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Search of human proteins with 16751923
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
netrin domain containing 1 precursor [Homo sapiens]
(548 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n... 1166 0.0
gi|28212222 WFIKKN2 protein [Homo sapiens] 634 0.0
gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo sap... 85 2e-16
gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens] 72 1e-12
gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo sapi... 69 8e-12
gi|5454114 tissue factor pathway inhibitor isoform a precursor [... 69 1e-11
gi|73760409 tissue factor pathway inhibitor isoform b precursor ... 69 1e-11
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 64 3e-10
gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor [... 64 5e-10
gi|22902128 PTK7 protein tyrosine kinase 7 isoform c precursor [... 64 5e-10
gi|22902126 PTK7 protein tyrosine kinase 7 isoform b precursor [... 64 5e-10
gi|144226847 obscurin-like 1 [Homo sapiens] 63 6e-10
gi|224994173 roundabout 1 isoform d [Homo sapiens] 63 8e-10
gi|224994171 roundabout 1 isoform c [Homo sapiens] 63 8e-10
gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP... 63 8e-10
gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP... 63 8e-10
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 63 8e-10
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ... 63 8e-10
gi|145309328 papilin [Homo sapiens] 63 8e-10
gi|109150416 peroxidasin [Homo sapiens] 62 1e-09
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 61 3e-09
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 61 3e-09
gi|118572606 hemicentin 1 [Homo sapiens] 60 5e-09
gi|153946389 WAP four-disulfide core domain 8 precursor [Homo sa... 60 5e-09
gi|153946387 WAP four-disulfide core domain 8 precursor [Homo sa... 60 5e-09
gi|110349721 titin isoform novex-3 [Homo sapiens] 60 7e-09
gi|19743806 roundabout 1 isoform b [Homo sapiens] 60 7e-09
gi|110349719 titin isoform N2-A [Homo sapiens] 60 7e-09
gi|110349717 titin isoform novex-2 [Homo sapiens] 60 7e-09
gi|110349713 titin isoform novex-1 [Homo sapiens] 60 7e-09
>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
netrin domain containing 1 precursor [Homo sapiens]
Length = 548
Score = 1166 bits (3016), Expect = 0.0
Identities = 548/548 (100%), Positives = 548/548 (100%)
Query: 1 MPALRPLLPLLLLLRLTSGAGLLPGLGSHPGVCPNQLSPNLWVDAQSTCERECSRDQDCA 60
MPALRPLLPLLLLLRLTSGAGLLPGLGSHPGVCPNQLSPNLWVDAQSTCERECSRDQDCA
Sbjct: 1 MPALRPLLPLLLLLRLTSGAGLLPGLGSHPGVCPNQLSPNLWVDAQSTCERECSRDQDCA 60
Query: 61 AAEKCCINVCGLHSCVAARFPGSPAAPTTAASCEGFVCPQQGSDCDIWDGQPVCRCRDRC 120
AAEKCCINVCGLHSCVAARFPGSPAAPTTAASCEGFVCPQQGSDCDIWDGQPVCRCRDRC
Sbjct: 61 AAEKCCINVCGLHSCVAARFPGSPAAPTTAASCEGFVCPQQGSDCDIWDGQPVCRCRDRC 120
Query: 121 EKEPSFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPG 180
EKEPSFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPG
Sbjct: 121 EKEPSFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPG 180
Query: 181 AAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNV 240
AAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNV
Sbjct: 181 AAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNV 240
Query: 241 VVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECL 300
VVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECL
Sbjct: 241 VVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECL 300
Query: 301 PDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDACV 360
PDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDACV
Sbjct: 301 PDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDACV 360
Query: 361 LPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTPPCRAC 420
LPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTPPCRAC
Sbjct: 361 LPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTPPCRAC 420
Query: 421 RLRSKLALSLCRSDFAIVGRLTEVLEEPEAAGGIARVALEDVLKDDKMGLKFLGTKYLEV 480
RLRSKLALSLCRSDFAIVGRLTEVLEEPEAAGGIARVALEDVLKDDKMGLKFLGTKYLEV
Sbjct: 421 RLRSKLALSLCRSDFAIVGRLTEVLEEPEAAGGIARVALEDVLKDDKMGLKFLGTKYLEV 480
Query: 481 TLSGMDWACPCPNMTAGDGPLVIMGEVRDGVAVLDAGSYVRAASEKRVKKILELLEKQAC 540
TLSGMDWACPCPNMTAGDGPLVIMGEVRDGVAVLDAGSYVRAASEKRVKKILELLEKQAC
Sbjct: 481 TLSGMDWACPCPNMTAGDGPLVIMGEVRDGVAVLDAGSYVRAASEKRVKKILELLEKQAC 540
Query: 541 ELLNRFQD 548
ELLNRFQD
Sbjct: 541 ELLNRFQD 548
>gi|28212222 WFIKKN2 protein [Homo sapiens]
Length = 576
Score = 634 bits (1634), Expect = 0.0
Identities = 311/560 (55%), Positives = 388/560 (69%), Gaps = 26/560 (4%)
Query: 7 LLPLLLLLRLTSGAGLLPGLG-SHPGVCPNQLSPNLWVDAQSTCERECSRDQDCAAAEKC 65
LL LLLLL + + LP + SH G+CPN ++PNLWVDAQSTC REC DQ+C EKC
Sbjct: 19 LLLLLLLLGVPPRSLALPPIRYSHAGICPNDMNPNLWVDAQSTCRRECETDQECETYEKC 78
Query: 66 CINVCGLHSCVAARFPG-----SPAAPTTAASCEGFVCPQQGSDCDIWDGQPVCRCRDRC 120
C NVCG SCVAAR+ P A+C+ F+C QQGS+CDIWDGQPVC+C+DRC
Sbjct: 79 CPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQGSECDIWDGQPVCKCKDRC 138
Query: 121 EKEPSFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPG 180
EKEPSFTCASDGLTYYNRCYMDAEAC +G+ L +V C++ +WP +SP PPETT PT
Sbjct: 139 EKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFTWPNTSPPPPETTMHPTTA 198
Query: 181 AAPVP------PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPD 234
+ P PAL ++P Q+V +G T S CDV GRP P +TWEKQ REN++MRP+
Sbjct: 199 SPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPN 258
Query: 235 QMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIP 294
+ GNVVVT+I QLV+YNA+ +DAG+YTCTARN AG+LRADFPLSVV+ A + S P
Sbjct: 259 HVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVVRGHQAAATSESSP 318
Query: 295 -----APAECL--PDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEAC 347
AECL PD + C WH+D Q C+TF C FETYEAC
Sbjct: 319 NGTAFPAAECLKPPDSEDC----GEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEAC 374
Query: 348 QQACARGPGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCED 407
AC GP AC LPA+QGPC+ + PRWAY+ QC FVYGGCEGNGNNF SRE+CE+
Sbjct: 375 MLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEE 434
Query: 408 ACPVPR-TPPCRACRLRSKLALSLCRSDFAIVGRLTEVLEEPEAAGGIARVALEDVLKDD 466
+CP PR CRAC+ R KL S CRSDF I+GR++E+ EEP++ G A V +++VLKD+
Sbjct: 435 SCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSELTEEPDS--GRALVTVDEVLKDE 492
Query: 467 KMGLKFLGTKYLEVTLSGMDWACPCPNMTAGDGPLVIMGEVRDGVAVLDAGSYVRAASEK 526
KMGLKFLG + LEVTL +DWACPCPN+T + PL+IMGEV G+A+L S+V A+S +
Sbjct: 493 KMGLKFLGQEPLEVTLLHVDWACPCPNVTVSEMPLIIMGEVDGGMAMLRPDSFVGASSAR 552
Query: 527 RVKKILELLEKQACELLNRF 546
RV+K+ E++ K+ C++L F
Sbjct: 553 RVRKLREVMHKKTCDVLKEF 572
>gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo
sapiens]
Length = 352
Score = 84.7 bits (208), Expect = 2e-16
Identities = 43/107 (40%), Positives = 55/107 (51%), Gaps = 6/107 (5%)
Query: 306 CTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDACVLPAVQ 365
C G TS + Y+ C TF GC G F T + C Q C AC LP V+
Sbjct: 240 CMGMTSRYF----YNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVA--ACNLPIVR 293
Query: 366 GPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVP 412
GPCR + WA+ + +C F YGGC+GNGN F+S + C + C VP
Sbjct: 294 GPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCGVP 340
Score = 56.6 bits (135), Expect = 6e-08
Identities = 29/71 (40%), Positives = 35/71 (49%), Gaps = 9/71 (12%)
Query: 357 DACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC------- 409
D+C L GPC G R+ Y+ C F YGGC GNGNNF + + C C
Sbjct: 229 DSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAACN 288
Query: 410 -PVPRTPPCRA 419
P+ R PCRA
Sbjct: 289 LPIVR-GPCRA 298
>gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens]
Length = 235
Score = 72.0 bits (175), Expect = 1e-12
Identities = 41/121 (33%), Positives = 61/121 (50%), Gaps = 3/121 (2%)
Query: 357 DACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC-PVPRTP 415
+ C+LP GPCR R+ Y Q C F+YGGCEGN NNF++ E+C+DAC + + P
Sbjct: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVP 93
Query: 416 PCRACRLRSKLALSLCRSDFAIVGRLTEVLEEPEAAGGIARVALEDVLKDDKMGLKFLGT 475
+ CRL+ + S L+ + E +GG R +E+ D+ + F
Sbjct: 94 --KVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAP 151
Query: 476 K 476
K
Sbjct: 152 K 152
Score = 56.2 bits (134), Expect = 7e-08
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 5/113 (4%)
Query: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACAR---GPGDACVLPAV 364
GP L+ ++YD C F GC+G A F T+EAC AC R P + +V
Sbjct: 43 GPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKVCRLQVSV 102
Query: 365 QGPCRGWEPRWAYSPLLQQCHPFVYGGCEGN--GNNFHSRESCEDACPVPRTP 415
C G ++ ++ C F GGC N N F +C C + P
Sbjct: 103 DDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIP 155
Score = 52.4 bits (124), Expect = 1e-06
Identities = 30/87 (34%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
Query: 326 CMTFPARGC--DGAARGFETYEACQQACA-RGPGDACVLPAVQGPCRGWEPRWAYSPLLQ 382
C F + GC + F C CA + C P +G C R+ ++P +
Sbjct: 122 CEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYR 181
Query: 383 QCHPFVYGGCEGNGNNFHSRESCEDAC 409
C F Y GC GN NNF SRE C+ AC
Sbjct: 182 TCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 33.5 bits (75), Expect = 0.52
Identities = 14/46 (30%), Positives = 25/46 (54%)
Query: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACAR 353
G S ++ ++++P+ C F GC G F + E C++ACA+
Sbjct: 165 GLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
>gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo
sapiens]
Length = 252
Score = 69.3 bits (168), Expect = 8e-12
Identities = 39/130 (30%), Positives = 50/130 (38%), Gaps = 37/130 (28%)
Query: 317 WHYDPQRGGCMTFPARGCDGAARGFETYEACQQACA-------------RGPGDA----- 358
W Y+ G C F GCDG + + T E C + CA R D+
Sbjct: 54 WWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSA 113
Query: 359 -------------------CVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNF 399
C AV GPCR PRW + C+ F+YGGC GN N++
Sbjct: 114 PRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSY 173
Query: 400 HSRESCEDAC 409
S E+C C
Sbjct: 174 RSEEACMLRC 183
Score = 57.8 bits (138), Expect = 3e-08
Identities = 24/53 (45%), Positives = 31/53 (58%)
Query: 357 DACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
D C++ V G CR PRW Y+ C FVYGGC+GN NN+ ++E C C
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88
Score = 39.7 bits (91), Expect = 0.007
Identities = 17/49 (34%), Positives = 22/49 (44%)
Query: 305 ACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACAR 353
A TGP W++D +R C F GC G + + EAC C R
Sbjct: 137 AVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFR 185
>gi|5454114 tissue factor pathway inhibitor isoform a precursor
[Homo sapiens]
Length = 304
Score = 68.9 bits (167), Expect = 1e-11
Identities = 39/131 (29%), Positives = 53/131 (40%), Gaps = 34/131 (25%)
Query: 313 HLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDA-------------- 358
++ + Y+ Q C F GC G FET E C+ C GP
Sbjct: 137 YITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQVDNYGTQLNAVNN 196
Query: 359 --------------------CVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNN 398
C+ PA +G CR E R+ Y+ ++ +C PF Y GC GN NN
Sbjct: 197 SLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENN 256
Query: 399 FHSRESCEDAC 409
F S++ C AC
Sbjct: 257 FTSKQECLRAC 267
Score = 68.6 bits (166), Expect = 1e-11
Identities = 35/97 (36%), Positives = 46/97 (47%), Gaps = 13/97 (13%)
Query: 326 CMTFPARGCDGAARGFETYEACQQACARGPG-------------DACVLPAVQGPCRGWE 372
C F GC+G FE+ E C++ C R D C L G CRG+
Sbjct: 79 CEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYI 138
Query: 373 PRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
R+ Y+ +QC F YGGC GN NNF + E C++ C
Sbjct: 139 TRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
Score = 55.8 bits (133), Expect = 1e-07
Identities = 22/51 (43%), Positives = 29/51 (56%)
Query: 359 CVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
C A GPC+ R+ ++ +QC F+YGGCEGN N F S E C+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
Score = 30.8 bits (68), Expect = 3.3
Identities = 12/38 (31%), Positives = 19/38 (50%)
Query: 317 WHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARG 354
++Y+ G C F GC G F + + C +AC +G
Sbjct: 233 FYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKG 270
>gi|73760409 tissue factor pathway inhibitor isoform b precursor
[Homo sapiens]
Length = 251
Score = 68.6 bits (166), Expect = 1e-11
Identities = 35/97 (36%), Positives = 46/97 (47%), Gaps = 13/97 (13%)
Query: 326 CMTFPARGCDGAARGFETYEACQQACARGPG-------------DACVLPAVQGPCRGWE 372
C F GC+G FE+ E C++ C R D C L G CRG+
Sbjct: 79 CEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYI 138
Query: 373 PRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
R+ Y+ +QC F YGGC GN NNF + E C++ C
Sbjct: 139 TRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
Score = 55.8 bits (133), Expect = 1e-07
Identities = 22/51 (43%), Positives = 29/51 (56%)
Query: 359 CVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
C A GPC+ R+ ++ +QC F+YGGCEGN N F S E C+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
Score = 34.3 bits (77), Expect = 0.30
Identities = 15/43 (34%), Positives = 20/43 (46%)
Query: 313 HLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGP 355
++ + Y+ Q C F GC G FET E C+ C GP
Sbjct: 137 YITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGP 179
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 64.3 bits (155), Expect = 3e-10
Identities = 28/57 (49%), Positives = 34/57 (59%), Gaps = 3/57 (5%)
Query: 357 DACVLPAVQGPCRGWEPRW---AYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACP 410
D C LP +G C + RW A + + CHPFVYGGC GN N F +RE+CE CP
Sbjct: 2874 DPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRCP 2930
Score = 30.4 bits (67), Expect = 4.4
Identities = 15/47 (31%), Positives = 22/47 (46%), Gaps = 3/47 (6%)
Query: 308 GPTSPHLVLWHYDPQRGG---CMTFPARGCDGAARGFETYEACQQAC 351
G + + + W++ G C F GC G A F T EAC++ C
Sbjct: 2883 GSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2929
>gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor
[Homo sapiens]
Length = 1070
Score = 63.5 bits (153), Expect = 5e-10
Identities = 34/125 (27%), Positives = 57/125 (45%), Gaps = 6/125 (4%)
Query: 192 PSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLY 251
P V G TA L C+ G P P + W+ + I+ P ++ + + G LV++
Sbjct: 598 PERTTVYQGHTALLQCEAQGDPKPLIQWKGKDR-----ILDPTKLGPRMHIFQNGSLVIH 652
Query: 252 NARPEDAGLYTCTARNAAGLLRADFPLSVVQRE-PARDAAPSIPAPAECLPDVQACTGPT 310
+ PED+G YTC A N+ + + PL VV + P P P P + + + G
Sbjct: 653 DVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAA 712
Query: 311 SPHLV 315
+++
Sbjct: 713 VAYII 717
Score = 43.5 bits (101), Expect = 5e-04
Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 193 SPQAVQVGG--TASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVL 250
+PQ V V A HC S +PPP++ W + RP + V + G L+L
Sbjct: 230 APQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHL-RRATVFANGSLLL 288
Query: 251 YNARPEDAGLYTCTARNAAG---LLRADFPLSVVQREP 285
RP +AG+Y C + G +L A L+ ++ P
Sbjct: 289 TQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Score = 39.3 bits (90), Expect = 0.009
Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 9/105 (8%)
Query: 186 PALYSSPSPQA-VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
P + P+ +A +Q +L C + G P P W + D + V +
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLS------DGQSNHTVSSK 181
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG--LLRADFPLSVVQREPAR 287
L L A PE +GLY+C A +A G +F LS+ AR
Sbjct: 182 ERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFAR 226
Score = 38.1 bits (87), Expect = 0.021
Identities = 39/132 (29%), Positives = 53/132 (40%), Gaps = 22/132 (16%)
Query: 194 PQAVQVGGTASLHC-DVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYN 252
P+ G + C G P P+V WE H L +G V +LVL N
Sbjct: 330 PRVFTAGSEERVTCLPPKGLPEPSVWWE---HAGVRL-----PTHGRVYQKG-HELVLAN 380
Query: 253 ARPEDAGLYTCTARNAAGLLRADFPLSV------VQREPARDAAPSIPAPAECLPDVQAC 306
DAG+YTC A N AG R D ++V +++ P +CL QA
Sbjct: 381 IAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCL--TQAT 438
Query: 307 TGPTSPHLVLWH 318
PT V+W+
Sbjct: 439 PKPT----VVWY 446
Score = 35.8 bits (81), Expect = 0.10
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 12/91 (13%)
Query: 192 PSPQ-AVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVL 250
P PQ ++ A++ C +GR P + WE+ V + G L
Sbjct: 508 PQPQQCMEFDKEATVPCSATGREKPTIKWERAD----------GSSLPEWVTDNAGTLHF 557
Query: 251 YNARPEDAGLYTCTARNA-AGLLRADFPLSV 280
+DAG YTC A N G +RA L+V
Sbjct: 558 ARVTRDDAGNYTCIASNGPQGQIRAHVQLTV 588
Score = 33.5 bits (75), Expect = 0.52
Identities = 29/126 (23%), Positives = 46/126 (36%), Gaps = 12/126 (9%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P+ P ++ G L C P P V W R +++ D + V
Sbjct: 412 PSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVW-----YRNQMLISEDSRF---EVFKN 463
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQA 305
G L + + D Y C + AG + A + V+ E + P P P +C+ +
Sbjct: 464 GTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVL--EKLKFTPP--PQPQQCMEFDKE 519
Query: 306 CTGPTS 311
T P S
Sbjct: 520 ATVPCS 525
>gi|22902128 PTK7 protein tyrosine kinase 7 isoform c precursor
[Homo sapiens]
Length = 940
Score = 63.5 bits (153), Expect = 5e-10
Identities = 34/125 (27%), Positives = 57/125 (45%), Gaps = 6/125 (4%)
Query: 192 PSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLY 251
P V G TA L C+ G P P + W+ + I+ P ++ + + G LV++
Sbjct: 468 PERTTVYQGHTALLQCEAQGDPKPLIQWKGKDR-----ILDPTKLGPRMHIFQNGSLVIH 522
Query: 252 NARPEDAGLYTCTARNAAGLLRADFPLSVVQRE-PARDAAPSIPAPAECLPDVQACTGPT 310
+ PED+G YTC A N+ + + PL VV + P P P P + + + G
Sbjct: 523 DVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAA 582
Query: 311 SPHLV 315
+++
Sbjct: 583 VAYII 587
Score = 43.5 bits (101), Expect = 5e-04
Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 193 SPQAVQVGG--TASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVL 250
+PQ V V A HC S +PPP++ W + RP + V + G L+L
Sbjct: 230 APQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHL-RRATVFANGSLLL 288
Query: 251 YNARPEDAGLYTCTARNAAG---LLRADFPLSVVQREP 285
RP +AG+Y C + G +L A L+ ++ P
Sbjct: 289 TQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Score = 39.3 bits (90), Expect = 0.009
Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 9/105 (8%)
Query: 186 PALYSSPSPQA-VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
P + P+ +A +Q +L C + G P P W + D + V +
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLS------DGQSNHTVSSK 181
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG--LLRADFPLSVVQREPAR 287
L L A PE +GLY+C A +A G +F LS+ AR
Sbjct: 182 ERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFAR 226
Score = 37.7 bits (86), Expect = 0.027
Identities = 30/88 (34%), Positives = 38/88 (43%), Gaps = 10/88 (11%)
Query: 194 PQAVQVGGTASLHC-DVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYN 252
P+ G + C G P P+V WE H L +G V +LVL N
Sbjct: 330 PRVFTAGSEERVTCLPPKGLPEPSVWWE---HAGVRL-----PTHGRVYQKG-HELVLAN 380
Query: 253 ARPEDAGLYTCTARNAAGLLRADFPLSV 280
DAG+YTC A N AG R D ++V
Sbjct: 381 IAESDAGVYTCHAANLAGQRRQDVNITV 408
>gi|22902126 PTK7 protein tyrosine kinase 7 isoform b precursor
[Homo sapiens]
Length = 1030
Score = 63.5 bits (153), Expect = 5e-10
Identities = 34/125 (27%), Positives = 57/125 (45%), Gaps = 6/125 (4%)
Query: 192 PSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLY 251
P V G TA L C+ G P P + W+ + I+ P ++ + + G LV++
Sbjct: 558 PERTTVYQGHTALLQCEAQGDPKPLIQWKGKDR-----ILDPTKLGPRMHIFQNGSLVIH 612
Query: 252 NARPEDAGLYTCTARNAAGLLRADFPLSVVQRE-PARDAAPSIPAPAECLPDVQACTGPT 310
+ PED+G YTC A N+ + + PL VV + P P P P + + + G
Sbjct: 613 DVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAA 672
Query: 311 SPHLV 315
+++
Sbjct: 673 VAYII 677
Score = 43.5 bits (101), Expect = 5e-04
Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 193 SPQAVQVGG--TASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVL 250
+PQ V V A HC S +PPP++ W + RP + V + G L+L
Sbjct: 230 APQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHL-RRATVFANGSLLL 288
Query: 251 YNARPEDAGLYTCTARNAAG---LLRADFPLSVVQREP 285
RP +AG+Y C + G +L A L+ ++ P
Sbjct: 289 TQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Score = 39.3 bits (90), Expect = 0.009
Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 9/105 (8%)
Query: 186 PALYSSPSPQA-VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
P + P+ +A +Q +L C + G P P W + D + V +
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLS------DGQSNHTVSSK 181
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG--LLRADFPLSVVQREPAR 287
L L A PE +GLY+C A +A G +F LS+ AR
Sbjct: 182 ERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFAR 226
Score = 38.1 bits (87), Expect = 0.021
Identities = 39/132 (29%), Positives = 53/132 (40%), Gaps = 22/132 (16%)
Query: 194 PQAVQVGGTASLHC-DVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYN 252
P+ G + C G P P+V WE H L +G V +LVL N
Sbjct: 330 PRVFTAGSEERVTCLPPKGLPEPSVWWE---HAGVRL-----PTHGRVYQKG-HELVLAN 380
Query: 253 ARPEDAGLYTCTARNAAGLLRADFPLSV------VQREPARDAAPSIPAPAECLPDVQAC 306
DAG+YTC A N AG R D ++V +++ P +CL QA
Sbjct: 381 IAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCL--TQAT 438
Query: 307 TGPTSPHLVLWH 318
PT V+W+
Sbjct: 439 PKPT----VVWY 446
>gi|144226847 obscurin-like 1 [Homo sapiens]
Length = 1896
Score = 63.2 bits (152), Expect = 6e-10
Identities = 48/135 (35%), Positives = 59/135 (43%), Gaps = 17/135 (12%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQ---RENLIMRPDQMYGNVV 241
PP P P V G A L C V G PPP V WEK Q E L D ++
Sbjct: 11 PPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLL 70
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARD-----AAPSIPAP 296
+T+ A P DAG+Y C ARNAAG A ++V++ PA D A +P+P
Sbjct: 71 LTA--------ALPTDAGVYVCRARNAAGEAYAAAAVTVLE-PPASDPELQPAERPLPSP 121
Query: 297 AECLPDVQACTGPTS 311
TGP S
Sbjct: 122 GSGEGAPVFLTGPRS 136
Score = 51.6 bits (122), Expect = 2e-06
Identities = 44/154 (28%), Positives = 61/154 (39%), Gaps = 14/154 (9%)
Query: 160 VLSWPPSSPG-PPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVT 218
VL P S P P P+PG+ P + P Q V G L C G P P +
Sbjct: 101 VLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLY 160
Query: 219 WEK------QSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLL 272
WEK + + ++P + + L + AR D+G+Y C ARNA G
Sbjct: 161 WEKDGMALDEVWDSSHFALQPGRAEDGPGASL--ALRILAARLPDSGVYVCHARNAHGHA 218
Query: 273 RADFPLSVVQREPARDAAPS-----IPAPAECLP 301
+A L V Q + A P + P +C P
Sbjct: 219 QAGALLQVHQPPESPPADPDEAPAPVVEPLKCAP 252
Score = 48.5 bits (114), Expect = 2e-05
Identities = 39/111 (35%), Positives = 49/111 (44%), Gaps = 17/111 (15%)
Query: 164 PPSSPGPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQS 223
PP SP A P APV L +P V G A C V G+P P + W +
Sbjct: 229 PPESP-----PADPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEG 283
Query: 224 H----QRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
R L+ R D+ G V+ VLY + +D GLY C ARN+AG
Sbjct: 284 RPLLPDRRRLMYR-DRDGGFVL------KVLY-CQAKDRGLYVCAARNSAG 326
Score = 41.6 bits (96), Expect = 0.002
Identities = 44/146 (30%), Positives = 58/146 (39%), Gaps = 21/146 (14%)
Query: 187 ALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIG 246
AL ++PSP V G L C++S P V W RP Q + + + G
Sbjct: 1175 ALETTPSPLCVAPGEPVVLSCELSRAGAPVV-WSHNG--------RPVQEGEGLELHAEG 1225
Query: 247 Q---LVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSI------PAPA 297
L + A P AGLYTC + A G F + V + P R AP P
Sbjct: 1226 PRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAE-PPVRVVAPEAAQTRVRSTPG 1284
Query: 298 ECLPDVQACTGPTSPHLVLWHYDPQR 323
L V +GP P V W+ D +R
Sbjct: 1285 GDLELVVHLSGPGGP--VRWYKDGER 1308
Score = 33.9 bits (76), Expect = 0.40
Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 11/101 (10%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
VP + P V G TA+ C++S + VTWEK + + P +
Sbjct: 1627 VPVTIVRGPHDLEVTEGDTATFECELS-QALADVTWEKDGNA-----LTPSPRLRLQALG 1680
