Guide to the Human Genome
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Search of human proteins with 10092687

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10092687 NIPA-like domain containing 3 [Homo sapiens]
         (406 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10092687 NIPA-like domain containing 3 [Homo sapiens]              797   0.0  
gi|13376097 NIPA-like domain containing 2 [Homo sapiens]              310   2e-84
gi|46409302 NIPA-like domain containing 1 [Homo sapiens]              125   7e-29
gi|149944536 ichthyin protein [Homo sapiens]                          125   9e-29
gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2 is...   120   2e-27
gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2 is...   120   2e-27
gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2 is...   120   2e-27
gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1 is...   107   2e-23
gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2 is...   102   5e-22
gi|214010179 non-imprinted in Prader-Willi/Angelman syndrome 1 i...    94   2e-19
gi|238859647 G protein-coupled receptor 128 [Homo sapiens]             32   0.79 
gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B ...    32   1.3  
gi|116517313 mannose-P-dolichol utilization defect 1 [Homo sapiens]    30   3.0  
gi|153945846 inositol 1,4,5-triphosphate receptor, type 3 [Homo ...    30   3.9  
gi|223029454 solute carrier family 46, member 2 [Homo sapiens]         29   6.7  
gi|21389515 ring finger protein 145 [Homo sapiens]                     29   6.7  
gi|26638655 potassium voltage-gated channel KQT-like protein 4 i...    29   8.7  
gi|26638653 potassium voltage-gated channel KQT-like protein 4 i...    29   8.7  
gi|4885441 solute carrier family 17 (sodium phosphate), member 4...    29   8.7  

>gi|10092687 NIPA-like domain containing 3 [Homo sapiens]
          Length = 406

 Score =  797 bits (2058), Expect = 0.0
 Identities = 406/406 (100%), Positives = 406/406 (100%)

Query: 1   MDGSHSAALKLQQLPPTSSSSAVSEASFSYKENLIGALLAIFGHLVVSIALNLQKYCHIR 60
           MDGSHSAALKLQQLPPTSSSSAVSEASFSYKENLIGALLAIFGHLVVSIALNLQKYCHIR
Sbjct: 1   MDGSHSAALKLQQLPPTSSSSAVSEASFSYKENLIGALLAIFGHLVVSIALNLQKYCHIR 60

Query: 61  LAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIF 120
           LAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIF
Sbjct: 61  LAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIF 120

Query: 121 IKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYM 180
           IKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYM
Sbjct: 121 IKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYM 180

Query: 181 LVEIILFCLLLYFYKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYP 240
           LVEIILFCLLLYFYKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYP
Sbjct: 181 LVEIILFCLLLYFYKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYP 240

Query: 241 IFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDV 300
           IFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDV
Sbjct: 241 IFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDV 300

Query: 301 LHICMFALGCLIAFLGVFLITRNRKKPIPFEPYISMDAMPGMQNMHDKGMTVQPELKASF 360
           LHICMFALGCLIAFLGVFLITRNRKKPIPFEPYISMDAMPGMQNMHDKGMTVQPELKASF
Sbjct: 301 LHICMFALGCLIAFLGVFLITRNRKKPIPFEPYISMDAMPGMQNMHDKGMTVQPELKASF 360

Query: 361 SYGALENNDNISEIYAPATLPVMQEEHGSRSASGVPYRVLEHTKKE 406
           SYGALENNDNISEIYAPATLPVMQEEHGSRSASGVPYRVLEHTKKE
Sbjct: 361 SYGALENNDNISEIYAPATLPVMQEEHGSRSASGVPYRVLEHTKKE 406


>gi|13376097 NIPA-like domain containing 2 [Homo sapiens]
          Length = 368

 Score =  310 bits (793), Expect = 2e-84
 Identities = 158/343 (46%), Positives = 225/343 (65%), Gaps = 14/343 (4%)

Query: 4   SHSAALKLQQLPPTSSSSAVSEASFS---YKEN---LIGALLAIFGHLVVSIALNLQKYC 57
           S SAAL    L  T  +      S S   Y+ N   L G LLAI G+LV+SI+LN+QKY 
Sbjct: 12  SASAALDELSLNFTYGAPGAGNGSLSGDWYRRNQIHLFGVLLAILGNLVISISLNIQKYS 71

Query: 58  HIRLAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIG 117
           H++LA  + PR YFK+  WW G+ LM +GE G FA+Y FAP++LI PL  VSV  SAII 
Sbjct: 72  HLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYGFAPITLIAPLGCVSVTGSAIIS 131

