Search of human proteins with 171906589

Search of human proteins with 171906589

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|171906589 branched chain ketoacid dehydrogenase kinase
isoform a [Homo sapiens]
         (412 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|171906589 branched chain ketoacid dehydrogenase kinase isofor...   830   0.0  
gi|171906593 branched chain ketoacid dehydrogenase kinase isofor...   738   0.0  
gi|19923736 pyruvate dehydrogenase kinase 2 [Homo sapiens]            162   4e-40
gi|4505689 pyruvate dehydrogenase kinase 1 [Homo sapiens]             159   3e-39
gi|4505693 pyruvate dehydrogenase kinase 4 [Homo sapiens]             154   2e-37
gi|215422338 pyruvate dehydrogenase kinase 3 isoform 1 [Homo sap...   150   2e-36
gi|4885545 pyruvate dehydrogenase kinase 3 isoform 2 [Homo sapiens]   150   2e-36
gi|169165066 PREDICTED: hypothetical protein [Homo sapiens]            33   0.62 
gi|169165483 PREDICTED: hypothetical protein [Homo sapiens]            32   0.80 
gi|169165882 PREDICTED: hypothetical protein [Homo sapiens]            32   0.80 
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    32   1.1  
gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo sa...    32   1.4  
gi|18921093 transient receptor potential cation channel, subfami...    31   2.3  
gi|148596957 myosin binding protein C, cardiac [Homo sapiens]          30   3.1  
gi|57863279 Meis1, myeloid ecotropic viral integration site 1 ho...    29   6.8  
gi|4505151 Meis homeobox 1 [Homo sapiens]                              29   8.9  
gi|66773086 SH3-binding kinase 1 [Homo sapiens]                        29   8.9  
gi|9506611 guanine nucleotide binding protein-like 3 (nucleolar)...    29   8.9  
gi|148922920 DENN/MADD domain containing 4B [Homo sapiens]             29   8.9  

>gi|171906589 branched chain ketoacid dehydrogenase kinase isoform a
           [Homo sapiens]
          Length = 412

 Score =  830 bits (2145), Expect = 0.0
 Identities = 412/412 (100%), Positives = 412/412 (100%)

Query: 1   MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID 60
           MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
Sbjct: 1   MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID 60

Query: 61  AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP 120
           AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
Sbjct: 61  AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP 120

Query: 121 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI 180
           TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
Sbjct: 121 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI 180

Query: 181 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR 240
           EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
Sbjct: 181 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR 240

Query: 241 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI 300
           LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI
Sbjct: 241 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI 300

Query: 301 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS 360
           TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
Sbjct: 301 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS 360

Query: 361 GPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI 412
           GPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI
Sbjct: 361 GPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI 412


>gi|171906593 branched chain ketoacid dehydrogenase kinase isoform b
           [Homo sapiens]
          Length = 365

 Score =  738 bits (1904), Expect = 0.0
 Identities = 365/365 (100%), Positives = 365/365 (100%)

Query: 1   MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID 60
           MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
Sbjct: 1   MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID 60

Query: 61  AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP 120
           AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
Sbjct: 61  AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP 120

Query: 121 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI 180
           TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
Sbjct: 121 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI 180

Query: 181 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR 240
           EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
Sbjct: 181 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR 240

Query: 241 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI 300
           LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI
Sbjct: 241 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI 300

Query: 301 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS 360
           TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
Sbjct: 301 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS 360

Query: 361 GPMHG 365
           GPMHG
Sbjct: 361 GPMHG 365


>gi|19923736 pyruvate dehydrogenase kinase 2 [Homo sapiens]
          Length = 407

 Score =  162 bits (411), Expect = 4e-40
 Identities = 108/338 (31%), Positives = 176/338 (52%), Gaps = 37/338 (10%)

Query: 90  SARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADE- 148
           S  +L+QELPVR+A+ +K    LP  +   P++  V   Y+++   + +F   KD  D  
Sbjct: 49  SFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLD-KDPEDHR 107

Query: 149 --AQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKL----VRYFLDKTLTSRLGIRM 202
             +Q+   +  + + H DVV  +A+G+ E +    D+ +    ++YFLD+   SR+ IRM
Sbjct: 108 TLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRM 167

