Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 18105056

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18105056 vacuolar protein sorting 33A [Homo sapiens]
         (596 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18105056 vacuolar protein sorting 33A [Homo sapiens]              1185   0.0  
gi|119829191 vacuolar protein sorting 33B (yeast homolog)) [Homo...   290   2e-78
gi|18105063 vacuolar protein sorting 45A [Homo sapiens]                67   6e-11
gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens]         58   3e-08
gi|73760415 syntaxin binding protein 1 isoform b [Homo sapiens]        55   1e-07
gi|118600975 syntaxin binding protein 3 [Homo sapiens]                 52   2e-06
gi|188528901 syntaxin binding protein 2 isoform b [Homo sapiens]       50   6e-06
gi|188528689 syntaxin binding protein 2 isoform a [Homo sapiens]       50   6e-06
gi|33469966 vesicle transport-related protein isoform a [Homo sa...    44   6e-04
gi|33469978 vesicle transport-related protein isoform b [Homo sa...    43   0.001
gi|119226220 membrane-spanning 4-domains, subfamily A, member 14...    35   0.20 
gi|119226217 membrane-spanning 4-domains, subfamily A, member 14...    35   0.20 
gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I, ...    34   0.44 
gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I, ...    34   0.44 
gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, al...    34   0.44 
gi|20149560 syntaxin 4 [Homo sapiens]                                  33   0.74 
gi|4504705 inositol polyphosphate-4-phosphatase, type 1 isoform ...    32   1.7  
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    31   2.8  
gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens]                  30   6.3  
gi|31542785 sec1 family domain containing 2 [Homo sapiens]             30   6.3  
gi|94721261 2',3'-cyclic nucleotide 3' phosphodiesterase [Homo s...    30   8.2  
gi|4505343 nuclear cap binding protein subunit 1, 80kDa [Homo sa...    30   8.2  
gi|50345870 DENN/MADD domain containing 3 [Homo sapiens]               30   8.2  

>gi|18105056 vacuolar protein sorting 33A [Homo sapiens]
          Length = 596

 Score = 1185 bits (3066), Expect = 0.0
 Identities = 596/596 (100%), Positives = 596/596 (100%)

Query: 1   MAAHLSYGRVNLNVLREAVRRELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEV 60
           MAAHLSYGRVNLNVLREAVRRELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEV
Sbjct: 1   MAAHLSYGRVNLNVLREAVRRELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEV 60

Query: 61  EKMFTLKGNRLPAADVKNIIFFVRPRLELMDIIAENVLSEDRRGPTRDFHILFVPRRSLL 120
           EKMFTLKGNRLPAADVKNIIFFVRPRLELMDIIAENVLSEDRRGPTRDFHILFVPRRSLL
Sbjct: 61  EKMFTLKGNRLPAADVKNIIFFVRPRLELMDIIAENVLSEDRRGPTRDFHILFVPRRSLL 120

Query: 121 CEQRLKDLGVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLM 180
           CEQRLKDLGVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLM
Sbjct: 121 CEQRLKDLGVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLM 180

Query: 181 TLQALYGTIPQIFGKGECARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPL 240
           TLQALYGTIPQIFGKGECARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPL
Sbjct: 181 TLQALYGTIPQIFGKGECARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPL 240

Query: 241 ATQLTYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIR 300
           ATQLTYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIR
Sbjct: 241 ATQLTYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIR 300

Query: 301 DKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIAEL 360
           DKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIAEL
Sbjct: 301 DKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIAEL 360

Query: 361 IKDVTTSEDFFDKLTVEQEFMSGIDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGL 420
           IKDVTTSEDFFDKLTVEQEFMSGIDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGL
Sbjct: 361 IKDVTTSEDFFDKLTVEQEFMSGIDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGL 420

Query: 421 KQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKTLRLWMDDVNEQ 480
           KQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKTLRLWMDDVNEQ
Sbjct: 421 KQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKTLRLWMDDVNEQ 480

Query: 481 NPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGLQKKRQPG 540
           NPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGLQKKRQPG
Sbjct: 481 NPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGLQKKRQPG 540

Query: 541 ENRVTLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNGTSWIEALMEKPF 596
           ENRVTLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNGTSWIEALMEKPF
Sbjct: 541 ENRVTLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNGTSWIEALMEKPF 596


>gi|119829191 vacuolar protein sorting 33B (yeast homolog)) [Homo
           sapiens]
          Length = 617

 Score =  290 bits (743), Expect = 2e-78
 Identities = 196/620 (31%), Positives = 319/620 (51%), Gaps = 56/620 (9%)

Query: 11  NLNVLREAVRRELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKGNR 70
           + ++L+   R +L   L++  G K +  +  L  P   IA  S+LK+HEV+K++ ++ N+
Sbjct: 14  DFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVE-NK 72