Query: 118 IIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFL 177
           + F+K+  +  D L        G  LA  GTYLLV FAPN  + ++   V  +LV W FL
Sbjct: 132 VTFLKDNLRASDLL--------GTTLAFAGTYLLVNFAPNITQAISARTVQYYLVGWQFL 183

Query: 178 LYMLVEIILFCLLLYFYKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQL 237
           +Y+++EI++FC+LLYFYK K   ++V++L LVA+L S+TV++VKAV+GM+  S+   +QL
Sbjct: 184 IYVILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISVKAVSGMITFSVMDKMQL 243

Query: 238 DYPIFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIG 297
            YPIFY+MF+ M+A+ V+Q  FL+QA+++Y+++ +  V +I  T  AI AG IFY +F+G
Sbjct: 244 TYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAGIIFYQEFLG 303

Query: 298 EDVLHICMFALGCLIAFLGVFLITRNRKKPIPFEPYISMDAMP 340
              L + ++  GC ++FLGVFL+TRNR+K    + YI    +P
Sbjct: 304 APFLTVFIYLFGCFLSFLGVFLVTRNREKEHLQQSYIDFGNIP 346


>gi|46409302 NIPA-like domain containing 1 [Homo sapiens]
          Length = 410

 Score =  125 bits (314), Expect = 7e-29
 Identities = 78/293 (26%), Positives = 148/293 (50%), Gaps = 15/293 (5%)

Query: 35  IGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWLGLFLMLLGEL 88
           +G +LA+   + +  +  L+K   ++LA     RA      Y K   WW+GL  M  GE 
Sbjct: 70  VGLVLAVSSSIFIGSSFILKKKGLLQLASKGFTRAGQGGHSYLKEWLWWVGLLSMGAGEA 129

Query: 89  GVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGT 148
             FA+YAFAP +L+ PL A+SV+ SAI+   F+ E           +   +GC L+++G+
Sbjct: 130 ANFAAYAFAPATLVTPLGALSVLISAILSSYFLNEHLN--------IHGKIGCILSILGS 181

Query: 149 YLLVTFAPNSHEKMTGENVTRHLVSWPFLLY-MLVEIILFCLLLYFYKEKNANNIVVILL 207
            ++V  AP   E  +   +   L    F+ + +++ +I   L+L    +K   NI+V + 
Sbjct: 182 TVMVIHAPQEEEVTSLHEMEMKLRDPGFISFAVIITVISLVLILIVAPKKGQTNILVYIS 241

Query: 208 LVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMY 267
           + +L+G+ +V +VK +   +   I+      +P+ +V+   +V +   Q  +L++A   +
Sbjct: 242 ICSLIGAFSVSSVKGLGIAIKELIEWKPVYKHPLVFVLLAVLVLSVTTQINYLNKALDTF 301

Query: 268 DSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLI 320
           ++SL+  + Y+  T++ +T  AI + ++ G     I     G     +G+FL+
Sbjct: 302 NTSLVTPIYYVFFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIFLL 354


>gi|149944536 ichthyin protein [Homo sapiens]
          Length = 466

 Score =  125 bits (313), Expect = 9e-29
 Identities = 83/326 (25%), Positives = 162/326 (49%), Gaps = 25/326 (7%)

Query: 11  LQQLPPTSSSSAVSEASF-SYKENL-------IGALLAIFGHLVVSIALNLQKYCHIRLA 62
           L Q+    S    S A+F S++E +       IG  LA     ++  ++ L+K   +RL 
Sbjct: 88  LCQIVNDLSPEVPSNATFHSWQERIRQNYGFYIGLGLAFLSSFLIGSSVILKKKGLLRLV 147

Query: 63  GSKDPRA------YFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAII 116
            +   RA      Y K   WW G   M  GE+  F +YAFAP +++ PL A+SV+ SAI+
Sbjct: 148 ATGATRAVDGGFGYLKDAMWWAGFLTMAAGEVANFGAYAFAPATVVTPLGALSVLISAIL 207

Query: 117 GIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPF 176
              F++E           +L  +GC + V G+ ++V  AP   +  T   +   +    F
Sbjct: 208 SSYFLRESLN--------LLGKLGCVICVAGSTVMVIHAPEEEKVTTIMEMASKMKDTGF 259

