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Search of human proteins with 167466215
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167466215 integrin alpha L isoform a precursor [Homo
sapiens]
(1170 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 2355 0.0
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 1956 0.0
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 577 e-164
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 576 e-164
gi|34452173 integrin alpha X precursor [Homo sapiens] 555 e-157
gi|62548866 integrin, alpha D precursor [Homo sapiens] 540 e-153
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 392 e-108
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 386 e-107
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 380 e-105
gi|148728188 integrin, alpha E precursor [Homo sapiens] 340 6e-93
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 333 7e-91
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 213 9e-55
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 195 2e-49
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 173 8e-43
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 173 8e-43
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 162 2e-39
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 159 1e-38
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 159 1e-38
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 152 1e-36
gi|49170034 integrin, alpha 8 [Homo sapiens] 141 4e-33
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 139 2e-32
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 139 2e-32
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 138 3e-32
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 121 3e-27
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 121 3e-27
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 119 2e-26
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 110 8e-24
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 90 1e-17
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 84 6e-16
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 84 6e-16
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 2355 bits (6103), Expect = 0.0
Identities = 1170/1170 (100%), Positives = 1170/1170 (100%)
Query: 1 MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGA 60
MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGA
Sbjct: 1 MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGA 60
Query: 61 PGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILACDPGLSRTCD 120
PGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILACDPGLSRTCD
Sbjct: 61 PGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILACDPGLSRTCD 120
Query: 121 QNTYLSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMK 180
QNTYLSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMK
Sbjct: 121 QNTYLSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMK 180
Query: 181 DVMKKLSNTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYV 240
DVMKKLSNTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYV
Sbjct: 181 DVMKKLSNTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYV 240
Query: 241 ATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLH 300
ATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLH
Sbjct: 241 ATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLH 300
Query: 301 KFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSR 360
KFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSR
Sbjct: 301 KFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSR 360
Query: 361 GHAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLL 420
GHAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLL
Sbjct: 361 GHAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLL 420
Query: 421 ASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLI 480
ASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLI
Sbjct: 421 ASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLI 480
Query: 481 GAPLFYGEQRGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVA 540
GAPLFYGEQRGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVA
Sbjct: 481 GAPLFYGEQRGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVA 540
Query: 541 VGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVA 600
VGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVA
Sbjct: 541 VGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVA 600
Query: 601 VGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLI 660
VGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLI
Sbjct: 601 VGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLI 660
Query: 661 PQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQD 720
PQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQD
Sbjct: 661 PQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQD 720
Query: 721 LISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEAN 780
LISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEAN
Sbjct: 721 LISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEAN 780
Query: 781 LRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQ 840
LRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQ
Sbjct: 781 LRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQ 840
Query: 841 IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC 900
IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC
Sbjct: 841 IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC 900
Query: 901 NNEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPS 960
NNEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPS
Sbjct: 901 NNEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPS 960
Query: 961 IHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFR 1020
IHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFR
Sbjct: 961 IHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFR 1020
Query: 1021 CPVVFRQEILVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMK 1080
CPVVFRQEILVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMK
Sbjct: 1021 CPVVFRQEILVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMK 1080
Query: 1081 VDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDS 1140
VDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDS
Sbjct: 1081 VDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDS 1140
Query: 1141 EQLASGQEAGDPGCLKPLHEKDSESGGGKD 1170
EQLASGQEAGDPGCLKPLHEKDSESGGGKD
Sbjct: 1141 EQLASGQEAGDPGCLKPLHEKDSESGGGKD 1170
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 1956 bits (5067), Expect = 0.0
Identities = 978/981 (99%), Positives = 978/981 (99%), Gaps = 1/981 (0%)
Query: 190 SYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREEL 249
S FAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREEL
Sbjct: 107 SILFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREEL 166
Query: 250 GARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASE 309
GARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASE
Sbjct: 167 GARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASE 226
Query: 310 FVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVG 369
FVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVG
Sbjct: 227 FVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVG 286
Query: 370 AKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQH 429
AKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQH
Sbjct: 287 AKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQH 346
Query: 430 MGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQ 489
MGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQ
Sbjct: 347 MGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQ 406
Query: 490 RGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQG 549
RGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQG
Sbjct: 407 RGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQG 466
Query: 550 AVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIV 609
AVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIV
Sbjct: 467 AVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIV 526
Query: 610 LSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVA 669
LSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVA
Sbjct: 527 LSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVA 586
Query: 670 NLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSL 729
NLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSL
Sbjct: 587 NLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSL 646
Query: 730 NFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPAR 789
NFSLWEEEGTPRDQRA GKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPAR
Sbjct: 647 NFSLWEEEGTPRDQRA-GKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPAR 705
Query: 790 SRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELP 849
SRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELP
Sbjct: 706 SRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELP 765
Query: 850 EESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLE 909
EESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLE
Sbjct: 766 EESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLE 825
Query: 910 DNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTL 969
DNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTL
Sbjct: 826 DNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTL 885
Query: 970 EAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEI 1029
EAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEI
Sbjct: 886 EAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEI 945
Query: 1030 LVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQM 1089
LVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQM
Sbjct: 946 LVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQM 1005
Query: 1090 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEA 1149
LYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEA
Sbjct: 1006 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEA 1065
Query: 1150 GDPGCLKPLHEKDSESGGGKD 1170
GDPGCLKPLHEKDSESGGGKD
Sbjct: 1066 GDPGCLKPLHEKDSESGGGKD 1086
Score = 225 bits (574), Expect = 2e-58
Identities = 109/109 (100%), Positives = 109/109 (100%)
Query: 1 MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGA 60
MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGA
Sbjct: 1 MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGA 60
Query: 61 PGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSIL 109
PGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSIL
Sbjct: 61 PGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSIL 109
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 577 bits (1487), Expect = e-164
Identities = 393/1155 (34%), Positives = 603/1155 (52%), Gaps = 64/1155 (5%)
Query: 26 YNLDVRGARSFSPPRAGRHFGYRVLQV-GNGVIVGAPGE---GNSTGSLYQCQSGTGHCL 81
+NLD A +F G FG V+Q+ G+ V+VGAP E N GSLYQC TG C
Sbjct: 17 FNLDTENAMTFQENARG--FGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQCDYSTGSCE 74
Query: 82 PVTLRGS-NYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNTYLSGLCYLFRQNLQGPM 140
P+ L+ + LG++LA + +LAC P + +TC +NTY+ GLC+LF NL+
Sbjct: 75 PIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCFLFGSNLRQQP 134
Query: 141 LQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFST 200
+ + C + + D+ FL DGS S+ P +F+++ +F+ VM++L + F+ +Q+S
Sbjct: 135 QKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSE 194
Query: 201 SYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLI 260
++ F F ++ +P +L+K + +L T+T I V E+F GAR +A K+L+
Sbjct: 195 EFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILV 254
Query: 261 IITDGE--ATDSGNIDAAKD-----IIRYIIGIGKHFQTKESQETLHKFASKPASEFVKI 313
+ITDGE G D + +IRY+IG+G F++++S++ L+ ASKP + V
Sbjct: 255 VITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQ 314
Query: 314 LDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDW 373
++ FE LK + +L++KI+ IEGT +SF E+S G SA ++ ++ VG+ DW
Sbjct: 315 VNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSYDW 374
Query: 374 AGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRV 433
