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Search of human proteins with 171460916
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]
(710 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|171460916 dynamin 1-like isoform 2 [Homo sapiens] 1388 0.0
gi|171460914 dynamin 1-like isoform 1 [Homo sapiens] 1374 0.0
gi|171460918 dynamin 1-like isoform 3 [Homo sapiens] 1359 0.0
gi|56549117 dynamin 1 isoform 2 [Homo sapiens] 459 e-129
gi|59853099 dynamin 1 isoform 1 [Homo sapiens] 459 e-129
gi|56549125 dynamin 2 isoform 4 [Homo sapiens] 452 e-127
gi|56549123 dynamin 2 isoform 2 [Homo sapiens] 451 e-126
gi|56549119 dynamin 2 isoform 3 [Homo sapiens] 450 e-126
gi|56549121 dynamin 2 isoform 1 [Homo sapiens] 448 e-126
gi|42544243 dynamin 3 isoform a [Homo sapiens] 437 e-122
gi|209915561 dynamin 3 isoform b [Homo sapiens] 437 e-122
gi|11342664 myxovirus resistance protein 2 [Homo sapiens] 196 8e-50
gi|222136619 myxovirus resistance protein 1 [Homo sapiens] 195 1e-49
gi|222136617 myxovirus resistance protein 1 [Homo sapiens] 195 1e-49
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens] 104 2e-22
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens] 104 2e-22
gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens] 104 2e-22
gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens] 104 2e-22
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens] 104 2e-22
gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens] 104 2e-22
gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens] 104 2e-22
gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens] 104 2e-22
gi|239756350 PREDICTED: UPF0621 protein C-like [Homo sapiens] 49 2e-05
gi|239750876 PREDICTED: UPF0621 protein C-like [Homo sapiens] 49 2e-05
gi|169208224 PREDICTED: UPF0621 protein C-like [Homo sapiens] 49 2e-05
gi|27262622 neuron navigator 1 [Homo sapiens] 34 0.54
gi|148746220 spermatogenesis associated, serine-rich 2 [Homo sap... 33 1.2
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (... 32 1.6
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (... 32 1.6
gi|73623033 serine (or cysteine) proteinase inhibitor, clade B (... 32 1.6
>gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]
Length = 710
Score = 1388 bits (3593), Expect = 0.0
Identities = 710/710 (100%), Positives = 710/710 (100%)
Query: 1 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 60
MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR
Sbjct: 1 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 60
Query: 61 RPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISG 120
RPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISG
Sbjct: 61 RPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISG 120
Query: 121 NNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSI 180
NNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSI
Sbjct: 121 NNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSI 180
Query: 181 ILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLG 240
ILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLG
Sbjct: 181 ILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLG 240
Query: 241 IIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDC 300
IIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDC
Sbjct: 241 IIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDC 300
Query: 301 LPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSEL 360
LPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSEL
Sbjct: 301 LPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSEL 360
Query: 361 CGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQ 420
CGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQ
Sbjct: 361 CGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQ 420
Query: 421 IKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTN 480
IKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTN
Sbjct: 421 IKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTN 480
Query: 481 EMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKLIQDSRRE 540
EMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKLIQDSRRE
Sbjct: 481 EMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKLIQDSRRE 540
Query: 541 TKNVASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLL 600
TKNVASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLL
Sbjct: 541 TKNVASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLL 600
Query: 601 DVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSEL 660
DVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSEL
Sbjct: 601 DVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSEL 660
Query: 661 VGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW 710
VGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW
Sbjct: 661 VGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW 710
>gi|171460914 dynamin 1-like isoform 1 [Homo sapiens]
Length = 736
Score = 1374 bits (3556), Expect = 0.0
Identities = 710/736 (96%), Positives = 710/736 (96%), Gaps = 26/736 (3%)
Query: 1 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 60
MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR
Sbjct: 1 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 60
Query: 61 RPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISG 120
RPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISG
Sbjct: 61 RPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISG 120
Query: 121 NNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSI 180
NNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSI
