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Search of human proteins with 167466217
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167466217 integrin alpha L isoform b precursor [Homo
sapiens]
(1086 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 2181 0.0
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 1956 0.0
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 473 e-133
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 472 e-133
gi|34452173 integrin alpha X precursor [Homo sapiens] 463 e-130
gi|62548866 integrin, alpha D precursor [Homo sapiens] 453 e-127
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 328 2e-89
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 328 2e-89
gi|148728188 integrin, alpha E precursor [Homo sapiens] 318 1e-86
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 316 7e-86
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 288 3e-77
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 216 1e-55
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 198 2e-50
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 176 1e-43
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 176 1e-43
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 160 8e-39
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 157 5e-38
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 157 5e-38
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 153 1e-36
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 142 2e-33
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 142 2e-33
gi|49170034 integrin, alpha 8 [Homo sapiens] 141 3e-33
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 140 7e-33
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 123 1e-27
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 123 1e-27
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 120 5e-27
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 110 7e-24
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 70 1e-11
gi|29171717 glycosylphosphatidylinositol specific phospholipase ... 65 5e-10
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 61 5e-09
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 2181 bits (5652), Expect = 0.0
Identities = 1086/1086 (100%), Positives = 1086/1086 (100%)
Query: 1 MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGA 60
MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGA
Sbjct: 1 MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGA 60
Query: 61 PGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILFAAVQFSTSYK 120
PGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILFAAVQFSTSYK
Sbjct: 61 PGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILFAAVQFSTSYK 120
Query: 121 TEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIIT 180
TEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIIT
Sbjct: 121 TEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIIT 180
Query: 181 DGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKLKDL 240
DGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKLKDL
Sbjct: 181 DGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKLKDL 240
Query: 241 FTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWAGGFLDLKAD 300
FTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWAGGFLDLKAD
Sbjct: 241 FTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWAGGFLDLKAD 300
Query: 301 LQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGG 360
LQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGG
Sbjct: 301 LQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGG 360
Query: 361 HWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRVFIYQRRQLG 420
HWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRVFIYQRRQLG
Sbjct: 361 HWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRVFIYQRRQLG 420
Query: 421 FEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSP 480
FEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSP
Sbjct: 421 FEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSP 480
Query: 481 QPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMS 540
QPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMS
Sbjct: 481 QPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMS 540
Query: 541 FSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTR 600
FSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTR
Sbjct: 541 FSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTR 600
Query: 601 RRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQ 660
RRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQ
Sbjct: 601 RRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQ 660
Query: 661 RAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVE 720
RAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVE
Sbjct: 661 RAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVE 720
Query: 721 LSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVS 780
LSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVS
Sbjct: 721 LSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVS 780
Query: 781 SPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPILYPIN 840
SPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPILYPIN
Sbjct: 781 SPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPILYPIN 840
Query: 841 ILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPI 900
ILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPI
Sbjct: 841 ILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPI 900
Query: 901 THQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEILVQVIGTLELVGEIE 960
THQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEILVQVIGTLELVGEIE
Sbjct: 901 THQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEILVQVIGTLELVGEIE 960
Query: 961 ASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQMLYLYVLSGIGGLLLL 1020
ASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQMLYLYVLSGIGGLLLL
Sbjct: 961 ASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQMLYLYVLSGIGGLLLL 1020
Query: 1021 LLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEAGDPGCLKPLHEKDSE 1080
LLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEAGDPGCLKPLHEKDSE
Sbjct: 1021 LLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEAGDPGCLKPLHEKDSE 1080
Query: 1081 SGGGKD 1086
SGGGKD
Sbjct: 1081 SGGGKD 1086
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 1956 bits (5067), Expect = 0.0
Identities = 978/981 (99%), Positives = 978/981 (99%), Gaps = 1/981 (0%)
Query: 107 SILFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREEL 166
S FAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREEL
Sbjct: 190 SYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREEL 249
Query: 167 GARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASE 226
GARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASE
Sbjct: 250 GARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASE 309
Query: 227 FVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVG 286
FVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVG
Sbjct: 310 FVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVG 369
Query: 287 AKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQH 346
AKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQH
Sbjct: 370 AKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQH 429
Query: 347 MGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQ 406
MGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQ
Sbjct: 430 MGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQ 489
Query: 407 RGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQG 466
RGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQG
Sbjct: 490 RGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQG 549
Query: 467 AVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIV 526
AVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIV
Sbjct: 550 AVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIV 609
Query: 527 LSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVA 586
LSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVA
Sbjct: 610 LSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVA 669
Query: 587 NLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSL 646
NLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSL
Sbjct: 670 NLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSL 729
Query: 647 NFSLWEEEGTPRDQRA-GKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPAR 705
NFSLWEEEGTPRDQRA GKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPAR
Sbjct: 730 NFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPAR 789
Query: 706 SRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELP 765
SRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELP
Sbjct: 790 SRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELP 849
Query: 766 EESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLE 825
EESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLE
Sbjct: 850 EESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLE 909
Query: 826 DNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTL 885
DNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTL
Sbjct: 910 DNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTL 969
Query: 886 EAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEI 945
EAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEI
Sbjct: 970 EAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEI 1029
Query: 946 LVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQM 1005
LVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQM
Sbjct: 1030 LVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQM 1089
Query: 1006 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEA 1065
LYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEA
Sbjct: 1090 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEA 1149
Query: 1066 GDPGCLKPLHEKDSESGGGKD 1086
GDPGCLKPLHEKDSESGGGKD
Sbjct: 1150 GDPGCLKPLHEKDSESGGGKD 1170
Score = 225 bits (574), Expect = 2e-58
Identities = 109/109 (100%), Positives = 109/109 (100%)
Query: 1 MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGA 60
MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGA
Sbjct: 1 MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGA 60
Query: 61 PGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSIL 109
PGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSIL
Sbjct: 61 PGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSIL 109
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 473 bits (1217), Expect = e-133
Identities = 340/1033 (32%), Positives = 520/1033 (50%), Gaps = 63/1033 (6%)
Query: 59 GAPGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILFAAVQFSTS 118
G P E + L G+G +P R K T+ LF+ +Q+S
Sbjct: 143 GCPQEDSDIAFLID---GSGSIIPHDFR----RMKEFVSTVMEQLKKSKTLFSLMQYSEE 195
Query: 119 YKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLII 178
++ F F ++ +P +L+K + +L T+T I V E+F GAR +A K+L++
Sbjct: 196 FRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVV 255
Query: 179 ITDGEATDS--GNIDAAKD-----IIRYIIGIGKHFQTKESQETLHKFASKPASEFVKIL 231
ITDGE G D + +IRY+IG+G F++++S++ L+ ASKP + V +
Sbjct: 256 ITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQV 315
Query: 232 DTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWA 291
+ FE LK + +L++KI+ IEGT +SF E+S G SA ++ ++ VG+ DWA
Sbjct: 316 NNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSYDWA 375
Query: 292 GGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVL 351
GG L + TFI + ++ YLGY + R + L GAPRYQH+G V
Sbjct: 376 GGVF-LYTSKEKSTFINMTRVDSDMNDAYLGYAAA-IILRNRVQSLVLGAPRYQHIGLVA 433
Query: 352 LFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRV 411
+F+ Q G W + GTQIG+YFG LC VDVD +G T+L+LIGAP +Y + RGG+V
Sbjct: 434 MFR--QNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQV 491
Query: 412 FI--YQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE--QGA 467
+ R + ++ + L G+ G P GRFG A+T L D+NGD L DVA+GAP EE +GA
Sbjct: 492 SVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGA 551
Query: 468 VYIFNGRHG-GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIV 526
VY+F+G G G+SP SQRI G+++ +Q+FG+S+ G +DL DGL D+ VGA+ +++
Sbjct: 552 VYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLL 611
Query: 527 LSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI-KSLIPQF-QGRL 584
L S+PV+ + +M F+P E+ + EC+ K KE + +C + KS + +G++
