ++V AP E T ++ L F+++ + +I+ +L++ ++ NI+V + Sbjct: 124 TVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYIT 183 Query: 208 LVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMY 267 + +++G+ +V VK + + G L +P+ +++ + ++ Q +L++A ++ Sbjct: 184 ICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIF 243 Query: 268 DSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLITRNRKKP 327 ++S++ + Y+ TT +T AI + ++ V + G +G+FL+ + K Sbjct: 244 NTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLL--HAFKD 301 Query: 328 IPFEPYISMDAMPGMQNMHDKGMTVQPELKASFSYGALENND 369 + F S+ ++P +K M S Y L NN+ Sbjct: 302 VSF----SLASLPVSFRKDEKAMNG----NLSNMYEVLNNNE 335 >gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2 isoform a [Homo sapiens] Length = 360 Score = 120 bits (302), Expect = 2e-27 Identities = 88/342 (25%), Positives = 167/342 (48%), Gaps = 25/342 (7%) Query: 35 IGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWLGLFLMLLGEL 88 IG LA+ + + + L+K +RLA RA Y K WW GL M GE+ Sbjct: 12 IGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEV 71 Query: 89 GVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGT 148 FA+YAFAP +L+ PL A+SV+ SAI+ F+ E R + +GC L+++G+ Sbjct: 72 ANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNE--------RLNLHGKIGCLLSILGS 123 Query: 149 YLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNA-NNIVVILL 207 ++V AP E T ++ L F+++ + +I+ +L++ ++ NI+V + Sbjct: 124 TVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYIT 183 Query: 208 LVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMY 267 + +++G+ +V VK + + G L +P+ +++ + ++ Q +L++A ++ Sbjct: 184 ICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIF 243 Query: 268 DSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLITRNRKKP 327 ++S++ + Y+ TT +T AI + ++ V + G +G+FL+ + K Sbjct: 244 NTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLL--HAFKD 301 Query: 328 IPFEPYISMDAMPGMQNMHDKGMTVQPELKASFSYGALENND 369 + F S+ ++P +K M S Y L NN+ Sbjct: 302 VSF----SLASLPVSFRKDEKAMNG----NLSNMYEVLNNNE 335 >gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2 isoform a [Homo sapiens] Length = 360 Score = 120 bits (302), Expect = 2e-27 Identities = 88/342 (25%), Positives = 167/342 (48%), Gaps = 25/342 (7%) Query: 35 IGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWLGLFLMLLGEL 88 IG LA+ + + + L+K +RLA RA Y K WW GL M GE+ Sbjct: 12 IGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEV 71 Query: 89 GVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGT 148 FA+YAFAP +L+ PL A+SV+ SAI+ F+ E R + +GC L+++G+ Sbjct: 72 ANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNE--------RLNLHGKIGCLLSILGS 123 Query: 149 YLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNA-NNIVVILL 207 ++V AP E T ++ L F+++ + +I+ +L++ ++ NI+V + Sbjct: 124 TVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYIT 183 Query: 208 LVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMY 267 + +++G+ +V VK + + G L +P+ +++ + ++ Q +L++A ++ Sbjct: 184 ICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIF 243 Query: 268 DSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLITRNRKKP 327 ++S++ + Y+ TT +T AI + ++ V + G +G+FL+ + K Sbjct: 244 NTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLL--HAFKD 301 Query: 328 IPFEPYISMDAMPGMQNMHDKGMTVQPELKASFSYGALENND 369 + F S+ ++P +K M S Y L NN+ Sbjct: 302 VSF----SLASLPVSFRKDEKAMNG----NLSNMYEVLNNNE 