Sbjct: 121 NNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSI 180
Query: 181 ILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLG 240
ILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLG
Sbjct: 181 ILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLG 240
Query: 241 IIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDC 300
IIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDC
Sbjct: 241 IIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDC 300
Query: 301 LPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSEL 360
LPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSEL
Sbjct: 301 LPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSEL 360
Query: 361 CGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQ 420
CGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQ
Sbjct: 361 CGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQ 420
Query: 421 IKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTN 480
IKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTN
Sbjct: 421 IKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTN 480
Query: 481 EMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRD--------- 531
EMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRD
Sbjct: 481 EMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKSSKVPSAL 540
Query: 532 -----------------KLIQDSRRETKNVASGGGGVGDGVQEPTTGNWRGMLKTSKAEE 574
KLIQDSRRETKNVASGGGGVGDGVQEPTTGNWRGMLKTSKAEE
Sbjct: 541 APASQEPSPAASAEADGKLIQDSRRETKNVASGGGGVGDGVQEPTTGNWRGMLKTSKAEE 600
Query: 575 LLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRK 634
LLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRK
Sbjct: 601 LLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRK 660
Query: 635 NIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKAL 694
NIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKAL
Sbjct: 661 NIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKAL 720
Query: 695 QGASQIIAEIRETHLW 710
QGASQIIAEIRETHLW
Sbjct: 721 QGASQIIAEIRETHLW 736
>gi|171460918 dynamin 1-like isoform 3 [Homo sapiens]
Length = 699
Score = 1359 bits (3517), Expect = 0.0
Identities = 699/710 (98%), Positives = 699/710 (98%), Gaps = 11/710 (1%)
Query: 1 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 60
MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR
Sbjct: 1 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR 60
Query: 61 RPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISG 120
RPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISG
Sbjct: 61 RPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISG 120
Query: 121 NNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSI 180
NNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSI
Sbjct: 121 NNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSI 180
Query: 181 ILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLG 240
ILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLG
Sbjct: 181 ILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLG 240
Query: 241 IIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDC 300
IIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDC
Sbjct: 241 IIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDC 300
Query: 301 LPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSEL 360
LPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSEL
Sbjct: 301 LPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSEL 360
Query: 361 CGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQ 420
CGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQ
Sbjct: 361 CGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQ 420
Query: 421 IKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTN 480
IKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTN
Sbjct: 421 IKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTN 480
Query: 481 EMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKLIQDSRRE 540
EMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDK
Sbjct: 481 EMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDK-------- 532
Query: 541 TKNVASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLL 600
VASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLL
Sbjct: 533 ---VASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLL 589
Query: 601 DVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSEL 660
DVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSEL
Sbjct: 590 DVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSEL 649
Query: 661 VGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW 710
VGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW
Sbjct: 650 VGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW 699
>gi|56549117 dynamin 1 isoform 2 [Homo sapiens]
Length = 851
Score = 459 bits (1182), Expect = e-129
Identities = 251/541 (46%), Positives = 362/541 (66%), Gaps = 34/541 (6%)
Query: 1 MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
ME LIP++N+LQD F+ +G + + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 6 MEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
Query: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
RRPL+LQLV+ + E + +FLH K K +TDF+E+R EIE ET+R++
Sbjct: 66 RRPLVLQLVNATTE----------------YAEFLHCKGKKFTDFEEVRLEIEAETDRVT 109
Query: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
G NKG+SP PI+L+++SP+V+NLTLVDLPGMTKVPVGDQP DIE QIR+++++F++ N
Sbjct: 110 GTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENC 169
Query: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