AGG L + TFI + ++ YLGY + R + L GAPRYQH+G V
Sbjct: 375 AGGVF-LYTSKEKSTFINMTRVDSDMNDAYLGYAAA-IILRNRVQSLVLGAPRYQHIGLV 432
Query: 434 LLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGR 493
+F+ Q G W + GTQIG+YFG LC VDVD +G T+L+LIGAP +Y + RGG+
Sbjct: 433 AMFR--QNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQ 490
Query: 494 VFI--YQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE--QG 549
V + R + ++ + L G+ G P GRFG A+T L D+NGD L DVA+GAP EE +G
Sbjct: 491 VSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRG 550
Query: 550 AVYIFNGRHG-GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMI 608
AVY+F+G G G+SP SQRI G+++ +Q+FG+S+ G +DL DGL D+ VGA+ ++
Sbjct: 551 AVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVL 610
Query: 609 VLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI-KSLIPQF-QGR 666
+L S+PV+ + +M F+P E+ + EC+ K KE + +C + KS + +G+
Sbjct: 611 LLRSQPVLRVKAIMEFNPREVARNVFECNDQVV-KGKEAGEVRVCLHVQKSTRDRLREGQ 669
Query: 667 LVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVT-TSMSCTDFSFHFPVCVQDLISPI 725
+ + +TY L LD R R +F ++ RR V + +C P C++D +SPI
Sbjct: 670 IQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPI 729
Query: 726 NVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSF 785
+ LNFSL GTP A G P + + T PFEKNCG D C+ +L ++F
Sbjct: 730 VLRLNFSL---VGTPLS--AFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITF 784
Query: 786 SPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEML---KPHSQIP 842
S L + +V +++ N ED+Y Q+ FP LS+RKV L +
Sbjct: 785 SFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR 844
Query: 843 VSCEELPE-ESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCN 901
++CE E ++ SC+++ PIF V + F+ +S G+ + L ANVT
Sbjct: 845 LACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSE 904
Query: 902 NEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSI 961
N + +P+ Y + +++ ST Y++FT ++H YQV ++
Sbjct: 905 N-NMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQV---SNL 960
Query: 962 HDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRC 1021
++P + V VP ++ I + V + ERLP ++ L +
Sbjct: 961 GQRSLP-ISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSD--FLAELRKA 1017
Query: 1022 PVV------------------FRQEILVQVIGTLELVGEIEAS-SMFSLCSSLSISFNSS 1062
PVV ++E + G L I+ S + + S+ I FN S
Sbjct: 1018 PVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDS 1077
Query: 1063 KHFHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNL 1121
L G A + +Q KV+ L L V S +GGLLLL LI LYK+GFFKR
Sbjct: 1078 VFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQY 1137
Query: 1122 KEKMEAGRGVPNGIP 1136
K+ M G G P P
Sbjct: 1138 KDMMSEG-GPPGAEP 1151
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 576 bits (1484), Expect = e-164
Identities = 395/1158 (34%), Positives = 603/1158 (52%), Gaps = 69/1158 (5%)
Query: 26 YNLDVRGARSFSPPRAGRHFGYRVLQV-GNGVIVGAPGE---GNSTGSLYQCQSGTGHCL 81
+NLD A +F G FG V+Q+ G+ V+VGAP E N GSLYQC TG C
Sbjct: 17 FNLDTENAMTFQENARG--FGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQCDYSTGSCE 74
Query: 82 PVTLRGS-NYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNTYLSGLCYLFRQNLQGPM 140
P+ L+ + LG++LA + +LAC P + +TC +NTY+ GLC+LF NL+
Sbjct: 75 PIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCFLFGSNLRQQP 134
Query: 141 LQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFST 200
+ + C + + D+ FL DGS S+ P +F+++ +F+ VM++L + F+ +Q+S
Sbjct: 135 QKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSE 194
Query: 201 SYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLI 260
++ F F ++ +P +L+K + +L T+T I V E+F GAR +A K+L+
Sbjct: 195 EFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILV 254
Query: 261 IITDGE--ATDSGNIDAAKD-----IIRYIIGIGKHFQTKESQETLHKFASKPASEFVKI 313
+ITDGE G D + +IRY+IG+G F++++S++ L+ ASKP + V
Sbjct: 255 VITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQ 314
Query: 314 LDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDW 373
++ FE LK + +L++KI+ IEGT +SF E+S G SA ++ ++ VG+ DW
Sbjct: 315 VNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSYDW 374
Query: 374 AGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRV 433
AGG L + TFI + ++ YLGY + R + L GAPRYQH+G V
Sbjct: 375 AGGVF-LYTSKEKSTFINMTRVDSDMNDAYLGYAAA-IILRNRVQSLVLGAPRYQHIGLV 432
Query: 434 LLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGR 493
+F+ Q G W + GTQIG+YFG LC VDVD +G T+L+LIGAP +Y + RGG+
Sbjct: 433 AMFR--QNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQ 490
Query: 494 VFIY-----QRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE- 547
V + QR + + V L G+ G P GRFG A+T L D+NGD L DVA+GAP EE
Sbjct: 491 VSVCPLPRGQRARWQCDAV--LYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEED 548
Query: 548 -QGAVYIFNGRHG-GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAES 605
+GAVY+F+G G G+SP SQRI G+++ +Q+FG+S+ G +DL DGL D+ VGA+
Sbjct: 549 NRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQG 608
Query: 606 QMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI-KSLIPQF- 663
+++L S+PV+ + +M F+P E+ + EC+ K KE + +C + KS +
Sbjct: 609 HVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVV-KGKEAGEVRVCLHVQKSTRDRLR 667
Query: 664 QGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVT-TSMSCTDFSFHFPVCVQDLI 722
+G++ + +TY L LD R R +F ++ RR V + +C P C++D +
Sbjct: 668 EGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPV 727
Query: 723 SPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLR 782
SPI + LNFSL GTP A G P + + T PFEKNCG D C+ +L
Sbjct: 728 SPIVLRLNFSL---VGTPLS--AFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLS 782
Query: 783 VSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEML---KPHS 839
++FS L + +V +++ N ED+Y Q+ FP LS+RKV L +
Sbjct: 783 ITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQR 842
Query: 840 QIPVSCEELPE-ESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANV 898
++CE E ++ SC+++ PIF V + F+ +S G+ + L ANV
Sbjct: 843 SWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANV 902
Query: 899 TCNNEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQ 958
T N + +P+ Y + +++ ST Y++FT ++H YQV
Sbjct: 903 TSEN-NMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQV--- 958
Query: 959 PSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGAL 1018
++ ++P + V VP ++ I + V + ERLP ++ L
Sbjct: 959 SNLGQRSLP-ISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSD--FLAEL 1015
Query: 1019 FRCPVV------------------FRQEILVQVIGTLELVGEIEAS-SMFSLCSSLSISF 1059
+ PVV ++E + G L I+ S + + S+ I F
Sbjct: 1016 RKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILF 1075
Query: 1060 NSSKHFHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFK 1118
N S L G A + +Q KV+ L L V S +GGLLLL LI LYK+GFFK
Sbjct: 1076 NDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFK 1135
Query: 1119 RNLKEKMEAGRGVPNGIP 1136
R K+ M G G P P
Sbjct: 1136 RQYKDMMSEG-GPPGAEP 1152
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 555 bits (1429), Expect = e-157
Identities = 413/1177 (35%), Positives = 601/1177 (51%), Gaps = 94/1177 (7%)
Query: 12 ALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNG-VIVGAPGE---GNST 67
A L F A + +NLD +F AG FG V+Q N V+VGAP + N T
Sbjct: 6 AALLLFTALATSLGFNLDTEELTAFRVDSAG--FGDSVVQYANSWVVVGAPQKITAANQT 63
Query: 68 GSLYQCQSGTGHCLPVTLR-GSNYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNTYLS 126
G LYQC TG C P+ L+ + LG++LA+ + +LAC P + C +N YL+
Sbjct: 64 GGLYQCGYSTGACEPIGLQVPPEAVNMSLGLSLASTTSPSQLLACGPTVHHECGRNMYLT 123
Query: 127 GLCYLFRQNLQGP--MLQGRP-GFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVM 183
GLC+L GP + Q P QEC + D+VFL DGS S+ F +++F++ V+
Sbjct: 124 GLCFLL-----GPTQLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVI 178
Query: 184 KKLSNTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATE 243
+ S QF+ +QFS ++T F F ++ + +P +LL V + T T AI V
Sbjct: 179 SQFQRPSTQFSLMQFSNKFQTHFTFEEFRRSSNPLSLLASVHQLQGFTYTATAIQNVVHR 238
Query: 244 VFREELGARPDATKVLIIITDGEATDSGNID--------AAKDIIRYIIGIGKHFQTKES 295
+F GAR DA K+LI+ITDG+ + ++D A IIRY IG+G FQ + S
Sbjct: 239 LFHASYGARRDAAKILIVITDGK-KEGDSLDYKDVIPMADAAGIIRYAIGVGLAFQNRNS 297
Query: 296 QETLHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGIS 355
+ L+ ASKP+ E + ++ F+ LKD+ +L++KI+ IEGT +SF +E++ G S
Sbjct: 298 WKELNDIASKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFS 357
Query: 356 ADLSRGHAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQ 415
A + V+GAVG+ W+GG L TFI ++R YLGY+ T L +
Sbjct: 358 AVFTPDGPVLGAVGSFTWSGGAF-LYPPNMSPTFINMSQENVDMRDSYLGYS-TELALWK 415
Query: 416 KTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGET 475
L GAPRYQH G+ ++F Q W + GTQIGSYFG LC VDVD DG T
Sbjct: 416 GVQSLVLGAPRYQHTGKAVIF--TQVSRQWRMKAEVTGTQIGSYFGASLCSVDVDSDGST 473
Query: 476 ELLLIGAPLFYGEQRGGRVFI--YQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDING 533
+L+LIGAP +Y + RGG+V + R + + L G+ G+P GRFG A+T L D+NG
Sbjct: 474 DLVLIGAPHYYEQTRGGQVSVCPLPRGWRRWWCDAVLYGEQGHPWGRFGAALTVLGDVNG 533
Query: 534 DGLVDVAVGAPLEEQ--GAVYIFNGRHG-GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKD 590
D L DV +GAP EE+ GAVY+F+G G +SP SQRI G+Q+ S +Q+FG+++ G +D
Sbjct: 534 DKLTDVVIGAPGEEENRGAVYLFHGVLGPSISPSHSQRIAGSQLSSRLQYFGQALSGGQD 593
Query: 591 LEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNI 650
L DGL D+AVGA Q+++L +RPV+ + M F PAEIP EC ++ + V
Sbjct: 594 LTQDGLVDLAVGARGQVLLLRTRPVLWVGVSMQFIPAEIPRSAFECREQVVSE-QTLVQS 652
Query: 651 TICFQIKSLIPQFQGR--LVANLTYTLQLDGHRTRRRGLFPGGRH-ELRRNIAVTTSMSC 707
IC I G L +++T L LD R R F ++ L R + C
Sbjct: 653 NICLYIDKRSKNLLGSRDLQSSVTLDLALDPGRLSPRATFQETKNRSLSRVRVLGLKAHC 712
Query: 708 TDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAQGKDIPPI--LRPSLHSE---- 761
+F+ P CV+D ++PI + LNF+L GK + LRP L ++
Sbjct: 713 ENFNLLLPSCVEDSVTPITLRLNFTL------------VGKPLLAFRNLRPMLAADAQRY 760
Query: 762 -TWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLD 820
T +PFEKNCG D C+ NL +SFS ++L + + L+ E+ + N ED+Y +
Sbjct: 761 FTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTIT 820
Query: 821 LHFPPGLSFRKVEMLKPHSQ---IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQ 877
P GLS+R V + Q + ++C+ P S+ + + SC ++ IF+ G +
Sbjct: 821 FSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQ-GTWSTSCRINHLIFRGGAQITFL 879
Query: 878 MMFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTI---IPILYPINILIQDQEDST 934
F+ + GD + L ANV+ N S TT +P+ Y + ++ E T
Sbjct: 880 ATFDVSPKAVLGDRLLLTANVSSENN----TPRTSKTTFQLELPVKYAVYTVVSSHEQFT 935
Query: 935 LYVSFTPKGPK-IHQVKHMYQV-----RIQPSIHDHNIPT--------LEAVVGVPQPPS 980
Y++F+ K H H YQV R P + +P ++ V PQ PS
Sbjct: 936 KYLNFSESEEKESHVAMHRYQVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSHPQNPS 995
Query: 981 EGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGAL-FRCPV---VFRQEILVQVIGT 1036
S ++ PP +++ P + + G L FRC V ++E+ + G
Sbjct: 996 ----LRCSSEKIAPPASDFLAHIQKNP-VLDCSIAGCLRFRCDVPSFSVQEELDFTLKGN 1050
Query: 1037 LEL--VGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASL-AQVVMKVDVVYEKQMLYLY 1093
L V +I S+ S I+F++S + L G A + AQ ++ L
Sbjct: 1051 LSFGWVRQI-LQKKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLI 1109
Query: 1094 VLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRG 1130
V S IGGLLLL LI VLYKVGFFKR KE ME G
Sbjct: 1110 VGSSIGGLLLLALITAVLYKVGFFKRQYKEMMEEANG 1146
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 540 bits (1392), Expect = e-153
Identities = 394/1165 (33%), Positives = 604/1165 (51%), Gaps = 77/1165 (6%)
Query: 7 TVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNG-VIVGAPGE-- 63
TV+ +++L+ + F NLDV F G FG V+Q G ++VGAP E
Sbjct: 5 TVLLLSVLASYHGF------NLDVEEPTIFQEDAGG--FGQSVVQFGGSRLVVGAPLEVV 56
Query: 64 -GNSTGSLYQCQSGTGHCLPVTLR-GSNYTSKYLGMTLATDPTDGSILACDPGLSRTCDQ 121
N TG LY C + TG C P+ L + LG+TLA +LAC P L R C +
Sbjct: 57 AANQTGRLYDCAAATGMCQPIPLHIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGE 116
Query: 122 NTYLSGLCYLFRQNLQGPMLQGRP-GFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMK 180
N+Y G C L + ++Q P EC +D+VFL DGS S+ ++F ++ F++
Sbjct: 117 NSYSKGSCLLLGSRWE--IIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQ 174