Query: 71  LPAADVKNIIFFVRPRLELMDIIAENVLSEDRRGPTRDFHILFVPRRSLLCEQRLKDLGV 130
              +  + + F VRPR++ M  IA  V ++   G TR + ++F P++   CE  L++ G+
Sbjct: 73  PALSSNEQLCFLVRPRIKNMRYIASLVNADKLAGRTRKYKVIFSPQKFYACEMVLEEEGI 132

Query: 131 LGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLMTLQALYGTIP 190
            G  +  +E++  L+P D DLLSME    F++ +LEGDQ  +   A+ L  L  LYG  P
Sbjct: 133 YGD-VSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFP 191

Query: 191 QIFGKGECARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPLATQLTYEGLI 250
             +G G CA+    +   ++ E  G      P   ++ LLDR+VD +T L +Q+ YEGL+
Sbjct: 192 NCYGIGRCAKMAYELWRNLEEEEDGETKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLV 251

Query: 251 DEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNFNAVGSV 310
           D+ + I+   V   PE  +  K           + K+ LN+ ++++ EIR+++F+ V   
Sbjct: 252 DDTFRIKCGSVDFGPEVTSSDK-----------SLKVLLNAEDKVFNEIRNEHFSNVFGF 300

Query: 311 LSKKAKIISAAFEERHNAKTVGEIKQFVSQ-LPHMQAARGSLANHTSIAELIKDVTTSED 369
           LS+KA+ + A + +R     + ++K FVSQ L  ++     L+ H    E I    T +D
Sbjct: 301 LSQKARNLQAQY-DRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQD 359

Query: 370 FFDKLTVEQEFMSGIDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGLKQKVLDYYK 429
           F + +  E   + G +  +  +YIE+ I ++ S I+ LRL+CL S+  +GL  K     K
Sbjct: 360 FQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLK 419

Query: 430 REILQTYGYEHILTLHNLEKAGLLKPQTGG------------------------------ 459
            + LQ+YG EH+LT  NL +AGLL  Q  G                              
Sbjct: 420 TQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVESKVSKLVTDKAAGKITDAFSSLA 479

Query: 460 -RNNYPTIRKTLRLWMDDVNEQN---PTDISYVYSG-YAPLSVR-LAQLLSRPGWRSIEE 513
            R+N+  I K L L      E +   P D++YV+ G Y PLS R + Q+L R  W+ ++E
Sbjct: 480 KRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFGGAYVPLSCRIIEQVLERRSWQGLDE 539

Query: 514 VLRILPGPHFEERQPLPTGLQKKRQPGENRVTLIFFLGGVTFAEIAALRFLSQLEDGGTE 573
           V+R+L    F          + K      R+ L+ FLGG TF+EI+ALRFL +  + G  
Sbjct: 540 VVRLLNCSDFAFTDMTK---EDKASSESLRLILVVFLGGCTFSEISALRFLGR--EKGYR 594

Query: 574 YVIATTKLMNGTSWIEALME 593
           ++  TT + N    +EA+ E
Sbjct: 595 FIFLTTAVTNSARLMEAMSE 614


>gi|18105063 vacuolar protein sorting 45A [Homo sapiens]
          Length = 570

 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 82/375 (21%), Positives = 148/375 (39%), Gaps = 37/375 (9%)

Query: 18  AVRRELREFL-DKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKGNRLPAADV 76
           AV++ + + + D   G K ++ D+  TG   ++   S + + EV     +          
Sbjct: 6   AVKQYISKMIEDSGPGMKVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKH 65

Query: 77  KNIIFFVRPRLELMDIIAENVLSEDRRGPTRDFHILFVPRRSLLCEQRLKDLGVLGS--- 133
              I F+RP  E +D I + +     R P   + I F+   +++ +  +K L        
Sbjct: 66  LKAICFLRPTKENVDYIIQEL-----RRPK--YTIYFIYFSNVISKSDVKSLAEADEQEV 118

Query: 134 FIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLMTLQALYGTIPQIF 193
               +E+  D I  +  L S+   G  +      D   L    +GL  L       P I 
Sbjct: 119 VAEVQEFYGDYIAVNPHLFSLNILGCCQG--RNWDPAQLSRTTQGLTALLLSLKKCPMIR 176

Query: 194 GK---------GECARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPLATQL 244
            +          EC +QV      +   F   +  + P+   LL+LDR  D +TPL  Q 
Sbjct: 177 YQLSSEAAKRLAECVKQVITKEYEL---FEFRRTEVPPL---LLILDRCDDAITPLLNQW 230

