Search of human proteins with 112382377

Search of human proteins with 112382377

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|112382377 ubiquitin-conjugating enzyme E2S [Homo sapiens]
         (222 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|112382377 ubiquitin-conjugating enzyme E2S [Homo sapiens]          452   e-127
gi|4507771 ubiquitin-conjugating enzyme E2B [Homo sapiens]            110   7e-25
gi|4507775 ubiquitin-conjugating enzyme E2D 2 isoform 1 [Homo sa...   110   1e-24
gi|4507793 ubiquitin-conjugating enzyme E2N [Homo sapiens]            110   1e-24
gi|8393719 ubiquitin-conjugating enzyme E2D 4 (putative) [Homo s...   109   2e-24
gi|33149322 ubiquitin-conjugating enzyme E2D 3 isoform 2 [Homo s...   109   2e-24
gi|32967280 ubiquitin-conjugating enzyme E2A isoform 1 [Homo sap...   108   4e-24
gi|33149320 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...   107   1e-23
gi|33149318 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...   107   1e-23
gi|33149316 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...   107   1e-23
gi|33149314 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...   107   1e-23
gi|33149312 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...   107   1e-23
gi|33149310 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...   107   1e-23
gi|4507777 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo sa...   107   1e-23
gi|33149324 ubiquitin-conjugating enzyme E2D 3 isoform 3 [Homo s...   105   2e-23
gi|4507773 ubiquitin-conjugating enzyme E2D 1 [Homo sapiens]          105   3e-23
gi|4885417 ubiquitin-conjugating enzyme E2K isoform 1 [Homo sapi...    97   8e-21
gi|33188456 ubiquitin-conjugating enzyme E2D 2 isoform 2 [Homo s...    96   3e-20
gi|7661808 ubiquitin-conjugating enzyme E2T [Homo sapiens]             94   1e-19
gi|33359694 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]          94   1e-19
gi|5454146 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]           94   1e-19
gi|61175265 ubiquitin-conjugating enzyme E2N-like [Homo sapiens]       94   1e-19
gi|22749327 ubiquitin-conjugating enzyme E2E 2 [Homo sapiens]          93   2e-19
gi|4507779 ubiquitin-conjugating enzyme E2E 1 isoform 1 [Homo sa...    91   8e-19
gi|35494003 ubiquitin-conjugating enzyme E2I [Homo sapiens]            90   2e-18
gi|35493996 ubiquitin-conjugating enzyme E2I [Homo sapiens]            90   2e-18
gi|35493987 ubiquitin-conjugating enzyme E2I [Homo sapiens]            90   2e-18
gi|4507785 ubiquitin-conjugating enzyme E2I [Homo sapiens]             90   2e-18
gi|163660385 ubiquitin-conjugating enzyme E2K isoform 2 [Homo sa...    88   5e-18
gi|29893557 ubiquitin-conjugating enzyme E2G 2 isoform 1 [Homo s...    84   1e-16

>gi|112382377 ubiquitin-conjugating enzyme E2S [Homo sapiens]
          Length = 222

 Score =  452 bits (1162), Expect = e-127
 Identities = 222/222 (100%), Positives = 222/222 (100%)

Query: 1   MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF 60
           MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF
Sbjct: 1   MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF 60

Query: 61  RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL 120
           RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL
Sbjct: 61  RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL 120

Query: 121 IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST 180
           IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST
Sbjct: 121 IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST 180

Query: 181 DPGAPGGPGGAEGPMAKKHAGERDKKLAAKKKTDKKRALRRL 222
           DPGAPGGPGGAEGPMAKKHAGERDKKLAAKKKTDKKRALRRL
Sbjct: 181 DPGAPGGPGGAEGPMAKKHAGERDKKLAAKKKTDKKRALRRL 222


>gi|4507771 ubiquitin-conjugating enzyme E2B [Homo sapiens]
          Length = 152

 Score =  110 bits (276), Expect = 7e-25
 Identities = 51/140 (36%), Positives = 80/140 (57%)

