Search of human proteins with 167830477

Search of human proteins with 167830477

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|167830477 milk fat globule-EGF factor 8 protein isoform b
[Homo sapiens]
         (335 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|167830477 milk fat globule-EGF factor 8 protein isoform b [Ho...   714   0.0  
gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Ho...   689   0.0  
gi|31317224 EGF-like repeats and discoidin I-like domains-contai...   311   7e-85
gi|105990535 coagulation factor V precursor [Homo sapiens]            194   7e-50
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap...   176   3e-44
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]           124   9e-29
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]           124   9e-29
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]           124   9e-29
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]           124   9e-29
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]           124   9e-29
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]           120   2e-27
gi|10518506 coagulation factor VIII isoform b precursor [Homo sa...   119   5e-27
gi|66864913 neuropilin 1 isoform c [Homo sapiens]                     115   7e-26
gi|66912178 neuropilin 1 isoform b [Homo sapiens]                     115   7e-26
gi|182508169 neuropilin 1 isoform a [Homo sapiens]                    115   7e-26
gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sa...    87   3e-17
gi|10835083 X-linked juvenile retinoschisis protein precursor [H...    80   3e-15
gi|27735143 discoidin, CUB and LCCL domain containing 1 [Homo sa...    72   5e-13
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap...    70   3e-12
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo...    69   8e-12
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi...    67   2e-11
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]       59   5e-09
gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2...    59   6e-09
gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1...    59   6e-09
gi|239743729 PREDICTED: similar to contactin associated protein-...    58   1e-08
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]            58   1e-08
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap...    52   1e-06
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap...    52   1e-06
gi|62420886 discoidin domain receptor family, member 2 precursor...    51   2e-06
gi|62420884 discoidin domain receptor family, member 2 precursor...    51   2e-06

>gi|167830477 milk fat globule-EGF factor 8 protein isoform b [Homo
           sapiens]
          Length = 335

 Score =  714 bits (1842), Expect = 0.0
 Identities = 335/335 (100%), Positives = 335/335 (100%)

Query: 1   MPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKG 60
           MPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKG
Sbjct: 1   MPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKG 60

Query: 61  YAGNHCETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPS 120
           YAGNHCETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPS
Sbjct: 61  YAGNHCETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPS 120

Query: 121 SNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHK 180
           SNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHK
Sbjct: 121 SNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHK 180

Query: 181 EFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNS 240
           EFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNS
Sbjct: 181 EFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNS 240

Query: 241 IPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQIFPGNWDNHS 300
           IPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQIFPGNWDNHS
Sbjct: 241 IPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQIFPGNWDNHS 300

Query: 301 HKKNLFETPILARYVRILPVAWHNRIALRLELLGC 335
           HKKNLFETPILARYVRILPVAWHNRIALRLELLGC
Sbjct: 301 HKKNLFETPILARYVRILPVAWHNRIALRLELLGC 335


>gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Homo
           sapiens]
          Length = 387

 Score =  689 bits (1779), Expect = 0.0
 Identities = 335/387 (86%), Positives = 335/387 (86%), Gaps = 52/387 (13%)

Query: 1   MPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKG 60
           MPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKG
Sbjct: 1   MPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKG 60

Query: 61  YAGNHCETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPS 120
           YAGNHCETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPS
Sbjct: 61  YAGNHCETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPS 120

Query: 121 SNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHK 180
           SNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHK
Sbjct: 121 SNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHK 180

Query: 181 EFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNS 240
           EFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNS
Sbjct: 181 EFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNS 240

Query: 241 IPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQ---------- 290
           IPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQ          
Sbjct: 241 IPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVT 300

Query: 291 ------------------------------------------IFPGNWDNHSHKKNLFET 308
                                                     IFPGNWDNHSHKKNLFET
Sbjct: 301 GIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWDNHSHKKNLFET 360

Query: 309 PILARYVRILPVAWHNRIALRLELLGC 335
           PILARYVRILPVAWHNRIALRLELLGC
Sbjct: 361 PILARYVRILPVAWHNRIALRLELLGC 387


>gi|31317224 EGF-like repeats and discoidin I-like
           domains-containing protein 3 [Homo sapiens]
          Length = 480

 Score =  311 bits (796), Expect = 7e-85
 Identities = 166/401 (41%), Positives = 216/401 (53%), Gaps = 94/401 (23%)

Query: 27  CSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKGYAGNHCET------------------ 68
           C+ NPCHNGG CE IS+  RGD F  Y C C +G+ G HC+                   
Sbjct: 78  CTPNPCHNGGTCE-ISEAYRGDTFIGYVCKCPRGFNGIHCQHNINECEVEPCKNGGICTD 136

Query: 69  --------------------KCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARL 108
                               KC  PLG+E G I+N QI ASS      GLQ W P  ARL
Sbjct: 137 LVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARL 196

Query: 109 NRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHE 168
           N+ G++NAWT + ND  PWIQ+NL R+M VTGV+TQGA R+ S EY+K++K+AYS +G  
Sbjct: 197 NKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKT 256

Query: 169 FDFIHDVNKKHKEFV--GNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCE 226
           +  ++ V   +++ V  GN + N  + N F  P++AQYVRLYP  C   CTLR ELLGCE
Sbjct: 257 W-AMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCE 315

Query: 227 LNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGND 286
           L+GC+ PLG+K+  I D QITASS ++T  + +F+W P  ARLDKQG  NAW +G     
Sbjct: 316 LSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQS 375

Query: 287 QWLQ----------------------------------------------------IFPG 294
           QWLQ                                                    +F G
Sbjct: 376 QWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKDKVFQG 435

Query: 295 NWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 335
           N+DN +H+KN+ + PI AR++RILP +W+ RI LR ELLGC
Sbjct: 436 NFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGC 476


>gi|105990535 coagulation factor V precursor [Homo sapiens]
          Length = 2224

 Score =  194 bits (494), Expect = 7e-50
 Identities = 118/323 (36%), Positives = 159/323 (49%), Gaps = 65/323 (20%)

Query: 70   CVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWT----PSSNDDN 125
            C  P+GL  G I++SQI AS     FLG  +W P LARLN  G  NAW+     +     
Sbjct: 1907 CRMPMGLSTGIISDSQIKASE----FLG--YWEPRLARLNNGGSYNAWSVEKLAAEFASK 1960

Query: 126  PWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFD-FIHDVNKKHKEFVG 184
            PWIQV++ + + +TG+ TQGA       Y   F VAYS N   +  F  +  +    F G
Sbjct: 1961 PWIQVDMQKEVIITGIQTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNG 2020

Query: 185  NWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDK 244
            N + + +  N F+ P+ A+Y+R+ PT  +   TLR EL GCE+NGC+ PLG++N  I +K
Sbjct: 2021 NSDASTIKENQFDPPIVARYIRISPTRAYNRPTLRLELQGCEVNGCSTPLGMENGKIENK 2080

Query: 245  QITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQ-------------- 290
            QITASS  K+W      W P  ARL+ QG  NAW A +  N QWL+              
Sbjct: 2081 QITASSFKKSWWGDY--WEPFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIIT 2138

Query: 291  --------------------------------------IFPGNWDNHSHKKNLFETPILA 312
                                                  IF GN +   H KN F  PI++
Sbjct: 2139 QGCKSLSSEMYVKSYTIHYSEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIIS 2198

Query: 313  RYVRILPVAWHNRIALRLELLGC 335
            R++R++P  W+  IALRLEL GC
Sbjct: 2199 RFIRVIPKTWNQSIALRLELFGC 2221



 Score =  115 bits (289), Expect = 4e-26
 Identities = 60/164 (36%), Positives = 95/164 (57%), Gaps = 3/164 (1%)