Query: 245 TYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNF 304
           TY+ ++ E+ GI N+ + L       K   +    L  E  +   N+    +AEI     
Sbjct: 231 TYQAMVHELLGINNNRIDLSRVPGISKDLRE--VVLSAENDEFYANNMYLNFAEIGSNIK 288

Query: 305 NAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIAELIKDV 364
           N +     KK K       E+   +++ ++K FV   P  +   G+++ H ++   +  +
Sbjct: 289 NLMEDFQKKKPK-------EQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRL 341

Query: 365 TTSEDFFDKLTVEQE 379
            +  +  +   VEQE
Sbjct: 342 VSERNLLEVSEVEQE 356


>gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens]
          Length = 603

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 96/490 (19%), Positives = 192/490 (39%), Gaps = 66/490 (13%)

Query: 139 EYSLDLIPFDGDLLSMESEGAFKECY----LEGDQTSLYHAAKGLMTLQALYGTIPQIFG 194
           E ++  +P++  + S++S  +F+  Y     +     L   A+ + TL A     P +  
Sbjct: 132 EINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRY 191

Query: 195 KGE------CARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPLATQLTYEG 248
           +GE       A+ + + +   K +              LL+LDR  D  +P+  +LT++ 
Sbjct: 192 RGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQA 251

Query: 249 LIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNFNAVG 308
           +  ++  I+N   K        +  G G        K++ L+  ++L+  +R K+   V 
Sbjct: 252 MSYDLLPIENDVYKY-------ETSGIG----EARVKEVLLDEDDDLWIALRHKHIAEVS 300

Query: 309 SVLSKKAKIISAAFEERHNAK-TVGEIKQFVSQLPHMQAARGSLANHTSIAELIKDVTTS 367
             +++  K  S++       K T+ ++ Q + ++P  Q      + H  +AE    +   
Sbjct: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAE--DCMKHY 358

Query: 368 EDFFDKL-TVEQEFMSGIDT------DKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGL 420
           +   DKL  VEQ+   G D       D +   +   +    S    +R++ L     +G+
Sbjct: 359 QGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGI 418

Query: 421 KQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIR-KTLRLWMDDVNE 479
            ++ L+   +          I+T  N+   G+           P +   TLR       +
Sbjct: 419 TEENLNKLIQHAQIPPEDSEIIT--NMAHLGV-----------PIVTDSTLRRRSKPERK 465

Query: 480 QNPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGL------ 533
           +  ++ +Y  S + P+   + +        +IE+ L     P+   R             
Sbjct: 466 ERISEQTYQLSRWTPIIKDIME-------DTIEDKLDTKHYPYISTRSSASFSTTAVSAR 518

Query: 534 ----QKKRQPGENRV---TLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNGTS 586
                K + PGE R     +IF LGGV+  E+     ++Q  +G  E +I +T ++  T 
Sbjct: 519 YGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQ-ANGKWEVLIGSTHILTPTK 577

Query: 587 WIEALMEKPF 596
           ++  L    F
Sbjct: 578 FLMDLRHPDF 587


>gi|73760415 syntaxin binding protein 1 isoform b [Homo sapiens]
          Length = 594

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 94/485 (19%), Positives = 190/485 (39%), Gaps = 66/485 (13%)

Query: 139 EYSLDLIPFDGDLLSMESEGAFKECY----LEGDQTSLYHAAKGLMTLQALYGTIPQIFG 194
           E ++  +P++  + S++S  +F+  Y     +     L   A+ + TL A     P +  
Sbjct: 132 EINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRY 191

Query: 195 KGE------CARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPLATQLTYEG 248
           +GE       A+ + + +   K +              LL+LDR  D  +P+  +LT++ 
Sbjct: 192 RGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQA 251

Query: 249 LIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNFNAVG 308
           +  ++  I+N   K        +  G G        K++ L+  ++L+  +R K+   V 
Sbjct: 252 MSYDLLPIENDVYKY-------ETSGIG----EARVKEVLLDEDDDLWIALRHKHIAEVS 300

Query: 309 SVLSKKAKIISAAFEERHNAK-TVGEIKQFVSQLPHMQAARGSLANHTSIAELIKDVTTS 367
             +++  K  S++       K T+ ++ Q + ++P  Q      + H  +AE    +   
Sbjct: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAE--DCMKHY 358

Query: 368 EDFFDKL-TVEQEFMSGIDT------DKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGL 420
           +   DKL  VEQ+   G D       D +   +   +    S    +R++ L     +G+
Sbjct: 359 QGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGI 418

Query: 421 KQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIR-KTLRLWMDDVNE 479
            ++ L+   +          I+T  N+   G+           P +   TLR       +
Sbjct: 419 TEENLNKLIQHAQIPPEDSEIIT--NMAHLGV-----------PIVTDSTLRRRSKPERK 465