Query: 14  RLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPAS 73
           R + ++   L  DPP G+   P+E ++      I GPEGTP+  G F++ +   +++P  
Sbjct: 7   RRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNK 66

Query: 74  PPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEA 133
           PP   FL+K+FHPNV A+G IC+++L+  W+    +  +L +I+ LL  PNP S  N +A
Sbjct: 67  PPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQA 126

Query: 134 GRLLLENYEEYAARARLLTE 153
            +L  EN  EY  R   + E
Sbjct: 127 AQLYQENKREYEKRVSAIVE 146


>gi|4507775 ubiquitin-conjugating enzyme E2D 2 isoform 1 [Homo
           sapiens]
          Length = 147

 Score =  110 bits (275), Expect = 1e-24
 Identities = 54/141 (38%), Positives = 81/141 (57%)

Query: 13  IRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPA 72
           ++ ++KE+  L  DPP      P  +D+   Q TI GP  +PY GG+F + +    D+P 
Sbjct: 3   LKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPF 62

Query: 73  SPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEE 132
            PPK  F T+I+HPN+ +NG IC+++L+  W+  L I  VLL+I  LL  PNP+  L  E
Sbjct: 63  KPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPE 122

Query: 133 AGRLLLENYEEYAARARLLTE 153
             R+   + E+Y   AR  T+
Sbjct: 123 IARIYKTDREKYNRIAREWTQ 143


>gi|4507793 ubiquitin-conjugating enzyme E2N [Homo sapiens]
          Length = 152

 Score =  110 bits (274), Expect = 1e-24
 Identities = 55/142 (38%), Positives = 82/142 (57%)

Query: 14  RLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPAS 73
           R + KE   L A+P  GIK  P+E +     V I GP+ +P+ GG F+++L L +++P +
Sbjct: 6   RRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMA 65

Query: 74  PPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEA 133
            PK  F+TKI+HPNV   G IC+++LK  W+  L IR VLL+I+ LL  PNP+  L  + 
Sbjct: 66  APKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDV 125

Query: 134 GRLLLENYEEYAARARLLTEIH 155
                 N  +    AR  T ++
Sbjct: 126 AEQWKTNEAQAIETARAWTRLY 147


>gi|8393719 ubiquitin-conjugating enzyme E2D 4 (putative) [Homo
           sapiens]
          Length = 147

 Score =  109 bits (273), Expect = 2e-24
 Identities = 55/141 (39%), Positives = 79/141 (56%)

Query: 13  IRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPA 72
           ++ + KE+T L  DPP      P  +DL   Q TI GP  +PY GG+F + +    D+P 
Sbjct: 3   LKRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPF 62

Query: 73  SPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEE 132
            PPK  F TKI+HPN+ +NG IC+++L+  W+  L +  VLL+I  LL  PNP+  L  E
Sbjct: 63  KPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPE 122

Query: 133 AGRLLLENYEEYAARARLLTE 153
                  + E+Y   AR  T+
Sbjct: 123 IAHTYKADREKYNRLAREWTQ 143


>gi|33149322 ubiquitin-conjugating enzyme E2D 3 isoform 2 [Homo
           sapiens]
          Length = 148

 Score =  109 bits (273), Expect = 2e-24
 Identities = 54/141 (38%), Positives = 81/141 (57%)

Query: 13  IRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPA 72
           ++ + KE++ L  DPP      P  +D+   Q TI GP  +PY GG+F + +    D+P 
Sbjct: 3   LKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPF 62

Query: 73  SPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEE 132
            PPK  F T+I+HPN+ +NG IC+++L+  W+  L I  VLL+I  LL  PNP+  L  E
Sbjct: 63  KPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPE 122

Query: 133 AGRLLLENYEEYAARARLLTE 153
             R+   + ++Y   AR  TE
Sbjct: 123 IARIYKTDRDKYNRLAREWTE 143


>gi|32967280 ubiquitin-conjugating enzyme E2A isoform 1 [Homo
           sapiens]
          Length = 152