+ILAV+ AN+D+A S+ALK+++EVDP G+RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 170 LILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
Query: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
G IGVVNRSQ DI+ KK +T ++ E F Y LA+R GT YL + LN+ L +HI
Sbjct: 230 GYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHI 289
Query: 298 RDCLPELKTRINVLAAQYQSLLNSYGEPVDD----KSATLLQLITKFATEYCNTIEGTAK 353
RD LP L+ ++ + + Y D K+ LLQ++ +FA ++ IEG+
Sbjct: 290 RDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGD 349
Query: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
I+T EL GGARI IFHE F L ++ +I AI+N G R LF P+++F
Sbjct: 350 QIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAF 409
Query: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
E +VK+Q+K++ EP L+CV++V E+ ++ C T++L ++P+L + + +VT +R
Sbjct: 410 ETIVKKQVKKIREPCLKCVDMVISELISTVRQC----TKKLQQYPRLREEMERIVTTHIR 465
Query: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKL 533
+R T E V L+ IELAY+NT H DF G N +QR N++ ++ S ++D++
Sbjct: 466 EREGRTKEQVMLLIDIELAYMNTNHEDF---IGFAN---AQQRSNQMNKKKTSG-NQDEI 518
Query: 534 I 534
+
Sbjct: 519 L 519
Score = 73.6 bits (179), Expect = 6e-13
Identities = 37/93 (39%), Positives = 54/93 (58%)
Query: 615 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674
+R E I L+ SY IV K ++D +PK +MH ++N+ K+ + SEL+ LY + L+
Sbjct: 656 ERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLM 715
Query: 675 TESEDMAQRRKEAADMLKALQGASQIIAEIRET 707
ES + AQRR E M AL+ A II +I T
Sbjct: 716 EESAEQAQRRDEMLRMYHALKEALSIIGDINTT 748
>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
Length = 864
Score = 459 bits (1182), Expect = e-129
Identities = 251/541 (46%), Positives = 362/541 (66%), Gaps = 34/541 (6%)
Query: 1 MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
ME LIP++N+LQD F+ +G + + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 6 MEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
Query: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
RRPL+LQLV+ + E + +FLH K K +TDF+E+R EIE ET+R++
Sbjct: 66 RRPLVLQLVNATTE----------------YAEFLHCKGKKFTDFEEVRLEIEAETDRVT 109
Query: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
G NKG+SP PI+L+++SP+V+NLTLVDLPGMTKVPVGDQP DIE QIR+++++F++ N
Sbjct: 110 GTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENC 169
Query: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
+ILAV+ AN+D+A S+ALK+++EVDP G+RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 170 LILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
Query: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
G IGVVNRSQ DI+ KK +T ++ E F Y LA+R GT YL + LN+ L +HI
Sbjct: 230 GYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHI 289
Query: 298 RDCLPELKTRINVLAAQYQSLLNSYGEPVDD----KSATLLQLITKFATEYCNTIEGTAK 353
RD LP L+ ++ + + Y D K+ LLQ++ +FA ++ IEG+
Sbjct: 290 RDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGD 349
Query: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
I+T EL GGARI IFHE F L ++ +I AI+N G R LF P+++F
Sbjct: 350 QIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAF 409
Query: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
E +VK+Q+K++ EP L+CV++V E+ ++ C T++L ++P+L + + +VT +R
Sbjct: 410 ETIVKKQVKKIREPCLKCVDMVISELISTVRQC----TKKLQQYPRLREEMERIVTTHIR 465
Query: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKL 533
+R T E V L+ IELAY+NT H DF G N +QR N++ ++ S ++D++
Sbjct: 466 EREGRTKEQVMLLIDIELAYMNTNHEDF---IGFAN---AQQRSNQMNKKKTSG-NQDEI 518
Query: 534 I 534
+
Sbjct: 519 L 519
Score = 73.6 bits (179), Expect = 6e-13
Identities = 37/93 (39%), Positives = 54/93 (58%)
Query: 615 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674
+R E I L+ SY IV K ++D +PK +MH ++N+ K+ + SEL+ LY + L+
Sbjct: 656 ERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLM 715
Query: 675 TESEDMAQRRKEAADMLKALQGASQIIAEIRET 707
ES + AQRR E M AL+ A II +I T
Sbjct: 716 EESAEQAQRRDEMLRMYHALKEALSIIGDINTT 748
>gi|56549125 dynamin 2 isoform 4 [Homo sapiens]
Length = 866
Score = 452 bits (1164), Expect = e-127
Identities = 251/537 (46%), Positives = 353/537 (65%), Gaps = 31/537 (5%)
Query: 1 MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
ME LIP++NKLQD F+++G + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 6 MEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
Query: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
RRPLILQL+ E +FLH K+K +TDFDE+RQEIE ET+R++
Sbjct: 66 RRPLILQLIFSKTEH----------------AEFLHCKSKKFTDFDEVRQEIEAETDRVT 109
Query: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
G NKG+SP PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QI+++IL+FIS +S
Sbjct: 110 GTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESS 169
Query: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
+ILAVT AN D+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 170 LILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
Query: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
G IGVVNRSQ DI KK + ++ E F Y +A+R GT +L +TLN+ L +HI
Sbjct: 230 GYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHI 289
Query: 298 RDCLPELKTRIN----VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAK 353
R+ LP L++++ L + + N + K+ LLQ++ +F ++ IEG+
Sbjct: 290 RESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGD 349
Query: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
++T EL GGARI IFHE F L ++ +I AI+N G R LF P+++F
Sbjct: 350 QVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAF 409
Query: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
E +VK+QI +L+EPSL+CV+LV E+ +I+ C+ ++L +P+L + +VT +R
Sbjct: 410 EAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCA----EKLSSYPRLREETERIVTTYIR 465