Query: 480 QNPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGL------ 533
           +  ++ +Y  S + P+   + +        +IE+ L     P+   R             
Sbjct: 466 ERISEQTYQLSRWTPIIKDIME-------DTIEDKLDTKHYPYISTRSSASFSTTAVSAR 518

Query: 534 ----QKKRQPGENRV---TLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNGTS 586
                K + PGE R     +IF LGGV+  E+     ++Q  +G  E +I +T ++    
Sbjct: 519 YGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQ-ANGKWEVLIGSTHILTPQK 577

Query: 587 WIEAL 591
            ++ L
Sbjct: 578 LLDTL 582


>gi|118600975 syntaxin binding protein 3 [Homo sapiens]
          Length = 592

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 104/598 (17%), Positives = 225/598 (37%), Gaps = 82/598 (13%)

Query: 34  KAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKGNRLPAADVKNIIFFVRPRLELMDII 93
           K ++ DE+ T       + + L E  +  +  +  NR P   +K  ++F+ P  + +D  
Sbjct: 33  KIMLLDEFTTKLLASCCKMTDLLEEGITVVENIYKNREPVRQMK-ALYFITPTSKSVDCF 91

Query: 94  AENVLSEDRRGPTRDFHILFVPRRSLLCEQRL--KDLGVLGSFIHR-EEYSLDLIPFDGD 150
             +  S+      +  +I F       C   L  K        I R +E ++  IP +  
Sbjct: 92  LHDFASKSEN-KYKAAYIYFTD----FCPDNLFNKIKASCSKSIRRCKEINISFIPHESQ 146

Query: 151 LLSMESEGAFKECY------LEGDQTSLYHAAKGLMTLQALYGTIPQIFGKGECARQVAN 204
           + +++   AF  CY       +G    +   A  ++T+ A     P +  K +     + 
Sbjct: 147 VYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVTVCATLDENPGVRYKSKPLDNASK 206

Query: 205 M--MIRMKRE--FTGSQNSIFP--VFDNLLLLDRNVDLLTPLATQLTYEGLIDEIYGIQN 258
           +  ++  K E  +   + S+        LL++DR  D ++ +  +LT++ +         
Sbjct: 207 LAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAM--------- 257

Query: 259 SYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNFNAVGSVLSKKAKII 318
           +Y  LP E    K + DG      + K+  L   ++L+  IR ++   V   + K  K I
Sbjct: 258 AYDLLPIENDTYKYKTDG------KEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEI 311

Query: 319 SAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIAELIKDVTTSEDFFDKL-TVE 377
           S+  +      ++  + Q + ++PH +        H ++AE    +   +   +KL   E
Sbjct: 312 SSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAE--DCMNKFKLNIEKLCKTE 369

Query: 378 QEFMSGIDT------DKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGLKQKVLDYY--- 428
           Q+   G D       D +   +   + + H     +R + L     +G  ++ LD     
Sbjct: 370 QDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQN 429

Query: 429 -----KREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKT--LRLWMDDVNEQN 481
                + ++++ + Y  +  +   ++   L+        +   R T  ++  M+D  +  
Sbjct: 430 VKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKDIMEDAIDNR 489

Query: 482 PTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGLQKKRQPGE 541
                + Y    P             W           G     ++P    L+ ++   +
Sbjct: 490 LDSKEWPYCSQCPAV-----------WNG--------SGAVSARQKPRANYLEDRKNGSK 530

Query: 542 NRVTLIFFLGGVTFAEIAALRFLSQLEDG-----GTEYVIATTKLMNGTSWIEALMEK 594
               ++F +GG+T++E+     +SQ         G+ +V+   KL++    +    +K
Sbjct: 531 ---LIVFVIGGITYSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDK 585


>gi|188528901 syntaxin binding protein 2 isoform b [Homo sapiens]
          Length = 590

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 93/487 (19%), Positives = 194/487 (39%), Gaps = 70/487 (14%)

Query: 138 EEYSLDLIPFDGDLLSMESEGAFKECYL----EGDQTSLYHAAKGLMTLQALYGTIPQI- 192
           +E  L  +P++  + S+++  +    Y     E     L   A+ + TL A     P I 
Sbjct: 128 KEIHLAFLPYEAQVFSLDAPHSTYNLYCPFRAEERTRQLEVLAQQIATLCATLQEYPAIR 187

Query: 193 FGKG-ECARQVANMMIRMKREFTGSQNSIFP----VFDNLLLLDRNVDLLTPLATQLTYE 247
           + KG E   Q+A+ ++     F     S+          LL++DR  D ++PL  +LT++
Sbjct: 188 YRKGPEDTAQLAHAVLAKLNAFKADTPSLGEGPEKTRSQLLIMDRAADPVSPLLHELTFQ 247

