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Search of human proteins with 16933528
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16933528 cytochrome P450, family 26, subfamily A,
polypeptide 1 isoform 2 [Homo sapiens]
(428 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16933528 cytochrome P450, family 26, subfamily A, polypeptide... 872 0.0
gi|16933530 cytochrome P450, family 26, subfamily A, polypeptide... 872 0.0
gi|9845285 cytochrome P450, family 26, subfamily b, polypeptide ... 354 7e-98
gi|62952502 cytochrome P450, family 26, subfamily C, polypeptide... 347 2e-95
gi|187960086 cytochrome P450, family 4, subfamily v, polypeptide... 115 8e-26
gi|158937242 cytochrome P450, family 4, subfamily A, polypeptide... 110 3e-24
gi|62952506 cytochrome P450, family 4, subfamily A, polypeptide ... 109 4e-24
gi|4503243 cytochrome P450, family 51, subfamily A, polypeptide ... 108 9e-24
gi|225903399 cytochrome P450, family 51, subfamily A, polypeptid... 103 3e-22
gi|119220562 cytochrome P450, family 4, subfamily F, polypeptide... 102 9e-22
gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11... 100 4e-21
gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11... 100 4e-21
gi|13435391 cytochrome P450, family 4, subfamily F, polypeptide ... 97 2e-20
gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide... 97 3e-20
gi|158138530 cytochrome P450, family 4, subfamily F, polypeptide... 96 8e-20
gi|5729796 cytochrome P450, family 46 [Homo sapiens] 95 1e-19
gi|29837648 cytochrome P450, family 4, subfamily X, polypeptide ... 95 1e-19
gi|153218660 cytochrome P450, family 4, subfamily B, polypeptide... 94 2e-19
gi|16933533 cytochrome P450, family 3, subfamily A, polypeptide ... 94 3e-19
gi|4503233 cytochrome P450, family 3, subfamily A, polypeptide 7... 92 7e-19
gi|6005737 cytochrome P450, family 4, subfamily F, polypeptide 8... 92 9e-19
gi|153218662 cytochrome P450, family 4, subfamily B, polypeptide... 91 2e-18
gi|30023836 cytochrome P450 4Z1 [Homo sapiens] 91 3e-18
gi|13435386 cytochrome P450, family 3, subfamily A, polypeptide ... 90 3e-18
gi|12383060 cytochrome P450, family 3, subfamily A, polypeptide ... 89 8e-18
gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5... 87 2e-17
gi|55770850 cytochrome P450 family 24 subfamily A polypeptide 1 ... 86 8e-17
gi|167466231 cytochrome P450, family 27, subfamily C, polypeptid... 86 8e-17
gi|13449277 cytochrome P450, family 2, subfamily S, polypeptide ... 82 7e-16
gi|4503213 cytochrome P450, family 27, subfamily B, polypeptide ... 81 2e-15
>gi|16933528 cytochrome P450, family 26, subfamily A, polypeptide 1
isoform 2 [Homo sapiens]
Length = 428
Score = 872 bits (2252), Expect = 0.0
Identities = 428/428 (100%), Positives = 428/428 (100%)
Query: 1 MKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLH 60
MKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLH
Sbjct: 1 MKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLH 60
Query: 61 DSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIA 120
DSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIA
Sbjct: 61 DSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIA 120
Query: 121 MRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQ 180
MRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQ
Sbjct: 121 MRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQ 180
Query: 181 NIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAA 240
NIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAA
Sbjct: 181 NIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAA 240
Query: 241 TSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPP 300
TSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPP
Sbjct: 241 TSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPP 300
Query: 301 VPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASR 360
VPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASR
Sbjct: 301 VPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASR 360
Query: 361 FSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPAR 420
FSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPAR
Sbjct: 361 FSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPAR 420
Query: 421 FTHFHGEI 428
FTHFHGEI
Sbjct: 421 FTHFHGEI 428
>gi|16933530 cytochrome P450, family 26, subfamily A, polypeptide 1
isoform 1 [Homo sapiens]
Length = 497
Score = 872 bits (2252), Expect = 0.0
Identities = 428/428 (100%), Positives = 428/428 (100%)
Query: 1 MKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLH 60
MKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLH
Sbjct: 70 MKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLH 129
Query: 61 DSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIA 120
DSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIA
Sbjct: 130 DSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIA 189
Query: 121 MRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQ 180
MRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQ
Sbjct: 190 MRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQ 249
Query: 181 NIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAA 240
NIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAA
Sbjct: 250 NIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAA 309