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQRE 284
+ L L P DAG Y+C A G RA P+ + RE
Sbjct: 1681 TRRLLQLRRCGPSDAGTYSC----AVGTARAG-PVRLTVRE 1716
Score = 32.0 bits (71), Expect = 1.5
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 7/76 (9%)
Query: 248 LVLYNARPEDAGLYTCTARNAA---GLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQ 304
L L +A+PEDAG Y C R+ A ++ A+ P+ + E +P AP E P V
Sbjct: 1138 LTLPHAQPEDAGEYVCETRHEAITFNVILAEPPVQFLALETT--PSPLCVAPGE--PVVL 1193
Query: 305 ACTGPTSPHLVLWHYD 320
+C + V+W ++
Sbjct: 1194 SCELSRAGAPVVWSHN 1209
Score = 31.2 bits (69), Expect = 2.6
Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 7/97 (7%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN 228
GP ++ A A P+ + P + V VG A L VS R V W RE
Sbjct: 1793 GPAQSLALLEVEALPLQMCRHP-PREKTVLVGRRAVLEVTVS-RSGGHVCW-----LREG 1845
Query: 229 LIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTA 265
+ P Y LV+++ RPED G Y C A
Sbjct: 1846 AELCPGDKYEMRSHGPTHSLVIHDVRPEDQGTYCCQA 1882
>gi|224994173 roundabout 1 isoform d [Homo sapiens]
Length = 1551
Score = 62.8 bits (151), Expect = 8e-10
Identities = 31/102 (30%), Positives = 43/102 (42%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN 228
G E +A T PP P Q V +G T + C+ +G P PA+ W ++ Q
Sbjct: 298 GKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 357
Query: 229 LIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+P Q V+ G L + N + D G Y C N AG
Sbjct: 358 FSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAG 399
Score = 46.2 bits (108), Expect = 8e-05
Identities = 40/137 (29%), Positives = 54/137 (39%), Gaps = 30/137 (21%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + PS V G A+L+C GRP P + W K + E D + ++
Sbjct: 28 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVET---DKDDPRSHRMLLP 84
Query: 245 IGQLVLY------NARPEDAGLYTCTARNAAG------------LLRADFPLSVVQREPA 286
G L +RP D G+Y C ARN G +LR DF R+
Sbjct: 85 SGSLFFLRIVHGRKSRP-DEGVYVCVARNYLGEAVSHNASLEVAILRDDF------RQNP 137
Query: 287 RDAAPSI--PAPAECLP 301
D ++ PA EC P
Sbjct: 138 SDVMVAVGEPAVMECQP 154
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/123 (28%), Positives = 47/123 (38%), Gaps = 11/123 (8%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + P Q V V GT L C +G P P + W K R Q+
Sbjct: 418 PPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLEN------ 471
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV----VQREPARDAAPSIPAPAECL 300
G L + A+ D G YTC A +G + V V +P R P++ A
Sbjct: 472 -GVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSK 530
Query: 301 PDV 303
P+V
Sbjct: 531 PEV 533
Score = 42.4 bits (98), Expect = 0.001
Identities = 60/225 (26%), Positives = 83/225 (36%), Gaps = 24/225 (10%)
Query: 71 GLHSCVAARFPGSPAAPTTAASCEGFVCP----QQGSDCDIWDGQP-VCRCRD-RCEKEP 124
G++ CVA + G A + AS E + Q SD + G+P V C+ R EP
Sbjct: 104 GVYVCVARNYLGE--AVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEP 161
Query: 125 SFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPGAAPV 184
+ + DG ++ D +RG L I + + G R + A
Sbjct: 162 TISWKKDGSPLDDK---DERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELT 218
Query: 185 P---PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
P+ PS AV V +A C+ G P P V W K + P Y
Sbjct: 219 VLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGE------LPKSRY---E 269
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV-VQREP 285
+ L + D G YTC A N G A L+V V EP
Sbjct: 270 IRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEP 314
Score = 38.9 bits (89), Expect = 0.012
Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 9/103 (8%)
Query: 191 SPSPQAVQVGGTASLHCDVS-GRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLV 249
+PS V VG A + C G P P ++W+K ++ R + G+L+
Sbjct: 136 NPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLM 187
Query: 250 LYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPS 292
+ R DAG Y C N G ++ V P+ PS
Sbjct: 188 ITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPS 230
>gi|224994171 roundabout 1 isoform c [Homo sapiens]
Length = 1606
Score = 62.8 bits (151), Expect = 8e-10
Identities = 31/102 (30%), Positives = 43/102 (42%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN 228
G E +A T PP P Q V +G T + C+ +G P PA+ W ++ Q
Sbjct: 298 GKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 357
Query: 229 LIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+P Q V+ G L + N + D G Y C N AG
Sbjct: 358 FSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAG 399
Score = 46.2 bits (108), Expect = 8e-05
Identities = 40/137 (29%), Positives = 54/137 (39%), Gaps = 30/137 (21%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + PS V G A+L+C GRP P + W K + E D + ++
Sbjct: 28 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVET---DKDDPRSHRMLLP 84
Query: 245 IGQLVLY------NARPEDAGLYTCTARNAAG------------LLRADFPLSVVQREPA 286
G L +RP D G+Y C ARN G +LR DF R+
Sbjct: 85 SGSLFFLRIVHGRKSRP-DEGVYVCVARNYLGEAVSHNASLEVAILRDDF------RQNP 137
Query: 287 RDAAPSI--PAPAECLP 301
D ++ PA EC P
Sbjct: 138 SDVMVAVGEPAVMECQP 154
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/123 (28%), Positives = 47/123 (38%), Gaps = 11/123 (8%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + P Q V V GT L C +G P P + W K R Q+
Sbjct: 418 PPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLEN------ 471
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV----VQREPARDAAPSIPAPAECL 300
G L + A+ D G YTC A +G + V V +P R P++ A
Sbjct: 472 -GVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSK 530
Query: 301 PDV 303
P+V
Sbjct: 531 PEV 533
Score = 42.4 bits (98), Expect = 0.001
Identities = 60/225 (26%), Positives = 83/225 (36%), Gaps = 24/225 (10%)
Query: 71 GLHSCVAARFPGSPAAPTTAASCEGFVCP----QQGSDCDIWDGQP-VCRCRD-RCEKEP 124
G++ CVA + G A + AS E + Q SD + G+P V C+ R EP
Sbjct: 104 GVYVCVARNYLGE--AVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEP 161
Query: 125 SFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPGAAPV 184
+ + DG ++ D +RG L I + + G R + A
Sbjct: 162 TISWKKDGSPLDDK---DERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELT 218
Query: 185 P---PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
P+ PS AV V +A C+ G P P V W K + P Y
Sbjct: 219 VLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGE------LPKSRY---E 269
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV-VQREP 285
+ L + D G YTC A N G A L+V V EP
Sbjct: 270 IRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEP 314
Score = 38.9 bits (89), Expect = 0.012
Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 9/103 (8%)
Query: 191 SPSPQAVQVGGTASLHCDVS-GRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLV 249
+PS V VG A + C G P P ++W+K ++ R + G+L+
Sbjct: 136 NPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLM 187
Query: 250 LYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPS 292
+ R DAG Y C N G ++ V P+ PS
Sbjct: 188 ITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPS 230
>gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 2 [Homo sapiens]
Length = 117
Score = 62.8 bits (151), Expect = 8e-10
Identities = 27/70 (38%), Positives = 35/70 (50%)
Query: 346 ACQQACARGPGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESC 405
+C + C D C +P GPC + W Y C FVYGGC+GN NNF S+ +C
Sbjct: 48 SCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANC 107
Query: 406 EDACPVPRTP 415
+ C R P
Sbjct: 108 LNTCKNKRFP 117
Score = 33.9 bits (76), Expect = 0.40
Identities = 14/45 (31%), Positives = 19/45 (42%)
Query: 307 TGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQAC 351
TGP + + W YD + C F GC G F++ C C
Sbjct: 67 TGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 111
>gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 1 precursor [Homo sapiens]
Length = 133
Score = 62.8 bits (151), Expect = 8e-10
Identities = 27/70 (38%), Positives = 35/70 (50%)
Query: 346 ACQQACARGPGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESC 405
+C + C D C +P GPC + W Y C FVYGGC+GN NNF S+ +C
Sbjct: 64 SCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANC 123
Query: 406 EDACPVPRTP 415
+ C R P
Sbjct: 124 LNTCKNKRFP 133
Score = 33.9 bits (76), Expect = 0.40
Identities = 14/45 (31%), Positives = 19/45 (42%)
Query: 307 TGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQAC 351
TGP + + W YD + C F GC G F++ C C
Sbjct: 83 TGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 32.3 bits (72), Expect = 1.1
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 15/72 (20%)
Query: 4 LRPLLPLLLLLRLTSGAGLLPGLGSHPGVCPNQLSPNLWVDAQSTCERE----CSRDQDC 59
L LL L +LL G GL L P CP + CE + C++D+ C
Sbjct: 6 LLSLLVLFVLLANVQGPGLTDWL--FPRRCPK---------IREECEFQERDVCTKDRQC 54
Query: 60 AAAEKCCINVCG 71
+KCC+ CG
Sbjct: 55 QDNKKCCVFSCG 66
>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
sapiens]
Length = 1562
Score = 62.8 bits (151), Expect = 8e-10
Identities = 31/102 (30%), Positives = 43/102 (42%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN 228
G E +A T PP P Q V +G T + C+ +G P PA+ W ++ Q
Sbjct: 298 GKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 357
Query: 229 LIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+P Q V+ G L + N + D G Y C N AG
Sbjct: 358 FSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAG 399
Score = 46.2 bits (108), Expect = 8e-05
Identities = 40/137 (29%), Positives = 54/137 (39%), Gaps = 30/137 (21%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + PS V G A+L+C GRP P + W K + E D + ++
Sbjct: 28 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVET---DKDDPRSHRMLLP 84
Query: 245 IGQLVLY------NARPEDAGLYTCTARNAAG------------LLRADFPLSVVQREPA 286
G L +RP D G+Y C ARN G +LR DF R+
Sbjct: 85 SGSLFFLRIVHGRKSRP-DEGVYVCVARNYLGEAVSHNASLEVAILRDDF------RQNP 137
Query: 287 RDAAPSI--PAPAECLP 301
D ++ PA EC P
Sbjct: 138 SDVMVAVGEPAVMECQP 154
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/123 (28%), Positives = 47/123 (38%), Gaps = 11/123 (8%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + P Q V V GT L C +G P P + W K R Q+
Sbjct: 418 PPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLEN------ 471
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV----VQREPARDAAPSIPAPAECL 300
G L + A+ D G YTC A +G + V V +P R P++ A
Sbjct: 472 -GVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSK 530
Query: 301 PDV 303
P+V
Sbjct: 531 PEV 533
Score = 42.4 bits (98), Expect = 0.001
Identities = 60/225 (26%), Positives = 83/225 (36%), Gaps = 24/225 (10%)
Query: 71 GLHSCVAARFPGSPAAPTTAASCEGFVCP----QQGSDCDIWDGQP-VCRCRD-RCEKEP 124
G++ CVA + G A + AS E + Q SD + G+P V C+ R EP
Sbjct: 104 GVYVCVARNYLGE--AVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEP 161
Query: 125 SFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPGAAPV 184
+ + DG ++ D +RG L I + + G R + A
Sbjct: 162 TISWKKDGSPLDDK---DERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELT 218
Query: 185 P---PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
P+ PS AV V +A C+ G P P V W K + P Y
Sbjct: 219 VLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGE------LPKSRY---E 269
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV-VQREP 285
+ L + D G YTC A N G A L+V V EP
Sbjct: 270 IRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEP 314
Score = 38.9 bits (89), Expect = 0.012
Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 9/103 (8%)
Query: 191 SPSPQAVQVGGTASLHCDVS-GRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLV 249
+PS V VG A + C G P P ++W+K ++ R + G+L+
Sbjct: 136 NPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLM 187
Query: 250 LYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPS 292
+ R DAG Y C N G ++ V P+ PS
Sbjct: 188 ITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPS 230
>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
sapiens]
Length = 1615
Score = 62.8 bits (151), Expect = 8e-10
Identities = 31/102 (30%), Positives = 43/102 (42%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN 228
G E +A T PP P Q V +G T + C+ +G P PA+ W ++ Q
Sbjct: 298 GKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 357
Query: 229 LIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+P Q V+ G L + N + D G Y C N AG
Sbjct: 358 FSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAG 399
Score = 46.2 bits (108), Expect = 8e-05
Identities = 40/137 (29%), Positives = 54/137 (39%), Gaps = 30/137 (21%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + PS V G A+L+C GRP P + W K + E D + ++
Sbjct: 28 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVET---DKDDPRSHRMLLP 84
Query: 245 IGQLVLY------NARPEDAGLYTCTARNAAG------------LLRADFPLSVVQREPA 286
G L +RP D G+Y C ARN G +LR DF R+
Sbjct: 85 SGSLFFLRIVHGRKSRP-DEGVYVCVARNYLGEAVSHNASLEVAILRDDF------RQNP 137
Query: 287 RDAAPSI--PAPAECLP 301
D ++ PA EC P
Sbjct: 138 SDVMVAVGEPAVMECQP 154
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/123 (28%), Positives = 47/123 (38%), Gaps = 11/123 (8%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + P Q V V GT L C +G P P + W K R Q+
Sbjct: 418 PPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLEN------ 471
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV----VQREPARDAAPSIPAPAECL 300
G L + A+ D G YTC A +G + V V +P R P++ A
Sbjct: 472 -GVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSK 530
Query: 301 PDV 303
P+V
Sbjct: 531 PEV 533
Score = 42.4 bits (98), Expect = 0.001
Identities = 60/225 (26%), Positives = 83/225 (36%), Gaps = 24/225 (10%)
Query: 71 GLHSCVAARFPGSPAAPTTAASCEGFVCP----QQGSDCDIWDGQP-VCRCRD-RCEKEP 124
G++ CVA + G A + AS E + Q SD + G+P V C+ R EP
Sbjct: 104 GVYVCVARNYLGE--AVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEP 161
Query: 125 SFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPGAAPV 184
+ + DG ++ D +RG L I + + G R + A
Sbjct: 162 TISWKKDGSPLDDK---DERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELT 218
Query: 185 P---PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
P+ PS AV V +A C+ G P P V W K + P Y
Sbjct: 219 VLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGE------LPKSRY---E 269
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV-VQREP 285
+ L + D G YTC A N G A L+V V EP
Sbjct: 270 IRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEP 314
Score = 38.9 bits (89), Expect = 0.012
Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 9/103 (8%)
Query: 191 SPSPQAVQVGGTASLHCDVS-GRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLV 249
+PS V VG A + C G P P ++W+K ++ R + G+L+
Sbjct: 136 NPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLM 187
Query: 250 LYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPS 292
+ R DAG Y C N G ++ V P+ PS
Sbjct: 188 ITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPS 230
>gi|145309328 papilin [Homo sapiens]
Length = 1251
Score = 62.8 bits (151), Expect = 8e-10
Identities = 26/65 (40%), Positives = 34/65 (52%), Gaps = 4/65 (6%)
Query: 349 QACARGPGDA----CVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRES 404
+ C P A C+LP+ G C W RW + + QC+ F YGGC GN NNF S +
Sbjct: 713 EGCVGQPSHAYPVRCLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQE 772
Query: 405 CEDAC 409
C +C
Sbjct: 773 CMSSC 777
Score = 37.0 bits (84), Expect = 0.047
Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 17/72 (23%)
Query: 200 GGTASLHCDVSGRPPPAVTWEKQ----SHQRENLIMRPDQMYGNVVVTSIGQLVLYNARP 255
G + C G PPPA+ W++ S R L +PD G LV+
Sbjct: 1031 GQRIRMTCRAEGFPPPAIEWQRDGQPVSSPRHQL--QPD-----------GSLVISRVAV 1077
Query: 256 EDAGLYTCTARN 267
ED G YTC A N
Sbjct: 1078 EDGGFYTCVAFN 1089
Score = 37.0 bits (84), Expect = 0.047
Identities = 35/116 (30%), Positives = 46/116 (39%), Gaps = 18/116 (15%)
Query: 192 PSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI-GQLVL 250
P V G TA L C V+G + W + P Q G+ V S G L++
Sbjct: 1112 PPTVTVPEGDTARLLCVVAGESVN-IRWSRNG--------LPVQADGHRVHQSPDGTLLI 1162
Query: 251 YNARPEDAGLYTCTARNAAGLLRADFPLSVVQ-------REPARDAAPSIPAPAEC 299
YN R D G YTC+A + + + VV R+P RD P A C
Sbjct: 1163 YNLRARDEGSYTCSAYQGSQAVSRSTEVKVVSPAPTAQPRDPGRDCVDQ-PELANC 1217
Score = 32.7 bits (73), Expect = 0.88
Identities = 17/61 (27%), Positives = 25/61 (40%), Gaps = 2/61 (3%)
Query: 291 PSIPAPAECLPDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQA 350
PS P CL + + G + W++ G C F GC G A F + + C +
Sbjct: 719 PSHAYPVRCL--LPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSS 776
Query: 351 C 351
C
Sbjct: 777 C 777
Score = 29.3 bits (64), Expect = 9.7
Identities = 24/97 (24%), Positives = 37/97 (38%), Gaps = 15/97 (15%)
Query: 167 SPGPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQR 226
SP PP ++ A V P+L + Q V+ L C P W+K
Sbjct: 870 SPAPPFHSSSYRISLAGVEPSLVQAALGQLVR------LSCSDDTAPESQAAWQKDGQPI 923
Query: 227 ENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTC 263
+ R + G L+++ + EDAG Y+C
Sbjct: 924 SSDRHR---------LQFDGSLIIHPLQAEDAGTYSC 951
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 62.4 bits (150), Expect = 1e-09
Identities = 41/132 (31%), Positives = 52/132 (39%), Gaps = 9/132 (6%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
V P S PS V+VG L C G P PA+TW K Q G ++
Sbjct: 523 VTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTE--------SGKFHIS 574
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAP-AECLPD 302
G L + + P DAG Y C ARN G LSV + +R+ P + E +
Sbjct: 575 PEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVATSIVEAIAT 634
Query: 303 VQACTGPTSPHL 314
V T HL
Sbjct: 635 VDRAINSTRTHL 646
Score = 46.6 bits (109), Expect = 6e-05
Identities = 31/115 (26%), Positives = 46/115 (40%), Gaps = 6/115 (5%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P + S P V G T C G P P + W + +++ L M+ D +
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNE---LSMKTDSRLN---LLDD 299
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECL 300
G L++ N + D G+Y C A+N AG ++ PAR P E L
Sbjct: 300 GTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVL 354
Score = 46.6 bits (109), Expect = 6e-05
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 7/86 (8%)
Query: 182 APVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
+P P P V VG + +L C +G PPP ++W + R L + P V
Sbjct: 338 SPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR--GDRTPLPVDP-----RVN 390
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARN 267
+T G L + N D+G Y C+A N
Sbjct: 391 ITPSGGLYIQNVVQGDSGEYACSATN 416
Score = 42.7 bits (99), Expect = 9e-04
Identities = 36/137 (26%), Positives = 52/137 (37%), Gaps = 10/137 (7%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P +P + V G T C+ G PPP + W K Q + D+ + +V S
Sbjct: 433 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQ-----LSVDRRH---LVLSS 484
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQ- 304
G L + D G Y C A N G + L+V R A+ E +VQ
Sbjct: 485 GTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQL 544
Query: 305 ACTGPTSPH-LVLWHYD 320
C+ P + W+ D
Sbjct: 545 PCSSQGEPEPAITWNKD 561
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 60.8 bits (146), Expect = 3e-09
Identities = 33/96 (34%), Positives = 42/96 (43%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP P Q V G T + C+ G P PAV W+K+ Q +P Q V+
Sbjct: 329 PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP 388
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
G L + N + DAG Y C A AG + A L V
Sbjct: 389 TGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEV 424
Score = 50.1 bits (118), Expect = 5e-06
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 7/86 (8%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + P+ Q + V GTA L C +G P P ++W K+ R +
Sbjct: 433 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPR-------ATIQE 485
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG 270
G L + N R D G YTC A +++G
Sbjct: 486 QGTLQIKNLRISDTGTYTCVATSSSG 511
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/137 (29%), Positives = 53/137 (38%), Gaps = 30/137 (21%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + PS V G +L+C GRP P + W K + E D + ++
Sbjct: 46 PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVET---DKDDPRSHRMLLP 102
Query: 245 IGQL----VLYNARPE-DAGLYTCTARNAAG------------LLRADF---PLSVVQRE 284
G L +++ R + D G Y C ARN G LLR DF P VV
Sbjct: 103 SGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVV--- 159
Query: 285 PARDAAPSIPAPAECLP 301
A PA EC P
Sbjct: 160 ----VAAGEPAILECQP 172
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 9/81 (11%)
Query: 191 SPSPQAVQVGGTASLHCDVS-GRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLV 249
+P+ V G A L C G P P + W+K +R D + + G+L+
Sbjct: 154 NPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDK-------VRIDDKEERISIRG-GKLM 205
Query: 250 LYNARPEDAGLYTCTARNAAG 270
+ N R DAG+YTC N G
Sbjct: 206 ISNTRKSDAGMYTCVGTNMVG 226
Score = 35.8 bits (81), Expect = 0.10
Identities = 25/95 (26%), Positives = 30/95 (31%), Gaps = 9/95 (9%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P P Q V C V G P P V W+K D G +
Sbjct: 241 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDD---------ADLPRGRYDIKDD 291
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
L + D G Y C A N G + A L+V
Sbjct: 292 YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 326
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 60.8 bits (146), Expect = 3e-09
Identities = 33/96 (34%), Positives = 42/96 (43%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP P Q V G T + C+ G P PAV W+K+ Q +P Q V+
Sbjct: 313 PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP 372
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
G L + N + DAG Y C A AG + A L V
Sbjct: 373 TGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEV 408
Score = 50.1 bits (118), Expect = 5e-06
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 7/86 (8%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + P+ Q + V GTA L C +G P P ++W K+ R +
Sbjct: 417 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPR-------ATIQE 469
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG 270
G L + N R D G YTC A +++G
Sbjct: 470 QGTLQIKNLRISDTGTYTCVATSSSG 495
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/137 (29%), Positives = 53/137 (38%), Gaps = 30/137 (21%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + PS V G +L+C GRP P + W K + E D + ++
Sbjct: 30 PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVET---DKDDPRSHRMLLP 86
Query: 245 IGQL----VLYNARPE-DAGLYTCTARNAAG------------LLRADF---PLSVVQRE 284
G L +++ R + D G Y C ARN G LLR DF P VV
Sbjct: 87 SGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVV--- 143
Query: 285 PARDAAPSIPAPAECLP 301
A PA EC P
Sbjct: 144 ----VAAGEPAILECQP 156
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 9/81 (11%)
Query: 191 SPSPQAVQVGGTASLHCDVS-GRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLV 249
+P+ V G A L C G P P + W+K +R D + + G+L+
Sbjct: 138 NPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDK-------VRIDDKEERISIRG-GKLM 189
Query: 250 LYNARPEDAGLYTCTARNAAG 270
+ N R DAG+YTC N G
Sbjct: 190 ISNTRKSDAGMYTCVGTNMVG 210
Score = 35.8 bits (81), Expect = 0.10
Identities = 25/95 (26%), Positives = 30/95 (31%), Gaps = 9/95 (9%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P P Q V C V G P P V W+K D G +
Sbjct: 225 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDD---------ADLPRGRYDIKDD 275
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
L + D G Y C A N G + A L+V
Sbjct: 276 YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 310
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 60.1 bits (144), Expect = 5e-09
Identities = 36/112 (32%), Positives = 46/112 (41%), Gaps = 15/112 (13%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSH----QRENLIMRPDQMYGN 239
VPP + P VQVG + C+ G P P +TW K E+ + PD
Sbjct: 1169 VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPD----- 1223
Query: 240 VVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAP 291
G L + A P DAG+YTC A N AG + L V + D P
Sbjct: 1224 ------GTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEP 1269
Score = 57.8 bits (138), Expect = 3e-08