Query: 248 GLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNFNAV 307
            +  ++  I+    +      +  ++           K + L+  ++L+ E+R  +   V
Sbjct: 248 AMAYDLLDIEQDTYRYETTGLSEARE-----------KAVLLDEDDDLWVELRHMHIADV 296

Query: 308 GSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIA-ELIKDVTT 366
              +++  +    +     +   + ++ Q + ++P  Q      + H  +A + +K    
Sbjct: 297 SKKVTELLRTFCESKRLTTDKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKHFKG 356

Query: 367 SEDFFDKL-TVEQEFMSGIDT--DKVNNYIE-------DCIAQKHSLIKVLRLVCLQSVC 416
           S    +KL +VEQ+   G D   +K+ + ++       D     +  I+VL L  L    
Sbjct: 357 S---VEKLCSVEQDLAMGSDAEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYIL---- 409

Query: 417 NSGLKQKVLDYYKREILQTYGYE-HILTLHNLEKAGLLKPQTGGRNNYPTIRKTLRLWMD 475
              L+  V +    +++Q    + H   + NLE+ G      GG      +    R+   
Sbjct: 410 ---LRNGVSEENLAKLIQHANVQAHSSLIRNLEQLGGTVTNPGGSGTSSRLEPRERM--- 463

Query: 476 DVNEQNPTDISYVYSGYAP-----LSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLP 530
                 PT   Y  S + P     +   +   L R  W  + +     P P    +  + 
Sbjct: 464 -----EPT---YQLSRWTPVIKDVMEDAVEDRLDRNLWPFVSD-----PAPTASSQAAVS 510

Query: 531 T--GLQKKRQPG-ENRV---TLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNG 584
              G   K + G E R     +++ +GGV  +E+ A   +++  +G  E +I ++ ++  
Sbjct: 511 ARFGHWHKNKAGIEARAGPRLIVYVMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTP 570

Query: 585 TSWIEAL 591
           T +++ L
Sbjct: 571 TRFLDDL 577


>gi|188528689 syntaxin binding protein 2 isoform a [Homo sapiens]
          Length = 593

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 93/487 (19%), Positives = 194/487 (39%), Gaps = 70/487 (14%)

Query: 138 EEYSLDLIPFDGDLLSMESEGAFKECYL----EGDQTSLYHAAKGLMTLQALYGTIPQI- 192
           +E  L  +P++  + S+++  +    Y     E     L   A+ + TL A     P I 
Sbjct: 131 KEIHLAFLPYEAQVFSLDAPHSTYNLYCPFRAEERTRQLEVLAQQIATLCATLQEYPAIR 190

Query: 193 FGKG-ECARQVANMMIRMKREFTGSQNSIFP----VFDNLLLLDRNVDLLTPLATQLTYE 247
           + KG E   Q+A+ ++     F     S+          LL++DR  D ++PL  +LT++
Sbjct: 191 YRKGPEDTAQLAHAVLAKLNAFKADTPSLGEGPEKTRSQLLIMDRAADPVSPLLHELTFQ 250

Query: 248 GLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNFNAV 307
            +  ++  I+    +      +  ++           K + L+  ++L+ E+R  +   V
Sbjct: 251 AMAYDLLDIEQDTYRYETTGLSEARE-----------KAVLLDEDDDLWVELRHMHIADV 299

Query: 308 GSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIA-ELIKDVTT 366
              +++  +    +     +   + ++ Q + ++P  Q      + H  +A + +K    
Sbjct: 300 SKKVTELLRTFCESKRLTTDKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKHFKG 359

Query: 367 SEDFFDKL-TVEQEFMSGIDT--DKVNNYIE-------DCIAQKHSLIKVLRLVCLQSVC 416
           S    +KL +VEQ+   G D   +K+ + ++       D     +  I+VL L  L    
Sbjct: 360 S---VEKLCSVEQDLAMGSDAEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYIL---- 412

Query: 417 NSGLKQKVLDYYKREILQTYGYE-HILTLHNLEKAGLLKPQTGGRNNYPTIRKTLRLWMD 475
              L+  V +    +++Q    + H   + NLE+ G      GG      +    R+   
Sbjct: 413 ---LRNGVSEENLAKLIQHANVQAHSSLIRNLEQLGGTVTNPGGSGTSSRLEPRERM--- 466

Query: 476 DVNEQNPTDISYVYSGYAP-----LSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLP 530
                 PT   Y  S + P     +   +   L R  W  + +     P P    +  + 
Sbjct: 467 -----EPT---YQLSRWTPVIKDVMEDAVEDRLDRNLWPFVSD-----PAPTASSQAAVS 513

Query: 531 T--GLQKKRQPG-ENRV---TLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNG 584
              G   K + G E R     +++ +GGV  +E+ A   +++  +G  E +I ++ ++  
Sbjct: 514 ARFGHWHKNKAGIEARAGPRLIVYVMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTP 573