 Score =  108 bits (270), Expect = 4e-24
 Identities = 50/140 (35%), Positives = 80/140 (57%)

Query: 14  RLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPAS 73
           R + ++   L  DPP G+   P+E ++      I GPEGTP+  G F++ +   +++P  
Sbjct: 7   RRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNK 66

Query: 74  PPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEA 133
           PP   F++K+FHPNV A+G IC+++L+  W+    +  +L +I+ LL  PNP S  N +A
Sbjct: 67  PPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQA 126

Query: 134 GRLLLENYEEYAARARLLTE 153
            +L  EN  EY  R   + E
Sbjct: 127 AQLYQENKREYEKRVSAIVE 146


>gi|33149320 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score =  107 bits (266), Expect = 1e-23
 Identities = 52/141 (36%), Positives = 81/141 (57%)

Query: 13  IRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPA 72
           ++ + KE++ L  DPP      P  +D+   Q TI GP  +PY GG+F + +    D+P 
Sbjct: 3   LKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPF 62

Query: 73  SPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEE 132
            PPK  F T+I+HPN+ +NG IC+++L+  W+  L I  VLL+I  LL  PNP+  L  E
Sbjct: 63  KPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPE 122

Query: 133 AGRLLLENYEEYAARARLLTE 153
             R+   + ++Y   +R  T+
Sbjct: 123 IARIYKTDRDKYNRISREWTQ 143


>gi|33149318 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score =  107 bits (266), Expect = 1e-23
 Identities = 52/141 (36%), Positives = 81/141 (57%)

Query: 13  IRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPA 72
           ++ + KE++ L  DPP      P  +D+   Q TI GP  +PY GG+F + +    D+P 
Sbjct: 3   LKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPF 62

Query: 73  SPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEE 132
            PPK  F T+I+HPN+ +NG IC+++L+  W+  L I  VLL+I  LL  PNP+  L  E
Sbjct: 63  KPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPE 122

Query: 133 AGRLLLENYEEYAARARLLTE 153
             R+   + ++Y   +R  T+
Sbjct: 123 IARIYKTDRDKYNRISREWTQ 143


>gi|33149316 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score =  107 bits (266), Expect = 1e-23
 Identities = 52/141 (36%), Positives = 81/141 (57%)

Query: 13  IRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPA 72
           ++ + KE++ L  DPP      P  +D+   Q TI GP  +PY GG+F + +    D+P 
Sbjct: 3   LKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPF 62

Query: 73  SPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEE 132
            PPK  F T+I+HPN+ +NG IC+++L+  W+  L I  VLL+I  LL  PNP+  L  E
Sbjct: 63  KPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPE 122

Query: 133 AGRLLLENYEEYAARARLLTE 153
             R+   + ++Y   +R  T+
Sbjct: 123 IARIYKTDRDKYNRISREWTQ 143


>gi|33149314 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score =  107 bits (266), Expect = 1e-23
 Identities = 52/141 (36%), Positives = 81/141 (57%)

Query: 13  IRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPA 72
           ++ + KE++ L  DPP      P  +D+   Q TI GP  +PY GG+F + +    D+P 
Sbjct: 3   LKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPF 62

Query: 73  SPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEE 132
            PPK  F T+I+HPN+ +NG IC+++L+  W+  L I  VLL+I  LL  PNP+  L  E
Sbjct: 63  KPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPE 122

Query: 133 AGRLLLENYEEYAARARLLTE 153
             R+   + ++Y   +R  T+
Sbjct: 123 IARIYKTDRDKYNRISREWTQ 143


>gi|33149312 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score =  107 bits (266), Expect = 1e-23
 Identities = 52/141 (36%), Positives = 81/141 (57%)

Query: 13  IRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPA 72
           ++ + KE++ L  DPP      P  +D+   Q TI GP  +PY GG+F + +    D+P 
Sbjct: 3   LKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPF 62