Query: 66   CETK-CVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDD 124
            CE   C  PLG+ENG I N QI ASS + ++ G  +W P  ARLN  G VNAW   +N++
Sbjct: 2061 CEVNGCSTPLGMENGKIENKQITASSFKKSWWG-DYWEPFRARLNAQGRVNAWQAKANNN 2119

Query: 125  NPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEF-DFIHDVNKKHKEFV 183
              W++++LL+   +T ++TQG   L+S  Y+K++ + YS  G E+  +    +   K F 
Sbjct: 2120 KQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYTIHYSEQGVEWKPYRLKSSMVDKIFE 2179

Query: 184  GNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCEL 227
            GN N      N F  P+ ++++R+ P + + +  LR EL GC++
Sbjct: 2180 GNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSIALRLELFGCDI 2223


>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
          Length = 2351

 Score =  176 bits (446), Expect = 3e-44
 Identities = 108/318 (33%), Positives = 163/318 (51%), Gaps = 62/318 (19%)

Query: 69   KCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWI 128
            KC  PLG+ +G+I + QI AS           W P+LARL+ +G +NAW  S+ +   WI
Sbjct: 2039 KCQTPLGMASGHIRDFQITASGQ------YGQWAPKLARLHYSGSINAW--STKEPFSWI 2090

Query: 129  QVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFD-FIHDVNKKHKEFVGNWN 187
            +V+LL  M + G+ TQGA +  S  Y+  F + YSL+G ++  +  +       F GN +
Sbjct: 2091 KVDLLAPMIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNVD 2150

Query: 188  KNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQIT 247
             + +  N+F  P+ A+Y+RL+PT      TLR EL+GC+LN C+ PLG+++ +I D QIT
Sbjct: 2151 SSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESKAISDAQIT 2210

Query: 248  ASSSYKTWGLHLFSWNPSYARLDKQGNFNAW----------------------------- 278
            ASS +        +W+PS ARL  QG  NAW                             
Sbjct: 2211 ASSYFTNM---FATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGV 2267

Query: 279  -------------VAGSYGNDQW--------LQIFPGNWDNHSHKKNLFETPILARYVRI 317
                         ++ S    QW        +++F GN D+ +   N  + P+L RY+RI
Sbjct: 2268 KSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRI 2327

Query: 318  LPVAWHNRIALRLELLGC 335
             P +W ++IALR+E+LGC
Sbjct: 2328 HPQSWVHQIALRMEVLGC 2345



 Score =  106 bits (265), Expect = 3e-23
 Identities = 60/157 (38%), Positives = 85/157 (54%), Gaps = 3/157 (1%)

Query: 70   CVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQ 129
            C  PLG+E+  I+++QI ASS          W P  ARL+  G  NAW P  N+   W+Q
Sbjct: 2193 CSMPLGMESKAISDAQITASSYFTNMFAT--WSPSKARLHLQGRSNAWRPQVNNPKEWLQ 2250

Query: 130  VNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNWNKN 189
            V+  + M VTGV TQG   L +  Y+K F ++ S +GH++      N K K F GN +  
Sbjct: 2251 VDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQ-NGKVKVFQGNQDSF 2309

Query: 190  AVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCE 226
               VN  + P+  +Y+R++P S      LR E+LGCE
Sbjct: 2310 TPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 2346



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 46/158 (29%), Positives = 60/158 (37%), Gaps = 57/158 (36%)

Query: 228  NGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAW--------- 278
            N C  PLG+ +  I D QITAS  Y  W        P  ARL   G+ NAW         
Sbjct: 2038 NKCQTPLGMASGHIRDFQITASGQYGQWA-------PKLARLHYSGSINAWSTKEPFSWI 2090

Query: 279  -------------------------------VAGSYGNDQW----------LQIFPGNWD 297
                                           +  S    +W          L +F GN D
Sbjct: 2091 KVDLLAPMIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNVD 2150

Query: 298  NHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 335
            +   K N+F  PI+ARY+R+ P  +  R  LR+EL+GC
Sbjct: 2151 SSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGC 2188


>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
          Length = 909

 Score =  124 bits (312), Expect = 9e-29
 Identities = 96/330 (29%), Positives = 151/330 (45%), Gaps = 76/330 (23%)

Query: 69  KCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWI 128
           +C  PLG+E+G IAN QI+ASS          W P+ +RL+  G  N WTP+ + +  ++
Sbjct: 276 QCNVPLGMESGRIANEQISASSTYSD----GRWTPQQSRLH--GDDNGWTPNLDSNKEYL 329

Query: 129 QVNLLRRMWVTGVVTQGASRLASHE--YLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNW 186
           QV+L     +T + TQGA    +    Y+K++K+  S NG ++  ++   K HK F  N 
Sbjct: 330 QVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDW-MVYRHGKNHKVFQANN 388

Query: 187 NKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNG--CANPLGLKNNSIPDK 244
           +   V +N    P+  ++VR+ P + H+   LR EL GC +    C+N LG+ +  I D 
Sbjct: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIADS 448

Query: 245 QITASSSYKTWGLHLFSWNPSYARL-DKQGNFNAWVAGSYGNDQWLQIFPG--------- 294
           QI+ASS+ +      + W+PS ARL   +  +   +  +   ++WLQ+  G         
Sbjct: 449 QISASSTQE------YLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVI 502

Query: 295 -------------------------------NW----DNHSHKKNLFE------------ 307
                                          +W    D  + +  LFE            
Sbjct: 503 IQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDIRR 562

Query: 308 -TPILARYVRILPVAWHNR-IALRLELLGC 335
             PI A+YVR+ P  W    I +RLE+LGC
Sbjct: 563 FDPIPAQYVRVYPERWSPAGIGMRLEVLGC 592



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 59/170 (34%), Positives = 93/170 (54%), Gaps = 17/170 (10%)

Query: 67  ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARL--NRAGMVNAWTPSSNDD 124
           +  C   LG+ +G IA+SQI+ASS +        W P  ARL  +R+G      P +   
Sbjct: 431 DAPCSNMLGMLSGLIADSQISASSTQEYL-----WSPSAARLVSSRSGWFPR-IPQAQPG 484

Query: 125 NPWIQVNLLRRMWVTGVVTQGA------SRLASHEYLKAFKVAYSLNGHEFDFIHDV-NK 177
             W+QV+L     V GV+ QGA      + + +  +++ FKV+YSLNG ++++I D   +
Sbjct: 485 EEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544

Query: 178 KHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTA-CTLRFELLGCE 226
           + K F GN + +   +  F+ P+ AQYVR+YP     A   +R E+LGC+
Sbjct: 545 QPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAGIGMRLEVLGCD 593


>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
          Length = 901

 Score =  124 bits (312), Expect = 9e-29
 Identities = 96/330 (29%), Positives = 151/330 (45%), Gaps = 76/330 (23%)

Query: 69  KCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWI 128
           +C  PLG+E+G IAN QI+ASS          W P+ +RL+  G  N WTP+ + +  ++
Sbjct: 276 QCNVPLGMESGRIANEQISASSTYSD----GRWTPQQSRLH--GDDNGWTPNLDSNKEYL 329

Query: 129 QVNLLRRMWVTGVVTQGASRLASHE--YLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNW 186
           QV+L     +T + TQGA    +    Y+K++K+  S NG ++  ++   K HK F  N 
Sbjct: 330 QVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDW-MVYRHGKNHKVFQANN 388

Query: 187 NKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNG--CANPLGLKNNSIPDK 244
           +   V +N    P+  ++VR+ P + H+   LR EL GC +    C+N LG+ +  I D 
Sbjct: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIADS 448