Query: 177 LLYMLVEIILFCLLLYFY--KEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGN 234
           +++ ++ +++ CL+L F         NI++ +++ +++G+ +V  VK +   +    QG 
Sbjct: 260 IVFAVL-LLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFSVAAVKGLGITIKNFFQGL 318

Query: 235 LQLDYPIFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLD 294
             + +P+ Y++ + +  +   Q  FL++A  ++++SL+  + Y+  TT+ +T+  I + +
Sbjct: 319 PVVRHPLPYILSLILALSLSTQVNFLNRALDIFNTSLVFPIYYVFFTTVVVTSSIILFKE 378

Query: 295 FIGEDVLHICMFALGCLIAFLGVFLI 320
           +     + I     G +   LGVF++
Sbjct: 379 WYSMSAVDIAGTLSGFVTIILGVFML 404


>gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform a [Homo sapiens]
          Length = 360

 Score =  120 bits (302), Expect = 2e-27
 Identities = 88/342 (25%), Positives = 167/342 (48%), Gaps = 25/342 (7%)

Query: 35  IGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWLGLFLMLLGEL 88
           IG  LA+   + +  +  L+K   +RLA     RA      Y K   WW GL  M  GE+
Sbjct: 12  IGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEV 71

Query: 89  GVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGT 148
             FA+YAFAP +L+ PL A+SV+ SAI+   F+ E        R  +   +GC L+++G+
Sbjct: 72  ANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNE--------RLNLHGKIGCLLSILGS 123

Query: 149 YLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNA-NNIVVILL 207
            ++V  AP   E  T   ++  L    F+++  + +I+  +L++    ++   NI+V + 
Sbjct: 124 TVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYIT 183

Query: 208 LVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMY 267
           + +++G+ +V  VK +   +     G   L +P+ +++ + ++     Q  +L++A  ++
Sbjct: 184 ICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIF 243

Query: 268 DSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLITRNRKKP 327
           ++S++  + Y+  TT  +T  AI + ++    V  +     G     +G+FL+  +  K 
Sbjct: 244 NTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLL--HAFKD 301

Query: 328 IPFEPYISMDAMPGMQNMHDKGMTVQPELKASFSYGALENND 369
           + F    S+ ++P      +K M        S  Y  L NN+
Sbjct: 302 VSF----SLASLPVSFRKDEKAMNG----NLSNMYEVLNNNE 335


>gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform a [Homo sapiens]
          Length = 360

 Score =  120 bits (302), Expect = 2e-27
 Identities = 88/342 (25%), Positives = 167/342 (48%), Gaps = 25/342 (7%)

Query: 35  IGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWLGLFLMLLGEL 88
           IG  LA+   + +  +  L+K   +RLA     RA      Y K   WW GL  M  GE+
Sbjct: 12  IGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEV 71

Query: 89  GVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGT 148
             FA+YAFAP +L+ PL A+SV+ SAI+   F+ E        R  +   +GC L+++G+
Sbjct: 72  ANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNE--------RLNLHGKIGCLLSILGS 123

Query: 149 YLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNA-NNIVVILL 207
            ++V  AP   E  T   ++  L    F+++  + +I+  +L++    ++   NI+V + 
Sbjct: 124 TVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYIT 183

Query: 208 LVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMY 267
           + +++G+ +V  VK +   +     G   L +P+ +++ + ++     Q  +L++A  ++
Sbjct: 184 ICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIF 243

Query: 268 DSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLITRNRKKP 327
           ++S++  + Y+  TT  +T  AI + ++    V  +     G     +G+FL+  +  K 
Sbjct: 244 NTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLL--HAFKD 301

Query: 328 IPFEPYISMDAMPGMQNMHDKGMTVQPELKASFSYGALENND 369
           + F    S+ ++P      +K M        S  Y  L NN+
Sbjct: 302 VSF----SLASLPVSFRKDEKAMNG----NLSNMYEVLNNNE 335


>gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform a [Homo sapiens]
          Length = 360

 Score =  120 bits (302), Expect = 2e-27
 Identities = 88/342 (25%), Positives = 167/342 (48%), Gaps = 25/342 (7%)

Query: 35  IGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWLGLFLMLLGEL 88
           IG  LA+   + +  +  L+K   +RLA     RA      Y K   WW GL  M  GE+
Sbjct: 12  IGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEV 71

Query: 89  GVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGT 148
             FA+YAFAP +L+ PL A+SV+ SAI+   F+ E        R  +   +GC L+++G+
Sbjct: 72  ANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNE--------RLNLHGKIGCLLSILGS 123