Query: 181 DVMKKLSNTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYV 240
VM + T FA +Q+S K F F+ + +L+ + + LT T I V
Sbjct: 175 AVMGQFEGTDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTV 234
Query: 241 ATEVFREELGARPDATKVLIIITDG-------EATDSGNIDAAKDIIRYIIGIGKHFQTK 293
T++F + GAR A K+LI+ITDG E +D IIRY IG+G FQ
Sbjct: 235 VTQLFHHKNGARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGP 294
Query: 294 ESQETLHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSG 353
+++ L+ +S P + V +D F L + +LQ+KIY +EGT + +SF E+S G
Sbjct: 295 TARQELNTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEG 354
Query: 354 ISADLSRGHAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPS 413
S L+ +GAVG+ W+GG L TFI ++R YLGY+ T L
Sbjct: 355 FSTALTMDGLFLGAVGSFSWSGGAF-LYPPNMSPTFINMSQENVDMRDSYLGYS-TELAL 412
Query: 414 RQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDG 473
+ L GAPRYQH G+ ++F Q W + + GTQIGSYFG LC VDVD DG
Sbjct: 413 WKGVQNLVLGAPRYQHTGKAVIF--TQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSDG 470
Query: 474 ETELLLIGAPLFYGEQRGGRVFI--YQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDI 531
T+L+LIGAP +Y + RGG+V + R ++ ++ + L+G+ G+P GRFG A+T L D+
Sbjct: 471 STDLILIGAPHYYEQTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDV 530
Query: 532 NGDGLVDVAVGAPLEEQ--GAVYIFNG-RHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGV 588
N D L+DVA+GAP E++ GAVY+F+G G+SP SQRI +Q+ +Q+FG+++ G
Sbjct: 531 NEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGG 590
Query: 589 KDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGV 648
+DL DGL D+AVGA Q+++L S PV+ + M FSP E+ C + ++ G
Sbjct: 591 QDLTQDGLMDLAVGARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAG- 649
Query: 649 NITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRH-ELRRNIAVTTSMSC 707
+ T+C I+ G + +++ + L LD R R +F ++ L R + + C
Sbjct: 650 DATVCLTIQKSSLDQLGDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHC 709
Query: 708 TDFSFHFPVCVQDLISPINVSLNFSLWEEE-GTPRDQRAQGKDIPPILRPSLHSETWEIP 766
P CV+D++SPI + LNFSL E +P++ R P + S T +P
Sbjct: 710 ETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQNLR------PVLAVGSQDLFTASLP 763
Query: 767 FEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPG 826
FEKNCG+D CE +L V+ S + + L + + L+V +++ N ED+Y + L++P G
Sbjct: 764 FEKNCGQDGLCEGDLGVTLSFSGLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAG 823
Query: 827 LSFRKVE--MLKPH-SQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTL 883
LS R+V +PH S + ++CE +P E L R+ C+V+ PIF G + + F+
Sbjct: 824 LSHRRVSGAQKQPHQSALRLACETVPTEDEGL-RSSRCSVNHPIFHEGSNGTFIVTFDVS 882
Query: 884 VNSSWGDSVELHANVTCNNEDSDLLEDNSATTI---IPILYPINILIQDQEDSTLYVSF- 939
++ GD + + A+ + N + +S T +P+ Y + +I QE+ST Y +F
Sbjct: 883 YKATLGDRMLMRASASSENNKA----SSSKATFQLELPVKYAVYTMISRQEESTKYFNFA 938
Query: 940 TPKGPKIHQVKHMYQVR------IQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQME 993
T K+ + +H Y+V + SI + +P L V V E P V
Sbjct: 939 TSDEKKMKEAEHRYRVNNLSQRDLAISI-NFWVPVLLNGVAVWDVVMEAPSQSLPCVSER 997
Query: 994 PPVPCHYEDLERLPDAAEPCLPGAL-----FRCPV---VFRQEILVQVIGTLELVGEIEA 1045
P P H + L ++ + P L ++ FRC V ++E+ + G L E
Sbjct: 998 KP-PQHSDFLTQI--SRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRET 1054
Query: 1046 SSMFSLCSSLS-ISFNSSKHFHLYGSNASL---AQVVMKVDVVYEKQMLYLYVLSGIGGL 1101
L S++ I+F++S + L G A + ++V++ D VY + + + S +G L
Sbjct: 1055 LQKKVLVVSVAEITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVY--NAIPIIMGSSVGAL 1112
Query: 1102 LLLLLIFIVLYKVGFFKRNLKEKME 1126
LLL LI LYK+GFFKR+ KE +E
Sbjct: 1113 LLLALITATLYKLGFFKRHYKEMLE 1137
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 392 bits (1007), Expect = e-108
Identities = 359/1222 (29%), Positives = 566/1222 (46%), Gaps = 149/1222 (12%)
Query: 6 ITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQ---VGNG-VIVGAP 61
+ A++L GF ++N+D R R R FGY V Q GN ++VGAP
Sbjct: 8 VVAWALSLWPGF-----TDTFNMDTRKPRVIPGSRTA-FFGYTVQQHDISGNKWLVVGAP 61
Query: 62 GEGNS---TGSLYQCQSGTGHCLPVTLRG---SNYTSKY----LGMTLATDPTDGSILAC 111
E N TG +Y+C G+C + L SN + + LG++LAT+P D S LAC
Sbjct: 62 LETNGYQKTGDVYKCPVIHGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLAC 121
Query: 112 DPGLSRTCDQNTYLSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDE 171
P S C + Y +G+C N + P Q C + +D+V + DGS S+ P
Sbjct: 122 SPLWSHECGSSYYTTGMCSRVNSNFRFSKTVA-PALQRC-QTYMDIVIVLDGSNSIYP-- 177
Query: 172 FQKILDFMKDVMKK--LSNTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHML- 228
+ ++ F+ +++KK + Q VQ+ EF +DY KD H++
Sbjct: 178 WVEVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGG 237
Query: 229 LLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAA------KDIIRY 282
T T I + +E F++ G R A KV+I+ITDGE+ DS +++ ++ RY
Sbjct: 238 TETRTAFGIEFARSEAFQK--GGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRY 295
Query: 283 IIGIGKHFQTKE-SQET----LHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGT 337
+ + ++ + + ET + AS P + + LKD+ L +I+ +EGT
Sbjct: 296 AVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGT 355
Query: 338 SKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWAGGFLDL----KADLQDDTFIGNE 393
+K + TSF +E+S +G S+ + ++GAVGA DW G L K ++++
Sbjct: 356 NKNE-TSFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEF 414
Query: 394 PLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIH- 452
P + YLGYTVT + S ++ + +GAPR+ H G+V+LF H ++ TIH
Sbjct: 415 PEELKNHGAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVILFTM-----HNNRSLTIHQ 469
Query: 453 ---GTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRG-GRVFIYQRRQLGFEEVS 508
G QIGSYFG E+ VD+D DG T++LL+GAP+++ E R G+V++Y+ RQ F
Sbjct: 470 AMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNG 529
Query: 509 ELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPS 566
L+ Y RFG +I ++ D+N D DV VGAPLE+ GA+YIF+G G + P
Sbjct: 530 TLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPK 589
Query: 567 QRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSP 626
QRI +++ +G+Q+FG SIHG DL DGL D+AVGA ++L SRPVV + + F P
Sbjct: 590 QRITASELATGLQYFGCSIHGQLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEP 649
Query: 627 AEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHR-TRRR 685
++I + +C S + + +CF L P FQ V + Y +D R T R
Sbjct: 650 SKINIFHRDC--KRSGRDATCLAAFLCFTPIFLAPHFQTTTV-GIRYNATMDERRYTPRA 706
Query: 686 GLFPGGRHELRRNIAVTTSMS-CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQR 744
L GG R + +++ C +FH + D + P+ S+ +SL + + P
Sbjct: 707 HLDEGGDRFTNRAVLLSSGQELCERINFHV-LDTADYVKPVTFSVEYSLEDPDHGP---- 761
Query: 745 AQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANL----------------RVSFSPA 788
P LR S +PF C ED+ C +L RV PA
Sbjct: 762 MLDDGWPTTLRVS-------VPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPA 814
Query: 789 RSRALRLTAFAS-----------LSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKP 837
+ + +F + ++VE +L N E+AY L++ L F + + K
Sbjct: 815 QDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASL-IQKE 873
Query: 838 HSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELH-- 895
S + C + EE RL + CNVS P F+A VA ++ F + S+ LH
Sbjct: 874 DSDGSIEC--VNEERRLQKQV--CNVSYPFFRAKAKVAFRLDF------EFSKSIFLHHL 923
Query: 896 ----ANVTCNNEDSDLLEDNSATTIIPILYPINIL-----------IQDQEDSTLYVSFT 940
A + +NE EDN A + Y ++L ++ Y
Sbjct: 924 EIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFTRSSSLSHYEVKPNSSLERYDGIG 983
Query: 941 PKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQ-------WSVQME 993
P I +++++ I + IP + G +T + W E
Sbjct: 984 PPFSCIFRIQNLGLFPIHGMMMKITIP-IATRSGNRLLKLRDFLTDEANTSCNIWGNSTE 1042
Query: 994 -PPVPCHYEDLERLPDAAEPCLPGALFRCPV--VFRQEILVQVIGTLELVGEIEASSMFS 1050
P P EDL R P C + V QEI ++G L L ++A S
Sbjct: 1043 YRPTPVE-EDLRRAPQLNHSNSDVVSINCNIRLVPNQEINFHLLGNLWL-RSLKALKYKS 1100
Query: 1051 LCSSLSISFNSSKHFH---LYGSNASLAQVVMKVDVVYEKQM-LYLYVLSGIGGLLLLLL 1106
+ + ++ + FH ++ Q+V ++ + Q+ +++ V S +GGLLLL L
Sbjct: 1101 M--KIMVNAALQRQFHSPFIFREEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLAL 1158
Query: 1107 IFIVLYKVGFFKRNLKEKMEAG 1128
+ + L+K+GFF R+ + + E G
Sbjct: 1159 LVLALWKLGFF-RSARRRREPG 1179
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 386 bits (992), Expect = e-107
Identities = 338/1201 (28%), Positives = 554/1201 (46%), Gaps = 149/1201 (12%)
Query: 25 SYNLDVRGARSFSPPRAGRHFGYRVLQV----GNGVIVGAPGEG---NSTGSLYQCQSGT 77
S+N+DV+ + +FS P FGY V Q G V++G+P G N TG +Y+C G
Sbjct: 28 SFNVDVKNSMTFSGPVEDM-FGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGR 86
Query: 78 GHCLP--------------VTLRGSNYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNT 123
G LP VT N T G TL T+P +G LAC P + C
Sbjct: 87 GESLPCVKLDLPVNTSIPNVTEVKENMT---FGSTLVTNP-NGGFLACGPLYAYRCGHLH 142
Query: 124 YLSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVM 183
Y +G+C Q ++ QEC +D+V + DGS S+ P + + F+ D++
Sbjct: 143 YTTGICSDVSPTFQ--VVNSIAPVQEC-STQLDIVIVLDGSNSIYP--WDSVTAFLNDLL 197
Query: 184 KKLS--NTSYQFAAVQFSTSYKTEFDFSDYVKRKDP-DALLKHVKHMLLLTNTFGAINYV 240
+++ Q VQ+ + EF+ + Y ++ A K V+ T T I+
Sbjct: 198 ERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTA 257
Query: 241 ATEVFREELGARPDATKVLIIITDGEATDSGNIDAA------KDIIRYIIGI-----GKH 289
E F E GAR KV++I+TDGE+ D+ + ++I R+ I I +
Sbjct: 258 RKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGN 317
Query: 290 FQTKESQETLHKFASKPASE-FVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNME 348
T++ E + AS+P + F + D L + L ++I+ +E T+ Q SF ME
Sbjct: 318 LSTEKFVEEIKSIASEPTEKHFFNVSDELA-LVTIVKTLGERIFALEATADQSAASFEME 376
Query: 349 LSSSGISADLSRGHAVVGAVGAKDWAGGFLDLKADL----QDDTFIGNEPLTPEVRAGYL 404
+S +G SA S+ ++GAVGA DW G + KA ++ TF E A YL
Sbjct: 377 MSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYL 436
Query: 405 GYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGEL 464
GYTV + L +G PRY H G+V++++ G + +QT+ G QIGSYFG L
Sbjct: 437 GYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDG--NIKILQTLSGEQIGSYFGSIL 494
Query: 465 CGVDVDQDGETELLLIGAPLFYGEQRG--GRVFIYQRRQLGFEEVSELQG---------- 512
D+D+D T++LL+GAP++ G ++ G+V++Y Q FE L+
Sbjct: 495 TTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQ 554
Query: 513 -------DPGYPLG-RFGEAITALTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLS 562
+ P G RFG AI A+ D+N DG D+ +GAPLE+ GAVYI++G +
Sbjct: 555 HNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIR 614
Query: 563 PQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLM 622
+ +QRI +++FG+SIHG DL GDGL DV +G + SR V + M
Sbjct: 615 KEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTM 674
Query: 623 SFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRT 682
+F P ++ + + C K +N T+CF +K L + A+L Y + LD R
Sbjct: 675 NFEPNKVNIQKKNC--HMEGKETVCINATVCFDVK-LKSKEDTIYEADLQYRVTLDSLRQ 731
Query: 683 RRRGLFPGGR-HELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPR 741
R F G + +++RNI V S CT SF+ + D + ++L+F+L + E
Sbjct: 732 ISRSFFSGTQERKVQRNITVRKS-ECTKHSFYM-LDKHDFQDSVRITLDFNLTDPEN--- 786
Query: 742 DQRAQGKDIPPILRPSLHSETWE-IPFEKNCGEDKKCEANLRVSFSPARSRALRL-TAFA 799
P+L SL + E IPF K+CG +KC ++L + + L + +
Sbjct: 787 ---------GPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQND 837
Query: 800 SLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRAL 859
+V L++ N ++ AY + +H+ P L F +E ++ SCE + +
Sbjct: 838 KFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD-----SCES--------NHNI 884
Query: 860 SCNVSSPIFKAGHSVALQMMFNTLVNSSW-GDSVELHANVTCNNED-SDLLEDNSATTII 917
+C V P + G V +++F N+S+ ++V ++ + T ++E+ + L DN I
Sbjct: 885 TCKVGYPFLRRGEMVTFKILFQ--FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISI 942
Query: 918 PILYPINI-LIQDQEDSTLYVSFTPKGPKI--------HQVKHMYQVRIQPSIHDHNIPT 968
P+ Y + + + + ++ P++ +++ Y +R S +P
Sbjct: 943 PVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF---PMPE 999
Query: 969 LEAVVGVPQPPSEG-PITHQWSVQMEPPVPCH---YEDL------ERLPDAAEPCLPGAL 1018
L+ + P S G P+ + + C +ED +++ + + G +
Sbjct: 1000 LKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTI 1059
Query: 1019 FRCPVVFRQEILVQVIGTLELVGEIEASSMF---SLCSSLSISFNSSKHFHLYGSNASLA 1075
C I + T + ++ S + + S S N + L NASL
Sbjct: 1060 LDCNTCKFATITCNL--TSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLV 1117