Identities = 32/87 (36%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
VPP + S+ V A L C G P PA+ W+K + NL+ G
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL-------GKYTAE 4219
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAG 270
G+L+L N ED+G YTC A NAAG
Sbjct: 4220 PYGELILENVVLEDSGFYTCVANNAAG 4246
Score = 57.0 bits (136), Expect = 4e-08
Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 6/129 (4%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
VPP++ P+ V V +L C+ +G P P++ W K H ++ DQ + +
Sbjct: 3802 VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGH-----LLNVDQNQNSYRLL 3856
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDV 303
S G LV+ + +D Y CT N AG + L+ VQ P+ P+ + P V
Sbjct: 3857 SSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLT-VQVPPSIADEPTDFLVTKHAPAV 3915
Query: 304 QACTGPTSP 312
CT P
Sbjct: 3916 ITCTASGVP 3924
Score = 56.2 bits (134), Expect = 7e-08
Identities = 51/198 (25%), Positives = 74/198 (37%), Gaps = 21/198 (10%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + P + GG L+C +G P P +TW +Q H I D+ V V S
Sbjct: 4439 PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHS----ISWDDR----VNVLS 4490
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQ 304
L + +A+ ED + C ARN G + P+ V + C +Q
Sbjct: 4491 NNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQ 4550
Query: 305 ----ACTGPTSPH--LVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGD- 357
C P + D + C P DG+ + +E C ++C RG
Sbjct: 4551 KRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPC-PVDGSWSEWSLWEECTRSCGRGNQTR 4609
Query: 358 --ACVLPAVQ---GPCRG 370
C P+VQ PC G
Sbjct: 4610 TRTCNNPSVQHGGRPCEG 4627
Score = 55.8 bits (133), Expect = 1e-07
Identities = 53/215 (24%), Positives = 75/215 (34%), Gaps = 9/215 (4%)
Query: 67 INVCGLHSCVAARFPGSPAAPTTAASCEGFVCPQQGSDCDIWDGQPVCR-CRDRCEKEPS 125
+N G ++CVA GS T E V Q S+ + P+ C P
Sbjct: 3959 LNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPF 4018
Query: 126 FTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPGAAPVP 185
T +G+ A GL + + ++ + P T VP
Sbjct: 4019 ITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVP 4078
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P + + V +L C+ G PPP +TW K I + V S
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQR--------VLSS 4130
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
G L + +P DAG YTC A N AG L+V
Sbjct: 4131 GSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 54.3 bits (129), Expect = 3e-07
Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 12/101 (11%)
Query: 185 PPAL---YSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
PP++ + SP +V + SL C+ SG P P++TW K P + +V
Sbjct: 2383 PPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGW--------PVSLSNSVR 2434
Query: 242 VTSIGQLV-LYNARPEDAGLYTCTARNAAGLLRADFPLSVV 281
+ S G+++ L EDAG YTC RNAAG R F LSV+
Sbjct: 2435 ILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475
Score = 53.1 bits (126), Expect = 6e-07
Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 8/89 (8%)
Query: 192 PSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLY 251
PS +GG A L+C+V G P P + W ++ E I + GN G L +Y
Sbjct: 4356 PSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIE--ISHRIRQLGN------GSLAIY 4407
Query: 252 NARPEDAGLYTCTARNAAGLLRADFPLSV 280
EDAG YTC A N AG++ L++
Sbjct: 4408 GTVNEDAGDYTCVATNEAGVVERSMSLTL 4436
Score = 51.2 bits (121), Expect = 2e-06
Identities = 33/92 (35%), Positives = 41/92 (44%), Gaps = 9/92 (9%)
Query: 190 SSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLV 249
S P+ V G + SL C+V G PPP VTW K H P V + G ++
Sbjct: 2297 SHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGH--------PLIKAKGVEILDEGHIL 2348
Query: 250 -LYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
L N D G Y C A N AG+ + LSV
Sbjct: 2349 QLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380
Score = 50.4 bits (119), Expect = 4e-06
Identities = 34/99 (34%), Positives = 49/99 (49%), Gaps = 10/99 (10%)
Query: 184 VPPALYSSPSPQ-AVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVV 242
VPP++ S V V SL C+VSG PPP ++W K +P ++ N ++
Sbjct: 2962 VPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNE--------QPIKLNTNTLI 3013
Query: 243 TSIGQ-LVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
G+ L + A+ D G YTC A N AG + F L+V
Sbjct: 3014 VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052
Score = 50.1 bits (118), Expect = 5e-06
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 8/98 (8%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + P Q+ G S+ C +G P P + W ++ + Y +TS
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN-----DMFIVGSHRYR---MTS 662
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQ 282
G L + NA P+DAG+Y C A N+AG + + L ++
Sbjct: 663 DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE 700
Score = 50.1 bits (118), Expect = 5e-06
Identities = 47/157 (29%), Positives = 65/157 (41%), Gaps = 14/157 (8%)
Query: 184 VPPALYSSPSPQAVQVG-GTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVV 242
VPP + SS + V V +L C +G P P++TW K + GN+ +
Sbjct: 1824 VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP-------VNTAQGNLKI 1876
Query: 243 TSIGQLV-LYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLP 301
S G+++ + EDAG YTC A NAAG + L V + DA +
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSN 1936
Query: 302 DVQ-ACTGPTSPHLVLWHYDPQR----GGCMTFPARG 333
VQ C +P V+ Y R MTF RG
Sbjct: 1937 PVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRG 1973
Score = 49.3 bits (116), Expect = 9e-06
Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 9/103 (8%)
Query: 184 VPPALYSSPSPQAVQV--GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
VPP + S + V G SL C+ SG PPP + W+K+ + D M G V
Sbjct: 2193 VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSP-----VLTDSM-GRVR 2246
Query: 242 VTSIG-QLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
+ S G QL + A DA LY+C A N AG + ++ L V R
Sbjct: 2247 ILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIR 2289
Score = 48.5 bits (114), Expect = 2e-05
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 9/99 (9%)
Query: 184 VPPALYSSPSPQ--AVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
VPPA+ V V L C V+G PPP + W K LI D+ G +
Sbjct: 1731 VPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQ----LI---DERDGFKI 1783
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
+ + +LV+ A+ + GLY C A N AG + +F ++V
Sbjct: 1784 LLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTV 1822
Score = 48.1 bits (113), Expect = 2e-05
Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 10/99 (10%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGN-VVV 242
V P++ S + AV V L C+ G P P++TW K P + N + V
Sbjct: 2010 VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDG--------SPVSSFSNGLQV 2061
Query: 243 TSIGQ-LVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
S G+ L L +A+ D G YTC A NAAG + D L V
Sbjct: 2062 LSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Score = 47.8 bits (112), Expect = 3e-05
Identities = 35/120 (29%), Positives = 51/120 (42%), Gaps = 12/120 (10%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQ-LVLYNARP 255
V + SL+C+ + PPP +TW K H P V++ G+ L + A+
Sbjct: 2789 VIINNPISLYCETNAAPPPTLTWYKDGH--------PLTSSDKVLILPGGRVLQIPRAKV 2840
Query: 256 EDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQA---CTGPTSP 312
EDAG YTC A N AG + + V+ + A +P L + A C SP
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSP 2900
Score = 47.0 bits (110), Expect = 5e-05
Identities = 24/96 (25%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP P+ ++++G +L C V G P P + W + + + RP + ++
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNM--PIFSRPFSV-SSISQLR 848
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
G L + N D G Y C A N G ++++ ++V
Sbjct: 849 TGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884
Score = 47.0 bits (110), Expect = 5e-05
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 7/97 (7%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
VPP + +V + L C PPP +TW K H L+ +P G +
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHP---LLKKP----GLSISE 2154
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
+ L + +A+ +D G YTC A N AG ++ +++
Sbjct: 2155 NRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191
Score = 46.2 bits (108), Expect = 8e-05
Identities = 34/100 (34%), Positives = 45/100 (45%), Gaps = 10/100 (10%)
Query: 184 VPPALYSSPSPQAVQV--GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
VPP + + P V V +L C V G P P + W K + + P NV
Sbjct: 1450 VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDG--KPLFLGDP-----NVE 1502
Query: 242 VTSIGQLV-LYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
+ GQ++ L NAR D G Y CT NAAG D L++
Sbjct: 1503 LLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 45.8 bits (107), Expect = 1e-04
Identities = 34/111 (30%), Positives = 45/111 (40%), Gaps = 9/111 (8%)
Query: 173 TTARPTPGAAPVPPALYSSPSPQAVQV--GGTASLHCDVSGRPPPAVTWEKQSHQRENLI 230
TT R VPP + V V +L C+V G P P + W K + Q
Sbjct: 1346 TTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESS 1405
Query: 231 MRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVV 281
G + L L+ A PEDAG Y+C A N AG + F + V+
Sbjct: 1406 TIQTVNNGKI-------LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449
Score = 45.4 bits (106), Expect = 1e-04
Identities = 29/101 (28%), Positives = 50/101 (49%), Gaps = 11/101 (10%)
Query: 185 PPALYSSPSPQAVQV--GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVV 242
PP + +S + + V G + S+ C G P P++ W + +P + ++ V
Sbjct: 3433 PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDG--------QPLGLDAHLTV 3484
Query: 243 TSIGQLV-LYNARPEDAGLYTCTARNAAGLLRADFPLSVVQ 282
++ G ++ L A ED+G YTC A N AG + F L V++
Sbjct: 3485 STHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLE 3525
Score = 45.1 bits (105), Expect = 2e-04
Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 8/118 (6%)
Query: 184 VPPALYSSPSPQAVQ-VGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVV 242
VPP++ V+ + +L CD +G PPP + W K + EN D + ++
Sbjct: 3149 VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIEN----SDSLEVR-IL 3203
Query: 243 TSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECL 300
+ +L + ++ D+G YTC A N G + + LS+ + P A IP+ L
Sbjct: 3204 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI--QVPPSVAGAEIPSDVSVL 3259
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
VPP++ P+ V A + C SG P P++ W K + L+ R D +
Sbjct: 3895 VPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIR---LLPRGD----GYRIL 3947
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAG 270
S G + + + AG YTC ARNAAG
Sbjct: 3948 SSGAIEILATQLNHAGRYTCVARNAAG 3974
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 7/95 (7%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P L S V +G + C SG PPP V W K +L +RP ++ +
Sbjct: 702 PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK-----GDLELRPSTFL--IIDPLL 754
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
G L + + DAG YTC A N AG L V
Sbjct: 755 GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDV 789
Score = 43.5 bits (101), Expect = 5e-04
Identities = 37/118 (31%), Positives = 52/118 (44%), Gaps = 20/118 (16%)
Query: 184 VPPAL--YSSPSPQAVQV--GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGN 239
VPP++ + S S V V G + SL C+ + PPP +TW K R +
Sbjct: 3054 VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNG--------RMITESTH 3105
Query: 240 VVVTSIGQLV-LYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAP 296
V + + GQ++ + A D G Y C A N AG +F L+V PSI P
Sbjct: 3106 VEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY-------VPPSIEGP 3156
Score = 43.1 bits (100), Expect = 7e-04
Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 12/99 (12%)
Query: 192 PSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLY 251
P +V G +L C+V PPP +TW K E ++ P + + G + +
Sbjct: 1086 PVEISVLAGEEVTLPCEVKSLPPPIITWAK-----ETQLISPFSPRHTFLPS--GSMKIT 1138
Query: 252 NARPEDAGLYTCTARNAAGLLRADFPLSV-----VQREP 285
R D+G+Y C A N AG + L+V +QR P
Sbjct: 1139 ETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP 1177
Score = 42.7 bits (99), Expect = 9e-04
Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 15/101 (14%)
Query: 185 PPALYSSPSP--QAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVV 242
PP+L + + V V L C +G P P +TW K + + G+ +
Sbjct: 1918 PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRL----------LSGSTSM 1967
Query: 243 TSI--GQLV-LYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
T + GQ++ + +A+ DAG+Y C A N+AG + L V
Sbjct: 1968 TFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 42.7 bits (99), Expect = 9e-04
Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 7/97 (7%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
VPP + P + + + L C G P P +TW K + ++ + + +
Sbjct: 3711 VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRK-----DGAVLAGN--HARYSIL 3763
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
G L + +A D G Y C A NAAG R L V
Sbjct: 3764 ENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 41.6 bits (96), Expect = 0.002
Identities = 36/139 (25%), Positives = 55/139 (39%), Gaps = 10/139 (7%)
Query: 184 VPPALYSS--PSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
VPP++ + PS +V +G L C+ +G P P + W K + + V
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKP-----IASGETERIRV 3297
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPAR---DAAPSIPAPAE 298
+ L +Y A D G YTC A N AG F L+V R D A + +
Sbjct: 3298 SANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVD 3357
Query: 299 CLPDVQACTGPTSPHLVLW 317
+++ T P + W
Sbjct: 3358 TSINIECRATGTPPPQINW 3376
Score = 41.2 bits (95), Expect = 0.002
Identities = 59/251 (23%), Positives = 87/251 (34%), Gaps = 42/251 (16%)
Query: 40 NLWVDAQST--CERECSRDQDCAAAEKCCINVCGLHSCVAARFPGSPAAPTTAASCEGFV 97
NLW + T CE E +Q + + V GL + P +P+ A EG
Sbjct: 856 NLWASDKGTYICEAE---NQFGKIQSETTVTVTGLVA------PLIGISPSVANVIEG-- 904
Query: 98 CPQQGSDCDIWDGQPVCRCR-----DRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLHL 152
Q C + G P+ R + P T SDG LH+
Sbjct: 905 -QQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG----------------SLHI 947
Query: 153 HIVPCKHVLSWPPSSPGPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGR 212
V + + + T + T V P + + G +L C SG
Sbjct: 948 ERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGN 1007
Query: 213 PPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLL 272
P P+V W K+ LI + + G L + + E++G Y CTA N AG
Sbjct: 1008 PKPSVIWSKKG----ELISTSSAKFS---AGADGSLYVVSPGGEESGEYVCTATNTAGYA 1060
Query: 273 RADFPLSVVQR 283
+ L+V R
Sbjct: 1061 KRKVQLTVYVR 1071
Score = 40.8 bits (94), Expect = 0.003
Identities = 32/100 (32%), Positives = 44/100 (44%), Gaps = 11/100 (11%)
Query: 184 VPPALYSSPSPQAVQV--GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
VPP + + P+ + V +L C PPP +TW + E L P V
Sbjct: 3618 VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNG---ERLQATP-----RVR 3669
Query: 242 VTSIGQ-LVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
+ S G+ L + NA D YTC A N AG +F L+V
Sbjct: 3670 ILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Score = 40.4 bits (93), Expect = 0.004
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 11/92 (11%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRP-DQMYGNVVV 242
V P P ++ G L C +G P P +TW + N+I D + G+
Sbjct: 4258 VLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN----NIIPAHFDSVNGH--- 4310
Query: 243 TSIGQLVLYNARPEDAGLYTCTARNAAGLLRA 274
+LV+ ED+G Y CTA N+ G ++A
Sbjct: 4311 ---SELVIERVSKEDSGTYVCTAENSVGFVKA 4339
Score = 40.0 bits (92), Expect = 0.006
Identities = 40/136 (29%), Positives = 54/136 (39%), Gaps = 11/136 (8%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDV-SGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVV 242
V P + SPS V G +L C + +G P P W K S L+ P + V
Sbjct: 888 VAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAM---LLQNP-----YITV 939
Query: 243 TSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPD 302
S G L + + +D G YTC A N AG + VV P I + E +P
Sbjct: 940 RSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSV-VVHVLPTIQHGQQILSTIEGIPV 998
Query: 303 VQACTGPTSPH-LVLW 317
C +P V+W
Sbjct: 999 TLPCKASGNPKPSVIW 1014
Score = 40.0 bits (92), Expect = 0.006
Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 9/99 (9%)
Query: 184 VPPALYSSPSPQAVQVGGTAS--LHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
VPP + + + V+V S L C+V+G P P +TW K ++ D+ + +
Sbjct: 2476 VPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQP-----LQEDEAHH--I 2528
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
++ L + N + G YTC A + AG F L+V
Sbjct: 2529 ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 40.0 bits (92), Expect = 0.006
Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 9/83 (10%)
Query: 199 VGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLV-LYNARPED 257
V + ++ C +G PPP + W K P + ++ + + GQ++ + A+ D
Sbjct: 3356 VDTSINIECRATGTPPPQINWLKNG--------LPLPLSSHIRLLAAGQVIRIVRAQVSD 3407
Query: 258 AGLYTCTARNAAGLLRADFPLSV 280
+YTC A N AG+ + L V
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQV 3430
Score = 39.7 bits (91), Expect = 0.007
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 9/91 (9%)
Query: 191 SPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQ-LV 249
SP ++V T +L C+ P +++W K +P + +V + + G L
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASLSWYKDG--------QPLKSDDHVNIAANGHTLQ 2731
Query: 250 LYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
+ A+ D G YTC A N AG DF +++
Sbjct: 2732 IKEAQISDTGRYTCVASNIAGEDELDFDVNI 2762
Score = 39.7 bits (91), Expect = 0.007
Identities = 32/113 (28%), Positives = 46/113 (40%), Gaps = 17/113 (15%)
Query: 185 PPALYSSPSPQAVQV--GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVV 242
PP + S + + V L C SG P P +TW K RP V
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDG--------RPLPQTDQVQT 3577
Query: 243 TSIGQLV-LYNARPEDAGLYTCTARNAAG------LLRADFPLSVVQREPARD 288
G+++ + A+ ED G YTC A + AG L+R P ++ + RD
Sbjct: 3578 LGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRD 3630
Score = 39.3 bits (90), Expect = 0.009
Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 9/91 (9%)
Query: 191 SPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQ-LV 249
+P V + SL C+ PP +TW K P + N+ + G+ L
Sbjct: 2581 NPEDVTVILNSPTSLVCEAYSYPPATITWFKDG--------TPLESNRNIRILPGGRTLQ 2632
Query: 250 LYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
+ NA+ ++AG Y+C A N AG + + + V
Sbjct: 2633 ILNAQEDNAGRYSCVATNEAGEMIKHYEVKV 2663
Score = 38.5 bits (88), Expect = 0.016
Identities = 26/100 (26%), Positives = 40/100 (40%), Gaps = 11/100 (11%)
Query: 184 VPPALYSS--PSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
+PP++ + +V + L C+ G P PA+TW K +P +
Sbjct: 1544 IPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDG--------QPIMSSSQAL 1595
Query: 242 VTSIGQ-LVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
GQ L + A+ D+ YTC N AG F + V
Sbjct: 1596 YIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Score = 37.7 bits (86), Expect = 0.027
Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 12/102 (11%)
Query: 184 VPPAL---YSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNV 240
VPP + ++P + V + + +L C +G P P +TW K P + N+
Sbjct: 1637 VPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDG--------VPVKANDNI 1688
Query: 241 VVTSIG-QLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVV 281
+ + G +L + +A+ D G Y C A + AG + + V+
Sbjct: 1689 RIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVL 1730
Score = 37.7 bits (86), Expect = 0.027
Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 11/101 (10%)
Query: 184 VPPALYSS----PSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGN 239
VPP + + P V V +A + C SG P P +W+K ++ D +
Sbjct: 2867 VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQP----LLEDDH---H 2919
Query: 240 VVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
+++ L + N + D G Y C A N AG + F L+V
Sbjct: 2920 KFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2960
Score = 32.0 bits (71), Expect = 1.5
Identities = 27/120 (22%), Positives = 44/120 (36%), Gaps = 16/120 (13%)
Query: 207 CDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTAR 266
C G P P + W H L R G ++ LV+ + P D G Y C A
Sbjct: 1288 CPAKGTPKPTIKW---LHNGRELTGREP---GISILEDGTLLVIASVTPYDNGEYICVAV 1341
Query: 267 NAAGL------LRADFPLSVVQREPARDAAPSIPAPAECLPDVQACTGPTSPHLVLWHYD 320
N AG L+ P + +E + + + +V+ P +++W+ D
Sbjct: 1342 NEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSP----IIMWYKD 1397
>gi|153946389 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 60.1 bits (144), Expect = 5e-09
Identities = 26/64 (40%), Positives = 34/64 (53%)
Query: 346 ACQQACARGPGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESC 405
ACQ+ C + C+LP G C RW + +C PF Y GCEGN NNF + ++C
Sbjct: 82 ACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC 141
Query: 406 EDAC 409
AC
Sbjct: 142 RTAC 145
Score = 38.9 bits (89), Expect = 0.012
Identities = 15/35 (42%), Positives = 20/35 (57%)
Query: 317 WHYDPQRGGCMTFPARGCDGAARGFETYEACQQAC 351
WH+D + C F RGC+G A F +AC+ AC
Sbjct: 111 WHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
Score = 33.5 bits (75), Expect = 0.52
Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 14/68 (20%)
Query: 7 LLPLLLLLRLTSGAGLLPGLGSHPGVCPNQLSPNLWVDAQSTCERE----CSRDQDCAAA 62
LL L L L TS A L + PG+CP + + TC E C+ D DC
Sbjct: 26 LLLLSLALEWTS-AMLTKKIKHKPGLCPKE---------RLTCTTELPDSCNTDFDCKEY 75
Query: 63 EKCCINVC 70
+KCC C
Sbjct: 76 QKCCFFAC 83
Score = 29.3 bits (64), Expect = 9.7
Identities = 10/23 (43%), Positives = 12/23 (52%)
Query: 49 CERECSRDQDCAAAEKCCINVCG 71
C C D DC +KCC + CG
Sbjct: 165 CPPSCHSDIDCPQTDKCCESRCG 187
>gi|153946387 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 60.1 bits (144), Expect = 5e-09
Identities = 26/64 (40%), Positives = 34/64 (53%)
Query: 346 ACQQACARGPGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESC 405
ACQ+ C + C+LP G C RW + +C PF Y GCEGN NNF + ++C
Sbjct: 82 ACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC 141
Query: 406 EDAC 409
AC
Sbjct: 142 RTAC 145
Score = 38.9 bits (89), Expect = 0.012
Identities = 15/35 (42%), Positives = 20/35 (57%)
Query: 317 WHYDPQRGGCMTFPARGCDGAARGFETYEACQQAC 351
WH+D + C F RGC+G A F +AC+ AC
Sbjct: 111 WHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
Score = 33.5 bits (75), Expect = 0.52
Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 14/68 (20%)
Query: 7 LLPLLLLLRLTSGAGLLPGLGSHPGVCPNQLSPNLWVDAQSTCERE----CSRDQDCAAA 62
LL L L L TS A L + PG+CP + + TC E C+ D DC
Sbjct: 26 LLLLSLALEWTS-AMLTKKIKHKPGLCPKE---------RLTCTTELPDSCNTDFDCKEY 75
Query: 63 EKCCINVC 70
+KCC C
Sbjct: 76 QKCCFFAC 83
Score = 29.3 bits (64), Expect = 9.7
Identities = 10/23 (43%), Positives = 12/23 (52%)
Query: 49 CERECSRDQDCAAAEKCCINVCG 71
C C D DC +KCC + CG
Sbjct: 165 CPPSCHSDIDCPQTDKCCESRCG 187
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 59.7 bits (143), Expect = 7e-09
Identities = 38/110 (34%), Positives = 55/110 (50%), Gaps = 6/110 (5%)
Query: 172 ETTARPTPGAAPV-PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLI 230
ET P P PV PP L S V G + +L C +SG P P VTW ++ +Q E+ I
Sbjct: 928 ETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSI 987
Query: 231 MRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
+ + I +L++ A ED+G +TC+A N AG + L+V
Sbjct: 988 -----DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 52.4 bits (124), Expect = 1e-06
Identities = 37/124 (29%), Positives = 51/124 (41%), Gaps = 21/124 (16%)
Query: 182 APVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN----LIMRPDQMY 237
AP PP + P VQ G A +SGRP P ++W K+ + Q Y
Sbjct: 3235 APEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3294
Query: 238 GNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPA 297
L+L A PEDA +YTC A+N G+ LSV P + +P
Sbjct: 3295 ---------TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV--------EVPEVVSPD 3337