Sbjct: 612 LRSQPVLRVKAIMEFNPREVARNVFECNDQVV-KGKEAGEVRVCLHVQKSTRDRLREGQI 670
Query: 585 VANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVT-TSMSCTDFSFHFPVCVQDLISPIN 643
+ +TY L LD R R +F ++ RR V + +C P C++D +SPI
Sbjct: 671 QSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIV 730
Query: 644 VSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSP 703
+ LNFSL GTP G P + + T PFEKNCG D C+ +L ++FS
Sbjct: 731 LRLNFSL---VGTPL-SAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSF 786
Query: 704 ARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEML---KPHSQIPVS 760
L + +V +++ N ED+Y Q+ FP LS+RKV L + ++
Sbjct: 787 MSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLA 846
Query: 761 CEELPE-ESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNE 819
CE E ++ SC+++ PIF V + F+ +S G+ + L ANVT N
Sbjct: 847 CESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN- 905
Query: 820 DSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHD 879
+ +P+ Y + +++ ST Y++FT ++H YQV ++
Sbjct: 906 NMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQV---SNLGQ 962
Query: 880 HNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPV 939
++P + V VP ++ I + V + ERLP ++ L + PV
Sbjct: 963 RSLP-ISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSD--FLAELRKAPV 1019
Query: 940 V------------------FRQEILVQVIGTLELVGEIEAS-SMFSLCSSLSISFNSSKH 980
V ++E + G L I+ S + + S+ I FN S
Sbjct: 1020 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF 1079
Query: 981 FHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKE 1039
L G A + +Q KV+ L L V S +GGLLLL LI LYK+GFFKR K+
Sbjct: 1080 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD 1139
Query: 1040 KMEAGRGVPNGIP 1052
M G G P P
Sbjct: 1140 MMSEG-GPPGAEP 1151
Score = 58.2 bits (139), Expect = 4e-08
Identities = 132/529 (24%), Positives = 213/529 (40%), Gaps = 100/529 (18%)
Query: 26 YNLDVRGARSFSPPRAGRHFGYRVLQV-GNGVIVGAPGE---GNSTGSLYQCQSGTGHCL 81
+NLD A +F G FG V+Q+ G+ V+VGAP E N GSLYQC TG C
Sbjct: 17 FNLDTENAMTFQENARG--FGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQCDYSTGSCE 74
Query: 82 PVTLR-GSNYTSKYLGMTLATDPTDGSILFAAVQFSTSYKTEFDFSDYVKRKDPDALLKH 140
P+ L+ + LG++LA + +L T ++T + + YVK
Sbjct: 75 PIRLQVPVEAVNMSLGLSLAATTSPPQLLACG---PTVHQTCSE-NTYVKG--------- 121
Query: 141 VKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYI 200
L FG+ + F E L P + + DG SG+I
Sbjct: 122 ------LCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDG----SGSI---------- 161
Query: 201 IGIGKHFQTKESQETLHKFASKPASEFVK-ILDTFEKLKDLFTELQ-KKIYVIEGTSKQD 258
H F + EFV +++ +K K LF+ +Q + + I T K+
Sbjct: 162 --------------IPHDF--RRMKEFVSTVMEQLKKSKTLFSLMQYSEEFRIHFTFKEF 205
Query: 259 LTSFNMELSSSGISADLSRGHAVVG-----------AVGAKDWAGGFLDLKADLQD-DTF 306
+ N I+ L R H G GA+ A L + D +
Sbjct: 206 QNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDP 265
Query: 307 IGNEPLTPEV-RAGYLGYTV------TWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGG 359
+G E + PE R G + Y + SRQ+ + +AS PR H+ +V F+ +
Sbjct: 266 LGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPR-DHVFQVNNFEALKTI 324
Query: 360 GHW--SQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFY---GEQRGGRVFIY 414
+ ++ I GTQ GS E ++ Q+G + + PL G VF+Y
Sbjct: 325 QNQLREKIFAIEGTQTGSSSSFE---HEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLY 381
Query: 415 QRRQLG-FEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAP-LEEQGAVYIFN 472
++ F ++ + D + AI I + + + +GAP + G V +F
Sbjct: 382 TSKEKSTFINMTRVDSDMNDAYLGYAAAI-----ILRNRVQSLVLGAPRYQHIGLVAMFR 436
Query: 473 GRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLAD-VAVGA 520
G + + ++GTQ+ + +FG S+ V D++ +G D V +GA
Sbjct: 437 QNTG--MWESNANVKGTQIGA---YFGASLCSV-DVDSNGSTDLVLIGA 479
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 472 bits (1214), Expect = e-133
Identities = 342/1036 (33%), Positives = 520/1036 (50%), Gaps = 68/1036 (6%)
Query: 59 GAPGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILFAAVQFSTS 118
G P E + L G+G +P R K T+ LF+ +Q+S
Sbjct: 143 GCPQEDSDIAFLID---GSGSIIPHDFR----RMKEFVSTVMEQLKKSKTLFSLMQYSEE 195
Query: 119 YKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLII 178
++ F F ++ +P +L+K + +L T+T I V E+F GAR +A K+L++
Sbjct: 196 FRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVV 255
Query: 179 ITDGEATDS--GNIDAAKD-----IIRYIIGIGKHFQTKESQETLHKFASKPASEFVKIL 231
ITDGE G D + +IRY+IG+G F++++S++ L+ ASKP + V +
Sbjct: 256 ITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQV 315
Query: 232 DTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWA 291
+ FE LK + +L++KI+ IEGT +SF E+S G SA ++ ++ VG+ DWA
Sbjct: 316 NNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSYDWA 375
Query: 292 GGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVL 351
GG L + TFI + ++ YLGY + R + L GAPRYQH+G V
Sbjct: 376 GGVF-LYTSKEKSTFINMTRVDSDMNDAYLGYAAA-IILRNRVQSLVLGAPRYQHIGLVA 433
Query: 352 LFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRV 411
+F+ Q G W + GTQIG+YFG LC VDVD +G T+L+LIGAP +Y + RGG+V
Sbjct: 434 MFR--QNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQV 491
Query: 412 FIY-----QRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE-- 464
+ QR + + V L G+ G P GRFG A+T L D+NGD L DVA+GAP EE
Sbjct: 492 SVCPLPRGQRARWQCDAV--LYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDN 549
Query: 465 QGAVYIFNGRHG-GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQ 523
+GAVY+F+G G G+SP SQRI G+++ +Q+FG+S+ G +DL DGL D+ VGA+
Sbjct: 550 RGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH 609
Query: 524 MIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI-KSLIPQF-Q 581
+++L S+PV+ + +M F+P E+ + EC+ K KE + +C + KS + +
Sbjct: 610 VLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVV-KGKEAGEVRVCLHVQKSTRDRLRE 668
Query: 582 GRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVT-TSMSCTDFSFHFPVCVQDLIS 640
G++ + +TY L LD R R +F ++ RR V + +C P C++D +S
Sbjct: 669 GQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVS 728
Query: 641 PINVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVS 700
PI + LNFSL GTP G P + + T PFEKNCG D C+ +L ++
Sbjct: 729 PIVLRLNFSL---VGTPL-SAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSIT 784
Query: 701 FSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEML---KPHSQI 757
FS L + +V +++ N ED+Y Q+ FP LS+RKV L +
Sbjct: 785 FSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSW 844
Query: 758 PVSCEELPE-ESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC 816
++CE E ++ SC+++ PIF V + F+ +S G+ + L ANVT
Sbjct: 845 RLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTS 904
Query: 817 NNEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPS 876
N + +P+ Y + +++ ST Y++FT ++H YQV +
Sbjct: 905 EN-NMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQV---SN 960
Query: 877 IHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFR 936
+ ++P + V VP ++ I + V + ERLP ++ L +
Sbjct: 961 LGQRSLP-ISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSD--FLAELRK 1017
Query: 937 CPVV------------------FRQEILVQVIGTLELVGEIEAS-SMFSLCSSLSISFNS 977
PVV ++E + G L I+ S + + S+ I FN
Sbjct: 1018 APVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFND 1077
Query: 978 SKHFHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRN 1036
S L G A + +Q KV+ L L V S +GGLLLL LI LYK+GFFKR
Sbjct: 1078 SVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQ 1137
Query: 1037 LKEKMEAGRGVPNGIP 1052
K+ M G G P P
Sbjct: 1138 YKDMMSEG-GPPGAEP 1152
Score = 58.2 bits (139), Expect = 4e-08
Identities = 132/529 (24%), Positives = 213/529 (40%), Gaps = 100/529 (18%)
Query: 26 YNLDVRGARSFSPPRAGRHFGYRVLQV-GNGVIVGAPGE---GNSTGSLYQCQSGTGHCL 81
+NLD A +F G FG V+Q+ G+ V+VGAP E N GSLYQC TG C
Sbjct: 17 FNLDTENAMTFQENARG--FGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQCDYSTGSCE 74
Query: 82 PVTLR-GSNYTSKYLGMTLATDPTDGSILFAAVQFSTSYKTEFDFSDYVKRKDPDALLKH 140
P+ L+ + LG++LA + +L T ++T + + YVK
Sbjct: 75 PIRLQVPVEAVNMSLGLSLAATTSPPQLLACG---PTVHQTCSE-NTYVKG--------- 121
Query: 141 VKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYI 200
L FG+ + F E L P + + DG SG+I
Sbjct: 122 ------LCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDG----SGSI---------- 161
Query: 201 IGIGKHFQTKESQETLHKFASKPASEFVK-ILDTFEKLKDLFTELQ-KKIYVIEGTSKQD 258
H F + EFV +++ +K K LF+ +Q + + I T K+
Sbjct: 162 --------------IPHDF--RRMKEFVSTVMEQLKKSKTLFSLMQYSEEFRIHFTFKEF 205
Query: 259 LTSFNMELSSSGISADLSRGHAVVG-----------AVGAKDWAGGFLDLKADLQD-DTF 306
+ N I+ L R H G GA+ A L + D +
Sbjct: 206 QNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDP 265
Query: 307 IGNEPLTPEV-RAGYLGYTV------TWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGG 359
+G E + PE R G + Y + SRQ+ + +AS PR H+ +V F+ +
Sbjct: 266 LGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPR-DHVFQVNNFEALKTI 324
Query: 360 GHW--SQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFY---GEQRGGRVFIY 414
+ ++ I GTQ GS E ++ Q+G + + PL G VF+Y
Sbjct: 325 QNQLREKIFAIEGTQTGSSSSFE---HEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLY 381
Query: 415 QRRQLG-FEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAP-LEEQGAVYIFN 472
++ F ++ + D + AI I + + + +GAP + G V +F
Sbjct: 382 TSKEKSTFINMTRVDSDMNDAYLGYAAAI-----ILRNRVQSLVLGAPRYQHIGLVAMFR 436
Query: 473 GRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLAD-VAVGA 520
G + + ++GTQ+ + +FG S+ V D++ +G D V +GA
Sbjct: 437 QNTG--MWESNANVKGTQIGA---YFGASLCSV-DVDSNGSTDLVLIGA 479
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 463 bits (1192), Expect = e-130
Identities = 346/990 (34%), Positives = 505/990 (51%), Gaps = 78/990 (7%)
Query: 107 SILFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREEL 166
S F+ +QFS ++T F F ++ + +P +LL V + T T AI V +F
Sbjct: 185 STQFSLMQFSNKFQTHFTFEEFRRSSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHASY 244
Query: 167 GARPDATKVLIIITDGEATDSGNIDA--------AKDIIRYIIGIGKHFQTKESQETLHK 218
GAR DA K+LI+ITDG+ + ++D A IIRY IG+G FQ + S + L+
Sbjct: 245 GARRDAAKILIVITDGKK-EGDSLDYKDVIPMADAAGIIRYAIGVGLAFQNRNSWKELND 303
Query: 219 FASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRG 278
ASKP+ E + ++ F+ LKD+ +L++KI+ IEGT +SF +E++ G SA +
Sbjct: 304 IASKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFSAVFTPD 363
Query: 279 HAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLA 338
V+GAVG+ W+GG L TFI ++R YLGY+ T L + L
Sbjct: 364 GPVLGAVGSFTWSGGAF-LYPPNMSPTFINMSQENVDMRDSYLGYS-TELALWKGVQSLV 421
Query: 339 SGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIG 398
GAPRYQH G+ ++F Q W + GTQIGSYFG LC VDVD DG T+L+LIG
Sbjct: 422 LGAPRYQHTGKAVIF--TQVSRQWRMKAEVTGTQIGSYFGASLCSVDVDSDGSTDLVLIG 479
Query: 399 APLFYGEQRGGRVFI--YQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDV 456
AP +Y + RGG+V + R + + L G+ G+P GRFG A+T L D+NGD L DV
Sbjct: 480 APHYYEQTRGGQVSVCPLPRGWRRWWCDAVLYGEQGHPWGRFGAALTVLGDVNGDKLTDV 539
Query: 457 AVGAPLEEQ--GAVYIFNGRHG-GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGL 513
+GAP EE+ GAVY+F+G G +SP SQRI G+Q+ S +Q+FG+++ G +DL DGL
Sbjct: 540 VIGAPGEEENRGAVYLFHGVLGPSISPSHSQRIAGSQLSSRLQYFGQALSGGQDLTQDGL 599
Query: 514 ADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI 573
D+AVGA Q+++L +RPV+ + M F PAEIP EC ++ + V IC I
Sbjct: 600 VDLAVGARGQVLLLRTRPVLWVGVSMQFIPAEIPRSAFECREQVVSE-QTLVQSNICLYI 658
Query: 574 KSLIPQFQGR--LVANLTYTLQLDGHRTRRRGLFPGGRH-ELRRNIAVTTSMSCTDFSFH 630
G L +++T L LD R R F ++ L R + C +F+
Sbjct: 659 DKRSKNLLGSRDLQSSVTLDLALDPGRLSPRATFQETKNRSLSRVRVLGLKAHCENFNLL 718
Query: 631 FPVCVQDLISPINVSLNFSLWEEEGTPRDQRAGKDIPPI--LRPSLHSE-----TWEIPF 683
P CV+D ++PI + LNF+L GK + LRP L ++ T +PF
Sbjct: 719 LPSCVEDSVTPITLRLNFTL-----------VGKPLLAFRNLRPMLAADAQRYFTASLPF 767
Query: 684 EKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGL 743
EKNCG D C+ NL +SFS ++L + + L+ E+ + N ED+Y + P GL
Sbjct: 768 EKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGL 827
Query: 744 SFRKVEMLKPHSQ---IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLV 800
S+R V + Q + ++C+ P S+ + + SC ++ IF+ G + F+
Sbjct: 828 SYRYVAEGQKQGQLRSLHLTCDSAPVGSQ-GTWSTSCRINHLIFRGGAQITFLATFDVSP 886
Query: 801 NSSWGDSVELHANVTCNNEDSDLLEDNSATTI---IPILYPINILIQDQEDSTLYVSFTP 857
+ GD + L ANV+ N S TT +P+ Y + ++ E T Y++F+
Sbjct: 887 KAVLGDRLLLTANVSSENN----TPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSE 942
Query: 858 KGPK-IHQVKHMYQV-----RIQPSIHDHNIPT--------LEAVVGVPQPPSEGPITHQ 903
K H H YQV R P + +P ++ V PQ PS
Sbjct: 943 SEEKESHVAMHRYQVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSHPQNPS----LRC 998