Query: 241 TSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPP 300
TSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPP
Sbjct: 310 TSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPP 369
Query: 301 VPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASR 360
VPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASR
Sbjct: 370 VPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASR 429
Query: 361 FSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPAR 420
FSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPAR
Sbjct: 430 FSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPAR 489
Query: 421 FTHFHGEI 428
FTHFHGEI
Sbjct: 490 FTHFHGEI 497
>gi|9845285 cytochrome P450, family 26, subfamily b, polypeptide 1
[Homo sapiens]
Length = 512
Score = 354 bits (909), Expect = 7e-98
Identities = 189/424 (44%), Positives = 269/424 (63%), Gaps = 13/424 (3%)
Query: 2 KRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHD 61
+R KYG ++KTHL GRP +RV GA+NVR+IL+GEH LVS WP S R +LG +SN
Sbjct: 76 RREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGPNTVSNSIG 135
Query: 62 SSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAM 121
H+ ++KV + FS EALE Y+P I + +L W S E + VY E ++L FR+A+
Sbjct: 136 DIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPE-AINVYQEAQKLTFRMAI 194
Query: 122 RILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQN 181
R+LLG + + L E +++ N+FSLP+D+PFSG RG++AR ++ +E+
Sbjct: 195 RVLLG----FSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRRGIQARQILQKGLEKA 250
Query: 182 IRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAAT 241
IR K+ G+ DAL LLIE S E G+ + MQ LK + EL+F + TTASA+T
Sbjct: 251 IREKL----QCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASAST 306
Query: 242 SLITYLGLYPHVLQKVREELKSKGLLCKSN--QDNKLDMEILEQLKYIGCVIKETLRLNP 299
SLI L +P VL+K+R+EL++ G+L + L ++ L L+Y+ CVIKE +RL
Sbjct: 307 SLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFT 366
Query: 300 PVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDA- 358
P+ GG+R L+TFEL+G+QIPKGW+V+YSI DTHD A +F + F+PDRF ED
Sbjct: 367 PISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKD 426
Query: 359 SRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGP-PTMKTSPTVYPVDNL 417
RF ++PFGGG+R+C+GK AK+ LK+ VELA ++L P + P ++PVD L
Sbjct: 427 GRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVLHPVDGL 486
Query: 418 PARF 421
+F
Sbjct: 487 SVKF 490
>gi|62952502 cytochrome P450, family 26, subfamily C, polypeptide 1
[Homo sapiens]
Length = 522
Score = 347 bits (889), Expect = 2e-95
Identities = 199/440 (45%), Positives = 267/440 (60%), Gaps = 35/440 (7%)
Query: 2 KRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHD 61
+R +YG ++KTHL GRP +RV GA+NVR ILLGEHRLV WP S +LGS L
Sbjct: 76 RRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVG 135
Query: 62 SSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAM 121
H++R+KV+ R FSR ALE YVP + + + W + G + VY K L FR+A
Sbjct: 136 EPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCAAG-GPVSVYDASKALTFRMAA 194
Query: 122 RILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQN 181
RILLG L D L FE++ NLFSLP+DVPFSGL +G++AR+ +H +E
Sbjct: 195 RILLG----LRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLRKGIRARDQLHRHLEGA 250
Query: 182 IRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAAT 241
I K+ +A+E G DAL L+I + E G MQ LK+S+ ELLF TTASA+T
Sbjct: 251 ISEKLHEDKAAEPG----DALDLIIHSARELGHEPSMQELKESAVELLFAAFFTTASAST 306
Query: 242 SLITYLGLYPHVLQKVREELKSKGL-------------------LCKSNQDNKLDMEILE 282
SL+ L +P + K+REEL ++GL C D L + L
Sbjct: 307 SLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPD--LSLAALG 364
Query: 283 QLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNK 342
+L+Y+ CV+KE LRL PPV GG+R AL+TFEL+GYQIPKGW+V+YSI DTH+ A ++ +
Sbjct: 365 RLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSP 424
Query: 343 EE-FNPDRFMLPHPED---ASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQL 398
E F+P+RF + +SRF +IPFGGG RSC+G+E A+ +L++ VEL R W+L
Sbjct: 425 PEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWEL 484
Query: 399 LNGP-PTMKTSPTVYPVDNL 417
P M+T P V+PVD L
Sbjct: 485 ATPAFPAMQTVPIVHPVDGL 504
>gi|187960086 cytochrome P450, family 4, subfamily v, polypeptide 2
[Homo sapiens]
Length = 525
Score = 115 bits (288), Expect = 8e-26
Identities = 104/405 (25%), Positives = 176/405 (43%), Gaps = 44/405 (10%)
Query: 18 PTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSR 77
P V + A+NV IL ++ + LG G L++ + + R+K++ F
Sbjct: 98 PMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTST-GNKWRSRRKMLTPTFHF 156
Query: 78 EALECYVPVITEEVG---SSLEQWLSCGERGLLVYPEVKRLMFRIAMRIL-LGCEP---- 129
LE ++ ++ E+ LE+ ++ E F I + L + CE
Sbjct: 157 TILEDFLDIMNEQANILVKKLEKHIN---------QEAFNCFFYITLCALDIICETAMGK 207
Query: 130 QLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGL----------YRGMKARNLIHARIE 179
+ + + + V A M+ +F I +P+ L + K+ ++H
Sbjct: 208 NIGAQSNDDSEYVRAVYRMSEMIFRR-IKMPWLWLDLWYLMFKEGWEHKKSLQILHTFTN 266
Query: 180 QNIRAKICGLRASE--AGQGCKDA---------LQLLIEHSWERGERLDMQALKQSSTEL 228
I + + A+E G G A L LL+ + + G RL + +++
Sbjct: 267 SVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTF 326
Query: 229 LFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIG 288