Query: 149 YLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNA-NNIVVILL 207
            ++V  AP   E  T   ++  L    F+++  + +I+  +L++    ++   NI+V + 
Sbjct: 124 TVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYIT 183

Query: 208 LVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMY 267
           + +++G+ +V  VK +   +     G   L +P+ +++ + ++     Q  +L++A  ++
Sbjct: 184 ICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIF 243

Query: 268 DSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLITRNRKKP 327
           ++S++  + Y+  TT  +T  AI + ++    V  +     G     +G+FL+  +  K 
Sbjct: 244 NTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLL--HAFKD 301

Query: 328 IPFEPYISMDAMPGMQNMHDKGMTVQPELKASFSYGALENND 369
           + F    S+ ++P      +K M        S  Y  L NN+
Sbjct: 302 VSF----SLASLPVSFRKDEKAMNG----NLSNMYEVLNNNE 335


>gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1
           isoform 1 [Homo sapiens]
          Length = 329

 Score =  107 bits (267), Expect = 2e-23
 Identities = 71/289 (24%), Positives = 138/289 (47%), Gaps = 13/289 (4%)

Query: 35  IGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASY 94
           +G  +A+   LV      LQK   +R    +   +Y     WW G   M +G++G F +Y
Sbjct: 30  LGLGVAVVSSLVNGSTFVLQKKGIVR--AKRRGTSYLTDIVWWAGTIAMAVGQIGNFLAY 87

Query: 95  AFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTF 154
              P  L+ PL A+ V   +I+    +KEK          +L  +GC L+  G+ +L+  
Sbjct: 88  TAVPTVLVTPLGALGVPFGSILASYLLKEKLN--------ILGKLGCLLSCAGSVVLIIH 139

Query: 155 APNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNA-NNIVVILLLVALLG 213
           +P S    T   +   L +  F+ Y+ + +++  LL+++    +   NI+V + + +LLG
Sbjct: 140 SPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISICSLLG 199

Query: 214 SMTVVTVKAV--AGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMYDSSL 271
           S TV + K +  A   +L    + Q    +  V+   +  + + Q  ++++A + +DSS+
Sbjct: 200 SFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECFDSSV 259

Query: 272 IASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLI 320
             ++ Y++ TT+ + A AI + ++    ++     A G     +G+ LI
Sbjct: 260 FGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLI 308


>gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform b [Homo sapiens]
          Length = 341

 Score =  102 bits (255), Expect = 5e-22
 Identities = 81/336 (24%), Positives = 161/336 (47%), Gaps = 32/336 (9%)

Query: 35  IGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASY 94
           IG  LA+   + +  +  L+K   +RLA     RA             +  GE+  FA+Y
Sbjct: 12  IGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRA-------------VGAGEVANFAAY 58

Query: 95  AFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTF 154
           AFAP +L+ PL A+SV+ SAI+   F+ E        R  +   +GC L+++G+ ++V  
Sbjct: 59  AFAPATLVTPLGALSVLVSAILSSYFLNE--------RLNLHGKIGCLLSILGSTVMVIH 110

Query: 155 APNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNAN-NIVVILLLVALLG 213
           AP   E  T   ++  L    F+++  + +I+  +L++    ++   NI+V + + +++G
Sbjct: 111 APKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIG 170

Query: 214 SMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMYDSSLIA 273
           + +V  VK +   +     G   L +P+ +++ + ++     Q  +L++A  ++++S++ 
Sbjct: 171 AFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVT 230

Query: 274 SVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLITRNRKKPIPFEPY 333
            + Y+  TT  +T  AI + ++    V  +     G     +G+FL+  +  K + F   
Sbjct: 231 PIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLL--HAFKDVSF--- 285

Query: 334 ISMDAMPGMQNMHDKGMTVQPELKASFSYGALENND 369
            S+ ++P      +K M        S  Y  L NN+
Sbjct: 286 -SLASLPVSFRKDEKAMNG----NLSNMYEVLNNNE 316


>gi|214010179 non-imprinted in Prader-Willi/Angelman syndrome 1
           isoform 2 [Homo sapiens]
          Length = 254

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 59/241 (24%), Positives = 120/241 (49%), Gaps = 11/241 (4%)

Query: 83  MLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCG 142
           M +G++G F +Y   P  L+ PL A+ V   +I+    +KEK          +L  +GC 
Sbjct: 1   MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLN--------ILGKLGCL 52