Query: 1076 ----------QVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKM 1125
+ + D + + L++ +LS GLLLL+L+ + L+K+GFFKR LK+KM
Sbjct: 1118 LSSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKM 1177
Query: 1126 E 1126
E
Sbjct: 1178 E 1178
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 380 bits (975), Expect = e-105
Identities = 348/1185 (29%), Positives = 543/1185 (45%), Gaps = 134/1185 (11%)
Query: 18 FFFAPASSYNLDVRGARSF-SPPRAGRHFGYRVLQ-VGNG---VIVGAPGEGNS---TGS 69
F S +NLD R F PP A FGY VLQ VG G ++VGAP +G S G
Sbjct: 15 FLTGLCSPFNLDEHHPRLFPGPPEA--EFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGD 72
Query: 70 LYQCQSGTGHCLPVT--------LRGSNY--TSKYLGMTLATDPTDGSILACDPGLSRTC 119
+Y+C G H P L S++ + +LGM+L DG +AC P SR C
Sbjct: 73 VYRCPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGFMACAPLWSRAC 132
Query: 120 DQNTYLSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFM 179
+ + SG+C + Q P P Q C +D+V + DGS S+ P + ++ F+
Sbjct: 133 GSSVFSSGICARVDASFQ-PQGSLAPTAQRC-PTYMDVVIVLDGSNSIYP--WSEVQTFL 188
Query: 180 KDVMKKL--SNTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHML-LLTNTFGA 236
+ ++ KL Q VQ+ S E+ D+ +++ K++ T T A
Sbjct: 189 RRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQA 248
Query: 237 INYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKD------IIRYIIGIGKHF 290
I TE F + G RP+A ++L+++TDGE+ D + AA + RY I + H+
Sbjct: 249 IMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRYGIAVLGHY 308
Query: 291 QTKESQET-----LHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSF 345
++ + + AS P F + L D+ L +I+ +EG+ ++ +SF
Sbjct: 309 LRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENESSF 368
Query: 346 NMELSSSGISADLSRGHAVVGAVGAKDWAGGFLDLKADLQ--------DDTFIGNEPLTP 397
+E+S G S + + G VGA DW G L L+ + +D F P
Sbjct: 369 GLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEF----PPAL 424
Query: 398 EVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIG 457
+ A YLGY+V+ + R L SGAPR++H G+V+ FQ + G Q++ G QIG
Sbjct: 425 QNHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAV-RVAQSLQGEQIG 483
Query: 458 SYFGGELCGVDVDQDGETELLLIGAPLFYGEQRG--GRVFIYQRRQLGFEEVSELQG--D 513
SYFG ELC +D D+DG T++LL+ AP+F G Q GRV++Y +G + + LQG
Sbjct: 484 SYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYL---VGQQSLLTLQGTLQ 540
Query: 514 PGYPL-GRFGEAITALTDINGDGLVDVAVGAPLEE--QGAVYIFNGRHGGLSPQPSQRIE 570
P P RFG A+ AL D+N DG DVAVGAPLE+ QGA+Y+++G G+ P P+QRI
Sbjct: 541 PEPPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIA 600
Query: 571 GTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIP 630
+ + +FGRS+ G DL+GD L DVAVGA+ I+LSSRP+V + + +P I
Sbjct: 601 AASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAIS 660
Query: 631 VHEVECSYSTSNKMKEGVNIT--ICFQIKSLIP-----QFQGRLVANLTYTLQLDGHRTR 683
V + +C + +E V +T +CFQ+ S P QF R +T LD
Sbjct: 661 VVQRDC----RRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMR------FTASLDEWTAG 710
Query: 684 RRGLFPGGRHEL--RRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPR 741
R F G L RR +++C FH + D + P+ +++ F+L + T +
Sbjct: 711 ARAAFDGSGQRLSPRRLRLSVGNVTCEQLHFHV-LDTSDYLRPVALTVTFAL---DNTTK 766
Query: 742 DQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFA-- 799
+ P ++ +PF K+CG D +C +L + + R R F
Sbjct: 767 PGPVLNEGSPTSIQKL-------VPFSKDCGPDNECVTDLVLQVN-MDIRGSRKAPFVVR 818
Query: 800 ----SLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLL 855
+ V +L N +E+AY L L F L + + S I V C +RL
Sbjct: 819 GGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQR-ESPIKVECAAPSAHARL- 876
Query: 856 SRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATT 915
C+V P+F+ G V + F +S + + E + L+DN+A T
Sbjct: 877 -----CSVGHPVFQTGAKVTFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQT 931
Query: 916 IIPILYPINILIQDQED---------STLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNI 966
I Y ++L + TL V P+ +V+++ + I +
Sbjct: 932 SAYIQYEPHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRVQNLGCYVVSGLIISALL 991
Query: 967 PTL----EAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLE---RLPDAAEPCLPGALF 1019
P + + + Q + ++ P P H E+L+ RL + C +
Sbjct: 992 PAVAHGGNYFLSLSQVITNNASCIVQNLTEPPGPPVHPEELQHTNRLNGSNTQC---QVV 1048
Query: 1020 RCPVVFRQEILVQVIGTLELV-GEIEASSMF---SLCSSLSISFNSSKHFHLYGS---NA 1072
RC + + +G L LV E + F ++ S+ + L + +
Sbjct: 1049 RCHLGQLAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSE 1108
Query: 1073 SLAQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFF 1117
SL +VV ++ L++ + S +GGLLLL L+ L+K+GFF
Sbjct: 1109 SLLEVVQTRPILIS---LWILIGSVLGGLLLLALLVFCLWKLGFF 1150
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 340 bits (871), Expect = 6e-93
Identities = 287/1023 (28%), Positives = 470/1023 (45%), Gaps = 113/1023 (11%)
Query: 152 KGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQ--FAAVQFSTSYKTEFDFS 209
+ ++ + DGS S+ P +FQ+ DF+ ++M+ ++ FA VQ+ +TEFD
Sbjct: 198 EAGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLR 257
Query: 210 DYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDG---- 265
D A ++++ + +T T A+ +V +F G+R A+KV++++TDG
Sbjct: 258 DSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFE 317
Query: 266 ---EATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKLKD 322
T N + + R+ IG+G+ F++ + L+ AS P + + L
Sbjct: 318 DPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDG 377
Query: 323 LFTELQKKIYVIEGTSKQDLTSFNMELSSSGISAD-LSRGHAVVGAVGAKDWAGGFLDLK 381
L ++L+ I +EGT L + +L+ G SA L ++GAVGA DW+GG L
Sbjct: 378 LLSKLRYNIISMEGTVGDAL---HYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYD 434
Query: 382 ADLQDDTFIGNEPLTPE----VRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQ 437
+ F+ + YLGY V L S +A GAPRY+H G V F+
Sbjct: 435 TRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIA-GAPRYKHHGAV--FE 491
Query: 438 EPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRVFIY 497
+ G S + + G Q+GSYFG ELC VD+D DG T+ LL+ AP ++ GRV++Y
Sbjct: 492 LQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVY 551
Query: 498 QRRQL--GFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGA----- 550
+ + F L G PG+ RFG A+ A+ D++ D L DVA+GAPLE GA
Sbjct: 552 RLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGAS 611
Query: 551 ---VYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQM 607
VYI+NG GLS PSQRI + V G+Q+FG S+ G D+ GDGLAD+ VG Q
Sbjct: 612 FGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQA 671
Query: 608 IVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQ-GR 666
+V SRPVV + M+F+P+ +P+ VN+ +CF+I S+ + G
Sbjct: 672 VVFRSRPVVRLKVSMAFTPSALPI-----------GFNGVVNVRLCFEISSVTTASESGL 720
Query: 667 LVANLTYTLQLDGHRTRRRGLFPGGRHELR-RNIAVTTSMSCTDFSF---HFPVCVQDLI 722
A L +TL +D + RRR R L + S C D +C +D
Sbjct: 721 REALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCF 780
Query: 723 SPINVSLNFSLWEEEGTPRDQRAQGKDIPPIL-RPSLHSETWEIPFEKNCGEDKKCEANL 781
S +V +++ L EG Q PIL R + +++P+EK C C A L
Sbjct: 781 SNASVKVSYQLQTPEG-------QTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAEL 833
Query: 782 RVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQI 841
+++ + + L + L++ ++L+N ED+Y + L++P L ++ M KP S
Sbjct: 834 QLA-TTVSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKR--MQKPPSP- 889
Query: 842 PVSCEELPEESRLLSRALSCNVSSPIFK---AGHSVALQMMFNTLVNSSWGDSVELHANV 898
+ C++ + +L ++C + P+ K A SV Q+ N N + ++ V
Sbjct: 890 NIQCDDPQPVASVL--IMNCRIGHPVLKRSSAHVSVVWQLEENAFPNR----TADITVTV 943
Query: 899 TCNNEDSDLLEDNSATT----IIPILYPINILIQDQEDSTLY---VSFTPKGPKIHQVKH 951
T +NE L + + +L +I+ + + F G + ++
Sbjct: 944 TNSNERRSLANETHTLQFRHGFVAVLSKPSIMYVNTGQGLSHHKEFLFHVHGENLFGAEY 1003
Query: 952 MYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAE 1011
Q+ + + L+ V ++ WS + C Y ++ + +
Sbjct: 1004 QLQICVPTKLRG-----LQVVAVKKLTRTQASTVCTWSQER----ACAYSSVQHVEEWHS 1054
Query: 1012 PCLPGALFRCPVVFRQEI-------LVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKH 1064
A + V EI L++ + L+++GE ISFN S +
Sbjct: 1055 VSCVIASDKENVTVAAEISWDHSEELLKDVTELQILGE--------------ISFNKSLY 1100
Query: 1065 FHLYGSNASLAQVVMKVDVVYEKQMLY----LYVLSGIGGLLLLLLIFIVLYKVGFFKRN 1120
L N K+ VV+ K Y + + +GGLL+L++I ++L+K GFFKR
Sbjct: 1101 EGLNAENHR-----TKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRK 1155
Query: 1121 LKE 1123
++
Sbjct: 1156 YQQ 1158
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 333 bits (853), Expect = 7e-91
Identities = 327/1193 (27%), Positives = 543/1193 (45%), Gaps = 147/1193 (12%)
Query: 25 SYNLDVRGARSFSPPRAGRHFGYRVLQV----GNGVIVGAPGEG---NSTGSLYQC--QS 75
+YN+ + A+ FS P + FGY V Q GN ++VG+P G N G +Y+C
Sbjct: 29 AYNVGLPEAKIFSGP-SSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKCPVDL 87
Query: 76 GTGHCLPVTLRGSNY--------TSKYLGMTLATDPTDGSILACDPGLSRTCDQNTYLSG 127
T C + L+ S T+ LG+ L + G L C P ++ C Y +G
Sbjct: 88 STATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQYYTTG 147
Query: 128 LCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLS 187
+C + Q P Q C +D+V + D S S+ P + + +F++ ++ L
Sbjct: 148 VCSDISPDFQ-LSASFSPATQPC-PSLIDVVVVCDESNSIYP--WDAVKNFLEKFVQGLD 203
Query: 188 --NTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHV-KHMLLLTNTFGAINYVATEV 244
T Q +Q++ + + F+ + Y +++ ++ LTNTFGAI Y
Sbjct: 204 IGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYA 263
Query: 245 FREELGARPDATKVLIIITDGEATDSGNIDAAKD------IIRYIIGIGKHFQ-----TK 293
+ G R ATKV++++TDGE+ D + A D I+R+ I + + TK
Sbjct: 264 YSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTK 323
Query: 294 ESQETLHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSG 353
+ + AS P + + L + L ++I+ IEGT Q +F ME+S G
Sbjct: 324 NLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTV-QGGDNFQMEMSQVG 382
Query: 354 ISADLSRGHAVV--GAVGAKDWAGGFLDLKAD----LQDDTFIGNEPLTPEVRAGYLGYT 407
SAD S + ++ GAVGA W+G + + F ++ L + YLGY+
Sbjct: 383 FSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAF--DQILQDRNHSSYLGYS 440
Query: 408 VTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGV 467
V + + + T +A GAPR + G+++L+ + G + + +Q G QIGSYFG LC V
Sbjct: 441 VAAISTGESTHFVA-GAPRANYTGQIVLYSVNENG-NITVIQAHRGDQIGSYFGSVLCSV 498
Query: 468 DVDQDGETELLLIGAPLFYGE--QRGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAI 525
DVD+D T++LL+GAP++ + + GRV+++ ++ + L+G G RFG AI
Sbjct: 499 DVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQFLEGPEGIENTRFGSAI 558
Query: 526 TALTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPSQRIEGTQ--VLSGIQWF 581
AL+DIN DG DV VG+PLE Q GAVYI+NG G + + SQ+I G+ S +Q+F
Sbjct: 559 AALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYF 618
Query: 582 GRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTS 641
GRS+ G DL GD + DV++GA Q++ L S+ + D+ SF+P +I +
Sbjct: 619 GRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTPEKI---------TLV 669
Query: 642 NKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTR--RRGLFPGGRHE-LRRN 698
NK + + + +CF K + ++ TL DG +R RGLF L++N
Sbjct: 670 NKNAQ-IILKLCFSAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGLFKENNERCLQKN 728
Query: 699 IAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSL 758
+ V + SC + + D+++ +++ ++ SL E GT P + S
Sbjct: 729 MVVNQAQSCPEHIIYIQE-PSDVVNSLDLRVDISL-ENPGTS----------PALEAYSE 776
Query: 759 HSETWEIPFEKNCGEDKKCEAN--LRVSFSPARSRALRLTAFAS--LSVELSLSNLEEDA 814
++ + IPF K+CGED C ++ L V PA + + + L+ ++L N E A
Sbjct: 777 TAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSVTLKNKRESA 836
Query: 815 YWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSV 874
Y + + F L F +PV E+ + ++++C+V P K V
Sbjct: 837 YNTGIVVDFSENLFFASF-------SLPVDGTEVTCQVAASQKSVACDVGYPALKREQQV 889
Query: 875 ALQMMFN-TLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPILYPINI-------- 925
+ F+ L N S+ A E+ DN IP+LY I
Sbjct: 890 TFTINFDFNLQNLQNQASLSFQALSESQEENK---ADNLVNLKIPLLYDAEIHLTRSTNI 946
Query: 926 ----LIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSE 981
+ D ++ SF GPK ++ +++ ++ T+ ++ +PQ E
Sbjct: 947 NFYEISSDGNVPSIVHSFEDVGPKF-----IFSLKVTTGSVPVSMATV--IIHIPQYTKE 999
Query: 982 -GPITHQWSVQMEP--PVPC---------------------HYEDLERLPDAAEPCLPGA 1017
P+ + VQ + + C ++ + L C
Sbjct: 1000 KNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVT 1059