+F GH+TTA+A + LG P V +KV EL D +E L++L+Y+
Sbjct: 327 MFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDD----VFGKSDRPATVEDLKKLRYLE 382
Query: 289 CVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPD 348
CVIKETLRL P VP R + E+ GY++ KG + H F N EEF P+
Sbjct: 383 CVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPE 442
Query: 349 RFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 393
RF + + ++++PF G R+C+G++FA + K + RH
Sbjct: 443 RFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRH 487
>gi|158937242 cytochrome P450, family 4, subfamily A, polypeptide 11
[Homo sapiens]
Length = 519
Score = 110 bits (274), Expect = 3e-24
Identities = 101/355 (28%), Positives = 165/355 (46%), Gaps = 28/355 (7%)
Query: 51 LGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQW--LSCGERGLLV 108
+G G L L+ + Q ++++ AF + L+ YV ++ + V L++W L + L V
Sbjct: 127 IGYGLLL-LNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEV 185
Query: 109 YPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSL------PIDVPFS 162
+ V + M+ + + D +S Q ++A ++ +FS D +S
Sbjct: 186 FQHVSLMTLDTIMKCAFSHQGSIQVDRNS-QSYIQAISDLNNLVFSRVRNAFHQNDTIYS 244
Query: 163 GLYRGM---KARNLIHARIEQNIRAKICGLRASEAGQGCK-----DALQLLIEHSWERGE 214
G +A L H +Q I+ + L+ + K D L +L+ E G
Sbjct: 245 LTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAKMENGS 304
Query: 215 RLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDN 274
L + L+ +F GH+TTAS + ++ L +P ++ REE+ S LL
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHS--LL---GDGA 359
Query: 275 KLDMEILEQLKYIGCVIKETLRLNPPVPG-GFRVALKTFELNGYQIPKGWNVIYSICDTH 333
+ L+Q+ Y IKE LRL PPVPG G ++ +G +PKG V+ SI H
Sbjct: 360 SITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLH 419
Query: 334 DVAEIFTNKEEFNPDRFMLPHPEDASR-FSFIPFGGGLRSCVGKEFAKILLKIFT 387
+++ N E F+P RF P A +F+PF GG R+C+GK+FA LK+ T
Sbjct: 420 HNPKVWPNPEVFDPFRFA---PGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVAT 471
>gi|62952506 cytochrome P450, family 4, subfamily A, polypeptide 22
[Homo sapiens]
Length = 519
Score = 109 bits (273), Expect = 4e-24
Identities = 101/354 (28%), Positives = 164/354 (46%), Gaps = 30/354 (8%)
Query: 51 LGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQW--LSCGERGLLV 108
+G G L L+ + Q ++++ AF + L+ YV ++ + V L++W L + L V
Sbjct: 127 IGYGLLL-LNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEV 185
Query: 109 YPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMT-------RNLFSLPIDVPF 161
+ V + M+ + + D +S Q ++A ++ RN F D +
Sbjct: 186 FQHVSLMTLDTIMKSAFSHQGSIQVDRNS-QSYIQAISDLNSLVFCCMRNAFH-ENDTIY 243
Query: 162 SGLYRGM---KARNLIHARIEQNIRAKICGLRASEAGQGCK-----DALQLLIEHSWERG 213
S G +A L H +Q I+ + L+ + K D L +L+ E G
Sbjct: 244 SLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAKMENG 303
Query: 214 ERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQD 273
L + L+ +F GH+TTAS + ++ L +P ++ REE+ GLL
Sbjct: 304 SILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEI--HGLL---GDG 358
Query: 274 NKLDMEILEQLKYIGCVIKETLRLNPPVPG-GFRVALKTFELNGYQIPKGWNVIYSICDT 332
+ L+Q+ Y IKE LRL PPVPG G ++ +G +PKG V+ SI
Sbjct: 359 ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGL 418
Query: 333 HDVAEIFTNKEEFNPDRFMLPHPEDASR-FSFIPFGGGLRSCVGKEFAKILLKI 385
H +++ N E F+P RF P A +F+PF GG R+C+GK+FA LK+
Sbjct: 419 HHNPKVWPNLEVFDPSRFA---PGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKV 469
>gi|4503243 cytochrome P450, family 51, subfamily A, polypeptide 1
isoform 1 [Homo sapiens]
Length = 509
Score = 108 bits (270), Expect = 9e-24
Identities = 96/420 (22%), Positives = 184/420 (43%), Gaps = 15/420 (3%)
Query: 5 KYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRT--ILGSGCLSNLHDS 62
KYG ++ + G+ ++G+D + ++ ++ S T + G G ++ +
Sbjct: 97 KYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNP 156
Query: 63 SHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMR 122
++KK++ + + +V +I +E E W GE+ V+ + L+ A
Sbjct: 157 VFLEQKKMLKSGLNIAHFKQHVSIIEKETKEYFESWGESGEKN--VFEALSELIILTASH 214
Query: 123 ILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNI 182
L G E + + Q + + + LP +P R R+ H I+
Sbjct: 215 CLHGKEIRSQLNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRR----RDRAHREIKDIF 270
Query: 183 RAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATS 242
I R S+ + D LQ L++ +++ G L + LL G T+++ +
Sbjct: 271 YKAIQKRRQSQ--EKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAW 328
Query: 243 LITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVP 302
+ +L + +K E K+ +C N L + L+ L + IKETLRL PP+
Sbjct: 329 MGFFLARDKTLQKKCYLEQKT---VCGENLP-PLTYDQLKDLNLLDRCIKETLRLRPPIM 384
Query: 303 GGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFS 362
R+A + GY IP G V S + + + + +FNPDR++ +P +F+
Sbjct: 385 IMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFA 444
Query: 363 FIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGP-PTMKTSPTVYPVDNLPARF 421
++PFG G C+G+ FA + +K + R ++ L++G PT+ + ++ +N R+
Sbjct: 445 YVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPVIRY 504
>gi|225903399 cytochrome P450, family 51, subfamily A, polypeptide 1
isoform 2 [Homo sapiens]
Length = 404
Score = 103 bits (257), Expect = 3e-22
Identities = 88/373 (23%), Positives = 164/373 (43%), Gaps = 13/373 (3%)
Query: 50 ILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVY 109