Query: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSR 530
+R T + + L+ IE +YINT H DF G N + N+ R +P+ V R
Sbjct: 466 EREGRTKDQILLLIDIEQSYINTNHEDF---IGFANAQQRSTQLNK-KRAIPNQVIR 518
Score = 72.0 bits (175), Expect = 2e-12
Identities = 36/90 (40%), Positives = 53/90 (58%)
Query: 615 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674
+R E I L+ SY I+ K+I+D +PK +MH ++N+ K + EL+ LY S+ L+
Sbjct: 646 ERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLM 705
Query: 675 TESEDMAQRRKEAADMLKALQGASQIIAEI 704
ES D AQRR + M AL+ A II +I
Sbjct: 706 EESADQAQRRDDMLRMYHALKEALNIIGDI 735
>gi|56549123 dynamin 2 isoform 2 [Homo sapiens]
Length = 870
Score = 451 bits (1160), Expect = e-126
Identities = 244/508 (48%), Positives = 342/508 (67%), Gaps = 27/508 (5%)
Query: 1 MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
ME LIP++NKLQD F+++G + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 6 MEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
Query: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
RRPLILQL+ E +FLH K+K +TDFDE+RQEIE ET+R++
Sbjct: 66 RRPLILQLIFSKTEH----------------AEFLHCKSKKFTDFDEVRQEIEAETDRVT 109
Query: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
G NKG+SP PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QI+++IL+FIS +S
Sbjct: 110 GTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESS 169
Query: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
+ILAVT AN D+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 170 LILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
Query: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
G IGVVNRSQ DI KK + ++ E F Y +A+R GT +L +TLN+ L +HI
Sbjct: 230 GYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHI 289
Query: 298 RDCLPELKTRIN----VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAK 353
R+ LP L++++ L + + N + K+ LLQ++ +F ++ IEG+
Sbjct: 290 RESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGD 349
Query: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
++T EL GGARI IFHE F L ++ +I AI+N G R LF P+++F
Sbjct: 350 QVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAF 409
Query: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
E +VK+QI +L+EPSL+CV+LV E+ +I+ C+ ++L +P+L + +VT +R
Sbjct: 410 EAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCA----EKLSSYPRLREETERIVTTYIR 465
Query: 474 KRLPVTNEMVHNLVAIELAYINTKHPDF 501
+R T + + L+ IE +YINT H DF
Sbjct: 466 EREGRTKDQILLLIDIEQSYINTNHEDF 493
Score = 72.0 bits (175), Expect = 2e-12
Identities = 36/90 (40%), Positives = 53/90 (58%)
Query: 615 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674
+R E I L+ SY I+ K+I+D +PK +MH ++N+ K + EL+ LY S+ L+
Sbjct: 650 ERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLM 709
Query: 675 TESEDMAQRRKEAADMLKALQGASQIIAEI 704
ES D AQRR + M AL+ A II +I
Sbjct: 710 EESADQAQRRDDMLRMYHALKEALNIIGDI 739
>gi|56549119 dynamin 2 isoform 3 [Homo sapiens]
Length = 866
Score = 450 bits (1157), Expect = e-126
Identities = 249/537 (46%), Positives = 351/537 (65%), Gaps = 31/537 (5%)
Query: 1 MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
ME LIP++NKLQD F+++G + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 6 MEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
Query: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
RRPLILQL+ E +FLH K+K +TDFDE+RQEIE ET+R++
Sbjct: 66 RRPLILQLIFSKTEH----------------AEFLHCKSKKFTDFDEVRQEIEAETDRVT 109
Query: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
G NKG+SP PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QI+++IL+FIS +S
Sbjct: 110 GTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESS 169
Query: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
+ILAVT AN D+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 170 LILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
Query: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
G IGVVNRSQ DI KK + ++ E F Y +A+R GT +L +TLN+ L +HI
Sbjct: 230 GYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHI 289
Query: 298 RDCLPELKTRIN----VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAK 353
R+ LP L++++ L + + N + K+ LLQ++ +F ++ IEG+
Sbjct: 290 RESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGD 349
Query: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
++T EL GGARI IFHE F L ++ +I AI+N G R LF P+++F
Sbjct: 350 QVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAF 409
Query: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
E +VK+Q+ +L+EP L+CV+LV +E+ ++ C T +L +P+L + +VT +R
Sbjct: 410 EAIVKKQVVKLKEPCLKCVDLVIQELINTVRQC----TSKLSSYPRLREETERIVTTYIR 465
Query: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSR 530
+R T + + L+ IE +YINT H DF G N + N+ R +P+ V R
Sbjct: 466 EREGRTKDQILLLIDIEQSYINTNHEDF---IGFANAQQRSTQLNK-KRAIPNQVIR 518
Score = 72.0 bits (175), Expect = 2e-12
Identities = 36/90 (40%), Positives = 53/90 (58%)
Query: 615 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674
+R E I L+ SY I+ K+I+D +PK +MH ++N+ K + EL+ LY S+ L+
Sbjct: 646 ERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLM 705
Query: 675 TESEDMAQRRKEAADMLKALQGASQIIAEI 704
ES D AQRR + M AL+ A II +I
Sbjct: 706 EESADQAQRRDDMLRMYHALKEALNIIGDI 735
>gi|56549121 dynamin 2 isoform 1 [Homo sapiens]
Length = 870
Score = 448 bits (1153), Expect = e-126
Identities = 242/508 (47%), Positives = 340/508 (66%), Gaps = 27/508 (5%)
Query: 1 MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
ME LIP++NKLQD F+++G + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 6 MEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