Query: 143 LAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNA-NN 201
           L+  G+ +L+  +P S    T   +   L +  F+ Y+ + +++  LL+++    +   N
Sbjct: 53  LSCAGSVVLIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTN 112

Query: 202 IVVILLLVALLGSMTVVTVKAV--AGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAF 259
           I+V + + +LLGS TV + K +  A   +L    + Q    +  V+   +  + + Q  +
Sbjct: 113 IMVYISICSLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRY 172

Query: 260 LSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFL 319
           +++A + +DSS+  ++ Y++ TT+ + A AI + ++    ++     A G     +G+ L
Sbjct: 173 INKALECFDSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVL 232

Query: 320 I 320
           I
Sbjct: 233 I 233


>gi|238859647 G protein-coupled receptor 128 [Homo sapiens]
          Length = 797

 Score = 32.3 bits (72), Expect = 0.79
 Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 7/68 (10%)

Query: 135 VLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFY 194
           +LS VGC L+V G  L V F      ++    V +  V+W  L+ + + +++F LL  F 
Sbjct: 436 ILSNVGCALSVTGLALTVIF------QIVTRKVRKTSVTW-VLVNLCISMLIFNLLFVFG 488

Query: 195 KEKNANNI 202
            E +  N+
Sbjct: 489 IENSNKNL 496


>gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B
           [Homo sapiens]
          Length = 250

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 6/82 (7%)

Query: 76  WWLGLFLMLLGELGVFAS---YAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLR 132
           +W GL+ ++ G L V A    Y++  LS  + L+ VS I SA+  I+FI +   P  +  
Sbjct: 109 FWGGLWFIISGSLSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDLSIPHPYAY 168

Query: 133 RYVLSF---VGCGLAVVGTYLL 151
                +   V  G+A+ G  L+
Sbjct: 169 PDYYPYAWGVNPGMAISGVLLV 190


>gi|116517313 mannose-P-dolichol utilization defect 1 [Homo sapiens]
          Length = 247

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 15/55 (27%), Positives = 31/55 (56%), Gaps = 7/55 (12%)

Query: 173 SWPFLLYMLVEIILFCLLLYFYKEKNANNI-------VVILLLVALLGSMTVVTV 220
           SW   L+++++ I  C L+  Y+ +    +       +V+L+L++ L  +TVVT+
Sbjct: 102 SWGEALFLMLQTITICFLVMHYRGQTVKGVAFLACYGLVLLVLLSPLTPLTVVTL 156


>gi|153945846 inositol 1,4,5-triphosphate receptor, type 3 [Homo
            sapiens]
          Length = 2671

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 40/165 (24%), Positives = 65/165 (39%), Gaps = 22/165 (13%)

Query: 130  FLRRYVL-SFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFC 188
            F RR  L   +   LAV    ++  F P      TG      ++  P +  +   +I F 
Sbjct: 2197 FSRRMTLWGSISFNLAVFINIIIAFFYPYMEGASTG------VLDSPLISLLFWILICFS 2250

Query: 189  LLLYFYKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPI-FYVMFV 247
            +   F K  +   ++V L+L ++       T         L+I G L L   I F V FV
Sbjct: 2251 IAALFTKRYSIRPLIVALILRSIYYLGIGPT---------LNILGALNLTNKIVFVVSFV 2301

Query: 248  CMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFY 292
                T +         + + D   +  VGYIL++ + + A  +FY
Sbjct: 2302 GNRGTFIR-----GYKAMVMDMEFLYHVGYILTSVLGLFAHELFY 2341


>gi|223029454 solute carrier family 46, member 2 [Homo sapiens]
          Length = 475

 Score = 29.3 bits (64), Expect = 6.7
 Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 10/100 (10%)

Query: 241 IFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITA-------GAIFYL 293
           +FY+    M+   +      S  S++   S    V  IL  ++A+T          I+ L
Sbjct: 373 MFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQL 432

Query: 294 DFIGEDVLHICMFALGCLIAFLGVFLITRNRKKPIPFEPY 333
                D+     FAL   ++FL +  I+    K +P  PY
Sbjct: 433 TM---DMFVGSCFALSSFLSFLAIIPISIVAYKQVPLSPY 469


>gi|21389515 ring finger protein 145 [Homo sapiens]
          Length = 691

 Score = 29.3 bits (64), Expect = 6.7
 Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 7/104 (6%)