+ G G ++ + ++KK++ + + +V +I +E E W GE+ V+
Sbjct: 39 VFGKGVAYDVPNPVFLEQKKMLKSGLNIAHFKQHVSIIEKETKEYFESWGESGEKN--VF 96
Query: 110 PEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMK 169
+ L+ A L G E + + Q + + + LP +P R
Sbjct: 97 EALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRR--- 153
Query: 170 ARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELL 229
R+ H I+ I R S+ + D LQ L++ +++ G L + LL
Sbjct: 154 -RDRAHREIKDIFYKAIQKRRQSQ--EKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLL 210
Query: 230 FGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGC 289
G T+++ + + +L + +K E K+ +C N L + L+ L +
Sbjct: 211 LAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKT---VCGENLP-PLTYDQLKDLNLLDR 266
Query: 290 VIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDR 349
IKETLRL PP+ R+A + GY IP G V S + + + + +FNPDR
Sbjct: 267 CIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDR 326
Query: 350 FMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGP-PTMKTS 408
++ +P +F+++PFG G C+G+ FA + +K + R ++ L++G PT+ +
Sbjct: 327 YLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYT 386
Query: 409 PTVYPVDNLPARF 421
++ +N R+
Sbjct: 387 TMIHTPENPVIRY 399
>gi|119220562 cytochrome P450, family 4, subfamily F, polypeptide 3
[Homo sapiens]
Length = 520
Score = 102 bits (253), Expect = 9e-22
Identities = 57/187 (30%), Positives = 105/187 (56%), Gaps = 4/187 (2%)
Query: 200 DALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVRE 259
D + +L+ E G++L + ++ + +F GH+TTAS + ++ +L +P ++ R+
Sbjct: 297 DFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQ 356
Query: 260 ELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQ 318
E++ L K + +++ + L QL ++ IKE+LRL+PPVP R + L +G
Sbjct: 357 EVQE---LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRV 413
Query: 319 IPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEF 378
IPKG + S+ TH ++ + E ++P RF + ++ S +FIPF G R+C+G+ F
Sbjct: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAF 473
Query: 379 AKILLKI 385
A +K+
Sbjct: 474 AMAEMKV 480
>gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11
[Homo sapiens]
Length = 524
Score = 99.8 bits (247), Expect = 4e-21
Identities = 85/353 (24%), Positives = 159/353 (45%), Gaps = 22/353 (6%)
Query: 51 LGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERG---LL 107
LG G L + D + R+ ++ AF L+ Y+ + + V ++W G L
Sbjct: 132 LGDGLLLSGGDKWSRHRR-MLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLD 190
Query: 108 VYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLV---EAFEEMTRNLFSLPIDVPFSGL 164
++ + + + + E + AF E L D +
Sbjct: 191 MFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLT 250
Query: 165 YRGMKAR---NLIHARIEQNIRAKICGLRA--------SEAGQGCKDALQLLIEHSWERG 213
G + R +L+H + I+ + C L ++A D + +L+ E G
Sbjct: 251 PDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDG 310
Query: 214 ERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQD 273
+ L + ++ + +F GH+TTAS + ++ +L +P ++ R+E++ L K +
Sbjct: 311 KELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE---LLKDREP 367
Query: 274 NKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQIPKGWNVIYSICDT 332
+++ + L QL ++ IKE+LRL+PPVP R + F L +G IPKG + +I
Sbjct: 368 IEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGI 427
Query: 333 HDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKI 385
H ++ + E ++P RF + ++ S +FIPF G R+C+G+ FA +K+
Sbjct: 428 HYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
>gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11
[Homo sapiens]
Length = 524
Score = 99.8 bits (247), Expect = 4e-21
Identities = 85/353 (24%), Positives = 159/353 (45%), Gaps = 22/353 (6%)
Query: 51 LGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERG---LL 107
LG G L + D + R+ ++ AF L+ Y+ + + V ++W G L
Sbjct: 132 LGDGLLLSGGDKWSRHRR-MLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLD 190
Query: 108 VYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLV---EAFEEMTRNLFSLPIDVPFSGL 164
++ + + + + E + AF E L D +
Sbjct: 191 MFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLT 250
Query: 165 YRGMKAR---NLIHARIEQNIRAKICGLRA--------SEAGQGCKDALQLLIEHSWERG 213
G + R +L+H + I+ + C L ++A D + +L+ E G
Sbjct: 251 PDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDG 310
Query: 214 ERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQD 273
+ L + ++ + +F GH+TTAS + ++ +L +P ++ R+E++ L K +
Sbjct: 311 KELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE---LLKDREP 367
Query: 274 NKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQIPKGWNVIYSICDT 332
+++ + L QL ++ IKE+LRL+PPVP R + F L +G IPKG + +I
Sbjct: 368 IEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGI 427
Query: 333 HDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKI 385
H ++ + E ++P RF + ++ S +FIPF G R+C+G+ FA +K+
Sbjct: 428 HYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
>gi|13435391 cytochrome P450, family 4, subfamily F, polypeptide 2
[Homo sapiens]
Length = 520
Score = 97.4 bits (241), Expect = 2e-20
Identities = 85/359 (23%), Positives = 161/359 (44%), Gaps = 34/359 (9%)
Query: 51 LGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERG----- 105
LG G L + D + R+ ++ AF L+ Y+ + E V +W G
Sbjct: 132 LGDGLLLSAGDKWSRHRR-MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLD 190