Query: 245 QITASSSYKTWGLHLFSWNPSYARL-DKQGNFNAWVAGSYGNDQWLQIFPG--------- 294
           QI+ASS+ +      + W+PS ARL   +  +   +  +   ++WLQ+  G         
Sbjct: 449 QISASSTQE------YLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVI 502

Query: 295 -------------------------------NW----DNHSHKKNLFE------------ 307
                                          +W    D  + +  LFE            
Sbjct: 503 IQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDIRR 562

Query: 308 -TPILARYVRILPVAWHNR-IALRLELLGC 335
             PI A+YVR+ P  W    I +RLE+LGC
Sbjct: 563 FDPIPAQYVRVYPERWSPAGIGMRLEVLGC 592



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 59/170 (34%), Positives = 93/170 (54%), Gaps = 17/170 (10%)

Query: 67  ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARL--NRAGMVNAWTPSSNDD 124
           +  C   LG+ +G IA+SQI+ASS +        W P  ARL  +R+G      P +   
Sbjct: 431 DAPCSNMLGMLSGLIADSQISASSTQEYL-----WSPSAARLVSSRSGWFPR-IPQAQPG 484

Query: 125 NPWIQVNLLRRMWVTGVVTQGA------SRLASHEYLKAFKVAYSLNGHEFDFIHDV-NK 177
             W+QV+L     V GV+ QGA      + + +  +++ FKV+YSLNG ++++I D   +
Sbjct: 485 EEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544

Query: 178 KHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTA-CTLRFELLGCE 226
           + K F GN + +   +  F+ P+ AQYVR+YP     A   +R E+LGC+
Sbjct: 545 QPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAGIGMRLEVLGCD 593


>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
          Length = 931

 Score =  124 bits (312), Expect = 9e-29
 Identities = 96/330 (29%), Positives = 151/330 (45%), Gaps = 76/330 (23%)

Query: 69  KCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWI 128
           +C  PLG+E+G IAN QI+ASS          W P+ +RL+  G  N WTP+ + +  ++
Sbjct: 276 QCNVPLGMESGRIANEQISASSTYSD----GRWTPQQSRLH--GDDNGWTPNLDSNKEYL 329

Query: 129 QVNLLRRMWVTGVVTQGASRLASHE--YLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNW 186
           QV+L     +T + TQGA    +    Y+K++K+  S NG ++  ++   K HK F  N 
Sbjct: 330 QVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDW-MVYRHGKNHKVFQANN 388

Query: 187 NKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNG--CANPLGLKNNSIPDK 244
           +   V +N    P+  ++VR+ P + H+   LR EL GC +    C+N LG+ +  I D 
Sbjct: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIADS 448

Query: 245 QITASSSYKTWGLHLFSWNPSYARL-DKQGNFNAWVAGSYGNDQWLQIFPG--------- 294
           QI+ASS+ +      + W+PS ARL   +  +   +  +   ++WLQ+  G         
Sbjct: 449 QISASSTQE------YLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVI 502

Query: 295 -------------------------------NW----DNHSHKKNLFE------------ 307
                                          +W    D  + +  LFE            
Sbjct: 503 IQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDIRR 562

Query: 308 -TPILARYVRILPVAWHNR-IALRLELLGC 335
             PI A+YVR+ P  W    I +RLE+LGC
Sbjct: 563 FDPIPAQYVRVYPERWSPAGIGMRLEVLGC 592



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 59/170 (34%), Positives = 93/170 (54%), Gaps = 17/170 (10%)

Query: 67  ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARL--NRAGMVNAWTPSSNDD 124
           +  C   LG+ +G IA+SQI+ASS +        W P  ARL  +R+G      P +   
Sbjct: 431 DAPCSNMLGMLSGLIADSQISASSTQEYL-----WSPSAARLVSSRSGWFPR-IPQAQPG 484

Query: 125 NPWIQVNLLRRMWVTGVVTQGA------SRLASHEYLKAFKVAYSLNGHEFDFIHDV-NK 177
             W+QV+L     V GV+ QGA      + + +  +++ FKV+YSLNG ++++I D   +
Sbjct: 485 EEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544

Query: 178 KHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTA-CTLRFELLGCE 226
           + K F GN + +   +  F+ P+ AQYVR+YP     A   +R E+LGC+
Sbjct: 545 QPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAGIGMRLEVLGCD 593


>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
          Length = 906

 Score =  124 bits (312), Expect = 9e-29
 Identities = 96/330 (29%), Positives = 151/330 (45%), Gaps = 76/330 (23%)

Query: 69  KCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWI 128
           +C  PLG+E+G IAN QI+ASS          W P+ +RL+  G  N WTP+ + +  ++
Sbjct: 276 QCNVPLGMESGRIANEQISASSTYSD----GRWTPQQSRLH--GDDNGWTPNLDSNKEYL 329

Query: 129 QVNLLRRMWVTGVVTQGASRLASHE--YLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNW 186
           QV+L     +T + TQGA    +    Y+K++K+  S NG ++  ++   K HK F  N 
Sbjct: 330 QVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDW-MVYRHGKNHKVFQANN 388

Query: 187 NKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNG--CANPLGLKNNSIPDK 244
           +   V +N    P+  ++VR+ P + H+   LR EL GC +    C+N LG+ +  I D 
Sbjct: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIADS 448

Query: 245 QITASSSYKTWGLHLFSWNPSYARL-DKQGNFNAWVAGSYGNDQWLQIFPG--------- 294
           QI+ASS+ +      + W+PS ARL   +  +   +  +   ++WLQ+  G         
Sbjct: 449 QISASSTQE------YLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVI 502

Query: 295 -------------------------------NW----DNHSHKKNLFE------------ 307
                                          +W    D  + +  LFE            
Sbjct: 503 IQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDIRR 562

Query: 308 -TPILARYVRILPVAWHNR-IALRLELLGC 335
             PI A+YVR+ P  W    I +RLE+LGC
Sbjct: 563 FDPIPAQYVRVYPERWSPAGIGMRLEVLGC 592



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 59/170 (34%), Positives = 93/170 (54%), Gaps = 17/170 (10%)

Query: 67  ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARL--NRAGMVNAWTPSSNDD 124
           +  C   LG+ +G IA+SQI+ASS +        W P  ARL  +R+G      P +   
Sbjct: 431 DAPCSNMLGMLSGLIADSQISASSTQEYL-----WSPSAARLVSSRSGWFPR-IPQAQPG 484

Query: 125 NPWIQVNLLRRMWVTGVVTQGA------SRLASHEYLKAFKVAYSLNGHEFDFIHDV-NK 177
             W+QV+L     V GV+ QGA      + + +  +++ FKV+YSLNG ++++I D   +
Sbjct: 485 EEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544

Query: 178 KHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTA-CTLRFELLGCE 226
           + K F GN + +   +  F+ P+ AQYVR+YP     A   +R E+LGC+
Sbjct: 545 QPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAGIGMRLEVLGCD 593


>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
          Length = 926

 Score =  124 bits (312), Expect = 9e-29
 Identities = 96/330 (29%), Positives = 151/330 (45%), Gaps = 76/330 (23%)

Query: 69  KCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWI 128
           +C  PLG+E+G IAN QI+ASS          W P+ +RL+  G  N WTP+ + +  ++
Sbjct: 276 QCNVPLGMESGRIANEQISASSTYSD----GRWTPQQSRLH--GDDNGWTPNLDSNKEYL 329

Query: 129 QVNLLRRMWVTGVVTQGASRLASHE--YLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNW 186
           QV+L     +T + TQGA    +    Y+K++K+  S NG ++  ++   K HK F  N 
Sbjct: 330 QVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDW-MVYRHGKNHKVFQANN 388

