Search of human proteins with 110825978

Search of human proteins with 110825978

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110825978 DNA-damage regulated autophagy modulator 1 [Homo
sapiens]
         (238 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110825978 DNA-damage regulated autophagy modulator 1 [Homo sa...   483   e-137
gi|166235182 transmembrane protein 77 [Homo sapiens]                  189   1e-48
gi|148232433 transmembrane protein 150B [Homo sapiens]                 74   8e-14
gi|72534762 transmembrane protein 150A isoform 1 [Homo sapiens]        69   3e-12
gi|122937458 hypothetical protein LOC441027 [Homo sapiens]             66   3e-11
gi|23503273 transmembrane protein 150A isoform 2 [Homo sapiens]        47   2e-05
gi|226246554 hypothetical protein LOC643677 [Homo sapiens]             32   0.63 
gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sap...    32   0.63 
gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sap...    32   0.63 
gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sap...    32   0.63 
gi|13236579 solute carrier family 27 member 3 [Homo sapiens]           30   1.8  
gi|157502171 sorting nexin 19 [Homo sapiens]                           29   3.1  
gi|16418361 RFT1 homolog [Homo sapiens]                                29   4.1  
gi|13236549 major facilitator superfamily domain containing 11 [...    29   4.1  
gi|116256487 patatin-like phospholipase domain containing 6 [Hom...    28   5.3  
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       28   7.0  
gi|42734401 testis-specific serine kinase 4 [Homo sapiens]             28   7.0  
gi|148727335 patatin-like phospholipase domain containing 7 isof...    28   9.1  
gi|148727290 patatin-like phospholipase domain containing 7 isof...    28   9.1  
gi|5453956 epsilon isoform of regulatory subunit B56, protein ph...    28   9.1  

>gi|110825978 DNA-damage regulated autophagy modulator 1 [Homo
           sapiens]
          Length = 238

 Score =  483 bits (1243), Expect = e-137
 Identities = 238/238 (100%), Positives = 238/238 (100%)

Query: 1   MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMI 60
           MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMI
Sbjct: 1   MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMI 60

Query: 61  NFSAFLGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVPV 120
           NFSAFLGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVPV
Sbjct: 61  NFSAFLGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVPV 120

Query: 121 VHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHIRMVISAVSCAAVIPMIVCASL 180
           VHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHIRMVISAVSCAAVIPMIVCASL
Sbjct: 121 VHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHIRMVISAVSCAAVIPMIVCASL 180

Query: 181 ISITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRISTEINGDI 238
           ISITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRISTEINGDI
Sbjct: 181 ISITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRISTEINGDI 238


>gi|166235182 transmembrane protein 77 [Homo sapiens]
          Length = 266

 Score =  189 bits (481), Expect = 1e-48
 Identities = 96/244 (39%), Positives = 147/244 (60%), Gaps = 9/244 (3%)

Query: 1   MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMI 60
           M  F +G++F+P  LV W+SAAFI SY+ AV   H++P LPYISDTGT  PE  +FG M+
Sbjct: 1   MWWFQQGLSFLPSALVIWTSAAFIFSYITAVTLHHIDPALPYISDTGTVAPEKCLFGAML 60

Query: 61  NFSAFLGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVPV 120
           N +A L  AT+Y RYK V   +        + N   LVLG++ C G+ IVANFQ+  +  
Sbjct: 61  NIAAVLCIATIYVRYKQVHALSPEENVIIKL-NKAGLVLGILSCLGLSIVANFQKTTLFA 119

Query: 121 VHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHIRMVISAVSCAAVIPMIVCASL 180
            H  GA+L F  G +Y  +Q+I+SY+  P+ +      IR+++      + + M+ C+S+
Sbjct: 120 AHVSGAVLTFGMGSLYMFVQTILSYQMQPKIHGKQVFWIRLLLVIWCGVSALSMLTCSSV 179

Query: 181 ISI--------TKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRIST 232
           +           KL WNP +K YV H+++   EW+++F F  +FLT+I+DFQ ++LR+  
Sbjct: 180 LHSGNFGTDLEQKLHWNPEDKGYVLHMITTAAEWSMSFSFFGFFLTYIRDFQKISLRVEA 239

Query: 233 EING 236
            ++G
Sbjct: 240 NLHG 243


>gi|148232433 transmembrane protein 150B [Homo sapiens]
          Length = 233

 Score = 74.3 bits (181), Expect = 8e-14
 Identities = 66/224 (29%), Positives = 97/224 (43%), Gaps = 27/224 (12%)