Query: 904 WSVQMEPPVPCHYEDLERLPDAAEPCLPGAL-FRCPV---VFRQEILVQVIGTLEL--VG 957
S ++ PP +++ P + + G L FRC V ++E+ + G L V
Sbjct: 999 SSEKIAPPASDFLAHIQKNP-VLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVR 1057
Query: 958 EIEASSMFSLCSSLSISFNSSKHFHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGG 1016
+I S+ S I+F++S + L G A + AQ ++ L V S IGG
Sbjct: 1058 QI-LQKKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGG 1116
Query: 1017 LLLLLLIFIVLYKVGFFKRNLKEKMEAGRG 1046
LLLL LI VLYKVGFFKR KE ME G
Sbjct: 1117 LLLLALITAVLYKVGFFKRQYKEMMEEANG 1146
Score = 49.3 bits (116), Expect = 2e-05
Identities = 37/103 (35%), Positives = 51/103 (49%), Gaps = 7/103 (6%)
Query: 12 ALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNG-VIVGAPGE---GNST 67
A L F A + +NLD +F AG FG V+Q N V+VGAP + N T
Sbjct: 6 AALLLFTALATSLGFNLDTEELTAFRVDSAG--FGDSVVQYANSWVVVGAPQKITAANQT 63
Query: 68 GSLYQCQSGTGHCLPVTLR-GSNYTSKYLGMTLATDPTDGSIL 109
G LYQC TG C P+ L+ + LG++LA+ + +L
Sbjct: 64 GGLYQCGYSTGACEPIGLQVPPEAVNMSLGLSLASTTSPSQLL 106
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 453 bits (1166), Expect = e-127
Identities = 331/973 (34%), Positives = 513/973 (52%), Gaps = 60/973 (6%)
Query: 109 LFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGA 168
LFA +Q+S K F F+ + +L+ + + LT T I V T++F + GA
Sbjct: 186 LFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNGA 245
Query: 169 RPDATKVLIIITDGEATD-----SGNIDAAKD--IIRYIIGIGKHFQTKESQETLHKFAS 221
R A K+LI+ITDG+ S I A+ IIRY IG+G FQ +++ L+ +S
Sbjct: 246 RKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGPTARQELNTISS 305
Query: 222 KPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAV 281
P + V +D F L + +LQ+KIY +EGT + +SF E+S G S L+
Sbjct: 306 APPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFSTALTMDGLF 365
Query: 282 VGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGA 341
+GAVG+ W+GG L TFI ++R YLGY+ T L + L GA
Sbjct: 366 LGAVGSFSWSGGAF-LYPPNMSPTFINMSQENVDMRDSYLGYS-TELALWKGVQNLVLGA 423
Query: 342 PRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPL 401
PRYQH G+ ++F Q W + + GTQIGSYFG LC VDVD DG T+L+LIGAP
Sbjct: 424 PRYQHTGKAVIF--TQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPH 481
Query: 402 FYGEQRGGRVFI--YQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVG 459
+Y + RGG+V + R ++ ++ + L+G+ G+P GRFG A+T L D+N D L+DVA+G
Sbjct: 482 YYEQTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIG 541
Query: 460 APLEEQ--GAVYIFNG-RHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADV 516
AP E++ GAVY+F+G G+SP SQRI +Q+ +Q+FG+++ G +DL DGL D+
Sbjct: 542 APGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDL 601
Query: 517 AVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSL 576
AVGA Q+++L S PV+ + M FSP E+ C + ++ G + T+C I+
Sbjct: 602 AVGARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAG-DATVCLTIQKS 660
Query: 577 IPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRH-ELRRNIAVTTSMSCTDFSFHFPVCV 635
G + +++ + L LD R R +F ++ L R + + C P CV
Sbjct: 661 SLDQLGDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCV 720
Query: 636 QDLISPINVSLNFSLWEEE-GTPRDQRAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCE 694
+D++SPI + LNFSL E +P++ R P + S T +PFEKNCG+D CE
Sbjct: 721 EDVVSPIILHLNFSLVREPIPSPQNLR-----PVLAVGSQDLFTASLPFEKNCGQDGLCE 775
Query: 695 ANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVE--MLK 752
+L V+ S + + L + + L+V +++ N ED+Y + L++P GLS R+V +
Sbjct: 776 GDLGVTLSFSGLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQ 835
Query: 753 PH-SQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELH 811
PH S + ++CE +P E L R+ C+V+ PIF G + + F+ ++ GD + +
Sbjct: 836 PHQSALRLACETVPTEDEGL-RSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMR 894
Query: 812 ANVTCNNEDSDLLEDNSATTI---IPILYPINILIQDQEDSTLYVSF-TPKGPKIHQVKH 867
A+ + N + +S T +P+ Y + +I QE+ST Y +F T K+ + +H
Sbjct: 895 ASASSENNKA----SSSKATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEH 950
Query: 868 MYQVR------IQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLER 921
Y+V + SI + +P L V V E P V P P H + L +
Sbjct: 951 RYRVNNLSQRDLAISI-NFWVPVLLNGVAVWDVVMEAPSQSLPCVSERKP-PQHSDFLTQ 1008
Query: 922 LPDAAEPCLPGAL-----FRCPV---VFRQEILVQVIGTLELVGEIEASSMFSLCSSLS- 972
+ + P L ++ FRC V ++E+ + G L E L S++
Sbjct: 1009 I--SRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAE 1066
Query: 973 ISFNSSKHFHLYGSNASL---AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYK 1029
I+F++S + L G A + ++V++ D VY + + + S +G LLLL LI LYK
Sbjct: 1067 ITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVY--NAIPIIMGSSVGALLLLALITATLYK 1124
Query: 1030 VGFFKRNLKEKME 1042
+GFFKR+ KE +E
Sbjct: 1125 LGFFKRHYKEMLE 1137
Score = 51.6 bits (122), Expect = 4e-06
Identities = 41/110 (37%), Positives = 55/110 (50%), Gaps = 14/110 (12%)
Query: 7 TVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNG-VIVGAPGE-- 63
TV+ +++L+ + F NLDV F G FG V+Q G ++VGAP E
Sbjct: 5 TVLLLSVLASYHGF------NLDVEEPTIFQEDAGG--FGQSVVQFGGSRLVVGAPLEVV 56
Query: 64 -GNSTGSLYQCQSGTGHCLPVTLR-GSNYTSKYLGMTLATDPTDGSILFA 111
N TG LY C + TG C P+ L + LG+TLA T+GS L A
Sbjct: 57 AANQTGRLYDCAAATGMCQPIPLHIRPEAVNMSLGLTLAAS-TNGSRLLA 105
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 328 bits (841), Expect = 2e-89
Identities = 298/1022 (29%), Positives = 471/1022 (46%), Gaps = 122/1022 (11%)
Query: 106 GSILFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHML-LLTNTFGAINYVATEVFRE 164
G I VQ+ EF +DY KD H++ T T I + +E F++
Sbjct: 197 GQIQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQK 256
Query: 165 ELGARPDATKVLIIITDGEATDSGNIDAA------KDIIRYIIGIGKHFQTKE-SQET-- 215
G R A KV+I+ITDGE+ DS +++ ++ RY + + ++ + + ET
Sbjct: 257 --GGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFL 314
Query: 216 --LHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISA 273
+ AS P + + LKD+ L +I+ +EGT+K + TSF +E+S +G S+
Sbjct: 315 NEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNKNE-TSFGLEMSQTGFSS 373
Query: 274 DLSRGHAVVGAVGAKDWAGGFLDL----KADLQDDTFIGNEPLTPEVRAGYLGYTVTWLP 329
+ ++GAVGA DW G L K ++++ P + YLGYTVT +
Sbjct: 374 HVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVV 433
Query: 330 SRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIH----GTQIGSYFGGELCGVD 385
S ++ + +GAPR+ H G+V+LF H ++ TIH G QIGSYFG E+ VD
Sbjct: 434 SSRQGRVYVAGAPRFNHTGKVILFTM-----HNNRSLTIHQAMRGQQIGSYFGSEITSVD 488
Query: 386 VDQDGETELLLIGAPLFYGEQRG-GRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITA 444
+D DG T++LL+GAP+++ E R G+V++Y+ RQ F L+ Y RFG +I +
Sbjct: 489 IDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNGTLKDSHSYQNARFGSSIAS 548
Query: 445 LTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSI 502
+ D+N D DV VGAPLE+ GA+YIF+G G + P QRI +++ +G+Q+FG SI
Sbjct: 549 VRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSI 608
Query: 503 HGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMK 562
HG DL DGL D+AVGA ++L SRPVV + + F P++I + +C S +
Sbjct: 609 HGQLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFHRDC--KRSGRDA 666
Query: 563 EGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHR-TRRRGLFPGGRHELRRNIAVTTS 621
+ +CF L P FQ V + Y +D R T R L GG R + +++
Sbjct: 667 TCLAAFLCFTPIFLAPHFQTTTV-GIRYNATMDERRYTPRAHLDEGGDRFTNRAVLLSSG 725
Query: 622 MS-CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWE 680
C +FH + D + P+ S+ +SL + + P P LR S
Sbjct: 726 QELCERINFHV-LDTADYVKPVTFSVEYSLEDPDHGP---MLDDGWPTTLRVS------- 774
Query: 681 IPFEKNCGEDKKCEANL----------------RVSFSPARSRALRLTAFAS-------- 716
+PF C ED+ C +L RV PA+ + +F +
Sbjct: 775 VPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIEST 834
Query: 717 ---LSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSR 773
++VE +L N E+AY L++ L F + + K S + C + EE RL +
Sbjct: 835 RQRVAVEATLENRGENAYSTVLNISQSANLQFASL-IQKEDSDGSIEC--VNEERRLQKQ 891
Query: 774 ALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELH------ANVTCNNEDSDLLEDN 827
CNVS P F+A VA ++ F + S+ LH A + +NE EDN
Sbjct: 892 V--CNVSYPFFRAKAKVAFRLDF------EFSKSIFLHHLEIELAAGSDSNERDSTKEDN 943
Query: 828 SATTIIPILYPINIL-----------IQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPS 876
A + Y ++L ++ Y P I +++++ I
Sbjct: 944 VAPLRFHLKYEADVLFTRSSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGM 1003
Query: 877 IHDHNIPTLEAVVGVPQPPSEGPITHQ-------WSVQME-PPVPCHYEDLERLPDAAEP 928
+ IP + G +T + W E P P EDL R P
Sbjct: 1004 MMKITIP-IATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVE-EDLRRAPQLNHS 1061
Query: 929 CLPGALFRCPV--VFRQEILVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFH---L 983
C + V QEI ++G L L ++A S+ + ++ + FH +
Sbjct: 1062 NSDVVSINCNIRLVPNQEINFHLLGNLWL-RSLKALKYKSM--KIMVNAALQRQFHSPFI 1118
Query: 984 YGSNASLAQVVMKVDVVYEKQM-LYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKME 1042
+ Q+V ++ + Q+ +++ V S +GGLLLL L+ + L+K+GFF R+ + + E
Sbjct: 1119 FREEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFF-RSARRRRE 1177
Query: 1043 AG 1044
G
Sbjct: 1178 PG 1179
Score = 44.3 bits (103), Expect = 6e-04
Identities = 40/118 (33%), Positives = 57/118 (48%), Gaps = 20/118 (16%)
Query: 6 ITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQ---VGNG-VIVGAP 61
+ A++L GF ++N+D R R R FGY V Q GN ++VGAP
Sbjct: 8 VVAWALSLWPGF-----TDTFNMDTRKPRVIPGSRTA-FFGYTVQQHDISGNKWLVVGAP 61
Query: 62 GEGNS---TGSLYQCQSGTGHCLPVTLRG---SNYTSKY----LGMTLATDPTDGSIL 109
E N TG +Y+C G+C + L SN + + LG++LAT+P D S L
Sbjct: 62 LETNGYQKTGDVYKCPVIHGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFL 119
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 328 bits (840), Expect = 2e-89
Identities = 280/1006 (27%), Positives = 467/1006 (46%), Gaps = 115/1006 (11%)
Query: 113 VQFSTSYKTEFDFSDYVKRKDP-DALLKHVKHMLLLTNTFGAINYVATEVFREELGARPD 171
VQ+ + EF+ + Y ++ A K V+ T T I+ E F E GAR
Sbjct: 212 VQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRG 271
Query: 172 ATKVLIIITDGEATDSGNIDAA------KDIIRYIIGI-----GKHFQTKESQETLHKFA 220
KV++I+TDGE+ D+ + ++I R+ I I + T++ E + A
Sbjct: 272 VKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIA 331
Query: 221 SKPASE-FVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGH 279
S+P + F + D L + L ++I+ +E T+ Q SF ME+S +G SA S+
Sbjct: 332 SEPTEKHFFNVSDELA-LVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQDW 390
Query: 280 AVVGAVGAKDWAGGFLDLKADL----QDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTS 335
++GAVGA DW G + KA ++ TF E A YLGYTV +
Sbjct: 391 VMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSGDV 450
Query: 336 LLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELL 395
L +G PRY H G+V++++ G + +QT+ G QIGSYFG L D+D+D T++L
Sbjct: 451 LYIAGQPRYNHTGQVIIYRMEDG--NIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDIL 508
Query: 396 LIGAPLFYGEQRG--GRVFIYQRRQLGFEEVSELQG-----------------DPGYPLG 436
L+GAP++ G ++ G+V++Y Q FE L+ + P G
Sbjct: 509 LVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCG 568
Query: 437 -RFGEAITALTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPSQRIEGTQVLS 493
RFG AI A+ D+N DG D+ +GAPLE+ GAVYI++G + + +QRI
Sbjct: 569 ARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGK 628
Query: 494 GIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVEC 553
+++FG+SIHG DL GDGL DV +G + SR V + M+F P ++ + + C
Sbjct: 629 TLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNC 688
Query: 554 SYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGR-HEL 612
K +N T+CF +K L + A+L Y + LD R R F G + ++
Sbjct: 689 --HMEGKETVCINATVCFDVK-LKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERKV 745
Query: 613 RRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAGKDIPPILRP 672
+RNI V S CT SF+ + D + ++L+F+L + E P+L
Sbjct: 746 QRNITVRKS-ECTKHSFYM-LDKHDFQDSVRITLDFNLTDPEN-----------GPVLDD 792
Query: 673 SLHSETWE-IPFEKNCGEDKKCEANLRVSFSPARSRALRL-TAFASLSVELSLSNLEEDA 730
SL + E IPF K+CG +KC ++L + + L + + +V L++ N ++ A
Sbjct: 793 SLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSA 852
Query: 731 YWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSV 790
Y + +H+ P L F +E ++ SCE + ++C V P + G V
Sbjct: 853 YNTRTIVHYSPNLVFSGIEAIQKD-----SCES--------NHNITCKVGYPFLRRGEMV 899
Query: 791 ALQMMFNTLVNSSW-GDSVELHANVTCNNED-SDLLEDNSATTIIPILYPINI-LIQDQE 847
+++F N+S+ ++V ++ + T ++E+ + L DN IP+ Y + +
Sbjct: 900 TFKILFQ--FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSAS 957
Query: 848 DSTLYVSFTPKGPKI--------HQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEG- 898