Query: 298 ECLP 301
+ +P
Sbjct: 3338 QEMP 3341
Score = 45.8 bits (107), Expect = 1e-04
Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
P L P + G + L C +SG P P VTW + ++++ +Q + V
Sbjct: 4158 PKMLQEMPKHARCREGDSIILECLISGEPQPVVTW-----FQNGVLLKQNQKFQFEEVNC 4212
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
QL + + +D+G Y C A N +G + + L+V
Sbjct: 4213 SHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTV 4248
Score = 43.5 bits (101), Expect = 5e-04
Identities = 32/111 (28%), Positives = 43/111 (38%), Gaps = 6/111 (5%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P + P P V G TA C V+G P P V W + LI + + V I
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNW----YLNGQLIRKSKRF--RVRYDGI 1894
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAP 296
L + + + D G TA N G++ L + QRE R P P
Sbjct: 1895 HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEP 1945
Score = 39.3 bits (90), Expect = 0.009
Identities = 30/129 (23%), Positives = 49/129 (37%), Gaps = 7/129 (5%)
Query: 163 WPPSSPGPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQ 222
W S G P P +PP+ + + V T +V G P P V W
Sbjct: 5162 WRSDSFGTPNEAIEPKDNE--MPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKW--- 5216
Query: 223 SHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQ 282
R ++ PD+ V ++ L + N + + G Y C A N G ++ + ++
Sbjct: 5217 --YRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMP 5274
Query: 283 REPARDAAP 291
+E A P
Sbjct: 5275 QEERVVALP 5283
Score = 37.4 bits (85), Expect = 0.036
Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 6/96 (6%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PPA+ + G A C VSG V+W + + ++P + +
Sbjct: 3344 PPAIITPLQDTVTSEGQPARFQCRVSGTDLK-VSWYSKDKK-----IKPSRFFRMTQFED 3397
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
QL + A PED G YT A NA G + + LS+
Sbjct: 3398 TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433
Score = 37.0 bits (84), Expect = 0.047
Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 8/100 (8%)
Query: 173 TTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMR 232
T + PG P P + P Q + GG+ C V G P P V W+K + +
Sbjct: 1070 TEEQAGPGE-PAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK-----SGVPLT 1123
Query: 233 PDQMYGNVVVTSIGQ--LVLYNARPEDAGLYTCTARNAAG 270
Y G+ LV+ +DAG YT RN G
Sbjct: 1124 TGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG 1163
Score = 35.0 bits (79), Expect = 0.18
Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 5/102 (4%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN 228
G +TA A PP V+ G L V+G P P V + + + ++
Sbjct: 87 GQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS 146
Query: 229 LIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+ G++ L++ A PED+G Y+ A N+ G
Sbjct: 147 SLDFQISQEGDLY-----SLLIAEAYPEDSGTYSVNATNSVG 183
Score = 35.0 bits (79), Expect = 0.18
Identities = 25/113 (22%), Positives = 44/113 (38%), Gaps = 11/113 (9%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW---EKQSHQRENLIMRPDQMYGNVV 241
PP+ Q V G + + C G P P VTW + + +N I+ + Y +
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILT 4002
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIP 294
++S+ ++ G TC N G ++ L V ++ A +P
Sbjct: 4003 LSSV--------HHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHKVP 4047
Score = 33.9 bits (76), Expect = 0.40
Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 200 GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAG 259
G + HC +SG P P + W K + I ++ + + L + PED G
Sbjct: 1305 GMGVTFHCKMSGYPLPKIAWYKDGKR----IKHGERYQMDFLQDGRASLRIPVVLPEDEG 1360
Query: 260 LYTCTARNAAG 270
+YT A N G
Sbjct: 1361 IYTAFASNIKG 1371
Score = 33.9 bits (76), Expect = 0.40
Identities = 24/90 (26%), Positives = 33/90 (36%), Gaps = 11/90 (12%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQS---HQRENLIMRPDQMYGNVV 241
PP S +G A C V G P P V W K R + + N+
Sbjct: 5513 PPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLF 5572
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGL 271
+TS+ + D G Y C A N +G+
Sbjct: 5573 ITSLVK--------SDEGEYRCVATNKSGM 5594
Score = 33.1 bits (74), Expect = 0.67
Identities = 24/73 (32%), Positives = 30/73 (41%), Gaps = 8/73 (10%)
Query: 200 GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIG--QLVLYNARPED 257
G TA V GRP P W Q N VV+ G L++ A P D
Sbjct: 1471 GQTARFDLKVVGRPMPETFWFHDGQQIVN------DYTHKVVIKEDGTQSLIIVPATPSD 1524
Query: 258 AGLYTCTARNAAG 270
+G +T A+N AG
Sbjct: 1525 SGEWTVVAQNRAG 1537
Score = 33.1 bits (74), Expect = 0.67
Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 4/85 (4%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P ++ Q V G A V G+P P W K + I R D++Y ++
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVK----IERSDRIYWYWPEDNV 2133
Query: 246 GQLVLYNARPEDAGLYTCTARNAAG 270
+LV+ + ED+ A N AG
Sbjct: 2134 CELVIRDVTAEDSASIMVKAINIAG 2158
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 59.7 bits (143), Expect = 7e-09
Identities = 27/86 (31%), Positives = 38/86 (44%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP P Q V +G T + C+ +G P PA+ W ++ Q +P Q V+
Sbjct: 311 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ 370
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG 270
G L + N + D G Y C N AG
Sbjct: 371 TGDLTITNVQRSDVGYYICQTLNVAG 396
Score = 46.2 bits (108), Expect = 8e-05
Identities = 40/137 (29%), Positives = 54/137 (39%), Gaps = 30/137 (21%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + PS V G A+L+C GRP P + W K + E D + ++
Sbjct: 28 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVET---DKDDPRSHRMLLP 84
Query: 245 IGQLVLY------NARPEDAGLYTCTARNAAG------------LLRADFPLSVVQREPA 286
G L +RP D G+Y C ARN G +LR DF R+
Sbjct: 85 SGSLFFLRIVHGRKSRP-DEGVYVCVARNYLGEAVSHNASLEVAILRDDF------RQNP 137
Query: 287 RDAAPSI--PAPAECLP 301
D ++ PA EC P
Sbjct: 138 SDVMVAVGEPAVMECQP 154
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/123 (28%), Positives = 47/123 (38%), Gaps = 11/123 (8%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + P Q V V GT L C +G P P + W K R Q+
Sbjct: 415 PPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLEN------ 468
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV----VQREPARDAAPSIPAPAECL 300
G L + A+ D G YTC A +G + V V +P R P++ A
Sbjct: 469 -GVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSK 527
Query: 301 PDV 303
P+V
Sbjct: 528 PEV 530
Score = 42.0 bits (97), Expect = 0.001
Identities = 57/219 (26%), Positives = 80/219 (36%), Gaps = 23/219 (10%)
Query: 71 GLHSCVAARFPGSPAAPTTAASCEGFVCP----QQGSDCDIWDGQP-VCRCRD-RCEKEP 124
G++ CVA + G A + AS E + Q SD + G+P V C+ R EP
Sbjct: 104 GVYVCVARNYLGE--AVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEP 161
Query: 125 SFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPGAAPV 184
+ + DG ++ D +RG L I + + G R + A
Sbjct: 162 TISWKKDGSPLDDK---DERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELT 218
Query: 185 P---PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV 241
P+ PS AV V +A C+ G P P V W K + P Y
Sbjct: 219 VLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGE------LPKSRY---E 269
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
+ L + D G YTC A N G A L+V
Sbjct: 270 IRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Score = 38.9 bits (89), Expect = 0.012
Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 9/103 (8%)
Query: 191 SPSPQAVQVGGTASLHCDVS-GRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLV 249
+PS V VG A + C G P P ++W+K ++ R + G+L+
Sbjct: 136 NPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLM 187
Query: 250 LYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPS 292
+ R DAG Y C N G ++ V P+ PS
Sbjct: 188 ITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPS 230
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 59.7 bits (143), Expect = 7e-09
Identities = 38/110 (34%), Positives = 55/110 (50%), Gaps = 6/110 (5%)
Query: 172 ETTARPTPGAAPV-PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLI 230
ET P P PV PP L S V G + +L C +SG P P VTW ++ +Q E+ I
Sbjct: 928 ETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSI 987
Query: 231 MRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
+ + I +L++ A ED+G +TC+A N AG + L+V
Sbjct: 988 -----DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 52.4 bits (124), Expect = 1e-06
Identities = 37/124 (29%), Positives = 51/124 (41%), Gaps = 21/124 (16%)
Query: 182 APVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN----LIMRPDQMY 237
AP PP + P VQ G A +SGRP P ++W K+ + Q Y
Sbjct: 3235 APEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3294
Query: 238 GNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPA 297
L+L A PEDA +YTC A+N G+ LSV P + +P
Sbjct: 3295 ---------TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV--------EVPEVVSPD 3337
Query: 298 ECLP 301
+ +P
Sbjct: 3338 QEMP 3341
Score = 51.2 bits (121), Expect = 2e-06
Identities = 37/146 (25%), Positives = 57/146 (39%), Gaps = 22/146 (15%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP + P VG + SL C V+G P V+W K + +RP Y +
Sbjct: 6078 PPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTK-----LRPTPEYRTYFTNN 6132
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQ 304
+ LV D+G YTC A N+ G + + +R+ P+ A L D++
Sbjct: 6133 VATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLP-------PSFARQLKDIE 6185
Query: 305 ACTG----------PTSPHLVLWHYD 320
G ++P V W+ D
Sbjct: 6186 QTVGLPVTLTCRLNGSAPIQVCWYRD 6211
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 13/123 (10%)
Query: 164 PPSSPGPPETTARPTPGAAPVPPALYSSPSPQA---VQVGGTASLHCDVSGRPPPAVTWE 220
PPS P P T A VPP + S + ++ V+ G L V G+P P V+W+
Sbjct: 19276 PPSEPSDPVTIL-----AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWK 19330
Query: 221 KQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
K + +++P + + ++ L L++ +D+G YT TA N++G A L V
Sbjct: 19331 K-----DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 19385
Query: 281 VQR 283
+ +
Sbjct: 19386 LDK 19388
Score = 49.3 bits (116), Expect = 9e-06
Identities = 36/124 (29%), Positives = 53/124 (42%), Gaps = 12/124 (9%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP P V VG +ASL C ++G P V+W K + +RP Y +
Sbjct: 7960 PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTK-----LRPTTTYKMHFRNN 8014
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQ 304
+ LV D+G Y C A N+ G + A L+V +++ P+ + L DVQ
Sbjct: 8015 VATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLP-------PSFSRQLRDVQ 8067
Query: 305 ACTG 308
G
Sbjct: 8068 ETVG 8071
Score = 48.9 bits (115), Expect = 1e-05
Identities = 41/155 (26%), Positives = 61/155 (39%), Gaps = 10/155 (6%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN 228
G ++A+ VPP P + +G + + C V+G P +TW K + +
Sbjct: 7195 GTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNRE--- 7251
Query: 229 LIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPAR- 287
+RP Y +V + L + DAG YTC A N AG L V +EP R
Sbjct: 7252 --IRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGV--QEPPRF 7307
Query: 288 --DAAPSIPAPAECLPDVQACTGPTSPHLVLWHYD 320
PS + + G + VLW+ D
Sbjct: 7308 IKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKD 7342
Score = 47.4 bits (111), Expect = 3e-05
Identities = 32/108 (29%), Positives = 48/108 (44%), Gaps = 13/108 (12%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT-- 243
PA S P Q + G C++SG P P + W K + P + NV ++
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNN--------LPISISSNVSISRS 33185
Query: 244 -SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQ--REPARD 288
++ L + NA D+G YT A+N G A L V+ EP+R+
Sbjct: 33186 RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSRE 33233
Score = 46.6 bits (109), Expect = 6e-05
Identities = 38/137 (27%), Positives = 55/137 (40%), Gaps = 12/137 (8%)
Query: 185 PPALYSSPSPQAV-QVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
PP PSP V + G + + C ++G P V+W ++ + Q +G +
Sbjct: 4860 PPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAI-----QKHGISFID 4914
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDV 303
+ + AR E++G Y C ARN AG L V +EP P DV
Sbjct: 4915 GLATFQISGARVENSGTYVCEARNDAGTASCSIELKV--KEPPTFIRELKPVEVVKYSDV 4972
Query: 304 Q---ACTGPTSPHLVLW 317
+ TG T P V W
Sbjct: 4973 ELECEVTG-TPPFEVTW 4988
Score = 46.2 bits (108), Expect = 8e-05
Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 13/131 (9%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G ++ L C ++G P V W + H+ + Y + S+ + + N E
Sbjct: 5435 VKAGDSSRLECKIAGSPEIRVVWFRNEHE-----LPASDKYRMTFIDSVAVIQMNNLSTE 5489
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQAC----TGPTSP 312
D+G + C A+N AG V+ +EP S P E L + + T P
Sbjct: 5490 DSGDFICEAQNPAG--STSCSTKVIVKEP--PVFSSFPPIVETLKNAEVSLECELSGTPP 5545
Query: 313 HLVLWHYDPQR 323
V+W+ D ++
Sbjct: 5546 FEVVWYKDKRQ 5556
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/122 (30%), Positives = 50/122 (40%), Gaps = 13/122 (10%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN 228
G ++AR T P P V G +A C V+G P +TW K +N
Sbjct: 6254 GTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSK-----DN 6308
Query: 229 LIMRPDQMYGNVVVTSIG---QLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREP 285
+RP GN +T +G L + D+G YTC A N G LSV +EP
Sbjct: 6309 KEIRPG---GNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSV--KEP 6363
Query: 286 AR 287
+
Sbjct: 6364 PK 6365
Score = 45.1 bits (105), Expect = 2e-04
Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 10/96 (10%)
Query: 195 QAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIG-QLVLYNA 253
Q ++VG T L + G P P VTW+K+ R + VT +G +L + NA
Sbjct: 17228 QHIKVGDTLRLSAIIKGVPFPKVTWKKED--------RDAPTKARIDVTPVGSKLEIRNA 17279
Query: 254 RPEDAGLYTCTARNAAGLLRADFPLSVVQRE-PARD 288
ED G+Y+ T N AG + V+ + P RD
Sbjct: 17280 AHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRD 17315
Score = 44.3 bits (103), Expect = 3e-04
Identities = 42/164 (25%), Positives = 61/164 (37%), Gaps = 17/164 (10%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
VPP+ +G + L C VSG P +V W + ++ + NV
Sbjct: 6739 VPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTL 6798
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDV 303
++ L P D G+YTC A N AG L+ VQ P+ + P E LP +
Sbjct: 6799 NLSLL-----EPSDTGIYTCVAANVAGSDECSAVLT-VQEPPSFEQTPD---SVEVLPGM 6849
Query: 304 Q----ACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFET 343
+ T P V W +G P C+ + F T
Sbjct: 6850 SLTFTSVIRGTPPFKVKWF----KGSRELVPGESCNISLEDFVT 6889
Score = 44.3 bits (103), Expect = 3e-04
Identities = 61/256 (23%), Positives = 95/256 (37%), Gaps = 25/256 (9%)
Query: 38 SPNLWVD-AQSTCERECSRDQDCAAAEKCCI--NVCGLHSCVAARFPGSPAAPTTAASCE 94
S N+W+ +++ + SR + A + C N G+ C A S P T
Sbjct: 7536 SDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATL---SVLEPATIVEKP 7592
Query: 95 GFVCPQQGSDCDIWDGQPVCRCRDRCEKEPSFTCASDG--LTYYNRCYMDAEACLRGLHL 152
+ G C + C E S DG LT N+ + + GL +
Sbjct: 7593 ESIKVTTGDTCTL-------ECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKI 7645
Query: 153 -HIVPCKH-VLSWPPSSP-GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDV 209
++ P V S+ +P G TA VPP+ G + + C V
Sbjct: 7646 INVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKV 7705
Query: 210 SGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAA 269
G PP +V+W + ++ + + Y + + L + D+G YTC A N A
Sbjct: 7706 YGSPPISVSWFHEGNE-----ISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMA 7760
Query: 270 GLLRADFPLSVVQREP 285
G PL+V REP
Sbjct: 7761 GSDECSAPLTV--REP 7774
Score = 43.9 bits (102), Expect = 4e-04
Identities = 29/122 (23%), Positives = 53/122 (43%), Gaps = 11/122 (9%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP+ + +A+ V+G PP ++TW K + ++ D +Y + V S
Sbjct: 5047 PPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKD----DQILDEDDNVYISFV-DS 5101
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGL------LRADFPLSVVQREPARDAAPSIPAPAE 298
+ L + + +G YTC A+N +G+ L P +V++ + D P E
Sbjct: 5102 VATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLE 5161
Query: 299 CL 300
C+
Sbjct: 5162 CV 5163
Score = 43.5 bits (101), Expect = 5e-04
Identities = 32/111 (28%), Positives = 43/111 (38%), Gaps = 6/111 (5%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P + P P V G TA C V+G P P V W + LI + + V I
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNW----YLNGQLIRKSKRF--RVRYDGI 1894
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAP 296
L + + + D G TA N G++ L + QRE R P P
Sbjct: 1895 HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEP 1945
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/86 (32%), Positives = 34/86 (39%), Gaps = 5/86 (5%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP PSP G L C++SG PP V W K Q N + ++ TS
Sbjct: 6457 PPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRN--SKKFKITSKHFDTS 6514
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG 270
L + N D G Y C A N G
Sbjct: 6515 ---LHILNLEASDVGEYHCKATNEVG 6537
Score = 43.5 bits (101), Expect = 5e-04
Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 5/86 (5%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP+ P P V G + V G PP +V+W K S + + P + S
Sbjct: 7774 PPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSE-----LVPGDRCNVSLEDS 7828
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG 270
+ +L L++ +G YTC N AG
Sbjct: 7829 VAELELFDVDTSQSGEYTCIVSNEAG 7854
Score = 43.5 bits (101), Expect = 5e-04
Identities = 37/129 (28%), Positives = 50/129 (38%), Gaps = 18/129 (13%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
++ G L DVSGRPPP + W K + E + + LV ++
Sbjct: 21473 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIK-----IADFSTNLVNKDSTRR 21527
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACTGPTSPHLVL 316
D+G YT TA N G + F + V+ R P P E A T TS VL
Sbjct: 21528 DSGAYTLTATNPGGFAKHIFNVKVLDR----------PGPPE---GPLAVTEVTSEKCVL 21574
Query: 317 WHYDPQRGG 325
+ P G
Sbjct: 21575 SWFPPLDDG 21583
Score = 42.7 bits (99), Expect = 9e-04
Identities = 37/139 (26%), Positives = 56/139 (40%), Gaps = 16/139 (11%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQA---VQVGGTASLHCDVSGRPPPAVTWEKQSHQ 225
GPP T T PPA+ S + + G T + V+GRP P W K+ +
Sbjct: 15085 GPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGE 15144
Query: 226 RENLIMRPDQMYGNVVVTSIG---QLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQ 282
+ VV+ ++G +L++ +A +D G Y TA N+ G A + V
Sbjct: 15145 LDK---------DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFD 15195
Query: 283 -REPARDAAPSIPAPAECL 300
P D P + CL
Sbjct: 15196 VPGPVLDLKPVVTNRKMCL 15214
Score = 42.7 bits (99), Expect = 9e-04
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 9/75 (12%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQS-HQRENLIMRPDQMYGNVVVTSIGQLVLYNARP 255
++ G + L VSGRPPP +TW KQ I+ + Y ++V + +
Sbjct: 29458 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY------- 29510
Query: 256 EDAGLYTCTARNAAG 270
DAG YT A N +G
Sbjct: 29511 -DAGKYTIEAENQSG 29524
Score = 42.4 bits (98), Expect = 0.001
Identities = 35/138 (25%), Positives = 49/138 (35%), Gaps = 5/138 (3%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP+ + GGTA+ + G P VTW K S + + D +
Sbjct: 4485 PPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDE-----ITEDDNIRMTFENN 4539
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQ 304
+ L L + G Y C A+N AG+ R LSV + + A SI +Q
Sbjct: 4540 VASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQ 4599
Query: 305 ACTGPTSPHLVLWHYDPQ 322
T W D Q
Sbjct: 4600 VKFSGTKEITAKWFKDGQ 4617
Score = 42.4 bits (98), Expect = 0.001
Identities = 40/151 (26%), Positives = 57/151 (37%), Gaps = 11/151 (7%)
Query: 170 PPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENL 229
P +T+ T PP S P SL C++SG PP V W K Q
Sbjct: 5501 PAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQ---- 5556
Query: 230 IMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQ-REPARD 288
+R + Y + + N D G Y C A+N G +D + V+ +EP R
Sbjct: 5557 -LRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG---SDTCVCTVKLKEPPRF 5612
Query: 289 AAP--SIPAPAECLPDVQACTGPTSPHLVLW 317
+ S+ A ++QA P V W
Sbjct: 5613 VSKLNSLTVVAGEPAELQASIEGAQPIFVQW 5643
Score = 42.4 bits (98), Expect = 0.001
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 5/86 (5%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
P + P V VG T +L C V+G P +V W K + ++ Q +
Sbjct: 5703 PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYK-----DGKLLTSSQKHKFSFYNK 5757
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG 270
I L + + +DAG YT +N G
Sbjct: 5758 ISSLRILSVERQDAGTYTFQVQNNVG 5783
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/128 (22%), Positives = 47/128 (36%), Gaps = 5/128 (3%)
Query: 188 LYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQ 247
+ + P V G +A CD G P P VTW R+ ++ +
Sbjct: 32563 ILTKPRSMTVYEGESARFSCDTDGEPVPTVTW-----LRKGQVLSTSARHQVTTTKYKST 32617
Query: 248 LVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACT 307
+ + + D G Y+ N+ G A+F L++ + A S P P V++
Sbjct: 32618 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPE 32677
Query: 308 GPTSPHLV 315
SP V
Sbjct: 32678 AVKSPKRV 32685
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/143 (23%), Positives = 54/143 (37%), Gaps = 17/143 (11%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+PP+ G L C V+G P ++ W K + + N
Sbjct: 4673 IPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFL 4732
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV------VQREPARDAAPSIPAPA 297
I QL D+G YTC+A N AG + L+V V++ ++D P+
Sbjct: 4733 EISQL-----EGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRV-- 4785
Query: 298 ECLPDVQACTGPTSPHLVLWHYD 320
++A G T+P + W D
Sbjct: 4786 ----QLKALVGGTAPMTIKWFKD 4804
Score = 41.6 bits (96), Expect = 0.002
Identities = 25/86 (29%), Positives = 33/86 (38%), Gaps = 5/86 (5%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP P V L C+V+G PP VTW K + + +R + Y S
Sbjct: 4954 PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNRE-----IRSSKKYTLTDRVS 5008
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG 270
+ L + P D G Y C N G
Sbjct: 5009 VFNLHITKCDPSDTGEYQCIVSNEGG 5034
Score = 41.6 bits (96), Expect = 0.002
Identities = 32/117 (27%), Positives = 47/117 (40%), Gaps = 6/117 (5%)
Query: 171 PETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW----EKQSHQR 226
P T P P P V+ G ++ + G P P +TW K+ +
Sbjct: 16102 PSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNK 16161
Query: 227 ENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
E ++ D +VV LV+ +R D GLYT TA N G + L+V+ R
Sbjct: 16162 EPVLY--DTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGR 16216
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 7/84 (8%)
Query: 185 PPALYSSP-SPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
PP ++ P Q V+ G TA L C+VS R V W K + + + Y V
Sbjct: 12283 PPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTE-----ILKSKKYEIVADG 12336
Query: 244 SIGQLVLYNARPEDAGLYTCTARN 267
+ +LV+++ PED YTC A++
Sbjct: 12337 RVRKLVIHDCTPEDIKTYTCDAKD 12360
Score = 41.2 bits (95), Expect = 0.002
Identities = 38/149 (25%), Positives = 59/149 (39%), Gaps = 27/149 (18%)
Query: 184 VPPALYSSPS---PQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNV 240
VPP + P ++ G + + V GRP P VTW K + E + N+
Sbjct: 27954 VPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM--------NM 28005
Query: 241 VVTSI---GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPA 297
+T + L + +A + G+YT A+NA+G +A+ + VQ P + P
Sbjct: 28006 EITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVK-VQDTPGKVVGPI----- 28059
Query: 298 ECLPDVQACTGPTSPHLVLWHYDPQRGGC 326
T T + LW P GC
Sbjct: 28060 -------RFTNITGEKMTLWWDAPLNDGC 28081
Score = 40.4 bits (93), Expect = 0.004
Identities = 38/147 (25%), Positives = 53/147 (36%), Gaps = 13/147 (8%)
Query: 150 LHLHIVPCKHVLSWPPSSPGPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDV 209
L +V C + G TA T A PP S P VG A C V
Sbjct: 3516 LRTQVVDCGEYTCKASNEYGSVSCTATLTVTEA-YPPTFLSRPKSLTTFVGKAAKFICTV 3574
Query: 210 SGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAA 269