Query: 1018 LFRCPVVFRQEILVQVIGTLELVGEIEASSMF---SLCSSLSISFNSSKHFHLYGSNASL 1074
+ V + E V V T + ASS F L ++ I+ + + + + + ++
Sbjct: 1060 CWLKDVHMKGEYFVNV--TTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYVIEDNTVTI 1117
Query: 1075 AQVVMKVDVVYEKQMLYLYVLSG--IGGLLLLLLIFIVLYKVGFFKRNLKEKM 1125
++MK D EK + V+ G I G+LLLL + +L+K+GFFKR EKM
Sbjct: 1118 PLMIMKPD---EKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFKRKY-EKM 1166
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 213 bits (542), Expect = 9e-55
Identities = 188/620 (30%), Positives = 305/620 (49%), Gaps = 66/620 (10%)
Query: 352 SGISADLSRGHAVVGAVGAKDWAGGFLDLKADLQDDTFIG-NEPLTPEVRAGYLGYTVTW 410
+GI+ + V+GA G+ WAG L +L D+T++ N+ + R YLGY VT
Sbjct: 196 AGIAGFFTEELVVMGAPGSFYWAGTIKVL--NLTDNTYLKLNDEVIMNRRYTYLGYAVTA 253
Query: 411 LP-SRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDV 469
S T + GAP+ + +G+V +F+ + G ++ G ++GSYFG LC VD+
Sbjct: 254 GHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDL 313
Query: 470 DQDGETELLLIGAPLFYGEQRGGRVFIYQRRQLG-FEEVSELQGDPGYPLGRFGEAITAL 528
+ DG ++LL +GAP+F + G+V +Y R G EE L GD Y FGE+I +L
Sbjct: 314 NGDGLSDLL-VGAPMFSEIRDEGQVTVYINRGNGALEEQLALTGDGAYN-AHFGESIASL 371
Query: 529 TDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIH 586
D++ DG DVA+GAP E+ GAVYI++G GG+ PQ S ++ G ++ ++ FG+SI
Sbjct: 372 DDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSIS 431
Query: 587 GVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKM 644
G D++G+G DV VGA +++L +RPV+ V + F P I + +C +
Sbjct: 432 GGIDMDGNGYPDVTVGAFMSDSVVLLRARPVI-TVDVSIFLPGSINITAPQC--HDGQQP 488
Query: 645 KEGVNITICFQIKSLIPQFQGRLV---ANLTYTLQLDGHRTRRRGLFP--------GGRH 693
+N+T CF F G+ V L Y L D + + +G P
Sbjct: 489 VNCLNVTTCF-------SFHGKHVPGEIGLNYVLMADVAK-KEKGQMPRVYFVLLGETMG 540
Query: 694 ELRRNIAVT-TSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAQGKDIPP 752
++ + +T +C + H VQD+ISPI +SL E T ++R ++PP
Sbjct: 541 QVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSL-SEHVTGEEER----ELPP 595
Query: 753 ILRPSLH-------SETWEIPFEKN-----CGEDKKCEANLRVSFSPARSRALRLTAFAS 800
L P L ++ + FE+N C D + + L +S ++ L L A +
Sbjct: 596 -LTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKN 654
Query: 801 LSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALS 860
+S+ +S+SNL +DAY + + L F + M + ++ +SCE L S L
Sbjct: 655 ISLNISISNLGDDAYDANVSFNVSRELFF--INMWQ-KEEMGISCELLE------SDFLK 705
Query: 861 CNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC---NNEDSDLLEDNSATTII 917
C+V P ++ ++F+T S G+ L VT N E S+ L DN+ ++
Sbjct: 706 CSVGFPFMRSKSKYEFSVIFDTSHLS--GEEEVLSFIVTAQSGNTERSESLHDNTLVLMV 763
Query: 918 PILYPINILIQDQEDSTLYV 937
P+++ ++ I T +V
Sbjct: 764 PLMHEVDTSITGIMSPTSFV 783
Score = 36.6 bits (83), Expect = 0.14
Identities = 15/37 (40%), Positives = 28/37 (75%)
Query: 1091 YLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEA 1127
++ +S + G+L+ LL+ ++L+K+GFF+R KE +EA
Sbjct: 981 WIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEA 1017
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 195 bits (495), Expect = 2e-49
Identities = 228/875 (26%), Positives = 393/875 (44%), Gaps = 101/875 (11%)
Query: 322 DLFTELQKKIYVIEGTSKQDLTSF---NMELSSSGISADLSRGHAVVGAVGAKDWAGGFL 378
DL TEL K+I QD N +GIS+ ++ V+GA G+ W G
Sbjct: 171 DLRTELSKRI----APCYQDYVKKFGENFASCQAGISSFYTKDLIVMGAPGSSYWTGSLF 226
Query: 379 DLKADLQD-DTFIGNEPLTPEVRAG-YLGYTVTWLPSR-QKTSLLASGAPRYQHMGRVLL 435
F+ + +V+ G YLGY+V R Q T+ + GAP+++ +G+ +
Sbjct: 227 VYNITTNKYKAFLDKQN---QVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYI 283
Query: 436 FQEPQGGGHWSQVQTIH---GTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGG 492
F + ++ +H G ++GSYFG +C VD++ DG ++LL +GAP+ + G
Sbjct: 284 FSIDE-----KELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLL-VGAPMQSTIREEG 337
Query: 493 RVFIYQRRQLGF---EEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE-- 547
RVF+Y G + L G Y RFGE+I L DI+ DG DVA+GAP E+
Sbjct: 338 RVFVYINSGSGAVMNAMETNLVGSDKYA-ARFGESIVNLGDIDNDGFEDVAIGAPQEDDL 396
Query: 548 QGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGA--ES 605
QGA+YI+NGR G+S SQRIEG Q+ + FG+SI G D + +G DVAVGA
Sbjct: 397 QGAIYIYNGRADGISSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSD 456
Query: 606 QMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQG 665
++L +RPVV + +S P + + +C + + +++T+CF K + G
Sbjct: 457 SAVLLRTRPVVIVDASLSH-PESVNRTKFDCVENGWPSVC--IDLTLCFSYKG--KEVPG 511
Query: 666 RLVANLTYTLQLDGHRTRR---RGLFP--GGRHELRRNIAVTT-SMSCTDFSFHFPVCVQ 719
+V L Y + LD +R R F G + +I V++ +C V+
Sbjct: 512 YIV--LFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVR 569
Query: 720 DLISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWE--IPFEKNCGEDKKC 777
D+++PI + + L + R + + PIL+ + + I F + C + C
Sbjct: 570 DILTPIQIEAAYHLGPHVISKRSTE-EFPPLQPILQQKKEKDIMKKTINFARFCAHEN-C 627
Query: 778 EANLRVS-----FSPARSRA-LRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRK 831
A+L+VS P ++ L + + +L + +SL N +DAY L + P GL F K
Sbjct: 628 SADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIK 687
Query: 832 VEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDS 891
+ L+ ++CE + + S ++ L C++ + + + + S +
Sbjct: 688 ILELEEKQ---INCE-VTDNSGVVQ--LDCSIGYIYVDHLSRIDISFLLDVSSLSRAEED 741
Query: 892 VELHANVTCNNEDS-DLLEDNSATTIIPILYPINILIQDQEDST--LYVSFTPKGPKIHQ 948
+ + + TC NE+ D L+ + T IP+ Y + + + + T +Y S P+
Sbjct: 742 LSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETCM 801
Query: 949 VKHMYQVRIQPSIHDHNIPTLEAVVGVPQP--PSEGPITHQWSVQMEPPVPCHYED---- 1002
V+ M + + P + + VP P + + VQ CH+E+
Sbjct: 802 VEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTG-ECHFENYQRV 860
Query: 1003 --LERLPDAAEPCLPGALFRCPVVFRQEILVQV----IGTLELVGEIEASSMFSLC---- 1052
LE+ A + F R ++ + L G++E+ S+
Sbjct: 861 CALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLE 920
Query: 1053 ---SSLSISFNSSKHFHLYGS--------------NASLAQVVMKVDVVYEKQMLYLYVL 1095
S L + S+ F + + + ++A V+++ + +++ Y ++
Sbjct: 921 GRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVAHVLLE-GLHHQRPKRYFTIV 979
Query: 1096 ----SGIGGLLLLLLIFIVLYKVGFFKRNLKEKME 1126
S + GL++LLLI V++K GFFKR K ++
Sbjct: 980 IISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQ 1014
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 173 bits (439), Expect = 8e-43
Identities = 157/558 (28%), Positives = 252/558 (45%), Gaps = 61/558 (10%)
Query: 353 GISADLSRGHAVVGAVGAKDWAGGFLDLKA---DLQDDTFIGNEPLTPEVRAG-YLGYT- 407
G S ++ GA GA +W G ++ DL + ++ PE + Y+GYT
Sbjct: 200 GTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSY-----KDPEDQGNLYIGYTM 254
Query: 408 -VTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCG 466
V K + +GAPR++HMG V L + + GG + Q + G+Q+G+YFG +
Sbjct: 255 QVGSFILHPKNITIVTGAPRHRHMGAVFLLSQ-EAGGDLRRRQVLEGSQVGAYFGSAIAL 313
Query: 467 VDVDQDGETELLLIGAPLFYG--EQRGGRVFIYQRRQLGFEEVSE----LQGDPGYPLGR 520
D++ DG +LL +GAP ++ E+ GG ++++ Q G + L G G
Sbjct: 314 ADLNNDGWQDLL-VGAPYYFERKEEVGGAIYVFMN-QAGTSFPAHPSLLLHGPSG---SA 368
Query: 521 FGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQV-LSGIQ 579
FG ++ ++ DIN DG D+AVGAP E G VYI++ GL QP Q I G ++ L G+
Sbjct: 369 FGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLA 428
Query: 580 WFGRSIHGVKDLEGDGLADVAVGAESQMIV-LSSRPVVDMVTLMSFSPAEIPVHEVECSY 638
FG S+ G D++ + D+ VG+ S IV L +RPV+++V + P + C+
Sbjct: 429 TFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVH-KTLVPRPAVLDPALCTA 487
Query: 639 STSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRN 698
++ V + +CF R L YTL+ D R R F G +
Sbjct: 488 TSC------VQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFHG 541
Query: 699 IAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSL 758
M C ++D + PI +S+N+SL + D PIL +
Sbjct: 542 FFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQ 601
Query: 759 HSET-WEIPFEKNCGEDKKCEANL--RVSFSPARSRALRLTAFA----SLSVELSLSNLE 811
E E+ F+K CG D KCE+NL R +F + + L ++ L + ++++N
Sbjct: 602 ALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTR 661
Query: 812 ------EDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSS 865
EDA+ L L PP L V + P +C+ + + C + +
Sbjct: 662 TSERSGEDAHEALLTLVVPPALLLSSV-------RPPGACQ--------ANETIFCELGN 706
Query: 866 PIFKAGHSVALQMMFNTL 883
P FK + L + F +
Sbjct: 707 P-FKRNQRMELLIAFEVI 723
Score = 32.3 bits (72), Expect = 2.7
Identities = 16/30 (53%), Positives = 23/30 (76%)
Query: 1090 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1119
L+L +++ GLLLL LI ++L+K GFFKR
Sbjct: 992 LWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 173 bits (439), Expect = 8e-43
Identities = 157/558 (28%), Positives = 252/558 (45%), Gaps = 61/558 (10%)
Query: 353 GISADLSRGHAVVGAVGAKDWAGGFLDLKA---DLQDDTFIGNEPLTPEVRAG-YLGYT- 407
G S ++ GA GA +W G ++ DL + ++ PE + Y+GYT
Sbjct: 200 GTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSY-----KDPEDQGNLYIGYTM 254
Query: 408 -VTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCG 466
V K + +GAPR++HMG V L + + GG + Q + G+Q+G+YFG +
Sbjct: 255 QVGSFILHPKNITIVTGAPRHRHMGAVFLLSQ-EAGGDLRRRQVLEGSQVGAYFGSAIAL 313
Query: 467 VDVDQDGETELLLIGAPLFYG--EQRGGRVFIYQRRQLGFEEVSE----LQGDPGYPLGR 520
D++ DG +LL +GAP ++ E+ GG ++++ Q G + L G G
Sbjct: 314 ADLNNDGWQDLL-VGAPYYFERKEEVGGAIYVFMN-QAGTSFPAHPSLLLHGPSG---SA 368
Query: 521 FGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQV-LSGIQ 579
FG ++ ++ DIN DG D+AVGAP E G VYI++ GL QP Q I G ++ L G+
Sbjct: 369 FGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLA 428
Query: 580 WFGRSIHGVKDLEGDGLADVAVGAESQMIV-LSSRPVVDMVTLMSFSPAEIPVHEVECSY 638
FG S+ G D++ + D+ VG+ S IV L +RPV+++V + P + C+
Sbjct: 429 TFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVH-KTLVPRPAVLDPALCTA 487
Query: 639 STSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRN 698
++ V + +CF R L YTL+ D R R F G +
Sbjct: 488 TSC------VQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFHG 541
Query: 699 IAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSL 758
M C ++D + PI +S+N+SL + D PIL +
Sbjct: 542 FFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQ 601
Query: 759 HSET-WEIPFEKNCGEDKKCEANL--RVSFSPARSRALRLTAFA----SLSVELSLSNLE 811
E E+ F+K CG D KCE+NL R +F + + L ++ L + ++++N
Sbjct: 602 ALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTR 661
Query: 812 ------EDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSS 865
EDA+ L L PP L V + P +C+ + + C + +
Sbjct: 662 TSERSGEDAHEALLTLVVPPALLLSSV-------RPPGACQ--------ANETIFCELGN 706
Query: 866 PIFKAGHSVALQMMFNTL 883
P FK + L + F +
Sbjct: 707 P-FKRNQRMELLIAFEVI 723
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 162 bits (409), Expect = 2e-39
Identities = 230/914 (25%), Positives = 376/914 (41%), Gaps = 167/914 (18%)
Query: 362 HAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRA----------GYLGYTVT-- 409
+ + GA G +W G D D + + L P R YLG+++
Sbjct: 211 YLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSG 270
Query: 410 -WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVD 468
L ++ S +A GAPR H G V++ ++ +V + G ++ S FG L D
Sbjct: 271 KGLVRAEELSFVA-GAPRANHKGAVVILRKDSASRLVPEVM-LSGERLTSGFGYSLAVAD 328
Query: 469 VDQDGETELLLIGAPLFYGEQR--GGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAIT 526
++ DG +L+ +GAP F+ Q GG V++Y + + +S L+ G P FG ++
Sbjct: 329 LNSDGWPDLI-VGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC-GSPDSMFGISLA 386
Query: 527 ALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIH 586
L D+N DG D+AVGAP + G V+I++G G+ +PSQ +EG V GI+ FG S+
Sbjct: 387 VLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSFGYSLS 444
Query: 587 GVKDLEGDGLADVAVGAESQMIVL-SSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMK 645
G D++G+ D+ VG+ + VL +RP++ + +S +P I + + C+ S
Sbjct: 445 GSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHS---- 500
Query: 646 EGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSM 705
V++ +CF + +P VA L Y L D R R RG P L RN+
Sbjct: 501 VCVDLRVCFSYIA-VPSSYSPTVA-LDYVLDADTDR-RLRGQVPRVTF-LSRNLEEPKHQ 556
Query: 706 S-------------CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQR-AQGKDIP 751
+ C D F V+D + I V+L++SL TPR +R A G+ +P