Query: 106 ------LLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDV 159
L+ +++ +F +A + + + E+ ++ L
Sbjct: 191 MFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILLHIDFLYYLT 250
Query: 160 PFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQ------------LLIE 207
P +R +A L+H + I+ + R + QG D LQ +L+
Sbjct: 251 PDGQRFR--RACRLVHDFTDAVIQER----RRTLPSQGVDDFLQAKAKSKTLDFIDVLLL 304
Query: 208 HSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLL 267
E G++L + ++ + +F GH+TTAS + ++ +L +P ++ R+E++ L
Sbjct: 305 SKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE---L 361
Query: 268 CKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQIPKGWNVI 326
K + +++ + L L ++ +KE+LRL+PPVP R + L +G IPKG +
Sbjct: 362 LKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICL 421
Query: 327 YSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKI 385
S+ TH ++ + E ++P RF + ++ S +FIPF G R+C+G+ FA +K+
Sbjct: 422 ISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV 480
>gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide 12
[Homo sapiens]
Length = 524
Score = 97.1 bits (240), Expect = 3e-20
Identities = 56/195 (28%), Positives = 101/195 (51%), Gaps = 4/195 (2%)
Query: 200 DALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVRE 259
D + +L+ E G+ L + ++ + +FGGH+TTAS + ++ L +P ++ R+
Sbjct: 297 DFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQ 356
Query: 260 ELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQ 318
E++ L K +++ + L QL ++ +KE+LRL+PP P R + L +G
Sbjct: 357 EVQE---LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRV 413
Query: 319 IPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEF 378
IPKG + I H ++ + E ++P RF + + S +FIPF G R+C+G+ F
Sbjct: 414 IPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAF 473
Query: 379 AKILLKIFTVELARH 393
A +K+ + H
Sbjct: 474 AMAEMKVVLALMLLH 488
>gi|158138530 cytochrome P450, family 4, subfamily F, polypeptide 22
[Homo sapiens]
Length = 531
Score = 95.5 bits (236), Expect = 8e-20
Identities = 57/187 (30%), Positives = 100/187 (53%), Gaps = 4/187 (2%)
Query: 200 DALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVRE 259
D + +L+ E G+ L + ++ + +F GH+TT+S + ++ L YP +K RE
Sbjct: 304 DFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCRE 363
Query: 260 ELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQ 318
E++ + K + +L+ + L QL + IKE+LR PPV R + +L +G
Sbjct: 364 EIQE---VMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRI 420
Query: 319 IPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEF 378
IPKG + SI TH ++ + + +NP RF +P+ S +++PF G R+C+G+ F
Sbjct: 421 IPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSF 480
Query: 379 AKILLKI 385
A L++
Sbjct: 481 AMAELRV 487
>gi|5729796 cytochrome P450, family 46 [Homo sapiens]
Length = 500
Score = 95.1 bits (235), Expect = 1e-19
Identities = 101/430 (23%), Positives = 195/430 (45%), Gaps = 36/430 (8%)
Query: 4 RKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGS-----GCLSN 58
+KYG + + ++F + +V V ++V++ L+ +++T+ G G +S
Sbjct: 69 KKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSE 128
Query: 59 L-HDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGE-------RGLLVYP 110
++ HKQR+ VI AFSR +L + E+ +E + + + +L Y
Sbjct: 129 CNYERWHKQRR-VIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYT 187
Query: 111 EVKRLM---FRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRG 167
+ L F + +LLG + L+ Q + E +T + +L +P G +
Sbjct: 188 AMDILAKAAFGMETSMLLGAQKPLS------QAVKLMLEGITASRNTLAKFLP--GKRKQ 239
Query: 168 MK-ARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSST 226
++ R I R + + R +G + +L + D + L +
Sbjct: 240 LREVRESI--RFLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFV 297
Query: 227 ELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKY 286
GHET+A+ + L P ++ +++ E+ LD E L +L+Y
Sbjct: 298 TFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEV-----IGSKRYLDFEDLGRLQY 352
Query: 287 IGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFN 346
+ V+KE+LRL PP G FR+ + ++G ++P +++S + F + FN
Sbjct: 353 LSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFN 412
Query: 347 PDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPP-TM 405
PDRF P+ RF++ PF G RSC+G++FA++ +K+ +L + +++L+ G +
Sbjct: 413 PDRFGPGAPK--PRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGL 470
Query: 406 KTSPTVYPVD 415
+ T+ P+D
Sbjct: 471 QEQATLKPLD 480
>gi|29837648 cytochrome P450, family 4, subfamily X, polypeptide 1
[Homo sapiens]
Length = 509
Score = 95.1 bits (235), Expect = 1e-19
Identities = 87/361 (24%), Positives = 155/361 (42%), Gaps = 23/361 (6%)
Query: 50 ILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQW---LSCGERGL 106
+LG G L+ L Q ++++ F L+ Y+ V+ V L++W S + +
Sbjct: 120 LLGKG-LAALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSV 178
Query: 107 LVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEE---MTRNLFSLPI--DVPF 161
VY + + I M+ E + + FE + L+SL D+ F
Sbjct: 179 EVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIF 238
Query: 162 SGL---YRGMKARNLIHARIEQNIRAKICGLRASEAGQGC-----KDALQLLIEHSWERG 213
YR K +++ + I+ + L+A +D L +++ E G
Sbjct: 239 KLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAKDESG 298
Query: 214 ERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQD 273