+G P W Q++ + P + + L L N +D G+Y+C A N
Sbjct: 3575 TGTPVIETIW-----QKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKF 3629
Query: 270 G-------LLRADFPLSVVQREPARDA 289
G L+ D P + + EP + A
Sbjct: 3630 GADICQAELIIIDKPHFIKELEPVQSA 3656
Score = 40.4 bits (93), Expect = 0.004
Identities = 30/106 (28%), Positives = 42/106 (39%), Gaps = 10/106 (9%)
Query: 199 VGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDA 258
V GT L C ++G P V+W K + + Y V L + DA
Sbjct: 4126 VNGTCRLDCKIAGSLPMRVSWFKDGKE-----IAASDRYRIAFVEGTASLEIIRVDMNDA 4180
Query: 259 GLYTCTARNAAGLLRADFPLSVVQREPARDAAPS----IPAPAECL 300
G +TC A N+ G + L +VQ P+ P +P A CL
Sbjct: 4181 GNFTCRATNSVGSKDSSGAL-IVQEPPSFVTKPGSKDVLPGSAVCL 4225
Score = 40.4 bits (93), Expect = 0.004
Identities = 33/118 (27%), Positives = 47/118 (39%), Gaps = 13/118 (11%)
Query: 207 CDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTAR 266
C + G P V W K + ++ + V S+ L ++N ED+G YTC A
Sbjct: 7327 CKIGGSPEIKVLWYKDETE-----IQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAH 7381
Query: 267 NAAGLLRADFPLSVVQREPARDAAPSIPAPAECLP----DVQACTGPTSPHLVLWHYD 320
NAAG + L V + R P P E L ++ T P V W+ D
Sbjct: 7382 NAAGSASSSTSLKVKEPPIFRKK----PHPIETLKGADVHLECELQGTPPFHVSWYKD 7435
Score = 40.4 bits (93), Expect = 0.004
Identities = 23/86 (26%), Positives = 33/86 (38%), Gaps = 5/86 (5%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP P P G L C++ G PP V+W K + +R + Y +
Sbjct: 7398 PPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRE-----LRSGKKYKIMSENF 7452
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG 270
+ + + N D G Y C A N G
Sbjct: 7453 LTSIHILNVDAADIGEYQCKATNDVG 7478
Score = 40.4 bits (93), Expect = 0.004
Identities = 23/94 (24%), Positives = 42/94 (44%), Gaps = 9/94 (9%)
Query: 180 GAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWE---KQSHQRENLIMRPDQM 236
G +PP + + PS ++ G ++ C +G P P VTW ++ H +E +
Sbjct: 33323 GIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIEN- 33381
Query: 237 YGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+ L++ + + +D GLYT + N G
Sbjct: 33382 -----TDDLTTLIIMDVQKQDGGLYTLSLGNEFG 33410
Score = 40.0 bits (92), Expect = 0.006
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 5/86 (5%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP+ + P + G A L C+VSG P ++W K Q +R + Y S
Sbjct: 3830 PPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQ-----IRSSKKYRLFSQKS 3884
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG 270
+ L +++ D G Y C N G
Sbjct: 3885 LVCLEIFSFNSADVGEYECVVANEVG 3910
Score = 40.0 bits (92), Expect = 0.006
Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 6/102 (5%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP S + V G A L + G P V W K+ + ++R + V +
Sbjct: 5609 PPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEE----VIRESENIRITFVEN 5664
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPA 286
+ L A P +AG Y C +N G+ L V+ EPA
Sbjct: 5665 VATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVL--EPA 5704
Score = 40.0 bits (92), Expect = 0.006
Identities = 35/123 (28%), Positives = 48/123 (39%), Gaps = 9/123 (7%)
Query: 200 GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAG 259
G + L C +SG P V+W + + + Y + S+ L + A ED+G
Sbjct: 6379 GESIQLECKISGSPEIKVSWFRNDSE-----LHESWKYNMSFINSVALLTINEASAEDSG 6433
Query: 260 LYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDV--QACTGPTSPHLVLW 317
Y C A N G L+ V+ P PS P A DV Q T P V+W
Sbjct: 6434 DYICEAHNGVGDASCSTALT-VKAPPVFTQKPS-PVGALKGSDVILQCEISGTPPFEVVW 6491
Query: 318 HYD 320
D
Sbjct: 6492 VKD 6494
Score = 40.0 bits (92), Expect = 0.006
Identities = 31/106 (29%), Positives = 41/106 (38%), Gaps = 6/106 (5%)
Query: 181 AAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNV 240
A PP S + VG L + G P +V W K + I+R
Sbjct: 7487 ALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGE----IVRESDNIWIS 7542
Query: 241 VVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPA 286
+I L P +AG YTC +N AG+ LSV+ EPA
Sbjct: 7543 YSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVL--EPA 7586
Score = 40.0 bits (92), Expect = 0.006
Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 12/101 (11%)
Query: 174 TARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRP 233
T P P + + P + Q G + VSG PPP + WEK +P
Sbjct: 31783 TLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG--------QP 31834
Query: 234 DQMYGNVVVTSIG----QLVLYNARPEDAGLYTCTARNAAG 270
+ N+ + G L + + PED G Y TA N AG
Sbjct: 31835 LSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAG 31875
Score = 39.7 bits (91), Expect = 0.007
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)
Query: 185 PPALYSSPSPQAVQVGG-TASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
PP+ P + + G +A LHC + G P VTW K + +E +MY V
Sbjct: 3736 PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFK--NNKELSESNTVRMY---FVN 3790
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAG 270
S L + + + ED+G Y+C A N G
Sbjct: 3791 SEAILDITDVKVEDSGSYSCEAVNDVG 3817
Score = 39.7 bits (91), Expect = 0.007
Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 5/86 (5%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
P + P P V G +L C V+G P + W K + + D + +
Sbjct: 6644 PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRE-----LSADSKHHITFINK 6698
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG 270
+ L + A D GLY+ +N+ G
Sbjct: 6699 VASLKIPCAEMSDKGLYSFEVKNSVG 6724
Score = 39.7 bits (91), Expect = 0.007
Identities = 53/230 (23%), Positives = 83/230 (36%), Gaps = 21/230 (9%)
Query: 71 GLHSCVAARFPGSP--AAPTTAASCEGFVCPQQGSDCDIWDGQPVCRCRDRCEKEPSFTC 128
G ++C+A GS +AP T FV Q+ D+ G V + P F+
Sbjct: 7750 GDYTCIATNMAGSDECSAPLTVREPPSFV--QKPDPMDVLTGTNVT-FTSIVKGTPPFSV 7806
Query: 129 A----SDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPGAAPV 184
+ S L +RC + E + L L V + + T
Sbjct: 7807 SWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKA 7866
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
P + +++ G L +G PP +VTW+K + + P Q
Sbjct: 7867 PAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNG-----INVTPSQRCNITTTEK 7921
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG-------LLRADFPLSVVQREPAR 287
L + ++ EDAG Y C NA+G +L + P V Q EP +
Sbjct: 7922 SAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVK 7971
Score = 39.7 bits (91), Expect = 0.007
Identities = 30/115 (26%), Positives = 45/115 (39%), Gaps = 5/115 (4%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN 228
G ++AR PP +P VG +A C V+G P V+W K S +
Sbjct: 8136 GSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSRE--- 8192
Query: 229 LIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
+R Y + + L + D+G YTC A N G L++ +R
Sbjct: 8193 --IRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER 8245
Score = 39.7 bits (91), Expect = 0.007
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 9/75 (12%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQ-RENLIMRPDQMYGNVVVTSIGQLVLYNARP 255
++ GG+ L + GRP P V W K + R+ I+ V +S LVL N
Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIID--------VTSSFTSLVLDNVNR 23005
Query: 256 EDAGLYTCTARNAAG 270
D+G YT T N++G
Sbjct: 23006 YDSGKYTLTLENSSG 23020
Score = 39.3 bits (90), Expect = 0.009
Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 5/86 (5%)
Query: 199 VGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDA 258
+G A+L C V G P ++W K E+ +R Y ++ LV+ D
Sbjct: 7033 IGEPATLQCKVDGTPEIRISWYK-----EHTKLRSAPAYKMQFKNNVASLVINKVDHSDV 7087
Query: 259 GLYTCTARNAAGLLRADFPLSVVQRE 284
G Y+C A N+ G + + L + R+
Sbjct: 7088 GEYSCKADNSVGAVASSAVLVIKARK 7113
Score = 39.3 bits (90), Expect = 0.009
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 9/75 (12%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI-GQLVLYNARP 255
V GG + VSG+PPP VTW N+ R + T+I +V+ N +
Sbjct: 16536 VHAGGVIRIIAYVSGKPPPTVTW--------NMNERTLPQEATIETTAISSSMVIKNCQR 16587
Query: 256 EDAGLYTCTARNAAG 270
G+Y+ A+N AG
Sbjct: 16588 SHQGVYSLLAKNEAG 16602
Score = 38.9 bits (89), Expect = 0.012
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 15/121 (12%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
VPP+ +G + L C V+G P +V W H++ ++ Y
Sbjct: 5798 VPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAW---FHEKTKIV--SGAKYQTTFSD 5852
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSI---PAPAECL 300
++ L L + D G YTC A N AG L+V +EP PS P P E L
Sbjct: 5853 NVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTV--QEP-----PSFVKEPEPLEVL 5905
Query: 301 P 301
P
Sbjct: 5906 P 5906
Score = 38.9 bits (89), Expect = 0.012
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 7/74 (9%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ GG+A +H GRP P +TW ++ + + + Q+ V T QL + N
Sbjct: 24036 VRAGGSARIHIPFKGRPTPEITWSREEGEFTDKV----QIEKGVNYT---QLSIDNCDRN 24088
Query: 257 DAGLYTCTARNAAG 270
DAG Y N++G
Sbjct: 24089 DAGKYILKLENSSG 24102
Score = 38.5 bits (88), Expect = 0.016
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 5/76 (6%)
Query: 195 QAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNAR 254
Q ++ G L C V+G PP +TW + ++ + V S L L +
Sbjct: 4309 QLLKKGDATQLACKVTGTPPIKITWFANDRE-----IKESSKHRMSFVESTAVLRLTDVG 4363
Query: 255 PEDAGLYTCTARNAAG 270
ED+G Y C A+N AG
Sbjct: 4364 IEDSGEYMCEAQNEAG 4379
Score = 38.5 bits (88), Expect = 0.016
Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 7/85 (8%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G + L GRP P W K NL +R D S L + N
Sbjct: 28369 VRAGASIRLFIAYQGRPTPTAVWSKPD---SNLSLRADIH----TTDSFSTLTVENCNRN 28421
Query: 257 DAGLYTCTARNAAGLLRADFPLSVV 281
DAG YT T N +G F + V+
Sbjct: 28422 DAGKYTLTVENNSGSKSITFTVKVL 28446
Score = 38.1 bits (87), Expect = 0.021
Identities = 33/128 (25%), Positives = 52/128 (40%), Gaps = 11/128 (8%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW---EKQSHQ 225
G ET+++ A P Y VG T LH GRP PA+TW +K
Sbjct: 30612 GEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQN 30671
Query: 226 RENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREP 285
EN+ + + Y ++V+ ++ R AG Y N G + A + +Q +P
Sbjct: 30672 SENITIENTEHYTHLVMKNV-------QRKTHAGKYKVQLSNVFGTVDAILDVE-IQDKP 30723
Query: 286 ARDAAPSI 293
+ P +
Sbjct: 30724 DKPTGPIV 30731
Score = 38.1 bits (87), Expect = 0.021
Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 7/103 (6%)
Query: 179 PGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYG 238
P +P L + A++ G S+ SG+P P +TW+K +N + Y
Sbjct: 31022 PAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKGQDLIDN-----NGHYQ 31075
Query: 239 NVVVTSIGQLVLYN-ARPEDAGLYTCTARNAAGLLRADFPLSV 280
+V S LV N +DAG Y A+N G+ + L V
Sbjct: 31076 VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 31118
Score = 37.7 bits (86), Expect = 0.027
Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 9/103 (8%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVV-T 243
PP+ P P V G + + G PP V W + + + +++ D+ N+
Sbjct: 5892 PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARE----LVKGDRC--NIYFED 5945
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPA 286
++ +L L+N +G YTC N AG +A + +EPA
Sbjct: 5946 TVAELELFNIDISQSGEYTCVVSNNAG--QASCTTRLFVKEPA 5986
Score = 37.7 bits (86), Expect = 0.027
Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 6/103 (5%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP S + +G L V G P +V W K + ++R + + +
Sbjct: 6550 PPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGE----VIRESENTRISFIDN 6605
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPAR 287
I L L + ++G Y C +N AG+ L+V+ EPAR
Sbjct: 6606 IATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVL--EPAR 6646
Score = 37.7 bits (86), Expect = 0.027
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 12/113 (10%)
Query: 177 PTPGAAPVPPALYSSPSPQAVQV--GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPD 234
P A V L+ PQ+++V TA+ V G P P V W K ++ N
Sbjct: 8443 PATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLN------ 8496
Query: 235 QMYGNVVVTSIG---QLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQRE 284
G V + G +L + + D+GLY C A N G + ++ L V +R+
Sbjct: 8497 -QGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERK 8548
Score = 37.4 bits (85), Expect = 0.036
Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 6/96 (6%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PPA+ + G A C VSG V+W + + ++P + +
Sbjct: 3344 PPAIITPLQDTVTSEGQPARFQCRVSGTDLK-VSWYSKDKK-----IKPSRFFRMTQFED 3397
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
QL + A PED G YT A NA G + + LS+
Sbjct: 3398 TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433
Score = 37.4 bits (85), Expect = 0.036
Identities = 38/152 (25%), Positives = 56/152 (36%), Gaps = 18/152 (11%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G T L V G+P P V W K + + R ++ + S + L A+
Sbjct: 18213 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATD--LTRSPRVKIDTRADS-SKFSLTKAKRS 18269
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACTGPTSPHLVL 316
D G Y TA N AG A ++V+ + P P L V + + V
Sbjct: 18270 DGGKYVVTATNTAGSFVAYATVNVLDK----------PGPVRNLKIVDVSSDRCT---VC 18316
Query: 317 WHYDPQRGGC--MTFPARGCDGAARGFETYEA 346
W GGC + C+ + TY A
Sbjct: 18317 WDPPEDDGGCEIQNYILEKCETKRMVWSTYSA 18348
Score = 37.0 bits (84), Expect = 0.047
Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 8/100 (8%)
Query: 173 TTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMR 232
T + PG P P + P Q + GG+ C V G P P V W+K + +
Sbjct: 1070 TEEQAGPGE-PAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK-----SGVPLT 1123
Query: 233 PDQMYGNVVVTSIGQ--LVLYNARPEDAGLYTCTARNAAG 270
Y G+ LV+ +DAG YT RN G
Sbjct: 1124 TGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG 1163
Score = 37.0 bits (84), Expect = 0.047
Identities = 32/140 (22%), Positives = 54/140 (38%), Gaps = 8/140 (5%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+PP+ VG +L C ++G P V W R+ +++R D+ V
Sbjct: 6173 LPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCW-----YRDGVLLRDDENLQTSFVD 6227
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV--VQREPARDAAP-SIPAPAECL 300
++ L + +G Y+C+A N G + L+ ++ P D P SI A
Sbjct: 6228 NVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGES 6287
Query: 301 PDVQACTGPTSPHLVLWHYD 320
D + P + W D
Sbjct: 6288 ADFECHVTGAQPMRITWSKD 6307
Score = 37.0 bits (84), Expect = 0.047
Identities = 23/100 (23%), Positives = 39/100 (39%), Gaps = 5/100 (5%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+ P + + S +VQVG + +SGRP P +TW K + L ++
Sbjct: 23228 IEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTK-----DGLPLKQTTRINVTDSL 23282
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
+ L + +D G Y T N G A + + +
Sbjct: 23283 DLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 23322
Score = 36.6 bits (83), Expect = 0.061
Identities = 23/86 (26%), Positives = 31/86 (36%), Gaps = 5/86 (5%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP +P V G L C V G P + W K + ++P +
Sbjct: 8345 PPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGRE-----IKPSDRCSFSFASG 8399
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG 270
L L + D+G Y C A N AG
Sbjct: 8400 TAVLELRDVAKADSGDYVCKASNVAG 8425
Score = 36.6 bits (83), Expect = 0.061
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 6/74 (8%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G L V GRP P VTW K ++R Q+ +V ++ LV+ N+ +
Sbjct: 18618 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDN---VVRKGQV---DLVDTMAFLVIPNSTRD 18671
Query: 257 DAGLYTCTARNAAG 270
D+G Y+ T N AG
Sbjct: 18672 DSGKYSLTLVNPAG 18685
Score = 36.6 bits (83), Expect = 0.061
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 17/105 (16%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQ-LVLYNARP 255
++ G T L+ V GRPPP +TW K N+ +R D++ ++ T L N
Sbjct: 19705 LRAGVTMRLYVPVKGRPPPKITWSK-----PNVNLR-DRIGLDIKSTDFDTFLRCENVNK 19758
Query: 256 EDAGLYTCTARNAAG----------LLRADFPLSVVQREPARDAA 290
DAG Y T N+ G L P++V +E ++D+A
Sbjct: 19759 YDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSA 19803
Score = 36.6 bits (83), Expect = 0.061
Identities = 28/104 (26%), Positives = 39/104 (37%), Gaps = 8/104 (7%)
Query: 170 PPETTARPTPGAAPVPPALYSSPSPQA---VQVGGTASLHCDVSGRPPPAVTWEKQSHQR 226
P ET T V P + S PQ V G L ++GRPPPA +W +
Sbjct: 29720 PRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSK- 29778
Query: 227 ENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+R + T + +L + D G YT +N G
Sbjct: 29779 ----LRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTG 29818
Score = 36.6 bits (83), Expect = 0.061
Identities = 25/88 (28%), Positives = 34/88 (38%), Gaps = 11/88 (12%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW---EKQSHQRENLIMRPDQMYGNVVV 242
P + ++G A L C + GRP P + W K+ Q M D + V
Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 30592
Query: 243 TSIGQLVLYNARPEDAGLYTCTARNAAG 270
+ Q ED G+YTC A N G
Sbjct: 30593 MTEEQ--------EDEGVYTCIATNEVG 30612
Score = 36.6 bits (83), Expect = 0.061
Identities = 33/140 (23%), Positives = 50/140 (35%), Gaps = 15/140 (10%)
Query: 173 TTARPTPGAAPVP----PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSH---Q 225
T R T AP P P + + V A +G P P W K Q
Sbjct: 32835 TVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQ 32894
Query: 226 RENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREP 285
+ D+ G L ++ D+GLYTCT +N+AG + + L++ +
Sbjct: 32895 GGKYKLSEDK--GGFF------LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 32946
Query: 286 ARDAAPSIPAPAECLPDVQA 305
S +E P +A
Sbjct: 32947 TEAQKVSTQKTSEITPQKKA 32966
Score = 36.2 bits (82), Expect = 0.080
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 5/77 (6%)
Query: 205 LHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCT 264
L + G+P P+V+W+K + D L++Y+ + DAG YT T
Sbjct: 20002 LKIPIKGKPAPSVSWKKGEDP-----LATDTRVSVESSAVNTTLIVYDCQKSDAGKYTIT 20056
Query: 265 ARNAAGLLRADFPLSVV 281
+N AG + VV
Sbjct: 20057 LKNVAGTKEGTISIKVV 20073
Score = 35.8 bits (81), Expect = 0.10
Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 13/105 (12%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP+ + P + V G L G P + W K + + + G+ +T
Sbjct: 4205 PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVS--------GGSCYITK 4256
Query: 245 IG---QLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPA 286
L LY + D+G YTC N AG + L V +EPA
Sbjct: 4257 EALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFV--KEPA 4299
Score = 35.4 bits (80), Expect = 0.14
Identities = 28/103 (27%), Positives = 40/103 (38%), Gaps = 7/103 (6%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP G T +L V G P +VTW K ++R D
Sbjct: 3923 PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQE-----VIREDGKIKMSFSNG 3977
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPAR 287
+ L++ + + G YTC A N AG + L V +EPA+
Sbjct: 3978 VAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIV--KEPAK 4018
Score = 35.4 bits (80), Expect = 0.14
Identities = 24/101 (23%), Positives = 44/101 (43%), Gaps = 7/101 (6%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+ P+L + ++Q G + V GRP P ++W K + NV T
Sbjct: 24310 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTR------VNVEET 24363
Query: 244 SIGQLV-LYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
+ ++ + +D G YT TA N+AG + + V+++
Sbjct: 24364 ATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 24404
Score = 35.0 bits (79), Expect = 0.18
Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 5/102 (4%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN 228
G +TA A PP V+ G L V+G P P V + + + ++
Sbjct: 87 GQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS 146
Query: 229 LIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+ G++ L++ A PED+G Y+ A N+ G
Sbjct: 147 SLDFQISQEGDLY-----SLLIAEAYPEDSGTYSVNATNSVG 183
Score = 35.0 bits (79), Expect = 0.18
Identities = 27/100 (27%), Positives = 37/100 (37%), Gaps = 7/100 (7%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P P + L C V VTW K + + P + Y I
Sbjct: 3644 PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQK-----LPPGKDYKICFEDKI 3698
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREP 285
L + A+ +D+G Y CTA N AG + +V REP
Sbjct: 3699 ATLEIPLAKLKDSGTYVCTASNEAG--SSSCSATVTVREP 3736
Score = 35.0 bits (79), Expect = 0.18
Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G L V+G+P P +TW K ++I++ D+ V + + +++
Sbjct: 13702 VKAGTKIELPATVTGKPEPKITWTK-----ADMILKQDKRITIENVPKKSTVTIVDSKRS 13756
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQR 283
D G Y A N G A ++V+ +
Sbjct: 13757 DTGTYIIEAVNVCGRATAVVEVNVLDK 13783
Score = 34.7 bits (78), Expect = 0.23
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 5/66 (7%)
Query: 205 LHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCT 264
L +V+G PP +TW K +N I+R + Y + + L + DAG Y C
Sbjct: 4412 LLAEVAGTPPFEITWFK-----DNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCR 4466
Query: 265 ARNAAG 270
N G
Sbjct: 4467 VTNEVG 4472
Score = 34.7 bits (78), Expect = 0.23
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPD---QMYGNVVVTSIG--QLVLY 251
V+ G + DV+G P P + W K E +I +P Q+ V S +L +
Sbjct: 15410 VKAGEPVHIPADVTGLPMPKIEWSK----NETVIEKPTDALQITKEEVSRSEAKTELSIP 15465
Query: 252 NARPEDAGLYTCTARNAAGLLRADFPLSVVQR-EPARDAA 290
A ED G YT TA N G + + + V R P R+ A
Sbjct: 15466 KAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 15505
Score = 34.7 bits (78), Expect = 0.23
Identities = 32/142 (22%), Positives = 58/142 (40%), Gaps = 18/142 (12%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+PP + P ++ G + V G+P P W+K E+ ++ + + +
Sbjct: 18898 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKK----GEDEVVTSSHLAVHKADS 18952
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDV 303
S L++ + +D+G Y+ TA N++G + V+ AP P P + D+
Sbjct: 18953 S-SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMD-------APGPPQPPFDISDI 19004
Query: 304 QACTGPTSPHLVLWHYDPQRGG 325
A S WH + GG
Sbjct: 19005 DADACSLS-----WHIPLEDGG 19021
Score = 34.7 bits (78), Expect = 0.23
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 7/74 (9%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
++ T L + GRP P V WEK E ++ Q+ V +S LV+ N
Sbjct: 25119 LRASATLRLFVTIKGRPEPEVKWEK----AEGILTDRAQI---EVTSSFTMLVIDNVTRF 25171
Query: 257 DAGLYTCTARNAAG 270
D+G Y T N +G
Sbjct: 25172 DSGRYNLTLENNSG 25185
Score = 34.7 bits (78), Expect = 0.23
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 7/86 (8%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQ--RENLIMRPDQMYGNVVVTSIGQLVLYNAR 254
V+ A+L C V+G P P V W +Q + + L R + G QL++ +
Sbjct: 30939 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKG-----GYHQLIIASVT 30993
Query: 255 PEDAGLYTCTARNAAGLLRADFPLSV 280
+DA +Y A N G + L V
Sbjct: 30994 DDDATVYQVRATNQGGSVSGTASLEV 31019
Score = 33.9 bits (76), Expect = 0.40
Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 200 GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAG 259
G + HC +SG P P + W K + I ++ + + L + PED G
Sbjct: 1305 GMGVTFHCKMSGYPLPKIAWYKDGKR----IKHGERYQMDFLQDGRASLRIPVVLPEDEG 1360
Query: 260 LYTCTARNAAG 270
+YT A N G
Sbjct: 1361 IYTAFASNIKG 1371
Score = 33.9 bits (76), Expect = 0.40
Identities = 32/143 (22%), Positives = 50/143 (34%), Gaps = 17/143 (11%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+PP+ + +G + + C VSG P + W K + + Y V
Sbjct: 5235 IPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKE-----ISTSAKYRLVCHE 5289
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAA------GLLRADFPLSVVQREPARDAAPSIPAPA 297
L + N ED YTC N A G+L P S + + + A P
Sbjct: 5290 RSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIP------ 5343
Query: 298 ECLPDVQACTGPTSPHLVLWHYD 320
+ + +A T P + W D
Sbjct: 5344 DSTVEFKAILKGTPPFKIKWFKD 5366
Score = 33.9 bits (76), Expect = 0.40
Identities = 23/86 (26%), Positives = 34/86 (39%), Gaps = 5/86 (5%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
P A S +V+ G + L +G P +VTW+K + + V
Sbjct: 5985 PAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFN-----ITTSEKCNIVTTEK 6039
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG 270
L + N+ DAG Y+C N AG