Query: 187 NKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNG--CANPLGLKNNSIPDK 244
           +   V +N    P+  ++VR+ P + H+   LR EL GC +    C+N LG+ +  I D 
Sbjct: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIADS 448

Query: 245 QITASSSYKTWGLHLFSWNPSYARL-DKQGNFNAWVAGSYGNDQWLQIFPG--------- 294
           QI+ASS+ +      + W+PS ARL   +  +   +  +   ++WLQ+  G         
Sbjct: 449 QISASSTQE------YLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVI 502

Query: 295 -------------------------------NW----DNHSHKKNLFE------------ 307
                                          +W    D  + +  LFE            
Sbjct: 503 IQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDIRR 562

Query: 308 -TPILARYVRILPVAWHNR-IALRLELLGC 335
             PI A+YVR+ P  W    I +RLE+LGC
Sbjct: 563 FDPIPAQYVRVYPERWSPAGIGMRLEVLGC 592



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 59/170 (34%), Positives = 93/170 (54%), Gaps = 17/170 (10%)

Query: 67  ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARL--NRAGMVNAWTPSSNDD 124
           +  C   LG+ +G IA+SQI+ASS +        W P  ARL  +R+G      P +   
Sbjct: 431 DAPCSNMLGMLSGLIADSQISASSTQEYL-----WSPSAARLVSSRSGWFPR-IPQAQPG 484

Query: 125 NPWIQVNLLRRMWVTGVVTQGA------SRLASHEYLKAFKVAYSLNGHEFDFIHDV-NK 177
             W+QV+L     V GV+ QGA      + + +  +++ FKV+YSLNG ++++I D   +
Sbjct: 485 EEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544

Query: 178 KHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTA-CTLRFELLGCE 226
           + K F GN + +   +  F+ P+ AQYVR+YP     A   +R E+LGC+
Sbjct: 545 QPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAGIGMRLEVLGCD 593


>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
          Length = 555

 Score =  120 bits (301), Expect = 2e-27
 Identities = 75/228 (32%), Positives = 123/228 (53%), Gaps = 18/228 (7%)

Query: 69  KCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWI 128
           +C  PLG+E+G IAN QI+ASS          W P+ +RL+  G  N WTP+ + +  ++
Sbjct: 276 QCNVPLGMESGRIANEQISASSTYSD----GRWTPQQSRLH--GDDNGWTPNLDSNKEYL 329

Query: 129 QVNLLRRMWVTGVVTQGASRLASHE--YLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNW 186
           QV+L     +T + TQGA    +    Y+K++K+  S NG ++  ++   K HK F  N 
Sbjct: 330 QVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDW-MVYRHGKNHKVFQANN 388

Query: 187 NKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNG--CANPLGLKNNSIPDK 244
           +   V +N    P+  ++VR+ P + H+   LR EL GC +    C+N LG+ +  I D 
Sbjct: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIADS 448

Query: 245 QITASSSYKTWGLHLFSWNPSYARL-DKQGNFNAWVAGSYGNDQWLQI 291
           QI+ASS+ +      + W+PS ARL   +  +   +  +   ++WLQ+
Sbjct: 449 QISASSTQE------YLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQV 490



 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 41/128 (32%), Positives = 67/128 (52%), Gaps = 14/128 (10%)

Query: 67  ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARL--NRAGMVNAWTPSSNDD 124
           +  C   LG+ +G IA+SQI+ASS +        W P  ARL  +R+G      P +   
Sbjct: 431 DAPCSNMLGMLSGLIADSQISASSTQEYL-----WSPSAARLVSSRSGWFPR-IPQAQPG 484

Query: 125 NPWIQVNLLRRMWVTGVVTQGA------SRLASHEYLKAFKVAYSLNGHEFDFIHDVNKK 178
             W+QV+L     V GV+ QGA      + + +  +++ FKV+YSLNG ++++I D   +
Sbjct: 485 EEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544

Query: 179 HKEFVGNW 186
             +   +W
Sbjct: 545 QPKVGCSW 552



 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 43/158 (27%), Positives = 58/158 (36%), Gaps = 59/158 (37%)

Query: 230 CANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWL 289
           C  PLG+++  I ++QI+ASS+Y         W P  +RL   G+ N W      N ++L
Sbjct: 277 CNVPLGMESGRIANEQISASSTYSDG-----RWTPQQSRL--HGDDNGWTPNLDSNKEYL 329

Query: 290 QI----------------------------------------------------FPGNWD 297
           Q+                                                    F  N D
Sbjct: 330 QVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANND 389

Query: 298 NHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 335
                 N    P+L R+VRI P  WH+ IALRLEL GC
Sbjct: 390 ATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGC 427


>gi|10518506 coagulation factor VIII isoform b precursor [Homo
           sapiens]
          Length = 216

 Score =  119 bits (297), Expect = 5e-27
 Identities = 69/206 (33%), Positives = 102/206 (49%), Gaps = 53/206 (25%)

Query: 180 KEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNN 239
           K F GN + + +  N+F  P+ A+Y+RL+PT      TLR EL+GC+LN C+ PLG+++ 
Sbjct: 8   KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESK 67

Query: 240 SIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAW--------------------- 278
           +I D QITASS +        +W+PS ARL  QG  NAW                     
Sbjct: 68  AISDAQITASSYFTNM---FATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKV 124

Query: 279 ---------------------VAGSYGNDQW--------LQIFPGNWDNHSHKKNLFETP 309
                                ++ S    QW        +++F GN D+ +   N  + P
Sbjct: 125 TGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPP 184

Query: 310 ILARYVRILPVAWHNRIALRLELLGC 335
           +L RY+RI P +W ++IALR+E+LGC
Sbjct: 185 LLTRYLRIHPQSWVHQIALRMEVLGC 210



 Score =  106 bits (265), Expect = 3e-23
 Identities = 60/157 (38%), Positives = 85/157 (54%), Gaps = 3/157 (1%)

Query: 70  CVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQ 129
           C  PLG+E+  I+++QI ASS          W P  ARL+  G  NAW P  N+   W+Q
Sbjct: 58  CSMPLGMESKAISDAQITASSYFTNMFAT--WSPSKARLHLQGRSNAWRPQVNNPKEWLQ 115

Query: 130 VNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNWNKN 189
           V+  + M VTGV TQG   L +  Y+K F ++ S +GH++      N K K F GN +  
Sbjct: 116 VDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQ-NGKVKVFQGNQDSF 174

Query: 190 AVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCE 226
              VN  + P+  +Y+R++P S      LR E+LGCE
Sbjct: 175 TPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 211


>gi|66864913 neuropilin 1 isoform c [Homo sapiens]
          Length = 609

 Score =  115 bits (287), Expect = 7e-26
 Identities = 107/353 (30%), Positives = 158/353 (44%), Gaps = 81/353 (22%)

Query: 49  VFPSYTCTCLKGYAGNHC--------ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQH 100
           VF + +    +G++ N+         + KC+E LG+E+G I + QI ASS   T     +
Sbjct: 246 VFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYST-----N 300

Query: 101 WVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHE--YLKAF 158
           W  E +RLN     N WTP  +    WIQV+L    +VT V TQGA    + +  Y+K +
Sbjct: 301 WSAERSRLNYPE--NGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTY 358

Query: 159 KVAYSLNGHEFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTL 218
           K+  S NG ++  I + NK    F GN N   V V +F  P+  ++VR+ P +  T  ++
Sbjct: 359 KIDVSSNGEDWITIKEGNKPVL-FQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISM 417