+ + L GH+T A++ + ++ L L P ++ REE++ G+L
Sbjct: 299 SSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVR--GIL---GDG 353
Query: 274 NKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQIPKGWNVIYSICDT 332
+ + + L ++ Y IKET RL P VP R K +G +P G V+ SI
Sbjct: 354 SSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGL 413
Query: 333 HDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELAR 392
H ++ N + F+P RF + + ++++PF G R+C+G+EFA I LK+ +
Sbjct: 414 HHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILL 473
Query: 393 H 393
H
Sbjct: 474 H 474
>gi|153218660 cytochrome P450, family 4, subfamily B, polypeptide 1
isoform b [Homo sapiens]
Length = 511
Score = 94.0 bits (232), Expect = 2e-19
Identities = 84/340 (24%), Positives = 148/340 (43%), Gaps = 26/340 (7%)
Query: 66 QRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLL--VYPEVKRLMFRIAMRI 123
Q +K++ F + L+ YV V TE L++W G ++ +V + M+
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 124 LLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLY---------RGMKARNLI 174
G G DS L A ++T + + + + R ++A +
Sbjct: 196 TFGRGDTGLGHRDSSYYL--AVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVA 253
Query: 175 HARIEQNIRAKICGLRASEAGQGCK-----DALQLLIEHSWERGERLDMQALKQSSTELL 229
H +Q IR + L+ + + + D L +L+ E +L L+ +
Sbjct: 254 HDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFM 313
Query: 230 FGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGC 289
F GH+TT S + + + LYP + REE++ +QD + L ++ Y+
Sbjct: 314 FEGHDTTTSGISWFLYCMALYPEHQHRCREEVRE----ILGDQDF-FQWDDLGKMTYLTM 368
Query: 290 VIKETLRLNPPVPGGFRVALK--TFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNP 347
IKE+ RL PPVP +R K TF ++G +P G + I H + ++ + E F+
Sbjct: 369 CIKESFRLYPPVPQVYRQLSKPVTF-VDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDS 427
Query: 348 DRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFT 387
RF + F+F+PF G R+C+G++FA +K+ T
Sbjct: 428 LRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 467
>gi|16933533 cytochrome P450, family 3, subfamily A, polypeptide 43
isoform 2 [Homo sapiens]
Length = 503
Score = 93.6 bits (231), Expect = 3e-19
Identities = 61/204 (29%), Positives = 104/204 (50%), Gaps = 16/204 (7%)
Query: 217 DMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKL 276
D++ + QS ++F ++TT++ ++ L +P V QK++EE+ + NK
Sbjct: 292 DLELVAQSII-IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAV-------LPNKA 343
Query: 277 DM--EILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHD 334
+ + L Q++Y+ V+ ETLRL P V RV K E+NG IPKG V+ I H
Sbjct: 344 PVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHH 403
Query: 335 VAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHC 394
+ +T E+F P+RF + + + +IPFG G R+C+G FA +K+ + ++
Sbjct: 404 DPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNF 463
Query: 395 DWQLLNGPPTMKTSPTVYPVDNLP 418
++ K + +DNLP
Sbjct: 464 SFK------PCKETQIPLKLDNLP 481
>gi|4503233 cytochrome P450, family 3, subfamily A, polypeptide 7
[Homo sapiens]
Length = 503
Score = 92.4 bits (228), Expect = 7e-19
Identities = 64/209 (30%), Positives = 106/209 (50%), Gaps = 11/209 (5%)
Query: 190 RASEAGQGCKDALQLLIEHSWERGERL-----DMQALKQSSTELLFGGHETTASAATSLI 244
R E + D LQL+I+ + D++ + QS +F G+ETT+S + +I
Sbjct: 260 RLKETQKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSII-FIFAGYETTSSVLSFII 318
Query: 245 TYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGG 304
L +P V QKV++E+ + + + D + QL+Y+ V+ ETLRL P
Sbjct: 319 YELATHPDVQQKVQKEIDT---VLPNKAPPTYDTVL--QLEYLDMVVNETLRLFPVAMRL 373
Query: 305 FRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFI 364
RV K E+NG IPKG V+ H + +T E+F P+RF + ++ + +
Sbjct: 374 ERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYT 433
Query: 365 PFGGGLRSCVGKEFAKILLKIFTVELARH 393
PFG G R+C+G FA + +K+ V + ++
Sbjct: 434 PFGSGPRNCIGMRFALVNMKLALVRVLQN 462
>gi|6005737 cytochrome P450, family 4, subfamily F, polypeptide 8
[Homo sapiens]
Length = 520
Score = 92.0 bits (227), Expect = 9e-19
Identities = 53/187 (28%), Positives = 101/187 (54%), Gaps = 4/187 (2%)
Query: 200 DALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVRE 259
D + +L+ + G+ L + ++ + +FGGH+TTAS + ++ L +P ++ R+
Sbjct: 297 DFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQ 356
Query: 260 ELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQ 318
E++ L K + +++ + L QL ++ +KE+LRL+PP+P R + L +
Sbjct: 357 EVQE---LLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRV 413
Query: 319 IPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEF 378
IPKG +I H ++ + E ++P RF + + S +FIPF G R+C+G++F
Sbjct: 414 IPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKF 473
Query: 379 AKILLKI 385
A +K+
Sbjct: 474 AMAEMKV 480
>gi|153218662 cytochrome P450, family 4, subfamily B, polypeptide 1
isoform a [Homo sapiens]
Length = 512
Score = 91.3 bits (225), Expect = 2e-18
Identities = 84/341 (24%), Positives = 149/341 (43%), Gaps = 27/341 (7%)
Query: 66 QRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLL--VYPEVKRLMFRIAMRI 123
Q +K++ F + L+ YV V TE L++W G ++ +V + M+
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 124 LLGC-EPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLY---------RGMKARNL 173
G + L DS L A ++T + + + + R ++A +
Sbjct: 196 TFGRGDTGLGHSRDSSYYL--AVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQV 253