Query: 585 TSWIEAL 591
           T +++ L
Sbjct: 574 TRFLDDL 580


>gi|33469966 vesicle transport-related protein isoform a [Homo
           sapiens]
          Length = 642

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 75/403 (18%), Positives = 154/403 (38%), Gaps = 58/403 (14%)

Query: 34  KAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKGNRLPAADVKNIIFFVRPRLELMDII 93
           K +++D +       +     L++  +     L  +R P  DV   ++FV P  E +D +
Sbjct: 44  KVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVP-AVYFVMPTEENIDRM 102

Query: 94  AENVLSEDRRGPTRDFHILFVPRRSLLCEQRLKDLG---VLGSFIHR-----EEYSLDLI 145
            +++    R      +++ F+   S +   +L+D+    +  S + +     ++Y L+ I
Sbjct: 103 CQDL----RNQLYESYYLNFI---SAISRSKLEDIANAALAASAVTQVAKVFDQY-LNFI 154

Query: 146 PFDGDLLSMESEGAFKECYLEGD---------QTSLYHAAKGLMTLQALYGTIPQI-FGK 195
             + D+  + ++      Y   +         +T +      L       G +P I   +
Sbjct: 155 TLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSR 214

Query: 196 GECARQVANMMIRMKRE-FTGSQNSIFP---------VFDN--LLLLDRNVDLLTPLATQ 243
           G  A  VA  + +  RE    ++NS+F           F    L+L+DRN+DL TPL   
Sbjct: 215 GTAAEMVAVKLDKKLRENLRDARNSLFTGDTLGAGQFSFQRPLLVLVDRNIDLATPLHHT 274

Query: 244 LTYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKN 303
            TY+ L+ ++     + V L  E    +    G +      K   L   ++ + + +   
Sbjct: 275 WTYQALVHDVLDFHLNRVNL-EESSGVENSPAGARPKRKNKKSYDLTPVDKFWQKHKGSP 333

Query: 304 FNAVGSVLSKKAKIISAAFEERHNAKTV------------------GEIKQFVSQLPHMQ 345
           F  V   + ++ +   A  +E    K++                   ++   VS LP + 
Sbjct: 334 FPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELL 393

Query: 346 AARGSLANHTSIAELIKDVTTSEDFFDKLTVEQEFMSGIDTDK 388
             +  +  HT++A  + +   +         E++ MS    DK
Sbjct: 394 EKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTLDK 436


>gi|33469978 vesicle transport-related protein isoform b [Homo
           sapiens]
          Length = 575

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 49/233 (21%), Positives = 90/233 (38%), Gaps = 32/233 (13%)

Query: 187 GTIPQI-FGKGECARQVANMMIRMKRE-FTGSQNSIFP---------VFDN--LLLLDRN 233
           G +P I   +G  A  VA  + +  RE    ++NS+F           F    L+L+DRN
Sbjct: 138 GAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDTLGAGQFSFQRPLLVLVDRN 197

Query: 234 VDLLTPLATQLTYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAE 293
           +DL TPL    TY+ L+ ++     + V L  E    +    G +      K   L   +
Sbjct: 198 IDLATPLHHTWTYQALVHDVLDFHLNRVNL-EESSGVENSPAGARPKRKNKKSYDLTPVD 256

Query: 294 ELYAEIRDKNFNAVGSVLSKKAKIISAAFEERHNAKTV------------------GEIK 335
           + + + +   F  V   + ++ +   A  +E    K++                   ++ 
Sbjct: 257 KFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLT 316

Query: 336 QFVSQLPHMQAARGSLANHTSIAELIKDVTTSEDFFDKLTVEQEFMSGIDTDK 388
             VS LP +   +  +  HT++A  + +   +         E++ MS    DK
Sbjct: 317 SAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTLDK 369


>gi|119226220 membrane-spanning 4-domains, subfamily A, member 14
           isoform 2 [Homo sapiens]
          Length = 662

 Score = 35.0 bits (79), Expect = 0.20
 Identities = 27/66 (40%), Positives = 37/66 (56%), Gaps = 11/66 (16%)

Query: 486 SYVYSGYAPLSVRLAQ--LLSRPGWRSIEEV-----LRILPGPHF--EERQPLPTGLQKK 536
           S ++ GYA   + L++  L+S+PG +  E V       ILP P F  EE +PLP  L+KK
Sbjct: 182 SVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPSPKFSEEEIEPLPPTLEKK 241

Query: 537 RQPGEN 542
             P EN
Sbjct: 242 --PSEN 245


>gi|119226217 membrane-spanning 4-domains, subfamily A, member 14
           isoform 1 [Homo sapiens]
          Length = 679