Query: 219 RFELLGCELNG--CANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARL--DKQGN 274
           RFE+ GC++    C+  LG+ +  I D QIT+S+          +W P   RL   + G 
Sbjct: 418 RFEVYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDR------NWMPENIRLVTSRSGW 471

Query: 275 FNAWVAGSYGNDQWLQIFPG----------------------------------NW---- 296
                  SY N +WLQI  G                                  +W    
Sbjct: 472 ALPPAPHSYIN-EWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIM 530

Query: 297 DNHSHK------KNLFETPIL-------ARYVRILPV-AWHNRIALRLELLGC 335
           D+   K       N ++TP L        R++RI P  A H  + LR+ELLGC
Sbjct: 531 DDSKRKAKSFEGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGC 583



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 59/181 (32%), Positives = 95/181 (52%), Gaps = 11/181 (6%)

Query: 70  CVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARL--NRAGMVNAWTPSSNDDNPW 127
           C   LG+ +G I++SQI +S+      G ++W+PE  RL  +R+G      P S   N W
Sbjct: 431 CSGMLGMVSGLISDSQITSSNQ-----GDRNWMPENIRLVTSRSGWALPPAPHSYI-NEW 484

Query: 128 IQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNK-KHKEFVGNW 186
           +Q++L     V G++ QG     +  +++ FK+ YS NG ++  I D +K K K F GN 
Sbjct: 485 LQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNN 544

Query: 187 NKNAVHVNLFETPVEAQYVRLYP-TSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQ 245
           N +   +  F   +  +++R+YP  + H    LR ELLGCE+ G    L  +  ++ D  
Sbjct: 545 NYDTPELRTFPA-LSTRFIRIYPERATHGGLGLRMELLGCEVEGGTTVLATEKPTVIDST 603

Query: 246 I 246
           I
Sbjct: 604 I 604


>gi|66912178 neuropilin 1 isoform b [Homo sapiens]
          Length = 644

 Score =  115 bits (287), Expect = 7e-26
 Identities = 107/353 (30%), Positives = 158/353 (44%), Gaps = 81/353 (22%)

Query: 49  VFPSYTCTCLKGYAGNHC--------ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQH 100
           VF + +    +G++ N+         + KC+E LG+E+G I + QI ASS   T     +
Sbjct: 246 VFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYST-----N 300

Query: 101 WVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHE--YLKAF 158
           W  E +RLN     N WTP  +    WIQV+L    +VT V TQGA    + +  Y+K +
Sbjct: 301 WSAERSRLNYPE--NGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTY 358

Query: 159 KVAYSLNGHEFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTL 218
           K+  S NG ++  I + NK    F GN N   V V +F  P+  ++VR+ P +  T  ++
Sbjct: 359 KIDVSSNGEDWITIKEGNKPVL-FQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISM 417

Query: 219 RFELLGCELNG--CANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARL--DKQGN 274
           RFE+ GC++    C+  LG+ +  I D QIT+S+          +W P   RL   + G 
Sbjct: 418 RFEVYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDR------NWMPENIRLVTSRSGW 471

Query: 275 FNAWVAGSYGNDQWLQIFPG----------------------------------NW---- 296
                  SY N +WLQI  G                                  +W    
Sbjct: 472 ALPPAPHSYIN-EWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIM 530

Query: 297 DNHSHK------KNLFETPIL-------ARYVRILPV-AWHNRIALRLELLGC 335
           D+   K       N ++TP L        R++RI P  A H  + LR+ELLGC
Sbjct: 531 DDSKRKAKSFEGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGC 583



 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 61/189 (32%), Positives = 95/189 (50%), Gaps = 15/189 (7%)

Query: 70  CVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARL--NRAGMVNAWTPSSNDDNPW 127
           C   LG+ +G I++SQI +S+      G ++W+PE  RL  +R+G      P S   N W
Sbjct: 431 CSGMLGMVSGLISDSQITSSNQ-----GDRNWMPENIRLVTSRSGWALPPAPHSYI-NEW 484

Query: 128 IQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNK-KHKEFVGNW 186
           +Q++L     V G++ QG     +  +++ FK+ YS NG ++  I D +K K K F GN 
Sbjct: 485 LQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNN 544

Query: 187 NKNAVHVNLFETPVEAQYVRLYP-TSCHTACTLRFELLGCELN----GCANPLGLKNNSI 241
           N +   +  F   +  +++R+YP  + H    LR ELLGCE+     G   P G   +  
Sbjct: 545 NYDTPELRTFPA-LSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLVDEC 603

Query: 242 PDKQITASS 250
            D Q    S
Sbjct: 604 DDDQANCHS 612


>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
          Length = 923

 Score =  115 bits (287), Expect = 7e-26
 Identities = 107/353 (30%), Positives = 158/353 (44%), Gaps = 81/353 (22%)

Query: 49  VFPSYTCTCLKGYAGNHC--------ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQH 100
           VF + +    +G++ N+         + KC+E LG+E+G I + QI ASS   T     +
Sbjct: 246 VFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYST-----N 300

Query: 101 WVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHE--YLKAF 158
           W  E +RLN     N WTP  +    WIQV+L    +VT V TQGA    + +  Y+K +
Sbjct: 301 WSAERSRLNYPE--NGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTY 358

Query: 159 KVAYSLNGHEFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTL 218
           K+  S NG ++  I + NK    F GN N   V V +F  P+  ++VR+ P +  T  ++
Sbjct: 359 KIDVSSNGEDWITIKEGNKPVL-FQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISM 417

Query: 219 RFELLGCELNG--CANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARL--DKQGN 274
           RFE+ GC++    C+  LG+ +  I D QIT+S+          +W P   RL   + G 
Sbjct: 418 RFEVYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDR------NWMPENIRLVTSRSGW 471

Query: 275 FNAWVAGSYGNDQWLQIFPG----------------------------------NW---- 296
                  SY N +WLQI  G                                  +W    
Sbjct: 472 ALPPAPHSYIN-EWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIM 530

Query: 297 DNHSHK------KNLFETPIL-------ARYVRILPV-AWHNRIALRLELLGC 335
           D+   K       N ++TP L        R++RI P  A H  + LR+ELLGC
Sbjct: 531 DDSKRKAKSFEGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGC 583



 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 61/189 (32%), Positives = 95/189 (50%), Gaps = 15/189 (7%)

Query: 70  CVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARL--NRAGMVNAWTPSSNDDNPW 127
           C   LG+ +G I++SQI +S+      G ++W+PE  RL  +R+G      P S   N W
Sbjct: 431 CSGMLGMVSGLISDSQITSSNQ-----GDRNWMPENIRLVTSRSGWALPPAPHSYI-NEW 484

Query: 128 IQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNK-KHKEFVGNW 186
           +Q++L     V G++ QG     +  +++ FK+ YS NG ++  I D +K K K F GN 
Sbjct: 485 LQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNN 544

Query: 187 NKNAVHVNLFETPVEAQYVRLYP-TSCHTACTLRFELLGCELN----GCANPLGLKNNSI 241
           N +   +  F   +  +++R+YP  + H    LR ELLGCE+     G   P G   +  
Sbjct: 545 NYDTPELRTFPA-LSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLVDEC 603

Query: 242 PDKQITASS 250
            D Q    S
Sbjct: 604 DDDQANCHS 612


>gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo
           sapiens]
          Length = 775

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 50/161 (31%), Positives = 90/161 (55%), Gaps = 6/161 (3%)

Query: 70  CVEPLGLENGNIANSQIAASSVR--VTFLGLQH-WVPELARLNRAGMVNAWTPSSNDDNP 126
           C   LG+E+G IA+ QI ASSV       G ++ W P+ ARL + G    W   + D+  
Sbjct: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGP--PWAAFATDEYQ 349