Sbjct: 557 ASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ----TPRLRRQAPGQGLP 612
Query: 752 PILRPSLHS-----ETWEIPFEKN-CGEDKKCEANLRV------------SFSPARSRAL 793
P+ P L++ + EI F K CGEDK C++NL++ F P
Sbjct: 613 PVA-PILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVD 671
Query: 794 RLTAFASLS------VELSLSNLE----------EDAYWVQLDLHFPPGLSFRKVEML-- 835
TA +LS +EL ++NL +DA+ QL + P L + V L
Sbjct: 672 GTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDP 731
Query: 836 -----------------------KPHSQIP---------VSCEELPEESRLLSRALSCN- 862
K +Q+ +S E E LL +S
Sbjct: 732 AEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQE 791
Query: 863 -----------VSSPIFKAGHSVALQMMFNTLVNSSWGDSVE------LHANVTCNNEDS 905
+ P+ AG ++ Q+ F+ +V E + VT +N+
Sbjct: 792 LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQ 851
Query: 906 DLLEDNSATTIIP----------ILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQV 955
L SA I +LYP+ + ++ + +P+ +H
Sbjct: 852 SLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILH-------- 903
Query: 956 RIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLP 1015
+ D LE P + P Q PV + D A
Sbjct: 904 -LDVDSRDRRRRELEP------PEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTAN 956
Query: 1016 GALFRCPVV-FRQEILVQVIGTL---ELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSN 1071
+F CP+ F + ++ V G L + E A + +I+ SS +
Sbjct: 957 CVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDA 1016
Query: 1072 ASLAQVVMKVD---VVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAG 1128
+++ V++ +D VV E ++ +L+ + GLL+L L+ ++L+K+GFFKR +
Sbjct: 1017 STVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVP 1076
Query: 1129 RGVPNGIPAEDSEQ 1142
+ IP ED +Q
Sbjct: 1077 QYHAVKIPREDRQQ 1090
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 159 bits (402), Expect = 1e-38
Identities = 234/919 (25%), Positives = 379/919 (41%), Gaps = 173/919 (18%)
Query: 362 HAVVGAVGAKDWAG---------GFLDLKADLQDDTF-IGNEP-----LTPEVRAGYLGY 406
+ + GA G +W G G DL A L D + G E L P Y G+
Sbjct: 114 YLLFGAPGTYNWKGTARVELCAQGSADL-AHLDDGPYEAGGEKEQDPRLIPVPANSYFGF 172
Query: 407 TVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGE 463
++ L ++ S +A GAPR H G V++ ++ +V + G ++ S FG
Sbjct: 173 SIDSGKGLVRAEELSFVA-GAPRANHKGAVVILRKDSASRLVPEVM-LSGERLTSGFGYS 230
Query: 464 LCGVDVDQDGETELLLIGAPLFYGEQR--GGRVFIYQRRQLGFEEVSELQGDPGYPLGRF 521
L D++ DG +L+ +GAP F+ Q GG V++Y + + +S L+ G P F
Sbjct: 231 LAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC-GSPDSMF 288
Query: 522 GEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWF 581
G ++ L D+N DG D+AVGAP + G V+I++G G+ +PSQ +EG V GI+ F
Sbjct: 289 GISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSF 346
Query: 582 GRSIHGVKDLEGDGLADVAVGAESQMIVL-SSRPVVDMVTLMSFSPAEIPVHEVECSYST 640
G S+ G D++G+ D+ VG+ + VL +RP++ + +S +P I + + C+
Sbjct: 347 GYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGH 406
Query: 641 SNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIA 700
S V++ +CF + +P VA L Y L D R R RG P L RN+
Sbjct: 407 S----VCVDLRVCFSYIA-VPSSYSPTVA-LDYVLDADTDR-RLRGQVPRVTF-LSRNLE 458
Query: 701 VTTSMS-------------CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQR-AQ 746
+ C D F V+D + I V+L++SL TPR +R A
Sbjct: 459 EPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ----TPRLRRQAP 514
Query: 747 GKDIPPILRPSLHS-----ETWEIPFEKN-CGEDKKCEANLRV------------SFSPA 788
G+ +PP+ P L++ + EI F K CGEDK C++NL++ F P
Sbjct: 515 GQGLPPVA-PILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPL 573
Query: 789 RSRALRLTAFASLS------VELSLSNLE----------EDAYWVQLDLHFPPGLSFRKV 832
TA +LS +EL ++NL +DA+ QL + P L + V
Sbjct: 574 PMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGV 633
Query: 833 EML-------------------------KPHSQIP---------VSCEELPEESRLLSRA 858
L K +Q+ +S E E LL
Sbjct: 634 RALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLAT 693
Query: 859 LSCN------------VSSPIFKAGHSVALQMMFNTLVNSSWGDSVE------LHANVTC 900
+S + P+ AG ++ Q+ F+ +V E + VT
Sbjct: 694 ISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTV 753
Query: 901 NNEDSDLLEDNSATTIIP----------ILYPINILIQDQEDSTLYVSFTPKGPKIHQVK 950
+N+ L SA I +LYP+ + ++ + +P+ +H
Sbjct: 754 SNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILH--- 810
Query: 951 HMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAA 1010
+ D LE P + P Q PV + D A
Sbjct: 811 ------LDVDSRDRRRRELEP------PEQQEPGERQEPSMSWWPVSSAEKKKNITLDCA 858
Query: 1011 EPCLPGALFRCPVV-FRQEILVQVIGTL---ELVGEIEASSMFSLCSSLSISFNSSKHFH 1066
+F CP+ F + ++ V G L + E A + +I+ SS
Sbjct: 859 RGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNL 918
Query: 1067 LYGSNASLAQVVMKVD---VVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKE 1123
+ +++ V++ +D VV E ++ +L+ + GLL+L L+ ++L+K+GFFKR
Sbjct: 919 MLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHP 978
Query: 1124 KMEAGRGVPNGIPAEDSEQ 1142
+ + IP ED +Q
Sbjct: 979 EATVPQYHAVKIPREDRQQ 997
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 159 bits (402), Expect = 1e-38
Identities = 234/919 (25%), Positives = 379/919 (41%), Gaps = 173/919 (18%)
Query: 362 HAVVGAVGAKDWAG---------GFLDLKADLQDDTF-IGNEP-----LTPEVRAGYLGY 406
+ + GA G +W G G DL A L D + G E L P Y G+
Sbjct: 211 YLLFGAPGTYNWKGTARVELCAQGSADL-AHLDDGPYEAGGEKEQDPRLIPVPANSYFGF 269
Query: 407 TVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGE 463
++ L ++ S +A GAPR H G V++ ++ +V + G ++ S FG
Sbjct: 270 SIDSGKGLVRAEELSFVA-GAPRANHKGAVVILRKDSASRLVPEVM-LSGERLTSGFGYS 327
Query: 464 LCGVDVDQDGETELLLIGAPLFYGEQR--GGRVFIYQRRQLGFEEVSELQGDPGYPLGRF 521
L D++ DG +L+ +GAP F+ Q GG V++Y + + +S L+ G P F
Sbjct: 328 LAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC-GSPDSMF 385
Query: 522 GEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWF 581
G ++ L D+N DG D+AVGAP + G V+I++G G+ +PSQ +EG V GI+ F
Sbjct: 386 GISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSF 443
Query: 582 GRSIHGVKDLEGDGLADVAVGAESQMIVL-SSRPVVDMVTLMSFSPAEIPVHEVECSYST 640
G S+ G D++G+ D+ VG+ + VL +RP++ + +S +P I + + C+
Sbjct: 444 GYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGH 503
Query: 641 SNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIA 700
S V++ +CF + +P VA L Y L D R R RG P L RN+
Sbjct: 504 S----VCVDLRVCFSYIA-VPSSYSPTVA-LDYVLDADTDR-RLRGQVPRVTF-LSRNLE 555
Query: 701 VTTSMS-------------CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQR-AQ 746
+ C D F V+D + I V+L++SL TPR +R A
Sbjct: 556 EPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ----TPRLRRQAP 611
Query: 747 GKDIPPILRPSLHS-----ETWEIPFEKN-CGEDKKCEANLRV------------SFSPA 788
G+ +PP+ P L++ + EI F K CGEDK C++NL++ F P
Sbjct: 612 GQGLPPVA-PILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPL 670
Query: 789 RSRALRLTAFASLS------VELSLSNLE----------EDAYWVQLDLHFPPGLSFRKV 832
TA +LS +EL ++NL +DA+ QL + P L + V
Sbjct: 671 PMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGV 730
Query: 833 EML-------------------------KPHSQIP---------VSCEELPEESRLLSRA 858
L K +Q+ +S E E LL
Sbjct: 731 RALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLAT 790
Query: 859 LSCN------------VSSPIFKAGHSVALQMMFNTLVNSSWGDSVE------LHANVTC 900
+S + P+ AG ++ Q+ F+ +V E + VT
Sbjct: 791 ISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTV 850
Query: 901 NNEDSDLLEDNSATTIIP----------ILYPINILIQDQEDSTLYVSFTPKGPKIHQVK 950
+N+ L SA I +LYP+ + ++ + +P+ +H
Sbjct: 851 SNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILH--- 907
Query: 951 HMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAA 1010
+ D LE P + P Q PV + D A
Sbjct: 908 ------LDVDSRDRRRRELEP------PEQQEPGERQEPSMSWWPVSSAEKKKNITLDCA 955
Query: 1011 EPCLPGALFRCPVV-FRQEILVQVIGTL---ELVGEIEASSMFSLCSSLSISFNSSKHFH 1066
+F CP+ F + ++ V G L + E A + +I+ SS
Sbjct: 956 RGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNL 1015
Query: 1067 LYGSNASLAQVVMKVD---VVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKE 1123
+ +++ V++ +D VV E ++ +L+ + GLL+L L+ ++L+K+GFFKR
Sbjct: 1016 MLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHP 1075
Query: 1124 KMEAGRGVPNGIPAEDSEQ 1142
+ + IP ED +Q
Sbjct: 1076 EATVPQYHAVKIPREDRQQ 1094
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 152 bits (385), Expect = 1e-36
Identities = 209/856 (24%), Positives = 357/856 (41%), Gaps = 120/856 (14%)
Query: 353 GISADLSR-GHAVVGAVGAKDWAGGFLDLKADLQDDTF--------IGNEPLTPEVRA-- 401
G SA+ ++ G V+G G+ W G L + +++ + + T + +
Sbjct: 208 GFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPEYLINLVQGQLQTRQASSIY 267
Query: 402 --GYLGYTVTWLP-SRQKTSLLASGAPRYQ-HMGRVLLFQEPQGGGHWSQVQTIHGTQIG 457
YLGY+V S T +G P+ G V + G + G Q+
Sbjct: 268 DDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTILN----GSDIRSLYNFSGEQMA 323
Query: 458 SYFGGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQRRQLGFEEVSELQ 511
SYFG + DV+ DG +LL +GAPL Q GRV++Y + G E L
Sbjct: 324 SYFGYAVAATDVNGDGLDDLL-VGAPLLMDRTPDGRPQEVGRVYVYLQHPAGIEPTPTLT 382
Query: 512 GDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHGGLSPQPSQR 568
GRFG ++T L D++ DG DVA+GAP +QG V++F G GGL +PSQ
Sbjct: 383 LTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGGLGSKPSQV 442
Query: 569 IEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTLMSFS 625
++ S +FG ++ G +DL+G+G D+ VG+ + +V RP+V ++
Sbjct: 443 LQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIVSASASLTIF 502
Query: 626 PAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVAN---LTYTLQLDGHRT 682
PA E C S +N++ C G+ VA+ T LQLD +
Sbjct: 503 PAMFNPEERSC--SLEGNPVACINLSFCLNA-------SGKHVADSIGFTVELQLDWQKQ 553
Query: 683 R---RRGLFPGGRH-ELRRNIAVTTSM--SCTDFSFHF--PVCVQDLISPINVSLNFSLW 734
+ RR LF R L + + + C + + +D +SPI+++LNFSL
Sbjct: 554 KGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSL- 612
Query: 735 EEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEK-----NCGEDKKCEANLRVSFSPAR 789
+ P D LRP+LH ++ +K +CGED C +L++ +
Sbjct: 613 -DPQAPVDSHG--------LRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEVFGEQ 663
Query: 790 SRALRLTAFASLSVELSLSNL-EEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEEL 848
+ + L +L++ N+ E AY +L + PP + + + P + +SC+
Sbjct: 664 NH-VYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGL-VRHPGNFSSLSCDYF 721
Query: 849 PEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANV---TCNNEDS 905
SR L C++ +P+ KAG S+ + F +++ + NN S
Sbjct: 722 AVNQ---SRLLVCDLGNPM-KAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQS 777
Query: 906 DL------LEDNSATTIIPILYPINIL--IQDQEDSTLYVSFTPKGPKIHQV-------- 949
D+ +E + T+ + P +L + D GP +H V
Sbjct: 778 DVVSFRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGP 837
Query: 950 ----KHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLER 1005
+ + ++ ++ + + V G+ + PI + ++++P H++
Sbjct: 838 SSISQGVLELSCPQALEGQQLLYVTRVTGL-NCTTNHPINPK-GLELDPEGSLHHQQKRE 895
Query: 1006 LPDAAEPCLPGALFRCPVV--FRQE-----ILVQVIGTLELVGEIEASSM-------FSL 1051
P + + +CP FR + Q +L+L + A + FSL
Sbjct: 896 APSRSSASSGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQPFSL 955
Query: 1052 -CSSLSISFNSSKHF---HLYGSNASLAQVVM--KVDVVYEKQMLYLYVLSGIGGLLLLL 1105
C ++ + L +A V K + Y L++ +L+ + GLLLL
Sbjct: 956 QCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVP-LWIIILAILFGLLLLG 1014
Query: 1106 LIFIVLYKVGFFKRNL 1121
L+ +LYK+GFFKR+L
Sbjct: 1015 LLIYILYKLGFFKRSL 1030
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 141 bits (355), Expect = 4e-33
Identities = 158/599 (26%), Positives = 271/599 (45%), Gaps = 76/599 (12%)
Query: 352 SGISADLSR-GHAVVGAVGAKDWAG--------------GFLDLKADLQDDTFIGNEPLT 396
+G S D + G +VG G+ W G F D+ L + P +
Sbjct: 202 AGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPAS 261
Query: 397 PEVRAGYLGYTVTWLP-SRQKTSLLASGAPR-YQHMGRVLLFQEPQGGGHWSQVQTIHGT 454
+ YLGY+V + L +G PR Q+ G V + + +Q G
Sbjct: 262 YD--DSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTD----MTFIQNFTGE 315
Query: 455 QIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQ------RGGRVFIY-QRRQLGFEEV 507
Q+ SYFG + DV+ DG ++L +GAPLF + G++++Y Q L F +
Sbjct: 316 QMASYFGYTVVVSDVNSDGLDDVL-VGAPLFMEREFESNPREVGQIYLYLQVSSLLFRDP 374
Query: 508 SELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHGGLSPQ 564
L G + GRFG A+ L D+N DG D+A+G P +++G V I+NG GL+ +