Sbjct: 6040 TCILEILNSTKRDAGQYSCEIENEAG 6065
Score = 33.9 bits (76), Expect = 0.40
Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+VG T + V GRP P +TW K E ++ ++ + +L + A
Sbjct: 17920 VRVGQTIRILARVKGRPEPDITWTK-----EGKVLVREKRVDLIQDLPRVELQIKEAVRA 17974
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQR 283
D G Y +A+N++G + ++V+ R
Sbjct: 17975 DHGKYIISAKNSSGHAQGSAIVNVLDR 18001
Score = 33.9 bits (76), Expect = 0.40
Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 5/87 (5%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+PPA + V G + GRP PAVTW K +N+ ++
Sbjct: 22146 IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHK-----DNVPLKQTTRVNAESTE 22200
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAG 270
+ L + +A ED G Y N+AG
Sbjct: 22201 NNSLLTIKDACREDVGHYVVKLTNSAG 22227
Score = 33.5 bits (75), Expect = 0.52
Identities = 38/153 (24%), Positives = 57/153 (37%), Gaps = 8/153 (5%)
Query: 136 YNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPGAAPVPPALYSSPSPQ 195
Y Y++ A L L + + + G TA+ +PP+ S
Sbjct: 8199 YQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSET 8258
Query: 196 AVQVGGTA-SLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNAR 254
+ G + L V+G P V W K N+ ++P + L + A
Sbjct: 8259 VEETEGNSFKLEGRVAGSQPITVAWYKN-----NIEIQPTSNCEITFKNNTLVLQVRKAG 8313
Query: 255 PEDAGLYTCTARNAAGLLRADFPLSVVQREPAR 287
DAGLYTC N AG A S+V +EP +
Sbjct: 8314 MNDAGLYTCKVSNDAG--SALCTSSIVIKEPKK 8344
Score = 33.1 bits (74), Expect = 0.67
Identities = 24/73 (32%), Positives = 30/73 (41%), Gaps = 8/73 (10%)
Query: 200 GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIG--QLVLYNARPED 257
G TA V GRP P W Q N VV+ G L++ A P D
Sbjct: 1471 GQTARFDLKVVGRPMPETFWFHDGQQIVN------DYTHKVVIKEDGTQSLIIVPATPSD 1524
Query: 258 AGLYTCTARNAAG 270
+G +T A+N AG
Sbjct: 1525 SGEWTVVAQNRAG 1537
Score = 33.1 bits (74), Expect = 0.67
Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 4/85 (4%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P ++ Q V G A V G+P P W K + I R D++Y ++
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVK----IERSDRIYWYWPEDNV 2133
Query: 246 GQLVLYNARPEDAGLYTCTARNAAG 270
+LV+ + ED+ A N AG
Sbjct: 2134 CELVIRDVTAEDSASIMVKAINIAG 2158
Score = 33.1 bits (74), Expect = 0.67
Identities = 18/74 (24%), Positives = 31/74 (41%), Gaps = 5/74 (6%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G ++ D++GRP P ++W K + E N + ++ +
Sbjct: 25801 VKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCI-----RR 25855
Query: 257 DAGLYTCTARNAAG 270
D G Y T +N AG
Sbjct: 25856 DTGQYVLTLKNVAG 25869
Score = 32.7 bits (73), Expect = 0.88
Identities = 32/123 (26%), Positives = 48/123 (39%), Gaps = 9/123 (7%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP P Q V L V G P + W K + + + R ++ + TS
Sbjct: 4767 PPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAAR--SVWKDDTSTS 4824
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQ 304
L L+ A+ D+G Y C N G + L V +EP + P+P L + Q
Sbjct: 4825 ---LELFAAKATDSGTYICQLSNDVGTATSKATLFV--KEPPQFIKK--PSPVLVLRNGQ 4877
Query: 305 ACT 307
+ T
Sbjct: 4878 STT 4880
Score = 32.7 bits (73), Expect = 0.88
Identities = 21/87 (24%), Positives = 38/87 (43%), Gaps = 5/87 (5%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G + +SG+P P VT R+ + ++ + + + L +
Sbjct: 26488 VRAGSNLKVDIPISGKPLPKVTL-----SRDGVPLKATMRFNTEITAENLTINLKESVTA 26542
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQR 283
DAG Y TA N++G +A + V+ R
Sbjct: 26543 DAGRYEITAANSSGTTKAFINIVVLDR 26569
Score = 32.3 bits (72), Expect = 1.1
Identities = 26/100 (26%), Positives = 37/100 (37%), Gaps = 9/100 (9%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V G A+L V+G P W K + + Y ++ QL Y+A
Sbjct: 4028 VTAGDPATLEYTVAGTPELKPKWYKDGRP-----LVASKKYRISFKNNVAQLKFYSAELH 4082
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAP 296
D+G YT N G + +V+ RD AP P
Sbjct: 4083 DSGQYTFEISNEVGSSSCETTFTVLD----RDIAPFFTKP 4118
Score = 32.3 bits (72), Expect = 1.1
Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 5/73 (6%)
Query: 198 QVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPED 257
+ G + V GRP P VTW+K I++ Q + L + D
Sbjct: 21078 KAGDNIKVEIPVLGRPKPTVTWKKGDQ-----ILKQTQRVNFETTATSTILNINECVRSD 21132
Query: 258 AGLYTCTARNAAG 270
+G Y TARN G
Sbjct: 21133 SGPYPLTARNIVG 21145
Score = 32.3 bits (72), Expect = 1.1
Identities = 29/117 (24%), Positives = 46/117 (39%), Gaps = 8/117 (6%)
Query: 170 PPETTARPTPGAAPVPPALYSSPSPQ---AVQVGGTASLHCDVSGRPPPAVTWEKQSHQR 226
P E+T T PP + P + V G + + D+ G+P P + W K +
Sbjct: 22525 PSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 22584
Query: 227 ENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
N ++ TS L + +A D+G Y A+N AG + V+ R
Sbjct: 22585 SNTARL--EIKSTDFATS---LSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDR 22636
Score = 32.3 bits (72), Expect = 1.1
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 4/87 (4%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V G T L D+ G+P P V W K + E R ++ + T+ LV+ +
Sbjct: 24719 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARM-EIKSTIQKTT---LVVKDCIRT 24774
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQR 283
D G Y N G + V+ R
Sbjct: 24775 DGGQYILKLSNVGGTKSIPITVKVLDR 24801
Score = 32.3 bits (72), Expect = 1.1
Identities = 17/86 (19%), Positives = 38/86 (44%), Gaps = 5/86 (5%)
Query: 198 QVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPED 257
+ G + L +SG+P P + W K + ++ + + T + +++ +A +
Sbjct: 26885 RAGTSVKLRAGISGKPAPTIEWYKDDKE-----LQTNALVCVENTTDLASILIKDADRLN 26939
Query: 258 AGLYTCTARNAAGLLRADFPLSVVQR 283
+G Y RNA G A + ++ +
Sbjct: 26940 SGCYELKLRNAMGSASATIRVQILDK 26965
Score = 32.3 bits (72), Expect = 1.1
Identities = 19/60 (31%), Positives = 21/60 (35%), Gaps = 5/60 (8%)
Query: 211 GRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
GRPPP VTW K + D Y S L + D G Y T N G
Sbjct: 27297 GRPPPTVTWRKDEKN-----LGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 27351
Score = 32.0 bits (71), Expect = 1.5
Identities = 21/104 (20%), Positives = 39/104 (37%), Gaps = 5/104 (4%)
Query: 181 AAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNV 240
A +PP +G + C ++G P V+W K + ++++ D
Sbjct: 7111 ARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYK-----DGVLLKDDANLQTS 7165
Query: 241 VVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQRE 284
V ++ L + G Y C+A N G + L + + E
Sbjct: 7166 FVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE 7209
Score = 32.0 bits (71), Expect = 1.5
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 9/90 (10%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQS-HQRENLIMRPDQMYGNVVVTSIGQLVLYNARP 255
V++G L G+P P+++W K +E+ +R + + L + NA+
Sbjct: 27575 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKIT------LSIKNAKK 27628
Query: 256 EDAGLYTCTARNAAGLLRADFPLSVVQREP 285
E G YT NA + R P++V+ P
Sbjct: 27629 EHGGKYTVILDNA--VCRIAVPITVITLGP 27656
Score = 32.0 bits (71), Expect = 1.5
Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 7/111 (6%)
Query: 160 VLSWPPSSPGPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW 219
V+S S GP P A + L+ ++ G L V G+P P + W
Sbjct: 29024 VISKGSESTGPVTCRDEYAPPKAELDARLHGDLV--TIRAGSDLVLDAAVGGKPEPKIIW 29081
Query: 220 EKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
K + + L + Y T+ V+ D+G YT T +NA+G
Sbjct: 29082 TKGDKELD-LCEKVSLQYTGKRATA----VIKFCDRSDSGKYTLTVKNASG 29127
Score = 32.0 bits (71), Expect = 1.5
Identities = 35/150 (23%), Positives = 50/150 (33%), Gaps = 17/150 (11%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRP---DQMYGNVV 241
PP + VG ++ P P VTW K + ++P D+ Y
Sbjct: 31689 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQK-----IKPGDNDKKYTFES 31743
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAA-----PSIPAP 296
+ QL + + +D YT ARN G L+V P D+ + A
Sbjct: 31744 DKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLAN 31803
Query: 297 AECLPDVQAC----TGPTSPHLVLWHYDPQ 322
AEC C P + W D Q
Sbjct: 31804 AECQEGQSVCFEIRVSGIPPPTLKWEKDGQ 31833
Score = 31.6 bits (70), Expect = 2.0
Identities = 23/103 (22%), Positives = 38/103 (36%), Gaps = 11/103 (10%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEK---QSHQRENLIMRPDQMYGNVVV 242
P + P V +G A C++ P W K + ++ + +R +
Sbjct: 3456 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKY------ 3509
Query: 243 TSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREP 285
I L + + D G YTC A N G + L+V + P
Sbjct: 3510 --ISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYP 3550
Score = 31.6 bits (70), Expect = 2.0
Identities = 24/86 (27%), Positives = 30/86 (34%), Gaps = 5/86 (5%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PP+ P Q T + G PP + W K + L+ P G TS
Sbjct: 5329 PPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVE---LVSGPKCFIGLEGSTS 5385
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAG 270
L LY+ G YTC N G
Sbjct: 5386 F--LNLYSVDASKTGQYTCHVTNDVG 5409
Score = 31.6 bits (70), Expect = 2.0
Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Query: 185 PPALYSSPSPQ-AVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
PP L+ + ++VG +L SG+P P V+W K E ++ D+ +
Sbjct: 16817 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKD----EADVLEDDRTHIKTTPA 16872
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
++ L A+ D+G Y N+ G + ++VV R
Sbjct: 16873 TLA-LEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR 16911
Score = 31.6 bits (70), Expect = 2.0
Identities = 26/103 (25%), Positives = 40/103 (38%), Gaps = 13/103 (12%)
Query: 197 VQVGGTASLHC-DVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARP 255
++ G T L+ + G+P P +W K +RP + + L + A
Sbjct: 20390 IKAGDTIVLNAISILGKPLPKSSWSKAGKD-----IRPSDITQITSTPTSSMLTIKYATR 20444
Query: 256 EDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAE 298
+DAG YT TA N G ++V+ P P P E
Sbjct: 20445 KDAGEYTITATNPFGTKVEHVKVTVLD-------VPGPPGPVE 20480
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/86 (23%), Positives = 35/86 (40%), Gaps = 5/86 (5%)
Query: 198 QVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPED 257
+ G ++ +SGRP P VTW + E + ++ L + ++ D
Sbjct: 28660 KAGSPFTIDVPISGRPAPKVTW-----KLEEMRLKETDRVSITTTKDRTTLTVKDSMRGD 28714
Query: 258 AGLYTCTARNAAGLLRADFPLSVVQR 283
+G Y T N AG+ + V+ R
Sbjct: 28715 SGRYFLTLENTAGVKTFSVTVVVIGR 28740
Score = 30.8 bits (68), Expect = 3.3
Identities = 29/116 (25%), Positives = 41/116 (35%), Gaps = 18/116 (15%)
Query: 211 GRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
GRP V W K + + + VTS+ + A ED G Y N+AG
Sbjct: 25420 GRPQATVNWRKDGQTLKETTRV--NVSSSKTVTSLS---IKEASKEDVGTYELCVSNSAG 25474
Query: 271 LLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACTGPTSPHLVLWHYDPQRGGC 326
+ + V+ R P P P D +C T + W+ GGC
Sbjct: 25475 SITVPITIIVLDR-------PGPPGPIRI--DEVSCDSIT----ISWNPPEYDGGC 25517
Score = 30.4 bits (67), Expect = 4.4
Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 9/75 (12%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT-SIGQLVLYNARP 255
V+ G + + + GRP P VTW K + +N N+ T S L++
Sbjct: 20788 VRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN--------RANIENTESFTLLIIPECNR 20839
Query: 256 EDAGLYTCTARNAAG 270
D G + T N AG
Sbjct: 20840 YDTGKFVMTIENPAG 20854
Score = 30.0 bits (66), Expect = 5.7
Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 13/114 (11%)
Query: 196 AVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLV-LYNAR 254
+V+ G L +G PP +V+W K E LI + ++ ++ +T ++ + +
Sbjct: 6937 SVETGSPIVLEATYTGTPPISVSWIKD----EYLISQSERC--SITMTEKSTILEILEST 6990
Query: 255 PEDAGLYTCTARNAAGLLRADFPLSVVQR----EPAR--DAAPSIPAPAECLPD 302
ED Y+C N AG + +SV++ EP +A PA +C D
Sbjct: 6991 IEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVD 7044
Score = 30.0 bits (66), Expect = 5.7
Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 11/90 (12%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+PP+ VG C +SG P +V+W K +P + NV +
Sbjct: 8055 LPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDG--------KPLKDSPNVQTS 8106
Query: 244 SIGQLVLYNARPED---AGLYTCTARNAAG 270
+ N D AG Y+CTA N G
Sbjct: 8107 FLDNTATLNIFKTDRSLAGQYSCTATNPIG 8136
Score = 29.3 bits (64), Expect = 9.7
Identities = 19/80 (23%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 204 SLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTC 263
+L C V+G P V W K Q + P + + ++ + + +D+G YT
Sbjct: 5159 TLECVVAGTPELKVKWLKDGKQ-----IVPSRYFSMSFENNVASFRIQSVMKQDSGQYTF 5213
Query: 264 TARNAAGLLRADFPLSVVQR 283
N G D L V+ +
Sbjct: 5214 KVENDFGSSSCDAYLRVLDQ 5233
Score = 29.3 bits (64), Expect = 9.7
Identities = 23/91 (25%), Positives = 36/91 (39%), Gaps = 12/91 (13%)
Query: 213 PPPAVTWEKQSHQ---RENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAA 269
P P V+W K + + L M+ D + ++ V + DAG+YT T N
Sbjct: 14414 PVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA--------DAGIYTITLENKL 14465
Query: 270 GLLRADFPLSVVQRE-PARDAAPSIPAPAEC 299
G A + V+ P +D S + C
Sbjct: 14466 GSATASINVKVIGLPGPCKDIKASDITKSSC 14496
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 59.7 bits (143), Expect = 7e-09
Identities = 38/110 (34%), Positives = 55/110 (50%), Gaps = 6/110 (5%)
Query: 172 ETTARPTPGAAPV-PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLI 230
ET P P PV PP L S V G + +L C +SG P P VTW ++ +Q E+ I
Sbjct: 882 ETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSI 941
Query: 231 MRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
+ + I +L++ A ED+G +TC+A N AG + L+V
Sbjct: 942 -----DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 52.4 bits (124), Expect = 1e-06
Identities = 37/124 (29%), Positives = 51/124 (41%), Gaps = 21/124 (16%)
Query: 182 APVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN----LIMRPDQMY 237
AP PP + P VQ G A +SGRP P ++W K+ + Q Y
Sbjct: 3189 APEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3248
Query: 238 GNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPA 297
L+L A PEDA +YTC A+N G+ LSV P + +P
Sbjct: 3249 ---------TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV--------EVPEVVSPD 3291
Query: 298 ECLP 301
+ +P
Sbjct: 3292 QEMP 3295
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 13/123 (10%)
Query: 164 PPSSPGPPETTARPTPGAAPVPPALYSSPSPQA---VQVGGTASLHCDVSGRPPPAVTWE 220
PPS P P T A VPP + S + ++ V+ G L V G+P P V+W+
Sbjct: 12971 PPSEPSDPVTIL-----AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWK 13025
Query: 221 KQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
K + +++P + + ++ L L++ +D+G YT TA N++G A L V
Sbjct: 13026 K-----DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 13080
Query: 281 VQR 283
+ +
Sbjct: 13081 LDK 13083
Score = 47.4 bits (111), Expect = 3e-05
Identities = 32/108 (29%), Positives = 48/108 (44%), Gaps = 13/108 (12%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT-- 243
PA S P Q + G C++SG P P + W K + P + NV ++
Sbjct: 26829 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNN--------LPISISSNVSISRS 26880
Query: 244 -SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQ--REPARD 288
++ L + NA D+G YT A+N G A L V+ EP+R+
Sbjct: 26881 RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSRE 26928
Score = 45.1 bits (105), Expect = 2e-04
Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 10/96 (10%)
Query: 195 QAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIG-QLVLYNA 253
Q ++VG T L + G P P VTW+K+ R + VT +G +L + NA
Sbjct: 10923 QHIKVGDTLRLSAIIKGVPFPKVTWKKED--------RDAPTKARIDVTPVGSKLEIRNA 10974
Query: 254 RPEDAGLYTCTARNAAGLLRADFPLSVVQRE-PARD 288
ED G+Y+ T N AG + V+ + P RD
Sbjct: 10975 AHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRD 11010
Score = 43.5 bits (101), Expect = 5e-04
Identities = 32/111 (28%), Positives = 43/111 (38%), Gaps = 6/111 (5%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P + P P V G TA C V+G P P V W + LI + + V I
Sbjct: 1795 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNW----YLNGQLIRKSKRF--RVRYDGI 1848
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAP 296
L + + + D G TA N G++ L + QRE R P P
Sbjct: 1849 HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEP 1899
Score = 43.5 bits (101), Expect = 5e-04
Identities = 37/129 (28%), Positives = 50/129 (38%), Gaps = 18/129 (13%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
++ G L DVSGRPPP + W K + E + + LV ++
Sbjct: 15168 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIK-----IADFSTNLVNKDSTRR 15222
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACTGPTSPHLVL 316
D+G YT TA N G + F + V+ R P P E A T TS VL
Sbjct: 15223 DSGAYTLTATNPGGFAKHIFNVKVLDR----------PGPPE---GPLAVTEVTSEKCVL 15269
Query: 317 WHYDPQRGG 325
+ P G
Sbjct: 15270 SWFPPLDDG 15278
Score = 42.7 bits (99), Expect = 9e-04
Identities = 37/139 (26%), Positives = 56/139 (40%), Gaps = 16/139 (11%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQA---VQVGGTASLHCDVSGRPPPAVTWEKQSHQ 225
GPP T T PPA+ S + + G T + V+GRP P W K+ +
Sbjct: 8780 GPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGE 8839
Query: 226 RENLIMRPDQMYGNVVVTSIG---QLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQ 282
+ VV+ ++G +L++ +A +D G Y TA N+ G A + V
Sbjct: 8840 LDK---------DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFD 8890
Query: 283 -REPARDAAPSIPAPAECL 300
P D P + CL
Sbjct: 8891 VPGPVLDLKPVVTNRKMCL 8909
Score = 42.7 bits (99), Expect = 9e-04
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 9/75 (12%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQS-HQRENLIMRPDQMYGNVVVTSIGQLVLYNARP 255
++ G + L VSGRPPP +TW KQ I+ + Y ++V + +
Sbjct: 23153 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY------- 23205
Query: 256 EDAGLYTCTARNAAG 270
DAG YT A N +G
Sbjct: 23206 -DAGKYTIEAENQSG 23219
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/128 (22%), Positives = 47/128 (36%), Gaps = 5/128 (3%)
Query: 188 LYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQ 247
+ + P V G +A CD G P P VTW R+ ++ +
Sbjct: 26258 ILTKPRSMTVYEGESARFSCDTDGEPVPTVTW-----LRKGQVLSTSARHQVTTTKYKST 26312
Query: 248 LVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACT 307
+ + + D G Y+ N+ G A+F L++ + A S P P V++
Sbjct: 26313 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPE 26372
Query: 308 GPTSPHLV 315
SP V
Sbjct: 26373 AVKSPKRV 26380
Score = 41.6 bits (96), Expect = 0.002
Identities = 32/117 (27%), Positives = 47/117 (40%), Gaps = 6/117 (5%)
Query: 171 PETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW----EKQSHQR 226
P T P P P V+ G ++ + G P P +TW K+ +
Sbjct: 9797 PSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNK 9856
Query: 227 ENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
E ++ D +VV LV+ +R D GLYT TA N G + L+V+ R
Sbjct: 9857 EPVLY--DTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGR 9911
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 7/84 (8%)
Query: 185 PPALYSSP-SPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
PP ++ P Q V+ G TA L C+VS R V W K + + + Y V
Sbjct: 5978 PPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTE-----ILKSKKYEIVADG 6031
Query: 244 SIGQLVLYNARPEDAGLYTCTARN 267
+ +LV+++ PED YTC A++
Sbjct: 6032 RVRKLVIHDCTPEDIKTYTCDAKD 6055
Score = 41.2 bits (95), Expect = 0.002
Identities = 38/149 (25%), Positives = 59/149 (39%), Gaps = 27/149 (18%)
Query: 184 VPPALYSSPS---PQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNV 240
VPP + P ++ G + + V GRP P VTW K + E + N+
Sbjct: 21649 VPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM--------NM 21700
Query: 241 VVTSI---GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPA 297
+T + L + +A + G+YT A+NA+G +A+ + VQ P + P
Sbjct: 21701 EITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVK-VQDTPGKVVGPI----- 21754
Query: 298 ECLPDVQACTGPTSPHLVLWHYDPQRGGC 326
T T + LW P GC
Sbjct: 21755 -------RFTNITGEKMTLWWDAPLNDGC 21776
Score = 40.4 bits (93), Expect = 0.004
Identities = 23/94 (24%), Positives = 42/94 (44%), Gaps = 9/94 (9%)
Query: 180 GAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWE---KQSHQRENLIMRPDQM 236
G +PP + + PS ++ G ++ C +G P P VTW ++ H +E +
Sbjct: 27018 GIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIEN- 27076
Query: 237 YGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+ L++ + + +D GLYT + N G
Sbjct: 27077 -----TDDLTTLIIMDVQKQDGGLYTLSLGNEFG 27105
Score = 40.0 bits (92), Expect = 0.006
Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 12/101 (11%)
Query: 174 TARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRP 233
T P P + + P + Q G + VSG PPP + WEK +P
Sbjct: 25478 TLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG--------QP 25529
Query: 234 DQMYGNVVVTSIG----QLVLYNARPEDAGLYTCTARNAAG 270
+ N+ + G L + + PED G Y TA N AG
Sbjct: 25530 LSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAG 25570
Score = 39.7 bits (91), Expect = 0.007
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 9/75 (12%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQ-RENLIMRPDQMYGNVVVTSIGQLVLYNARP 255
++ GG+ L + GRP P V W K + R+ I+ V +S LVL N
Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIID--------VTSSFTSLVLDNVNR 16700
Query: 256 EDAGLYTCTARNAAG 270
D+G YT T N++G
Sbjct: 16701 YDSGKYTLTLENSSG 16715
Score = 39.3 bits (90), Expect = 0.009
Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 8/90 (8%)
Query: 183 PVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV- 241
P PP P G A V G P P VTW K++ Q +Y ++
Sbjct: 3764 PCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQ------LCTSVYYTIIH 3817
Query: 242 -VTSIGQLVLYNARPEDAGLYTCTARNAAG 270
G ++ + + ED+GLY C A N G
Sbjct: 3818 NPNGSGTFIVNDPQREDSGLYICKAENMLG 3847
Score = 39.3 bits (90), Expect = 0.009
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 9/75 (12%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI-GQLVLYNARP 255
V GG + VSG+PPP VTW N+ R + T+I +V+ N +
Sbjct: 10231 VHAGGVIRIIAYVSGKPPPTVTW--------NMNERTLPQEATIETTAISSSMVIKNCQR 10282
Query: 256 EDAGLYTCTARNAAG 270
G+Y+ A+N AG
Sbjct: 10283 SHQGVYSLLAKNEAG 10297
Score = 38.9 bits (89), Expect = 0.012
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 7/74 (9%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ GG+A +H GRP P +TW ++ + + + Q+ V T QL + N
Sbjct: 17731 VRAGGSARIHIPFKGRPTPEITWSREEGEFTDKV----QIEKGVNYT---QLSIDNCDRN 17783
Query: 257 DAGLYTCTARNAAG 270
DAG Y N++G
Sbjct: 17784 DAGKYILKLENSSG 17797
Score = 38.5 bits (88), Expect = 0.016
Identities = 47/210 (22%), Positives = 73/210 (34%), Gaps = 21/210 (10%)
Query: 109 DGQPVCRCRDRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLH---LHIVPCKHVLSWPP 165
+G P +R E+E + ++ ++ AE GLH L + L
Sbjct: 3579 EGAPESILHERIEQEIEME-----MKEFSSSFLSAEE--EGLHSAELQLSKINETLELLS 3631
Query: 166 SSPGPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQ 225
SP P G P+ S + +G A+L V G P P + W
Sbjct: 3632 ESPVYPTKFDSEKEGTGPI---FIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNG-- 3686
Query: 226 RENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREP 285
+++ P Y V L++ + ED G YTC A N G L + +
Sbjct: 3687 ---VLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGE 3743
Query: 286 ARDAAPSIPAPAECLPDVQACTGPTSPHLV 315
+ A A+ L + GP PH +
Sbjct: 3744 GHKDTETESAVAKSL---EKLGGPCPPHFL 3770
Score = 38.5 bits (88), Expect = 0.016
Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 7/85 (8%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G + L GRP P W K NL +R D S L + N
Sbjct: 22064 VRAGASIRLFIAYQGRPTPTAVWSKPD---SNLSLRADIH----TTDSFSTLTVENCNRN 22116
Query: 257 DAGLYTCTARNAAGLLRADFPLSVV 281
DAG YT T N +G F + V+
Sbjct: 22117 DAGKYTLTVENNSGSKSITFTVKVL 22141
Score = 38.1 bits (87), Expect = 0.021
Identities = 33/128 (25%), Positives = 52/128 (40%), Gaps = 11/128 (8%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW---EKQSHQ 225
G ET+++ A P Y VG T LH GRP PA+TW +K
Sbjct: 24307 GEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQN 24366
Query: 226 RENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREP 285
EN+ + + Y ++V+ ++ R AG Y N G + A + +Q +P
Sbjct: 24367 SENITIENTEHYTHLVMKNV-------QRKTHAGKYKVQLSNVFGTVDAILDVE-IQDKP 24418
Query: 286 ARDAAPSI 293
+ P +
Sbjct: 24419 DKPTGPIV 24426
Score = 38.1 bits (87), Expect = 0.021
Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 7/103 (6%)
Query: 179 PGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYG 238
P +P L + A++ G S+ SG+P P +TW+K +N + Y
Sbjct: 24717 PAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKGQDLIDN-----NGHYQ 24770
Query: 239 NVVVTSIGQLVLYN-ARPEDAGLYTCTARNAAGLLRADFPLSV 280
+V S LV N +DAG Y A+N G+ + L V
Sbjct: 24771 VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24813
Score = 37.4 bits (85), Expect = 0.036
Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 6/96 (6%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PPA+ + G A C VSG V+W + + ++P + +
Sbjct: 3298 PPAIITPLQDTVTSEGQPARFQCRVSGTDLK-VSWYSKDKK-----IKPSRFFRMTQFED 3351
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
QL + A PED G YT A NA G + + LS+
Sbjct: 3352 TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Score = 37.4 bits (85), Expect = 0.036
Identities = 38/152 (25%), Positives = 56/152 (36%), Gaps = 18/152 (11%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G T L V G+P P V W K + + R ++ + S + L A+
Sbjct: 11908 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATD--LTRSPRVKIDTRADS-SKFSLTKAKRS 11964
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACTGPTSPHLVL 316
D G Y TA N AG A ++V+ + P P L V + + V
Sbjct: 11965 DGGKYVVTATNTAGSFVAYATVNVLDK----------PGPVRNLKIVDVSSDRCT---VC 12011
Query: 317 WHYDPQRGGC--MTFPARGCDGAARGFETYEA 346
W GGC + C+ + TY A
Sbjct: 12012 WDPPEDDGGCEIQNYILEKCETKRMVWSTYSA 12043
Score = 37.0 bits (84), Expect = 0.047
Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 8/100 (8%)
Query: 173 TTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMR 232
T + PG P P + P Q + GG+ C V G P P V W+K + +
Sbjct: 1024 TEEQAGPGE-PAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK-----SGVPLT 1077
Query: 233 PDQMYGNVVVTSIGQ--LVLYNARPEDAGLYTCTARNAAG 270
Y G+ LV+ +DAG YT RN G
Sbjct: 1078 TGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG 1117
Score = 37.0 bits (84), Expect = 0.047
Identities = 23/100 (23%), Positives = 39/100 (39%), Gaps = 5/100 (5%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+ P + + S +VQVG + +SGRP P +TW K + L ++
Sbjct: 16923 IEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTK-----DGLPLKQTTRINVTDSL 16977
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
+ L + +D G Y T N G A + + +
Sbjct: 16978 DLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 17017
Score = 36.6 bits (83), Expect = 0.061
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 6/74 (8%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G L V GRP P VTW K ++R Q+ +V ++ LV+ N+ +
Sbjct: 12313 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDN---VVRKGQV---DLVDTMAFLVIPNSTRD 12366
Query: 257 DAGLYTCTARNAAG 270
D+G Y+ T N AG
Sbjct: 12367 DSGKYSLTLVNPAG 12380
Score = 36.6 bits (83), Expect = 0.061
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 17/105 (16%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQ-LVLYNARP 255
++ G T L+ V GRPPP +TW K N+ +R D++ ++ T L N
Sbjct: 13400 LRAGVTMRLYVPVKGRPPPKITWSK-----PNVNLR-DRIGLDIKSTDFDTFLRCENVNK 13453
Query: 256 EDAGLYTCTARNAAG----------LLRADFPLSVVQREPARDAA 290
DAG Y T N+ G L P++V +E ++D+A
Sbjct: 13454 YDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSA 13498
Score = 36.6 bits (83), Expect = 0.061
Identities = 28/104 (26%), Positives = 39/104 (37%), Gaps = 8/104 (7%)
Query: 170 PPETTARPTPGAAPVPPALYSSPSPQA---VQVGGTASLHCDVSGRPPPAVTWEKQSHQR 226
P ET T V P + S PQ V G L ++GRPPPA +W +
Sbjct: 23415 PRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSK- 23473
Query: 227 ENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+R + T + +L + D G YT +N G
Sbjct: 23474 ----LRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTG 23513
Score = 36.6 bits (83), Expect = 0.061
Identities = 25/88 (28%), Positives = 34/88 (38%), Gaps = 11/88 (12%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW---EKQSHQRENLIMRPDQMYGNVVV 242
P + ++G A L C + GRP P + W K+ Q M D + V
Sbjct: 24228 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24287
Query: 243 TSIGQLVLYNARPEDAGLYTCTARNAAG 270
+ Q ED G+YTC A N G
Sbjct: 24288 MTEEQ--------EDEGVYTCIATNEVG 24307
Score = 36.6 bits (83), Expect = 0.061
Identities = 33/140 (23%), Positives = 50/140 (35%), Gaps = 15/140 (10%)
Query: 173 TTARPTPGAAPVP----PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSH---Q 225
T R T AP P P + + V A +G P P W K Q
Sbjct: 26530 TVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQ 26589
Query: 226 RENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREP 285
+ D+ G L ++ D+GLYTCT +N+AG + + L++ +
Sbjct: 26590 GGKYKLSEDK--GGFF------LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26641
Query: 286 ARDAAPSIPAPAECLPDVQA 305
S +E P +A
Sbjct: 26642 TEAQKVSTQKTSEITPQKKA 26661
Score = 36.2 bits (82), Expect = 0.080
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 5/77 (6%)
Query: 205 LHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCT 264
L + G+P P+V+W+K + D L++Y+ + DAG YT T
Sbjct: 13697 LKIPIKGKPAPSVSWKKGEDP-----LATDTRVSVESSAVNTTLIVYDCQKSDAGKYTIT 13751
Query: 265 ARNAAGLLRADFPLSVV 281
+N AG + VV
Sbjct: 13752 LKNVAGTKEGTISIKVV 13768
Score = 35.4 bits (80), Expect = 0.14
Identities = 24/101 (23%), Positives = 44/101 (43%), Gaps = 7/101 (6%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+ P+L + ++Q G + V GRP P ++W K + NV T
Sbjct: 18005 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTR------VNVEET 18058
Query: 244 SIGQLV-LYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
+ ++ + +D G YT TA N+AG + + V+++
Sbjct: 18059 ATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 18099
Score = 35.0 bits (79), Expect = 0.18
Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 5/102 (4%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN 228
G +TA A PP V+ G L V+G P P V + + + ++
Sbjct: 87 GQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS 146
Query: 229 LIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+ G++ L++ A PED+G Y+ A N+ G
Sbjct: 147 SLDFQISQEGDLY-----SLLIAEAYPEDSGTYSVNATNSVG 183
Score = 35.0 bits (79), Expect = 0.18
Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G L V+G+P P +TW K ++I++ D+ V + + +++
Sbjct: 7397 VKAGTKIELPATVTGKPEPKITWTK-----ADMILKQDKRITIENVPKKSTVTIVDSKRS 7451
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQR 283
D G Y A N G A ++V+ +
Sbjct: 7452 DTGTYIIEAVNVCGRATAVVEVNVLDK 7478
Score = 34.7 bits (78), Expect = 0.23
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPD---QMYGNVVVTSIG--QLVLY 251
V+ G + DV+G P P + W K E +I +P Q+ V S +L +
Sbjct: 9105 VKAGEPVHIPADVTGLPMPKIEWSK----NETVIEKPTDALQITKEEVSRSEAKTELSIP 9160
Query: 252 NARPEDAGLYTCTARNAAGLLRADFPLSVVQR-EPARDAA 290
A ED G YT TA N G + + + V R P R+ A
Sbjct: 9161 KAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9200
Score = 34.7 bits (78), Expect = 0.23
Identities = 32/142 (22%), Positives = 58/142 (40%), Gaps = 18/142 (12%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+PP + P ++ G + V G+P P W+K E+ ++ + + +
Sbjct: 12593 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKK----GEDEVVTSSHLAVHKADS 12647
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDV 303
S L++ + +D+G Y+ TA N++G + V+ AP P P + D+
Sbjct: 12648 S-SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMD-------APGPPQPPFDISDI 12699
Query: 304 QACTGPTSPHLVLWHYDPQRGG 325
A S WH + GG
Sbjct: 12700 DADACSLS-----WHIPLEDGG 12716
Score = 34.7 bits (78), Expect = 0.23
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 7/74 (9%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
++ T L + GRP P V WEK E ++ Q+ V +S LV+ N
Sbjct: 18814 LRASATLRLFVTIKGRPEPEVKWEK----AEGILTDRAQI---EVTSSFTMLVIDNVTRF 18866
Query: 257 DAGLYTCTARNAAG 270
D+G Y T N +G
Sbjct: 18867 DSGRYNLTLENNSG 18880
Score = 34.7 bits (78), Expect = 0.23
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 7/86 (8%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQ--RENLIMRPDQMYGNVVVTSIGQLVLYNAR 254
V+ A+L C V+G P P V W +Q + + L R + G QL++ +
Sbjct: 24634 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKG-----GYHQLIIASVT 24688
Query: 255 PEDAGLYTCTARNAAGLLRADFPLSV 280
+DA +Y A N G + L V
Sbjct: 24689 DDDATVYQVRATNQGGSVSGTASLEV 24714
Score = 33.9 bits (76), Expect = 0.40
Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 200 GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAG 259
G + HC +SG P P + W K + I ++ + + L + PED G
Sbjct: 1259 GMGVTFHCKMSGYPLPKIAWYKDGKR----IKHGERYQMDFLQDGRASLRIPVVLPEDEG 1314
Query: 260 LYTCTARNAAG 270
+YT A N G
Sbjct: 1315 IYTAFASNIKG 1325
Score = 33.9 bits (76), Expect = 0.40
Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+VG T + V GRP P +TW K E ++ ++ + +L + A
Sbjct: 11615 VRVGQTIRILARVKGRPEPDITWTK-----EGKVLVREKRVDLIQDLPRVELQIKEAVRA 11669
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQR 283
D G Y +A+N++G + ++V+ R
Sbjct: 11670 DHGKYIISAKNSSGHAQGSAIVNVLDR 11696
Score = 33.9 bits (76), Expect = 0.40
Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 5/87 (5%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+PPA + V G + GRP PAVTW K +N+ ++
Sbjct: 15841 IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHK-----DNVPLKQTTRVNAESTE 15895
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAG 270
+ L + +A ED G Y N+AG
Sbjct: 15896 NNSLLTIKDACREDVGHYVVKLTNSAG 15922
Score = 33.1 bits (74), Expect = 0.67
Identities = 24/73 (32%), Positives = 30/73 (41%), Gaps = 8/73 (10%)
Query: 200 GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIG--QLVLYNARPED 257
G TA V GRP P W Q N VV+ G L++ A P D
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVN------DYTHKVVIKEDGTQSLIIVPATPSD 1478
Query: 258 AGLYTCTARNAAG 270
+G +T A+N AG
Sbjct: 1479 SGEWTVVAQNRAG 1491
Score = 33.1 bits (74), Expect = 0.67
Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 4/85 (4%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P ++ Q V G A V G+P P W K + I R D++Y ++
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVK----IERSDRIYWYWPEDNV 2087
Query: 246 GQLVLYNARPEDAGLYTCTARNAAG 270
+LV+ + ED+ A N AG
Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAG 2112
Score = 33.1 bits (74), Expect = 0.67
Identities = 18/74 (24%), Positives = 31/74 (41%), Gaps = 5/74 (6%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G ++ D++GRP P ++W K + E N + ++ +
Sbjct: 19496 VKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCI-----RR 19550
Query: 257 DAGLYTCTARNAAG 270
D G Y T +N AG
Sbjct: 19551 DTGQYVLTLKNVAG 19564
Score = 32.7 bits (73), Expect = 0.88
Identities = 21/87 (24%), Positives = 38/87 (43%), Gaps = 5/87 (5%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G + +SG+P P VT R+ + ++ + + + L +
Sbjct: 20183 VRAGSNLKVDIPISGKPLPKVTL-----SRDGVPLKATMRFNTEITAENLTINLKESVTA 20237
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQR 283
DAG Y TA N++G +A + V+ R
Sbjct: 20238 DAGRYEITAANSSGTTKAFINIVVLDR 20264
Score = 32.3 bits (72), Expect = 1.1
Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 5/73 (6%)
Query: 198 QVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPED 257
+ G + V GRP P VTW+K I++ Q + L + D
Sbjct: 14773 KAGDNIKVEIPVLGRPKPTVTWKKGDQ-----ILKQTQRVNFETTATSTILNINECVRSD 14827
Query: 258 AGLYTCTARNAAG 270
+G Y TARN G
Sbjct: 14828 SGPYPLTARNIVG 14840
Score = 32.3 bits (72), Expect = 1.1
Identities = 29/117 (24%), Positives = 46/117 (39%), Gaps = 8/117 (6%)
Query: 170 PPETTARPTPGAAPVPPALYSSPSPQ---AVQVGGTASLHCDVSGRPPPAVTWEKQSHQR 226
P E+T T PP + P + V G + + D+ G+P P + W K +
Sbjct: 16220 PSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 16279
Query: 227 ENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
N ++ TS L + +A D+G Y A+N AG + V+ R
Sbjct: 16280 SNTARL--EIKSTDFATS---LSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDR 16331
Score = 32.3 bits (72), Expect = 1.1
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 4/87 (4%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V G T L D+ G+P P V W K + E R ++ + T+ LV+ +
Sbjct: 18414 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARM-EIKSTIQKTT---LVVKDCIRT 18469
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQR 283
D G Y N G + V+ R
Sbjct: 18470 DGGQYILKLSNVGGTKSIPITVKVLDR 18496
Score = 32.3 bits (72), Expect = 1.1
Identities = 17/86 (19%), Positives = 38/86 (44%), Gaps = 5/86 (5%)
Query: 198 QVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPED 257
+ G + L +SG+P P + W K + ++ + + T + +++ +A +
Sbjct: 20580 RAGTSVKLRAGISGKPAPTIEWYKDDKE-----LQTNALVCVENTTDLASILIKDADRLN 20634
Query: 258 AGLYTCTARNAAGLLRADFPLSVVQR 283
+G Y RNA G A + ++ +
Sbjct: 20635 SGCYELKLRNAMGSASATIRVQILDK 20660
Score = 32.3 bits (72), Expect = 1.1
Identities = 19/60 (31%), Positives = 21/60 (35%), Gaps = 5/60 (8%)
Query: 211 GRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
GRPPP VTW K + D Y S L + D G Y T N G
Sbjct: 20992 GRPPPTVTWRKDEKN-----LGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 21046
Score = 32.0 bits (71), Expect = 1.5
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 9/90 (10%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQS-HQRENLIMRPDQMYGNVVVTSIGQLVLYNARP 255
V++G L G+P P+++W K +E+ +R + + L + NA+
Sbjct: 21270 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKIT------LSIKNAKK 21323
Query: 256 EDAGLYTCTARNAAGLLRADFPLSVVQREP 285
E G YT NA + R P++V+ P
Sbjct: 21324 EHGGKYTVILDNA--VCRIAVPITVITLGP 21351
Score = 32.0 bits (71), Expect = 1.5
Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 7/111 (6%)
Query: 160 VLSWPPSSPGPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW 219
V+S S GP P A + L+ ++ G L V G+P P + W
Sbjct: 22719 VISKGSESTGPVTCRDEYAPPKAELDARLHGDLV--TIRAGSDLVLDAAVGGKPEPKIIW 22776
Query: 220 EKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
K + + L + Y T+ V+ D+G YT T +NA+G
Sbjct: 22777 TKGDKELD-LCEKVSLQYTGKRATA----VIKFCDRSDSGKYTLTVKNASG 22822
Score = 32.0 bits (71), Expect = 1.5
Identities = 35/150 (23%), Positives = 50/150 (33%), Gaps = 17/150 (11%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRP---DQMYGNVV 241
PP + VG ++ P P VTW K + ++P D+ Y
Sbjct: 25384 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQK-----IKPGDNDKKYTFES 25438
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAA-----PSIPAP 296
+ QL + + +D YT ARN G L+V P D+ + A
Sbjct: 25439 DKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLAN 25498
Query: 297 AECLPDVQAC----TGPTSPHLVLWHYDPQ 322
AEC C P + W D Q
Sbjct: 25499 AECQEGQSVCFEIRVSGIPPPTLKWEKDGQ 25528
Score = 31.6 bits (70), Expect = 2.0
Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Query: 185 PPALYSSPSPQ-AVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
PP L+ + ++VG +L SG+P P V+W K E ++ D+ +
Sbjct: 10512 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKD----EADVLEDDRTHIKTTPA 10567
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
++ L A+ D+G Y N+ G + ++VV R
Sbjct: 10568 TLA-LEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR 10606
Score = 31.6 bits (70), Expect = 2.0
Identities = 26/103 (25%), Positives = 40/103 (38%), Gaps = 13/103 (12%)
Query: 197 VQVGGTASLHC-DVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARP 255
++ G T L+ + G+P P +W K +RP + + L + A
Sbjct: 14085 IKAGDTIVLNAISILGKPLPKSSWSKAGKD-----IRPSDITQITSTPTSSMLTIKYATR 14139
Query: 256 EDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAE 298
+DAG YT TA N G ++V+ P P P E
Sbjct: 14140 KDAGEYTITATNPFGTKVEHVKVTVLD-------VPGPPGPVE 14175
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/86 (23%), Positives = 35/86 (40%), Gaps = 5/86 (5%)
Query: 198 QVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPED 257
+ G ++ +SGRP P VTW + E + ++ L + ++ D
Sbjct: 22355 KAGSPFTIDVPISGRPAPKVTW-----KLEEMRLKETDRVSITTTKDRTTLTVKDSMRGD 22409
Query: 258 AGLYTCTARNAAGLLRADFPLSVVQR 283
+G Y T N AG+ + V+ R
Sbjct: 22410 SGRYFLTLENTAGVKTFSVTVVVIGR 22435
Score = 30.8 bits (68), Expect = 3.3
Identities = 29/116 (25%), Positives = 41/116 (35%), Gaps = 18/116 (15%)
Query: 211 GRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
GRP V W K + + + VTS+ + A ED G Y N+AG
Sbjct: 19115 GRPQATVNWRKDGQTLKETTRV--NVSSSKTVTSLS---IKEASKEDVGTYELCVSNSAG 19169
Query: 271 LLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACTGPTSPHLVLWHYDPQRGGC 326
+ + V+ R P P P D +C T + W+ GGC
Sbjct: 19170 SITVPITIIVLDR-------PGPPGPIRI--DEVSCDSIT----ISWNPPEYDGGC 19212
Score = 30.4 bits (67), Expect = 4.4
Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 9/75 (12%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT-SIGQLVLYNARP 255
V+ G + + + GRP P VTW K + +N N+ T S L++
Sbjct: 14483 VRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN--------RANIENTESFTLLIIPECNR 14534
Query: 256 EDAGLYTCTARNAAG 270
D G + T N AG
Sbjct: 14535 YDTGKFVMTIENPAG 14549
Score = 30.0 bits (66), Expect = 5.7
Identities = 24/95 (25%), Positives = 34/95 (35%), Gaps = 5/95 (5%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P ++ V+ G TA C + VTW + + E GN+
Sbjct: 3489 PKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQF--- 3545
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
L + N + D GLY+C N G LSV
Sbjct: 3546 --LTICNVQLVDQGLYSCIVHNDCGERTTSAVLSV 3578
Score = 29.3 bits (64), Expect = 9.7
Identities = 22/98 (22%), Positives = 36/98 (36%), Gaps = 11/98 (11%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEK---QSHQRENLIMRPDQMYGNVVV 242
P + P V +G A C++ P W K + ++ + +R +
Sbjct: 4529 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKY------ 4582
Query: 243 TSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
I L + + D G YTC A N G + L+V
Sbjct: 4583 --ISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4618
Score = 29.3 bits (64), Expect = 9.7
Identities = 23/91 (25%), Positives = 36/91 (39%), Gaps = 12/91 (13%)
Query: 213 PPPAVTWEKQSHQ---RENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAA 269
P P V+W K + + L M+ D + ++ V + DAG+YT T N
Sbjct: 8109 PVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA--------DAGIYTITLENKL 8160
Query: 270 GLLRADFPLSVVQRE-PARDAAPSIPAPAEC 299
G A + V+ P +D S + C
Sbjct: 8161 GSATASINVKVIGLPGPCKDIKASDITKSSC 8191
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 59.7 bits (143), Expect = 7e-09
Identities = 38/110 (34%), Positives = 55/110 (50%), Gaps = 6/110 (5%)
Query: 172 ETTARPTPGAAPV-PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLI 230
ET P P PV PP L S V G + +L C +SG P P VTW ++ +Q E+ I
Sbjct: 882 ETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSI 941
Query: 231 MRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
+ + I +L++ A ED+G +TC+A N AG + L+V
Sbjct: 942 -----DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 52.4 bits (124), Expect = 1e-06
Identities = 37/124 (29%), Positives = 51/124 (41%), Gaps = 21/124 (16%)
Query: 182 APVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN----LIMRPDQMY 237
AP PP + P VQ G A +SGRP P ++W K+ + Q Y
Sbjct: 3189 APEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3248
Query: 238 GNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPA 297
L+L A PEDA +YTC A+N G+ LSV P + +P
Sbjct: 3249 ---------TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV--------EVPEVVSPD 3291
Query: 298 ECLP 301
+ +P
Sbjct: 3292 QEMP 3295
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 13/123 (10%)
Query: 164 PPSSPGPPETTARPTPGAAPVPPALYSSPSPQA---VQVGGTASLHCDVSGRPPPAVTWE 220
PPS P P T A VPP + S + ++ V+ G L V G+P P V+W+
Sbjct: 12904 PPSEPSDPVTIL-----AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWK 12958
Query: 221 KQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
K + +++P + + ++ L L++ +D+G YT TA N++G A L V
Sbjct: 12959 K-----DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 13013
Query: 281 VQR 283
+ +
Sbjct: 13014 LDK 13016
Score = 47.4 bits (111), Expect = 3e-05
Identities = 32/108 (29%), Positives = 48/108 (44%), Gaps = 13/108 (12%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT-- 243
PA S P Q + G C++SG P P + W K + P + NV ++
Sbjct: 26762 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNN--------LPISISSNVSISRS 26813
Query: 244 -SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQ--REPARD 288
++ L + NA D+G YT A+N G A L V+ EP+R+
Sbjct: 26814 RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSRE 26861
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P+ S V G T H VSG P P + W H ++ ++ D ++ T +
Sbjct: 3419 PSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQW---FHNQQLILPTKDVVFHFEESTGM 3475
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREP 285
+++ +A E AG Y+C A N+AG L+V + P
Sbjct: 3476 ALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAP 3515
Score = 45.1 bits (105), Expect = 2e-04
Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 10/96 (10%)
Query: 195 QAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIG-QLVLYNA 253
Q ++VG T L + G P P VTW+K+ R + VT +G +L + NA
Sbjct: 10856 QHIKVGDTLRLSAIIKGVPFPKVTWKKED--------RDAPTKARIDVTPVGSKLEIRNA 10907
Query: 254 RPEDAGLYTCTARNAAGLLRADFPLSVVQRE-PARD 288
ED G+Y+ T N AG + V+ + P RD
Sbjct: 10908 AHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRD 10943
Score = 43.5 bits (101), Expect = 5e-04
Identities = 32/111 (28%), Positives = 43/111 (38%), Gaps = 6/111 (5%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P + P P V G TA C V+G P P V W + LI + + V I
Sbjct: 1795 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNW----YLNGQLIRKSKRF--RVRYDGI 1848
Query: 246 GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAP 296
L + + + D G TA N G++ L + QRE R P P
Sbjct: 1849 HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEP 1899
Score = 43.5 bits (101), Expect = 5e-04
Identities = 37/129 (28%), Positives = 50/129 (38%), Gaps = 18/129 (13%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
++ G L DVSGRPPP + W K + E + + LV ++
Sbjct: 15101 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIK-----IADFSTNLVNKDSTRR 15155
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACTGPTSPHLVL 316
D+G YT TA N G + F + V+ R P P E A T TS VL
Sbjct: 15156 DSGAYTLTATNPGGFAKHIFNVKVLDR----------PGPPE---GPLAVTEVTSEKCVL 15202
Query: 317 WHYDPQRGG 325
+ P G
Sbjct: 15203 SWFPPLDDG 15211
Score = 42.7 bits (99), Expect = 9e-04
Identities = 37/139 (26%), Positives = 56/139 (40%), Gaps = 16/139 (11%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQA---VQVGGTASLHCDVSGRPPPAVTWEKQSHQ 225
GPP T T PPA+ S + + G T + V+GRP P W K+ +
Sbjct: 8713 GPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGE 8772
Query: 226 RENLIMRPDQMYGNVVVTSIG---QLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQ 282
+ VV+ ++G +L++ +A +D G Y TA N+ G A + V
Sbjct: 8773 LDK---------DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFD 8823
Query: 283 -REPARDAAPSIPAPAECL 300
P D P + CL
Sbjct: 8824 VPGPVLDLKPVVTNRKMCL 8842
Score = 42.7 bits (99), Expect = 9e-04
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 9/75 (12%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQS-HQRENLIMRPDQMYGNVVVTSIGQLVLYNARP 255
++ G + L VSGRPPP +TW KQ I+ + Y ++V + +
Sbjct: 23086 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY------- 23138
Query: 256 EDAGLYTCTARNAAG 270
DAG YT A N +G
Sbjct: 23139 -DAGKYTIEAENQSG 23152
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/128 (22%), Positives = 47/128 (36%), Gaps = 5/128 (3%)
Query: 188 LYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQ 247
+ + P V G +A CD G P P VTW R+ ++ +
Sbjct: 26191 ILTKPRSMTVYEGESARFSCDTDGEPVPTVTW-----LRKGQVLSTSARHQVTTTKYKST 26245
Query: 248 LVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACT 307
+ + + D G Y+ N+ G A+F L++ + A S P P V++
Sbjct: 26246 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPE 26305
Query: 308 GPTSPHLV 315
SP V
Sbjct: 26306 AVKSPKRV 26313
Score = 41.6 bits (96), Expect = 0.002
Identities = 32/117 (27%), Positives = 47/117 (40%), Gaps = 6/117 (5%)
Query: 171 PETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW----EKQSHQR 226
P T P P P V+ G ++ + G P P +TW K+ +
Sbjct: 9730 PSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNK 9789