Query: 127 WIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVN-KKHKEFVGN 185
           W+Q++L +   +TG++T G++ +  + Y+ A+++ YS +G ++    +   ++ K F GN
Sbjct: 350 WLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGN 409

Query: 186 WNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCE 226
            + +    N F  P+ A+++R+ PT       ++ ELLGC+
Sbjct: 410 KDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGCQ 450



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 52/173 (30%), Positives = 68/173 (39%), Gaps = 58/173 (33%)

Query: 218 LRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLF---SWNPSYARLDKQGN 274
           L   L   + +GC   LG+++  I D QITASS  + W  H     SW P  ARL K G 
Sbjct: 280 LSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLE-WTDHTGQENSWKPKKARLKKPGP 338

Query: 275 FNAWVAGSYGNDQWLQI------------------------------------------- 291
              W A +    QWLQI                                           
Sbjct: 339 --PWAAFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYR 396

Query: 292 ---------FPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 335
                    F GN D H   +N F  PI+AR++R+ P  W  +IA+++ELLGC
Sbjct: 397 EPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGC 449


>gi|10835083 X-linked juvenile retinoschisis protein precursor [Homo
           sapiens]
          Length = 224

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 46/161 (28%), Positives = 77/161 (47%), Gaps = 4/161 (2%)

Query: 72  EPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQVN 131
           +PLG E+G +   QI  S+          W    ARLN  G   AW     D + W+Q++
Sbjct: 67  KPLGFESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKFQDSSQWLQID 126

Query: 132 LLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGH-EFDFIHDVNKKHKEFVGNWNKNA 190
           L     ++G++TQG  R    E++  + V Y  +    + +  D    ++ F GN ++ +
Sbjct: 127 LKEIKVISGILTQG--RCDIDEWMTKYSVQYRTDERLNWIYYKDQTGNNRVFYGNSDRTS 184

Query: 191 VHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCA 231
              NL   P+ ++++RL P   H    +R ELL C ++ CA
Sbjct: 185 TVQNLLRPPIISRFIRLIPLGWHVRIAIRMELLEC-VSKCA 224



 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 44/153 (28%), Positives = 65/153 (42%), Gaps = 51/153 (33%)

Query: 233 PLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQI- 291
           PLG ++  +   QIT S+  +  G +  SW  + ARL+ QG   AW++    + QWLQI 
Sbjct: 68  PLGFESGEVTPDQITCSNPEQYVGWYS-SWTANKARLNSQGFGCAWLSKFQDSSQWLQID 126

Query: 292 -------------------------------------------------FPGNWDNHSHK 302
                                                            F GN D  S  
Sbjct: 127 LKEIKVISGILTQGRCDIDEWMTKYSVQYRTDERLNWIYYKDQTGNNRVFYGNSDRTSTV 186

Query: 303 KNLFETPILARYVRILPVAWHNRIALRLELLGC 335
           +NL   PI++R++R++P+ WH RIA+R+ELL C
Sbjct: 187 QNLLRPPIISRFIRLIPLGWHVRIAIRMELLEC 219


>gi|27735143 discoidin, CUB and LCCL domain containing 1 [Homo
           sapiens]
          Length = 539

 Score = 72.4 bits (176), Expect = 5e-13
 Identities = 43/131 (32%), Positives = 70/131 (53%), Gaps = 3/131 (2%)

Query: 100 HWVPELARLNRAGMVNAWTPSSNDDNP--WIQVNLLRRMWVTGVVTQGASRLASHEYLKA 157
           HW P  ARL   G   A   SSN+  P  W++++L  +  +TG+ T G+++   + Y+K+
Sbjct: 284 HWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKS 343

Query: 158 FKVAYSLNGHEFDFIHD-VNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTAC 216
           F + +  N  ++      VN + K F GN N      N F  P+ A+YVR+ P + H   
Sbjct: 344 FVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRI 403

Query: 217 TLRFELLGCEL 227
            L+ EL+GC++
Sbjct: 404 ALKVELIGCQI 414



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 48/166 (28%), Positives = 67/166 (40%), Gaps = 64/166 (38%)

Query: 228 NGCANPLGLKNNSIPDKQITASSSYKTWGLH--LFSWNPSYARLDKQGNFNAWVAGSYGN 285
           NGC+  L  +    PD QI ASSS+++         W+P  ARL  QG   +W +G   N
Sbjct: 253 NGCSRSLSFE----PDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGP--SWASGDSSN 306

Query: 286 D----QWLQI-------------------------------------------------- 291
           +    +WL+I                                                  
Sbjct: 307 NHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEE 366

Query: 292 --FPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 335
             F GN +     +N F  PI+ARYVR++P  WH RIAL++EL+GC
Sbjct: 367 KVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGC 412


>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
           sapiens]
          Length = 756

 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 52/164 (31%), Positives = 79/164 (48%), Gaps = 15/164 (9%)

Query: 73  PLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVN-------AWTPSSNDDN 125
           PLGLE   I + Q+ AS+V+   LG         RLN    +N       AW    ND  
Sbjct: 138 PLGLETLKITDFQLHASTVKRYGLGAHR-----GRLNIQAGINENDFYDGAWCAGRNDLQ 192

Query: 126 PWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGN 185
            WI+V+  R    TGV+TQG + L   +++ ++KV  S + H +  + +       F GN
Sbjct: 193 QWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKN-GSGDMIFEGN 251

Query: 186 WNKNAVHVNLFETPVEAQYVRLYPTSC--HTACTLRFELLGCEL 227
             K    +N    P+ A+Y+R+ P S   + +  +R E+LGC L
Sbjct: 252 SEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPL 295



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 27/81 (33%), Positives = 41/81 (50%), Gaps = 5/81 (6%)

Query: 257 LHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQIFPGNWDNHSHKKNLFETPILARYVR 316
           L L  W  SY ++    + + WV    G+     IF GN +      N    P++ARY+R
Sbjct: 216 LWLSDWVTSY-KVMVSNDSHTWVTVKNGSGD--MIFEGNSEKEIPVLNELPVPMVARYIR 272

Query: 317 ILPVAW--HNRIALRLELLGC 335
           I P +W  +  I +R+E+LGC
Sbjct: 273 INPQSWFDNGSICMRMEILGC 293


>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
           sapiens]
          Length = 1158

 Score = 68.6 bits (166), Expect = 8e-12
 Identities = 49/168 (29%), Positives = 83/168 (49%), Gaps = 14/168 (8%)

Query: 67  ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLN-RAGMVN------AWTP 119
           + KC  P+G+E+  I ++QI ASS+    LG Q       RLN + G         AW  
Sbjct: 382 KVKC-PPIGMESHRIEDNQIRASSMLRHGLGAQR-----GRLNMQTGATEDDYYDGAWCA 435

Query: 120 SSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKH 179
             +    WI+V+  R    TGV+TQG       +++  F V +S N  +   ++    + 
Sbjct: 436 EDDARTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFS-NDSQTWVMYTNGYEE 494

Query: 180 KEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCEL 227
             F GN +K+   ++    PV A+++R+YP + + +  +R E+LGC +
Sbjct: 495 MTFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 2/58 (3%)

Query: 278 WVAGSYGNDQWLQIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 335
           WV  + G ++    F GN D  +   +    P++AR++RI P+ W+  + +RLE+LGC
Sbjct: 485 WVMYTNGYEE--MTFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGC 540


>gi|7662350 cell recognition molecule Caspr2 precursor [Homo
           sapiens]
          Length = 1331

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 18/176 (10%)

Query: 54  TCTCLKGYAGNHCETKCVEPL--GLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRA 111
           +C C + +       KC EPL  GL +   ++S   + S          + P  A++N+ 
Sbjct: 20  SCLC-RAWTAPSTSQKCDEPLVSGLPHVAFSSSSSISGS----------YSPGYAKINKR 68