 Score = 35.0 bits (79), Expect = 0.20
 Identities = 27/66 (40%), Positives = 37/66 (56%), Gaps = 11/66 (16%)

Query: 486 SYVYSGYAPLSVRLAQ--LLSRPGWRSIEEV-----LRILPGPHF--EERQPLPTGLQKK 536
           S ++ GYA   + L++  L+S+PG +  E V       ILP P F  EE +PLP  L+KK
Sbjct: 199 SVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPSPKFSEEEIEPLPPTLEKK 258

Query: 537 RQPGEN 542
             P EN
Sbjct: 259 --PSEN 262


>gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 1 [Homo sapiens]
          Length = 562

 Score = 33.9 bits (76), Expect = 0.44
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 85  PRLELMDIIAENVLSEDRRGPTR--DFHILFVPRRSLLCEQRLKDLGVLG-----SFIHR 137
           P+  L     E++  E RRG T   D H+  +P R+   E+ L  +G++       F+ +
Sbjct: 355 PQKALYSTAMESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKK 414

Query: 138 EEYSLDLIPFDGDLLSMESEGAFKE 162
            E+S   +  DGD +S+   G + E
Sbjct: 415 LEHSWKALVHDGDTVSVHRPGFYAE 439


>gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 4 [Homo sapiens]
          Length = 500

 Score = 33.9 bits (76), Expect = 0.44
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 85  PRLELMDIIAENVLSEDRRGPTR--DFHILFVPRRSLLCEQRLKDLGVLG-----SFIHR 137
           P+  L     E++  E RRG T   D H+  +P R+   E+ L  +G++       F+ +
Sbjct: 342 PQKALYSTAMESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKK 401

Query: 138 EEYSLDLIPFDGDLLSMESEGAFKE 162
            E+S   +  DGD +S+   G + E
Sbjct: 402 LEHSWKALVHDGDTVSVHRPGFYAE 426


>gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
           isoform 2 [Homo sapiens]
          Length = 549

 Score = 33.9 bits (76), Expect = 0.44
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 85  PRLELMDIIAENVLSEDRRGPTR--DFHILFVPRRSLLCEQRLKDLGVLG-----SFIHR 137
           P+  L     E++  E RRG T   D H+  +P R+   E+ L  +G++       F+ +
Sbjct: 342 PQKALYSTAMESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKK 401

Query: 138 EEYSLDLIPFDGDLLSMESEGAFKE 162
            E+S   +  DGD +S+   G + E
Sbjct: 402 LEHSWKALVHDGDTVSVHRPGFYAE 426


>gi|20149560 syntaxin 4 [Homo sapiens]
          Length = 297

 Score = 33.1 bits (74), Expect = 0.74
 Identities = 40/170 (23%), Positives = 69/170 (40%), Gaps = 31/170 (18%)

Query: 237 LTPLATQLTYEGLIDEIYGIQNSY------VKLPPEKFAPKKQ--GDGGKDLPTEAKKLQ 288
           +T LAT L  E +  E+  +++        ++L  +   P+K+   +    + T  +K Q
Sbjct: 67  VTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNTRMRKTQ 126

Query: 289 -----------LNSAEELYAEIRDKNFNAVGSVLSKKAKIISAAF---EERHNAKTVGEI 334
                      +N    + +E R+KN   +     ++ KI +A     EE       G+ 
Sbjct: 127 HGVLSQQFVELINKCNSMQSEYREKNVERI----RRQLKITNAGMVSDEELEQMLDSGQS 182

Query: 335 KQFVSQ-LPHMQAARGSL----ANHTSIAELIKDVTTSEDFFDKLTVEQE 379
           + FVS  L   Q  R +L    A H+ I +L + +    D F  L  E E
Sbjct: 183 EVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVE 232


>gi|4504705 inositol polyphosphate-4-phosphatase, type 1 isoform b
           [Homo sapiens]
          Length = 954

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 11/130 (8%)

Query: 114 VPR-RSLLCEQRLKDLGVLGSFIH-REEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTS 171
           +PR RS  C   L  L  LG  +H R+  ++D++    ++    +   F  C    D+T+
Sbjct: 807 LPRSRSQTCLPEL--LRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTA 864

Query: 172 LYHAAKGLMTLQALYGTIPQIFGKG-ECARQVANMMIRMKREFTGSQNSIFPVFDNLLLL 230
           +    +  + LQ  +G  PQ+F +  EC R +    +  ++  +G    + P+ D  L L
Sbjct: 865 MSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTREVVTQKNLSG----LVPIRD--LRL 918

Query: 231 DRNVDLLTPL 240
           D ++    PL
Sbjct: 919 DPSLLCSIPL 928


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 20/118 (16%)