+ + ++ P++ +++ Y +R S +P L+ + P S G
Sbjct: 958 EYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF---PMPELKLSISFPNMTSNGY 1014
Query: 899 PITHQWSVQMEPPVPCH---YEDL------ERLPDAAEPCLPGALFRCPVVFRQEILVQV 949
P+ + + C +ED +++ + + G + C I +
Sbjct: 1015 PVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATITCNL 1074
Query: 950 IGTLELVGEIEASSMF---SLCSSLSISFNSSKHFHLYGSNASLA----------QVVMK 996
T + ++ S + + S S N + L NASL + +
Sbjct: 1075 --TSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQIS 1132
Query: 997 VDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKME 1042
D + + L++ +LS GLLLL+L+ + L+K+GFFKR LK+KME
Sbjct: 1133 KDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKME 1178
Score = 57.0 bits (136), Expect = 9e-08
Identities = 133/588 (22%), Positives = 216/588 (36%), Gaps = 114/588 (19%)
Query: 25 SYNLDVRGARSFSPPRAGRHFGYRVLQV----GNGVIVGAPGEG---NSTGSLYQCQSGT 77
S+N+DV+ + +FS P FGY V Q G V++G+P G N TG +Y+C G
Sbjct: 28 SFNVDVKNSMTFSGPVEDM-FGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGR 86
Query: 78 GHC-------LPVTLRGSNYT----SKYLGMTLATDPTDGSI----LFAAVQFSTSYKTE 122
G LPV N T + G TL T+P G + L+A Y T
Sbjct: 87 GESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTG 146
Query: 123 F--DFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYV----ATEVFREELGARPDATKVL 176
D S + + A ++ L + N + + F +L R D
Sbjct: 147 ICSDVSPTFQVVNSIAPVQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLERMD----- 201
Query: 177 IIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEK 236
+ T G + ++ + + + K+ T+E K + + + L
Sbjct: 202 ---IGPKQTQVGIVQYGEN-VTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTA 257
Query: 237 LKDLFTELQ------KKIYVI--EGTSK---------QDLTSFNMELSSSGISADLSRGH 279
K+ FTE + KK+ VI +G S QD N++ S I +RG+
Sbjct: 258 RKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGN 317
Query: 280 -------AVVGAVGAKDWAGGFLDLKADLQDDTFI--------------GNEPLTPEVRA 318
+ ++ ++ F ++ +L T + + E+
Sbjct: 318 LSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEM 377
Query: 319 GYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQ----GGGHWSQVQTIHGTQIG 374
G++ + S+ L A GA Y G V++ + Q ++ T +
Sbjct: 378 SQTGFSAHY--SQDWVMLGAVGA--YDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLA 433
Query: 375 SYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRVFIYQRRQLGFEEVSELQGDPGYP 434
SY G + G+ L + G P + G+V IY+ + + L G+
Sbjct: 434 SYLGYTVNSATA-SSGDV-LYIAGQPRY---NHTGQVIIYRMEDGNIKILQTLSGE---Q 485
Query: 435 LGRFGEAITALTDINGDGLVDV-AVGAPL------EEQGAVYIFNGRHGGLSPQPSQRIE 487
+G + +I TDI+ D D+ VGAP+ EEQG VY++ Q S
Sbjct: 486 IGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPI 545
Query: 488 GTQVLSGIQW---------------FGRSIHGVKDLEGDGLADVAVGA 520
S Q FG +I VKDL DG D+ +GA
Sbjct: 546 KQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGA 593
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 318 bits (816), Expect = 1e-86
Identities = 274/978 (28%), Positives = 446/978 (45%), Gaps = 108/978 (11%)
Query: 110 FAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGAR 169
FA VQ+ +TEFD D A ++++ + +T T A+ +V +F G+R
Sbjct: 241 FALVQYGGVIQTEFDLRDSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSR 300
Query: 170 PDATKVLIIITDG-------EATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASK 222
A+KV++++TDG T N + + R+ IG+G+ F++ + L+ AS
Sbjct: 301 RKASKVMVVLTDGGIFEDPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASD 360
Query: 223 PASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISAD-LSRGHAV 281
P + + L L ++L+ I +EGT L + +L+ G SA L +
Sbjct: 361 PDETHAFKVTNYMALDGLLSKLRYNIISMEGTVGDAL---HYQLAQIGFSAQILDERQVL 417
Query: 282 VGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPE----VRAGYLGYTVTWLPSRQKTSLL 337
+GAVGA DW+GG L + F+ + YLGY V L S +
Sbjct: 418 LGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYI 477
Query: 338 ASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLI 397
A GAPRY+H G V F+ + G S + + G Q+GSYFG ELC VD+D DG T+ LL+
Sbjct: 478 A-GAPRYKHHGAV--FELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLV 534
Query: 398 GAPLFYGEQRGGRVFIYQRRQL--GFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVD 455
AP ++ GRV++Y+ + F L G PG+ RFG A+ A+ D++ D L D
Sbjct: 535 AAPFYHVHGEEGRVYVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTD 594
Query: 456 VAVGAPLEEQGA--------VYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKD 507
VA+GAPLE GA VYI+NG GLS PSQRI + V G+Q+FG S+ G D
Sbjct: 595 VAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFD 654
Query: 508 LEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNI 567
+ GDGLAD+ VG Q +V SRPVV + M+F+P+ +P+ VN+
Sbjct: 655 ISGDGLADITVGTLGQAVVFRSRPVVRLKVSMAFTPSALPI-----------GFNGVVNV 703
Query: 568 TICFQIKSLIPQFQ-GRLVANLTYTLQLDGHRTRRRGLFPGGRHELR-RNIAVTTSMSCT 625
+CF+I S+ + G A L +TL +D + RRR R L + S C
Sbjct: 704 RLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCE 763
Query: 626 DFSF---HFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWEIP 682
D +C +D S +V +++ L EG + P + R + +++P
Sbjct: 764 DLLLMPTEGELCEEDCFSNASVKVSYQLQTPEG-----QTDHPQPILDRYTEPFAIFQLP 818
Query: 683 FEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPG 742
+EK C C A L+++ + + L + L++ ++L+N ED+Y + L++P
Sbjct: 819 YEKACKNKLFCVAELQLA-TTVSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRN 877
Query: 743 LSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFK---AGHSVALQMMFNTL 799
L ++ M KP S + C++ + +L ++C + P+ K A SV Q+ N
Sbjct: 878 LQLKR--MQKPPSP-NIQCDDPQPVASVL--IMNCRIGHPVLKRSSAHVSVVWQLEENAF 932
Query: 800 VNSSWGDSVELHANVTCNNEDSDLLEDNSATT----IIPILYPINILIQDQEDSTLY--- 852
N + ++ VT +NE L + + +L +I+ + +
Sbjct: 933 PNR----TADITVTVTNSNERRSLANETHTLQFRHGFVAVLSKPSIMYVNTGQGLSHHKE 988
Query: 853 VSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPV 912
F G + ++ Q+ + + L+ V ++ WS +
Sbjct: 989 FLFHVHGENLFGAEYQLQICVPTKLRG-----LQVVAVKKLTRTQASTVCTWSQER---- 1039
Query: 913 PCHYEDLERLPDAAEPCLPGALFRCPVVFRQEI-------LVQVIGTLELVGEIEASSMF 965
C Y ++ + + A + V EI L++ + L+++GE
Sbjct: 1040 ACAYSSVQHVEEWHSVSCVIASDKENVTVAAEISWDHSEELLKDVTELQILGE------- 1092
Query: 966 SLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQMLY----LYVLSGIGGLLLLL 1021
ISFN S + L N K+ VV+ K Y + + +GGLL+L+
Sbjct: 1093 -------ISFNKSLYEGLNAENHR-----TKITVVFLKDEKYHSLPIIIKGSVGGLLVLI 1140
Query: 1022 LIFIVLYKVGFFKRNLKE 1039
+I ++L+K GFFKR ++
Sbjct: 1141 VILVILFKCGFFKRKYQQ 1158
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 316 bits (810), Expect = 7e-86
Identities = 286/986 (29%), Positives = 450/986 (45%), Gaps = 107/986 (10%)
Query: 113 VQFSTSYKTEFDFSDYVKRKDPDALLKHVKHML-LLTNTFGAINYVATEVFREELGARPD 171
VQ+ S E+ D+ +++ K++ T T AI TE F + G RP+
Sbjct: 207 VQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPE 266
Query: 172 ATKVLIIITDGEATDSGNIDAAKD------IIRYIIGIGKHFQTKESQET-----LHKFA 220
A ++L+++TDGE+ D + AA + RY I + H+ ++ + + A
Sbjct: 267 AARLLVVVTDGESHDGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIA 326
Query: 221 SKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHA 280
S P F + L D+ L +I+ +EG+ ++ +SF +E+S G S +
Sbjct: 327 SDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFSTHRLKDGI 386
Query: 281 VVGAVGAKDWAGGFLDLKADLQ--------DDTFIGNEPLTPEVRAGYLGYTVTWLPSRQ 332
+ G VGA DW G L L+ + +D F P + A YLGY+V+ + R
Sbjct: 387 LFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEF----PPALQNHAAYLGYSVSSMLLRG 442
Query: 333 KTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGET 392
L SGAPR++H G+V+ FQ + G Q++ G QIGSYFG ELC +D D+DG T
Sbjct: 443 GRRLFLSGAPRFRHRGKVIAFQLKKDGAV-RVAQSLQGEQIGSYFGSELCPLDTDRDGTT 501
Query: 393 ELLLIGAPLFYGEQRG--GRVFIYQRRQLGFEEVSELQG--DPGYPL-GRFGEAITALTD 447
++LL+ AP+F G Q GRV++Y +G + + LQG P P RFG A+ AL D
Sbjct: 502 DVLLVAAPMFLGPQNKETGRVYVYL---VGQQSLLTLQGTLQPEPPQDARFGFAMGALPD 558
Query: 448 INGDGLVDVAVGAPLEE--QGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGV 505
+N DG DVAVGAPLE+ QGA+Y+++G G+ P P+QRI + + +FGRS+ G
Sbjct: 559 LNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGRSVDGR 618
Query: 506 KDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGV 565
DL+GD L DVAVGA+ I+LSSRP+V + + +P I V + +C + +E V
Sbjct: 619 LDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISVVQRDC----RRRGQEAV 674
Query: 566 NIT--ICFQIKSLIP-----QFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHEL--RRNI 616
+T +CFQ+ S P QF R +T LD R F G L RR
Sbjct: 675 CLTAALCFQVTSRTPGRWDHQFYMR------FTASLDEWTAGARAAFDGSGQRLSPRRLR 728
Query: 617 AVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHS 676
+++C FH + D + P+ +++ F+L K P + S S
Sbjct: 729 LSVGNVTCEQLHFHV-LDTSDYLRPVALTVTFAL---------DNTTKPGPVLNEGSPTS 778
Query: 677 ETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFA------SLSVELSLSNLEEDA 730
+PF K+CG D +C +L + + R R F + V +L N +E+A
Sbjct: 779 IQKLVPFSKDCGPDNECVTDLVLQVN-MDIRGSRKAPFVVRGGRRKVLVSTTLENRKENA 837
Query: 731 YWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSV 790
Y L L F L + + S I V C +RL C+V P+F+ G V
Sbjct: 838 YNTSLSLIFSRNLHLASLTPQR-ESPIKVECAAPSAHARL------CSVGHPVFQTGAKV 890
Query: 791 ALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPILYPINILIQDQED-- 848
+ F +S + + E + L+DN+A T I Y ++L +
Sbjct: 891 TFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLH 950
Query: 849 -------STLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTL----EAVVGVPQPPSE 897
TL V P+ +V+++ + I +P + + + Q +
Sbjct: 951 RYEVHPYGTLPVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITN 1010
Query: 898 GPITHQWSVQMEPPVPCHYEDLE---RLPDAAEPCLPGALFRCPVVFRQEILVQVIGTLE 954
++ P P H E+L+ RL + C + RC + + +G L
Sbjct: 1011 NASCIVQNLTEPPGPPVHPEELQHTNRLNGSNTQC---QVVRCHLGQLAKGTEVSVGLLR 1067
Query: 955 LV-GEIEASSMF---SLCSSLSISFNSSKHFHLYGS---NASLAQVVMKVDVVYEKQMLY 1007
LV E + F ++ S+ + L + + SL +VV ++ L+
Sbjct: 1068 LVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEVVQTRPILIS---LW 1124
Query: 1008 LYVLSGIGGLLLLLLIFIVLYKVGFF 1033
+ + S +GGLLLL L+ L+K+GFF
Sbjct: 1125 ILIGSVLGGLLLLALLVFCLWKLGFF 1150
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 288 bits (736), Expect = 3e-77
Identities = 273/967 (28%), Positives = 446/967 (46%), Gaps = 121/967 (12%)
Query: 147 LTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKD------IIRYI 200
LTNTFGAI Y + G R ATKV++++TDGE+ D + A D I+R+
Sbjct: 249 LTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFG 308
Query: 201 IGIGKHFQ-----TKESQETLHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTS 255
I + + TK + + AS P + + L + L ++I+ IEGT
Sbjct: 309 IAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTV 368
Query: 256 KQDLTSFNMELSSSGISADLSRGHAVV--GAVGAKDWAGGFLDLKAD----LQDDTFIGN 309
Q +F ME+S G SAD S + ++ GAVGA W+G + + F +
Sbjct: 369 -QGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAF--D 425
Query: 310 EPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIH 369
+ L + YLGY+V + + + T +A GAPR + G+++L+ + G + + +Q
Sbjct: 426 QILQDRNHSSYLGYSVAAISTGESTHFVA-GAPRANYTGQIVLYSVNENG-NITVIQAHR 483
Query: 370 GTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE--QRGGRVFIYQRRQLGFEEVSEL 427
G QIGSYFG LC VDVD+D T++LL+GAP++ + + GRV+++ ++ + L
Sbjct: 484 GDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQFL 543
Query: 428 QGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPSQR 485
+G G RFG AI AL+DIN DG DV VG+PLE Q GAVYI+NG G + + SQ+
Sbjct: 544 EGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQK 603
Query: 486 IEGTQ--VLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSP 543
I G+ S +Q+FGRS+ G DL GD + DV++GA Q++ L S+ + D+ SF+P
Sbjct: 604 ILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTP 663
Query: 544 AEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTR--R 601
+I + NK + + + +CF K + ++ TL DG +R
Sbjct: 664 EKI---------TLVNKNAQ-IILKLCFSAKFRPTKQNNQVAIVYNITLDADGFSSRVTS 713
Query: 602 RGLFPGGRHE-LRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQ 660
RGLF L++N+ V + SC + + D+++ +++ ++ SL E GT
Sbjct: 714 RGLFKENNERCLQKNMVVNQAQSCPEHIIYIQE-PSDVVNSLDLRVDISL-ENPGTS--- 768
Query: 661 RAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEAN--LRVSFSPARSRALRLTAFAS-- 716
P + S ++ + IPF K+CGED C ++ L V PA + + +
Sbjct: 769 ------PALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKR 822
Query: 717 LSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALS 776
L+ ++L N E AY + + F L F +PV E+ + ++++
Sbjct: 823 LTFSVTLKNKRESAYNTGIVVDFSENLFFASF-------SLPVDGTEVTCQVAASQKSVA 875