Sbjct: 375 QILTGTETF--GRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTK 432
Query: 565 PSQRIEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTL 621
PSQ ++G + FG ++ G D++ + D+ VGA ++ V +RPVV +
Sbjct: 433 PSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQ 492
Query: 622 MSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVAN---LTYTLQLD 678
+ P I + C ++ + + CF ++ + G+ +AN L +QLD
Sbjct: 493 LLLHPMIINLENKTC------QVPDSMTSAACFSLR-VCASVTGQSIANTIVLMAEVQLD 545
Query: 679 GHRTR---RRGLFPGGRHELRRNIAVT----TSMSCTDFSFHF--PVCVQDLISPINVSL 729
+ + +R LF H+ R + S C DF + +D +SPIN+SL
Sbjct: 546 SLKQKGAIKRTLFL-DNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISL 604
Query: 730 NFSLWEEEGTPRDQRAQGKDIPPIL---RPSLHSETWEIPFEKNCGEDKKCEANLRVSFS 786
N+SL +E T + +G ++ PIL R ++ SE I + CGED C +L++S
Sbjct: 605 NYSL--DESTFK----EGLEVKPILNYYRENIVSEQAHILVD--CGEDNLCVPDLKLSAR 656
Query: 787 PARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCE 846
P + + + + L + ++ N E AY +L + P + +E + P+SCE
Sbjct: 657 PDKHQVI-IGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFR-PLSCE 714
Query: 847 ELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDS 905
E ++R + C++ +P+ +G + +L + F S+ + +N+D+
Sbjct: 715 YKMEN---VTRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDN 769
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor
[Homo sapiens]
Length = 1091
Score = 139 bits (349), Expect = 2e-32
Identities = 154/647 (23%), Positives = 278/647 (42%), Gaps = 112/647 (17%)
Query: 353 GISADLSRG--HAVVGAVGAKDWAGGFLDLKADLQDDTFIG-----------------NE 393
G++A ++ + V GA G +W G ++ + +++TF +E
Sbjct: 191 GVAATFTKDFHYIVFGAPGTYNWKG---IVRVEQKNNTFFDMNIFEDGPYEVGGETEHDE 247
Query: 394 PLTPEVRAGYLGYTVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQT 450
L P YLG+++ + S+ + + + SGAPR H G V+L + H
Sbjct: 248 SLVPVPANSYLGFSLDSGKGIVSKDEITFV-SGAPRANHSGAVVLLKRDMKSAHLLPEHI 306
Query: 451 IHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE--QRGGRVFIYQRRQLGFEEVS 508
G + S FG ++ VD+++DG +++ IGAP ++ + GG V++Y +Q + V
Sbjct: 307 FDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGRWNNVK 365
Query: 509 ELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQR 568
++ + G FG A+ + DIN DG D+AVGAP ++ G V+I++G G++ +P
Sbjct: 366 PIRLN-GTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKP--- 421
Query: 569 IEGTQVLSGIQ-WFGRSIHGVKDLEGDGLADVAVGAESQMI-VLSSRPVVDMVTLMSFSP 626
TQVL GI +FG SI G DL+ + DVAVG+ S + + SRPV+++ ++ +P
Sbjct: 422 ---TQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTP 478
Query: 627 AEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVAN----LTYTLQLDGHRT 682
I + + K G IC Q+KS N + TL+ + R
Sbjct: 479 NRIDLRQ---------KTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERR 529
Query: 683 ----------RRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFS 732
R +G P EL + C + + ++D + PI ++ +
Sbjct: 530 KSGLSSRVQFRNQGSEPKYTQEL--TLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVE 587
Query: 733 LWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIP------FEKNCGEDKKCEANLRVSF- 785
+ E R + +P +L P L+S+ + ++ CG+D C +NL++ +
Sbjct: 588 IQEP-----SSRRRVNSLPEVL-PILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYK 641
Query: 786 -------------------------SPARSRALRLTAFASLSVELSLSNLEEDAYWVQLD 820
+ AL +T S S + + +DA+ +L
Sbjct: 642 FCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLI 701
Query: 821 LHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMF 880
FP L++ L+ + +SC S+ C + +P FK +V ++
Sbjct: 702 ATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQ-----ADCELGNP-FKRNSNVTFYLVL 755
Query: 881 NTLVNSSWGDSVELHANV---TCNNEDSDLLEDNSATTIIPILYPIN 924
+T D+ +L N+ T +N+D+ A +I +L ++
Sbjct: 756 ST--TEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVS 800
Score = 30.8 bits (68), Expect = 7.9
Identities = 11/30 (36%), Positives = 23/30 (76%)
Query: 1091 YLYVLSGIGGLLLLLLIFIVLYKVGFFKRN 1120
++ +++ + G+L+L L+ +L+K GFFKR+
Sbjct: 1016 WIILVAILAGILMLALLVFILWKCGFFKRS 1045
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor
[Homo sapiens]
Length = 1073
Score = 139 bits (349), Expect = 2e-32
Identities = 154/647 (23%), Positives = 278/647 (42%), Gaps = 112/647 (17%)
Query: 353 GISADLSRG--HAVVGAVGAKDWAGGFLDLKADLQDDTFIG-----------------NE 393
G++A ++ + V GA G +W G ++ + +++TF +E
Sbjct: 191 GVAATFTKDFHYIVFGAPGTYNWKG---IVRVEQKNNTFFDMNIFEDGPYEVGGETEHDE 247
Query: 394 PLTPEVRAGYLGYTVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQT 450
L P YLG+++ + S+ + + + SGAPR H G V+L + H
Sbjct: 248 SLVPVPANSYLGFSLDSGKGIVSKDEITFV-SGAPRANHSGAVVLLKRDMKSAHLLPEHI 306
Query: 451 IHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE--QRGGRVFIYQRRQLGFEEVS 508
G + S FG ++ VD+++DG +++ IGAP ++ + GG V++Y +Q + V
Sbjct: 307 FDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGRWNNVK 365
Query: 509 ELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQR 568
++ + G FG A+ + DIN DG D+AVGAP ++ G V+I++G G++ +P
Sbjct: 366 PIRLN-GTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKP--- 421
Query: 569 IEGTQVLSGIQ-WFGRSIHGVKDLEGDGLADVAVGAESQMI-VLSSRPVVDMVTLMSFSP 626
TQVL GI +FG SI G DL+ + DVAVG+ S + + SRPV+++ ++ +P
Sbjct: 422 ---TQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTP 478
Query: 627 AEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVAN----LTYTLQLDGHRT 682
I + + K G IC Q+KS N + TL+ + R
Sbjct: 479 NRIDLRQ---------KTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERR 529
Query: 683 ----------RRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFS 732
R +G P EL + C + + ++D + PI ++ +
Sbjct: 530 KSGLSSRVQFRNQGSEPKYTQEL--TLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVE 587
Query: 733 LWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIP------FEKNCGEDKKCEANLRVSF- 785
+ E R + +P +L P L+S+ + ++ CG+D C +NL++ +
Sbjct: 588 IQEP-----SSRRRVNSLPEVL-PILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYK 641
Query: 786 -------------------------SPARSRALRLTAFASLSVELSLSNLEEDAYWVQLD 820
+ AL +T S S + + +DA+ +L
Sbjct: 642 FCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLI 701
Query: 821 LHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMF 880
FP L++ L+ + +SC S+ C + +P FK +V ++
Sbjct: 702 ATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQ-----ADCELGNP-FKRNSNVTFYLVL 755
Query: 881 NTLVNSSWGDSVELHANV---TCNNEDSDLLEDNSATTIIPILYPIN 924
+T D+ +L N+ T +N+D+ A +I +L ++
Sbjct: 756 ST--TEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVS 800
Score = 36.2 bits (82), Expect = 0.19
Identities = 14/37 (37%), Positives = 27/37 (72%)
Query: 1091 YLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEA 1127
++ +++ + G+L+L L+ +L+K GFFKRN K+ +A
Sbjct: 1016 WIILVAILAGILMLALLVFILWKCGFFKRNKKDHYDA 1052
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 138 bits (348), Expect = 3e-32
Identities = 206/828 (24%), Positives = 339/828 (40%), Gaps = 144/828 (17%)
Query: 397 PEVRAGYLGYTVTW--LPSRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGHWSQVQTIHG 453
PE GY GY+V T+ GAP + +G V + ++ ++ + G
Sbjct: 259 PEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDS-----YYQRLHRLRG 313
Query: 454 TQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRG-------GRVFIYQRRQ----L 502
Q+ SYFG + DV+ DG +LL +GAPL Y E R GRV+++ + + L
Sbjct: 314 EQMASYFGHSVAVTDVNGDGRHDLL-VGAPL-YMESRADRKLAEVGRVYLFLQPRGPHAL 371
Query: 503 GFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHG 559
G + L G Y GRFG AI L D++ DG D+AV AP +G V +F G+
Sbjct: 372 GAPSLL-LTGTQLY--GRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSE 428
Query: 560 GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVD 617
GL +PSQ ++ FG S+ G D++ +G D+ VGA +Q+ V ++PVV
Sbjct: 429 GLRSRPSQVLDSPFPTGSA--FGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVK 486
Query: 618 MVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKS-LIPQFQGRLVANLTYTLQ 676
+ + P + C + NI +C IPQ +L LQ
Sbjct: 487 ASVQLLVQDSLNPAVK-SCVLPQTKTPVSCFNIQMCVGATGHNIPQ-----KLSLNAELQ 540
Query: 677 LDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVC------------VQDLISP 724
LD + R+ G R L + T+++ H P+C +D +SP
Sbjct: 541 LDRQKPRQ-----GRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSP 595
Query: 725 INVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVS 784
I +SLN SL E G +L H + + +CGED C L+++
Sbjct: 596 IVLSLNVSLPPTEA--------GMAPAVVLHGDTHVQE-QTRIVLDCGEDDVCVPQLQLT 646
Query: 785 FSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVS 844
S S L + A L +++ +N E AY +L +H P G + + + +
Sbjct: 647 ASVTGS-PLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRA-LSNVEGFERLI 704
Query: 845 CEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNED 904
C + E +R + C + +P+ K + + M+ + G+SV + N
Sbjct: 705 CNQKKENE---TRVVLCELGNPM-KKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQ 760
Query: 905 SDLLEDNSATTIIPI-------------LYPINILIQDQEDSTLYVSFTPKGPKIHQVKH 951
+ NS ++ + +P ++++ +E S GPK V+H
Sbjct: 761 N----PNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPK---VEH 813
Query: 952 MYQV-------------------RIQPS--IHDHNIPTLEAVVGVPQPPSEGPITHQWSV 990
Y++ + QPS ++ +I + PQPP P+ W +
Sbjct: 814 TYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPP-VNPLKVDWGL 872
Query: 991 QMEPPVPCHYEDLER------LPDAAEP------------CLPGALFRC---PVVFRQEI 1029
+ P P H +R LP+ +P P + +C + Q
Sbjct: 873 PIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRA 932
Query: 1030 LVQVIGTLELVGEIEAS-SMFSLCSSLSISFNSSKH----FHLYGSNASLAQVVMKVDVV 1084
+V V+ L L + F L S + +S + L A + +++ +
Sbjct: 933 MVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLR--AL 990
Query: 1085 YEKQMLYLYVLSGI-GGLLLLLLIFIVLYKVGFFKRN---LKEKMEAG 1128
E+ + +VL G+ GGLLLL ++ + ++KVGFFKRN L+E E G
Sbjct: 991 EERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEG 1038
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 121 bits (304), Expect = 3e-27
Identities = 152/602 (25%), Positives = 254/602 (42%), Gaps = 64/602 (10%)
Query: 340 QDLTSFNMELSSSGISADLSRGHAVV-GAVGAKDWAGGFL-----DLKADLQDDTF---I 390
QD+ + G S D ++ V+ G G+ W G + ++ + + +
Sbjct: 129 QDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKY 188
Query: 391 GNEPLTPEVRA----GYLGYTVTWLP-SRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGH 444
N+ T +A YLGY+V + SG PR +G V ++ G +
Sbjct: 189 NNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYD----GKN 244
Query: 445 WSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQ 498
S + G Q+ +YFG + D++ D ++ IGAPLF Q G+V +
Sbjct: 245 MSSLYNFTGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL 303
Query: 499 RRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFN 555
+R G + ++L G + RFG AI L D++ DG D+A+ AP +++G VYIFN
Sbjct: 304 QRASGDFQTTKLNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFN 361
Query: 556 GRHGGLSPQPSQRIEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSS 612
GR GL+ PSQ +EG + FG S+ G D++ +G D+ VGA + I+ +
Sbjct: 362 GRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRA 421
Query: 613 RPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI--KSLIPQFQGRLVAN 670
RPV+ + + P+ + CS + N+ C + K ++P+ V
Sbjct: 422 RPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL 481
Query: 671 LTYTLQLDGHRTRRRGLFPGGR---HELRRNIAVTTSMSCTDFSFHF--PVCVQDLISPI 725
L L+ G RR LF R H I+ M C + + +D ++PI
Sbjct: 482 LLDKLKQKG--AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPI 539
Query: 726 NVSLNFSLWEEEGTPRDQR--AQGKDIPPILR---PSLHSETWEIPFEKNCGEDKKCEAN 780
+ + + L D R A + PIL P+ S I + CGED C+
Sbjct: 540 TIFMEYRL--------DYRTAADTTGLQPILNQFTPANISRQAHILLD--CGEDNVCKPK 589
Query: 781 LRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQ 840
L VS + + + + L++ + N E AY +L + P F V + +
Sbjct: 590 LEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGV-VRNNEAL 647
Query: 841 IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC 900
+SC E +R + C++ +P+ KAG + + F+ S SV+ +
Sbjct: 648 ARLSCAFKTENQ---TRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQS 703
Query: 901 NN 902
+N
Sbjct: 704 SN 705
Score = 34.3 bits (77), Expect = 0.71
Identities = 13/30 (43%), Positives = 24/30 (80%)
Query: 1090 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1119