Query: 217 VVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMYDSS-----L 271
           +V V  V G+L L +    QL  P+ +++F  +V  A+   ++ S   Q           
Sbjct: 233 LVQVVEVYGLLALGMSLWNQLVVPVLFMVF-WLVLFALQIYSYFSTRDQPASRERLLFLF 291

Query: 272 IASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFL 315
           + S+    ST  ++  G +F + F+   VL +C F L    AF+
Sbjct: 292 LTSIAECCSTPYSLL-GLVFTVSFVALGVLTLCKFYLQGYRAFM 334


>gi|26638655 potassium voltage-gated channel KQT-like protein 4
           isoform b [Homo sapiens]
          Length = 641

 Score = 28.9 bits (63), Expect = 8.7
 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 14/130 (10%)

Query: 91  FASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYL 150
           FA   F  +  IV +++V+VIA+   G IF     +   FL+  +L  V       GT+ 
Sbjct: 169 FARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQ--ILRMVRMDRR-GGTWK 225

Query: 151 LVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNANNIVVILLLVA 210
           L+     +H K         + +W    Y+   +++F   L +  EK+AN+         
Sbjct: 226 LLGSVVYAHSK-------ELITAW----YIGFLVLIFASFLVYLAEKDANSDFSSYADSL 274

Query: 211 LLGSMTVVTV 220
             G++T+ T+
Sbjct: 275 WWGTITLTTI 284


>gi|26638653 potassium voltage-gated channel KQT-like protein 4
           isoform a [Homo sapiens]
          Length = 695

 Score = 28.9 bits (63), Expect = 8.7
 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 14/130 (10%)

Query: 91  FASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYL 150
           FA   F  +  IV +++V+VIA+   G IF     +   FL+  +L  V       GT+ 
Sbjct: 169 FARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQ--ILRMVRMDRR-GGTWK 225

Query: 151 LVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNANNIVVILLLVA 210
           L+     +H K         + +W    Y+   +++F   L +  EK+AN+         
Sbjct: 226 LLGSVVYAHSK-------ELITAW----YIGFLVLIFASFLVYLAEKDANSDFSSYADSL 274

Query: 211 LLGSMTVVTV 220
             G++T+ T+
Sbjct: 275 WWGTITLTTI 284


>gi|4885441 solute carrier family 17 (sodium phosphate), member 4
           [Homo sapiens]
          Length = 497

 Score = 28.9 bits (63), Expect = 8.7
 Identities = 62/316 (19%), Positives = 125/316 (39%), Gaps = 58/316 (18%)

Query: 77  WLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAII--GIIFIKEKWKPKDFLRRY 134
           +L LF+ L    GV         +L++ L  V  IA  ++  G   I  KW P   L R 
Sbjct: 150 FLTLFIPLAANAGV---------ALLIVLRIVQGIAQVMVLTGQYSIWVKWAPP--LERS 198

Query: 135 VLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYF- 193
            L+ +    +++G++++          +    +    + WP++ Y+   I   C  L+F 
Sbjct: 199 QLTTIAGSGSMLGSFIV----------LLAGGLLCQTIGWPYVFYIFGGIGCACCPLWFP 248

Query: 194 ----------YKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVL-SIQGNLQLDYPIF 242
                     +        +V  L          + ++A+   L L +I  +   +Y +F
Sbjct: 249 LIYDDPVNHPFISAGEKRYIVCSLAQQDCSPGWSLPIRAMIKSLPLWAILVSYFCEYWLF 308

Query: 243 YVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLH 302
           Y +   M  T  Y ++ L   + + DS +++++ +++     I  G +   DF+    + 
Sbjct: 309 YTI---MAYTPTYISSVLQ--ANLRDSGILSALPFVVGCICIILGGLL--ADFLLSRKI- 360

Query: 303 ICMFALGCLIAFLGVFLITRNRKKPIPFEPYISMDAMPGMQNMHDKGMTVQPELKASFSY 362
           + +  +  L   +GV              P + + ++P +++ H   MT      A  S+
Sbjct: 361 LRLITIRKLFTAIGVLF------------PSVILVSLPWVRSSHSMTMTFLVLSSAISSF 408

Query: 363 ---GALENNDNISEIY 375
              GAL N  +I+  Y
Sbjct: 409 CESGALVNFLDIAPRY 424


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,168,133
Number of Sequences: 37866
Number of extensions: 507595
Number of successful extensions: 1608
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1568
Number of HSP's gapped (non-prelim): 22
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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