Query: 203 LATHHLALHEDK-----PDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRI--- 254
           L   H  + +       P  +G I    +  ++++   D A+ LC+  Y  +P + I   
Sbjct: 168 LINQHTLIFDGSTNPAHPKHIGSIDPNCNVSEVVKDAYDMAKLLCDKYYMASPDLEIQEI 227

Query: 255 ---NGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLII 311
              N        ++P  L ++L EL KNAMRAT+ESH ++   +P + + +A  + DL I
Sbjct: 228 NAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVESH-ESSLILPPIKVMVALGEEDLSI 286

Query: 312 RISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQSGPMHGFGFGLP 371
           ++SDRGGG+  + ++R+  Y ++TA   T  P             G    P+ GFG+GLP
Sbjct: 287 KMSDRGGGVPLRKIERLFSYMYSTAP--TPQP-------------GTGGTPLAGFGYGLP 331

Query: 372 TSRAYAEYLGGSLQLQSLQGIGTD--VYLRLRHIDGRE 407
            SR YA+Y  G LQL S++G GTD  +YL+    D  E
Sbjct: 332 ISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVE 369


>gi|4505689 pyruvate dehydrogenase kinase 1 [Homo sapiens]
          Length = 436

 Score =  159 bits (403), Expect = 3e-39
 Identities = 113/341 (33%), Positives = 182/341 (53%), Gaps = 40/341 (11%)

Query: 90  SARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEA 149
           S  +L+QELPVR+A+ +K    LP  +   P++  V   YI++ Q+L DF     +  +A
Sbjct: 75  SFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKA 134

Query: 150 QY--CQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKL----VRYFLDKTLTSRLGIRML 203
            Y     V ++ + H DV+  +A+G+ E ++    + +    V+YFLD+   SR+ IRML
Sbjct: 135 IYDFTDTVIRIRNRHNDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRML 194

Query: 204 ATHHLALHEDKPD-------FVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRING 256
              H  L   K          +G I    +  ++I+   + ARRLC+  Y N+P + +  
Sbjct: 195 LNQHSLLFGGKGKGSPSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELE- 253

Query: 257 HVAARFP-------FIPMPLDYILPELLKNAMRATMESHLDTPYNVP-DVVITIANNDVD 308
            + A+ P       ++P  L +++ EL KNAMRATME H +     P  V +T+ N D  
Sbjct: 254 ELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNED-- 311

Query: 309 LIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQSGPMHGFGF 368
           L +++SDRGGG+  + +DR+ +Y ++TA      PR+            +++ P+ GFG+
Sbjct: 312 LTVKMSDRGGGVPLRKIDRLFNYMYSTAPR----PRVET----------SRAVPLAGFGY 357

Query: 369 GLPTSRAYAEYLGGSLQLQSLQGIGTD--VYLRLRHIDGRE 407
           GLP SR YA+Y  G L+L SL+G GTD  +Y++    D  E
Sbjct: 358 GLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIE 398


>gi|4505693 pyruvate dehydrogenase kinase 4 [Homo sapiens]
          Length = 411

 Score =  154 bits (388), Expect = 2e-37
 Identities = 101/329 (30%), Positives = 168/329 (51%), Gaps = 33/329 (10%)

Query: 90  SARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFPPIK--DQAD 147
           S  +L+QELPVR+A+ +K    LP  +    ++  V   YI++   L +F      DQ  
Sbjct: 53  SFAFLRQELPVRLANILKEIDILPTQLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKA 112

Query: 148 EAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKL----VRYFLDKTLTSRLGIRML 203
            + +   + ++ + H +VV  +A+G+ E +     + +    ++YFLD+   +R+  RML
Sbjct: 113 LSDFVDTLIKVRNRHHNVVPTMAQGIIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRML 172

Query: 204 ATHHLALHEDK----PDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVA 259
              H+ +  D     P  +G I        +++   + +R LC+  Y ++P +++   V 
Sbjct: 173 MNQHILIFSDSQTGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLT-QVN 231

Query: 260 ARFP-------FIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIR 312
            +FP       ++P  L ++L EL KNAMRAT+E   + P   P  VI +   + DL I+
Sbjct: 232 GKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKE-DLTIK 290