Query: 8   MAFVPFLLVTWSSAAFIISYVVAVLSGHVN--PFLPYISDTGTTPPESGIFGFMINFSAF 65
           ++ +P  L  W+ +   I + +AV +  V+     PYIS  G+ PP+S IF  ++N  A 
Sbjct: 5   LSLMPVFLAVWAISGVWIVFAIAVTNRTVDLSKGFPYISICGSFPPQSCIFSQVLNMGAA 64

Query: 66  LGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVPVVHDGG 125
           L A     RY  ++      +      N + L  GL+   G  +V NFQE      H  G
Sbjct: 65  LAAWICIVRYHQLRDWGVRRWP-----NQLILWTGLLCALGTSVVGNFQEKNQRPTHLAG 119

Query: 126 ALLAFVCGVVYTLLQSII-SYKSCPQWNSLSTCHIRMVISAVSCAAVIPMIV--CASLIS 182
           A LAF+ G VY  LQ ++   K  PQ  +     +R+ + +V    ++ MIV    SL S
Sbjct: 120 AFLAFILGNVYFWLQLLLWRLKRLPQPGAAWIGPLRLGLCSVCTILIVAMIVLHACSLRS 179

Query: 183 ITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQSV 226
                            VSA CEW VA      F     DF ++
Sbjct: 180 -----------------VSAACEWVVAMLLFALFGLLAVDFSAL 206


>gi|72534762 transmembrane protein 150A isoform 1 [Homo sapiens]
          Length = 271

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 48/188 (25%), Positives = 88/188 (46%), Gaps = 17/188 (9%)

Query: 40  LPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVL 99
           +P IS  G+ PPES +F  + N  AF+ A     RY  + +Q++  + +T      +L+ 
Sbjct: 63  VPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNT-----TALIT 117

Query: 100 GLVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHI 159
           G     G+ +V NFQ      +H  GA +AF  G+++  L   +SY+       L+  ++
Sbjct: 118 GCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAVAYL 177

Query: 160 RMVISAVSCAAVIPMIVCASLISITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTF 219
           R V++ +   A I +++               E   + H  +A+CEW      + ++ TF
Sbjct: 178 RSVLAVI---AFITLVLSGVFF--------VHESSQLQH-GAALCEWVCVIDILIFYGTF 225

Query: 220 IQDFQSVT 227
             +F +V+
Sbjct: 226 SYEFGAVS 233


>gi|122937458 hypothetical protein LOC441027 [Homo sapiens]
          Length = 249

 Score = 65.9 bits (159), Expect = 3e-11
 Identities = 57/227 (25%), Positives = 97/227 (42%), Gaps = 33/227 (14%)

Query: 10  FVPFLLVTWSSAAFIISYVVAVLSGHVNPF-----------LPYISDTGTTPPESGIFGF 58
           F+P +   ++SA   I Y +AV    + P             PYIS  G  PP S +F  
Sbjct: 11  FLPLVFTLFTSAGLWIVYFIAVEDDKILPLNSAERKPGVKHAPYISIAGDDPPASCVFSQ 70

Query: 59  MINFSAFLGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAV 118
           ++N +AFL       R+  +Q + +      P  N+  LV   +  FGM ++ NFQ    
Sbjct: 71  VMNMAAFLALVVAVLRF--IQLKPKVL---NPWLNISGLVALCLASFGMTLLGNFQLTND 125

Query: 119 PVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHIRMVISA-VSCAAVIPMIVC 177
             +H+ G  L F  G +   +Q+ ++ K   +         R+++SA ++   V+  I+ 
Sbjct: 126 EEIHNVGTSLTFGFGTLTCWIQAALTLKVNIKNEGRRVGIPRVILSASITLCVVLYFILM 185

Query: 178 ASLISITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQ 224
           A  I                H+ +A  +W +   F+ YF TF  +F+
Sbjct: 186 AQSI----------------HMYAARVQWGLVMCFLSYFGTFAVEFR 216


>gi|23503273 transmembrane protein 150A isoform 2 [Homo sapiens]
          Length = 218

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 12/135 (8%)

Query: 93  NLVSLVLGLVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWN 152
           N  +L+ G     G+ +V NFQ      +H  GA +AF  G+++  L   +SY+      
Sbjct: 58  NTTALITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPL 117