Query: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
RRPLILQL+ E +FLH K+K +TDFDE+RQEIE ET+R++
Sbjct: 66 RRPLILQLIFSKTEH----------------AEFLHCKSKKFTDFDEVRQEIEAETDRVT 109
Query: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
G NKG+SP PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QI+++IL+FIS +S
Sbjct: 110 GTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESS 169
Query: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
+ILAVT AN D+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 170 LILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
Query: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
G IGVVNRSQ DI KK + ++ E F Y +A+R GT +L +TLN+ L +HI
Sbjct: 230 GYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHI 289
Query: 298 RDCLPELKTRIN----VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAK 353
R+ LP L++++ L + + N + K+ LLQ++ +F ++ IEG+
Sbjct: 290 RESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGD 349
Query: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
++T EL GGARI IFHE F L ++ +I AI+N G R LF P+++F
Sbjct: 350 QVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAF 409
Query: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
E +VK+Q+ +L+EP L+CV+LV +E+ ++ C T +L +P+L + +VT +R
Sbjct: 410 EAIVKKQVVKLKEPCLKCVDLVIQELINTVRQC----TSKLSSYPRLREETERIVTTYIR 465
Query: 474 KRLPVTNEMVHNLVAIELAYINTKHPDF 501
+R T + + L+ IE +YINT H DF
Sbjct: 466 EREGRTKDQILLLIDIEQSYINTNHEDF 493
Score = 72.0 bits (175), Expect = 2e-12
Identities = 36/90 (40%), Positives = 53/90 (58%)
Query: 615 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674
+R E I L+ SY I+ K+I+D +PK +MH ++N+ K + EL+ LY S+ L+
Sbjct: 650 ERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLM 709
Query: 675 TESEDMAQRRKEAADMLKALQGASQIIAEI 704
ES D AQRR + M AL+ A II +I
Sbjct: 710 EESADQAQRRDDMLRMYHALKEALNIIGDI 739
>gi|42544243 dynamin 3 isoform a [Homo sapiens]
Length = 863
Score = 437 bits (1125), Expect = e-122
Identities = 238/531 (44%), Positives = 349/531 (65%), Gaps = 27/531 (5%)
Query: 1 MEALIPVINKLQDVFNTVGAD-IIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
ME LIP++N+LQD F+ +G +++LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 6 MEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
Query: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
RRPL+LQLV E+ +FLH K K +TDFDE+R EIE ET+R++
Sbjct: 66 RRPLVLQLV----------------TSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVT 109
Query: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
G NKG+S PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QIRE+I++FI+ N
Sbjct: 110 GMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENC 169
Query: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
+ILAVT ANTD+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 170 LILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
Query: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
G +GVVNRSQ DI+ KK + ++ E F Y +A+R GT +L + LN+ L +HI
Sbjct: 230 GYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHI 289
Query: 298 RDCLPELKTRI--NVLAAQYQSLLNSYGEPVDD--KSATLLQLITKFATEYCNTIEGTAK 353
RD LP + ++ +L+ +++ +P D K+ LLQ++ +FA ++ IEG+
Sbjct: 290 RDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGD 349
Query: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
++T EL GGA+I IFHE F + ++ +I AI+N G R LF P+++F
Sbjct: 350 QVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAF 409
Query: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
E +VK+QI +L+ PSL+ V+LV +E+ ++ C T++L FP+L + +V +R
Sbjct: 410 EAIVKKQIVKLKGPSLKSVDLVIQELINTVKKC----TKKLANFPRLCEETERIVANHIR 465
Query: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLAREL 524
+R T + V L+ I+++YINT H DF + + ++ + ++
Sbjct: 466 EREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQV 516
Score = 79.3 bits (194), Expect = 1e-14
Identities = 40/90 (44%), Positives = 57/90 (63%)
Query: 615 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674
+R E I L+ SY I+ K I+D +PK +MH ++N+VKD + SEL+ QLY S + L+
Sbjct: 650 ERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLM 709
Query: 675 TESEDMAQRRKEAADMLKALQGASQIIAEI 704
ES + AQRR E M +AL+ A II +I
Sbjct: 710 EESAEQAQRRDEMLRMYQALKEALGIIGDI 739
>gi|209915561 dynamin 3 isoform b [Homo sapiens]
Length = 859
Score = 437 bits (1125), Expect = e-122
Identities = 238/531 (44%), Positives = 349/531 (65%), Gaps = 27/531 (5%)
Query: 1 MEALIPVINKLQDVFNTVGAD-IIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
ME LIP++N+LQD F+ +G +++LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 6 MEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
Query: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
RRPL+LQLV E+ +FLH K K +TDFDE+R EIE ET+R++
Sbjct: 66 RRPLVLQLV----------------TSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVT 109
Query: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
G NKG+S PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QIRE+I++FI+ N
Sbjct: 110 GMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENC 169
Query: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
+ILAVT ANTD+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 170 LILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
Query: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
G +GVVNRSQ DI+ KK + ++ E F Y +A+R GT +L + LN+ L +HI
Sbjct: 230 GYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHI 289
Query: 298 RDCLPELKTRI--NVLAAQYQSLLNSYGEPVDD--KSATLLQLITKFATEYCNTIEGTAK 353
RD LP + ++ +L+ +++ +P D K+ LLQ++ +FA ++ IEG+