Query: 313 ISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQSGPMHGFGFGLPT 372
           ISDRGGG+  + +DR+  Y ++TA     D               +++ P+ GFG+GLP 
Sbjct: 291 ISDRGGGVPLRIIDRLFSYTYSTAPTPVMD--------------NSRNAPLAGFGYGLPI 336

Query: 373 SRAYAEYLGGSLQLQSLQGIGTDVYLRLR 401
           SR YA+Y  G L L SL G GTD  + L+
Sbjct: 337 SRLYAKYFQGDLNLYSLSGYGTDAIIYLK 365


>gi|215422338 pyruvate dehydrogenase kinase 3 isoform 1 [Homo
           sapiens]
          Length = 415

 Score =  150 bits (380), Expect = 2e-36
 Identities = 99/338 (29%), Positives = 174/338 (51%), Gaps = 33/338 (9%)

Query: 90  SARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEA 149
           S  +L++ELPVR+A+ ++    LP  +   P++  V   Y+++F +L ++     +  + 
Sbjct: 45  SYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDPQV 104

Query: 150 --QYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKLV----RYFLDKTLTSRLGIRML 203
              + Q++ ++ + H DVV  +A+G+ E ++    +  +    +YFLD+  T+R+  RML
Sbjct: 105 LDNFLQVLIKVRNRHNDVVPTMAQGVIEYKEKFGFDPFISTNIQYFLDRFYTNRISFRML 164

Query: 204 ATHHLAL-----HEDKPDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHV 258
              H  L     +   P  +G I    +   +++   + A+ LCE  Y  AP + +    
Sbjct: 165 INQHTLLFGGDTNPVHPKHIGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFN 224

Query: 259 AA------RFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIR 312
           A       +  ++P  L ++L EL KN+MRAT+E + D     P V   +     DL I+
Sbjct: 225 AKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVELYEDRKEGYPAVKTLVTLGKEDLSIK 284

Query: 313 ISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQSGPMHGFGFGLPT 372
           ISD GGG+  + +DR+ +Y ++TA   + +P               ++ P+ GFG+GLP 
Sbjct: 285 ISDLGGGVPLRKIDRLFNYMYSTAPRPSLEP--------------TRAAPLAGFGYGLPI 330

Query: 373 SRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESF 410
           SR YA Y  G L+L S++G+GTD  + L+ +    ESF
Sbjct: 331 SRLYARYFQGDLKLYSMEGVGTDAVIYLKALS--SESF 366


>gi|4885545 pyruvate dehydrogenase kinase 3 isoform 2 [Homo sapiens]
          Length = 406

 Score =  150 bits (380), Expect = 2e-36
 Identities = 99/338 (29%), Positives = 174/338 (51%), Gaps = 33/338 (9%)

Query: 90  SARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEA 149
           S  +L++ELPVR+A+ ++    LP  +   P++  V   Y+++F +L ++     +  + 
Sbjct: 45  SYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDPQV 104

Query: 150 --QYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKLV----RYFLDKTLTSRLGIRML 203
              + Q++ ++ + H DVV  +A+G+ E ++    +  +    +YFLD+  T+R+  RML
Sbjct: 105 LDNFLQVLIKVRNRHNDVVPTMAQGVIEYKEKFGFDPFISTNIQYFLDRFYTNRISFRML 164

Query: 204 ATHHLAL-----HEDKPDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHV 258
              H  L     +   P  +G I    +   +++   + A+ LCE  Y  AP + +    
Sbjct: 165 INQHTLLFGGDTNPVHPKHIGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFN 224

Query: 259 AA------RFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIR 312
           A       +  ++P  L ++L EL KN+MRAT+E + D     P V   +     DL I+
Sbjct: 225 AKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVELYEDRKEGYPAVKTLVTLGKEDLSIK 284

Query: 313 ISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQSGPMHGFGFGLPT 372
           ISD GGG+  + +DR+ +Y ++TA   + +P               ++ P+ GFG+GLP 
Sbjct: 285 ISDLGGGVPLRKIDRLFNYMYSTAPRPSLEP--------------TRAAPLAGFGYGLPI 330