Query: 777 CNVSSPIFKAGHSVALQMMFN-TLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPI 835
C+V P K V + F+ L N S+ A E+ DN IP+
Sbjct: 876 CDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEENK---ADNLVNLKIPL 932
Query: 836 LYPINI------------LIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIP 883
LY I + D ++ SF GPK ++ +++ ++
Sbjct: 933 LYDAEIHLTRSTNINFYEISSDGNVPSIVHSFEDVGPKF-----IFSLKVTTGSVPVSMA 987
Query: 884 TLEAVVGVPQPPSE-GPITHQWSVQMEP--PVPC---------------------HYEDL 919
T+ ++ +PQ E P+ + VQ + + C ++
Sbjct: 988 TV--IIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHT 1045
Query: 920 ERLPDAAEPCLPGALFRCPVVFRQEILVQVIGTLELVGEIEASSMF---SLCSSLSISFN 976
+ L C + V + E V V T + ASS F L ++ I+
Sbjct: 1046 KELNCRTASCSNVTCWLKDVHMKGEYFVNV--TTRIWNGTFASSTFQTVQLTAAAEINTY 1103
Query: 977 SSKHFHLYGSNASLAQVVMKVDVVYEKQMLYLYVLSG--IGGLLLLLLIFIVLYKVGFFK 1034
+ + + + + ++ ++MK D EK + V+ G I G+LLLL + +L+K+GFFK
Sbjct: 1104 NPEIYVIEDNTVTIPLMIMKPD---EKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFK 1160
Query: 1035 RNLKEKM 1041
R EKM
Sbjct: 1161 RKY-EKM 1166
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 216 bits (549), Expect = 1e-55
Identities = 186/615 (30%), Positives = 303/615 (49%), Gaps = 57/615 (9%)
Query: 269 SGISADLSRGHAVVGAVGAKDWAGGFLDLKADLQDDTFIG-NEPLTPEVRAGYLGYTVTW 327
+GI+ + V+GA G+ WAG L +L D+T++ N+ + R YLGY VT
Sbjct: 196 AGIAGFFTEELVVMGAPGSFYWAGTIKVL--NLTDNTYLKLNDEVIMNRRYTYLGYAVTA 253
Query: 328 LP-SRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDV 386
S T + GAP+ + +G+V +F+ + G ++ G ++GSYFG LC VD+
Sbjct: 254 GHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDL 313
Query: 387 DQDGETELLLIGAPLFYGEQRGGRVFIYQRRQLG-FEEVSELQGDPGYPLGRFGEAITAL 445
+ DG ++LL +GAP+F + G+V +Y R G EE L GD Y FGE+I +L
Sbjct: 314 NGDGLSDLL-VGAPMFSEIRDEGQVTVYINRGNGALEEQLALTGDGAYN-AHFGESIASL 371
Query: 446 TDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIH 503
D++ DG DVA+GAP E+ GAVYI++G GG+ PQ S ++ G ++ ++ FG+SI
Sbjct: 372 DDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSIS 431
Query: 504 GVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKM 561
G D++G+G DV VGA +++L +RPV+ V + F P I + +C +
Sbjct: 432 GGIDMDGNGYPDVTVGAFMSDSVVLLRARPVI-TVDVSIFLPGSINITAPQC--HDGQQP 488
Query: 562 KEGVNITICFQIKSLIPQFQGRLV---ANLTYTLQLDGHRTRRRGLFP--------GGRH 610
+N+T CF F G+ V L Y L D + + +G P
Sbjct: 489 VNCLNVTTCF-------SFHGKHVPGEIGLNYVLMADVAK-KEKGQMPRVYFVLLGETMG 540
Query: 611 ELRRNIAVT-TSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAGKDIPPI 669
++ + +T +C + H VQD+ISPI +SL E T ++R + P+
Sbjct: 541 QVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSL-SEHVTGEEERELPPLTPV 599
Query: 670 LR---PSLHSETWEIPFEKN-----CGEDKKCEANLRVSFSPARSRALRLTAFASLSVEL 721
LR ++ + FE+N C D + + L +S ++ L L A ++S+ +
Sbjct: 600 LRWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNI 659
Query: 722 SLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSS 781
S+SNL +DAY + + L F + M + ++ +SCE L S L C+V
Sbjct: 660 SISNLGDDAYDANVSFNVSRELFF--INMWQ-KEEMGISCELLE------SDFLKCSVGF 710
Query: 782 PIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC---NNEDSDLLEDNSATTIIPILYP 838
P ++ ++F+T S G+ L VT N E S+ L DN+ ++P+++
Sbjct: 711 PFMRSKSKYEFSVIFDTSHLS--GEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHE 768
Query: 839 INILIQDQEDSTLYV 853
++ I T +V
Sbjct: 769 VDTSITGIMSPTSFV 783
Score = 36.6 bits (83), Expect = 0.13
Identities = 15/37 (40%), Positives = 28/37 (75%)
Query: 1007 YLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEA 1043
++ +S + G+L+ LL+ ++L+K+GFF+R KE +EA
Sbjct: 981 WIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEA 1017
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 198 bits (504), Expect = 2e-50
Identities = 228/874 (26%), Positives = 392/874 (44%), Gaps = 100/874 (11%)
Query: 239 DLFTELQKKIYVIEGTSKQDLTSF---NMELSSSGISADLSRGHAVVGAVGAKDWAGGFL 295
DL TEL K+I QD N +GIS+ ++ V+GA G+ W G
Sbjct: 171 DLRTELSKRI----APCYQDYVKKFGENFASCQAGISSFYTKDLIVMGAPGSSYWTGSLF 226
Query: 296 DLKADLQD-DTFIGNEPLTPEVRAG-YLGYTVTWLPSR-QKTSLLASGAPRYQHMGRVLL 352
F+ + +V+ G YLGY+V R Q T+ + GAP+++ +G+ +
Sbjct: 227 VYNITTNKYKAFLDKQN---QVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYI 283
Query: 353 FQEPQGGGHWSQVQTIH---GTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGG 409
F + ++ +H G ++GSYFG +C VD++ DG ++LL +GAP+ + G
Sbjct: 284 FSIDE-----KELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLL-VGAPMQSTIREEG 337
Query: 410 RVFIYQRRQLGF---EEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE-- 464
RVF+Y G + L G Y RFGE+I L DI+ DG DVA+GAP E+
Sbjct: 338 RVFVYINSGSGAVMNAMETNLVGSDKYA-ARFGESIVNLGDIDNDGFEDVAIGAPQEDDL 396
Query: 465 QGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGA--ES 522
QGA+YI+NGR G+S SQRIEG Q+ + FG+SI G D + +G DVAVGA
Sbjct: 397 QGAIYIYNGRADGISSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSD 456
Query: 523 QMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQG 582
++L +RPVV + +S P + + +C + + +++T+CF K + G
Sbjct: 457 SAVLLRTRPVVIVDASLSH-PESVNRTKFDCVENGWPSVC--IDLTLCFSYKG--KEVPG 511
Query: 583 RLVANLTYTLQLDGHRTRR---RGLFP--GGRHELRRNIAVTT-SMSCTDFSFHFPVCVQ 636
+V L Y + LD +R R F G + +I V++ +C V+
Sbjct: 512 YIV--LFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVR 569
Query: 637 DLISPINVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWE--IPFEKNCGEDKKCE 694
D+++PI + + L + R + PIL+ + + I F + C + C
Sbjct: 570 DILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CS 628
Query: 695 ANLRVS-----FSPARSRA-LRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKV 748
A+L+VS P ++ L + + +L + +SL N +DAY L + P GL F K+
Sbjct: 629 ADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKI 688
Query: 749 EMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSV 808
L+ ++CE + + S ++ L C++ + + + + S + +
Sbjct: 689 LELEEKQ---INCE-VTDNSGVVQ--LDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDL 742
Query: 809 ELHANVTCNNEDS-DLLEDNSATTIIPILYPINILIQDQEDST--LYVSFTPKGPKIHQV 865
+ + TC NE+ D L+ + T IP+ Y + + + + T +Y S P+ V
Sbjct: 743 SITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETCMV 802
Query: 866 KHMYQVRIQPSIHDHNIPTLEAVVGVPQP--PSEGPITHQWSVQMEPPVPCHYED----- 918
+ M + + P + + VP P + + VQ CH+E+
Sbjct: 803 EKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTG-ECHFENYQRVC 861
Query: 919 -LERLPDAAEPCLPGALFRCPVVFRQEILVQV----IGTLELVGEIEASSMFSLC----- 968
LE+ A + F R ++ + L G++E+ S+
Sbjct: 862 ALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEG 921
Query: 969 --SSLSISFNSSKHFHLYGS--------------NASLAQVVMKVDVVYEKQMLYLYVL- 1011
S L + S+ F + + + ++A V+++ + +++ Y ++
Sbjct: 922 RPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVAHVLLE-GLHHQRPKRYFTIVI 980
Query: 1012 ---SGIGGLLLLLLIFIVLYKVGFFKRNLKEKME 1042
S + GL++LLLI V++K GFFKR K ++
Sbjct: 981 ISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQ 1014
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 176 bits (445), Expect = 1e-43
Identities = 159/558 (28%), Positives = 253/558 (45%), Gaps = 62/558 (11%)
Query: 270 GISADLSRGHAVVGAVGAKDWAGGFLDLKA---DLQDDTFIGNEPLTPEVRAG-YLGYT- 324
G S ++ GA GA +W G ++ DL + ++ PE + Y+GYT
Sbjct: 200 GTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSY-----KDPEDQGNLYIGYTM 254
Query: 325 -VTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCG 383
V K + +GAPR++HMG V L + + GG + Q + G+Q+G+YFG +
Sbjct: 255 QVGSFILHPKNITIVTGAPRHRHMGAVFLLSQ-EAGGDLRRRQVLEGSQVGAYFGSAIAL 313
Query: 384 VDVDQDGETELLLIGAPLFYG--EQRGGRVFIYQRRQLGFEEVSE----LQGDPGYPLGR 437
D++ DG +LL +GAP ++ E+ GG ++++ Q G + L G G
Sbjct: 314 ADLNNDGWQDLL-VGAPYYFERKEEVGGAIYVFMN-QAGTSFPAHPSLLLHGPSG---SA 368
Query: 438 FGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQV-LSGIQ 496
FG ++ ++ DIN DG D+AVGAP E G VYI++ GL QP Q I G ++ L G+
Sbjct: 369 FGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLA 428
Query: 497 WFGRSIHGVKDLEGDGLADVAVGAESQMIV-LSSRPVVDMVTLMSFSPAEIPVHEVECSY 555
FG S+ G D++ + D+ VG+ S IV L +RPV+++V + P + C+
Sbjct: 429 TFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVH-KTLVPRPAVLDPALCTA 487
Query: 556 STSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRN 615
++ V + +CF R L YTL+ D R R F G +
Sbjct: 488 TSC------VQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFHG 541
Query: 616 IAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSL-WEEEGTPRDQRAGKDIPPILRPSL 674
M C ++D + PI +S+N+SL PR D PIL +
Sbjct: 542 FFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQ 601
Query: 675 HSET-WEIPFEKNCGEDKKCEANL--RVSFSPARSRALRLTAFA----SLSVELSLSNLE 727
E E+ F+K CG D KCE+NL R +F + + L ++ L + ++++N
Sbjct: 602 ALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTR 661
Query: 728 ------EDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSS 781
EDA+ L L PP L V + P +C+ + + C + +
Sbjct: 662 TSERSGEDAHEALLTLVVPPALLLSSV-------RPPGACQ--------ANETIFCELGN 706
Query: 782 PIFKAGHSVALQMMFNTL 799
P FK + L + F +
Sbjct: 707 P-FKRNQRMELLIAFEVI 723
Score = 32.3 bits (72), Expect = 2.5
Identities = 16/30 (53%), Positives = 23/30 (76%)
Query: 1006 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1035
L+L +++ GLLLL LI ++L+K GFFKR
Sbjct: 992 LWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 176 bits (445), Expect = 1e-43
Identities = 159/558 (28%), Positives = 253/558 (45%), Gaps = 62/558 (11%)
Query: 270 GISADLSRGHAVVGAVGAKDWAGGFLDLKA---DLQDDTFIGNEPLTPEVRAG-YLGYT- 324
G S ++ GA GA +W G ++ DL + ++ PE + Y+GYT
Sbjct: 200 GTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSY-----KDPEDQGNLYIGYTM 254
Query: 325 -VTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCG 383
V K + +GAPR++HMG V L + + GG + Q + G+Q+G+YFG +
Sbjct: 255 QVGSFILHPKNITIVTGAPRHRHMGAVFLLSQ-EAGGDLRRRQVLEGSQVGAYFGSAIAL 313
Query: 384 VDVDQDGETELLLIGAPLFYG--EQRGGRVFIYQRRQLGFEEVSE----LQGDPGYPLGR 437
D++ DG +LL +GAP ++ E+ GG ++++ Q G + L G G
Sbjct: 314 ADLNNDGWQDLL-VGAPYYFERKEEVGGAIYVFMN-QAGTSFPAHPSLLLHGPSG---SA 368
Query: 438 FGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQV-LSGIQ 496
FG ++ ++ DIN DG D+AVGAP E G VYI++ GL QP Q I G ++ L G+
Sbjct: 369 FGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLA 428
Query: 497 WFGRSIHGVKDLEGDGLADVAVGAESQMIV-LSSRPVVDMVTLMSFSPAEIPVHEVECSY 555
FG S+ G D++ + D+ VG+ S IV L +RPV+++V + P + C+
Sbjct: 429 TFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVH-KTLVPRPAVLDPALCTA 487
Query: 556 STSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRN 615
++ V + +CF R L YTL+ D R R F G +
Sbjct: 488 TSC------VQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFHG 541
Query: 616 IAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSL-WEEEGTPRDQRAGKDIPPILRPSL 674
M C ++D + PI +S+N+SL PR D PIL +
Sbjct: 542 FFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQ 601
Query: 675 HSET-WEIPFEKNCGEDKKCEANL--RVSFSPARSRALRLTAFA----SLSVELSLSNLE 727
E E+ F+K CG D KCE+NL R +F + + L ++ L + ++++N
Sbjct: 602 ALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTR 661
Query: 728 ------EDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSS 781
EDA+ L L PP L V + P +C+ + + C + +
Sbjct: 662 TSERSGEDAHEALLTLVVPPALLLSSV-------RPPGACQ--------ANETIFCELGN 706
Query: 782 PIFKAGHSVALQMMFNTL 799
P FK + L + F +
Sbjct: 707 P-FKRNQRMELLIAFEVI 723
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 160 bits (404), Expect = 8e-39
Identities = 229/914 (25%), Positives = 375/914 (41%), Gaps = 168/914 (18%)
Query: 279 HAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRA----------GYLGYTVT-- 326
+ + GA G +W G D D + + L P R YLG+++
Sbjct: 211 YLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSG 270
Query: 327 -WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVD 385
L ++ S +A GAPR H G V++ ++ +V + G ++ S FG L D
Sbjct: 271 KGLVRAEELSFVA-GAPRANHKGAVVILRKDSASRLVPEVM-LSGERLTSGFGYSLAVAD 328
Query: 386 VDQDGETELLLIGAPLFYGEQR--GGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAIT 443
++ DG +L+ +GAP F+ Q GG V++Y + + +S L+ G P FG ++
Sbjct: 329 LNSDGWPDLI-VGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC-GSPDSMFGISLA 386
Query: 444 ALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIH 503
L D+N DG D+AVGAP + G V+I++G G+ +PSQ +EG V GI+ FG S+
Sbjct: 387 VLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSFGYSLS 444
Query: 504 GVKDLEGDGLADVAVGAESQMIVL-SSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMK 562
G D++G+ D+ VG+ + VL +RP++ + +S +P I + + C+ S
Sbjct: 445 GSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHS---- 500