Query: 73  SPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEE 132
            PPK  F T+I+HPN+ +NG IC+++L+  W+  L I  VLL+I  LL  PNP+  L  E
Sbjct: 63  KPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPE 122

Query: 133 AGRLLLENYEEYAARARLLTE 153
             R+   + ++Y   +R  T+
Sbjct: 123 IARIYKTDRDKYNRISREWTQ 143


>gi|33149310 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score =  107 bits (266), Expect = 1e-23
 Identities = 52/141 (36%), Positives = 81/141 (57%)

Query: 13  IRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPA 72
           ++ + KE++ L  DPP      P  +D+   Q TI GP  +PY GG+F + +    D+P 
Sbjct: 3   LKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPF 62

Query: 73  SPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEE 132
            PPK  F T+I+HPN+ +NG IC+++L+  W+  L I  VLL+I  LL  PNP+  L  E
Sbjct: 63  KPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPE 122

Query: 133 AGRLLLENYEEYAARARLLTE 153
             R+   + ++Y   +R  T+
Sbjct: 123 IARIYKTDRDKYNRISREWTQ 143


>gi|4507777 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score =  107 bits (266), Expect = 1e-23
 Identities = 52/141 (36%), Positives = 81/141 (57%)

Query: 13  IRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPA 72
           ++ + KE++ L  DPP      P  +D+   Q TI GP  +PY GG+F + +    D+P 
Sbjct: 3   LKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPF 62

Query: 73  SPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEE 132
            PPK  F T+I+HPN+ +NG IC+++L+  W+  L I  VLL+I  LL  PNP+  L  E
Sbjct: 63  KPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPE 122

Query: 133 AGRLLLENYEEYAARARLLTE 153
             R+   + ++Y   +R  T+
Sbjct: 123 IARIYKTDRDKYNRISREWTQ 143


>gi|33149324 ubiquitin-conjugating enzyme E2D 3 isoform 3 [Homo
           sapiens]
          Length = 149

 Score =  105 bits (263), Expect = 2e-23
 Identities = 52/136 (38%), Positives = 78/136 (57%)

Query: 18  KEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKG 77
           KE++ L  DPP      P  +D+   Q TI GP  +PY GG+F + +    D+P  PPK 
Sbjct: 10  KELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKV 69

Query: 78  YFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGRLL 137
            F T+I+HPN+ +NG IC+++L+  W+  L I  VLL+I  LL  PNP+  L  E  R+ 
Sbjct: 70  AFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIY 129

Query: 138 LENYEEYAARARLLTE 153
             + ++Y   +R  T+
Sbjct: 130 KTDRDKYNRISREWTQ 145


>gi|4507773 ubiquitin-conjugating enzyme E2D 1 [Homo sapiens]
          Length = 147

 Score =  105 bits (262), Expect = 3e-23
 Identities = 52/141 (36%), Positives = 80/141 (56%)

Query: 13  IRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPA 72
           ++ + KE++ L  DPP      P  +DL   Q TI GP  + Y GG+F + +    D+P 
Sbjct: 3   LKRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPF 62

Query: 73  SPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEE 132
            PPK  F TKI+HPN+ +NG IC+++L+  W+  L +  VLL+I  LL  PNP+  L  +
Sbjct: 63  KPPKIAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPD 122

Query: 133 AGRLLLENYEEYAARARLLTE 153
             ++   + E+Y   AR  T+
Sbjct: 123 IAQIYKSDKEKYNRHAREWTQ 143


>gi|4885417 ubiquitin-conjugating enzyme E2K isoform 1 [Homo
           sapiens]
          Length = 200

 Score = 97.4 bits (241), Expect = 8e-21
 Identities = 51/153 (33%), Positives = 86/153 (56%), Gaps = 1/153 (0%)

Query: 7   NLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLL 66
           N+    I+  +KEV        + IKV   +E+ T+L+  I GP  TPY GG +++++ +
Sbjct: 3   NIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKI 62