335 >gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1 isoform 1 [Homo sapiens] Length = 329 Score = 107 bits (267), Expect = 2e-23 Identities = 71/289 (24%), Positives = 138/289 (47%), Gaps = 13/289 (4%) Query: 35 IGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASY 94 +G +A+ LV LQK +R + +Y WW G M +G++G F +Y Sbjct: 30 LGLGVAVVSSLVNGSTFVLQKKGIVR--AKRRGTSYLTDIVWWAGTIAMAVGQIGNFLAY 87 Query: 95 AFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTF 154 P L+ PL A+ V +I+ +KEK +L +GC L+ G+ +L+ Sbjct: 88 TAVPTVLVTPLGALGVPFGSILASYLLKEKLN--------ILGKLGCLLSCAGSVVLIIH 139 Query: 155 APNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNA-NNIVVILLLVALLG 213 +P S T + L + F+ Y+ + +++ LL+++ + NI+V + + +LLG Sbjct: 140 SPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISICSLLG 199 Query: 214 SMTVVTVKAV--AGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMYDSSL 271 S TV + K + A +L + Q + V+ + + + Q ++++A + +DSS+ Sbjct: 200 SFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECFDSSV 259 Query: 272 IASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLI 320 ++ Y++ TT+ + A AI + ++ ++ A G +G+ LI Sbjct: 260 FGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLI 308 >gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2 isoform b [Homo sapiens] Length = 341 Score = 102 bits (255), Expect = 5e-22 Identities = 81/336 (24%), Positives = 161/336 (47%), Gaps = 32/336 (9%) Query: 35 IGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASY 94 IG LA+ + + + L+K +RLA RA + GE+ FA+Y Sbjct: 12 IGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRA-------------VGAGEVANFAAY 58 Query: 95 AFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTF 154 AFAP +L+ PL A+SV+ SAI+ F+ E R + +GC L+++G+ ++V Sbjct: 59 AFAPATLVTPLGALSVLVSAILSSYFLNE--------RLNLHGKIGCLLSILGSTVMVIH 110 Query: 155 APNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNAN-NIVVILLLVALLG 213 AP E T ++ L F+++ + +I+ +L++ ++ NI+V + + +++G Sbjct: 111 APKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIG 170 Query: 214 SMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMYDSSLIA 273 + +V VK + + G L +P+ +++ + ++ Q +L++A ++++S++ Sbjct: 171 AFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVT 230 Query: 274 SVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLITRNRKKPIPFEPY 333 + Y+ TT +T AI + ++ V + G +G+FL+ + K + F Sbjct: 231 PIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLL--HAFKDVSF--- 285 Query: 334 ISMDAMPGMQNMHDKGMTVQPELKASFSYGALENND 369 S+ ++P +K M S Y L NN+ Sbjct: 286 -SLASLPVSFRKDEKAMNG----NLSNMYEVLNNNE 316 >gi|214010179 non-imprinted in Prader-Willi/Angelman syndrome 1 isoform 2 [Homo sapiens] Length = 254 Score = 94.0 bits (232), Expect = 2e-19 Identities = 59/241 (24%), Positives = 120/241 (49%), Gaps = 11/241 (4%) Query: 83 MLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCG 142 M +G++G F +Y P L+ PL A+ V +I+ +KEK +L +GC Sbjct: 1 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLN--------ILGKLGCL 52 Query: 143 LAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNA-NN 201 L+ G+ +L+ +P S T + L + F+ Y+ + +++ LL+++ + N Sbjct: 53 LSCAGSVVLIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTN 112 Query: 202 IVVILLLVALLGSMTVVTVKAV--AGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAF 259 I+V + + +LLGS TV + K + A +L + Q + V+ + + + Q + Sbjct: 113 IMVYISICSLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRY 172 Query: 260 LSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFL 319 +++A + +DSS+ ++ Y++ TT+ + A AI + ++ ++ A G +G+ L Sbjct: 173 INKALECFDSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVL 232 Query: 320 I 320 I Sbjct: 233 I 233 >gi|238859647 G protein-coupled receptor 128 [Homo sapiens] Length = 797 Score = 32.3 bits (72), Expect = 0.79 Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 7/68 (10%) Query: 135 VLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFY 194 +LS VGC L+V G L V F ++ V + V+W L+ + + +++F LL F Sbjct: 436 ILSNVGCALSVTGLALTVIF------QIVTRKVRKTSVTW-VLVNLCISMLIFNLLFVFG 488 Query: 195 KEKNANNI 202 E + N+ Sbjct: 489 IENSNKNL 496 >gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B [Homo sapiens] Length = 250 Score = 31.6 bits (70), Expect = 1.3 Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 6/82 (7%) Query: 76 WWLGLFLMLLGELGVFAS---YAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLR 132 +W GL+ ++ G L V A Y++ LS + L+ VS I SA+ I+FI + P + Sbjct: 109 FWGGLWFIISGSLSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDLSIPHPYAY 168 Query: 133 RYVLSF---VGCGLAVVGTYLL 151 + V G+A+ G L+ Sbjct: 169 PDYYPYAWGVNPGMAISGVLLV 190 >gi|116517313 mannose-P-dolichol utilization defect 1 [Homo sapiens] Length = 247 Score = 30.4 bits (67), Expect = 3.0 Identities = 15/55 (27%), Positives = 31/55 (56%), Gaps = 7/55 (12%) Query: 173 SWPFLLYMLVEIILFCLLLYFYKEKNANNI-------VVILLLVALLGSMTVVTV 220 SW L+++++ I C L+ Y+ + + +V+L+L++ L +TVVT+ Sbjct: 102 SWGEALFLMLQTITICFLVMHYRGQTVKGVAFLACYGLVLLVLLSPLTPLTVVTL 156 >gi|153945846 inositol 1,4,5-triphosphate receptor, type 3 [Homo sapiens] Length = 2671 Score = 30.0 bits (66), Expect = 3.9 Identities = 40/165 (24%), Positives = 65/165 (39%), Gaps = 22/165 (13%) Query: 130 FLRRYVL-SFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFC 188 F RR L + LAV ++ F P TG ++ P + + +I F Sbjct: 2197 FSRRMTLWGSISFNLAVFINIIIAFFYPYMEGASTG------VLDSPLISLLFWILICFS 2250 Query: 189 LLLYFYKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPI-FYVMFV 247 + F K + ++V L+L ++ T L+I G L L I F V FV Sbjct: 2251 IAALFTKRYSIRPLIVALILRSIYYLGIGPT---------LNILGALNLTNKIVFVVSFV 2301 Query: 248 CMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFY 292 T + + + D + VGYIL++ + + A +FY Sbjct: 2302 GNRGTFIR-----GYKAMVMDMEFLYHVGYILTSVLGLFAHELFY 2341 >gi|223029454 solute carrier family 46, member 2 [Homo sapiens] Length = 475 Score = 29.3 bits (64), Expect = 6.7 Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 10/100 (10%) Query: 241 IFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITA-------GAIFYL 293 +FY+ M+ + S S++ S V IL ++A+T I+ L Sbjct: 373 MFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQL 432 Query: 294 DFIGEDVLHICMFALGCLIAFLGVFLITRNRKKPIPFEPY 333 D+ FAL ++FL + I+ K +P PY Sbjct: 433 TM---DMFVGSCFALSSFLSFLAIIPISIVAYKQVPLSPY 469 >gi|21389515 ring finger protein 145 [Homo sapiens] Length = 691 Score = 29.3 bits (64), Expect = 6.7 Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 7/104 (6%) Query: 217 VVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMYDSS-----L 271 +V V V G+L L + QL P+ +++F +V A+ ++ S Q Sbjct: 233 LVQVVEVYGLLALGMSLWNQLVVPVLFMVF-WLVLFALQIYSYFSTRDQPASRERLLFLF 291 Query: 272 IASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFL 315 + S+ ST ++ G +F + F+ VL +C F L AF+ Sbjct: 292 LTSIAECCSTPYSLL-GLVFTVSFVALGVLTLCKFYLQGYRAFM 334 >gi|26638655 potassium voltage-gated channel KQT-like protein 4 isoform b [Homo sapiens] Length = 641 Score = 28.9 bits (63), Expect = 8.7 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Query: 91 FASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYL 150 FA F + IV +++V+VIA+ G IF + FL+ +L V GT+ Sbjct: 169 FARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQ--ILRMVRMDRR-GGTWK 225 Query: 151 LVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNANNIVVILLLVA 210 L+ +H K + +W Y+ +++F L + EK+AN+ Sbjct: 226 LLGSVVYAHSK-------ELITAW----YIGFLVLIFASFLVYLAEKDANSDFSSYADSL 274 Query: 211 LLGSMTVVTV 220 G++T+ T+ Sbjct: 275 WWGTITLTTI 284 >gi|26638653 potassium voltage-gated channel KQT-like protein 4 isoform a [Homo sapiens] Length = 695 Score = 28.9 bits (63), Expect = 8.7 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Query: 91 FASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYL 150 FA F + IV +++V+VIA+ G IF + FL+ +L V GT+ Sbjct: 169 FARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQ--ILRMVRMDRR-GGTWK 225 Query: 151 LVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNANNIVVILLLVA 210 L+ +H K + +W Y+ +++F L + EK+AN+ Sbjct: 226 LLGSVVYAHSK-------ELITAW----YIGFLVLIFASFLVYLAEKDANSDFSSYADSL 274 Query: 211 LLGSMTVVTV 220 G++T+ T+ Sbjct: 275 WWGTITLTTI 284 >gi|4885441 solute carrier family 17 (sodium phosphate), member 4 [Homo sapiens] Length = 497 Score = 28.9 bits (63), Expect = 8.7 Identities = 62/316 (19%), Positives = 125/316 (39%), Gaps = 58/316 (18%) Query: 77 WLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAII--GIIFIKEKWKPKDFLRRY 134 +L LF+ L GV +L++ L V IA ++ G I KW P L R Sbjct: 150 FLTLFIPLAANAGV---------ALLIVLRIVQGIAQVMVLTGQYSIWVKWAPP--LERS 198 Query: 135 VLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYF- 193 L+ + +++G++++ + + + WP++ Y+ I C L+F Sbjct: 199 QLTTIAGSGSMLGSFIV----------LLAGGLLCQTIGWPYVFYIFGGIGCACCPLWFP 248 Query: 194 ----------YKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVL-SIQGNLQLDYPIF 242 + +V L + ++A+ L L +I + +Y +F Sbjct: 249 LIYDDPVNHPFISAGEKRYIVCSLAQQDCSPGWSLPIRAMIKSLPLWAILVSYFCEYWLF 308 Query: 243 YVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLH 302 Y + M T Y ++ L + + DS +++++ +++ I G + DF+ + Sbjct: 309 YTI---MAYTPTYISSVLQ--ANLRDSGILSALPFVVGCICIILGGLL--ADFLLSRKI- 360 Query: 303 ICMFALGCLIAFLGVFLITRNRKKPIPFEPYISMDAMPGMQNMHDKGMTVQPELKASFSY 362 + + + L +GV P + + ++P +++ H MT A S+ Sbjct: 361 LRLITIRKLFTAIGVLF------------PSVILVSLPWVRSSHSMTMTFLVLSSAISSF 408 Query: 363 ---GALENNDNISEIY 375 GAL N +I+ Y Sbjct: 409 CESGALVNFLDIAPRY 424 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.325 0.139 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,168,133 Number of Sequences: 37866 Number of extensions: 507595 Number of successful extensions: 1608 Number of sequences better than 10.0: 19 Number of HSP's better than 10.0 without gapping: 10 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 1568 Number of HSP's gapped (non-prelim): 22 length of query: 406 length of database: 18,247,518 effective HSP length: 105 effective length of query: 301 effective length of database: 14,271,588 effective search space: 4295747988 effective search space used: 4295747988 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.