Query: 563 EGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSM 622
V++ +CF + +P VA L Y L D R R RG P L RN+
Sbjct: 501 VCVDLRVCFSYIA-VPSSYSPTVA-LDYVLDADTDR-RLRGQVPRVTF-LSRNLEEPKHQ 556
Query: 623 S-------------CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRA--GKDIP 667
+ C D F V+D + I V+L++SL TPR +R G+ +P
Sbjct: 557 ASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ----TPRLRRQAPGQGLP 612
Query: 668 PILRPSLHS-----ETWEIPFEKN-CGEDKKCEANLRV------------SFSPARSRAL 709
P+ P L++ + EI F K CGEDK C++NL++ F P
Sbjct: 613 PVA-PILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVD 671
Query: 710 RLTAFASLS------VELSLSNLE----------EDAYWVQLDLHFPPGLSFRKVEML-- 751
TA +LS +EL ++NL +DA+ QL + P L + V L
Sbjct: 672 GTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDP 731
Query: 752 -----------------------KPHSQIP---------VSCEELPEESRLLSRALSCN- 778
K +Q+ +S E E LL +S
Sbjct: 732 AEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQE 791
Query: 779 -----------VSSPIFKAGHSVALQMMFNTLVNSSWGDSVE------LHANVTCNNEDS 821
+ P+ AG ++ Q+ F+ +V E + VT +N+
Sbjct: 792 LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQ 851
Query: 822 DLLEDNSATTIIP----------ILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQV 871
L SA I +LYP+ + ++ + +P+ +H
Sbjct: 852 SLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILH-------- 903
Query: 872 RIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLP 931
+ D LE P + P Q PV + D A
Sbjct: 904 -LDVDSRDRRRRELEP------PEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTAN 956
Query: 932 GALFRCPVV-FRQEILVQVIGTL---ELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSN 987
+F CP+ F + ++ V G L + E A + +I+ SS +
Sbjct: 957 CVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDA 1016
Query: 988 ASLAQVVMKVD---VVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAG 1044
+++ V++ +D VV E ++ +L+ + GLL+L L+ ++L+K+GFFKR +
Sbjct: 1017 STVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVP 1076
Query: 1045 RGVPNGIPAEDSEQ 1058
+ IP ED +Q
Sbjct: 1077 QYHAVKIPREDRQQ 1090
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 157 bits (397), Expect = 5e-38
Identities = 233/919 (25%), Positives = 378/919 (41%), Gaps = 174/919 (18%)
Query: 279 HAVVGAVGAKDWAG---------GFLDLKADLQDDTF-IGNEP-----LTPEVRAGYLGY 323
+ + GA G +W G G DL A L D + G E L P Y G+
Sbjct: 114 YLLFGAPGTYNWKGTARVELCAQGSADL-AHLDDGPYEAGGEKEQDPRLIPVPANSYFGF 172
Query: 324 TVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGE 380
++ L ++ S +A GAPR H G V++ ++ +V + G ++ S FG
Sbjct: 173 SIDSGKGLVRAEELSFVA-GAPRANHKGAVVILRKDSASRLVPEVM-LSGERLTSGFGYS 230
Query: 381 LCGVDVDQDGETELLLIGAPLFYGEQR--GGRVFIYQRRQLGFEEVSELQGDPGYPLGRF 438
L D++ DG +L+ +GAP F+ Q GG V++Y + + +S L+ G P F
Sbjct: 231 LAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC-GSPDSMF 288
Query: 439 GEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWF 498
G ++ L D+N DG D+AVGAP + G V+I++G G+ +PSQ +EG V GI+ F
Sbjct: 289 GISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSF 346
Query: 499 GRSIHGVKDLEGDGLADVAVGAESQMIVL-SSRPVVDMVTLMSFSPAEIPVHEVECSYST 557
G S+ G D++G+ D+ VG+ + VL +RP++ + +S +P I + + C+
Sbjct: 347 GYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGH 406
Query: 558 SNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIA 617
S V++ +CF + +P VA L Y L D R R RG P L RN+
Sbjct: 407 S----VCVDLRVCFSYIA-VPSSYSPTVA-LDYVLDADTDR-RLRGQVPRVTF-LSRNLE 458
Query: 618 VTTSMS-------------CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRA-- 662
+ C D F V+D + I V+L++SL TPR +R
Sbjct: 459 EPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ----TPRLRRQAP 514
Query: 663 GKDIPPILRPSLHS-----ETWEIPFEKN-CGEDKKCEANLRV------------SFSPA 704
G+ +PP+ P L++ + EI F K CGEDK C++NL++ F P
Sbjct: 515 GQGLPPVA-PILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPL 573
Query: 705 RSRALRLTAFASLS------VELSLSNLE----------EDAYWVQLDLHFPPGLSFRKV 748
TA +LS +EL ++NL +DA+ QL + P L + V
Sbjct: 574 PMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGV 633
Query: 749 EML-------------------------KPHSQIP---------VSCEELPEESRLLSRA 774
L K +Q+ +S E E LL
Sbjct: 634 RALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLAT 693
Query: 775 LSCN------------VSSPIFKAGHSVALQMMFNTLVNSSWGDSVE------LHANVTC 816
+S + P+ AG ++ Q+ F+ +V E + VT
Sbjct: 694 ISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTV 753
Query: 817 NNEDSDLLEDNSATTIIP----------ILYPINILIQDQEDSTLYVSFTPKGPKIHQVK 866
+N+ L SA I +LYP+ + ++ + +P+ +H
Sbjct: 754 SNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILH--- 810
Query: 867 HMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAA 926
+ D LE P + P Q PV + D A
Sbjct: 811 ------LDVDSRDRRRRELEP------PEQQEPGERQEPSMSWWPVSSAEKKKNITLDCA 858
Query: 927 EPCLPGALFRCPVV-FRQEILVQVIGTL---ELVGEIEASSMFSLCSSLSISFNSSKHFH 982
+F CP+ F + ++ V G L + E A + +I+ SS
Sbjct: 859 RGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNL 918
Query: 983 LYGSNASLAQVVMKVD---VVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKE 1039
+ +++ V++ +D VV E ++ +L+ + GLL+L L+ ++L+K+GFFKR
Sbjct: 919 MLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHP 978
Query: 1040 KMEAGRGVPNGIPAEDSEQ 1058
+ + IP ED +Q
Sbjct: 979 EATVPQYHAVKIPREDRQQ 997
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 157 bits (397), Expect = 5e-38
Identities = 233/919 (25%), Positives = 378/919 (41%), Gaps = 174/919 (18%)
Query: 279 HAVVGAVGAKDWAG---------GFLDLKADLQDDTF-IGNEP-----LTPEVRAGYLGY 323
+ + GA G +W G G DL A L D + G E L P Y G+
Sbjct: 211 YLLFGAPGTYNWKGTARVELCAQGSADL-AHLDDGPYEAGGEKEQDPRLIPVPANSYFGF 269
Query: 324 TVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGE 380
++ L ++ S +A GAPR H G V++ ++ +V + G ++ S FG
Sbjct: 270 SIDSGKGLVRAEELSFVA-GAPRANHKGAVVILRKDSASRLVPEVM-LSGERLTSGFGYS 327
Query: 381 LCGVDVDQDGETELLLIGAPLFYGEQR--GGRVFIYQRRQLGFEEVSELQGDPGYPLGRF 438
L D++ DG +L+ +GAP F+ Q GG V++Y + + +S L+ G P F
Sbjct: 328 LAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC-GSPDSMF 385
Query: 439 GEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWF 498
G ++ L D+N DG D+AVGAP + G V+I++G G+ +PSQ +EG V GI+ F
Sbjct: 386 GISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSF 443
Query: 499 GRSIHGVKDLEGDGLADVAVGAESQMIVL-SSRPVVDMVTLMSFSPAEIPVHEVECSYST 557
G S+ G D++G+ D+ VG+ + VL +RP++ + +S +P I + + C+
Sbjct: 444 GYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGH 503
Query: 558 SNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIA 617
S V++ +CF + +P VA L Y L D R R RG P L RN+
Sbjct: 504 S----VCVDLRVCFSYIA-VPSSYSPTVA-LDYVLDADTDR-RLRGQVPRVTF-LSRNLE 555
Query: 618 VTTSMS-------------CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRA-- 662
+ C D F V+D + I V+L++SL TPR +R
Sbjct: 556 EPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ----TPRLRRQAP 611
Query: 663 GKDIPPILRPSLHS-----ETWEIPFEKN-CGEDKKCEANLRV------------SFSPA 704
G+ +PP+ P L++ + EI F K CGEDK C++NL++ F P
Sbjct: 612 GQGLPPVA-PILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPL 670
Query: 705 RSRALRLTAFASLS------VELSLSNLE----------EDAYWVQLDLHFPPGLSFRKV 748
TA +LS +EL ++NL +DA+ QL + P L + V
Sbjct: 671 PMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGV 730
Query: 749 EML-------------------------KPHSQIP---------VSCEELPEESRLLSRA 774
L K +Q+ +S E E LL
Sbjct: 731 RALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLAT 790
Query: 775 LSCN------------VSSPIFKAGHSVALQMMFNTLVNSSWGDSVE------LHANVTC 816
+S + P+ AG ++ Q+ F+ +V E + VT
Sbjct: 791 ISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTV 850
Query: 817 NNEDSDLLEDNSATTIIP----------ILYPINILIQDQEDSTLYVSFTPKGPKIHQVK 866
+N+ L SA I +LYP+ + ++ + +P+ +H
Sbjct: 851 SNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILH--- 907
Query: 867 HMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAA 926
+ D LE P + P Q PV + D A
Sbjct: 908 ------LDVDSRDRRRRELEP------PEQQEPGERQEPSMSWWPVSSAEKKKNITLDCA 955
Query: 927 EPCLPGALFRCPVV-FRQEILVQVIGTL---ELVGEIEASSMFSLCSSLSISFNSSKHFH 982
+F CP+ F + ++ V G L + E A + +I+ SS
Sbjct: 956 RGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNL 1015
Query: 983 LYGSNASLAQVVMKVD---VVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKE 1039
+ +++ V++ +D VV E ++ +L+ + GLL+L L+ ++L+K+GFFKR
Sbjct: 1016 MLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHP 1075
Query: 1040 KMEAGRGVPNGIPAEDSEQ 1058
+ + IP ED +Q
Sbjct: 1076 EATVPQYHAVKIPREDRQQ 1094
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 153 bits (386), Expect = 1e-36
Identities = 209/855 (24%), Positives = 357/855 (41%), Gaps = 119/855 (13%)
Query: 270 GISADLSR-GHAVVGAVGAKDWAGGFLDLKADLQDDTF--------IGNEPLTPEVRA-- 318
G SA+ ++ G V+G G+ W G L + +++ + + T + +
Sbjct: 208 GFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPEYLINLVQGQLQTRQASSIY 267
Query: 319 --GYLGYTVTWLP-SRQKTSLLASGAPRYQ-HMGRVLLFQEPQGGGHWSQVQTIHGTQIG 374
YLGY+V S T +G P+ G V + G + G Q+
Sbjct: 268 DDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTILN----GSDIRSLYNFSGEQMA 323
Query: 375 SYFGGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQRRQLGFEEVSELQ 428
SYFG + DV+ DG +LL +GAPL Q GRV++Y + G E L
Sbjct: 324 SYFGYAVAATDVNGDGLDDLL-VGAPLLMDRTPDGRPQEVGRVYVYLQHPAGIEPTPTLT 382
Query: 429 GDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHGGLSPQPSQR 485
GRFG ++T L D++ DG DVA+GAP +QG V++F G GGL +PSQ
Sbjct: 383 LTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGGLGSKPSQV 442
Query: 486 IEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTLMSFS 542
++ S +FG ++ G +DL+G+G D+ VG+ + +V RP+V ++
Sbjct: 443 LQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIVSASASLTIF 502
Query: 543 PAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVAN---LTYTLQLDGHRT 599
PA E C S +N++ C G+ VA+ T LQLD +
Sbjct: 503 PAMFNPEERSC--SLEGNPVACINLSFCLNA-------SGKHVADSIGFTVELQLDWQKQ 553
Query: 600 R---RRGLFPGGRH-ELRRNIAVTTSM--SCTDFSFHF--PVCVQDLISPINVSLNFSLW 651
+ RR LF R L + + + C + + +D +SPI+++LNFSL
Sbjct: 554 KGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSL- 612
Query: 652 EEEGTPRDQRAGKDIPPILRPSLHSETWEIPFEK-----NCGEDKKCEANLRVSFSPARS 706
+ P D LRP+LH ++ +K +CGED C +L++ ++
Sbjct: 613 -DPQAPVDSHG-------LRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEVFGEQN 664
Query: 707 RALRLTAFASLSVELSLSNL-EEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELP 765
+ L +L++ N+ E AY +L + PP + + + P + +SC+
Sbjct: 665 H-VYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGL-VRHPGNFSSLSCDYFA 722
Query: 766 EESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANV---TCNNEDSD 822
SR L C++ +P+ KAG S+ + F +++ + NN SD
Sbjct: 723 VNQ---SRLLVCDLGNPM-KAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSD 778
Query: 823 L------LEDNSATTIIPILYPINIL--IQDQEDSTLYVSFTPKGPKIHQV--------- 865
+ +E + T+ + P +L + D GP +H V
Sbjct: 779 VVSFRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPS 838
Query: 866 ---KHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERL 922
+ + ++ ++ + + V G+ + PI + ++++P H++
Sbjct: 839 SISQGVLELSCPQALEGQQLLYVTRVTGL-NCTTNHPINPK-GLELDPEGSLHHQQKREA 896
Query: 923 PDAAEPCLPGALFRCPVV--FRQE-----ILVQVIGTLELVGEIEASSM-------FSL- 967
P + + +CP FR + Q +L+L + A + FSL
Sbjct: 897 PSRSSASSGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQPFSLQ 956
Query: 968 CSSLSISFNSSKHF---HLYGSNASLAQVVM--KVDVVYEKQMLYLYVLSGIGGLLLLLL 1022
C ++ + L +A V K + Y L++ +L+ + GLLLL L
Sbjct: 957 CEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVP-LWIIILAILFGLLLLGL 1015
Query: 1023 IFIVLYKVGFFKRNL 1037
+ +LYK+GFFKR+L
Sbjct: 1016 LIYILYKLGFFKRSL 1030
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor
[Homo sapiens]
Length = 1091
Score = 142 bits (357), Expect = 2e-33
Identities = 155/646 (23%), Positives = 279/646 (43%), Gaps = 111/646 (17%)
Query: 270 GISADLSRG--HAVVGAVGAKDWAGGFLDLKADLQDDTFIG-----------------NE 310
G++A ++ + V GA G +W G ++ + +++TF +E
Sbjct: 191 GVAATFTKDFHYIVFGAPGTYNWKG---IVRVEQKNNTFFDMNIFEDGPYEVGGETEHDE 247
Query: 311 PLTPEVRAGYLGYTVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQT 367
L P YLG+++ + S+ + + + SGAPR H G V+L + H
Sbjct: 248 SLVPVPANSYLGFSLDSGKGIVSKDEITFV-SGAPRANHSGAVVLLKRDMKSAHLLPEHI 306
Query: 368 IHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE--QRGGRVFIYQRRQLGFEEVS 425
G + S FG ++ VD+++DG +++ IGAP ++ + GG V++Y +Q + V
Sbjct: 307 FDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGRWNNVK 365
Query: 426 ELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQR 485
++ + G FG A+ + DIN DG D+AVGAP ++ G V+I++G G++ +P