Query: 67  GKDFPASPPKGYFLTKIFHPNVGA-NGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNP 125
            + +P +PPK  F+TKI+HPN+ +  G IC+++LK  W A + +R VLL+++ LL    P
Sbjct: 63  PETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEP 122

Query: 126 ESALNEEAGRLLLENYEEYAARARLLTEIHGGA 158
           +   +        +N E +   ARL   ++ GA
Sbjct: 123 DDPQDAVVANQYKQNPEMFKQTARLWAHVYAGA 155


>gi|33188456 ubiquitin-conjugating enzyme E2D 2 isoform 2 [Homo
           sapiens]
          Length = 118

 Score = 95.5 bits (236), Expect = 3e-20
 Identities = 46/110 (41%), Positives = 66/110 (60%)

Query: 44  QVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDW 103
           Q TI GP  +PY GG+F + +    D+P  PPK  F T+I+HPN+ +NG IC+++L+  W
Sbjct: 5   QATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQW 64

Query: 104 TAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLLENYEEYAARARLLTE 153
           +  L I  VLL+I  LL  PNP+  L  E  R+   + E+Y   AR  T+
Sbjct: 65  SPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWTQ 114


>gi|7661808 ubiquitin-conjugating enzyme E2T [Homo sapiens]
          Length = 197

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 48/142 (33%), Positives = 78/142 (54%), Gaps = 4/142 (2%)

Query: 18  KEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKG 77
           +E+  L  +PP GI  + +++ + DL+  I G   TPY  G+F++++++ + +P  PP+ 
Sbjct: 9   RELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPERYPFEPPQI 68

Query: 78  YFLTKIFHPNVGANGEICVNVLKRD----WTAELGIRHVLLTIKCLLIHPNPESALNEEA 133
            FLT I+HPN+ + G IC++VLK      W   L I  VL +I+ L+  PNP+  L  + 
Sbjct: 69  RFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNPDDPLMADI 128

Query: 134 GRLLLENYEEYAARARLLTEIH 155
                 N   +   AR  TE H
Sbjct: 129 SSEFKYNKPAFLKNARQWTEKH 150


>gi|33359694 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]
          Length = 207

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 49/138 (35%), Positives = 74/138 (53%)

Query: 16  VYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPP 75
           + KE+  +T DPP      P  +++ + + TI GP G+ Y GG+F + +    D+P  PP
Sbjct: 66  IQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPP 125

Query: 76  KGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGR 135
           K  F T+I+H N+ + G IC+++LK +W+  L I  VLL+I  LL   NP   L      
Sbjct: 126 KVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIAT 185

Query: 136 LLLENYEEYAARARLLTE 153
             L N  E+   AR  T+
Sbjct: 186 QYLTNRAEHDRIARQWTK 203


>gi|5454146 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]
          Length = 207

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 49/138 (35%), Positives = 74/138 (53%)

Query: 16  VYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPP 75
           + KE+  +T DPP      P  +++ + + TI GP G+ Y GG+F + +    D+P  PP
Sbjct: 66  IQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPP 125

Query: 76  KGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGR 135
           K  F T+I+H N+ + G IC+++LK +W+  L I  VLL+I  LL   NP   L      
Sbjct: 126 KVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIAT 185

Query: 136 LLLENYEEYAARARLLTE 153
             L N  E+   AR  T+
Sbjct: 186 QYLTNRAEHDRIARQWTK 203


>gi|61175265 ubiquitin-conjugating enzyme E2N-like [Homo sapiens]
          Length = 153

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 52/141 (36%), Positives = 78/141 (55%), Gaps = 1/141 (0%)

Query: 16  VYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGP-EGTPYAGGLFRMKLLLGKDFPASP 74
           + KE   L A+P  GIK  P+E +     V I G  + +P+ GG F+ +LLL +++P + 
Sbjct: 8   IIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGESKDSPFEGGTFKRELLLAEEYPMAA 67