Query: 112 GMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDF 171
           G    W+PS +D   W+QV+   R  ++ + TQG  R +S +++  +++ YS  G  +  
Sbjct: 69  GGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQG--RYSSSDWVTQYRMLYSDTGRNWKP 126

Query: 172 IHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCH--TACTLRFELLGC 225
            H  +     F GN N + V  +  + P+ A+YVR+ P   +      LR E+ GC
Sbjct: 127 YHQ-DGNIWAFPGNINSDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGC 181



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 59/156 (37%)

Query: 230 CANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWL 289
           C  PL    + +P    ++SSS         S++P YA+++K+G    W      + QWL
Sbjct: 35  CDEPLV---SGLPHVAFSSSSSISG------SYSPGYAKINKRGGAGGWSPSDSDHYQWL 85

Query: 290 QI------------------------------------------------FPGNWDNHSH 301
           Q+                                                FPGN ++   
Sbjct: 86  QVDFGNRKQISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGV 145

Query: 302 KKNLFETPILARYVRILPVAWH--NRIALRLELLGC 335
            ++  + PI+ARYVRI+P+ W+   RI LR+E+ GC
Sbjct: 146 VRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGC 181



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 9/51 (17%)

Query: 24  LDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLK-GYAGNHCETKCVEP 73
           +D C  N C +GG C +         + S+ CTC + GY+G  C     EP
Sbjct: 555 IDRCVPNHCEHGGKCSQ--------TWDSFKCTCDETGYSGATCHNSIYEP 597


>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
          Length = 734

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 49/172 (28%), Positives = 86/172 (50%), Gaps = 16/172 (9%)

Query: 67  ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLN-RAGMVN------AWTP 119
           ET C  PLGLE+  +++S++ ASS +   LG     P   RLN ++G+ +      AW  
Sbjct: 112 ETGC-PPLGLESLRVSDSRLEASSSQSFGLG-----PHRGRLNIQSGLEDGDLYDGAWCA 165

Query: 120 SSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHE-FDFIHDVNKK 178
              D +PW QV+       +GV+TQG + +  ++++ ++KV +S +    +   +  +  
Sbjct: 166 EEQDADPWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGM 225

Query: 179 HKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSC--HTACTLRFELLGCELN 228
              F  N +     +NL   P  A+++RL P +     A  LR E+L C ++
Sbjct: 226 DAVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVS 277



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 3/78 (3%)

Query: 260 FSWNPSYARLDKQGNFNAWVAGSYGNDQWLQIFPGNWDNHSHKKNLFETPILARYVRILP 319
           + W  SY ++    +   W      +     +FP N D  +   NL   P +AR++R+LP
Sbjct: 198 YDWVTSY-KVQFSNDSRTWWGSRNHSSGMDAVFPANSDPETPVLNLLPEPQVARFIRLLP 256

Query: 320 VAWHNRIA--LRLELLGC 335
             W    A  LR E+L C
Sbjct: 257 QTWLQGGAPCLRAEILAC 274


>gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2
           [Homo sapiens]
          Length = 1207

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 68  TKCVEPLGLENGNIANSQIAASSVRVTF-----LGLQHWVPELARLNRAGMVNAWTPSSN 122
           T+   P+G  N    +S +A++  R +F     L   H  P  +RLNR      WTP  +
Sbjct: 17  TQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHG-PGFSRLNRRDGAGGWTPLVS 75

Query: 123 DDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKE- 181
           +   W+Q++L  RM VT V TQG     S +++ ++ + +S  G  +       K+++  
Sbjct: 76  NKYQWLQIDLGERMEVTAVATQGG--YGSSDWVTSYLLMFSDGGRNW-------KQYRRE 126

Query: 182 -----FVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHT--ACTLRFELLGC 225
                F GN N ++V     + P EA+++R  P + +      +R E+ GC
Sbjct: 127 ESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 7/93 (7%)

Query: 245 QITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQIFPGNWDNHSHKKN 304
           ++TA ++   +G     W  SY  +   G  N W    Y  ++ +  FPGN +  S    
Sbjct: 90  EVTAVATQGGYGSS--DWVTSYLLMFSDGGRN-WK--QYRREESIWGFPGNTNADSVVHY 144

Query: 305 LFETPILARYVRILPVAWH--NRIALRLELLGC 335
             + P  AR++R LP+AW+   RI +R+E+ GC
Sbjct: 145 RLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177


>gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1
           [Homo sapiens]
          Length = 1288

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 68  TKCVEPLGLENGNIANSQIAASSVRVTF-----LGLQHWVPELARLNRAGMVNAWTPSSN 122
           T+   P+G  N    +S +A++  R +F     L   H  P  +RLNR      WTP  +
Sbjct: 17  TQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHG-PGFSRLNRRDGAGGWTPLVS 75

Query: 123 DDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKE- 181
           +   W+Q++L  RM VT V TQG     S +++ ++ + +S  G  +       K+++  
Sbjct: 76  NKYQWLQIDLGERMEVTAVATQGG--YGSSDWVTSYLLMFSDGGRNW-------KQYRRE 126

Query: 182 -----FVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHT--ACTLRFELLGC 225
                F GN N ++V     + P EA+++R  P + +      +R E+ GC
Sbjct: 127 ESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 7/93 (7%)

Query: 245 QITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQIFPGNWDNHSHKKN 304
           ++TA ++   +G     W  SY  +   G  N W    Y  ++ +  FPGN +  S    
Sbjct: 90  EVTAVATQGGYGSS--DWVTSYLLMFSDGGRN-WK--QYRREESIWGFPGNTNADSVVHY 144

Query: 305 LFETPILARYVRILPVAWH--NRIALRLELLGC 335
             + P  AR++R LP+AW+   RI +R+E+ GC
Sbjct: 145 RLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177


>gi|239743729 PREDICTED: similar to contactin associated
           protein-like 3B [Homo sapiens]
          Length = 380

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 46/171 (26%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 68  TKCVEPLGLENGNIANSQIAASSVRVTF-----LGLQHWVPELARLNRAGMVNAWTPSSN 122
           T+   P+G  N    ++ +A++  R +F     L   H  P  +RLNR      WTP  +
Sbjct: 17  TQTWSPVGAGNPPDCDAPLASALPRSSFSSSSELSSSHG-PGFSRLNRRDGAGGWTPLVS 75

Query: 123 DDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKE- 181
           +   W+Q++L  RM VT V TQG     S +++ ++ + +S  G  +       K+++  
Sbjct: 76  NKYQWLQIDLGERMEVTAVATQGG--YGSSDWVTSYLLMFSDGGRNW-------KQYRRE 126

Query: 182 -----FVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHT--ACTLRFELLGC 225
                F GN N ++V     + P EA+++R  P + +      +R E+ GC
Sbjct: 127 ESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 7/93 (7%)

Query: 245 QITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQIFPGNWDNHSHKKN 304
           ++TA ++   +G     W  SY  +   G  N W    Y  ++ +  FPGN +  S    
Sbjct: 90  EVTAVATQGGYGSS--DWVTSYLLMFSDGGRN-WK--QYRREESIWGFPGNTNADSVVHY 144

Query: 305 LFETPILARYVRILPVAWH--NRIALRLELLGC 335
             + P  AR++R LP+AW+   RI +R+E+ GC
Sbjct: 145 RLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177