Sbjct: 366 PIRLN-GTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKP--- 421
Query: 486 IEGTQVLSGIQ-WFGRSIHGVKDLEGDGLADVAVGAESQMI-VLSSRPVVDMVTLMSFSP 543
TQVL GI +FG SI G DL+ + DVAVG+ S + + SRPV+++ ++ +P
Sbjct: 422 ---TQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTP 478
Query: 544 AEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVAN----LTYTLQLDGHRT 599
I + + K G IC Q+KS N + TL+ + R
Sbjct: 479 NRIDLRQ---------KTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERR 529
Query: 600 ----------RRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFS 649
R +G P EL + C + + ++D + PI ++ +
Sbjct: 530 KSGLSSRVQFRNQGSEPKYTQEL--TLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVE 587
Query: 650 LWEEEGTPRDQRAGKDIPPILRPSLHSETWEIP------FEKNCGEDKKCEANLRVSF-- 701
+ E P +R +P +L P L+S+ + ++ CG+D C +NL++ +
Sbjct: 588 IQE----PSSRRRVNSLPEVL-PILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKF 642
Query: 702 ------------------------SPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDL 737
+ AL +T S S + + +DA+ +L
Sbjct: 643 CTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIA 702
Query: 738 HFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFN 797
FP L++ L+ + +SC S+ C + +P FK +V ++ +
Sbjct: 703 TFPDTLTYSAYRELRAFPEKQLSCVANQNGSQ-----ADCELGNP-FKRNSNVTFYLVLS 756
Query: 798 TLVNSSWGDSVELHANV---TCNNEDSDLLEDNSATTIIPILYPIN 840
T D+ +L N+ T +N+D+ A +I +L ++
Sbjct: 757 T--TEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVS 800
Score = 30.8 bits (68), Expect = 7.3
Identities = 11/30 (36%), Positives = 23/30 (76%)
Query: 1007 YLYVLSGIGGLLLLLLIFIVLYKVGFFKRN 1036
++ +++ + G+L+L L+ +L+K GFFKR+
Sbjct: 1016 WIILVAILAGILMLALLVFILWKCGFFKRS 1045
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor
[Homo sapiens]
Length = 1073
Score = 142 bits (357), Expect = 2e-33
Identities = 155/646 (23%), Positives = 279/646 (43%), Gaps = 111/646 (17%)
Query: 270 GISADLSRG--HAVVGAVGAKDWAGGFLDLKADLQDDTFIG-----------------NE 310
G++A ++ + V GA G +W G ++ + +++TF +E
Sbjct: 191 GVAATFTKDFHYIVFGAPGTYNWKG---IVRVEQKNNTFFDMNIFEDGPYEVGGETEHDE 247
Query: 311 PLTPEVRAGYLGYTVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQT 367
L P YLG+++ + S+ + + + SGAPR H G V+L + H
Sbjct: 248 SLVPVPANSYLGFSLDSGKGIVSKDEITFV-SGAPRANHSGAVVLLKRDMKSAHLLPEHI 306
Query: 368 IHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE--QRGGRVFIYQRRQLGFEEVS 425
G + S FG ++ VD+++DG +++ IGAP ++ + GG V++Y +Q + V
Sbjct: 307 FDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGRWNNVK 365
Query: 426 ELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQR 485
++ + G FG A+ + DIN DG D+AVGAP ++ G V+I++G G++ +P
Sbjct: 366 PIRLN-GTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKP--- 421
Query: 486 IEGTQVLSGIQ-WFGRSIHGVKDLEGDGLADVAVGAESQMI-VLSSRPVVDMVTLMSFSP 543
TQVL GI +FG SI G DL+ + DVAVG+ S + + SRPV+++ ++ +P
Sbjct: 422 ---TQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTP 478
Query: 544 AEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVAN----LTYTLQLDGHRT 599
I + + K G IC Q+KS N + TL+ + R
Sbjct: 479 NRIDLRQ---------KTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERR 529
Query: 600 ----------RRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFS 649
R +G P EL + C + + ++D + PI ++ +
Sbjct: 530 KSGLSSRVQFRNQGSEPKYTQEL--TLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVE 587
Query: 650 LWEEEGTPRDQRAGKDIPPILRPSLHSETWEIP------FEKNCGEDKKCEANLRVSF-- 701
+ E P +R +P +L P L+S+ + ++ CG+D C +NL++ +
Sbjct: 588 IQE----PSSRRRVNSLPEVL-PILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKF 642
Query: 702 ------------------------SPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDL 737
+ AL +T S S + + +DA+ +L
Sbjct: 643 CTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIA 702
Query: 738 HFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFN 797
FP L++ L+ + +SC S+ C + +P FK +V ++ +
Sbjct: 703 TFPDTLTYSAYRELRAFPEKQLSCVANQNGSQ-----ADCELGNP-FKRNSNVTFYLVLS 756
Query: 798 TLVNSSWGDSVELHANV---TCNNEDSDLLEDNSATTIIPILYPIN 840
T D+ +L N+ T +N+D+ A +I +L ++
Sbjct: 757 T--TEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVS 800
Score = 36.2 bits (82), Expect = 0.17
Identities = 14/37 (37%), Positives = 27/37 (72%)
Query: 1007 YLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEA 1043
++ +++ + G+L+L L+ +L+K GFFKRN K+ +A
Sbjct: 1016 WIILVAILAGILMLALLVFILWKCGFFKRNKKDHYDA 1052
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 141 bits (356), Expect = 3e-33
Identities = 158/598 (26%), Positives = 271/598 (45%), Gaps = 75/598 (12%)
Query: 269 SGISADLSR-GHAVVGAVGAKDWAG--------------GFLDLKADLQDDTFIGNEPLT 313
+G S D + G +VG G+ W G F D+ L + P +
Sbjct: 202 AGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPAS 261
Query: 314 PEVRAGYLGYTVTWLP-SRQKTSLLASGAPR-YQHMGRVLLFQEPQGGGHWSQVQTIHGT 371
+ YLGY+V + L +G PR Q+ G V + + +Q G
Sbjct: 262 YD--DSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTD----MTFIQNFTGE 315
Query: 372 QIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQ------RGGRVFIY-QRRQLGFEEV 424
Q+ SYFG + DV+ DG ++L +GAPLF + G++++Y Q L F +
Sbjct: 316 QMASYFGYTVVVSDVNSDGLDDVL-VGAPLFMEREFESNPREVGQIYLYLQVSSLLFRDP 374
Query: 425 SELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHGGLSPQ 481
L G + GRFG A+ L D+N DG D+A+G P +++G V I+NG GL+ +
Sbjct: 375 QILTGTETF--GRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTK 432
Query: 482 PSQRIEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTL 538
PSQ ++G + FG ++ G D++ + D+ VGA ++ V +RPVV +
Sbjct: 433 PSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQ 492
Query: 539 MSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVAN---LTYTLQLD 595
+ P I + C ++ + + CF ++ + G+ +AN L +QLD
Sbjct: 493 LLLHPMIINLENKTC------QVPDSMTSAACFSLR-VCASVTGQSIANTIVLMAEVQLD 545
Query: 596 GHRTR---RRGLFPGGRHELRRNIAVT----TSMSCTDFSFHF--PVCVQDLISPINVSL 646
+ + +R LF H+ R + S C DF + +D +SPIN+SL
Sbjct: 546 SLKQKGAIKRTLFL-DNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISL 604
Query: 647 NFSLWEEEGTPRDQRAGKDIPPIL---RPSLHSETWEIPFEKNCGEDKKCEANLRVSFSP 703
N+SL +E T ++ G ++ PIL R ++ SE I + CGED C +L++S P
Sbjct: 605 NYSL--DESTFKE---GLEVKPILNYYRENIVSEQAHILVD--CGEDNLCVPDLKLSARP 657
Query: 704 ARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEE 763
+ + + + L + ++ N E AY +L + P + +E + P+SCE
Sbjct: 658 DKHQVI-IGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFR-PLSCEY 715
Query: 764 LPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDS 821
E ++R + C++ +P+ +G + +L + F S+ + +N+D+
Sbjct: 716 KMEN---VTRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDN 769
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 140 bits (353), Expect = 7e-33
Identities = 207/827 (25%), Positives = 340/827 (41%), Gaps = 143/827 (17%)
Query: 314 PEVRAGYLGYTVTW--LPSRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGHWSQVQTIHG 370
PE GY GY+V T+ GAP + +G V + ++ ++ + G
Sbjct: 259 PEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDS-----YYQRLHRLRG 313
Query: 371 TQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRG-------GRVFIYQRRQ----L 419
Q+ SYFG + DV+ DG +LL +GAPL Y E R GRV+++ + + L
Sbjct: 314 EQMASYFGHSVAVTDVNGDGRHDLL-VGAPL-YMESRADRKLAEVGRVYLFLQPRGPHAL 371
Query: 420 GFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHG 476
G + L G Y GRFG AI L D++ DG D+AV AP +G V +F G+
Sbjct: 372 GAPSLL-LTGTQLY--GRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSE 428
Query: 477 GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVD 534
GL +PSQ ++ FG S+ G D++ +G D+ VGA +Q+ V ++PVV
Sbjct: 429 GLRSRPSQVLDSPFPTGSA--FGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVK 486
Query: 535 MVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKS-LIPQFQGRLVANLTYTLQ 593
+ + P + C + NI +C IPQ +L LQ
Sbjct: 487 ASVQLLVQDSLNPAVK-SCVLPQTKTPVSCFNIQMCVGATGHNIPQ-----KLSLNAELQ 540
Query: 594 LDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVC------------VQDLISP 641
LD + R+ G R L + T+++ H P+C +D +SP
Sbjct: 541 LDRQKPRQ-----GRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSP 595
Query: 642 INVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSF 701
I +SLN SL E AG +L H + + +CGED C L+++
Sbjct: 596 IVLSLNVSLPPTE-------AGMAPAVVLHGDTHVQE-QTRIVLDCGEDDVCVPQLQLTA 647
Query: 702 SPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSC 761
S S L + A L +++ +N E AY +L +H P G + + + + C
Sbjct: 648 SVTGS-PLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRA-LSNVEGFERLIC 705
Query: 762 EELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDS 821
+ E +R + C + +P+ K + + M+ + G+SV + N +
Sbjct: 706 NQKKENE---TRVVLCELGNPM-KKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQN 761
Query: 822 DLLEDNSATTIIPI-------------LYPINILIQDQEDSTLYVSFTPKGPKIHQVKHM 868
NS ++ + +P ++++ +E S GPK V+H
Sbjct: 762 ----PNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPK---VEHT 814
Query: 869 YQV-------------------RIQPS--IHDHNIPTLEAVVGVPQPPSEGPITHQWSVQ 907
Y++ + QPS ++ +I + PQPP P+ W +
Sbjct: 815 YELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPP-VNPLKVDWGLP 873
Query: 908 MEPPVPCHYEDLER------LPDAAEP------------CLPGALFRC---PVVFRQEIL 946
+ P P H +R LP+ +P P + +C + Q +
Sbjct: 874 IPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAM 933
Query: 947 VQVIGTLELVGEIEAS-SMFSLCSSLSISFNSSKH----FHLYGSNASLAQVVMKVDVVY 1001
V V+ L L + F L S + +S + L A + +++ +
Sbjct: 934 VTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLR--ALE 991
Query: 1002 EKQMLYLYVLSGI-GGLLLLLLIFIVLYKVGFFKRN---LKEKMEAG 1044
E+ + +VL G+ GGLLLL ++ + ++KVGFFKRN L+E E G
Sbjct: 992 ERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEG 1038
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 123 bits (308), Expect = 1e-27
Identities = 152/602 (25%), Positives = 254/602 (42%), Gaps = 65/602 (10%)
Query: 257 QDLTSFNMELSSSGISADLSRGHAVV-GAVGAKDWAGGFL-----DLKADLQDDTF---I 307
QD+ + G S D ++ V+ G G+ W G + ++ + + +
Sbjct: 129 QDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKY 188
Query: 308 GNEPLTPEVRA----GYLGYTVTWLP-SRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGH 361
N+ T +A YLGY+V + SG PR +G V ++ G +
Sbjct: 189 NNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYD----GKN 244
Query: 362 WSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQ 415
S + G Q+ +YFG + D++ D ++ IGAPLF Q G+V +
Sbjct: 245 MSSLYNFTGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL 303
Query: 416 RRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFN 472
+R G + ++L G + RFG AI L D++ DG D+A+ AP +++G VYIFN
Sbjct: 304 QRASGDFQTTKLNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFN 361
Query: 473 GRHGGLSPQPSQRIEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSS 529
GR GL+ PSQ +EG + FG S+ G D++ +G D+ VGA + I+ +
Sbjct: 362 GRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRA 421
Query: 530 RPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI--KSLIPQFQGRLVAN 587
RPV+ + + P+ + CS + N+ C + K ++P+ V
Sbjct: 422 RPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL 481
Query: 588 LTYTLQLDGHRTRRRGLFPGGR---HELRRNIAVTTSMSCTDFSFHF--PVCVQDLISPI 642
L L+ G RR LF R H I+ M C + + +D ++PI
Sbjct: 482 LLDKLKQKG--AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPI 539
Query: 643 NVSLNFSLWEEEGTPRDQRAGKD---IPPILR---PSLHSETWEIPFEKNCGEDKKCEAN 696
+ + + L D R D + PIL P+ S I + CGED C+
Sbjct: 540 TIFMEYRL--------DYRTAADTTGLQPILNQFTPANISRQAHILLD--CGEDNVCKPK 589
Query: 697 LRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQ 756
L VS + + + + L++ + N E AY +L + P F V + +
Sbjct: 590 LEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGV-VRNNEAL 647
Query: 757 IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC 816
+SC E +R + C++ +P+ KAG + + F+ S SV+ +
Sbjct: 648 ARLSCAFKTENQ---TRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQS 703
Query: 817 NN 818
+N
Sbjct: 704 SN 705
Score = 34.3 bits (77), Expect = 0.66
Identities = 13/30 (43%), Positives = 24/30 (80%)
Query: 1006 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1035
+++ +L+ + GLLLL ++ V+Y++GFFKR
Sbjct: 948 VWVIILAVLAGLLLLAVLVFVMYRMGFFKR 977
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 123 bits (308), Expect = 1e-27
Identities = 152/602 (25%), Positives = 254/602 (42%), Gaps = 65/602 (10%)
Query: 257 QDLTSFNMELSSSGISADLSRGHAVV-GAVGAKDWAGGFL-----DLKADLQDDTF---I 307
QD+ + G S D ++ V+ G G+ W G + ++ + + +
Sbjct: 175 QDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKY 234