Sbjct: 290 RDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGD 349
Query: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
++T EL GGA+I IFHE F + ++ +I AI+N G R LF P+++F
Sbjct: 350 QVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAF 409
Query: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
E +VK+QI +L+ PSL+ V+LV +E+ ++ C T++L FP+L + +V +R
Sbjct: 410 EAIVKKQIVKLKGPSLKSVDLVIQELINTVKKC----TKKLANFPRLCEETERIVANHIR 465
Query: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLAREL 524
+R T + V L+ I+++YINT H DF + + ++ + ++
Sbjct: 466 EREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQV 516
Score = 79.3 bits (194), Expect = 1e-14
Identities = 40/90 (44%), Positives = 57/90 (63%)
Query: 615 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674
+R E I L+ SY I+ K I+D +PK +MH ++N+VKD + SEL+ QLY S + L+
Sbjct: 646 ERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLM 705
Query: 675 TESEDMAQRRKEAADMLKALQGASQIIAEI 704
ES + AQRR E M +AL+ A II +I
Sbjct: 706 EESAEQAQRRDEMLRMYQALKEALGIIGDI 735
>gi|11342664 myxovirus resistance protein 2 [Homo sapiens]
Length = 715
Score = 196 bits (497), Expect = 8e-50
Identities = 151/473 (31%), Positives = 241/473 (50%), Gaps = 32/473 (6%)
Query: 23 IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTRRPLILQLVHVSQEDKRKTTGEE 82
+ LP I V+G QSSGKSSVLE+L G LPRG+GIVTR PL+L+L K++
Sbjct: 116 LALPAIAVIGDQSSGKSSVLEALSGV-ALPRGSGIVTRCPLVLKL-------KKQP---- 163
Query: 83 NGVEAEEW-GKFLHTKNKL-YTDFDEIRQEIENETERISGNNKGVSPEPIHLKIFSPNVV 140
E W G+ + +L D ++ +EI ++GN +G+S E I L+I SP V
Sbjct: 164 ----CEAWAGRISYRNTELELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEVP 219
Query: 141 NLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSEALKIS 200
+LT++DLPG+T+V V +QP+DI LQI+ LI ++I +I L V N D+AT+EAL ++
Sbjct: 220 DLTIIDLPGITRVAVDNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEALSMA 279
Query: 201 REVDPDGRRTLAVITKLDLMDAGTD--AMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSV 258
EVDP+G RT+ ++TK DLMD GT+ M+V+ P+K G + V R Q +I N+ S+
Sbjct: 280 HEVDPEGDRTIGILTKPDLMDRGTEKSVMNVVRNLTYPLKKGYMIVKCRGQQEITNRLSL 339
Query: 259 TDSIRDEYAFLQ-KKYPSLANRNGTKYLARTLNRL---LMHHIRDCLPELKTRINVLAAQ 314
++ + E F Q Y + G+ + R RL L+ HI+ LP L+ +I +
Sbjct: 340 AEATKKEITFFQTHPYFRVLLEEGSATVPRLAERLTTELIMHIQKSLPLLEGQIRESHQK 399
Query: 315 YQSLLNSYGEPVD----DKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIF 370
L G + DK L++ I F + +EG + + +E +I F
Sbjct: 400 ATEELRRCGADIPSQEADKMFFLIEKIKMFNQDIEKLVEG-EEVVRENETRLYNKIREDF 458
Query: 371 HETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLR 430
G + + + ++ + G FV +FE++V + I++L EP+L
Sbjct: 459 KNWVGILATNTQKVKNIIHEEVEKYEKQYRGKELLGFVNYKTFEIIVHQYIQQLVEPAL- 517
Query: 431 CVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMV 483
++ + M+ I Q N + + F L+ + + + K M+
Sbjct: 518 --SMLQKAMEIIQQAFINVAKKHFGEFFNLNQTVQSTIEDIKVKHTAKAENMI 568
Score = 34.3 bits (77), Expect = 0.41
Identities = 19/86 (22%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Query: 625 IKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRR 684
+ +YFL K + + +P + +F++ D+LQ ++ L + + LL E + A +R
Sbjct: 630 LNAYFLETSKRLANQIPFIIQYFMLRENGDSLQKAMMQILQEKNRYSWLLQEQSETATKR 689
Query: 685 KEAADMLKALQGASQIIAEI--RETH 708
+ + + L A + + +E H
Sbjct: 690 RILKERIYRLTQARHALCQFSSKEIH 715
>gi|222136619 myxovirus resistance protein 1 [Homo sapiens]
Length = 662
Score = 195 bits (495), Expect = 1e-49
Identities = 149/451 (33%), Positives = 236/451 (52%), Gaps = 31/451 (6%)
Query: 23 IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTRRPLILQLVHVSQEDKRKTTGEE 82
+ LP I V+G QSSGKSSVLE+L G LPRG+GIVTR PL+L+L + EDK +
Sbjct: 68 LALPAIAVIGDQSSGKSSVLEALSGV-ALPRGSGIVTRCPLVLKLKKLVNEDKWRGKVSY 126
Query: 83 NGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISGNNKGVSPEPIHLKIFSPNVVNL 142
E E +D E+ +EI I+G G+S E I L+I S +V +L
Sbjct: 127 QDYEIE------------ISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDL 174
Query: 143 TLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSEALKISRE 202
TL+DLPG+T+V VG+QP DI +I+ LI ++I +I L V +N D+AT+EAL +++E
Sbjct: 175 TLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQE 234
Query: 203 VDPDGRRTLAVITKLDLMDAGTD--AMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTD 260
VDP+G RT+ ++TK DL+D GT+ +DV+ V +K G + V R Q +I ++ S+++
Sbjct: 235 VDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSE 294
Query: 261 SIRDEYAFLQKKYPSLAN-----RNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQY 315
+++ E F + +P + + LA L L+ HI LP L+ +I +
Sbjct: 295 ALQREKIFFEN-HPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRI 353
Query: 316 QSLLNSYG----EPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFH 371
L YG E ++K L+ + F + ++G + + ++ R+ + FH
Sbjct: 354 TEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGE-ETVGEEDIRLFTRLRHEFH 412
Query: 372 ETFGRTLESVDPLGGLNTIDILTAIRNA-TGPRPALFVPEVSFELLVKRQIKRLEEPSLR 430
+ + +E+ G + N G FV +FE +VK+QIK LEEP+
Sbjct: 413 K-WSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPA-- 469
Query: 431 CVELVHEEMQRIIQHCSNYSTQELLRFPKLH 461
V+++H + ++ S + F LH
Sbjct: 470 -VDMLHTVTDMVRLAFTDVSIKNFEEFFNLH 499
>gi|222136617 myxovirus resistance protein 1 [Homo sapiens]
Length = 662
Score = 195 bits (495), Expect = 1e-49
Identities = 149/451 (33%), Positives = 236/451 (52%), Gaps = 31/451 (6%)
Query: 23 IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTRRPLILQLVHVSQEDKRKTTGEE 82
+ LP I V+G QSSGKSSVLE+L G LPRG+GIVTR PL+L+L + EDK +
Sbjct: 68 LALPAIAVIGDQSSGKSSVLEALSGV-ALPRGSGIVTRCPLVLKLKKLVNEDKWRGKVSY 126