>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
          Length = 1288

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 46/171 (26%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 68  TKCVEPLGLENGNIANSQIAASSVRVTF-----LGLQHWVPELARLNRAGMVNAWTPSSN 122
           T+   P+G  N    ++ +A++  R +F     L   H  P  +RLNR      WTP  +
Sbjct: 17  TQTWSPVGAGNPPDCDAPLASALPRSSFSSSSELSSSHG-PGFSRLNRRDGAGGWTPLVS 75

Query: 123 DDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKE- 181
           +   W+Q++L  RM VT V TQG     S +++ ++ + +S  G  +       K+++  
Sbjct: 76  NKYQWLQIDLGERMEVTAVATQGG--YGSSDWVTSYLLMFSDGGRNW-------KQYRRE 126

Query: 182 -----FVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHT--ACTLRFELLGC 225
                F GN N ++V     + P EA+++R  P + +      +R E+ GC
Sbjct: 127 ESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 7/93 (7%)

Query: 245 QITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQIFPGNWDNHSHKKN 304
           ++TA ++   +G     W  SY  +   G  N W    Y  ++ +  FPGN +  S    
Sbjct: 90  EVTAVATQGGYGSS--DWVTSYLLMFSDGGRN-WK--QYRREESIWGFPGNTNADSVVHY 144

Query: 305 LFETPILARYVRILPVAWH--NRIALRLELLGC 335
             + P  AR++R LP+AW+   RI +R+E+ GC
Sbjct: 145 RLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177


>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo
           sapiens]
          Length = 1235

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 35/131 (26%), Positives = 64/131 (48%), Gaps = 17/131 (12%)

Query: 103 PELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAY 162
           P  ARLNR      W+P  ++   W+Q++L  RM VT V TQG     S  ++ ++ + +
Sbjct: 31  PGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGG--YGSSNWVTSYLLMF 88

Query: 163 SLNGHEFDFIHDVNKKHKE------FVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHT-- 214
           S +G  +       K++++      F GN N ++V     +  ++A+++R  P   +   
Sbjct: 89  SDSGWNW-------KQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKG 141

Query: 215 ACTLRFELLGC 225
              +R E+ GC
Sbjct: 142 RIGMRIEVFGC 152



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 7/93 (7%)

Query: 245 QITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQIFPGNWDNHSHKKN 304
           ++TA ++   +G    +W  SY  +     +N W    Y  +  +  F GN +  S    
Sbjct: 65  EVTAVATQGGYGSS--NWVTSYLLMFSDSGWN-WK--QYRQEDSIWGFSGNANADSVVYY 119

Query: 305 LFETPILARYVRILPVAWH--NRIALRLELLGC 335
             +  I AR++R +P+ W+   RI +R+E+ GC
Sbjct: 120 RLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGC 152


>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo
           sapiens]
          Length = 1308

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 35/131 (26%), Positives = 64/131 (48%), Gaps = 17/131 (12%)

Query: 103 PELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAY 162
           P  ARLNR      W+P  ++   W+Q++L  RM VT V TQG     S  ++ ++ + +
Sbjct: 56  PGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGG--YGSSNWVTSYLLMF 113

Query: 163 SLNGHEFDFIHDVNKKHKE------FVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHT-- 214
           S +G  +       K++++      F GN N ++V     +  ++A+++R  P   +   
Sbjct: 114 SDSGWNW-------KQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKG 166

Query: 215 ACTLRFELLGC 225
              +R E+ GC
Sbjct: 167 RIGMRIEVFGC 177



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 7/93 (7%)

Query: 245 QITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQIFPGNWDNHSHKKN 304
           ++TA ++   +G    +W  SY  +     +N W    Y  +  +  F GN +  S    
Sbjct: 90  EVTAVATQGGYGSS--NWVTSYLLMFSDSGWN-WK--QYRQEDSIWGFSGNANADSVVYY 144

Query: 305 LFETPILARYVRILPVAWH--NRIALRLELLGC 335
             +  I AR++R +P+ W+   RI +R+E+ GC
Sbjct: 145 RLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGC 177


>gi|62420886 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 47/164 (28%), Positives = 75/164 (45%), Gaps = 16/164 (9%)

Query: 70  CVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPS----SNDDN 125
           C  PLG+  G I +  I ASS        +    +  RL+      AW P      +D  
Sbjct: 30  CRYPLGMSGGQIPDEDITASSQ-----WSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLK 84

Query: 126 PWIQVNLLRRMWVTGVVTQGASRLASH--EYLKAFKVAYSLNGHEFDFIHDVNKKHKEFV 183
            ++Q++L    ++T V TQG      H  E+   +K+ YS +G  +  I   N+  K+ +
Sbjct: 85  EFLQIDLHTLHFITLVGTQGR-HAGGHGIEFAPMYKINYSRDGTRW--ISWRNRHGKQVL 141

Query: 184 -GNWNKNAVHVNLFETPVEAQYVRLYPTSCHTA-CTLRFELLGC 225
            GN N   + +   E P+ A++VR  P + H+    +R EL GC
Sbjct: 142 DGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGC 185



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 41/162 (25%), Positives = 59/162 (36%), Gaps = 62/162 (38%)

Query: 230 CANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWV---------- 279
           C  PLG+    IPD+ ITASS +        S    Y RLD +    AW           
Sbjct: 30  CRYPLGMSGGQIPDEDITASSQWSE------STAAKYGRLDSEEGDGAWCPEIPVEPDDL 83

Query: 280 -----------------------AGSYGND--------------QWL--------QIFPG 294
                                  AG +G +              +W+        Q+  G
Sbjct: 84  KEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDG 143

Query: 295 NWDNHSHKKNLFETPILARYVRILPVAWHN-RIALRLELLGC 335
           N + +       E PI+AR+VR +PV  H+  + +R+EL GC
Sbjct: 144 NSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGC 185


>gi|62420884 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 47/164 (28%), Positives = 75/164 (45%), Gaps = 16/164 (9%)

Query: 70  CVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPS----SNDDN 125
           C  PLG+  G I +  I ASS        +    +  RL+      AW P      +D  
Sbjct: 30  CRYPLGMSGGQIPDEDITASSQ-----WSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLK 84

Query: 126 PWIQVNLLRRMWVTGVVTQGASRLASH--EYLKAFKVAYSLNGHEFDFIHDVNKKHKEFV 183
            ++Q++L    ++T V TQG      H  E+   +K+ YS +G  +  I   N+  K+ +
Sbjct: 85  EFLQIDLHTLHFITLVGTQGR-HAGGHGIEFAPMYKINYSRDGTRW--ISWRNRHGKQVL 141

Query: 184 -GNWNKNAVHVNLFETPVEAQYVRLYPTSCHTA-CTLRFELLGC 225
            GN N   + +   E P+ A++VR  P + H+    +R EL GC
Sbjct: 142 DGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGC 185



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 41/162 (25%), Positives = 59/162 (36%), Gaps = 62/162 (38%)

Query: 230 CANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWV---------- 279
           C  PLG+    IPD+ ITASS +        S    Y RLD +    AW           
Sbjct: 30  CRYPLGMSGGQIPDEDITASSQWSE------STAAKYGRLDSEEGDGAWCPEIPVEPDDL 83

Query: 280 -----------------------AGSYGND--------------QWL--------QIFPG 294
                                  AG +G +              +W+        Q+  G
Sbjct: 84  KEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDG 143

Query: 295 NWDNHSHKKNLFETPILARYVRILPVAWHN-RIALRLELLGC 335
           N + +       E PI+AR+VR +PV  H+  + +R+EL GC
Sbjct: 144 NSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGC 185


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,741,818
Number of Sequences: 37866
Number of extensions: 613400
Number of successful extensions: 2535
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 94
Number of HSP's that attempted gapping in prelim test: 1518
Number of HSP's gapped (non-prelim): 782
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.