Query: 308 GNEPLTPEVRA----GYLGYTVTWLP-SRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGH 361
N+ T +A YLGY+V + SG PR +G V ++ G +
Sbjct: 235 NNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYD----GKN 290
Query: 362 WSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQ 415
S + G Q+ +YFG + D++ D ++ IGAPLF Q G+V +
Sbjct: 291 MSSLYNFTGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL 349
Query: 416 RRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFN 472
+R G + ++L G + RFG AI L D++ DG D+A+ AP +++G VYIFN
Sbjct: 350 QRASGDFQTTKLNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFN 407
Query: 473 GRHGGLSPQPSQRIEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSS 529
GR GL+ PSQ +EG + FG S+ G D++ +G D+ VGA + I+ +
Sbjct: 408 GRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRA 467
Query: 530 RPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI--KSLIPQFQGRLVAN 587
RPV+ + + P+ + CS + N+ C + K ++P+ V
Sbjct: 468 RPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL 527
Query: 588 LTYTLQLDGHRTRRRGLFPGGR---HELRRNIAVTTSMSCTDFSFHF--PVCVQDLISPI 642
L L+ G RR LF R H I+ M C + + +D ++PI
Sbjct: 528 LLDKLKQKG--AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPI 585
Query: 643 NVSLNFSLWEEEGTPRDQRAGKD---IPPILR---PSLHSETWEIPFEKNCGEDKKCEAN 696
+ + + L D R D + PIL P+ S I + CGED C+
Sbjct: 586 TIFMEYRL--------DYRTAADTTGLQPILNQFTPANISRQAHILLD--CGEDNVCKPK 635
Query: 697 LRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQ 756
L VS + + + + L++ + N E AY +L + P F V + +
Sbjct: 636 LEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGV-VRNNEAL 693
Query: 757 IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC 816
+SC E +R + C++ +P+ KAG + + F+ S SV+ +
Sbjct: 694 ARLSCAFKTENQ---TRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQS 749
Query: 817 NN 818
+N
Sbjct: 750 SN 751
Score = 34.3 bits (77), Expect = 0.66
Identities = 13/30 (43%), Positives = 24/30 (80%)
Query: 1006 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1035
+++ +L+ + GLLLL ++ V+Y++GFFKR
Sbjct: 994 VWVIILAVLAGLLLLAVLVFVMYRMGFFKR 1023
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 120 bits (302), Expect = 5e-27
Identities = 139/526 (26%), Positives = 227/526 (43%), Gaps = 52/526 (9%)
Query: 320 YLGYTVTWLP-SRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGHWSQVQTIHGTQIGSYF 377
YLGY+V + SG PR +G V ++ G + S + G Q+ +YF
Sbjct: 215 YLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYD----GKNMSSLYNFTGEQMAAYF 270
Query: 378 GGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQRRQLGFEEVSELQGDP 431
G + D++ D ++ IGAPLF Q G+V + +R G + ++L G
Sbjct: 271 GFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFE 329
Query: 432 GYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHGGLSPQPSQRIEG 488
+ RFG AI L D++ DG D+A+ AP +++G VYIFNGR GL+ PSQ +EG
Sbjct: 330 VF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEG 387
Query: 489 TQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTLMSFSPAE 545
+ FG S+ G D++ +G D+ VGA + I+ +RPV+ + + P+
Sbjct: 388 QWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSI 447
Query: 546 IPVHEVECSYSTSNKMKEGVNITICFQI--KSLIPQFQGRLVANLTYTLQLDGHRTRRRG 603
+ CS + N+ C + K ++P+ V L L+ G RR
Sbjct: 448 LNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG--AIRRA 505
Query: 604 LFPGGR---HELRRNIAVTTSMSCTDFSFHF--PVCVQDLISPINVSLNFSLWEEEGTPR 658
LF R H I+ M C + + +D ++PI + + + L
Sbjct: 506 LFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRL-------- 557
Query: 659 DQRAGKD---IPPILR---PSLHSETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLT 712
D R D + PIL P+ S I + CGED C+ L VS + + + +
Sbjct: 558 DYRTAADTTGLQPILNQFTPANISRQAHILLD--CGEDNVCKPKLEVSVD-SDQKKIYIG 614
Query: 713 AFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLS 772
L++ + N E AY +L + P F V + + +SC E +
Sbjct: 615 DDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGV-VRNNEALARLSCAFKTENQ---T 670
Query: 773 RALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNN 818
R + C++ +P+ KAG + + F+ S SV+ + +N
Sbjct: 671 RQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSN 715
Score = 34.3 bits (77), Expect = 0.66
Identities = 13/30 (43%), Positives = 24/30 (80%)
Query: 1006 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1035
+++ +L+ + GLLLL ++ V+Y++GFFKR
Sbjct: 958 VWVIILAVLAGLLLLAVLVFVMYRMGFFKR 987
>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
sapiens]
Length = 462
Score = 110 bits (275), Expect = 7e-24
Identities = 121/441 (27%), Positives = 180/441 (40%), Gaps = 78/441 (17%)
Query: 678 TWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDL 737
T +PFEKNCG D C+ NL +SFS ++L + + L+ E+ + N ED+Y +
Sbjct: 11 TASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITF 70
Query: 738 HFPPGLSFRKVEMLKPHSQ---IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQM 794
P GLS+R V + Q + ++C+ P S+ + + SC ++ IF+ G +
Sbjct: 71 SHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQ-GTWSTSCRINHLIFRGGAQITFLA 129
Query: 795 MFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTI---IPILYPINILIQDQEDSTL 851
F+ + GD + L ANV+ N S TT +P+ Y + ++ E T
Sbjct: 130 TFDVSPKAVLGDRLLLTANVSSENN----TPRTSKTTFQLELPVKYAVYTVVSSHEQFTK 185
Query: 852 YVSFTPKGPK-IHQVKHMYQV----------------RIQPSIHDHNIPT--------LE 886
Y++F+ K H H YQ R P + +P ++
Sbjct: 186 YLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMD 245
Query: 887 AVVGVPQPPSE------------GPITHQW--SVQMEPPVPCHYEDLERLPDAAEPCLPG 932
V PQ P + + W V E V C + L ++E P
Sbjct: 246 VEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIAPP 305
Query: 933 A---------------------LFRCPV---VFRQEILVQVIGTLEL--VGEIEASSMFS 966
A FRC V ++E+ + G L V +I S
Sbjct: 306 ASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQI-LQKKVS 364
Query: 967 LCSSLSISFNSSKHFHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFI 1025
+ S I+F++S + L G A + AQ ++ L V S IGGLLLL LI
Sbjct: 365 VVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITA 424
Query: 1026 VLYKVGFFKRNLKEKMEAGRG 1046
VLYKVGFFKR KE ME G
Sbjct: 425 VLYKVGFFKRQYKEMMEEANG 445
>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
Length = 496
Score = 70.1 bits (170), Expect = 1e-11
Identities = 61/215 (28%), Positives = 96/215 (44%), Gaps = 15/215 (6%)
Query: 44 HFGYRVLQVGNGVIVGAPGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLAT-D 102
H G+ + G V + G G+S L G+ P K++ + T D
Sbjct: 250 HEGFTLNSDGKTCNVCSGGGGSSATDLVFLIDGSKSVRPENFE---LVKKFISQIVDTLD 306
Query: 103 PTDGSILFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVF 162
+D VQ+S+S + EF + +KD A ++++ +M T T A+ Y+ F
Sbjct: 307 VSDKLAQVGLVQYSSSVRQEFPLGRFHTKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSF 366
Query: 163 REELGARPDATKVLIIITDGEATDSGNIDAAK-----DIIRYIIGIGKHFQTKESQETLH 217
GARP A KV I+ TDG + D N DAAK + +G+G ++ L
Sbjct: 367 TVSSGARPGAQKVGIVFTDGRSQDYIN-DAAKKAKDLGFKMFAVGVG-----NAVEDELR 420
Query: 218 KFASKPASEFVKILDTFEKLKDLFTELQKKIYVIE 252
+ AS+P +E F+ + + +LQKKI V E
Sbjct: 421 EIASEPVAEHYFYTADFKTINQIGKKLQKKICVEE 455
Score = 52.8 bits (125), Expect = 2e-06
Identities = 38/146 (26%), Positives = 73/146 (50%), Gaps = 12/146 (8%)
Query: 113 VQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGAR--- 169
V ++++ K EF +V + ++ ++ + T T AI + T+ F + G R
Sbjct: 83 VNYASTVKQEFSLRAHVSKAALLQAVRRIQPLSTGTMTGLAIQFAITKAFGDAEGGRSRS 142
Query: 170 PDATKVLIIITDGEATDS-GNIDA---AKDIIRYIIGIGKHFQTKESQETLHKFASKPAS 225
PD +KV+I++TDG DS ++ A A + + IG+G + TL + AS+P
Sbjct: 143 PDISKVVIVVTDGRPQDSVQDVSARARASGVELFAIGVG-----SVDKATLRQIASEPQD 197
Query: 226 EFVKILDTFEKLKDLFTELQKKIYVI 251
E V ++++ ++ L + Q+ V+
Sbjct: 198 EHVDYVESYSVIEKLSRKFQEAFCVV 223
>gi|29171717 glycosylphosphatidylinositol specific phospholipase D1
isoform 1 precursor [Homo sapiens]
Length = 840
Score = 64.7 bits (156), Expect = 5e-10
Identities = 59/187 (31%), Positives = 88/187 (47%), Gaps = 32/187 (17%)
Query: 358 GGGHWSQVQTIHGTQIGSYF--------GGELCGVDVDQDGETELLLIGAPLFY--GEQR 407
GG SQ + + SYF G + D++QDG +L+ +GAP + G
Sbjct: 356 GGSQLSQKHV--SSPLASYFLSFPYARLGWAMTSADLNQDGHGDLV-VGAPGYSRPGHIH 412
Query: 408 GGRVFIYQRRQLGFEEVS-ELQGDP-----GY-PLGRFGEAITALTDINGDGLVDVAVGA 460
GRV++ LG V +L + G+ P GRFG A+ L D N DG+ D+AVGA
Sbjct: 413 IGRVYLIYGNDLGLPPVDLDLDKEAHRILEGFQPSGRFGSALAVL-DFNVDGVPDLAVGA 471
Query: 461 P------LEEQGAVYI-FNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGL 513
P L +GAVY+ F + GG+S P+ I + + W + D+ GD
Sbjct: 472 PSVGSEQLTYKGAVYVYFGSKQGGMSSSPNITISCQDIYCNLGWTLLA----ADVNGDSE 527
Query: 514 ADVAVGA 520
D+ +G+
Sbjct: 528 PDLVIGS 534
Score = 47.0 bits (110), Expect = 1e-04
Identities = 38/99 (38%), Positives = 49/99 (49%), Gaps = 10/99 (10%)
Query: 433 YPLGRFGEAITALTDINGDGLVDVAVGAPLEEQ------GAVYIFNGRHGGLSPQPSQRI 486
+P R G A+T+ D+N DG D+ VGAP + G VY+ G GL P
Sbjct: 376 FPYARLGWAMTS-ADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLD 434
Query: 487 -EGTQVLSGIQWFGR--SIHGVKDLEGDGLADVAVGAES 522
E ++L G Q GR S V D DG+ D+AVGA S
Sbjct: 435 KEAHRILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAPS 473
Score = 40.0 bits (92), Expect = 0.012
Identities = 52/198 (26%), Positives = 76/198 (38%), Gaps = 37/198 (18%)
Query: 337 LASGAPRYQ-----HMGRVLLFQEPQGGGHWSQV-------QTIHGTQIGSYFGGELCGV 384
L GAP Y H+GRV L G + + + G Q FG L +
Sbjct: 398 LVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLDKEAHRILEGFQPSGRFGSALAVL 457
Query: 385 DVDQDGETELLLIGAPLFYGEQRG--GRVFIYQRRQLGFEEVSELQGDPGYPLG------ 436
D + DG +L +GAP EQ G V++Y + G + P +
Sbjct: 458 DFNVDGVPDLA-VGAPSVGSEQLTYKGAVYVYFGSKQG-----GMSSSPNITISCQDIYC 511
Query: 437 RFGEAITALTDINGDGLVDVAVGAPL-----EEQGAVYIFNGRHGGLSPQPSQRIEGTQV 491
G + A D+NGD D+ +G+P +++G V F LS + +E
Sbjct: 512 NLGWTLLA-ADVNGDSEPDLVIGSPFAPGGGKQKGIVAAFYS-GPSLSDKEKLNVEAANW 569
Query: 492 L----SGIQWFGRSIHGV 505
WFG S+HGV
Sbjct: 570 TVRGEEDFSWFGYSLHGV 587
Score = 35.4 bits (80), Expect = 0.29
Identities = 47/193 (24%), Positives = 80/193 (41%), Gaps = 45/193 (23%)
Query: 320 YLGYTVTWLPSRQKTSLLASGAPRYQH---MGRVLLFQE------------PQGGGHWSQ 364
+ GY++ + +T LL G+P +++ +G +L ++ P G W
Sbjct: 579 WFGYSLHGVTVDNRTLLLV-GSPTWKNASRLGHLLHIRDEKKSLGRVYGYFPPNGQSWF- 636
Query: 365 VQTIHGTQIGSYFGGELCGVDVDQDGET-ELLLIGAPLFYGEQR----------GGRVFI 413
TI G + G L V +G ++LL+GAP + + GG +
Sbjct: 637 --TISGDKAMGKLGTSLSSGHVLMNGTLKQVLLVGAPTYDDVSKVAFLTVTLHQGGATRM 694
Query: 414 YQRRQLGFEEV-SELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLE--------- 463
Y + S GD + RFG + L+D++ DGL ++ + APL
Sbjct: 695 YALTSDAQPLLLSTFSGDRRF--SRFG-GVLHLSDLDDDGLDEIIMAAPLRIADVTSGLI 751
Query: 464 --EQGAVYIFNGR 474
E G VY++NG+
Sbjct: 752 GGEDGRVYVYNGK 764
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 61.2 bits (147), Expect = 5e-09
Identities = 41/143 (28%), Positives = 72/143 (50%), Gaps = 12/143 (8%)
Query: 113 VQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARP-- 170
+Q+ ++ K EF + ++ + + +K ++H+ T T AI Y F E GARP
Sbjct: 99 LQYGSTVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLR 158
Query: 171 -DATKVLIIITDGEATDSGNIDAAK----DIIRYIIGIGKHFQTKESQETLHKFASKPAS 225
+ +V++I+TDG DS AAK I+ + IG+G + TL S+P
Sbjct: 159 ENVPRVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVG-----QVDFNTLKSIGSEPHE 213
Query: 226 EFVKILDTFEKLKDLFTELQKKI 248
+ V ++ F +++ L + QKK+
Sbjct: 214 DHVFLVANFSQIETLTSVFQKKL 236
Score = 58.9 bits (141), Expect = 2e-08
Identities = 42/143 (29%), Positives = 73/143 (51%), Gaps = 12/143 (8%)
Query: 113 VQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDA 172
+Q+ST TEF ++ KD + H+K+M + T A+ ++ F + GARP +
Sbjct: 697 LQYSTQVHTEFTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLS 756
Query: 173 TKV---LIIITDGEATDSGNIDAAK----DIIRYIIGIGKHFQTKESQETLHKFASKPAS 225
T+V I+ TDG A D + A+K I Y +G+GK +E L + AS+P +
Sbjct: 757 TRVPRAAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAI-----EEELQEIASEPTN 811
Query: 226 EFVKILDTFEKLKDLFTELQKKI 248
+ + + F + ++ +L+K I
Sbjct: 812 KHLFYAEDFSTMDEISEKLKKGI 834
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,916,744
Number of Sequences: 37866
Number of extensions: 2172645
Number of successful extensions: 5181
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 4803
Number of HSP's gapped (non-prelim): 166
length of query: 1086
length of database: 18,247,518
effective HSP length: 113
effective length of query: 973
effective length of database: 13,968,660
effective search space: 13591506180
effective search space used: 13591506180
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.