Query: 373 SRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESF 410
           SR YA Y  G L+L S++G+GTD  + L+ +    ESF
Sbjct: 331 SRLYARYFQGDLKLYSMEGVGTDAVIYLKALS--SESF 366


>gi|169165066 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 32.7 bits (73), Expect = 0.62
 Identities = 24/69 (34%), Positives = 30/69 (43%), Gaps = 6/69 (8%)

Query: 19  PLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAIDAAAEKPSVRLTPTMMLYA 78
           P  G   A R R        HV    E    VTS + QSA       PS R+ P + L+A
Sbjct: 41  PTAGATSAARCRPR-----RHVAARSELRHFVTSHHRQSACSFRFLAPS-RIPPRLGLFA 94

Query: 79  GRSQDGSHL 87
           GR + G H+
Sbjct: 95  GRGEAGCHV 103


>gi|169165483 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 32.3 bits (72), Expect = 0.80
 Identities = 24/69 (34%), Positives = 30/69 (43%), Gaps = 6/69 (8%)

Query: 19  PLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAIDAAAEKPSVRLTPTMMLYA 78
           P  G   A R R        HV    E    VTS + QSA       PS R+ P + L+A
Sbjct: 41  PTAGATSAARCRPR-----RHVAARSELRHFVTSHHRQSACSFRFLAPS-RIPPRLGLFA 94

Query: 79  GRSQDGSHL 87
           GR + G H+
Sbjct: 95  GRGEAGYHV 103


>gi|169165882 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 32.3 bits (72), Expect = 0.80
 Identities = 24/69 (34%), Positives = 30/69 (43%), Gaps = 6/69 (8%)

Query: 19  PLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAIDAAAEKPSVRLTPTMMLYA 78
           P  G   A R R        HV    E    VTS + QSA       PS R+ P + L+A
Sbjct: 41  PTAGATSAARCRPR-----RHVAARSELRHFVTSHHRQSACSFRFLAPS-RIPPRLGLFA 94

Query: 79  GRSQDGSHL 87
           GR + G H+
Sbjct: 95  GRGEAGYHV 103


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 9/67 (13%)

Query: 8   RSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAIDAAAEKPS 67
           R+ P GGLP  PL GPAL  R  S +         +R  S +  S  + +   AA+ +P+
Sbjct: 791 RTSPYGGLPAAPLAGPALPARRLSRA---------SRPLSASQPSLPHGAPGPAASTRPA 841

Query: 68  VRLTPTM 74
              TP +
Sbjct: 842 SSSTPRL 848


>gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo
           sapiens]
          Length = 1174

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 45/197 (22%), Positives = 84/197 (42%), Gaps = 31/197 (15%)

Query: 11  PGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAIDAAAEKPSVRL 70
           PGG   +    G    L A+   AT+T +V  A++ SK   +   +S ++ ++ +P+  +
Sbjct: 181 PGGYFIIN---GSEKVLIAQEKMATNTVYV-FAKKDSKYAYTGECRSCLENSS-RPTSTI 235

Query: 71  TPTMMLYAG----RSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVH 126
             +M+   G    +S  G  ++ +  Y++QE+P+ I  R  GF      +     + H+ 
Sbjct: 236 WVSMLARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGF------VSDRDILEHI- 288

Query: 127 ELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKLV 186
              I  F+       +K   DEA   Q         +  V L   G R ++  +  EK +
Sbjct: 289 ---IYDFEDPEMMEMVKPSLDEAFVIQ---------EQNVALNFIGSRGAKPGVTKEKRI 336

Query: 187 RY---FLDKTLTSRLGI 200
           +Y    L K +   +G+
Sbjct: 337 KYAKEVLQKEMLPHVGV 353


>gi|18921093 transient receptor potential cation channel, subfamily
           M, member 6 [Homo sapiens]
          Length = 2022

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 28  RARSTSATDTHHVEMARERSKTVTSFYNQSAID--AAAEKPSVRLTPTMMLYAGRSQDGS 85
           RA +  A ++H V+ A E  K  +  + Q A+D    A K + R+  T++ Y  R+   S
Sbjct: 646 RAMAHEAKESHMVDDASEELKNYSKQFGQLALDLLEKAFKQNERMAMTLLTYELRNWSNS 705