Query: 227 ENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
E ++ D +VV LV+ +R D GLYT TA N G + L+V+ R
Sbjct: 9790 EPVLY--DTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGR 9844
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 7/84 (8%)
Query: 185 PPALYSSP-SPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
PP ++ P Q V+ G TA L C+VS R V W K + + + Y V
Sbjct: 5911 PPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTE-----ILKSKKYEIVADG 5964
Query: 244 SIGQLVLYNARPEDAGLYTCTARN 267
+ +LV+++ PED YTC A++
Sbjct: 5965 RVRKLVIHDCTPEDIKTYTCDAKD 5988
Score = 41.2 bits (95), Expect = 0.002
Identities = 38/149 (25%), Positives = 59/149 (39%), Gaps = 27/149 (18%)
Query: 184 VPPALYSSPS---PQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNV 240
VPP + P ++ G + + V GRP P VTW K + E + N+
Sbjct: 21582 VPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM--------NM 21633
Query: 241 VVTSI---GQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPA 297
+T + L + +A + G+YT A+NA+G +A+ + VQ P + P
Sbjct: 21634 EITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVK-VQDTPGKVVGPI----- 21687
Query: 298 ECLPDVQACTGPTSPHLVLWHYDPQRGGC 326
T T + LW P GC
Sbjct: 21688 -------RFTNITGEKMTLWWDAPLNDGC 21709
Score = 40.4 bits (93), Expect = 0.004
Identities = 23/94 (24%), Positives = 42/94 (44%), Gaps = 9/94 (9%)
Query: 180 GAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWE---KQSHQRENLIMRPDQM 236
G +PP + + PS ++ G ++ C +G P P VTW ++ H +E +
Sbjct: 26951 GIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIEN- 27009
Query: 237 YGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+ L++ + + +D GLYT + N G
Sbjct: 27010 -----TDDLTTLIIMDVQKQDGGLYTLSLGNEFG 27038
Score = 40.0 bits (92), Expect = 0.006
Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 12/101 (11%)
Query: 174 TARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRP 233
T P P + + P + Q G + VSG PPP + WEK +P
Sbjct: 25411 TLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG--------QP 25462
Query: 234 DQMYGNVVVTSIG----QLVLYNARPEDAGLYTCTARNAAG 270
+ N+ + G L + + PED G Y TA N AG
Sbjct: 25463 LSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAG 25503
Score = 39.7 bits (91), Expect = 0.007
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 9/75 (12%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQ-RENLIMRPDQMYGNVVVTSIGQLVLYNARP 255
++ GG+ L + GRP P V W K + R+ I+ V +S LVL N
Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIID--------VTSSFTSLVLDNVNR 16633
Query: 256 EDAGLYTCTARNAAG 270
D+G YT T N++G
Sbjct: 16634 YDSGKYTLTLENSSG 16648
Score = 39.3 bits (90), Expect = 0.009
Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 8/90 (8%)
Query: 183 PVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVV- 241
P PP P G A V G P P VTW K++ Q +Y ++
Sbjct: 3697 PCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQ------LCTSVYYTIIH 3750
Query: 242 -VTSIGQLVLYNARPEDAGLYTCTARNAAG 270
G ++ + + ED+GLY C A N G
Sbjct: 3751 NPNGSGTFIVNDPQREDSGLYICKAENMLG 3780
Score = 39.3 bits (90), Expect = 0.009
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 9/75 (12%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI-GQLVLYNARP 255
V GG + VSG+PPP VTW N+ R + T+I +V+ N +
Sbjct: 10164 VHAGGVIRIIAYVSGKPPPTVTW--------NMNERTLPQEATIETTAISSSMVIKNCQR 10215
Query: 256 EDAGLYTCTARNAAG 270
G+Y+ A+N AG
Sbjct: 10216 SHQGVYSLLAKNEAG 10230
Score = 38.9 bits (89), Expect = 0.012
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 7/74 (9%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ GG+A +H GRP P +TW ++ + + + Q+ V T QL + N
Sbjct: 17664 VRAGGSARIHIPFKGRPTPEITWSREEGEFTDKV----QIEKGVNYT---QLSIDNCDRN 17716
Query: 257 DAGLYTCTARNAAG 270
DAG Y N++G
Sbjct: 17717 DAGKYILKLENSSG 17730
Score = 38.5 bits (88), Expect = 0.016
Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 7/85 (8%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G + L GRP P W K NL +R D S L + N
Sbjct: 21997 VRAGASIRLFIAYQGRPTPTAVWSKPD---SNLSLRADIH----TTDSFSTLTVENCNRN 22049
Query: 257 DAGLYTCTARNAAGLLRADFPLSVV 281
DAG YT T N +G F + V+
Sbjct: 22050 DAGKYTLTVENNSGSKSITFTVKVL 22074
Score = 38.1 bits (87), Expect = 0.021
Identities = 33/128 (25%), Positives = 52/128 (40%), Gaps = 11/128 (8%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW---EKQSHQ 225
G ET+++ A P Y VG T LH GRP PA+TW +K
Sbjct: 24240 GEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQN 24299
Query: 226 RENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREP 285
EN+ + + Y ++V+ ++ R AG Y N G + A + +Q +P
Sbjct: 24300 SENITIENTEHYTHLVMKNV-------QRKTHAGKYKVQLSNVFGTVDAILDVE-IQDKP 24351
Query: 286 ARDAAPSI 293
+ P +
Sbjct: 24352 DKPTGPIV 24359
Score = 38.1 bits (87), Expect = 0.021
Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 7/103 (6%)
Query: 179 PGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYG 238
P +P L + A++ G S+ SG+P P +TW+K +N + Y
Sbjct: 24650 PAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKGQDLIDN-----NGHYQ 24703
Query: 239 NVVVTSIGQLVLYN-ARPEDAGLYTCTARNAAGLLRADFPLSV 280
+V S LV N +DAG Y A+N G+ + L V
Sbjct: 24704 VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24746
Score = 37.4 bits (85), Expect = 0.036
Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 6/96 (6%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTS 244
PPA+ + G A C VSG V+W + + ++P + +
Sbjct: 3298 PPAIITPLQDTVTSEGQPARFQCRVSGTDLK-VSWYSKDKK-----IKPSRFFRMTQFED 3351
Query: 245 IGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
QL + A PED G YT A NA G + + LS+
Sbjct: 3352 TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Score = 37.4 bits (85), Expect = 0.036
Identities = 42/183 (22%), Positives = 64/183 (34%), Gaps = 16/183 (8%)
Query: 136 YNRCYMDAEACLRGLH---LHIVPCKHVLSWPPSSPGPPETTARPTPGAAPVPPALYSSP 192
++ ++ AE GLH L + L SP P G P+
Sbjct: 3534 FSSSFLSAEE--EGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPI---FIKEV 3588
Query: 193 SPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYN 252
S + +G A+L V G P P + W +++ P Y V L++
Sbjct: 3589 SNADISMGDVATLSVTVIGIPKPKIQWFFNG-----VLLTPSADYKFVFDGDDHSLIILF 3643
Query: 253 ARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACTGPTSP 312
+ ED G YTC A N G L + + + A A+ L + GP P
Sbjct: 3644 TKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSL---EKLGGPCPP 3700
Query: 313 HLV 315
H +
Sbjct: 3701 HFL 3703
Score = 37.4 bits (85), Expect = 0.036
Identities = 38/152 (25%), Positives = 56/152 (36%), Gaps = 18/152 (11%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G T L V G+P P V W K + + R ++ + S + L A+
Sbjct: 11841 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATD--LTRSPRVKIDTRADS-SKFSLTKAKRS 11897
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACTGPTSPHLVL 316
D G Y TA N AG A ++V+ + P P L V + + V
Sbjct: 11898 DGGKYVVTATNTAGSFVAYATVNVLDK----------PGPVRNLKIVDVSSDRCT---VC 11944
Query: 317 WHYDPQRGGC--MTFPARGCDGAARGFETYEA 346
W GGC + C+ + TY A
Sbjct: 11945 WDPPEDDGGCEIQNYILEKCETKRMVWSTYSA 11976
Score = 37.0 bits (84), Expect = 0.047
Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 8/100 (8%)
Query: 173 TTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMR 232
T + PG P P + P Q + GG+ C V G P P V W+K + +
Sbjct: 1024 TEEQAGPGE-PAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK-----SGVPLT 1077
Query: 233 PDQMYGNVVVTSIGQ--LVLYNARPEDAGLYTCTARNAAG 270
Y G+ LV+ +DAG YT RN G
Sbjct: 1078 TGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG 1117
Score = 37.0 bits (84), Expect = 0.047
Identities = 23/100 (23%), Positives = 39/100 (39%), Gaps = 5/100 (5%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+ P + + S +VQVG + +SGRP P +TW K + L ++
Sbjct: 16856 IEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTK-----DGLPLKQTTRINVTDSL 16910
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
+ L + +D G Y T N G A + + +
Sbjct: 16911 DLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 16950
Score = 36.6 bits (83), Expect = 0.061
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 6/74 (8%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G L V GRP P VTW K ++R Q+ +V ++ LV+ N+ +
Sbjct: 12246 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDN---VVRKGQV---DLVDTMAFLVIPNSTRD 12299
Query: 257 DAGLYTCTARNAAG 270
D+G Y+ T N AG
Sbjct: 12300 DSGKYSLTLVNPAG 12313
Score = 36.6 bits (83), Expect = 0.061
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 17/105 (16%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQ-LVLYNARP 255
++ G T L+ V GRPPP +TW K N+ +R D++ ++ T L N
Sbjct: 13333 LRAGVTMRLYVPVKGRPPPKITWSK-----PNVNLR-DRIGLDIKSTDFDTFLRCENVNK 13386
Query: 256 EDAGLYTCTARNAAG----------LLRADFPLSVVQREPARDAA 290
DAG Y T N+ G L P++V +E ++D+A
Sbjct: 13387 YDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSA 13431
Score = 36.6 bits (83), Expect = 0.061
Identities = 28/104 (26%), Positives = 39/104 (37%), Gaps = 8/104 (7%)
Query: 170 PPETTARPTPGAAPVPPALYSSPSPQA---VQVGGTASLHCDVSGRPPPAVTWEKQSHQR 226
P ET T V P + S PQ V G L ++GRPPPA +W +
Sbjct: 23348 PRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSK- 23406
Query: 227 ENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+R + T + +L + D G YT +N G
Sbjct: 23407 ----LRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTG 23446
Score = 36.6 bits (83), Expect = 0.061
Identities = 25/88 (28%), Positives = 34/88 (38%), Gaps = 11/88 (12%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW---EKQSHQRENLIMRPDQMYGNVVV 242
P + ++G A L C + GRP P + W K+ Q M D + V
Sbjct: 24161 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24220
Query: 243 TSIGQLVLYNARPEDAGLYTCTARNAAG 270
+ Q ED G+YTC A N G
Sbjct: 24221 MTEEQ--------EDEGVYTCIATNEVG 24240
Score = 36.6 bits (83), Expect = 0.061
Identities = 33/140 (23%), Positives = 50/140 (35%), Gaps = 15/140 (10%)
Query: 173 TTARPTPGAAPVP----PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSH---Q 225
T R T AP P P + + V A +G P P W K Q
Sbjct: 26463 TVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQ 26522
Query: 226 RENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREP 285
+ D+ G L ++ D+GLYTCT +N+AG + + L++ +
Sbjct: 26523 GGKYKLSEDK--GGFF------LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26574
Query: 286 ARDAAPSIPAPAECLPDVQA 305
S +E P +A
Sbjct: 26575 TEAQKVSTQKTSEITPQKKA 26594
Score = 36.2 bits (82), Expect = 0.080
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 5/77 (6%)
Query: 205 LHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCT 264
L + G+P P+V+W+K + D L++Y+ + DAG YT T
Sbjct: 13630 LKIPIKGKPAPSVSWKKGEDP-----LATDTRVSVESSAVNTTLIVYDCQKSDAGKYTIT 13684
Query: 265 ARNAAGLLRADFPLSVV 281
+N AG + VV
Sbjct: 13685 LKNVAGTKEGTISIKVV 13701
Score = 35.4 bits (80), Expect = 0.14
Identities = 24/101 (23%), Positives = 44/101 (43%), Gaps = 7/101 (6%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+ P+L + ++Q G + V GRP P ++W K + NV T
Sbjct: 17938 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTR------VNVEET 17991
Query: 244 SIGQLV-LYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
+ ++ + +D G YT TA N+AG + + V+++
Sbjct: 17992 ATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 18032
Score = 35.0 bits (79), Expect = 0.18
Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 5/102 (4%)
Query: 169 GPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQREN 228
G +TA A PP V+ G L V+G P P V + + + ++
Sbjct: 87 GQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS 146
Query: 229 LIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
+ G++ L++ A PED+G Y+ A N+ G
Sbjct: 147 SLDFQISQEGDLY-----SLLIAEAYPEDSGTYSVNATNSVG 183
Score = 35.0 bits (79), Expect = 0.18
Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G L V+G+P P +TW K ++I++ D+ V + + +++
Sbjct: 7330 VKAGTKIELPATVTGKPEPKITWTK-----ADMILKQDKRITIENVPKKSTVTIVDSKRS 7384
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQR 283
D G Y A N G A ++V+ +
Sbjct: 7385 DTGTYIIEAVNVCGRATAVVEVNVLDK 7411
Score = 34.7 bits (78), Expect = 0.23
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPD---QMYGNVVVTSIG--QLVLY 251
V+ G + DV+G P P + W K E +I +P Q+ V S +L +
Sbjct: 9038 VKAGEPVHIPADVTGLPMPKIEWSK----NETVIEKPTDALQITKEEVSRSEAKTELSIP 9093
Query: 252 NARPEDAGLYTCTARNAAGLLRADFPLSVVQR-EPARDAA 290
A ED G YT TA N G + + + V R P R+ A
Sbjct: 9094 KAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9133
Score = 34.7 bits (78), Expect = 0.23
Identities = 32/142 (22%), Positives = 58/142 (40%), Gaps = 18/142 (12%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+PP + P ++ G + V G+P P W+K E+ ++ + + +
Sbjct: 12526 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKK----GEDEVVTSSHLAVHKADS 12580
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDV 303
S L++ + +D+G Y+ TA N++G + V+ AP P P + D+
Sbjct: 12581 S-SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMD-------APGPPQPPFDISDI 12632
Query: 304 QACTGPTSPHLVLWHYDPQRGG 325
A S WH + GG
Sbjct: 12633 DADACSLS-----WHIPLEDGG 12649
Score = 34.7 bits (78), Expect = 0.23
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 7/74 (9%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
++ T L + GRP P V WEK E ++ Q+ V +S LV+ N
Sbjct: 18747 LRASATLRLFVTIKGRPEPEVKWEK----AEGILTDRAQI---EVTSSFTMLVIDNVTRF 18799
Query: 257 DAGLYTCTARNAAG 270
D+G Y T N +G
Sbjct: 18800 DSGRYNLTLENNSG 18813
Score = 34.7 bits (78), Expect = 0.23
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 7/86 (8%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQ--RENLIMRPDQMYGNVVVTSIGQLVLYNAR 254
V+ A+L C V+G P P V W +Q + + L R + G QL++ +
Sbjct: 24567 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKG-----GYHQLIIASVT 24621
Query: 255 PEDAGLYTCTARNAAGLLRADFPLSV 280
+DA +Y A N G + L V
Sbjct: 24622 DDDATVYQVRATNQGGSVSGTASLEV 24647
Score = 33.9 bits (76), Expect = 0.40
Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 200 GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAG 259
G + HC +SG P P + W K + I ++ + + L + PED G
Sbjct: 1259 GMGVTFHCKMSGYPLPKIAWYKDGKR----IKHGERYQMDFLQDGRASLRIPVVLPEDEG 1314
Query: 260 LYTCTARNAAG 270
+YT A N G
Sbjct: 1315 IYTAFASNIKG 1325
Score = 33.9 bits (76), Expect = 0.40
Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+VG T + V GRP P +TW K E ++ ++ + +L + A
Sbjct: 11548 VRVGQTIRILARVKGRPEPDITWTK-----EGKVLVREKRVDLIQDLPRVELQIKEAVRA 11602
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQR 283
D G Y +A+N++G + ++V+ R
Sbjct: 11603 DHGKYIISAKNSSGHAQGSAIVNVLDR 11629
Score = 33.9 bits (76), Expect = 0.40
Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 5/87 (5%)
Query: 184 VPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
+PPA + V G + GRP PAVTW K +N+ ++
Sbjct: 15774 IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHK-----DNVPLKQTTRVNAESTE 15828
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAG 270
+ L + +A ED G Y N+AG
Sbjct: 15829 NNSLLTIKDACREDVGHYVVKLTNSAG 15855
Score = 33.1 bits (74), Expect = 0.67
Identities = 24/73 (32%), Positives = 30/73 (41%), Gaps = 8/73 (10%)
Query: 200 GGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIG--QLVLYNARPED 257
G TA V GRP P W Q N VV+ G L++ A P D
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVN------DYTHKVVIKEDGTQSLIIVPATPSD 1478
Query: 258 AGLYTCTARNAAG 270
+G +T A+N AG
Sbjct: 1479 SGEWTVVAQNRAG 1491
Score = 33.1 bits (74), Expect = 0.67
Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 4/85 (4%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSI 245
P ++ Q V G A V G+P P W K + I R D++Y ++
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVK----IERSDRIYWYWPEDNV 2087
Query: 246 GQLVLYNARPEDAGLYTCTARNAAG 270
+LV+ + ED+ A N AG
Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAG 2112
Score = 33.1 bits (74), Expect = 0.67
Identities = 18/74 (24%), Positives = 31/74 (41%), Gaps = 5/74 (6%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G ++ D++GRP P ++W K + E N + ++ +
Sbjct: 19429 VKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCI-----RR 19483
Query: 257 DAGLYTCTARNAAG 270
D G Y T +N AG
Sbjct: 19484 DTGQYVLTLKNVAG 19497
Score = 32.7 bits (73), Expect = 0.88
Identities = 21/87 (24%), Positives = 38/87 (43%), Gaps = 5/87 (5%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V+ G + +SG+P P VT R+ + ++ + + + L +
Sbjct: 20116 VRAGSNLKVDIPISGKPLPKVTL-----SRDGVPLKATMRFNTEITAENLTINLKESVTA 20170
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQR 283
DAG Y TA N++G +A + V+ R
Sbjct: 20171 DAGRYEITAANSSGTTKAFINIVVLDR 20197
Score = 32.3 bits (72), Expect = 1.1
Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 5/73 (6%)
Query: 198 QVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPED 257
+ G + V GRP P VTW+K I++ Q + L + D
Sbjct: 14706 KAGDNIKVEIPVLGRPKPTVTWKKGDQ-----ILKQTQRVNFETTATSTILNINECVRSD 14760
Query: 258 AGLYTCTARNAAG 270
+G Y TARN G
Sbjct: 14761 SGPYPLTARNIVG 14773
Score = 32.3 bits (72), Expect = 1.1
Identities = 29/117 (24%), Positives = 46/117 (39%), Gaps = 8/117 (6%)
Query: 170 PPETTARPTPGAAPVPPALYSSPSPQ---AVQVGGTASLHCDVSGRPPPAVTWEKQSHQR 226
P E+T T PP + P + V G + + D+ G+P P + W K +
Sbjct: 16153 PSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 16212
Query: 227 ENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
N ++ TS L + +A D+G Y A+N AG + V+ R
Sbjct: 16213 SNTARL--EIKSTDFATS---LSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDR 16264
Score = 32.3 bits (72), Expect = 1.1
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 4/87 (4%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPE 256
V G T L D+ G+P P V W K + E R ++ + T+ LV+ +
Sbjct: 18347 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARM-EIKSTIQKTT---LVVKDCIRT 18402
Query: 257 DAGLYTCTARNAAGLLRADFPLSVVQR 283
D G Y N G + V+ R
Sbjct: 18403 DGGQYILKLSNVGGTKSIPITVKVLDR 18429
Score = 32.3 bits (72), Expect = 1.1
Identities = 17/86 (19%), Positives = 38/86 (44%), Gaps = 5/86 (5%)
Query: 198 QVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPED 257
+ G + L +SG+P P + W K + ++ + + T + +++ +A +
Sbjct: 20513 RAGTSVKLRAGISGKPAPTIEWYKDDKE-----LQTNALVCVENTTDLASILIKDADRLN 20567
Query: 258 AGLYTCTARNAAGLLRADFPLSVVQR 283
+G Y RNA G A + ++ +
Sbjct: 20568 SGCYELKLRNAMGSASATIRVQILDK 20593
Score = 32.3 bits (72), Expect = 1.1
Identities = 19/60 (31%), Positives = 21/60 (35%), Gaps = 5/60 (8%)
Query: 211 GRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
GRPPP VTW K + D Y S L + D G Y T N G
Sbjct: 20925 GRPPPTVTWRKDEKN-----LGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 20979
Score = 32.0 bits (71), Expect = 1.5
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 9/90 (10%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQS-HQRENLIMRPDQMYGNVVVTSIGQLVLYNARP 255
V++G L G+P P+++W K +E+ +R + + L + NA+
Sbjct: 21203 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKIT------LSIKNAKK 21256
Query: 256 EDAGLYTCTARNAAGLLRADFPLSVVQREP 285
E G YT NA + R P++V+ P
Sbjct: 21257 EHGGKYTVILDNA--VCRIAVPITVITLGP 21284
Score = 32.0 bits (71), Expect = 1.5
Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 7/111 (6%)
Query: 160 VLSWPPSSPGPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTW 219
V+S S GP P A + L+ ++ G L V G+P P + W
Sbjct: 22652 VISKGSESTGPVTCRDEYAPPKAELDARLHGDLV--TIRAGSDLVLDAAVGGKPEPKIIW 22709
Query: 220 EKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
K + + L + Y T+ V+ D+G YT T +NA+G
Sbjct: 22710 TKGDKELD-LCEKVSLQYTGKRATA----VIKFCDRSDSGKYTLTVKNASG 22755
Score = 32.0 bits (71), Expect = 1.5
Identities = 35/150 (23%), Positives = 50/150 (33%), Gaps = 17/150 (11%)
Query: 185 PPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRP---DQMYGNVV 241
PP + VG ++ P P VTW K + ++P D+ Y
Sbjct: 25317 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQK-----IKPGDNDKKYTFES 25371
Query: 242 VTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAA-----PSIPAP 296
+ QL + + +D YT ARN G L+V P D+ + A
Sbjct: 25372 DKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLAN 25431
Query: 297 AECLPDVQAC----TGPTSPHLVLWHYDPQ 322
AEC C P + W D Q
Sbjct: 25432 AECQEGQSVCFEIRVSGIPPPTLKWEKDGQ 25461
Score = 31.6 bits (70), Expect = 2.0
Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Query: 185 PPALYSSPSPQ-AVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT 243
PP L+ + ++VG +L SG+P P V+W K E ++ D+ +
Sbjct: 10445 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKD----EADVLEDDRTHIKTTPA 10500
Query: 244 SIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQR 283
++ L A+ D+G Y N+ G + ++VV R
Sbjct: 10501 TLA-LEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR 10539
Score = 31.6 bits (70), Expect = 2.0
Identities = 26/103 (25%), Positives = 40/103 (38%), Gaps = 13/103 (12%)
Query: 197 VQVGGTASLHC-DVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARP 255
++ G T L+ + G+P P +W K +RP + + L + A
Sbjct: 14018 IKAGDTIVLNAISILGKPLPKSSWSKAGKD-----IRPSDITQITSTPTSSMLTIKYATR 14072
Query: 256 EDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAE 298
+DAG YT TA N G ++V+ P P P E
Sbjct: 14073 KDAGEYTITATNPFGTKVEHVKVTVLD-------VPGPPGPVE 14108
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/86 (23%), Positives = 35/86 (40%), Gaps = 5/86 (5%)
Query: 198 QVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPED 257
+ G ++ +SGRP P VTW + E + ++ L + ++ D
Sbjct: 22288 KAGSPFTIDVPISGRPAPKVTW-----KLEEMRLKETDRVSITTTKDRTTLTVKDSMRGD 22342
Query: 258 AGLYTCTARNAAGLLRADFPLSVVQR 283
+G Y T N AG+ + V+ R
Sbjct: 22343 SGRYFLTLENTAGVKTFSVTVVVIGR 22368
Score = 30.8 bits (68), Expect = 3.3
Identities = 29/116 (25%), Positives = 41/116 (35%), Gaps = 18/116 (15%)
Query: 211 GRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAG 270
GRP V W K + + + VTS+ + A ED G Y N+AG
Sbjct: 19048 GRPQATVNWRKDGQTLKETTRV--NVSSSKTVTSLS---IKEASKEDVGTYELCVSNSAG 19102
Query: 271 LLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACTGPTSPHLVLWHYDPQRGGC 326
+ + V+ R P P P D +C T + W+ GGC
Sbjct: 19103 SITVPITIIVLDR-------PGPPGPIRI--DEVSCDSIT----ISWNPPEYDGGC 19145
Score = 30.4 bits (67), Expect = 4.4
Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 9/75 (12%)
Query: 197 VQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVT-SIGQLVLYNARP 255
V+ G + + + GRP P VTW K + +N N+ T S L++
Sbjct: 14416 VRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN--------RANIENTESFTLLIIPECNR 14467
Query: 256 EDAGLYTCTARNAAG 270
D G + T N AG
Sbjct: 14468 YDTGKFVMTIENPAG 14482
Score = 29.3 bits (64), Expect = 9.7
Identities = 22/98 (22%), Positives = 36/98 (36%), Gaps = 11/98 (11%)
Query: 186 PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEK---QSHQRENLIMRPDQMYGNVVV 242
P + P V +G A C++ P W K + ++ + +R +
Sbjct: 4462 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKY------ 4515
Query: 243 TSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSV 280
I L + + D G YTC A N G + L+V
Sbjct: 4516 --ISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4551
Score = 29.3 bits (64), Expect = 9.7
Identities = 23/91 (25%), Positives = 36/91 (39%), Gaps = 12/91 (13%)
Query: 213 PPPAVTWEKQSHQ---RENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAA 269
P P V+W K + + L M+ D + ++ V + DAG+YT T N
Sbjct: 8042 PVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA--------DAGIYTITLENKL 8093
Query: 270 GLLRADFPLSVVQRE-PARDAAPSIPAPAEC 299
G A + V+ P +D S + C
Sbjct: 8094 GSATASINVKVIGLPGPCKDIKASDITKSSC 8124
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.455
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,750,601
Number of Sequences: 37866
Number of extensions: 1634937
Number of successful extensions: 13635
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 330
Number of HSP's successfully gapped in prelim test: 372
Number of HSP's that attempted gapping in prelim test: 9743
Number of HSP's gapped (non-prelim): 3388
length of query: 548
length of database: 18,247,518
effective HSP length: 107
effective length of query: 441
effective length of database: 14,195,856
effective search space: 6260372496
effective search space used: 6260372496
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.