Query: 83 NGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISGNNKGVSPEPIHLKIFSPNVVNL 142
E E +D E+ +EI I+G G+S E I L+I S +V +L
Sbjct: 127 QDYEIE------------ISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDL 174
Query: 143 TLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSEALKISRE 202
TL+DLPG+T+V VG+QP DI +I+ LI ++I +I L V +N D+AT+EAL +++E
Sbjct: 175 TLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQE 234
Query: 203 VDPDGRRTLAVITKLDLMDAGTD--AMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTD 260
VDP+G RT+ ++TK DL+D GT+ +DV+ V +K G + V R Q +I ++ S+++
Sbjct: 235 VDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSE 294
Query: 261 SIRDEYAFLQKKYPSLAN-----RNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQY 315
+++ E F + +P + + LA L L+ HI LP L+ +I +
Sbjct: 295 ALQREKIFFEN-HPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRI 353
Query: 316 QSLLNSYG----EPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFH 371
L YG E ++K L+ + F + ++G + + ++ R+ + FH
Sbjct: 354 TEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGE-ETVGEEDIRLFTRLRHEFH 412
Query: 372 ETFGRTLESVDPLGGLNTIDILTAIRNA-TGPRPALFVPEVSFELLVKRQIKRLEEPSLR 430
+ + +E+ G + N G FV +FE +VK+QIK LEEP+
Sbjct: 413 K-WSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPA-- 469
Query: 431 CVELVHEEMQRIIQHCSNYSTQELLRFPKLH 461
V+++H + ++ S + F LH
Sbjct: 470 -VDMLHTVTDMVRLAFTDVSIKNFEEFFNLH 499
>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
Length = 1015
Score = 104 bits (260), Expect = 2e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 317 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 376
Query: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 377 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 420
Query: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 421 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 480
Query: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 481 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 540
Query: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 541 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 579
>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
Length = 997
Score = 104 bits (260), Expect = 2e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
Query: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 359 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 402
Query: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 403 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 462
Query: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 463 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 522
Query: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 523 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 561
>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
Length = 979
Score = 104 bits (260), Expect = 2e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
Query: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 341 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 384
Query: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 385 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 444
Query: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 445 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 504
Query: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 505 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 543
>gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]
Length = 978
Score = 104 bits (260), Expect = 2e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339
Query: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 340 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 383
Query: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 384 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 443
Query: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 444 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 503
Query: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 504 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 542
>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
Length = 961
Score = 104 bits (260), Expect = 2e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
Query: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 323 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 366
Query: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 367 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 426
Query: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 427 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 486
Query: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 487 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 525
>gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]
Length = 942
Score = 104 bits (260), Expect = 2e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 244 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 303
Query: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 304 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 347
Query: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 348 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 407
Query: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 408 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 467
Query: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 468 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 506
>gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]
Length = 924