Query: 75  PKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEAG 134
           PK  F+TKI+HPNV     I +++LK  W+  L IR VLL+I+ LL  PNP+  L  +  
Sbjct: 68  PKVRFMTKIYHPNVDKLERISLDILKDKWSPALQIRTVLLSIQALLNAPNPDDPLANDVV 127

Query: 135 RLLLENYEEYAARARLLTEIH 155
                N  +    AR  T ++
Sbjct: 128 EQWKTNEAQAIETARAWTRLY 148


>gi|22749327 ubiquitin-conjugating enzyme E2E 2 [Homo sapiens]
          Length = 201

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 48/138 (34%), Positives = 74/138 (53%)

Query: 16  VYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPP 75
           + KE+  +T DPP      P  +++ + + TI GP G+ Y GG+F + +    D+P  PP
Sbjct: 60  IQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSPDYPFKPP 119

Query: 76  KGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGR 135
           K  F T+I+H N+ + G IC+++LK +W+  L I  VLL+I  LL   NP   L      
Sbjct: 120 KVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIAT 179

Query: 136 LLLENYEEYAARARLLTE 153
             + N  E+   AR  T+
Sbjct: 180 QYMTNRAEHDRMARQWTK 197


>gi|4507779 ubiquitin-conjugating enzyme E2E 1 isoform 1 [Homo
           sapiens]
          Length = 193

 Score = 90.9 bits (224), Expect = 8e-19
 Identities = 47/138 (34%), Positives = 74/138 (53%)

Query: 16  VYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPP 75
           + KE+  +T DPP      P  +++ + + TI GP G+ Y GG+F + +    ++P  PP
Sbjct: 52  IQKELADITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPP 111

Query: 76  KGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGR 135
           K  F T+I+H N+ + G IC+++LK +W+  L I  VLL+I  LL   NP   L      
Sbjct: 112 KVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIAT 171

Query: 136 LLLENYEEYAARARLLTE 153
             + N  E+   AR  T+
Sbjct: 172 QYMTNRAEHDRMARQWTK 189


>gi|35494003 ubiquitin-conjugating enzyme E2I [Homo sapiens]
          Length = 158

 Score = 89.7 bits (221), Expect = 2e-18
 Identities = 47/131 (35%), Positives = 74/131 (56%), Gaps = 7/131 (5%)

Query: 26  DPPDGIKVFPNEE-----DLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFL 80
           D P G    P +      +L + +  I G +GTP+ GGLF++++L   D+P+SPPK  F 
Sbjct: 19  DHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFE 78

Query: 81  TKIFHPNVGANGEICVNVLK--RDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLL 138
             +FHPNV  +G +C+++L+  +DW   + I+ +LL I+ LL  PN +     EA  +  
Sbjct: 79  PPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYC 138

Query: 139 ENYEEYAARAR 149
           +N  EY  R R
Sbjct: 139 QNRVEYEKRVR 149


>gi|35493996 ubiquitin-conjugating enzyme E2I [Homo sapiens]
          Length = 158

 Score = 89.7 bits (221), Expect = 2e-18
 Identities = 47/131 (35%), Positives = 74/131 (56%), Gaps = 7/131 (5%)

Query: 26  DPPDGIKVFPNEE-----DLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFL 80
           D P G    P +      +L + +  I G +GTP+ GGLF++++L   D+P+SPPK  F 
Sbjct: 19  DHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFE 78

Query: 81  TKIFHPNVGANGEICVNVLK--RDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLL 138
             +FHPNV  +G +C+++L+  +DW   + I+ +LL I+ LL  PN +     EA  +  
Sbjct: 79  PPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYC 138

Query: 139 ENYEEYAARAR 149
           +N  EY  R R
Sbjct: 139 QNRVEYEKRVR 149


>gi|35493987 ubiquitin-conjugating enzyme E2I [Homo sapiens]
          Length = 158