+++ +L+ + GLLLL ++ V+Y++GFFKR
Sbjct: 948 VWVIILAVLAGLLLLAVLVFVMYRMGFFKR 977
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 121 bits (304), Expect = 3e-27
Identities = 152/602 (25%), Positives = 254/602 (42%), Gaps = 64/602 (10%)
Query: 340 QDLTSFNMELSSSGISADLSRGHAVV-GAVGAKDWAGGFL-----DLKADLQDDTF---I 390
QD+ + G S D ++ V+ G G+ W G + ++ + + +
Sbjct: 175 QDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKY 234
Query: 391 GNEPLTPEVRA----GYLGYTVTWLP-SRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGH 444
N+ T +A YLGY+V + SG PR +G V ++ G +
Sbjct: 235 NNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYD----GKN 290
Query: 445 WSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQ 498
S + G Q+ +YFG + D++ D ++ IGAPLF Q G+V +
Sbjct: 291 MSSLYNFTGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL 349
Query: 499 RRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFN 555
+R G + ++L G + RFG AI L D++ DG D+A+ AP +++G VYIFN
Sbjct: 350 QRASGDFQTTKLNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFN 407
Query: 556 GRHGGLSPQPSQRIEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSS 612
GR GL+ PSQ +EG + FG S+ G D++ +G D+ VGA + I+ +
Sbjct: 408 GRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRA 467
Query: 613 RPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI--KSLIPQFQGRLVAN 670
RPV+ + + P+ + CS + N+ C + K ++P+ V
Sbjct: 468 RPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL 527
Query: 671 LTYTLQLDGHRTRRRGLFPGGR---HELRRNIAVTTSMSCTDFSFHF--PVCVQDLISPI 725
L L+ G RR LF R H I+ M C + + +D ++PI
Sbjct: 528 LLDKLKQKG--AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPI 585
Query: 726 NVSLNFSLWEEEGTPRDQR--AQGKDIPPILR---PSLHSETWEIPFEKNCGEDKKCEAN 780
+ + + L D R A + PIL P+ S I + CGED C+
Sbjct: 586 TIFMEYRL--------DYRTAADTTGLQPILNQFTPANISRQAHILLD--CGEDNVCKPK 635
Query: 781 LRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQ 840
L VS + + + + L++ + N E AY +L + P F V + +
Sbjct: 636 LEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGV-VRNNEAL 693
Query: 841 IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC 900
+SC E +R + C++ +P+ KAG + + F+ S SV+ +
Sbjct: 694 ARLSCAFKTENQ---TRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQS 749
Query: 901 NN 902
+N
Sbjct: 750 SN 751
Score = 34.3 bits (77), Expect = 0.71
Identities = 13/30 (43%), Positives = 24/30 (80%)
Query: 1090 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1119
+++ +L+ + GLLLL ++ V+Y++GFFKR
Sbjct: 994 VWVIILAVLAGLLLLAVLVFVMYRMGFFKR 1023
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 119 bits (298), Expect = 2e-26
Identities = 139/526 (26%), Positives = 227/526 (43%), Gaps = 51/526 (9%)
Query: 403 YLGYTVTWLP-SRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGHWSQVQTIHGTQIGSYF 460
YLGY+V + SG PR +G V ++ G + S + G Q+ +YF
Sbjct: 215 YLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYD----GKNMSSLYNFTGEQMAAYF 270
Query: 461 GGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQRRQLGFEEVSELQGDP 514
G + D++ D ++ IGAPLF Q G+V + +R G + ++L G
Sbjct: 271 GFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFE 329
Query: 515 GYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHGGLSPQPSQRIEG 571
+ RFG AI L D++ DG D+A+ AP +++G VYIFNGR GL+ PSQ +EG
Sbjct: 330 VF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEG 387
Query: 572 TQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTLMSFSPAE 628
+ FG S+ G D++ +G D+ VGA + I+ +RPV+ + + P+
Sbjct: 388 QWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSI 447
Query: 629 IPVHEVECSYSTSNKMKEGVNITICFQI--KSLIPQFQGRLVANLTYTLQLDGHRTRRRG 686
+ CS + N+ C + K ++P+ V L L+ G RR
Sbjct: 448 LNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG--AIRRA 505
Query: 687 LFPGGR---HELRRNIAVTTSMSCTDFSFHF--PVCVQDLISPINVSLNFSLWEEEGTPR 741
LF R H I+ M C + + +D ++PI + + + L
Sbjct: 506 LFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRL-------- 557
Query: 742 DQR--AQGKDIPPILR---PSLHSETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLT 796
D R A + PIL P+ S I + CGED C+ L VS + + + +
Sbjct: 558 DYRTAADTTGLQPILNQFTPANISRQAHILLD--CGEDNVCKPKLEVSVD-SDQKKIYIG 614
Query: 797 AFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLS 856
L++ + N E AY +L + P F V + + +SC E +
Sbjct: 615 DDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGV-VRNNEALARLSCAFKTENQ---T 670
Query: 857 RALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNN 902
R + C++ +P+ KAG + + F+ S SV+ + +N
Sbjct: 671 RQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSN 715
Score = 34.3 bits (77), Expect = 0.71
Identities = 13/30 (43%), Positives = 24/30 (80%)
Query: 1090 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1119
+++ +L+ + GLLLL ++ V+Y++GFFKR
Sbjct: 958 VWVIILAVLAGLLLLAVLVFVMYRMGFFKR 987
>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
sapiens]
Length = 462
Score = 110 bits (275), Expect = 8e-24
Identities = 121/441 (27%), Positives = 180/441 (40%), Gaps = 78/441 (17%)
Query: 762 TWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDL 821
T +PFEKNCG D C+ NL +SFS ++L + + L+ E+ + N ED+Y +
Sbjct: 11 TASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITF 70
Query: 822 HFPPGLSFRKVEMLKPHSQ---IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQM 878
P GLS+R V + Q + ++C+ P S+ + + SC ++ IF+ G +
Sbjct: 71 SHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQ-GTWSTSCRINHLIFRGGAQITFLA 129
Query: 879 MFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTI---IPILYPINILIQDQEDSTL 935
F+ + GD + L ANV+ N S TT +P+ Y + ++ E T
Sbjct: 130 TFDVSPKAVLGDRLLLTANVSSENN----TPRTSKTTFQLELPVKYAVYTVVSSHEQFTK 185
Query: 936 YVSFTPKGPK-IHQVKHMYQV----------------RIQPSIHDHNIPT--------LE 970
Y++F+ K H H YQ R P + +P ++
Sbjct: 186 YLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMD 245
Query: 971 AVVGVPQPPSE------------GPITHQW--SVQMEPPVPCHYEDLERLPDAAEPCLPG 1016
V PQ P + + W V E V C + L ++E P
Sbjct: 246 VEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIAPP 305
Query: 1017 A---------------------LFRCPV---VFRQEILVQVIGTLEL--VGEIEASSMFS 1050
A FRC V ++E+ + G L V +I S
Sbjct: 306 ASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQI-LQKKVS 364
Query: 1051 LCSSLSISFNSSKHFHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFI 1109
+ S I+F++S + L G A + AQ ++ L V S IGGLLLL LI
Sbjct: 365 VVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITA 424
Query: 1110 VLYKVGFFKRNLKEKMEAGRG 1130
VLYKVGFFKR KE ME G
Sbjct: 425 VLYKVGFFKRQYKEMMEEANG 445
>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
Length = 496
Score = 90.1 bits (222), Expect = 1e-17
Identities = 62/187 (33%), Positives = 97/187 (51%), Gaps = 13/187 (6%)
Query: 156 DLVFLFDGSMSLQPDEFQKILDFMKDVMKKL--SNTSYQFAAVQFSTSYKTEFDFSDYVK 213
DLVFL DGS S++P+ F+ + F+ ++ L S+ Q VQ+S+S + EF +
Sbjct: 275 DLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFHT 334
Query: 214 RKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNI 273
+KD A ++++ +M T T A+ Y+ F GARP A KV I+ TDG + D N
Sbjct: 335 KKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGRSQDYIN- 393
Query: 274 DAAK-----DIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKLKDLFTELQ 328
DAAK + +G+G ++ L + AS+P +E F+ + + +LQ
Sbjct: 394 DAAKKAKDLGFKMFAVGVG-----NAVEDELREIASEPVAEHYFYTADFKTINQIGKKLQ 448
Query: 329 KKIYVIE 335
KKI V E
Sbjct: 449 KKICVEE 455
Score = 75.9 bits (185), Expect = 2e-13
Identities = 58/213 (27%), Positives = 104/213 (48%), Gaps = 14/213 (6%)
Query: 131 LFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKL--SN 188
L Q L P L + C DLVF+ D S S++P EF+K+ F+ V++ L
Sbjct: 16 LLLQALCSPGLAPQSRGHLCRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGP 75
Query: 189 TSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREE 248
+ + V ++++ K EF +V + ++ ++ + T T AI + T+ F +
Sbjct: 76 NATRVGMVNYASTVKQEFSLRAHVSKAALLQAVRRIQPLSTGTMTGLAIQFAITKAFGDA 135
Query: 249 LGAR---PDATKVLIIITDGEATDS-GNIDA---AKDIIRYIIGIGKHFQTKESQETLHK 301
G R PD +KV+I++TDG DS ++ A A + + IG+G + TL +
Sbjct: 136 EGGRSRSPDISKVVIVVTDGRPQDSVQDVSARARASGVELFAIGVG-----SVDKATLRQ 190
Query: 302 FASKPASEFVKILDTFEKLKDLFTELQKKIYVI 334
AS+P E V ++++ ++ L + Q+ V+
Sbjct: 191 IASEPQDEHVDYVESYSVIEKLSRKFQEAFCVV 223
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 84.3 bits (207), Expect = 6e-16
Identities = 57/193 (29%), Positives = 101/193 (52%), Gaps = 14/193 (7%)
Query: 148 QECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKL--SNTSYQFAAVQFSTSYKTE 205
++C +G +DLVF+ DGS SL + F+ + F+ ++ L S + + +Q+ST TE
Sbjct: 647 KKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTE 706
Query: 206 FDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKV---LIII 262
F ++ KD + H+K+M + T A+ ++ F + GARP +T+V I+
Sbjct: 707 FTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVF 766
Query: 263 TDGEATDSGNIDAAK----DIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFE 318
TDG A D + A+K I Y +G+GK +E L + AS+P ++ + + F
Sbjct: 767 TDGRAQDDVSEWASKAKANGITMYAVGVGKAI-----EEELQEIASEPTNKHLFYAEDFS 821
Query: 319 KLKDLFTELQKKI 331
+ ++ +L+K I
Sbjct: 822 TMDEISEKLKKGI 834
Score = 79.3 bits (194), Expect = 2e-14
Identities = 53/191 (27%), Positives = 95/191 (49%), Gaps = 14/191 (7%)
Query: 150 CIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLS--NTSYQFAAVQFSTSYKTEFD 207
C DLVF+ D S S+ ++ K+ +F+ D+++ L + +Q+ ++ K EF
Sbjct: 51 CENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFS 110
Query: 208 FSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARP---DATKVLIIITD 264
+ ++ + + +K ++H+ T T AI Y F E GARP + +V++I+TD
Sbjct: 111 LKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTD 170
Query: 265 GEATDSGNIDAAK----DIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKL 320
G DS AAK I+ + IG+G + TL S+P + V ++ F ++
Sbjct: 171 GRPQDSVAEVAAKARDTGILIFAIGVG-----QVDFNTLKSIGSEPHEDHVFLVANFSQI 225
Query: 321 KDLFTELQKKI 331
+ L + QKK+
Sbjct: 226 ETLTSVFQKKL 236
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 84.3 bits (207), Expect = 6e-16
Identities = 57/193 (29%), Positives = 101/193 (52%), Gaps = 14/193 (7%)
Query: 148 QECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKL--SNTSYQFAAVQFSTSYKTE 205
++C +G +DLVF+ DGS SL + F+ + F+ ++ L S + + +Q+ST TE
Sbjct: 647 KKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTE 706
Query: 206 FDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKV---LIII 262
F ++ KD + H+K+M + T A+ ++ F + GARP +T+V I+
Sbjct: 707 FTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVF 766
Query: 263 TDGEATDSGNIDAAK----DIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFE 318
TDG A D + A+K I Y +G+GK +E L + AS+P ++ + + F
Sbjct: 767 TDGRAQDDVSEWASKAKANGITMYAVGVGKAI-----EEELQEIASEPTNKHLFYAEDFS 821
Query: 319 KLKDLFTELQKKI 331
+ ++ +L+K I
Sbjct: 822 TMDEISEKLKKGI 834
Score = 79.3 bits (194), Expect = 2e-14
Identities = 53/191 (27%), Positives = 95/191 (49%), Gaps = 14/191 (7%)
Query: 150 CIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLS--NTSYQFAAVQFSTSYKTEFD 207
C DLVF+ D S S+ ++ K+ +F+ D+++ L + +Q+ ++ K EF
Sbjct: 51 CENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFS 110
Query: 208 FSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARP---DATKVLIIITD 264
+ ++ + + +K ++H+ T T AI Y F E GARP + +V++I+TD
Sbjct: 111 LKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTD 170
Query: 265 GEATDSGNIDAAK----DIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKL 320
G DS AAK I+ + IG+G + TL S+P + V ++ F ++
Sbjct: 171 GRPQDSVAEVAAKARDTGILIFAIGVG-----QVDFNTLKSIGSEPHEDHVFLVANFSQI 225
Query: 321 KDLFTELQKKI 331
+ L + QKK+
Sbjct: 226 ETLTSVFQKKL 236
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,337,283
Number of Sequences: 37866
Number of extensions: 2344786
Number of successful extensions: 5588
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 5095
Number of HSP's gapped (non-prelim): 197
length of query: 1170
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1057
effective length of database: 13,968,660
effective search space: 14764873620
effective search space used: 14764873620
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.