Score = 104 bits (260), Expect = 2e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 226 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 285
Query: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 286 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 329
Query: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 330 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 389
Query: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 390 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 449
Query: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 450 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 488
>gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]
Length = 960
Score = 104 bits (260), Expect = 2e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 262 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 321
Query: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 322 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 365
Query: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 366 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 425
Query: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 426 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 485
Query: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 486 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 524
>gi|239756350 PREDICTED: UPF0621 protein C-like [Homo sapiens]
Length = 135
Score = 48.9 bits (115), Expect = 2e-05
Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 619 EVIERLIKSYFLIVRKNIQDSV----PKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674
E + L+ SY IV K + D + PK MH ++N++ + + SEL+ +LY + L+
Sbjct: 33 ETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHLMINNMHEFIFSELLAKLYSCGDENMLM 92
Query: 675 TESEDMAQRRKEAADMLKALQGASQIIAEIRET 707
+S + A+ E M L+ A II +I+ T
Sbjct: 93 EDSTEQAKWCNETLCMHHVLREAPNIIGDIKTT 125
>gi|239750876 PREDICTED: UPF0621 protein C-like [Homo sapiens]
Length = 135
Score = 48.9 bits (115), Expect = 2e-05
Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 619 EVIERLIKSYFLIVRKNIQDSV----PKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674
E + L+ SY IV K + D + PK MH ++N++ + + SEL+ +LY + L+
Sbjct: 33 ETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHLMINNMHEFIFSELLAKLYSCGDENMLM 92
Query: 675 TESEDMAQRRKEAADMLKALQGASQIIAEIRET 707
+S + A+ E M L+ A II +I+ T
Sbjct: 93 EDSTEQAKWCNETLCMHHVLREAPNIIGDIKTT 125
>gi|169208224 PREDICTED: UPF0621 protein C-like [Homo sapiens]
Length = 155
Score = 48.9 bits (115), Expect = 2e-05
Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 619 EVIERLIKSYFLIVRKNIQDSV----PKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674
E + L+ SY IV K + D + PK MH ++N++ + + SEL+ +LY + L+
Sbjct: 53 ETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHLMINNMHEFIFSELLAKLYSCGDENMLM 112
Query: 675 TESEDMAQRRKEAADMLKALQGASQIIAEIRET 707
+S + A+ E M L+ A II +I+ T
Sbjct: 113 EDSTEQAKWCNETLCMHHVLREAPNIIGDIKTT 145
>gi|27262622 neuron navigator 1 [Homo sapiens]
Length = 1874
Score = 33.9 bits (76), Expect = 0.54
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 106 EIRQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQ 165
++R+E+E+ E+++ +S + F ++VN+T + + + KD EL
Sbjct: 1085 KLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMT----SRLRHLAETAEEKDTELL 1140
Query: 166 IRELILRFISNPNSIILAVT--AANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAG 223
+ F+ NS AV A N T + L+I R+ D +L IT + +
Sbjct: 1141 DLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSS 1200
Query: 224 TDA 226
DA
Sbjct: 1201 KDA 1203
>gi|148746220 spermatogenesis associated, serine-rich 2 [Homo
sapiens]
Length = 545
Score = 32.7 bits (73), Expect = 1.2
Identities = 28/126 (22%), Positives = 63/126 (50%), Gaps = 13/126 (10%)
Query: 588 PASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKS---YFLIVRKNIQDSVPKAV 644
P + + + + DVP+ ++KLS+ ++ + ++R S Y ++V++ + S+ K
Sbjct: 212 PTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMK 271
Query: 645 MHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLK-----ALQGASQ 699
F ++ L V L + +D + E+ ++ R++ A++LK A+Q + Q
Sbjct: 272 QAFA--ELESCLMDREVALLAE---MDKVKAEAMEILLSRQKKAELLKKMTHVAVQMSEQ 326
Query: 700 IIAEIR 705
+ E+R
Sbjct: 327 QLVELR 332
>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 32.3 bits (72), Expect = 1.6
Identities = 16/31 (51%), Positives = 18/31 (58%)
Query: 275 SLANRNGTKYLARTLNRLLMHHIRDCLPELK 305
S NR GT+YL RT NRL D LP+ K
Sbjct: 75 SEVNRTGTQYLLRTANRLFGEKTCDFLPDFK 105
>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 32.3 bits (72), Expect = 1.6
Identities = 16/31 (51%), Positives = 18/31 (58%)
Query: 275 SLANRNGTKYLARTLNRLLMHHIRDCLPELK 305
S NR GT+YL RT NRL D LP+ K
Sbjct: 75 SEVNRTGTQYLLRTANRLFGEKTCDFLPDFK 105
>gi|73623033 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform b [Homo sapiens]
Length = 242
Score = 32.3 bits (72), Expect = 1.6
Identities = 16/31 (51%), Positives = 18/31 (58%)
Query: 275 SLANRNGTKYLARTLNRLLMHHIRDCLPELK 305
S NR GT+YL RT NRL D LP+ K
Sbjct: 75 SEVNRTGTQYLLRTANRLFGEKTCDFLPDFK 105
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,883,596
Number of Sequences: 37866
Number of extensions: 1124256
Number of successful extensions: 3764
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 3651
Number of HSP's gapped (non-prelim): 67
length of query: 710
length of database: 18,247,518
effective HSP length: 109
effective length of query: 601
effective length of database: 14,120,124
effective search space: 8486194524
effective search space used: 8486194524
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.