 Score = 89.7 bits (221), Expect = 2e-18
 Identities = 47/131 (35%), Positives = 74/131 (56%), Gaps = 7/131 (5%)

Query: 26  DPPDGIKVFPNEE-----DLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFL 80
           D P G    P +      +L + +  I G +GTP+ GGLF++++L   D+P+SPPK  F 
Sbjct: 19  DHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFE 78

Query: 81  TKIFHPNVGANGEICVNVLK--RDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLL 138
             +FHPNV  +G +C+++L+  +DW   + I+ +LL I+ LL  PN +     EA  +  
Sbjct: 79  PPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYC 138

Query: 139 ENYEEYAARAR 149
           +N  EY  R R
Sbjct: 139 QNRVEYEKRVR 149


>gi|4507785 ubiquitin-conjugating enzyme E2I [Homo sapiens]
          Length = 158

 Score = 89.7 bits (221), Expect = 2e-18
 Identities = 47/131 (35%), Positives = 74/131 (56%), Gaps = 7/131 (5%)

Query: 26  DPPDGIKVFPNEE-----DLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFL 80
           D P G    P +      +L + +  I G +GTP+ GGLF++++L   D+P+SPPK  F 
Sbjct: 19  DHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFE 78

Query: 81  TKIFHPNVGANGEICVNVLK--RDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLL 138
             +FHPNV  +G +C+++L+  +DW   + I+ +LL I+ LL  PN +     EA  +  
Sbjct: 79  PPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYC 138

Query: 139 ENYEEYAARAR 149
           +N  EY  R R
Sbjct: 139 QNRVEYEKRVR 149


>gi|163660385 ubiquitin-conjugating enzyme E2K isoform 2 [Homo
           sapiens]
          Length = 157

 Score = 88.2 bits (217), Expect = 5e-18
 Identities = 44/121 (36%), Positives = 74/121 (61%), Gaps = 1/121 (0%)

Query: 7   NLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLL 66
           N+    I+  +KEV        + IKV   +E+ T+L+  I GP  TPY GG +++++ +
Sbjct: 3   NIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKI 62

Query: 67  GKDFPASPPKGYFLTKIFHPNVGA-NGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNP 125
            + +P +PPK  F+TKI+HPN+ +  G IC+++LK  W A + +R VLL+++ LL    P
Sbjct: 63  PETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEP 122

Query: 126 E 126
           +
Sbjct: 123 D 123


>gi|29893557 ubiquitin-conjugating enzyme E2G 2 isoform 1 [Homo
           sapiens]
          Length = 165

 Score = 84.0 bits (206), Expect = 1e-16
 Identities = 45/155 (29%), Positives = 80/155 (51%), Gaps = 14/155 (9%)

Query: 13  IRLVYKEVTTLTADPPDGIKVFP-NEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFP 71
           ++ +  E   LT +PP+GI   P NEE+  + +  I GPE T +  G+F   L    D+P
Sbjct: 6   LKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYP 65

Query: 72  ASPPKGYFLTKIFHPNVGANGEICVNVL-------------KRDWTAELGIRHVLLTIKC 118
            SPPK  F  ++FHPN+  +G +C+++L                W+    +  +LL++  
Sbjct: 66  LSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVS 125

Query: 119 LLIHPNPESALNEEAGRLLLENYEEYAARARLLTE 153
           +L  PN ES  N +A ++  ++ E++   A+ + +
Sbjct: 126 MLAEPNDESGANVDASKMWRDDREQFYKIAKQIVQ 160


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.136    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,514,521
Number of Sequences: 37866
Number of extensions: 557486
Number of successful extensions: 5858
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 195
Number of HSP's successfully gapped in prelim test: 161
Number of HSP's that attempted gapping in prelim test: 3352
Number of HSP's gapped (non-prelim): 2521
length of query: 222
length of database: 18,247,518
effective HSP length: 98
effective length of query: 124
effective length of database: 14,536,650
effective search space: 1802544600
effective search space used: 1802544600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.