Query: 153 SLSTCHIRMVISAVSCAAVIPMIVCASLISITKLEWNPREKDYVYHVVSAICEWTVAFGF 212
            L+  ++R V++ +   A I +++               E   + H  +A+CEW      
Sbjct: 118 DLAVAYLRSVLAVI---AFITLVLSGVFF--------VHESSQLQH-GAALCEWVCVIDI 165

Query: 213 IFYFLTFIQDFQSVT 227
             ++ TF  +F +V+
Sbjct: 166 PIFYGTFSYEFGAVS 180


>gi|226246554 hypothetical protein LOC643677 [Homo sapiens]
          Length = 7081

 Score = 31.6 bits (70), Expect = 0.63
 Identities = 13/34 (38%), Positives = 20/34 (58%)

Query: 171  VIPMIVCASLISITKLEWNPREKDYVYHVVSAIC 204
            V+   +CAS++S   LEWNPR K+     ++  C
Sbjct: 3849 VVQNKLCASILSPPHLEWNPRIKEVYMRGITRFC 3882


>gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
          Length = 6929

 Score = 31.6 bits (70), Expect = 0.63
 Identities = 13/34 (38%), Positives = 20/34 (58%)

Query: 171  VIPMIVCASLISITKLEWNPREKDYVYHVVSAIC 204
            V+   +CAS++S   LEWNPR K+     ++  C
Sbjct: 3778 VVQNKLCASILSPPHLEWNPRIKEVYMRGITRFC 3811


>gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
          Length = 6929

 Score = 31.6 bits (70), Expect = 0.63
 Identities = 13/34 (38%), Positives = 20/34 (58%)

Query: 171  VIPMIVCASLISITKLEWNPREKDYVYHVVSAIC 204
            V+   +CAS++S   LEWNPR K+     ++  C
Sbjct: 3778 VVQNKLCASILSPPHLEWNPRIKEVYMRGITRFC 3811


>gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
          Length = 6929

 Score = 31.6 bits (70), Expect = 0.63
 Identities = 13/34 (38%), Positives = 20/34 (58%)

Query: 171  VIPMIVCASLISITKLEWNPREKDYVYHVVSAIC 204
            V+   +CAS++S   LEWNPR K+     ++  C
Sbjct: 3778 VVQNKLCASILSPPHLEWNPRIKEVYMRGITRFC 3811


>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
          Length = 730

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 10/28 (35%), Positives = 18/28 (64%)

Query: 81  QNQTCYFSTPVFNLVSLVLGLVGCFGMG 108
           Q    Y + P++++   +LG+VGC G+G
Sbjct: 366 QEDVIYLALPLYHMSGSLLGIVGCMGIG 393


>gi|157502171 sorting nexin 19 [Homo sapiens]
          Length = 992

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 16/57 (28%), Positives = 29/57 (50%), Gaps = 5/57 (8%)

Query: 119 PVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHIRMVISAVSCAAVIPMI 175
           P VH   A + +  GVV  LLQ ++     P   + +  H+  V+  ++C  ++P+I
Sbjct: 200 PAVHSPSAEVTYTRGVVNLLLQGLVPK---PHLETRTGRHV--VVELITCNVILPLI 251


>gi|16418361 RFT1 homolog [Homo sapiens]
          Length = 541

 Score = 28.9 bits (63), Expect = 4.1
 Identities = 44/221 (19%), Positives = 83/221 (37%), Gaps = 30/221 (13%)

Query: 11  VPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMINFSAFLGAAT 70
           V F L+T+   AFI+ ++   + G VN  L  +  T             +   AF  A  
Sbjct: 22  VLFRLITFVLNAFILRFLSKEIVGVVNVRLTLLYST----------TLFLAREAFRRACL 71

Query: 71  MYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVPVVHDGGALLAF 130
                +   +     + + P+    SL LG +           Q L VP   D   +  +
Sbjct: 72  SGGTQRDWSQTLNLLWLTVPLGVFWSLFLGWIW---------LQLLEVP---DPNVVPHY 119

Query: 131 VCGVVYTLLQSIISYKSCPQWNSLSTCH--IRMVISAVSCAAVIPMIVCASLISITKLEW 188
             GVV   L +++     P W  L+  H  +++ + A S + ++  ++ A L+      W
Sbjct: 120 ATGVVLFGLSAVVELLGEPFW-VLAQAHMFVKLKVIAESLSVILKSVLTAFLVL-----W 173