Query: 240  LATQLTYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPT------EAKKLQLNSAE 293
            + TQL  E L DE+   +++ ++L     A K Q +  +DL T      E K+L +    
Sbjct: 1544 MRTQL--EELEDELQATEDAKLRLEVNMQAMKAQFE--RDLQTRDEQNEEKKRLLIKQVR 1599

Query: 294  ELYAEIRDKNFNAVGSVLSKK-----AKIISAAFEERHNAKTVGEIKQFVSQLPHMQA 346
            EL AE+ D+      +V SKK      K + A  E  + A+      + + QL  +QA
Sbjct: 1600 ELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKAR-----DEVIKQLRKLQA 1652


>gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens]
          Length = 1261

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 25/100 (25%), Positives = 48/100 (48%), Gaps = 4/100 (4%)

Query: 289 LNSAEELYAEIRDKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQLPHMQAAR 348
           L  +++L  ++   NFN++  ++    +++  A E + N+K +G I       P    A 
Sbjct: 800 LLKSKDLLRQLPASNFNSLHFLIVHLKRVVDHAEENKMNSKNLGVIFGPSLIRPRPTTAP 859

Query: 349 ---GSLANHTSIAELIKD-VTTSEDFFDKLTVEQEFMSGI 384
               SLA +++ A L++  +T S+  FD     Q+ M  I
Sbjct: 860 ITISSLAEYSNQARLVEFLITYSQKIFDGSLQPQDVMCSI 899


>gi|31542785 sec1 family domain containing 2 [Homo sapiens]
          Length = 684

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 12/44 (27%), Positives = 27/44 (61%)

Query: 539 PGENRVTLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLM 582
           P +  + ++F +GGVT +E+  ++ L      GT+ ++ +T+L+
Sbjct: 620 PSDYPLLILFVVGGVTVSEVKMVKDLVASLKPGTQVIVLSTRLL 663


>gi|94721261 2',3'-cyclic nucleotide 3' phosphodiesterase [Homo
           sapiens]
          Length = 421

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 6/77 (7%)

Query: 409 LVCLQSVCNSGLKQKVLDYYKREILQ-TYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIR 467
           L C    C+ G      +Y ++++L+ +Y     LT+  L     + P+T G        
Sbjct: 250 LHCTTKFCDYGKAPGAEEYAQQDVLKKSYSKAFTLTISAL----FVTPKTTGAR-VELSE 304

Query: 468 KTLRLWMDDVNEQNPTD 484
           + L+LW  DV++ +PTD
Sbjct: 305 QQLQLWPSDVDKLSPTD 321


>gi|4505343 nuclear cap binding protein subunit 1, 80kDa [Homo
           sapiens]
          Length = 790

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 2/75 (2%)

Query: 511 IEEVLRILPGPHFEERQPLPTGLQKKRQPGENRVTLIFFLGGVTFAEIAALRFLSQLEDG 570
           IEE L  +   H++ER+     L     PG+N++ L + +  V FAE+  L     ++  
Sbjct: 314 IEENLHCIIKSHWKERKTCAAQLVS--YPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVM 371

Query: 571 GTEYVIATTKLMNGT 585
            T  +I   KL  G+
Sbjct: 372 YTTLLIELCKLQPGS 386


>gi|50345870 DENN/MADD domain containing 3 [Homo sapiens]
          Length = 1198

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 18/150 (12%)

Query: 316 KIISAAFEERHNAKTVGE-IKQFVSQLPHMQAARGSLANHTSIAELIKDVTTSEDFFDKL 374
           ++IS   ++ H A  + + +K+F     HMQ   G        + ++KD +     F+ L
Sbjct: 619 RLISEILDKPHEASKLDDHVKKFKLPKKHMQL--GDFMKRVQESGIVKDASIIHRLFEAL 676

Query: 375 TVEQEFMSGIDT--DKVNNYIE-DCIAQKHSL--IKVLRLVCLQSVC--NSGLKQ----- 422
           TV QE     +T  D  N + E +  AQ+ SL  + +  L   + VC  +S +K      
Sbjct: 677 TVGQEKQIDPETFKDFYNCWKETEAEAQEVSLPWLVMEHLDKNECVCKLSSSVKTNLGVG 736

Query: 423 KVLDYYKREILQTY---GYEHILTLHNLEK 449
           K+    KR  L T    GY  I T  N+E+
Sbjct: 737 KIAMTQKRLFLLTEGRPGYLEISTFRNIEE 766


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,896,217
Number of Sequences: 37866
Number of extensions: 985597
Number of successful extensions: 1988
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1970
Number of HSP's gapped (non-prelim): 27
length of query: 596
length of database: 18,247,518
effective HSP length: 108
effective length of query: 488
effective length of database: 14,157,990
effective search space: 6909099120
effective search space used: 6909099120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press