Query: 174 IHARIEQNIRAKICGLRASEAGQGCK-----DALQLLIEHSWERGERLDMQALKQSSTEL 228
H +Q IR + L+ + + + D L +L+ E +L L+
Sbjct: 254 AHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTF 313
Query: 229 LFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIG 288
+F GH+TT S + + + LYP + REE++ +QD + L ++ Y+
Sbjct: 314 MFEGHDTTTSGISWFLYCMALYPEHQHRCREEVRE----ILGDQDF-FQWDDLGKMTYLT 368
Query: 289 CVIKETLRLNPPVPGGFRVALK--TFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFN 346
IKE+ RL PPVP +R K TF ++G +P G + I H + ++ + E F+
Sbjct: 369 MCIKESFRLYPPVPQVYRQLSKPVTF-VDGRSLPAGSLISMHIYALHRNSAVWPDPEVFD 427
Query: 347 PDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFT 387
RF + F+F+PF G R+C+G++FA +K+ T
Sbjct: 428 SLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 468
>gi|30023836 cytochrome P450 4Z1 [Homo sapiens]
Length = 505
Score = 90.5 bits (223), Expect = 3e-18
Identities = 85/345 (24%), Positives = 144/345 (41%), Gaps = 20/345 (5%)
Query: 56 LSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLS--CGERGLLVYPEVK 113
L L S K+ ++++ F+ L+ ++ +++E V L +W L ++ V
Sbjct: 125 LVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVS 184
Query: 114 RLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFE-----EMTRNLFSLPIDVPFSGLYRGM 168
+ M+ + + D + L F N F D+ F +G
Sbjct: 185 LMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQ 244
Query: 169 ---KARNLIHARIEQNIRAKICGLRASEAGQGCK----DALQLLIEHSWERGERLDMQAL 221
K +H E+ I+ + L+ + D L +L+ E + L
Sbjct: 245 IFSKFNQELHQFTEKVIQDRKESLKDKLKQDTTQKRRWDFLDILLSAKSENTKDFSEADL 304
Query: 222 KQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEIL 281
+ +F GH+TT+SA + ++ L YP Q+ R+E++ LL + + E L
Sbjct: 305 QAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRE--LL---GDGSSITWEHL 359
Query: 282 EQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQIPKGWNVIYSICDTHDVAEIFT 340
Q+ Y IKE LRL PV R+ K +G +P G V +I H +
Sbjct: 360 SQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWE 419
Query: 341 NKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKI 385
+ + FNP RF + E ++FIPF GLR+C+G+ FA I K+
Sbjct: 420 DPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKV 464
>gi|13435386 cytochrome P450, family 3, subfamily A, polypeptide 4
[Homo sapiens]
Length = 503
Score = 90.1 bits (222), Expect = 3e-18
Identities = 97/407 (23%), Positives = 177/407 (43%), Gaps = 27/407 (6%)
Query: 4 RKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSS 63
+KYG ++ + +P + + D ++ +L+ E V + +S D
Sbjct: 66 KKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEE 125
Query: 64 HKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRI 123
K+ + ++ F+ L+ VP+I + + E G V +K + +M +
Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPV--TLKDVFGAYSMDV 183
Query: 124 LLGCEPQLAGDGDSEQQLVEAFEEMTRNL--------FSLPIDVPFSGLYRGMKARNL-- 173
+ + D + Q + F E T+ L F L I V F L ++ N+
Sbjct: 184 ITSTSFGVNIDSLNNPQ--DPFVENTKKLLRFDFLDPFFLSITV-FPFLIPILEVLNICV 240
Query: 174 IHARIEQNIRAKICGLRASEAGQGCK---DALQLLIEHS----WERGERLDMQALKQSST 226
+ +R + ++ S K D LQL+I+ E + L L S
Sbjct: 241 FPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSI 300
Query: 227 ELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKY 286
+F G+ETT+S + ++ L +P V QK++EE+ + + + D + Q++Y
Sbjct: 301 IFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDA---VLPNKAPPTYDTVL--QMEY 355
Query: 287 IGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFN 346
+ V+ ETLRL P RV K E+NG IPKG V+ H + +T E+F
Sbjct: 356 LDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFL 415
Query: 347 PDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 393
P+RF + ++ + + PFG G R+C+G FA + +K+ + + ++
Sbjct: 416 PERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQN 462
>gi|12383060 cytochrome P450, family 3, subfamily A, polypeptide 43
isoform 1 [Homo sapiens]
Length = 504
Score = 89.0 bits (219), Expect = 8e-18
Identities = 61/205 (29%), Positives = 104/205 (50%), Gaps = 17/205 (8%)
Query: 217 DMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKL 276
D++ + QS ++F ++TT++ ++ L +P V QK++EE+ + NK
Sbjct: 292 DLELVAQSII-IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAV-------LPNKA 343
Query: 277 DM--EILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHD 334
+ + L Q++Y+ V+ ETLRL P V RV K E+NG IPKG V+ I H
Sbjct: 344 PVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHH 403
Query: 335 VAEIFTNKEEFNPD-RFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 393
+ +T E+F P+ RF + + + +IPFG G R+C+G FA +K+ + ++
Sbjct: 404 DPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQN 463
Query: 394 CDWQLLNGPPTMKTSPTVYPVDNLP 418
++ K + +DNLP
Sbjct: 464 FSFK------PCKETQIPLKLDNLP 482
>gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5
[Homo sapiens]
Length = 502
Score = 87.4 bits (215), Expect = 2e-17
Identities = 95/408 (23%), Positives = 173/408 (42%), Gaps = 30/408 (7%)
Query: 4 RKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSS 63
+KYG ++ T+ P + + D +R +L+ E V + + +S D
Sbjct: 66 KKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEE 125
Query: 64 HKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRI 123
K+ + ++ F+ L+ P+I + + E+G V +K + +M +
Sbjct: 126 WKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPV--TLKDIFGAYSMDV 183