Query: 189 NPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLR 229
            P    Y++ +        +   ++ YF   +   +S  L+
Sbjct: 174 LPHWGLYIFSLAQLFYTTVLVLCYVIYFTKLLGSPESTKLQ 214


>gi|13236549 major facilitator superfamily domain containing 11
           [Homo sapiens]
          Length = 449

 Score = 28.9 bits (63), Expect = 4.1
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 6/88 (6%)

Query: 18  WS--SAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRY 75
           WS  +A+  I    AVL       L   SD  +    SGIF  ++  S F G   +Y  +
Sbjct: 99  WSFYTASVFIGIAAAVLWTAQGNCLTINSDEHSIGRNSGIFWALLQSSLFFGNLYIYFAW 158

Query: 76  ----KIVQKQNQTCYFSTPVFNLVSLVL 99
               +I +   +T + +  V +LV  VL
Sbjct: 159 QGKTQISESDRRTVFIALTVISLVGTVL 186


>gi|116256487 patatin-like phospholipase domain containing 6 [Homo
           sapiens]
          Length = 1327

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 3/47 (6%)

Query: 93  NLVSLVLG---LVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVY 136
           N ++LVLG     GC  +G++   +E  VPV   GG  +    G +Y
Sbjct: 929 NTIALVLGGGGARGCSHIGVLKALEEAGVPVDLVGGTSIGSFIGALY 975


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 28.1 bits (61), Expect = 7.0
 Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 96  SLVLGLVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVYT--LLQSIISYKSCPQWNS 153
           S++L  + C G    A     A P++H   A  A++   V+T  + QS I   S  QW S
Sbjct: 868 SVLLRELACAGNVADATLSAQATPLLHALTAAHAYIMMFVHTCRVGQSEIRSISVNQWGS 927

Query: 154 LSTCHIRMVISAVSCAAVIPMIVCASLISITKL 186
                +   +S + C+ V    V  SL +   L
Sbjct: 928 QLGLSVLSKLSQLYCSLVWESTVLLSLCTPNSL 960


>gi|42734401 testis-specific serine kinase 4 [Homo sapiens]
          Length = 328

 Score = 28.1 bits (61), Expect = 7.0
 Identities = 13/28 (46%), Positives = 17/28 (60%)

Query: 5   LRGMAFVPFLLVTWSSAAFIISYVVAVL 32
           LRG+ + PFL  TWS    + + VVA L
Sbjct: 210 LRGLPYNPFLSDTWSMGVILYTLVVAHL 237


>gi|148727335 patatin-like phospholipase domain containing 7 isoform
           a [Homo sapiens]
          Length = 1342

 Score = 27.7 bits (60), Expect = 9.1
 Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 3/48 (6%)

Query: 93  NLVSLVLG---LVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVYT 137
           N ++LVLG     GC  +G++    E  +PV   GG  +    G +Y+
Sbjct: 949 NAIALVLGGGGARGCAQVGVLKALAECGIPVDMVGGTSIGAFVGALYS 996


>gi|148727290 patatin-like phospholipase domain containing 7 isoform
           b [Homo sapiens]
          Length = 1317

 Score = 27.7 bits (60), Expect = 9.1
 Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 3/48 (6%)

Query: 93  NLVSLVLG---LVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVYT 137
           N ++LVLG     GC  +G++    E  +PV   GG  +    G +Y+
Sbjct: 924 NAIALVLGGGGARGCAQVGVLKALAECGIPVDMVGGTSIGAFVGALYS 971


>gi|5453956 epsilon isoform of regulatory subunit B56, protein
           phosphatase 2A [Homo sapiens]
          Length = 467

 Score = 27.7 bits (60), Expect = 9.1
 Identities = 15/35 (42%), Positives = 20/35 (57%)

Query: 171 VIPMIVCASLISITKLEWNPREKDYVYHVVSAICE 205
           VI  I+ +SL  I+K  WNP     VY+V+ A  E
Sbjct: 382 VILPIMFSSLYRISKEHWNPAIVALVYNVLKAFME 416


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.141    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,464,119
Number of Sequences: 37866
Number of extensions: 332159
Number of successful extensions: 773
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 749
Number of HSP's gapped (non-prelim): 21
length of query: 238
length of database: 18,247,518
effective HSP length: 99
effective length of query: 139
effective length of database: 14,498,784
effective search space: 2015330976
effective search space used: 2015330976
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.