Query: 86  HLLKSA 91
             LK A
Sbjct: 706 TCLKLA 711


>gi|148596957 myosin binding protein C, cardiac [Homo sapiens]
          Length = 1274

 Score = 30.4 bits (67), Expect = 3.1
 Identities = 14/58 (24%), Positives = 31/58 (53%), Gaps = 7/58 (12%)

Query: 257 HVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIRIS 314
           +++A+  F+ + +D++         +   + HLD P  +PD ++ +A N + L + IS
Sbjct: 624 NLSAKLHFMEVKIDFV-------PRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPIS 674


>gi|57863279 Meis1, myeloid ecotropic viral integration site 1
           homolog 3 isoform 2 [Homo sapiens]
          Length = 358

 Score = 29.3 bits (64), Expect = 6.8
 Identities = 20/99 (20%), Positives = 40/99 (40%)

Query: 272 ILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDY 331
           I P++  N MRA +  HL  PY   +    +A +    I+++++       + +  ++D 
Sbjct: 251 IFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQ 310

Query: 332 HFTTAEASTQDPRISPLFGHLDMHSGAQSGPMHGFGFGL 370
              T + +   P   P+ G+ +        P    G  L
Sbjct: 311 SNRTGQGAAFSPEGQPIGGYTETQPHVAVRPPGSVGMSL 349


>gi|4505151 Meis homeobox 1 [Homo sapiens]
          Length = 390

 Score = 28.9 bits (63), Expect = 8.9
 Identities = 23/104 (22%), Positives = 48/104 (46%), Gaps = 5/104 (4%)

Query: 272 ILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDY 331
           I P++  N MRA +  HL  PY   +    +A +    I+++++       + +  ++D 
Sbjct: 278 IFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQ 337

Query: 332 -HFTTAEASTQDPRISPLFGHL---DMHSGAQS-GPMHGFGFGL 370
            +   ++ +  +P   P+ G +     H G ++ GPM G G  +
Sbjct: 338 SNRAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNM 381


>gi|66773086 SH3-binding kinase 1 [Homo sapiens]
          Length = 424

 Score = 28.9 bits (63), Expect = 8.9
 Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 3/40 (7%)

Query: 10 GPGGGLPLRPLLGPALALRARSTSATD-THHVEMARERSK 48
          GPG G+PL  L     AL  R+ +A+D T H E+ RE  K
Sbjct: 24 GPGAGVPL--LTEDMQALTLRTLAASDVTKHYELVRELGK 61


>gi|9506611 guanine nucleotide binding protein-like 3
           (nucleolar)-like [Homo sapiens]
          Length = 582

 Score = 28.9 bits (63), Expect = 8.9
 Identities = 24/108 (22%), Positives = 41/108 (37%), Gaps = 25/108 (23%)

Query: 134 QKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKLVRYFLDKT 193
           Q+L  FP + D+A    Y                      +E RK +E   ++   LD  
Sbjct: 107 QELNMFPQLDDEATRKAY---------------------YKEFRKVVEYSDVILEVLDAR 145

Query: 194 LTSRLGIRMLATHHLALHEDKPDFVGIICTRLS--PKKIIEKWVDFAR 239
               LG R        L       + ++  ++   PK+++EKW+D+ R
Sbjct: 146 --DPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLR 191


>gi|148922920 DENN/MADD domain containing 4B [Homo sapiens]
          Length = 1496

 Score = 28.9 bits (63), Expect = 8.9
 Identities = 29/110 (26%), Positives = 42/110 (38%), Gaps = 3/110 (2%)

Query: 190 LDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARRLCEHKYG-- 247
           L   L   L + +L  H L +H  +PD +  +C  L        W      LC       
Sbjct: 405 LGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADV 464

Query: 248 -NAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVP 296
            +AP   I G  ++ F     P D I  +L  N +  T E  L +P  +P
Sbjct: 465 LSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQTEEKKLLSPRTLP 514


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,652,086
Number of Sequences: 37866
Number of extensions: 684288
Number of successful extensions: 1630
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1591
Number of HSP's gapped (non-prelim): 22
length of query: 412
length of database: 18,247,518
effective HSP length: 105
effective length of query: 307
effective length of database: 14,271,588
effective search space: 4381377516
effective search space used: 4381377516
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.