Query: 124 LLGCEPQLAGDGDSEQQLVEAFEEMTR-------------NLFSLPIDVP-FSGLYRGMK 169
+ G + D + Q + F E T+ ++ P P F L +
Sbjct: 184 ITGTSFGVNIDSLNNPQ--DPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLF 241
Query: 170 ARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHS----WERGERLDMQALKQSS 225
++ I+ + R K L + + D LQL+I+ E + L L S
Sbjct: 242 PKDTINFLSKSVNRMKKSRLNDKQKHR--LDFLQLMIDSQNSKETESHKALSDLELAAQS 299
Query: 226 TELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLK 285
+F G+ETT+S + + L +P V QK+++E+ + + + D + Q++
Sbjct: 300 IIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDA---VLPNKAPPTYDAVV--QME 354
Query: 286 YIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEF 345
Y+ V+ ETLRL P R K E+NG IPKG V+ H + +T EEF
Sbjct: 355 YLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEF 414
Query: 346 NPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 393
P+RF + + + PFG G R+C+G FA + +K+ + + ++
Sbjct: 415 RPERFS-KKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQN 461
>gi|55770850 cytochrome P450 family 24 subfamily A polypeptide 1
isoform 1 precursor [Homo sapiens]
Length = 514
Score = 85.5 bits (210), Expect = 8e-17
Identities = 64/208 (30%), Positives = 100/208 (48%), Gaps = 7/208 (3%)
Query: 215 RLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDN 274
RL + L + TEL ETTA++ ++ L P V QK+ +E++S + NQ
Sbjct: 310 RLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQS---VLPENQVP 366
Query: 275 KLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHD 334
+ E L + Y+ +KE++RL P VP R K L Y +PKG ++ +
Sbjct: 367 RA--EDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGS 424
Query: 335 VAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHC 394
+ F + +F P+R+ L E + F+ +PFG G R C+G+ A++ L + + R
Sbjct: 425 SEDNFEDSSQFRPERW-LQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKY 483
Query: 395 DWQLL-NGPPTMKTSPTVYPVDNLPARF 421
D Q N P M S T+ P LP F
Sbjct: 484 DIQATDNEPVEMLHSGTLVPSRELPIAF 511
>gi|167466231 cytochrome P450, family 27, subfamily C, polypeptide 1
[Homo sapiens]
Length = 372
Score = 85.5 bits (210), Expect = 8e-17
Identities = 56/182 (30%), Positives = 94/182 (51%), Gaps = 8/182 (4%)
Query: 214 ERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKV-REELKSKGLLCKSNQ 272
+ L +Q + + TE+L G +TT+ + + L +P V Q V RE +K+ G + +
Sbjct: 163 QALTLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLG---ERHV 219
Query: 273 DNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDT 332
D+ ++ + ++KETLRL P +PG RV + + GY IPKG + T
Sbjct: 220 PTAADVP---KVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYAT 276
Query: 333 HDVAEIFTNKEEFNPDRFMLPHPED-ASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELA 391
E F +EF P+R++ D F IPFG G+RSC+G+ A++ + + ++L
Sbjct: 277 SYQDENFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLL 336
Query: 392 RH 393
+H
Sbjct: 337 QH 338
>gi|13449277 cytochrome P450, family 2, subfamily S, polypeptide 1
[Homo sapiens]
Length = 504
Score = 82.4 bits (202), Expect = 7e-16
Identities = 62/195 (31%), Positives = 88/195 (45%), Gaps = 6/195 (3%)
Query: 228 LLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYI 287
LLF G T ++ + L YPHV + VREEL + + Q L +L Y
Sbjct: 299 LLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRE---LGAGQAPSLGDRT--RLPYT 353
Query: 288 GCVIKETLRLNPPVPGGF-RVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFN 346
V+ E RL VP G R ++T GY +P+G V + IF + EEFN
Sbjct: 354 DAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFN 413
Query: 347 PDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMK 406
PDRF+ +F+PF G R C+G+ AK L +F + + + P T+
Sbjct: 414 PDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAFSLESPCPPDTLS 473
Query: 407 TSPTVYPVDNLPARF 421
PTV + N+P F
Sbjct: 474 LKPTVSGLFNIPPAF 488
>gi|4503213 cytochrome P450, family 27, subfamily B, polypeptide 1
[Homo sapiens]
Length = 508
Score = 80.9 bits (198), Expect = 2e-15
Identities = 63/217 (29%), Positives = 101/217 (46%), Gaps = 20/217 (9%)
Query: 214 ERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQD 273
E L Q++ + TELL G +T ++ + + L +P V + E+ +
Sbjct: 300 EELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAA---LSPGSS 356
Query: 274 NKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSIC--- 330
+L QL + V+KE LRL P VPG RV K + Y IPK N + ++C
Sbjct: 357 AYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPK--NTLVTLCHYA 414
Query: 331 DTHDVAEIFTNKEEFNPDRFM----LPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIF 386
+ D A+ F F P R++ PHP F+ +PFG G RSC+G+ A++ L++
Sbjct: 415 TSRDPAQ-FPEPNSFRPARWLGEGPTPHP-----FASLPFGFGKRSCMGRRLAELELQMA 468
Query: 387 TVELARHCDWQLLNG--PPTMKTSPTVYPVDNLPARF 421
++ H + Q G P KT + P ++ +F
Sbjct: 469 LAQILTHFEVQPEPGAAPVRPKTRTVLVPERSINLQF 505
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,558,391
Number of Sequences: 37866
Number of extensions: 723328
Number of successful extensions: 1696
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1513
Number of HSP's gapped (non-prelim): 90
length of query: 428
length of database: 18,247,518
effective HSP length: 105
effective length of query: 323
effective length of database: 14,271,588
effective search space: 4609722924
effective search space used: 4609722924
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.